UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 10-Q

   X     QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d)
OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended July 2, 20061, 2007

OR

TRANSITION REPORT PURSUANT TO SECTION 13
OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from________to_______

COMMISSION FILE NUMBER 1-3619

----

PFIZER INC.
(Exact name of registrant as specified in its charter)

   

DELAWARE
(State of Incorporation)

13-5315170
(I.R.S. Employer Identification No.)

    

235 East 42nd Street, New York, New York   10017
     (Address of principal executive offices)   (zip code)
(212) 573-2323
(Registrant's telephone number)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports) and (2) has been subject to such filing requirements for the past 90 days.

YES    X             NO     

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, or a non-accelerated filer. See definition of "accelerated filer and large accelerated filer" in Rule 12b-2 of the Exchange ActAct. (Check one):

Large accelerated filer  X                     Accelerated Filerfiler                     Non-accelerated filer

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).

YES                    NO     X   

At July 31, 2006, 7,291,451,351August 1, 2007, 6,927,108,833 shares of the issuer's voting common stock were outstanding.

FORM 10-Q

For the Quarter Ended
July 2, 20061, 2007

Table of Contents

PART I.  FINANCIAL INFORMATION

Page

   

Item 1.

Financial Statements:Statements

   

Condensed Consolidated Statements of Income for the three months and six months ended July 2, 20061, 2007, and July 3, 20052, 2006

3

   

Condensed Consolidated Balance Sheets atas of July 2, 20061, 2007, and December 31, 20052006

4

   

Condensed Consolidated Statements of Cash Flows for the six months ended July 2, 20061, 2007, and July 3, 20052, 2006

5

   

Notes to Condensed Consolidated Financial Statements

6

   

Review Report of Independent Registered Public Accounting Firm

2318

   

Item 2.

Management's Discussion and Analysis of Financial Condition and Results of Operations

2419

   

Item 3.

Quantitative and Qualitative Disclosures About Market Risk

5248

   

Item 4.

Controls and Procedures

5249

   

PART II.  OTHER INFORMATION

 

   

Item 1.

Legal Proceedings

5349

   

Item 1A.

Risk Factors

5451

   

Item 2.

Unregistered Sales of Equity Securities and Use of Proceeds

5452

   

Item 3.

Defaults Upon Senior Securities

5552

   

Item 4.

Submission of Matters to a Vote of Security Holders

5552

   

Item 5.

Other Information

5552

   

Item 6.

Exhibits

5553

   

Signature

5654

PART I - FINANCIAL INFORMATION

Item 1. Financial Statements.

PFIZER INC AND SUBSIDIARY COMPANIES
CONDENSED CONSOLIDATED STATEMENTS OF INCOME
(UNAUDITED)

Three Months Ended

Six Months Ended

Three Months Ended

Six Months Ended

(millions of dollars, except per common share data)

July 2, 
2006 

July 3, 
2005 

July 2, 
2006 

July 3, 
2005 

(millions, except per common share data)

July 1, 
2007 

July 2, 
2006 

July 1, 
2007 

July 2, 
2006

Revenues

$

11,741 

$

11,452 

$

23,488 

$

23,595 

$

11,084 

$

11,741 

$

23,558 

$

23,488 

Costs and expenses:

Cost of sales(a)

1,790 

1,762 

3,461 

3,639 

2,109 

1,790 

3,996 

3,461 

Selling, informational and administrative expenses(a)

3,881 

3,766 

7,276 

7,431 

3,844 

3,881 

7,205 

7,276 

Research and development expenses(a)

1,742 

1,830 

3,285 

3,547 

2,165 

1,742 

3,830 

3,285 

Amortization of intangible assets

823 

856 

1,648 

1,736 

783 

823 

1,598 

1,648 

Merger-related in-process research and development charges

513 

260 

513 

262 

Restructuring charges and merger-related costs

268 

264 

567 

480 

Acquisition-related in-process research and development charges

-- 

513 

283 

513 

Restructuring charges and acquisition-related costs

1,051 

268 

1,863 

567 

Other (income)/deductions - net

(359)

(198)

(615)

854 

(487)

(359)

(889)

(615)

Income from continuing operations before provision/(benefit) for taxes on income and minority interests

3,083 

2,912 

7,353 

5,646 

Income from continuing operations before provision for taxes on income and minority interests

1,619 

3,083 

5,672 

7,353 

Provision/(benefit) for taxes on income

790 

(464)

1,052 

2,111 

Provision for taxes on income

272 

790 

961 

1,052 

Minority interests

Income from continuing operations

2,290 

3,375 

6,296 

3,531 

1,345 

2,290 

4,706 

6,296 

Discontinued operations:

Income from discontinued operations - net of tax

108 

88 

210 

191 

-- 

108 

-- 

210 

Gains on sales of discontinued operations - net of tax

17 

-- 

20 

41 

Gains/(losses) on sales of discontinued operations - net of tax

(78)

17 

(47)

20 

Discontinued operations - net of tax

125 

88 

230 

232 

(78)

125 

(47)

230 

Net income

$

2,415 

$

3,463 

$

6,526 

$

3,763 

$

1,267 

$

2,415 

$

4,659 

$

6,526 

Earnings per common share - basic:

Income from continuing operations

$

0.31 

$

0.46 

$

0.86 

$

0.48 

$

0.19 

$

0.31 

$

0.67 

$

0.86 

Discontinued operations - net of tax

0.02 

0.01 

0.03 

0.03 

(0.01)

0.02 

(0.01)

0.03 

Net income

$

0.33 

$

0.47 

$

0.89 

$

0.51 

$

0.18 

$

0.33 

$

0.66 

$

0.89 

Earnings per common share - diluted:

Income from continuing operations

$

0.31 

$

0.46 

$

0.86 

$

0.48 

$

0.19 

$

0.31 

$

0.67 

$

0.86 

Discontinued operations - net of tax

0.02 

0.01 

0.03 

0.03 

(0.01)

0.02 

(0.01)

0.03 

Net income

$

0.33 

$

0.47 

$

0.89 

$

0.51 

$

0.18 

$

0.33 

$

0.66 

$

0.89 

Weighted-average shares used to calculate earnings per common share:

Basic

7,282 

7,366 

7,298 

7,391 

6,966 

7,282 

7,009 

7,298 

Diluted

7,305 

7,418 

7,330 

7,445 

6,990 

7,305 

7,033 

7,330 

Cash dividends paid per common share

$

0.24 

$

0.19 

$

0.48 

$

0.38 

$

0.29 

$

0.24 

$

0.58 

$

0.48 

(a)

Exclusive of amortization of intangible assets, except as disclosed in Note 12B, 10B. Goodwill and Other Intangible Assets: Other Intangible Assets.

See accompanying Notes to Condensed Consolidated Financial Statements.

PFIZER INC AND SUBSIDIARY COMPANIES
CONDENSED CONSOLIDATED BALANCE SHEETS

(UNAUDITED)

(millions of dollars)

July 2, 
2006*

Dec. 31, 
2005**

July 1, 
2007*

Dec. 31, 
2006**

ASSETS

Current Assets

Cash and cash equivalents

$

1,921 

$

2,247 

$

2,138 

$

1,827 

Short-term investments

12,829 

19,979 

20,115 

25,886 

Accounts receivable, less allowance for doubtful accounts

9,275 

9,103 

9,497 

9,392 

Short-term loans

511 

510 

540 

514 

Inventories

6,392 

5,478 

5,734 

6,111 

Prepaid expenses and taxes

3,262 

2,903 

3,564 

3,157 

Assets of discontinued operations and other assets held for sale

6,804 

6,659 

34 

62 

Total current assets

40,994 

46,879 

41,622 

46,949 

Long-term investments and loans

2,387 

2,497 

5,067 

3,892 

Property, plant and equipment, less accumulated depreciation

16,483 

16,233 

16,298 

16,632 

Goodwill

21,057 

20,985 

20,985 

20,876 

Identifiable intangible assets, less accumulated amortization

26,134 

26,244 

22,902 

24,350 

Other assets, deferred taxes and deferred charges

4,495 

4,860 

3,529 

2,138 

Total assets

$

111,550 

$

117,698 

$

110,403 

$

114,837 

LIABILITIES AND SHAREHOLDERS' EQUITY

Current Liabilities

Short-term borrowings, including current portion of long-term debt

$

3,779 

$

11,589 

$

2,432 

$

2,434 

Accounts payable

1,740 

2,073 

1,845 

2,019 

Dividends payable

1,757 

1,772 

2,010 

2,055 

Income taxes payable

4,356 

3,618 

516 

6,466 

Accrued compensation and related items

1,399 

1,602 

1,573 

1,903 

Other current liabilities

5,655 

6,564 

6,760 

6,510 

Liabilities of discontinued operations and other liabilities held for sale

1,369 

1,237 

-- 

Total current liabilities

20,055 

28,455 

15,136 

21,389 

Long-term debt

5,450 

6,347 

5,777 

5,546 

Pension benefit obligations

2,721 

2,681 

3,389 

3,632 

Postretirement benefit obligations

1,447 

1,424 

1,955 

1,970 

Deferred taxes

10,369 

10,392 

7,602 

8,015 

Other taxes payable

5,426 

-- 

Other noncurrent liabilities

3,019 

2,635 

3,024 

2,927 

Total liabilities

43,061 

51,934 

42,309 

43,479 

Shareholders' Equity

Shareholders' equity

Preferred stock

152 

169 

110 

141 

Common stock

440 

439 

442 

441 

Additional paid-in capital

68,217 

67,759 

69,555 

69,104 

Employee benefit trust, at fair value

(700)

(923)

(604)

(788)

Treasury stock

(41,755)

(39,767)

(51,833)

(46,740)

Retained earnings

40,627 

37,608 

50,304 

49,669 

Accumulated other comprehensive income

1,508 

479 

Accumulated other comprehensive income/(expense)

120 

(469)

Total shareholders' equity

68,489 

65,764 

68,094 

71,358 

Total liabilities and shareholders' equity

$

111,550 

$

117,698 

$

110,403 

$

114,837 

*    Unaudited.

**  Condensed from audited financial statements.

See accompanying Notes to Condensed Consolidated Financial Statements.

PFIZER INC AND SUBSIDIARY COMPANIES
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(UNAUDITED)

Six Months Ended

(millions of dollars)

July 2, 
2006 

July 3, 
2005 

   

Operating Activities:

Net income

$

6,526 

$

3,763 

Adjustments to reconcile net income to net cash provided by operating activities:

Depreciation and amortization

2,694 

2,776 

Share-based compensation expense

326 

79 

Merger-related in-process research and development charges

513 

262 

Intangible asset impairments and other associated non-cash charges

-- 

1,213 

Gains on disposal of investments, products and product lines

(114)

(53)

Gains on sales of discontinued operations

(31)

(65)

Deferred taxes from continuing operations

(438)

(931)

Other deferred taxes

45 

 93 

Other non-cash adjustments

219 

215 

Changes in assets and liabilities (net of businesses acquired and divested)

(636)

(369)

   

Net cash provided by operating activities

9,104 

6,983 

   

Investing Activities:

Purchases of property, plant and equipment

(887)

(997)

Purchases of short-term investments

(5,663)

(7,441)

Proceeds from redemptions of short-term investments

13,239 

12,570 

Purchases of long-term investments

(248)

(560)

Proceeds from sales of long-term investments

47 

568 

Purchases of other assets

(78)

(99)

Proceeds from sales of other assets

Proceeds from the sales of businesses, products and product lines

14 

101 

Acquisitions, net of cash acquired

(1,989)

(255)

Other investing activities

(116)

276 

   

Net cash provided by investing activities

4,322 

4,169 

   

Financing Activities:

Increase in short-term borrowings, net

938 

90 

Principal payments on short-term borrowings

(10,583)

(5,800)

Proceeds from issuances of long-term debt

1,054 

Principal payments on long-term debt

(2)

(22)

Purchases of common stock

(2,000)

(3,304)

Cash dividends paid

(3,468)

(2,930)

Stock option transactions and other

318 

278 

   

Net cash used in financing activities

(13,743)

(11,686)

Effect of exchange-rate changes on cash and cash equivalents

(9)

Net decrease in cash and cash equivalents

(326)

(532)

Cash and cash equivalents at beginning of period

2,247 

1,808 

   

Cash and cash equivalents at end of period

$

1,921 

$

1,276 

   

Supplemental Cash Flow Information:

Cash paid during the period for:

Income taxes

$

921 

$

1,296 

Interest

414 

329 

Six Months Ended

(millions of dollars)

July 1, 
2007 

July 2, 
2006 

   

Operating Activities:

Net income

$

4,659 

$

6,526 

Adjustments to reconcile net income to net cash provided by operating activities:

Depreciation and amortization

2,712 

2,694 

Share-based compensation expense

228 

326 

Acquisition-related in-process research and development charges

283 

513 

Gains on disposal of investments, products and product lines

(79)

(168)

(Gains)/losses on sales of discontinued operations

39 

(31)

Deferred taxes from continuing operations

(951)

(438)

Other deferred taxes

-- 

45 

Other non-cash adjustments

37 

270 

Changes in assets and liabilities (net of businesses acquired and divested)

(2,020)

(633)

   

Net cash provided by operating activities

4,908 

9,104 

   

Investing Activities:

Purchases of property, plant and equipment

(757)

(887)

Purchases of short-term investments

(10,738)

(5,663)

Proceeds from redemptions of short-term investments

17,101 

13,239 

Purchases of long-term investments

(1,243)

(248)

Proceeds from redemptions of long-term investments

22 

47 

Purchases of other assets

(82)

(78)

Proceeds from sales of other assets

29 

Proceeds from the sales of businesses, products and product lines

14 

14 

Acquisitions, net of cash acquired

(463)

(1,989)

Other investing activities

(336)

(116)

   

Net cash provided by investing activities

3,547 

4,322 

   

Financing Activities:

Increase in short-term borrowings, net

78 

938 

Principal payments on short-term borrowings

(763)

(10,583)

Proceeds from issuances of long-term debt

1,243 

1,054 

Principal payments on long-term debt

(60)

(2)

Purchases of common stock

(4,999)

(2,000)

Cash dividends paid

(4,040)

(3,468)

Stock option transactions and other

383 

318 

   

Net cash used in financing activities

(8,158)

(13,743)

Effect of exchange-rate changes on cash and cash equivalents

14 

(9)

Net increase/(decrease) in cash and cash equivalents

311 

(326)

Cash and cash equivalents at beginning of period

1,827 

2,247 

   

Cash and cash equivalents at end of period

$

2,138 

$

1,921 

   

Supplemental Cash Flow Information:

Cash paid during the period for:

Income taxes

$

3,672 

$

921 

Interest

354 

414 

See accompanying Notes to Condensed Consolidated Financial Statements.

PFIZER INC AND SUBSIDIARY COMPANIES
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
(UNAUDITED)

Note 1.  Basis of Presentation

We prepared the condensed consolidated financial statements following the requirements of the Securities and Exchange Commission (SEC) for interim reporting. As permitted under those rules, certain footnotes or other financial information that are normally required by accounting principles generally accepted in the United States of America (GAAP) can be condensed or omitted. Balance sheet amounts and operating results for subsidiaries operating outside the U.S. are as of and for the three-month and six-monthsix month periods ended May 28, 200627, 2007, and May 29, 2005.28, 2006.

We made certain reclassifications to the 2005 condensed consolidated financial statementsprior period amounts to conform to the 2006second-quarter 2007 presentation. These reclassifications are primarily related to discontinued operations (see Note 3, Discontinued Operations) as well as to better reflect jurisdictional netting of deferred taxes.

Revenues, expenses, assets and liabilities can vary during each quarter of the year. Therefore, the results and trends in these interim financial statements may not be representative of those for the full year.

We are responsible for the unaudited financial statements included in this document. The financial statements include all normal and recurring adjustments that are considered necessary for the fair presentation of our financial position and operating results.

The information included in this Quarterly Report on Form 10-Q should be read in conjunction with the consolidated financial statements and accompanying notes included in Pfizer's Annual Report on Form 10-K for the year ended December 31, 2005.2006.

Note 2.  Adoption of New Accounting Policy

As of January 1, 2007, we adopted the provisions of Financial Accounting Standards Board (FASB) Interpretation No. 48 (FIN 48), Accounting for Uncertainty in Income Taxes, an interpretation of SFAS 109, Accounting for Income Taxes, and supplemented by FASB Financial Staff Position FIN 48-1, Definition of Settlement in FASB Interpretation No. 48, issued May 2, 2007, and changed our policy related to the accounting for income tax contingencies. To understand the cumulative effect of these accounting changes, see Note 6A.Taxes on Income: Adoption of New Accounting Standard.

We continue to account for income taxcontingencies using a benefit recognition model.Beginning January 1, 2007, if we consider that a tax position is 'more likely than not' of being sustained upon audit, based solely on the technical merits of the position, we recognize the benefit. We measure the benefit by determining the amount that is greater than 50% likely of being realized upon settlement, presuming that the tax position is examined by the appropriate taxing authority that has full knowledge of all relevant information. These assessments can be complex and we often obtain assistance from external advisors.

Under the benefit recognition model, if our initial assessment fails to result in the recognition of a tax benefit, we regularly monitor our position and subsequently recognize the tax benefit: (i) if there are changes in tax law or analogous case law that sufficiently raise the likelihood of prevailing on the technical merits of the position to more likely than not; (ii) if the statute of limitations expires; or (iii) if there is a completion of an audit resulting in a favorable settlement of that tax year with the appropriate agency.

Liabilities associated with uncertain tax positions are now classified as current only when we expect to pay cash within the next 12 months. Interest and penalties, if any, continue to be recorded in Provision for taxes on income and are classified on the balance sheet with the related tax liability.

Prior to 2007, our policy had been to account for income tax contingencies based on whether we determined our tax position to be 'probable' under current tax law of being sustained, as well as an analysis of potential outcomes under a given set of facts and circumstances.In addition, we previously considered all tax liabilities as current once the associated tax year was under audit.

Note 3.  Acquisitions

On May 16,In the first quarter of 2007, we acquired BioRexis Pharmaceutical Corp., a privately held biopharmaceutical company with a number of diabetes candidates and a novel technology platform for developing new protein drug candidates, and Embrex, Inc., an animal health company that possesses a unique vaccine delivery system known as Inovoject, which enables baby chicks to be vaccinated while inside their eggs. In connection with these and other small acquisitions, we recorded $283 million, in Acquisition-related in-process research and development charges in the first quarter of 2007.

In the second quarter of 2006, we completed the acquisition of all of the outstanding shares of Rinat Neuroscience Corp., a biologics company with several new central-nervous-system product candidates. In connection with the acquisition, as part of our preliminary purchase price allocation,this and other smaller acquisitions, we recorded $478$513 million, pre-tax, in Merger-relatedAcquisition-related in-process research and development charges.charges in the second quarter of 2006.

On February 28, 2006, we completed the acquisition of the sanofi-aventis world-wideworldwide rights, including patent rights and production technology, to manufacture and sell Exubera, an inhaled form of insulin for use in adults with type 1 and type 2 diabetes, and the insulin-production business and facilities located in Frankfurt, Germany, previously jointly owned by Pfizer and sanofi-aventis, for approximately $1.4 billion (including transaction costs). In 2006, in connection with the acquisition, as part of our preliminaryfinal purchase price allocation, we recorded an intangible asset for$1.0 billion of developed technology rights, of approximately $1.0 billion, inventory valued at $218 million and goodwill of approximatelyinventory and $166 million of Goodwill, all of which have been allocated to our Human HealthPharmaceutical segment. The amortization of the developed technology rights will beis primarily included in Cost of Salessales.  Given the size and complexity of the acquisition, the fair valuation and allocation work is still being finalized and is expected to be completed in the third quarter. To the extent that our estimates need to be adjusted, we will do so. Prior to the acquisition, in connection with our collaboration agreement with sanofi-aventis, we recorded a research and development milestone due to us from sanofi-aventis of approximately $118 million ($71 million, after tax) in the first quarter of 2006 in Research and development expenses upon the approval of Exubera in January 2006 by the Food and Drug Administration (FDA).

Note 3.4.  Discontinued Operations

We evaluate our businesses and product lines periodically for strategic fit within our operations. As a result of our evaluation, we decided to sell a number of businesses and product lines, certain of which qualified for Discontinued operations treatment:

In June 2006, we entered into an agreement to sell our Consumer Healthcare business for approximately $16.6 billion in cash. This business comprises substantially all of our former Consumer Healthcare segment and other associated amounts, such as purchase-accounting impacts and merger-related costs, and restructuring and implementation costs related to our Adapting to Scale (AtS) productivity initiative, previously reported in the Corporate/Other segment. In addition, certain manufacturing facility assets and liabilities, which were previously part of our Human Health or Corporate/Other segment, are included in the planned sale of the Consumer Healthcare business. In connection with  the decision to sell this business, for all periods presented, the operating results associated with this business that will be discontinued have been reclassified into Discontinued operations - net of tax in the condensed consolidated statements of income and the assets and liabilities associated with this business that will be sold have been reclassified into Assets/Liabilities of discontinued operations and other assets/liabilities held for sale, as appropriate, on the condensed consolidated balance sheets. The divestiture of the Consumer Healthcare business is expected to close in late 2006 and is subject to customary closing conditions, including receipt of regulatory approvals.

In the first quarter of 2005, we sold the second of three European generic pharmaceutical businesses, which had been included in our Human Health segment, for 70 million euros (approximately $93 million) and recorded a gain of $57 million ($36 million, net of tax) in Gains on sales of discontinued operations - net of tax in the condensed consolidated statement of income. In addition, we recorded an impairment charge of $9 million ($6 million, net of tax) related to the third European generic business in Income from discontinued operations - net of tax in the condensed consolidated statement of income for the six months ended July 3, 2005.

The following amounts, primarily related to our Consumer Healthcare business which was sold in December 2006 for $16.6 billion, have been segregated from continuing operations and included in Discontinued operations - net of tax in the condensed consolidated statements of income:

Three Months Ended

Six Months Ended

Three Months Ended

Six Months Ended

(in millions)

July 2,
2006

July 3,
2005

  

July 2,
2006

July 3,
2005

(millions of dollars)

July 1, 
2007 

July 2, 
2006 

  

July 1, 
2007 

July 2, 
2006 

Revenues

$

1,027 

$

987 

$

1,946 

$

1,951 

$

-- 

$

1,027

$

-- 

$

1,946 

Pre-tax income

$

160 

$

134 

$

315 

$

290 

$

-- 

$

160 

$

-- 

$

315 

Provision for taxes on income

(52)

(46)

(105)

(99)

-- 

(52)

-- 

(105)

Income from operations of discontinued businesses - net of tax

108 

88 

210 

191 

-- 

108 

-- 

210 

Pre-tax gains on sales of discontinued businesses

26 

-- 

31 

65 

Pre-tax gains/(losses) on sales of discontinued businesses

(79)

26 

(39)

31 

Provision for taxes on gains

(9)

-- 

(11)

(24)

(9)

 (8)

(11)

Gains on sales of discontinued businesses - net of tax

17 

-- 

20 

41 

Discontinued operations-net of tax

$

125 

$

88 

$

230 

$

232 

Gains/(losses) on sales of discontinued operations - net of tax

(78)

17 

(47)

20 

Discontinued operations - net of tax

$

(78)

$

125 

$

(47)

$

230 

The following assetsFor a period of time, we will continue to generate cash flows and liabilities, primarily related to report income statement activity in continuing operations that are associated with our former Consumer Healthcare business. The activities that give rise to these impacts are transitional in nature and generally result from agreements that ensure and facilitate the orderly transfer of business have been segregatedoperations to the new owner. Included in continuing operations for the second quarter of 2007 were the following amounts associated with these transition service agreements that will no longer occur after the full transfer of activities to the new owner: Revenues of $50 million; Cost of sales of $45 million; Selling, informational and included in Assetsadministrative expense of discontinued operations and other assets held for sale$5 million; and LiabilitiesOther (income)/deduction-net of discontinued operations and other liabilities held for sale, as appropriate,$7 million in the condensed consolidated balance sheets:

(in millions)

July 2,
2006

Dec. 31,
2005

   

Accounts receivable, less allowance for doubtful accounts

$

742

$

661

Inventories

567

561

Prepaid expenses and taxes

81

71

Property, plant and equipment - net

986

1,002

Goodwill

2,756

2,789

Identifiable intangible assets, less accumulated amortization

1,643

1,557

Other assets, deferred taxes and deferred charges

29

18

Assets of discontinued operations and other assets held for sale

$

6,804

$

6,659

   

Current liabilities

$

610

$

538

Other

759

699

Liabilities of discontinued operations and other liabilities held for sale

$

1,369

$

1,237

Net cash flows of our discontinued operations from each of the categories of operating, investing and financing activities were not significant for the six months ended July 2, 2006 and July 3, 2005.

Note 4. Adoption of New Accounting Standards

On January 1, 2006, we adopted the provisions of Statement of Financial Accounting Standards (SFAS) No. 123R, Share-Based Payment, as supplemented by the interpretation provided by SEC Staff Accounting Bulletin (SAB) No. 107, issued in March 2005. (SFAS 123R replaced SFAS 123, Stock-Based Compensation, issued in 1995.) We have elected the modified prospective application transition method of adoption and, as such, prior-period financial statements have not been restated. Under this method, the fair value of all stock options granted or modified after adoption must be recognized in the consolidated statement of income, and total compensation cost related to nonvested awards not yet recognized, determined under the original provisions of SFAS 123, must also be recognized in the consolidated statement of income.

Prior to January 1, 2006, we accounted for stock options under Accounting Principle Board Opinion (APB) No. 25, Accounting for Stock Issued to Employees, an elective accounting policy permitted by SFAS 123. Under this standard, since the exercise price of our stock options granted is set equal to the market price on the date of the grant, we did not record any expense to the condensed consolidated statement of income related to stock options, unless certain original grant date terms were subsequently modified. However, as required, we disclosed, in the Notes to Consolidated Financial Statements, the pro forma expense impact of the stock option grants as if we had applied the fair-value-based recognition provisions of SFAS 123.

The adoption of SFAS 123R primarily impacted our accounting for stock options (see Note 14, Share-Based Payments).

Note 5.  Asset Impairment Charge

In the first six months of 2005, we recorded charges totaling $1.2 billion ($761 million, net2007: Revenues of tax) in connection with the decision to suspend$94 million; Cost of sales of Bextra. The pre-tax charge included $1.1 billion related to the impairment$80 million; Selling, informational and administrative expense of developed technology rights$7 million; and $7 million related to the write-off of machinery and equipment, both of which were included in Other (income)/deductions - netdeduction-net (see Note 12, Goodwill and Other Intangible Assets).of $9 million in income.

Note 6.5.  Adapting to Scale Productivity Initiative

We incurred the following costs in connection with our Adapting to Scale (AtS) productivity initiative, which was launched in early 2005:2005 and broadened in October 2006:

Three Months Ended

Six Months Ended

Three Months Ended

Six Months Ended

(millions of dollars)

July 2,
2006

July 3,
2005

July 2,
2006

July 3,
2005

July 1,
2007

July 2,
2006

July 1,
2007

July 2,
2006

  

  

  

Implementation costs(a)

$

180

$

33

$

365

$

33

$

317 

$

180 

$

491 

$

365 

Restructuring charges(b)

262

21

556

21

1,035 

262 

1,830 

556 

Total AtS costs

$

442

$

54

$

921

$

54

$

1,352 

$

442 

$

2,321 

$

921 

   

(a)

IncludedFor the second quarter of 2007, included in Cost of sales ($170 million), Selling, informational and administrative expenses ($79 million), Research and development expenses ($131 million) and Other (income)/deductions - net ($63 million income). For the second quarter of 2006, included in Cost of sales ($104 million),Selling, informational and administrative expenses ($58 million), Research and developmentexpenses ($40 million) and Other (income)/deductions - net ($22 million income) for.For the threefirst six months ended July 2,of 2007, included in Cost of sales ($264 million), Selling, informational and administrative expenses ($128 million), Research and development expenses ($162 million) and Other (income)/deductions - net ($63 million income). For the first six months of 2006, and included in Cost of sales ($228 million),Selling, informational and administrative expenses ($97 million), Research and developmentexpenses ($62 million) and Other (income)/deductions - net ($22 million income) for the six months ended July 2, 2006. Included in Cost of sales ($1 million), Selling, informational and administrative expenses ($21 million), and Research and developmentexpenses ($11 million) for the three months and six months ended July 3, 2005..

(b)

Included in Restructuring charges and merger-relatedacquisition-related costs.

Included inAtS costs associated with Discontinued operations - net of tax are additional pre-tax AtS costs of $7 million and $15 million for the three months and six months ended July 2, 2006.in 2006 were not significant.

Through July 2, 2006,1, 2007, the restructuring charges primarily relate to our plant network optimization efforts and the restructuring of our U.S.worldwide marketing and worldwide research and development operations, while the implementation costs primarily relate to system and process standardization, as well as the expansion of shared services.

The components of restructuring charges associated with AtS follow:

(millions of dollars)

Costs
Incurred
Through
July 2,
2006

Utilization
Through
July 2,
2006

 

Accrual
as of
July 2,
2006

(a)

Costs
Incurred
Through
July 1,
2007

Utilization
Through
July 1,
2007

 

Accrual
as of
July 1,
2007

(a)

  

  

Employee termination costs

$

635

$

528

$

107

$

2,664

$

1,306

$

1,358

Asset impairments

299

299

--

606

606

--

Other

61

22

39

294

197

97

$

995

$

849

$

146

Total

$

3,564

$

2,109

$

1,455

  

(a)

Included in Other current liabilities.liabilities ($1.2 billion)and Other noncurrent liabilities ($215 million).

During the three months and six months ended July 2, 2006,second quarter of 2007, we expensed $166 million and $331$821 million for Employee termination costs, $58 million and $177$93 million for Asset impairments and $121 million in Other. During the first six months of 2007, we expensed $1.6 billion for Employee termination costs, $116 million for Asset impairmentsand $38 million and $48$162 million in Other. Through July 2, 2006,1, 2007, costs incurred for Employee termination costs represent the approvedexpected reduction of the workforce by 5,096approximately 18,400 employees, mainly in research, manufacturing sales and research. We notified affected individuals and 4,714 employees were terminated assales. As of July 2, 2006.1, 2007, approximately 9,900 of these employees have been formally terminated. Employee termination costs are recorded as incurredwhen the actions are probable and estimable and include accrued severance benefits, pension and postretirement benefits. Asset impairments primarily include charges to write off inventory and write down property, plant and equipment. Other primarily includes costs to exit certain activities.

Note 7.  Merger-Related Costs

We incurred the following merger-related costs:

Three Months Ended

Six Months Ended

(millions of dollars)

July 2,
2006

July 3,
2005

July 2,
2006

July 3,
2005

  

  

Integration costs

$

3

$

191

$

5

$

293

Restructuring charges

3

52

6

166

Total merger-related costs(a)

$

6

$

243

$

11

$

459

(a)

Included in Restructuring charges and merger-related costs. Amounts in 2005 primarily relate to our acquisition of Pharmacia Corporation (Pharmacia), which was completed on April 16, 2003.

Included in Discontinued operations - net of tax are additional pre-tax merger-related costs of $4 million and $5 million for the three months and six months ended July 2, 2006 and $9 million and $16 million for the three months and six months ended July 3, 2005.

Restructuring charges included severance, costs of vacating duplicative facilities, contract termination and other exit costs.

Note 8.6.  Taxes on Income

A.  Adoption of New Accounting Standard

As of January 1, 2007, we adopted the provisions of FIN 48, Accounting for Uncertainty in Income Taxes, an interpretation of SFAS 109, Accounting for Income Taxes, as supplemented by FASB Financial Staff Position FIN 48-1, Definition of Settlement in FASB Interpretation No. 48, issued May 2, 2007. See Note 2.Adoption of New Accounting Policy, for a full description of our accounting policy related to the accounting for income tax contingencies. As a result of the implementation of FIN 48, at the date of adoption, we reduced our existing liabilities for uncertain tax positions by approximately $11 million, which has been recorded as a direct adjustment to the opening balance of Retained earnings and changed the classification of virtually all amounts associated with uncertain tax positions approximately $4.0 billion, including the associated accrued interest of approximately $780 million, from current to noncurrent. For details, see section C. Tax Contingencies below.

B.  Taxes on Income

On January 23, 2006, the Internal Revenue Service (IRS) issued final regulations on Statutory Mergers and Consolidations, which impacted certain prior-period transactions. In the first quarter of 2006, we recorded a tax benefit of $217 million, reflecting the total impact of these regulations.

In the first six months of 2005, we recorded an income tax charge of $1.7 billion, included in Provision/(benefit) for taxes on income, in connection with our decision to repatriate about $37 billion of foreign earnings in accordance with the American Jobs Creation Act of 2004 (the Jobs Act). In the first quarter of 2005, we recorded an initial estimate of $2.2 billion based on the decision to repatriate $28.3 billion of foreign earnings; in the second quarter of 2005, we reduced our original estimate of the tax charge by $490 million, due primarily to guidance issued by the U.S. Treasury in the second quarter of 2005, partially offset by our decision to increase the amount of the repatriation.

B.Tax Contingencies

On January 25, 2006, the Company waswe were notified by the IRS Appeals Division that a resolution had been reached on the matter that we were in the process of appealing related to the tax deductibility of aan acquisition-related breakup fee paid by Warner-Lambert Company in 2000. As a result, in the first quarter of 2006, we recorded a tax benefit of approximately $441 million related to the resolution of this issue.issue.

InAs of July 1, 2007, we intend to permanently reinvest the second quarterearnings of 2005,our international subsidiaries and, therefore, we have not recorded a U.S. tax benefitprovision on unremitted earnings.

C.Tax Contingencies

We are subject to income tax in many jurisdictions and a certain degree of $586 million primarilyestimation is required in recording the assets and liabilities related to income taxes. For a description of our accounting policy associated with accounting for income taxcontingencies, see Note 2.Adoption of New Accounting Policy. All of our tax positions are subject to audit by the local taxing authorities in each tax jurisdiction. Tax audits can involve complex issues and the resolution of certainissues may span multiple years, particularly if subject to negotiation or litigation.

The United States is one of our major tax positions.

Thejurisdictions and the IRS is currently conducting audits of the Pfizer Inc. tax returns for the years 2002, 2003 and 2004. The 2005, 2006 and 20062007 tax years are also currently under audit underas part of the IRS Compliance Assurance Process (CAP), a recently introduced real-time audit process.

All other tax years in the U.S. for Pfizer Inc. are closed under the statute of limitations. With respect to Pharmacia Corporation, the IRS has completed audits of the tax returns for the years 2000 through 2002 and is currently conducting an audit for the year 2003 tax year through the date of the merger with Pfizer (April 16, 2003). Although the U.S. audits for Pharmacia Corporation for all previous years have been closed, tax years 2000 through 2002 are still open under the statute of limitations. In addition to the open audit years in the U.S., we have open audit years in other major tax jurisdictions, such as Canada (1998-2006), Japan (2004-2006), Europe (1996-2006, primarily reflecting Ireland, the U.K., France, Italy, Spain and Germany), and Puerto Rico (2002-2006).

We periodically reassessregularly reevaluate our tax positions and the likelihood of assessmentsassociated interest and penalties, if applicable, resulting from audits of federal, state and foreign income tax filings.filings, as well as changes in tax law that would either increase or decrease the technical merits of a position relative to the more likely than not standard. We believe that our accruals for tax liabilities are adequate for all open years. Many factors are considered in making these evaluations, including past history, recent interpretations of tax law, and the specifics of each matter. Because tax regulations are subject to interpretation and tax litigation is inherently uncertain, these evaluations can involve a series of complex judgments about future events and can rely heavily on estimates and assumptions. Our evaluations are based on estimates and assumptions that have been deemed reasonable by management. However, if our estimates and assumptions are not representative of actual outcomes, our results could be materially impacted.

Because tax law is complex and often subject to varied interpretations, it is uncertain whether some of our tax positions will be sustained upon audit. The amounts associated with uncertain tax positions are as follows:

(millions of dollars)

July 1,
2007

January 1,
2007

   

Non-current deferred tax assets(a)

$

451 

$

395 

Other tax assets(a)

726 

647 

Income taxes payable(b)

(135)

(47)

Other taxes payable(b)

(5,426)

(4,962)

Total amounts associated with uncertain tax positions

$

(4,384)

$

(3,967)

(a)

Included in Other assets, deferred taxes and deferred charges.

(b)

Includes gross accrued interest. Accrued penalties are not significant.

Tax liabilities associated with uncertain tax positions represent unrecognized tax benefits, which arise when the estimated benefit recorded in our financial statements differs from the amounts taken or expected to be taken in a tax return because of the uncertainties described above. These unrecognized tax benefits relate primarily to issues common among multinational corporations. Virtually all of these unrecognized tax benefits, if recognized, would impact our effective income tax rate.

Tax assets associated with uncertain tax positions represent our estimate of the potential tax benefits in one tax jurisdiction that could result from the payment of income taxes in another tax jurisdiction. These potential benefits generally result from cooperative efforts among taxing authorities to minimize double taxation. The recoverability of these assets, which we believe to be more likely than not, is dependent upon the actual payment of taxes in one tax jurisdiction and, in some cases, the successful petition for recovery in another tax jurisdiction.

If our estimates of unrecognized tax benefits and potential tax benefits are not representative of actual outcomes, our financial statements could be materially affected in the period of settlement as we treat settlements as discrete items in the period of resolution. Based on the protocol of finalizing audits by the relevant taxing authorities, which could include formal administrative and legal proceedings, except for amounts reflected in Income taxes payable, we are unable to estimate the range of reasonably possible change related to our uncertain tax positions within the next 12 months. However, any settlements would likely result in a significant decrease in our uncertain tax positions.

Note 9.7.  Comprehensive Income

The components of comprehensive income/(expense) follow:

Three Months Ended

Six Months Ended

Three Months Ended

Six Months Ended

(millions of dollars)

(millions of dollars)

July 2, 
2006 

July 3, 
2005 

July 2, 
2006 

July 3, 
2005 

July 1, 
2007 

July 2, 
2006 

July 1, 
2007 

July 2, 
2006 

  

  

Net income

Net income

$

2,415 

$

3,463 

$

6,526 

$

3,763 

$

1,267 

$

2,415 

$

4,659 

$

6,526 

Other comprehensive income/(expense):

Other comprehensive income/(expense):

Currency translation adjustment and other(a)

Currency translation adjustment and other(a)

688 

(708)

998 

(985)

Currency translation adjustment and other(a)

500 

688 

372 

998 

Net unrealized gains/(losses) on derivative financial instruments(b)

Net unrealized gains/(losses) on derivative financial instruments(b)

22 

(8)

93 

(27)

Net unrealized gains/(losses) on derivative financial instruments(b)

22 

18 

93 

Net unrealized gains/(losses) on available-for-sale securities(b)

Net unrealized gains/(losses) on available-for-sale securities(b)

(36)

(48)

(33)

(119)

Net unrealized gains/(losses) on available-for-sale securities(b)

(36)

(33)

Minimum pension liability(b)

 (17) 

16 

(29)

14 

Benefit plan adjustments

113 

(17) 

194  

(29)

Total other comprehensive income/(expense)

Total other comprehensive income/(expense)

657 

(748)

1,029 

(1,117)

631 

657 

589 

1,029 

Total comprehensive income

Total comprehensive income

$

3,072 

$

2,715 

$

7,555 

$

2,646 

$

1,898 

$

3,072 

$

5,248 

$

7,555 

 

(a)

Includes changes in currency translation adjustments of $19 million and $21 million for the three months and six months ended July 2, 2006, and  ($17) million and ($25) million for the three months and six months ended July 2, 2005 related to discontinued operations.

 

(b)

Amounts associated with discontinued operations are not significant.

 

Amounts of comprehensive income associated with discontinued operations in 2006 were not significant.

Note 10.8.  Financial Instruments

A.  Long-Term Debt

On February 22, 2006,May 11, 2007, we issued the following Japanese yen fixed-rate bonds,notes to be used for general corporate purposes:

$508 million equivalent, senior unsecured notes, due February 2011, which pay interest semi-annually, beginning on August 22, 2006, at a rate of 1.2%; and

$1.2 billion equivalent, senior, unsecured, euro-denominated notes, due May 15, 2017, which pay interest annually, beginning on May 15, 2008, at a fixed rate of 4.55%.

  

$466 million equivalent, senior unsecured notes, due February 2016, which pay interest semi-annually, beginning on August 22, 2006, at a rate of 1.8%.

The notes were issued under a $5 billion debt shelfnew securities registration statement filed with the SEC in November 2002. As of July 2, 2006, we had the ability to borrow approximately $1 billion by issuing debt securities under that debt shelf registration statement.

In May 2006, we decided to exercise Pfizer's option to call, at par-value plus accrued interest, $1 billion of senior unsecured floating-rate notes, which were included in Long-term debt as of December 31, 2005 and included in Short-term debt as of July 2, 2006. Notice to call was given to the Trustees and the notes were redeemed early in the third quarter of 2006.March 2007.

B.  Derivative Financial Instruments and Hedging Activities

There was no material ineffectiveness in any hedging relationship reported in earnings in the first six months of 2006.2007.

Foreign Exchange Risk

During the first six months of 2006,2007, we entered into the following new or incremental hedging or offset activities:

Instrument(a)

Primary
Balance Sheet
Caption

(b)

  

Hedge
Type

(c)

  

Hedged or Offset Item

Notional Amount as of
July 2, 2006
(millions of dollars)

Maturity Date

Forward

OCL

--

Short-term foreign currency assets and liabilities(d)

$1,074             

2006

Forward

Prepaid

CF

Euro intercompany loan

  

792             

2006

LT yen debt

LTD

NI

Yen net investments

523             

2011

LT yen debt

LTD

NI

Yen net investments

480             

2016

Instrument(a)

Primary
Balance Sheet
Caption

(b)

  

Hedge
Type

(c)

  

Hedged or Offset Item

Notional Amount as of
July 1, 2007
(millions of dollars)

Maturity Date

Forwards

OCL

--

Short-term foreign currency assets and liabilities(d)

$ 2,651            

2007

Forwards

Prepaid

CF

Yen available-for-sale investments

 2,212            

2007

Swap

ONCL

--

Euro fixed rate debt

1,216            

2017

Forwards

OCL

CF

Euro available-for-sale investments

1,041            

2007

Forwards

Prepaid

CF

Euro available-for-sale investments

696            

2007

Swap

Other assets

FV

Swiss franc loan

143            

2009

   

(a)

ForwardForwards = Forward-exchange contracts; LT yen debt = Long-term yen debtcontracts.

(b)

The primary balance sheet caption indicates the financial statement classification of the fair value amount associated with the financial instrument used to hedge foreign exchange risk. OCL = Other current liabilities;The abbreviations used are defined as follows: Prepaid = Prepaid expenses and taxes; LTDtaxes; Other assets = Long-term debtOther assets, deferred taxes and deferred charges; OCL = Other current liabilities; andONCL = Other noncurrent liabilities.

(c)

CF = Cash flow hedge; NIFV = Net investment hedgeFair value hedge.

(d)

Forward-exchange contracts used to offset short-term foreign currency assets and liabilities wereare primarily for intercompany transactions in euros, U.K. pounds, Japanese yen Canadian dollars, U.K. pounds and AustralianCanadian dollars.

These foreign exchangeforeign-exchange instruments serve to protect us against the impact of the translation into U.S. dollars of certain foreign exchangecurrency denominated transactions.

Interest Rate Risk

During the first six months of 2007, we entered into the following new hedging activities:

Instrument

Primary
Balance Sheet
Caption

(a)

  

Hedge
Type

(b)

  

Hedged Item

Notional Amount as of
July 1, 2007
(millions of dollars)

Maturity Date

Swap

ONCL

FV

Euro fixed rate debt

$ 1,216             

2017

Swaps

ONCL

CF

Available-for-sale investments

 646            

2009

(a)

The primary balance sheet caption indicates the financial statement classification of the fair value amount associated with the financial instrument used to hedge interest rate risk. The abbreviation used is defined as follows: ONCL = Other noncurrent liabilities.

(b)

FV = Fair value hedge; CF = Cash flow hedge.

The interest rate instruments serve to hedge the fixed or variable interest rates on the hedged items, matching the amount and timing of the hedged items.

Note 11.9.  Inventories

The components of inventories follow:

(millions of dollars)

(millions of dollars)

July 2,
2006

Dec. 31,
2005

(millions of dollars)

July 1,
2007

Dec. 31,
2006

Finished goods

Finished goods

$

2,223

$

1,742

Finished goods

$

1,898

$

1,651

Work-in-process

Work-in-process

3,153

2,379

Work-in-process

2,624

3,198

Raw materials and supplies

Raw materials and supplies

1,016

1,357

Raw materials and supplies

1,212

1,262

Total inventories(a)

Total inventories(a)

$

6,392

$

5,478

Total inventories(a)

$

5,734

$

6,111

 

    

 

(a)

Increase primarily due to the acquisition of sanofi-aventis' Exubera inventory, the build-up of inventory in advance of product launches and the impact of foreign exchange.

 

Note 12.10.  Goodwill and Other Intangible Assets

A.  Goodwill

The changes in the carrying amount of goodwill by segment for the six months ended July 2, 20061, 2007, follow:

(millions of dollars)

Human 
Health 

Animal 
Health 

Other 

Total 

Pharmaceutical 

Animal 
Health 

Other 

Total

Balance, December 31, 2005

$

20,919 

$

56 

$

10 

$

20,985 

Balance, December 31, 2006

$

20,798 

$

61 

$

17 

$

20,876

Additions(a)

166 

-- 

-- 

166 

-- 

39 

-- 

39

Other(b)

(99)

-- 

(94)

69 

-- 

70

Balance, July 2, 2006

$

20,986 

$

61 

$

10 

$

21,057 

Balance, July 1, 2007

$

20,867 

$

100 

$

18 

$

20,985

  

(a)

Primarily related to Exubera.Embrex, Inc.

(b)

Includes a reduction to goodwill related to the resolution of certain tax positions, partially offset by the impact of foreign exchange.exchange, partially offset by adjustments to certain purchase accounting liabilities.

B.  Other Intangible Assets

The components of identifiable intangible assets, primarily included in our Human HealthPharmaceutical segment, follow:

July 2, 2006

Dec. 31, 2005

July 1, 2007

Dec. 31, 2006

(millions of dollars)

Gross 
Carrying 
Amount 

Accumulated 
Amortization 

Gross 
Carrying 
Amount 

Accumulated 
Amortization 

Gross 
Carrying 
Amount 

Accumulated 
Amortization 

Gross 
Carrying 
Amount 

Accumulated 
Amortization 

Finite-lived intangible assets:

Developed technology rights

$

32,426 

$

(10,637)

$

30,729 

$

(8,810)

$

32,993 

$

(14,093)

$

32,769 

$

(12,423)

Brands

887 

(73)

885 

(51)

1,016 

(434)

888 

(417)

License agreements

155 

(34)

152 

(27)

209 

(50)

189 

(41)

Trademarks

109 

(69)

106 

(65)

117 

(75)

113 

(73)

Other(a)

518 

(247)

446 

(203)

529 

(285)

508 

(266)

Total amortized finite-lived intangible assets

34,095 

(11,060)

32,318 

(9,156)

34,864 

(14,937)

34,467 

(13,220)

Indefinite-lived intangible assets:

Brands

2,990 

-- 

2,990 

-- 

2,863 

-- 

2,991 

-- 

Trademarks

79 

-- 

79 

-- 

77 

-- 

77 

-- 

Other(b)

30 

-- 

13 

-- 

35��

-- 

35 

-- 

Total indefinite-lived intangible assets

3,099 

-- 

3,082 

-- 

2,975 

-- 

3,103 

-- 

Total identifiable intangible assets

$

37,194 

$

(11,060)

$

35,400 

$

(9,156)

$

37,839 

$

(14,937)

$

37,570 

$

(13,220)

  

Total identifiable intangible assets, less accumulated amortization

$

26,13422,902

  

$

26,24424,350

  

(a)

Includes patents, non-compete agreements, customer contracts and other intangible assets.

(b)

Includes pension-related intangible assets.

In the first six months of 2006, we acquired the sanofi-aventis worldwide rights, including patent rights and production technology, to manufacture and sell Exubera. In connection with the acquisition, we recorded an intangible asset for developed technology rights of approximately $1.0 billion. The amortization of these developed technology rights will be primarily included in Cost of Sales.

In the first six months of 2005, we recorded an impairment charge of $1.1 billion in Other (income)/deductions - net related to the developed technology rights for Bextra, a selective COX-2 inhibitor (included in our Human Health segment) in connection with the decision to suspend sales of Bextra. In addition, in connection with the suspension, we recorded $7 million related to the write-off of machinery and equipment included in Other (income)/deductions - net; $56 million in write-offs of inventory and exit costs, included in Cost of sales; $5 million related to the costs of administering the suspension of sales, included in Selling, informational and administrative expenses; and $173 million for an estimate of customer returns, primarily included against Revenues. Substantially all of these charges were recorded in the first quarter of 2005.

Amortization expense related to acquired intangible assets that contribute to our ability to sell, manufacture, research, market and distribute our products, compounds and intellectual property are included in Amortization of intangible assets as they benefit multiple business functions. Amortization expense related to acquired intangible assets that are associated with a single function are included in Cost of sales, Selling, informational and administrative expensesor,and Research and development expenses, as appropriate. Total amortization expense for finite-lived intangible assets was $848 million and $874$826 million for the three months ended July 2,second quarter of 2007 and $848 million for the second quarter of 2006, and July 3, 2005, and $1.7 billion and $1.8 billion for the first six months ended July 2, 2006of both 2007 and July 3, 2005.

Included in Discontinued operations - net2006. Amounts of tax is additional pre-tax amortization expense for finite-lived intangible assets of $4 million and $3 million for the three months ended July 2,associated with discontinued operations in 2006 and July 3, 2005 and $7 million and $5 million for the six months ended July 2, 2006 and July 3, 2005.were not significant.

The expected annual amortization expense expected for the fiscal years 2006 through 2011 is $3.4 billion in 2006; $3.3 billion in 2007; $2.7$2.8 billion in 2008; and $2.5$2.6 billion in 2009,2009; $2.5 in each of 2010 and 2011.2011; and $2.3 billion in 2012.

Note 13.11.  Pension and Postretirement Benefit Plans

The components of net periodic benefit costcosts of the U.S. and international pension plans and the postretirement plans, which provide medical and life insurance benefits to retirees and their eligible dependents, for the three months ended July 1, 2007, and July 2, 2006, and July 3, 2005 follow:

Pension Plans

Pension Plans

U.S. Qualified

U.S. Supplemental
(Non-Qualified)

International

Postretirement Plans

U.S. Qualified

U.S. Supplemental
(Non-Qualified)

International

Postretirement Plans

(millions of dollars)

2006 

2005 

2006

2005

2006 

2005  

2006 

2005 

2007 

2006 

2007

2006

2007 

2006  

2007 

2006 

Service cost

$

92 

$

80 

$

11 

$

10 

$

75 

$

76 

$

12 

$

10 

$

71 

$

92 

$

$

 11 

$

72 

$

75 

$

11 

$

12 

Interest cost

112 

102 

15 

14 

76 

78 

31 

28 

111 

112 

14 

15 

86 

76 

35 

31 

Expected return on plan assets

(154)

(149)

-- 

-- 

(79)

(80)

(6)

(5)

(170)

(154)

--  

-- 

(94)

(79)

(9)

(6)

Amortization of:

Actuarial losses

15 

28 

11 

10 

23 

25 

Prior service costs/(credits)

(1)

-- 

-- 

(1)

-- 

(1)

-- 

-- 

Net transition obligation

-- 

-- 

-- 

-- 

-- 

-- 

Actuarial losses

28 

25 

10 

25 

23 

Curtailments and settlements - net

21 

-- 

-- 

10 

12 

-- 

21 

(2)

(5)

(2)

12 

Special termination benefits

-- 

-- 

-- 

-- 

-- 

-- 

Less: amounts included in discontinued operations

(4)

(4)

(1)

(1)

(4)

(4)

(1)

(1)

--  

(4)

-- 

(1)

-- 

(4)

-- 

(1)

Net periodic benefit costs

$

101 

$

57 

$

35 

$

33 

$

108 

$

107 

$

59 

$

36 

$

36 

$

101 

$

30 

$

35 

$

84 

$

108 

$

48 

$

59 

The components of net periodic benefit costcosts of the U.S. and international pension plans and the postretirement plans, which provide medical and life insurance benefits to retirees and their eligible dependents, for the first six months ended July 2,of 2007 and 2006, follow:

Pension Plans

U.S. Qualified

U.S. Supplemental
(Non-Qualified)

International

Postretirement Plans

(millions of dollars)

2007 

2006 

2007

2006

2007 

2006  

2007 

2006 

   

Service cost

$

148 

$

186 

$

14 

$

22 

$

145 

$

149 

$

22 

$

24 

Interest cost

234 

224 

28 

30 

172 

150 

69 

63 

Expected return on plan assets

(360)

(315)

--  

-- 

(188)

(156)

(18)

(14)

Amortization of:

Actuarial losses

35 

59 

23 

 21

47 

51 

21 

17 

Prior service costs/(credits)

(1)

(1)

-- 

-- 

Curtailments and settlements - net

13 

25 

-- 

(105)

-- 

15 

Special termination benefits

10 

-- 

-- 

11 

Less: amounts included in discontinued operations

--  

(8)

-- 

(1)

-- 

(8)

-- 

(2)

Net periodic benefit costs

$

81 

$

185 

$

69 

$

71 

$

76 

$

207 

$

102 

$

109 

Japanese pension regulations permit employers with certain pension obligations to separate the social security benefits portion of those obligations and July 3, 2005 follow:transfer it, along with related plan assets, to the Japanese government. During the first quarter of 2007, our Japanese affiliate completed this transfer and effectively received a subsidy from the Japanese government of approximately $168 million. This subsidy was the result of the transfer of pension obligations of approximately $309 million (excluding the effect of any future salary increases of approximately $9 million) along with related plan assets of approximately $141 million. This transfer resulted in a settlement gain of approximately $106 million.

Pension Plans

U.S. Qualified

U.S. Supplemental
(Non-Qualified)

International

Postretirement Plans

(millions of dollars)

2006 

2005 

2005 

2005 

2006 

2005 

2006 

2005 

Service cost

$

186 

$

159 

$

22 

$

19 

$

149 

$

153 

$

24 

$

19 

Interest cost

224 

206 

30 

29 

150 

158 

63 

56 

Expected return on plan assets

(315)

(297)

-- 

-- 

(156)

(161)

(14)

(11)

Amortization of:

Prior service costs/(credits)

(1)

-- 

(1)

-- 

Net transition obligation

-- 

-- 

-- 

-- 

-- 

-- 

Actuarial losses

59 

51 

21 

19 

51 

48 

17 

10 

Curtailments and settlements - net

25 

-- 

-- 

-- 

10 

15 

-- 

Special termination benefits

10 

-- 

-- 

-- 

11 

10 

-- 

Less: amounts included in discontinued operations

(8)

(8)

(1)

(1)

(8)

(7)

(2)

(2)

Net periodic benefit costs

$

185 

$

118 

$

71 

$

67 

$

207 

$

211 

$

109 

$

72 

For the first six months of 2006,2007, we contributed from the Company'sour general assets $59$3 million to our U.S. qualified pension plans, $48 million to our U.S. supplemental (non-qualified) pension plans, $294$234 million to our international pension plans and $88$79 million to our postretirement plans. In July 2006, we made voluntary tax-deductible contributions in excess of minimum funding requirements of $450 million to certain of our U.S. qualified pension plans and voluntary tax-deductible contributions of $90 million to certain of our postretirement plans.

During 2006,2007, we expect to contribute, from the Company'sour general assets, a total of $453$105 million to our U.S. qualified pension plans, $76$68 million to our U.S. supplemental (non-qualified) pension plans, $449$442 million to our international pension plans and $253$158 million to our postretirement plans. Contributions expected to be made for 20062007 are inclusive of amounts contributed during the first six months of 2006 and voluntary contributions made in July 2006.2007. The contributions from the Company'sour general assets include direct employer benefit payments. Amounts associated with discontinued operations are not significant.

Note 14.12.  Share-Based Payments

Our compensation programs can include share-based payments. In 2006 and 2005, the primary share-based awards and their generalterms and conditions are as follows:

StockWe make our major annual grant of stock options, which entitle the holder to purchase, at the end of a vesting term, a specified number of shares of Pfizer common stock at a price per share set equal to the market price of Pfizer common stock on the date of grant.

Restricted stock units (RSUs), which entitle the holder to receive, at the end of a vesting term, a specified number of shares of Pfizer common stock, including shares resulting from dividend equivalents paid on such RSUs.

Performance share awards (PSAs) and performance-contingent share awards (PCSAs), which entitle the holder to receive, at the end of a vesting term, a number of shares of Pfizer common stock, within a range of shares from zero to a specified maximum, calculated using a non-discretionary formula that measures Pfizer's performance relative to an industry peer group.

Restricted stock grants, which entitle the holder to receive, at the end of a vesting term, a specified number of shares of Pfizer common stock, and which also entitle the holder to receive dividends paid on such grants.

The Company's shareholders approved the Pfizer Inc. 2004 Stock Plan (the 2004 Plan) at the Annual Meeting of Shareholders held on April 22, 2004 and, effective upon that approval, new stock option and other share-based awards may be granted only under the 2004 Plan. The 2004 Plan allows a maximum of 3 million shares to be awarded to any employee per year and 475 million shares in total. RSUs, PSAs, PCSAs and restricted stock grants count as three shares while stock options count as oneunits and performance share underawards in the 2004 Plan towardfirst quarter of each year. Net income included the maximums.

In the past, we had various employee stock and incentive plans under which stock options and otherfollowing share-based awards were granted. Stock options and other share-based awards that were granted under prior plans and were outstanding on April 22, 2004 continue in accordance with the terms of the respective plans.

As of July 2, 2006, 305 million shares were available for award, which include 26 million shares available for award under the legacy Pharmacia Long-Term Incentive Plan, which reflects award cancellations returned to the pool of available shares for legacy Pharmacia commitments.

Although not required to do so, historically, we have used authorized and unissued shares and, to a lesser extent, shares held in our Employee Benefit Trust to satisfy our obligations under these programs.

A.  Impact on Net Income

The components of share-based compensation expense and the associated tax benefit follow:benefit:

Three Months Ended

Six Months Ended

Three Months Ended

Six Months Ended

(millions of dollars)

July 2, 
2006 

July 3, 
2005 

July 2, 
2006 

July 3, 
2005 

July 1, 
2007 

July 2, 
2006 

July 1, 
2007 

July 2, 
2006 

  

  

  

  

  

  

Stock option expense

$

100 

$

-- 

$

221 

$

-- 

$

51 

$

100 

$

154 

$

221 

Restricted stock unit expense

50 

37 

90 

51 

42 

50 

96 

90 

Performance share awards and performance-contingent share awards expense

20 

15 

28 

(6)

(22)

15 

Share-based payment expense

154 

57 

326 

79 

87 

154 

228 

326 

Tax benefit for share-based compensation expense

(45)

(20)

(93)

(27)

(30)

(45)

(71)

(93)

Share-based payment expense, net of tax

$

109 

$

37 

$

233 

$

52 

$

57 

$

109 

$

157 

$

233 

Included in Discontinued operations - net of tax is additional share-based compensation expense as shown in the following table:

Three Months Ended

Six Months Ended

(millions of dollars)

July 2, 
2006 

  

July 3, 
2005 

  

July 2, 
2006 

  

July 3, 
2005 

  

Share-based payment expense

$

$

$

15 

$

Tax benefit for share-based compensation expense

(2)

(1)

(5)

(1)

Share-based payment expense, net of tax

$

$

$

10 

$

Amounts capitalized as part of inventory cost were not significant. In the three months and six months ended July 2, 2006, theThe impact of modifications under the AtS productivity initiative to share-based awards was not significant and, in the three months and six months ended July 3, 2005, the impact of modifications under the Pharmacia restructuring program was not significant.any period presented above. Generally, these modifications resulted in an acceleration of vesting, either in accordance with plan terms or at management's discretion.

B.  Stock Options

Stock options, which entitle the holder to purchase, at the end of a vesting term, a specified number of shares of Pfizer common stock at a price per share set equal to the market price of Pfizer common stock on the date of grant, are accounted for at fair value at the date of grant in the income statement beginning in 2006. These fair values are generally amortized on an even basis over the vesting term into Cost of sales, Selling, informational and administrative expenses and Research and development expenses, as appropriate.

In 2005 and earlier years, stock options were accounted for under APB No. 25 using the intrinsic value method in the income statement and fair value information was disclosed. In these disclosures of fair value, we allocated stock option Share-based compensation expense based on the nominal vesting period, rather than the expected time to achieve retirement eligibility. Inassociated with Discontinued operations in 2006 we changed our method of allocating stock option compensation expense to a method based on the substantive vesting period for all new awards, while continuing to allocate outstanding nonvested awards not yet recognized as of December 31, 2005 under the nominal vesting period method. Specifically, under this prospective change in accounting policy, compensation expense related to stock options granted prior to 2006 that are subject to accelerated vesting upon retirement eligibility is being recognized over the vesting term of the grant, even though the service period after retirement eligibility is not considered to be a substantive vesting requirement. The impact of this change was not significant.

All employees may receive stock option grants. In virtually all instances, stock options vest after three years of continuous service from the grant date and have a contractual term of ten years; for certain members of management, vesting typically occurs in equal annual installments after three, four and five years from the grant date. In all cases, even for stock options that are subject to accelerated vesting upon voluntary retirement, stock options must be held for at least one year from grant date before any vesting may occur. In the event of a divestiture, options held by employees of the divested business are immediately vested and are exercisable from three months to their remaining term, depending on various conditions.

The fair value of each stock option grant is estimated on the grant date using the Black-Scholes-Merton option-pricing model, which incorporates a number of valuation assumptions noted in the following table, shown at their weighted-average values:

Three Months Ended

Six Months Ended

July 2,
2006

July 3,
2005

July 2,
2006

July 3,
2005

   

 

Expected dividend yield (a)

3.66%

  

2.72%

   

3.66%

   

2.90%

Risk-free interest rate (b)

4.59%

 

3.75%

4.59%

3.96%

Expected stock price volatility (c)

24.50%

 

16.90%

24.50%

21.93%

Expected term (d) (years)

6   

 

2.75   

6   

5.75   

(a)

Determined using a constant dividend yield during the expected term of the option.

(b)

Determined using the extrapolated yield on U.S. Treasury zero-coupon issues.

(c)

Determined using implied volatility, after consideration of historical volatility.

(d)

Determined using historical exercise and post-vesting termination patterns.

In the first quarter of 2006, we changed our method of estimating expected stock price volatility to reflect market-based inputs under emerging stock option valuation considerations. We use the implied volatility in a long-term traded option, after consideration of historical volatility. In 2005, we used an average term structure of volatility quoted to us by financial institutions, after consideration of historical volatility.

The following table summarizes all stock option activity during the six months ended July 2, 2006:

Shares (thousands)

Weighted-
Average
Exercise
Price
Per Share

Weighted-
Average
Remaining
Contractual
Term
(years)

Aggregate
Intrinsic
Value(a)
(millions)

Outstanding, January 1, 2006

627,404 

$33.51

Granted

68,699 

26.20

Exercised

(17,764)

15.52

Forfeited

(4,987)

31.37

Cancelled

(36,909)

32.43

Outstanding, July 2, 2006

636,443 

33.31

5.5

$286

Vested and expected to vest(b), July 2, 2006

627,736 

33.34

5.5

286

Exercisable, July 2, 2006

436,636 

34.50

4.1

286

(a)

Market price of underlying stock less exercise price.

(b)

The number of options expected to vest takes into account an estimate of expected forfeitures.

The following table provides data related to all stock option activity:

Three Months Ended

Six Months Ended

(millions of dollars, except per stock option amounts and years)

July 2,
2006

  

July 3,
2005

  

July 2,
2006

  

July 3,
2005

  

Weighted-average grant date fair value per stock option

$

5.42

$

3.23

$

5.42

$

5.15

Aggregate intrinsic value on exercise

$

66

$

210

$

171

$

296

Cash received upon exercise

$

109

$

160

$

267

$

262

Tax benefits realized related to exercise

$

20

$

80

$

53

$

103

Total compensation cost related to nonvested stock options not yet recognized, pre-tax(a)

$

567

N/A

$

567

N/A

Weighted-average period in years over which stock option compensation cost is expected to be recognized(b)

1.6

N/A

1.6

N/A

 

     

 

(a)

The total compensation cost related to our Consumer Healthcare business is $27 million.

 

(b)

The planned divestiture of our Consumer Healthcare business does not have a significant impact on this weighted-average period.

 

C.  Restricted Stock Units

RSUs, which entitle the holder to receive, at the end of a vesting term, a specified number of shares of Pfizer common stock, including shares resulting from dividend equivalents paid on such RSUs, are accounted for at fair value at the date of grant. Most RSUs vest in substantially equal portions each year over five years of continuous service; the fair value related to each year's portion is then amortized evenly into Cost of sales, Selling, informational and administrative expenses and Research and development expenses, as appropriate. For certain members of senior and key management, vesting may occur after three years of continuous service.

The fair value of each RSU grant is estimated on the grant date using the average price of Pfizer common stock on the date of grant.

The following table summarizes all RSU activity during the six months ended July 2, 2006:

(thousands of shares)

Shares 

   

Weighted-Average
Grant Date Fair
Value Per Share

    

Nonvested, January 1, 2006

12,803 

$26.89

Granted

12,682 

26.15

Vested

(3,300)

27.31

Reinvested dividend equivalents

307 

25.01

Forfeited

(782)

26.06

Nonvested, July 2, 2006

21,710 

26.36

The following table provides data related to all RSU activity:

Three Months Ended

Six Months Ended

(millions of dollars, except per RSU amounts and years)

July 2,
2006

  

July 3,
2005

  

July 2,
2006

  

July 3,
2005

  

Weighted-average grant date fair value per RSU

$

25.75

$

27.53

$

26.35

$

26.24

Total fair value of shares vested

$

1

$

1

$

90

$

1

Total compensation cost related to nonvested RSU awards not yet recognized, pre-tax(a)

$

388

N/A

$

388

N/A

Weighted-average period in years over which RSU cost is expected to be recognized(b)

4.3

N/A

4.3

N/A

 

       

 

(a)

The total compensation cost related to our Consumer Healthcare business is $20 million.

 

(b)

The planned divestiture of our Consumer Healthcare business does not have a significant impact on this weighted-average period.

 

D.  Performance Share Awards (PSAs) and Performance-Contingent Share Awards (PCSAs)

PSAs in 2006 and PCSAs prior to 2006 entitle the holder to receive, at the end of a vesting term, a number of shares of Pfizer common stock, within a specified range of shares, calculated using a non-discretionary formula that measures Pfizer's performance relative to an industry peer group. PSAs are accounted for at fair value at the date of grant in the income statement beginning with grants in 2006. Further, PSAs are generally amortized on an even basis over the vesting term into Cost of sales, Selling, informational and administrative expenses and Research and development expenses, as appropriate. For grants in 2005 and earlier years, PCSA grants are accounted for using the intrinsic value method in the income statement.

Senior and other key members of management may receive PSA and PCSA grants. In most instances, PSA grants vest after three years and PCSA grants vest after five years of continuous service from the grant date. In certain instances, PCSA grants vest over two to four years of continuous service from the grant date. The vesting terms are equal to the contractual terms.

The 2004 Plan limitations on the maximum amount of share-based awards apply to all awards including PCSA and PSA grants. In 2001, our shareholders approved the 2001 Performance-Contingent Share Award Plan (the 2001 Plan), allowing a maximum of 12.5 million shares to be awarded to all participants. This maximum was applied to awards for performance periods beginning after January 1, 2002 through 2004. The 2004 Plan is the only plan under which share-based awards may be granted in the future.

PSA grants made in 2006 will vest and be paid based on a non-discretionary formula that measures our performance using relative total shareholder return over a performance period relative to an industry peer group. If our minimum performance in the measure is below the threshold level relative to the peer group, then no shares will be paid. PCSA grants made prior to 2006 will vest and be paid based on a non-discretionary formula, which measures our performance using relative total shareholder return and relative change in diluted earnings per common share (EPS) over a performance period relative to an industry peer group. If our minimum performance in the measures is below the threshold level relative to the peer group, then no shares will be paid.

As of January 1, 2006, we measure PSA grants at fair value using the average price of Pfizer common stock on the date of grant times the target number of shares. The target number of shares is determined by reference to the fair value of share-based awards to similar employees in the industry peer group. We measure PCSA grants at intrinsic value whereby the probable award was allocated over the term of the award, then the resultant shares are adjusted to the fair value of our common stock at each accounting period until the date of payment.

The following table summarizes all PSA and PCSA activity during the six months ended July 2, 2006, with the shares granted representing the maximum award that could be achieved:

(thousands of shares)

Shares 

  

Weighted-Average
Grant Date
Value Per Share

   

Nonvested, January 1, 2006

13,366 

$23.32

Granted

1,539 

26.19

Vested

(1,583)

26.20

Forfeited(a)

(1,513)

26.20

Nonvested, July 2, 2006

11,809 

23.82

(a)

Forfeited includes 345 thousand shares that were forfeited by retirees. At the discretion of the Compensation Committee of the Company's Board of Directors, $9 million in cash was paid to such retirees, which amount was equivalent to the fair value of the forfeited shares pro rated for the portion of the performance period that was completed prior to retirement.

The following table provides data related to all PSA and PCSA activity:

Three Months Ended

Six Months Ended

(millions of dollars, except per PCSA amounts and years)

July 2,
2006

  

July 3,
2005

  

July 2,
2006

  

July 3,
2005

  

Weighted-average grant date intrinsic value per PCSA

$

23.47

$

27.10

$

23.47

$

27.10

Total intrinsic value of vested PCSA shares

$

--

$

--

$

50

$

56

Total compensation cost related to nonvested PSA grants not yet recognized, pre-tax(a)

$

17

N/A

$

17

N/A

Weighted-average period in years over which PSA cost is expected to be recognized(b)

2.5

N/A

2.5

N/A

   

(a)

The total compensation cost related to our Consumer Healthcare business is nominal.

 

(b)

The planned divestiture of our Consumer Healthcare business does not have a significant impact on this weighted-average period.

 

We entered into forward-purchase contracts that partially offset the potential impact on net income of our obligation under the pre-2006 PCSAs. At settlement date we will, at the option of the counterparty to each of the contracts, either receive our own stock or settle the contracts for cash. Other contract terms are as follows:

Per Share

Maximum
Maturity (years)

(thousands of shares)

Purchase
Price

  

July 2,
2006

  

Dec. 31,
2005

   

3,051

$33.85

0.4

--

3,051

33.84

--

0.4

The financial statements include the following items related to these contracts:

Prepaid expenses and taxes includes:

fair value of these contracts

Other (income)/deductions - net includes:

changes in the fair value of these contracts

E.  Restricted Stock

Restricted stock grants, which entitle the holder to receive, at the end of a vesting term, a specified number of shares of Pfizer common stock, and which also entitle the holder to receive dividends paid on such grants, are accounted for at fair value at the date of grant.

Senior and key members of management received restricted stock awards prior to 2005. In most instances, restricted stock grants vest after three years of continuous service from the grant date. The vesting terms are equal to the contractual terms.

These awards have not been significant.

F.  Transition Information

The following table shows the effect on results for the three months and six months ended July 3, 2005 as if we had applied the fair-value-based recognition provisions of SFAS 123R to measure stock-based compensation expense for the option grants:

(millions of dollars, except per common share data)

 

Three Months 
Ended 
July 3,2005 

 

Six Months 
Ended 
July 3,2005 

   

Net income available to common shareholders used in the calculation of basic earnings per common share:

As reported under GAAP(a)

$

3,461 

$

3,761 

Compensation expense - net of tax(b)

(104)

(252)

Pro forma

$

3,357 

$

3,509 

Basic earnings per common share:

As reported under GAAP(a)

$

0.47 

$

0.51 

Compensation expense - net of tax(b)

(0.01)

(0.04)

Pro forma

$

0.46 

$

0.47 

Net income available to common shareholders used in the calculation of diluted earnings per common share:

As reported under GAAP(a)

$

3,461 

$

3,761 

Compensation expense - net of tax(b)

(104)

(252)

Pro forma

$

3,357 

$

3,509 

Diluted earnings per common share:

As reported under GAAP(a)

$

0.47 

$

0.51 

Compensation expense - net of tax(b)

(0.02)

(0.04)

Pro forma

$

0.45 

$

0.47 

(a) 

Includes stock-based compensation expense, net of related tax effects, of $38 million and $53 million for the three months and six months ended July 3, 2005.

(b) 

Pro forma compensation expense related to stock options that are subject to accelerated vesting upon retirement is recognized over the period of employment up to the vesting date of the grant.

Note 15.13.  Earnings Per Common Share

Basic and diluted EPSearnings per common share (EPS) were computed using the following common share data:

Three Months Ended

Six Months Ended

Three Months Ended

Six Months Ended

(millions)

July 2,
2006

July 3,
2005

July 2,
2006 

July 3,
2005

July 1,
2007

July 2,
2006

July 1,
2007 

July 2,
2006 

EPS Numerator - Basic:

Income from continuing operations

$

2,290

$

3,375

$

6,296

$

3,531

$

1,345 

$

2,290

$

4,706 

$

6,296

Less: Preferred stock dividends - net of tax

2

2

3

2

2

3

Income available to common shareholders from continuing operations

2,288

3,373

6,293

3,529

1,344 

2,288

4,704 

6,293

Discontinued operations - net of tax

125

88

230

232

(78)

125

(47)

230

Net income available to common shareholders

$

2,413

$

3,461

$

6,523

$

3,761

$

1,266 

$

2,413

$

4,657 

$

6,523

EPS Denominator - Basic:

Weighted-average number of common shares outstanding

7,282

7,366

7,298

7,391

6,966 

7,282

7,009 

7,298

EPS Numerator - Diluted:

Income from continuing operations

$

2,290

$

3,375

$

6,296

$

3,531

$

1,345 

$

2,290

$

4,706 

$

6,296

Less: ESOP contribution - net of tax

1

2

2

2

-- 

1

2

Income available to common shareholders from continuing operations

2,289

3,373

6,294

3,529

1,345 

2,289

4,705 

6,294

Discontinued operations - net of tax

125

88

230

232

(78)

125

(47)

230

Net income available to common shareholders

$

2,414

$

3,461

$

6,524

$

3,761

$

1,267 

$

2,414

$

4,658 

$

6,524

EPS Denominator - Diluted:

Weighted-average number of common shares outstanding

7,282

7,366

7,298

7,391

6,966 

7,282

7,009 

7,298

Common share equivalents: stock options, restricted stock units, stock issuable under employee compensation plans and convertible preferred stock

23

52

32

54

24 

23

24 

32

Weighted-average number of common shares outstanding and common share equivalents

7,305

7,418

7,330

7,445

6,990 

7,305

7,033 

7,330

Stock options that had exercise prices greater than the average market price of our common stock and stock issuable under employee compensation plans*

403 

592 

404 

591 

*

These common stock equivalents were outstanding during these periods but were not included in the computation of diluted EPS for these periods because their inclusion would have had an anti-dilutive effect.

Outstanding stock options, representing about 592 million shares and 591 million shares of common stock during the three-month and six-month periods ended July 2, 2006 and about 513 million shares and 519 million shares of common stock during the three-month and six-month periods ended July 3, 2005, had exercise prices greater than the average market price of our common stock. These options were excluded fromIn the computation of diluted EPS, for these periods because their inclusion would have had an anti-dilutive effect.

Also, in the diluted computation, income from continuing operations and net income are reduced by the incremental contribution to the ESOPs, which were acquired as part of our Pharmacia acquisition. This contribution is the after-tax difference between the income that the ESOPs would have received in preferred stock dividends and the dividend on the common shares assumed to have been outstanding.

Note 16.14.  Segment Information

We operate in the following business segments:

Human Health

Pharmaceutical

The Pharmaceutical segment includes products that prevent and treat cardiovascular and metabolic diseases, central nervous system disorders, arthritis and pain, infectious and respiratory diseases, urogenital conditions, cancer, eye disease, endocrine disorders and allergies.

Animal Health

The Animal Health segment includes products that prevent and treat diseases in livestock and companion animals.

   

The Human Health segment, which represents our pharmaceutical business, includes treatments for cardiovascular and metabolic diseases, central nervous system disorders, arthritis and pain, infectious and respiratory diseases, urogenital conditions, cancer, eye disease, endocrine disorders and allergies. The Human Health segment also includes our contract manufacturing and bulk pharmaceutical chemicals business.

Animal Health

The Animal Health segment includes prevention and treatments for diseases in livestock and companion animals.

Segment profit/(loss) is measured based on income from continuing operations before provision for taxes on income and minority interests. Certain costs, such as significant impacts of purchase accounting for acquisitions, merger-relatedacquisition-related costs, and costs related to our AtS productivity initiative and transition activity associated with our former Consumer Healthcare business, are included in Corporate/Other only. This methodology is utilized by management to evaluate our businesses.

Revenues and profit/(loss) by segment for the three months and six months ended July 1, 2007, and July 2, 2006, and July 3, 2005, follow:

Three Months Ended

Six Months Ended

Three Months Ended

Six Months Ended

(millions of dollars)

July 2, 
2006 

July 3, 
2005 

  

July 2, 
2006 

  

July 3, 
2005 

July 1, 
2007 

July 2, 
2006 

  

July 1, 
2007 

  

July 2, 
2006 

Revenues:

Human Health

$

10,999 

$

10,723 

$

22,099 

$

22,236 

Pharmaceutical

$

10,105 

$

10,915 

$

21,686 

$

21,932 

Animal Health

583 

578 

1,094 

1,073 

632 

583 

1,218 

1,094 

Corporate/Other(a)

159 

151 

295 

286 

347 

243 

654 

462 

Total revenues

$

11,741 

$

11,452 

$

23,488 

$

23,595 

$

11,084 

$

11,741 

$

23,558 

$

23,488 

Segment profit/(loss)(b)

Human Health

$

5,046 

$

4,581 

$

10,794 

$

9,966 

Pharmaceutical

$

4,273 

$

5,262 

$

10,753 

$

11,216 

Animal Health

117 

123 

215 

203 

142 

125 

279 

234 

Corporate/Other(a)

(2,080)

(c)

(1,792)

(d)

(3,656)

(c)

(4,523)

(d)

(2,796)

(c)

(2,304)

(d)

(5,360)

(c)

(4,097)

(d)

Total profit/(loss)

$

3,083 

$

2,912 

$

7,353 

$

5,646 

$

1,619 

$

3,083 

$

5,672 

$

7,353 

  

(a)

Corporate/Other includes theour gelatin capsules business, our contract manufacturing of empty two-piece gelatin capsules.business and a bulk pharmaceutical chemicals business, and transition activity associated with our former Consumer Healthcare business (sold in December 2006). Corporate/Other also includes interest income/(expense), corporate expenses (e.g., corporate administration costs), other income/(expense) (e.g., realized gains and losses attributable to our investments in debt and equity securities), certain performance-based and all share-based compensation expenses, not allocated to the business segments, share-based payments, significant impacts of purchase accounting for acquisitions, certain milestone payments, merger-relatedacquisition-related costs, intangible asset impairments and costs related to our AtS productivity initiative.

  

(b)

Segment profit/(loss) equals income from continuing operations before provision for taxes on income and minority interests. Certain costs, such as significant impacts of purchase accounting for acquisitions, merger-relatedacquisition-related costs, and costs related to our AtS productivity initiative and transition activity associated with our former Consumer Healthcare business, are included in Corporate/Other only. This methodology is utilized by management to evaluate our businesses.

  

(c)

For the three months and six months ended July 1, 2007, Corporate/Other includes (i) significant impacts of purchase accounting for acquisitions of $782 million and $1.9 billion, including acquired in-process research and development, intangible asset amortization and other charges, (ii) acquisition-related costs of $16 million and $33 million, (iii) restructuring charges and implementation costs associated with the AtS productivity initiative of $1.4 billion and $2.3 billion, (iv) all share-based compensation expense, (v) transition activity associated with our former Consumer Healthcare business of $7 million income and $16 million income and (vi) a $25 million charge for litigation-related matters.

(d)

For the three months and six months ended July 2, 2006, Corporate/Other includes (i) significant impacts of purchase accounting for acquisitions of $1.3 billion and $2.1 billion, including acquired in-process research and development charges and incremental intangible asset amortization and other charges, (ii) merger-relatedacquisition-related costs of $6 million and $11 million, (iii) restructuring charges and implementation costs associated with the AtS productivity initiative of $442 million and $921 million, (iv) gain on disposals of investments and other of $23 million and $74 million, and (v) a research and development milestone due to us from sanofi-aventis of approximately $118 million in the first quarter of 2006.

(d)

For the three months and six months ended July 3, 2005, Corporate/Other includes (i) significant impacts of purchase accounting for acquisitions of $1.1 billion and $1.9 billion, including acquired in-process R&D charges, incremental intangible asset amortization and other charges, (ii) merger-related costs of $243 million and $459 million, (iii) costs associated with the suspension of Bextra's sales in the first quarter of 2005 of $1.2 billion, and (iv) restructuring charges and implementation costs associated with the AtS productivity initiative of $54 million in the second quarter of 2005.

Revenues for each group of similar products follow:

Three Months Ended

Six Months Ended

Three Months Ended

Six Months Ended

(millions of dollars)

July 2,
2006

July 3,
2005

  


Change 

  

July 2,
2006

July 3,
2005

  


Change 

July 1,
2007

July 2,
2006

  


Change 

  

July 1,
2007

July 2,
2006

  


Change 

HUMAN HEALTH

PHARMACEUTICAL

Cardiovascular and metabolic diseases

$

4,769

$

4,471

7%

$

9,517

$

9,197

3%

$

4,083

$

4,769

(14)%

$

9,238

$

9,517

(3)%

Central nervous system disorders

1,643

1,537

7   

3,287

3,129

5   

1,174

1,643

(29)   

2,419

3,287

(26)   

Arthritis and pain

627

549

14   

1,268

1,188

7   

626

627

--    

1,375

1,268

8    

Infectious and respiratory diseases

835

1,102

(24)  

1,772

2,585

(31)  

837

835

--    

1,750

1,772

(1)   

Urology

660

626

6   

1,323

1,328

--   

663

660

--    

1,414

1,323

7    

Oncology

540

513

5   

1,010

992

2   

652

540

21    

1,247

1,010

24    

Ophthalmology

352

341

3   

689

674

2   

400

352

14    

766

689

11    

Endocrine disorders

232

263

(12)  

478

521

(8)  

253

232

9    

498

478

4    

All other

1,017

1,073

(5)  

2,107

2,132

(1)  

1,025

933

10    

2,189

1,940

13    

Alliance revenue

324

248

31   

648

490

32   

392

324

21    

790

648

22    

Total Human Health

10,999

10,723

3   

22,099

22,236

(1)  

Total Pharmaceutical

10,105

10,915

(7)   

21,686

21,932

(1)   

ANIMAL HEALTH

583

578

1   

1,094

1,073

2   

632

583

9    

1,218

1,094

11    

OTHER

159

151

6   

295

286

4   

347

243

43    

654

462

42    

Total revenues

$

11,741

$

11,452

3   

$

23,488

$

23,595

--   

$

11,084

$

11,741

(6)   

$

23,558

$

23,488

--    

REVIEW REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Shareholders and Board of Directors of Pfizer Inc:

We have reviewed the condensed consolidated balance sheet of Pfizer Inc and Subsidiary Companies as of July 2, 2006,1, 2007, the related condensed consolidated statements of income for the three-month and six-monthsix month periods ended July 2, 20061, 2007 and July 3, 2005,2, 2006, and the related condensed consolidated statements of cash flows for the six-monthsix month periods ended July 2, 20061, 2007 and July 3, 2005.2, 2006. These condensed consolidated financial statements are the responsibility of the Company's management.

We conducted our reviews in accordance with the standards of the Public Company Accounting Oversight Board (United States). A review of interim financial information consists principally of applying analytical procedures and making inquiries of persons responsible for financial and accounting matters. It is substantially less in scope than an audit conducted in accordance with the standards of the Public Company Accounting Oversight Board (United States), the objective of which is the expression of an opinion regarding the financial statements taken as a whole. Accordingly, we do not express such an opinion.

Based on our reviews, we are not aware of any material modifications that should be made to the condensed consolidated financial statements referred to above for them to be in conformity with U.S. generally accepted accounting principles.

We have previously audited, in accordance with standards of the Public Company Accounting Oversight Board (United States), the consolidated balance sheet of Pfizer Inc and Subsidiary Companies as of December 31, 2005,2006, and the related consolidated statements of income, shareholders' equity, and cash flows for the year then ended (not presented herein); and in our report dated February 24, 2006,27, 2007, we expressed an unqualified opinion on those consolidated financial statements. In our opinion, the information set forth in the accompanying condensed consolidated balance sheet as of December 31, 2005,2006, is fairly stated, in all material respects, in relation to the consolidated balance sheet from which it has been derived.

KPMG LLP

New York, New York
August 11, 20066, 2007

Item 2.  Management's Discussion and Analysis of Financial Condition and Results of Operations (MD&A)

Introduction

Our MD&A is provided in addition to the accompanying condensed consolidated financial statements and footnotes to assist readers in understanding Pfizer's results of operations, financial condition and cash flows. The MD&A is organized as follows:

Overview of ConsolidatedOur Performance and Operating ResultsEnvironment. This section, beginning on page 26, provides a general description of Pfizer's business; discusses significant acquisitions made during the first six months of 2006, as well as the planned disposition of the Consumer Healthcare business;21, provides information about the following: our business; our performance during the three months and six months ended July 1, 2007; our operating environment; our response to key opportunities and summarizeschallenges; our strategic initiatives, such as acquisitions; and our productivity initiative.and cost savings program.

Revenues. This section, beginning on page 29,25, provides an analysis of our products and revenues for the three months and six months ended July 2, 20061, 2007, and July 3, 2005,2, 2006, as well as an overview of important product developments.

Costs and Expenses. This section, beginning on page 39,35, provides a discussion about our costs and expenses.

Provision/(Benefit)Provision for Taxes on Income. This section, beginning on page 40,37, provides a discussion of items impacting our tax provision for the periods presented.

Adjusted Income. This section, beginning on page 41,37, provides a discussion of an alternative view of performance used by management.

Financial Condition, Liquidity and Capital Resources. This section, beginning on page 45,42, provides an analysis of our balance sheets as of  July 2, 20061, 2007, and December 31, 2005,2006, and cash flows for the six months ended July 2, 20061, 2007, and  July 3, 2005,2, 2006, as well as a discussion of our outstanding debt and commitments that existed as of July 2, 20061, 2007, and December 31, 2005.2006. Included in the discussion of outstanding debt is a discussion of the amount of financial capacity available to help fund Pfizer's future commitments.activities.

   

Outlook.Outlook. This section, beginning on page 49,46, provides a discussion of forecasted financial performance.our expectations for full-year 2007 and 2008.

Forward-Looking Information and Factors That May Affect Future Results. This section, beginning on page 50,46, provides a description of the risks and uncertainties that could cause actual results to differ materially from those discussed in forward-looking statements set forth in this reportMD&A relating to theour financial results, operations and business prospects of the Company.plans and prospects. Such forward-looking statements are based on management's current expectations about future events, which are inherently susceptible to uncertainty and changes in circumstances. Also included in this section is a discussion of Legal Proceedings and Contingencies.

Components of the Condensed Consolidated Statement of Income follow:

Three Months Ended

Six Months Ended

Three Months Ended

Six Months Ended

(millions of dollars, except per common share data)

July 2, 
2006 

July 3, 
2005

% Change

July 2, 
2006 

July 3, 
2005 

% Change

July 1, 
2007 

July 2, 
2006 

% Change

July 1, 
2007 

July 2, 
2006 

% Change

Revenues

$

11,741 

$

11,452 

3%

$

23,488 

$

23,595

--%

$

11,084 

$

11,741 

(6)%

$

23,558 

$

23,488 

-- %

Cost of sales

1,790 

1,762 

2   

3,461 

3,639

(5)  

2,109 

1,790 

18    

3,996 

3,461 

15    

% of revenues

15.2 

%

15.4

%

14.7

%

15.4

%

19.0 

%

15.2 

%

17.0 

%

14.7 

%

Selling, informational and administrative expenses

3,881 

3,766 

3   

7,276 

7,431

(2)  

3,844 

3,881 

(1)   

7,205 

7,276 

(1)   

% of revenues

33.1

%

32.9

%

31.0

%

31.5

%

34.7 

%

33.1 

%

30.6 

%

31.0 

%

Research and development expenses

1,742 

1,830 

(5)  

3,285 

3,547

(7)  

2,165 

1,742 

24    

3,830 

3,285 

17    

% of revenues

14.8

%

16.0

%

14.0 

%

15.0

%

19.5 

%

14.8 

%

16.3 

%

14.0 

%

Amortization of intangible assets

823 

856 

(4)  

1,648 

1,736

(5)  

783 

823 

(5)   

1,598 

1,648 

(3)   

% of revenues

7.0

%

7.5

%

7.0

%

7.4

%

7.1 

%

7.0 

%

6.8 

%

7.0 

%

Merger-related in-process research and development charges

513 

260 

97   

513 

262

96   

Acquisition-related in-process research and development charges

-- 

513 

*    

283 

513 

(45)   

% of revenues

4.4

%

2.3

%

2.2

%

1.1

%

-- 

%

4.4 

%

1.2 

%

2.2 

%

Restructuring charges and merger-related costs

268 

264 

2   

567 

480

18   

Restructuring charges and acquisition-related costs

1,051 

268 

292    

1,863 

567 

229    

% of revenues

2.3

%

2.3

%

2.4

%

2.0

%

9.5 

%

2.3 

%

7.9 

%

2.4 

%

Other (income)/deductions - net

(359)

(198)

81   

(615)

854

(172)  

(487)

(359)

36    

(889)

(615)

45    

Income from continuing operations before provision/(benefit) for taxes on income, and minority interests

3,083 

2,912 

6   

7,353 

5,646

30   

Income from continuing operations before provision for taxes on income, and minority interests

1,619 

3,083 

(47)   

5,672 

7,353 

(23)   

% of revenues

26.3

%

25.4

%

31.3

%

23.9

%

14.6 

%

26.3 

%

24.1 

%

31.3 

%

Provision/(benefit) for taxes on income

790 

(464)

*   

1,052 

2,111

(50)  

Provision for taxes on income

272 

790 

(66)   

961 

1,052 

(9)   

Effective tax rate

25.6

%

(15.9)

%

14.3

%

37.4

%

16.8 

%

25.6 

%

16.9 

%

14.3 

%

Minority interests

154   

4

67   

(45)   

(15)   

Income from continuing operations

2,290 

3,375 

(32)  

6,296 

3,531

78   

1,345 

2,290 

(41)   

4,706 

6,296 

(25)   

% of revenues

19.5

%

29.5

%

26.8

%

15.0

%

12.1 

%

19.5 

%

20.0 

%

26.8 

%

Discontinued operations - net of tax

125 

88 

43   

230 

232

--   

(78)

125 

*    

(47)

230 

*    

Net income

$

2,415 

$

3,463 

(30)  

$

6,526 

$

3,763

73   

$

1,267 

$

2,415 

(48)   

$

4,659 

$

6,526 

(29)   

% of revenues

20.6

%

30.2

%

27.8

%

15.9

%

11.4 

%

20.6 

%

19.8 

%

27.8 

%

Earnings per common share - basic:

Income from continuing operations

$

0.31 

$

0.46 

(33)  

$

0.86 

$

0.48

79   

$

0.19 

$

0.31 

(39)   

$

0.67 

$

0.86 

(22)   

Discontinued operations - net of tax

0.02 

0.01 

100   

0.03 

0.03

--   

(0.01)

0.02 

*    

(0.01)

0.03 

*    

Net income

$

0.33 

$

0.47 

(30)  

$

0.89 

$

0.51

75   

$

0.18 

$

0.33 

(45)   

$

0.66 

$

0.89 

(26)   

Earnings per common share - diluted:

Income from continuing operations

$

0.31 

$

0.46 

(33)  

$

0.86 

$

0.48

79   

$

0.19 

$

0.31 

(39)   

$

0.67 

$

0.86 

(22)   

Discontinued operations - net of tax

0.02 

0.01 

100   

0.03 

0.03

--   

(0.01)

0.02 

*    

(0.01)

0.03 

*    

Net income

$

0.33 

$

0.47 

(30)  

$

0.89 

$

0.51

75   

$

0.18 

$

0.33 

(45)   

$

0.66 

$

0.89 

(26)   

Cash dividends paid per common share

$

0.24 

$

0.19 

$

0.48 

$

0.38

$

0.29 

$

0.24 

$

0.58 

$

0.48 

* Calculation not meaningful

OVERVIEW OF OUR CONSOLIDATEDPERFORMANCE AND OPERATING RESULTSENVIRONMENT

Our Business

We are a research-based, global, pharmaceuticalresearch-based company that discovers, develops, manufacturesis dedicated to better health and markets leading prescription medicinesgreater access to healthcare for humanspeople and their valued animals. Our longstandingpurpose is to help people live longer, healthier, happier and more productive lives. Our efforts in support of that purpose include the discovery, development, manufacture and marketing of breakthrough medicines; the exploration of ideas that advance the frontiers of science and medicine; and the support of programs dedicated to illness prevention, health and wellness, and increased access to quality healthcare. Our value proposition has beenis to provedemonstrate that our medicines can effectively treat disease, including the associated symptoms and suffering, and this remains our core mission. We have expanded our value proposition to also show that not only can our medicines treat disease, but that theyform the basis for an overall improvement in healthcare systems and their related costs. This improvement can also markedly improve health systemsbe achieved by reducing overall healthcare costs, improving societies' economic well-being and increasing effective prevention and treatment of disease. We generate revenue throughand by reducing the need for hospitalization. Our revenues are derived from the sale of our products, as well as through alliance agreements, by co-promotingunder which we co-promote products discovered by other companies.

Our 2007 Performance

AcquisitionsRevenues

An area where we are expanding aggressively is in biologics, large-molecule approaches to treating disease where small molecules are not available or effective. On May 16, 2006, we completed the acquisition of all of the outstanding shares of Rinat Neuroscience Corp., a biologics company with several new central-nervous-system product candidates. In connection with the acquisition, as part of our preliminary purchase price allocation, we recorded $478 million, pre-tax, in Merger-related in-process research and development charges.

On February 28, 2006, we completed the acquisition of the sanofi-aventis world-wide rights, including patent rights and production technology, to manufacture and sell Exubera, an inhaled form of insulin for use in adults with type 1 and type 2 diabetes, and the insulin-production business and facilities located in Frankfurt, Germany, previously jointly owned by Pfizer and sanofi-aventis, for approximately $1.4 billion (including transaction costs). In connection with the acquisition, as part of our preliminary purchase price allocation, we recorded an intangible asset for developed technology rights of approximately $1.0 billion, inventory valued at $218 million and goodwill of approximately $166 million, all of which have been allocated to our Human Health segment. The amortization of the developed technology rights will be primarily included in Cost of Sales. Given the size and complexity of the acquisition, the fair valuation and allocation work is still being finalized and is expected to be completed in the third quarter. To the extent that our estimates need to be adjusted, we will do so. Priorsecond quarter of  2007 decreased $657 million (6%), compared to the acquisition,same period in connection with our collaboration agreement with sanofi-aventis, we recorded a research and development milestone due to us from sanofi-aventis of approximately $118 million ($71 million, after tax)2006.Revenues in the first quartersix months of 2006 in Research and development expenses upon the approval of Exubera in January 2006 by the Food and Drug Administration (FDA).

Discontinued Operations

We evaluate our businesses and product lines periodically for strategic fit within our operations. We sold or are in the process of selling the following businesses that do not fit our strategic goals:

In June 2006, we entered into an agreement to sell our Consumer Healthcare business to Johnson & Johnson for approximately $16.6 billion in cash. This business comprises substantially all of our former Consumer Healthcare segment and other associated amounts, such as purchase-accounting impacts and merger-related costs, and restructuring and implementation costs related to our Adapting to Scale (AtS) productivity initiative, previously reported in the Corporate/Other segment. In addition, certain manufacturing facility assets and liabilities, which were previously part of our Human Health or Corporate/Other segment, are included in the planned sale of the Consumer Healthcare business. In connection with the decision to sell this business, for all periods presented, the operating results associated with this business that will be discontinued have been reclassified into Discontinued operations - net of tax in the condensed consolidated statements of income and the assets and liabilities associated with this business that will be sold have been reclassified into Assets/Liabilities of discontinued operations and other assets/liabilities held for sale, as appropriate, on the condensed consolidated balance sheets. The divestiture of the Consumer Healthcare business is expected to close in late 2006 and is subject to customary closing conditions, including receipt of regulatory approvals.

In the first quarter of 2005, we sold the second of three European generic pharmaceutical businesses which had been included in our Human Health segment for 70 million euros (approximately $93 million) and recorded a gain of $57 million ($36 million, net of tax) in Gains on sales of discontinued operations - net of tax in the condensed consolidated statement of income. In addition, we recorded an impairment charge of $9 million ($6 million, net of tax) related to the third European generic business in Income from discontinued operations - net of tax in the condensed consolidated statement of income for the six months ended July 3, 2005.

 Our Operating Environment

We are navigating a period of significant change for the Company. Aggressive cost-cutting efforts, coupled with investments in business development and significantly improved research and development (R&D) productivity, are preparing us to transition2007, were comparable to the next-generation Pfizer. Our strategy is to drive growthsame period in our in-line medicines and to invest in promising new medicines.

We have a broad presence in the healthcare industry, with important medicines in many major therapeutic areas. While we continue to look for the most innovative products to fill gaps in our portfolio, we also continue to face a challenging and dynamically changing environment in our pharmaceutical business. This includes the loss of exclusivity of major products, uncertainty concerning selective COX-2 inhibitor products, increasing regulatory scrutiny of drug safety, the adoption of new direct-to-consumer advertising guidelines and lower prescription growth rates and increased competition in certain therapeutic areas.

We believe that the strong aggregate performance of our in-line2006. The significant product portfolio and the potential of our new-product pipeline demonstrate our ability to generate new revenues. Our performance in 2006 has been, and will continue to be, substantially adversely impacted by loss of U.S. exclusivity of Neurontin, Diflucan and Accupril/Accuretic in 2004, Zithromax in November 2005 and Zoloft at the end of June 2006. In addition, we face a substantial adverse impactimpacts on our performance from the loss of U.S. exclusivity for Norvasc and Zyrtec during 2007 and Camptosar and Inspra in 2008. These nine products represented 31% of our Human Health revenues and 29% of our total revenues for the year ended December 31, 2005. In addition, some of our products face competition in the form of new branded products or generic drugs, which treat similar diseases or indications. Revenues in 2006 have also been,second quarter and may continue to be, impacted by uncertainty regarding selective COX-2 inhibitor products (see further discussion in the section "Human Health--Selected Product Descriptions"). Our total revenues increased 3% in the three months ended July 2, 2006 and were flat in thefirst six months ended July 2, 2006 asof 2007, compared to the same periods in 2006, are as follows:

Second Quarter

Six Months

Increase/

Increase/

(decrease)

% Change

(decrease)

% Change

(millions of dollars)

07/06

  

07/06

07/06

  

07/06

Zoloft(a)

$

(579)

(82)

$

(1,212)

(82)

Norvasc(a)

(516)

(45)

(630)

(27)

Lipitor(b)

(404)

(13)

(153)

(2)

Chantix/Champix(c)

200 

362 

Lyrica(c)

134 

49 

337 

73 

Sutent(c)

110 

311 

196 

380 

Caduet

39 

50 

108 

69 

Xalatan/Xalacom

38 

11 

61 

Zyvox

35 

21 

107 

30 

Vfend

27 

23 

58 

25 

Aromasin

17 

22 

40 

27 

Detrol/Detrol LA

14 

57 

11 

Geodon/Zeldox

13 

47 

14 

Celebrex

114 

12 

Alliance revenue

68 

21 

142 

22 

(a)

Zoloft and Norvasc are products that have lost U.S. exclusivity since 2006.

(b)

Lipitor  has been impacted by competitive pressures and other factors.

(c)

Chantix/Champix, Lyrica and Sutent are major new products that were launched since 2005.

*

Calculation not meaningful.

Partially offsetting theseRevenues benefited from favorable foreign exchange impacts of $284 million in the three monthssecond quarter of 2007 and $553 million in the first six months ended July 2,of 2007. Revenues also benefited from lower pharmaceutical product rebates in the first six months of 2007 of approximately $123 million, compared to the same period in 2006, primarily due to the Medicare Prescription Drug Improvement and Modernization Act of 2003 (the Medicare Act), effective as of January 1, 2006, changes in product mix and the impact of our contracting strategies with both government and non-government entities. The impact of rebates in the second quarter of 2007, compared to the second quarter of 2006, was the solid aggregate performancenot significant to overall revenues. (See further discussion in the balance"Revenues - Pharmaceutical Revenues" section of this MD&A.)

Income from continuing operations for the second quarter of 2007 was $1.3 billion compared to $2.3 billion in the second quarter of 2006 and $4.7 billion in the first six months of 2007 compared to $6.3 billion in the first six months of 2006. The decreases were primarily due to higher restructuring costs associated with our productivity initiatives in 2007, higher R&D expense, primarily due to the timing of our broad portfolio of patent-protected medicines. Our portfolio of medicines includes three of the world's 25 best-selling medicines,payments to Bristol-Myers Squibb Company (BMS) in connection with four medicines that lead their therapeutic areas. Our results reflect two underlying forces. First, Pfizer markets the broadest array of in-lineour collaboration to develop and recently launched products in the industry; and second, Pfizer is a business going through a process of transformation. We are addressing the loss of exclusivity of a number of products by advancing a number of internally developed, in-licensed and co-promoted product candidates. So far this year, we have launched three new medicines in the U.S.--Sutent, Eraxis and Chantix, and initial supplies of Exubera will be available in the U.S. in September 2006. In June 2006, we received an approvable letter from the FDA for Zeven (dalbavancin) and now expect approval and launch in 2007. In June 2006, after certain decisions by the FDA, we notified Neurocrine Biosciences, Inc. (Neurocrine) that we are returning the development and marketing rights for indiplon to Neurocrine.

We believe we have important competitive advantages that will serve us well and distinguish us from others in our industry. Our product portfolio and pipeline demonstrate the benefits of Pfizer's scale and our skill at leveraging the opportunities it provides us. Scale also enhances our status as 'partner of choice' with other companies who have promising product candidates and technologies,commercialize apixaban, as well as giving us influence asthe decline in product revenues discussed above, including the impact of product mix in revenues on Cost of sales and the absence of one-time tax benefits occurring in 2006, partially offset by the decline in Acquisition-related in-process research and development charges from 2006. (See further discussion in the "Cost and Expenses" and "Provision for Taxes on Income" sections of this MD&A.)

Discontinued Operations - net of tax, primarily related to our former Consumer Healthcare business, which was sold in December 2006, for the second quarter of 2007, was a global purchaser$78 million loss compared to $125 million in income in the second quarter of goods2006 and services. Wea $47 million loss in the first six months of 2007 compared to $230 million in income in the first six months of 2006. For a period of time, we will continue to build ongenerate cash flows and enhanceto report income statement activity in continuing operations that are associated with our Research & Development capabilities through acquisitionsformer Consumer Healthcare business. The activities that give rise to these impacts are transitional in nature and collaborations. Through targeted acquisitions, licensing opportunitiesgenerally result from agreements that ensure and internal development,facilitate the orderly transfer of business operations to the new owner. Included in continuing operations for the second quarter of 2007, are the following amounts associated with these transition service agreements that will no longer occur after the full transfer of activities to the new owner: Revenues of $50 million, Cost of sales of $45 million, Selling, informational and administrative expense of $5 million and Other (income)/deduction-net of $7 million in income, and for the first six months of 2007, are: Revenues of $94 million, Cost of sales of $80 million, Selling, informational and administrative expense of $7 million and Other (income)/deduction-net of $9 million in income. (See Notes to Condensed Consolidated Financial Statements-Note 4.Discontinued Operations.)

In the first quarter of 2007, we are augmenting our commercial portfolio. acquired Embrex, Inc. and BioRexis Pharmaceutical Corp. (See further discussion in the "Our Strategic Initiatives - Strategy and Recent Transactions: Acquisitions, Licensing and Collaborations" section of this MD&A.)

We have also made progress with our Adapting to Scale (AtS) productivity initiative, which is a broad-based, company-wide effort to leverage our scale and strength more robustly and increase our productivity. (See further discussion in the "Our Productivity and Cost Savings Program" section "Adaptingof this MD&A.) (For an understanding of Adjusted income, see the "Adjusted Income" section of this MD&A.)

Our Operating Environment

We and our industry continue to Scaleface significant challenges in a profoundly changing business environment, as explained more fully in Pfizer's Annual Report on Form 10-K for the year ended December 31, 2006. Such industry-wide factors, including pricing and access, intellectual property rights, product competition, the regulatory environment, pipeline productivity and the changing business environment, can significantly impact our businesses. We are taking steps to change the way we run our businesses.

Generic competition significantly impacts our business. We lost U.S. exclusivity for Zoloft in June 2006 and Norvasc in March 2007 and, as expected, significant revenue declines followed. Lipitor began to face competition in the U.S. from generic pravastatin (Pravachol) in April 2006 and generic simvastatin (Zocor) in June 2006, in addition to other competitive pressures. While we anticipated the difficulty posed by these generic competitors, in the U.S., the volume of patients who switched from Lipitor to generic simvastatin following the entry of multiple generics was greater than we had predicted, particularly in the managed-care environment. In the second quarter of 2007, we improved Lipitor's switch rate volume, returning towards pre-multisource generic levels. In Canada, a lower-court decision against Pfizer has created uncertainty regarding Lipitor's patent protection in Canada. We have appealed that decision. In addition to these challenges, we face the loss of U.S. exclusivity for Zyrtec later in 2007 and Camptosar in 2008. (For more detailed information about Lipitor, Norvasc, Zoloft and other significant products, see further discussion in the "Revenues - - Pharmaceutical - Selected Product Descriptions" section of this MD&A.)

We will continue to aggressively defend our patent rights against increasingly aggressive infringement whenever appropriate.

(See Part II, Other Information; Item 1, Legal Proceedings, of this Form 10-Q for a discussion of certain recent developments with respect to patent litigation.)

These and other industry-wide factors that may affect our business should be considered along with the information presented in the "Forward-Looking Information and Factors that May Affect Future Results" section of this MD&A.

Response to Key Opportunities and Challenges

As announced on January 22, 2007, we are committed to changing the way we run our business in order to meet the challenges of the changing business environment and to take advantage of the diverse opportunities in the market place.

Our five immediate priorities are to:

Maximize our near-and long-term revenues;

Establish a lower and more flexible cost base;

Create smaller, more focused and more accountable operating units;

Engage more productively with customers, patients, physicians and other collaborators; and 

Make Pfizer a great place to work.

We believe that we are making progress on all of these goals. For details about our strategic initiatives, see "Our Strategic Initiatives - Strategy and Recent Transactions" section of this MD&A, and for details about our productivity initiative, see "Our Productivity Initiative and Merger-Related Synergies.Cost Savings Program" section of this MD&A.

We are examining a whole range of possibilities that will shape the company over the next five to 10 years. Some of the strategic elements that build on our immediate priorities while providing a framework for our longer-term opportunities may include:

Revitalizing our internal Research & Development (R&D) productivity byfocusing our efforts to improve productivity and give discovery and development teams more flexibility and clearer goals, as well as committing considerable resources to promising therapeutic areas including oncology, diabetes, and neurological disorders, among others.

Focusing our business development by thoroughly assessing and prioritizing every therapeutic area, looking at gaps we have identified and accelerating programs we already have. We are also developing opportunistic strategies concerning the best products, product candidates and technologies.

Building a major presence in biotherapeutics by recognizing that our core strength with small molecules must be complemented by large molecules, as they involve some of the most promising R&D technology and cutting-edge science in medical research, as well as integrating our investments, R&D and existing internal capabilities with disciplined business development.

Driving innovation in product life cycle management by taking a broader look at our business model and examining it from all angles. We believe there are opportunities to better manage our products' growth and development throughout their entire time on the market and bring innovation to our "go to market" promotional and commercial strategies. We plan to develop ways to further enhance the value of mature products, as well as those close to losing their exclusivity and to create product-line extensions where feasible. In connection with the production of these products, we are pursuing new ways to accelerate our high-quality, low-cost manufacturing initiatives.

Stepping up our focus and investments in emerging markets by developing strategies in areas, especially Eastern Europe and Asia, where changing demographics and economics will drive growing demand for high-quality healthcare and offer the best potential for our products.

Seeking complementary opportunities in products and technologies that have the potential to add value to our core pharmaceutical offerings as there are many possible ways for us to enhance our pharmaceutical products with the medical technologies of the future.

Our Strategic Initiatives - Strategy and Recent Transactions

")Acquisitions, Licensing and Collaborations

AdaptingWe are committed to Scalecapitalizing on new growth opportunities by advancing our own new-product pipeline, as well as through opportunistic licensing, co-promotion agreements and acquisitions. Our business development strategy targets a number of growth opportunities, including biologics, oncology, Alzheimer's disease, cardiovascular disease, vaccines and other products and services that seek to provide innovative healthcare solutions.

In the second quarter of 2007, we entered into a collaboration agreement with BMS to further develop and commercialize apixaban, an oral anticoagulant compound discovered by BMS, that is being studied for the prevention and treatment of a broad range of venous and arterial thrombotic conditions. We made an up-front payment to BMS of $250 million and additional payments to BMS related to product development efforts, which are included in Research and development expenses for the three months and six months ended July 1, 2007. We may also make additional payments of up to $750 million to BMS based on development and regulatory milestones. In a separate agreement, we will also collaborate with BMS on the research, development and commercialization of a Pfizer discovery program, which includes preclinical compounds with potential applications for the treatment of metabolic disorders, including obesity and diabetes.

In April 2007, we agreed with OSI Pharmaceuticals, Inc. (OSI) to terminate a 2002 collaboration agreement to co-promote Macugen, for the treatment of age-related macular degeneration, in the U.S. We also agreed to amend and restate a 2002 license agreement for Macugen, and to return to OSI all rights to develop and commercialize Macugen in the U.S. In return, OSI granted us an exclusive right to develop and commercialize Macugen in the rest of the world.

In the first quarter of 2007, we acquired BioRexis Pharmaceutical Corp., a privately held biopharmaceutical company with a number of diabetes candidates and a novel technology platform for developing new protein drug candidates, and Embrex, Inc., an animal health company that possesses a unique vaccine delivery system known as Inovoject, which enables baby chicks to be vaccinated while inside their eggs. In connection with these and other small acquisitions, we recorded $283 million in Acquisition-related in-process research and development charges.

In the second quarter of 2006, we completed the acquisition of Rinat Neuroscience Corp. (Rinat), a biologics company with several new central-nervous-system product candidates. In connection with this and other smaller acquisitions, we recorded $513 million in Acquisition-related in-process research and development charges in the second quarter of 2006.

In February 2006, we completed the acquisition of the sanofi-aventis worldwide rights, including patent rights and production technology, to manufacture and sell Exubera, an inhaled form of insulin for use in adults with type 1 and type 2 diabetes, and the insulin-production business and facilities located in Frankfurt, Germany, previously jointly owned by Pfizer and sanofi-aventis, for approximately $1.4 billion in cash (including transaction costs). In connection with the acquisition, as part of our final purchase price allocation, we recorded $1.0 billion of developed technology rights, $218 million of inventory and $166 million of Goodwill, all of which have been allocated to our Pharmaceutical segment. The amortization of the developed technology rights is primarily included in Cost of sales. Prior to the acquisition, in connection with our collaboration agreement with sanofi-aventis, we recorded a research and development milestone due to us from sanofi-aventis of approximately $118 million ($71 million, after tax) in the first quarter of 2006 in Research and development expenses upon the approval of Exubera in January 2006 by the Food and Drug Administration (FDA).

Our Productivity Initiative and Merger-Related SynergiesCost Savings Program

During 2005 and the first six months of 2006, weWe have made significant progress with our multi-year productivity initiative, called Adapting to Scale (AtS), which is designed to increase efficiency and streamline decision-making across the Company.company. This initiative was launched in early 2005 follows the integration of Warner-Lambert and Pharmacia Corporation (Pharmacia), which resultedbroadened in the tripling of Pfizer's revenues over the past six years. The integration of those two companies resulted in a combined annual expense reduction of approximately $6 billion.October 2006.

We continue to expect thatare generating cost savings from our AtS productivity initiative will bethrough site rationalization in excess of $2 billion in 2006, growing to about $4 billion annually upon completion in 2008, notwithstanding the planned divestiture of our Consumer Healthcare businessresearch and the expensemanufacturing, reductions associated with that business. These savings are expected to be realized in procurement, operating expenses and facilities, among other sources. Savings realized during the second quarter and first six months of 2006 total approximately $500 million and $1 billion. We plan to use the cost savings we generate, in part, to fund key investments, including new product launches and the development of the many promising new medicines in our pipeline. The Company expects that the aggregate cost of implementing this initiative through 2008 will be approximately $4 billion to $5 billion on a pre-tax basis.

global sales force, streamlined organizational structures, staff function reductions, and increased outsourcing and procurement savings. Projects in various stages of implementationcompletion include:

Reorganizing Pfizer Global Research & Development (PGRD)Reorganization of our Field Force - We completed the U.S. reorganization in December 2006, which included a 20% reduction in our U.S. field force. We are taking similar measures in the international markets. The restructured U.S. field force was operational starting in April 2007 and productivity per sales representative has returned to increase efficiencythe levels before the reorganization, retaining our competitiveness and effectiveness in bringing new therapies to patients-in-need while reducing the costshare of researchvoice. Globally, we have reduced our overall workforce by approximately 8% so far this year. Additional savings are being generated from de-layering, eliminating duplicative work, and development. PGRD has been reorganized into eleven therapeutic areas: cardiovascular, metabolic, and endocrine; central nervous system; inflammation; allergy and respiratory; infectious diseases; pain; gastrointestinal and hepatitis; oncology; urology and sexual health; ophthalmology; and dermatology. Discovery Research will retain its existing structure of six drug-candidate discovery sites. Development will move toward single sites for most therapeutic areas.strategically re-aligning various functions.

   

Continuing our optimizationStrategic Outsourcing - As an example of Pfizer's network of plants,this activity, we recently partnered with a single strategic service provider for certain information technology activities which began with the acquisition of Pharmacia, to ensure that the Company's manufacturing facilities are aligned with current and future product needs. We have focused on innovation and delivering value through a simplified supply network. During 2005 and through the first six months of 2006, 18 sites were identified for rationalization (Angers and Val de Reuil, France; Arecibo and Cruce Davila, Puerto Rico; Augusta, Georgia; Bangkok, Thailand; Corby and Morpeth, U.K.; Groton, Connecticut; Holland, Michigan; Jakarta, Indonesia; Seoul, Korea; Orangeville, Canada; Parsippany, New Jersey; Tlalpan, Mexico; Tsukuba, Japan; and Stockholm and Uppsala-Fyrislund, Sweden). In addition, there have been extensive consolidationsperformed by Pfizer and realignments of operations resulting in streamlined operationscontractors. By consolidating 11 third-party providers and staff reductions. In particular, Sandwich, U.K.; Lincolnreducing labor cost, we expect to generate considerable annual savings and Omaha, Nebraska sites; Puerto Rico sites; Lititz, Pennsylvania; and Brooklyn, N.Y. have undergone notable staff reductions.higher quality services.

   

RealigningPlant Network Optimization - We are transforming our European marketing teams and implementing initiatives designedglobal manufacturing network to improve the effectivenessefficiency and reduce overall cost. We have reduced our network of plants to 60 from 93 four years ago. We have also announced significant additional closures and divestitures. The cumulative impact will be a more focused, streamlined and competitive manufacturing operation, with less than 50% of our field force in Japan. During 2005,plants and a reduction of 35% of our manufacturing employees compared to 2003. Further, we completedcurrently outsource the manufacture of approximately 17% of our products on a major reorganization of the U.S. field force, reshaping the management structurecost basis and plan to be more responsive to commercial trends as the Medicare Modernization Act takes effect and driving greater sales-force accountability in preparation for the launch of new medicines.increase this substantially by 2010.

  

PursuingEnhanced R&D Productivity - We are actively balancing the actions required to achieve our cost savings in information technology resulting from significant reductions in application software (already significantly reduced from over 8,000 applications at the timetargets with those required to promote enhanced R&D productivity. In January 2007, we announced plans to close five R&D sites as part of our efforts to rationalize our facilities footprint. To date, approximately two-thirds of the Pharmacia acquisitionportfolio projects that are moving between sites have been transferred and are in 2003)their new sites. The remainder of the early-stage portfolio projects will be transferred by the end of the third quarter of 2007; and data centers (tothe late-stage project transfers will be reduced from 17 to 4), as well as rationalizationcomplete by the end of service providers, while enhancing our ability to invest2007, with minimal interruption in innovative technology opportunities to further propel our growth.

Reducing costs in purchased goods and services. Purchasing initiatives are focusing on rationalizing suppliers, leveraging the approximately $16 billionprogress of goods and services that Pfizer purchases annually and improving demand management to optimize levels of outside services needed and strategic sourcing from lower-cost sources. For example, savings from demand management are being derived in part from reductions in travel, entertainment, consulting and other external service expenses. Facilities savings are being found in site rationalization, energy conservation and renegotiated service contracts.development.

In 2008, at current exchange rates (rates approximating foreign currency spot rates at the end of our second quarter for international operations-May 2007), we continue to expect to achieve an absolute net reduction of the pre-tax total expense component of Adjusted income of at least $1.5 billion and $2.0 billion, compared to 2006. (For an understanding of Adjusted income, see the "Adjusted Income" section of this MD&A.)

REVENUES

Worldwide revenues by segment and geographic area for the three monthssecond quarter and first six months ended July 2,of 2007 and 2006 and July 3, 2005 follow:

Three Months Ended

Three Months Ended

% Change in Revenues

Worldwide

U.S.

International

% Change in Revenues

Worldwide

U.S.

International

World-

Inter-

July 2,

July 3,

July 2,

July 2,

July 2,

July 3,

Worldwide

U.S.

International

July 1,

July 2,

July 1,

July 2,

July 1,

July 2,

wide

U.S.

national

(millions of dollars)

2006

2005

2006

2005

2006

2005

06/05

06/05

06/05

2007

2006

2007

2006

2007

2006

07/06

07/06

07/06

Human Health

$

10,999

$

10,723

$

5,781

$

5,419

$

5,218

$

5,304

3

7

(2)

Pharmaceutical

$

10,105

$

10,915

$

4,467

$

5,756

$

5,638

$

5,159

(7)

(22)

9

Animal Health

583

578

262

263

321

315

1

--

632

583

254

262

378

321

(3)

18

Other

159

151

51

46

108

105

6

9

347

243

120

75

227

168

43 

60 

35

Total Revenues

$

11,741

$

11,452

$

6,094

$

5,728

$

5,647

(a)

$

5,724

(a)

3

6

(1)

$

11,084

$

11,741

$

4,841

$

6,093

$

6,243

(a)

$

5,648

(a)

(6)

(21)

11

   

(a)

Includes revenuerevenues from Japan of $852$833 million (7.3%(7.5% of total revenues) and $877$852 million (7.7%(7.3% of total revenues) for the three months ended July 2, 20061, 2007, and July 3, 2005.2, 2006.

  

Six Months Ended

Six Months Ended

% Change in Revenues

Worldwide

U.S.

International

% Change in Revenues

Worldwide

U.S.

International

World-

Inter-

July 2,

July 3,

July 2,

July 2,

July 2,

July 3,

Worldwide

U.S.

International

July 1,

July 2,

July 1,

July 2,

July 1,

July 2,

wide

U.S.

national

(millions of dollars)

2006

2005

2006

2005

2006

2005

06/05

06/05

06/05

2007

2006

2007

2006

2007

2006

07/06

07/06

07/06

Human Health

$

22,099

$

22,236

$

12,121

$

11,656

$

9,978

$

10,580

(1)

4

(6)

Pharmaceutical

$

21,686

$

21,932

$

10,935

$

12,068

$

10,751

$

9,864

(1)

(9)

9

Animal Health

1,094

1,073

491

482

603

591

2

1,218

1,094

518

491

700

603

11 

16

Other

295

286

98

90

197

196

9

654

462

238

151

416

311

42 

58 

34

Total Revenues

$

23,488

$

23,595

$

12,710

$

12,228

$

10,778

(b)

$

11,367

(b)

-- 

4

(5)

$

23,558

$

23,488

$

11,691

$

12,710

$

11,867

(b)

$

10,778

(b)

-- 

(8)

10

   

(b)

Includes revenuerevenues from Japan of $1.6 billion (6.7% of total revenues) and $1.7 billion (7.4%for both of total revenues) for the six monthsmonth periods ended July 2, 20061, 2007, and July 3, 2005.2, 2006.

Human HealthPharmaceutical Revenues

Pfizer's Human Health business continued to show solid performance in many of our products, although revenue declines from loss of exclusivity on major products and other challenges tempered our growth in the three months ended July 2, 2006 and more than offset that performance for the six months ended July 2, 2006, as shown in the following table:

Human Health Revenues

 

(millions of dollars, except % growth)

Three
Months
Ended July 2,
2006

  

Impact on
Total 
Human Health 
06/05 
% Growth 

Six Months
Ended July 2,
2006

  

Impact on 
Total 
Human Health 
 06/05 
% Growth 

   

In-Line Products(a) and New Products(b)

$

9,827 

%

$

$19,596

%

Loss-of-exclusivity products and Bextra(c)

1,172 

(3)

2,503

(5)

Total Human Health revenues

$

10,999 

%

$

$22,099

 

(1)

%

(a)

In-Line Products is defined as worldwideWorldwide pharmaceutical revenues for the three months and six months ended July 2, 2006 of all Human Health products other than those referred to in notes (b) and (c).

(b)

New Products is defined as worldwide revenues for the three months and six months ended July 2, 2006 of products launched since the beginning of 2004--Caduet, Eraxis, Exubera, Inspra, Lyrica, Macugen, Olmetec, Onsenal, Revatio, Sutent and Zmax.

(c)

Loss-of-Exclusivity Products and Bextra is defined as worldwide revenues for the three months and six months ended July 2, 2006 of products that have lost U.S. exclusivity since the beginning of 2004--Accupril/Accuretic, Diflucan, Neurontin, Zithromax and Zoloft--and of Bextra, sales of which were suspended in 2005.

Total Human Health revenues increased 3% in the second quarter of 2007 were $10.1 billion, a decrease of 7% compared to the second quarter of 2006, and for the first six months of 2007 were down$21.7 billion, a decrease of 1% incompared to the first six months of 2006, as compared to the same periods in 2005,due primarily due to:

a decrease in revenues for Norvasc of $516 million in the second quarter of 2007 and $630 million in the first six months of 2007, primarily due to the loss of U.S. exclusivity in the first quarter of 2007;

a continued decrease in revenues for Zoloft, primarily due to the loss of U.S. exclusivity in June 2006, of $579 million in the second quarter of 2007 and $1.2 billion in the first six months of 2007; and

lower sales of Lipitor in the U.S., primarily resulting from competitive pressures from generics and in the second quarter of 2007, modest reductions in the dollar value of U.S. wholesaler inventory levels (as wholesalers adjusted their inventories to reflect the decrease in prescription levels), and increased rebates (reflecting our more flexible contracting strategy), among other factors,

partially offset by:

the solid aggregate performance of many products in our broad portfolio of patent-protected medicines;

   

an aggregate year-over-year increase in revenues from new products launched in the U.S. since 2005 of approximately $481 million in the second quarter of 2007 and within$962 million in the first six months of 2007; and

a decrease in rebates in the first six months of 2007 in both our government and non-government contracted businesses in the U.S., reflecting the continued impact of the Medicare Act, effective January 1, 2006, changes in our product mix and the impact of our contracting strategies.

Pharmaceutical revenues were also impacted by the weakening of the U.S. dollar relative to many foreign currencies, especially the euro and U.K. pound, which increased revenues by $252 million in the second quarter of 2007 and $497 million in the first six months of 2007.

Geographically:

in the U.S., Pharmaceutical revenues decreased 22% in the second quarter of 2007, compared to the second quarter of 2006, and 9% in the first six months of 2007, compared to the first six months of 2006, primarily due to the effect of approximately $294 millionthe loss of exclusivity for the second quarterZoloft and Norvasc, and lower sales of 2006 and $507 million for the first six months of 2006;Lipitor; and

   

an increase in our international markets, Pharmaceutical revenues due to price changes of about 3.7% and 3.6%increased 9% in both the second quarter and the first six months of 2006;

partially offset2007, compared to the same periods in 2006, primarily due to the favorable impact of foreign exchange on international revenues of $252 million (4.9%) in the second quarter of 20062007 and more than offset$497 million (5.0%) in the first six months of 2006 by:

a decrease2007, revenues from our new products, as well as growth in revenue from the loss of U.S. exclusivity of Zithromax in November 2005 of $260 million for the second quarter of 2006 and $807 million for the first six months of 2006;

the continued decline in revenue by $61 million for the second quarter of 2006 and $179 million for the first six months of 2006 of Neurontin, Diflucan and Accupril/Accuretic, which lost U.S. exclusivity in 2004;

the strengthening of the U.S. dollar relative to many foreign currencies, especially the euro, which decreased revenue by $195 million for the second quarter of 2006 and $534 million for the first six months of 2006; and

lower revenue for Zoloft, which has lost exclusivity in many European markets, by $90 million for the second quarter of 2006 and $156 million for the first six months of 2006.Celebrex sales.

The three months and

During the second quarter of 2007, international Pharmaceutical revenues grew to represent 55.8% of total Pharmaceutical revenues, compared to 47.3% in the second quarter of 2006. For the first six months ended July 2, 2006 were also impacted by increased competition and the overall market decline, as branded prescriptionsof 2007, international Pharmaceutical revenues represent 50% of total Pharmaceutical revenues, compared to 45% of total Pharmaceutical revenues in the U.S. declined 2% and 3% compared to the three months andfirst six months ended July 3, 2005.

Geographically:

of 2006. These increases have been fueled by the favorable impact of foreign exchange and higher volumes, despite pricing pressures in the U.S., Human Health revenues increased 7% and 4% in the three months and six months ended July 2, 2006 compared to the same periods in 2005 primarily due to revenues from new products and growth in Lipitor and Celebrex sales, partially offset by the loss of exclusivity of Zithromax in November 2005; and

in our international markets, Human Health revenues declined in the three months and six months ended July 2, 2006 compared to the same periods in 2005 by 2% and 6%, primarily due to the unfavorable impact of foreign exchange of $195 million (all of the decline) and $534 million (5 percentage points of the decline) and lower revenues of Zoloft due to the loss of exclusivity in many key international markets.

As is typical in the pharmaceutical industry, our gross product sales are subject to a variety of deductions, primarily representing rebates and discounts to government agencies, wholesalers and managed care organizations, with respect to our pharmaceutical products. These deductions represent estimates of the related obligations and, as such, judgment is required when estimating the impact of these sales deductions on gross sales for a reporting period. Historically, our adjustments to actual have not been material; onmaterial to our overall business. On a quarterly basis, theyour adjustments to actual generally have been less than 1% of Human HealthPharmaceutical net sales and can result in either a net increase or a net decrease to income. Product-specific rebate charges, however, can have a significant impact on year-over-year product growth trends. The rebate adjustments to actual for Lipitor unfavorably impacted revenues for Lipitor during the second quarter of 2007, while in the second quarter of 2006, the rebate adjustments to actual favorably impacted revenues for Lipitor. The inverse relationship between the rebate adjustments contributed to the decline in Lipitor revenues in the second quarter of 2007, compared to the same period in 2006.

Rebates under Medicaid and related state programs reduced revenues by $86 million in the second quarter of 2007 compared to $169 million in the second quarter of 2006 and $251 million in the first six months of 2007, compared to $374 million in the three months andfirst six months ended July 2, 2006 and $324 million and $699 million in the three months and six months ended July 3, 2005.of 2006. The decreasedecreases in Medicaid and related state program rebates isare due primarily to the impact of the Medicare Prescription Drug Improvement and Modernization Act, of 2003 (the Medicare Act), effective January 1, 2006, and changes in product mix, such as lower sales of Zithromax, Zoloft and Norvasc, all of which lost exclusivity in the U.S.

Rebates under Medicare reduced revenues by $153 million in the second quarter of 2007 compared to $91 million in the second quarter of 2006 and $200 million in the first six months of 2007 compared to $183 million in the first six months of 2006. The increases in Medicare rebates are due primarily to the impact of the Medicare Act, effective January 1, 2006, partially offset by changes in product mix, such as lower sales of Zithromax, Zoloft and Norvasc, all of which lost exclusivity in the U.S.

Performance-based contract rebates reduced revenues by $391 million in the second quarter of 2007 compared to $368 million in the second quarter of 2006 and $849 million in the first six months of 2007, compared to $911 million in the three months andfirst six months ended July 2, 2006 and $573 million and $1.2 billion in the three months and six months ended July 3, 2005.of 2006. The decrease in performance-based contract rebates is due primarily to the expirationwere impacted by lower sales of our contract with Express Scripts Inc. on December 31, 2005Zithromax, Zoloft and reduced managed care rebates related to Zithromax,Norvasc, all of which lost exclusivity in the U.S in November 2005.U.S., and the impact of our contracting strategies, primarily related to Lipitor. These contracts are with managed care customers, including health maintenance organizations and pharmacy benefit managers, who receive rebates based on the achievement of contracted performance terms for products. Rebates are product-specific and, therefore, for any given year are impacted by the mix of products sold.

Chargebacks (primarily discountsreimbursements to U.S. federal government agencies)wholesalers for honoring contracted prices to third parties) reduced revenues by $317 million in the second quarter of 2007 compared to $335 million in the second quarter of 2006 and $690 million in the first six months of 2007, compared to $688 million in the three months andfirst six months ended July 2, 2006 and $298 million and $592 millionof 2006. Chargebacks were impacted by the launch of certain generic products, including amlodipine besylate after Norvasc lost U.S. exclusivity in the three months and six months ended July 3, 2005.March 2007.

Our accruals for Medicaid rebates, Medicare rebates, contract rebates and chargebacks totaled $1.6$1.2 billion as of July 2, 2006,1, 2007, a decrease from $1.8$1.5 billion as of December 31, 20052006, due primarily to the impact of the Medicare Act.Act, changes in product mix and the impact of our contracting strategies.

Human Health--SelectedPharmaceutical--Selected Product Revenues

Revenue information for several of our major Human Healthpharmaceutical products follow:follows:

Three Months Ended

Six Months Ended

(millions of dollars)
Product

Primary Indications

July 2, 
2006 

  

% Change
from 2005

  

July 2, 
2006 

  

% Change
from 2005

Cardiovascular and
metabolic diseases:

Lipitor

Reduction of LDL cholesterol

$3,123 

9%

$6,230 

5%

Norvasc

Hypertension

1,158 

--   

2,341

--   

Cardura

Hypertension/Benign prostatic hyperplasia

139 

(10)  

265 

(14)  

Caduet

Reduction of LDL cholesterol and hypertension

80 

92   

157 

116   

Accupril/Accuretic

Hypertension/Congestive heart failure

69 

(6)  

137 

(21)  

Central nervous
system disorders:

Zoloft

Depression and certain anxiety disorders

706 

(11)  

1,485 

(9)  

Lyrica

Epilepsy, post-herpetic neuralgia and diabetic peripheral neuropathy

271 

606   

463 

693   

Geodon/Zeldox

Schizophrenia and acute manic or mixed episodes associated with bipolar disorder

165 

14   

347 

23   

Neurontin

Epilepsy and post-herpetic neuralgia

123 

(23)  

250 

(27)  

Aricept(a)

Alzheimer's disease

88 

3   

170 

--   

Xanax/Xanax XR

Anxiety/Panic disorders

79 

(24)  

161 

(22)  

Relpax

Migraine headaches

67 

35   

133 

29   

Arthritis and pain:

Celebrex

Arthritis pain and inflammation, acute pain

471 

17   

962 

18   

Infectious and
respiratory diseases:

Zyvox

Bacterial infections

167 

9   

353 

19   

Zithromax/Zmax

Bacterial infections

166 

(61)  

425 

(65)  

Vfend

Fungal infections

118 

30   

235 

32   

Diflucan

Fungal infections

110 

(14)  

217 

(19)  

Urology:

Viagra

Erectile dysfunction

394 

1   

784 

(5)  

Detrol/Detrol LA

Overactive bladder

255 

15   

515 

9   

Oncology:

Camptosar

Metastatic colorectal cancer

238 

2   

450 

1   

Ellence

Breast cancer

86 

(11)  

159 

(15)  

Aromasin

Breast cancer

75 

31   

145 

29   

Sutent

Metastatic renal cell carcinoma (mRCC) and malignant gastrointestinal stromal tumors (GIST)

36 

*   

52 

*   

Ophthalmology:

Xalatan/Xalacom

Glaucoma and ocular hypertension

351 

3   

688 

2   

Endocrine disorders:

Genotropin

Replacement of human growth hormone

191 

(5)  

388 

(4)  

All other:

Zyrtec/Zyrtec-D

Allergies

377 

6   

798 

15   

Alliance revenue:

Aricept, Macugen, Mirapex, Olmetec, Rebif and Spiriva

Alzheimer's disease (Aricept), neovascular (wet) age-related macular degeneration (Macugen), Parkinson's disease (Mirapex), hypertension (Olmetec), multiple sclerosis (Rebif), chronic obstructive pulmonary disease (Spiriva)

324 

31   

648 

32   

Three Months Ended

Six Months Ended

(millions of dollars)
Product

Primary Indications

July 1, 2007

%
Change
from
2006

July 1, 
2007 

%
Change
from
2006

Cardiovascular and
metabolic diseases:

Lipitor

Reduction of LDL cholesterol

$2,719 

(13)%

$6,077 

(2)%

Norvasc

Hypertension

642 

(45)   

1,711 

(27)   

Chantix/Champix

An aid to smoking cessation

200 

*   

362 

*    

Caduet

Reduction of LDL cholesterol and hypertension

119 

50    

265 

69    

Cardura

Hypertension/Benign prostatic hyperplasia

125 

(10)   

259 

(2)   

Central nervous
system disorders:

Lyrica

Epilepsy, post-herpetic neuralgia and diabetic peripheral neuropathy, fibromyalgia

405 

49    

800 

73    

Geodon/Zeldox

Schizophrenia and acute manic or mixed episodes associated with bipolar disorder

178 

8    

394 

14    

Zoloft

Depression and certain anxiety disorders

127 

(82)   

273 

(82)   

Neurontin

Epilepsy and post-herpetic neuralgia

105 

(15)   

215 

(14)   

Aricept(a)

Alzheimer's disease

100 

13    

185 

8   

Xanax/Xanax XR

Anxiety/Panic disorders

79 

1    

154 

(4)   

Relpax

Migraine headaches

66 

(2)   

149 

12    

Arthritis and pain:

Celebrex

Arthritis pain and inflammation, acute pain

478 

1    

1,076 

12    

Infectious and
respiratory diseases:

Zyvox

Bacterial infections

202 

21    

460 

30    

Vfend

Fungal infections

145 

23    

293 

25    

Zithromax/Zmax

Bacterial infections

108 

(35)   

239 

(44)   

Diflucan

Fungal infections

104 

(6)   

215 

(1)   

Urology:

Viagra

Erectile dysfunction

382 

(3)   

816 

4    

Detrol/Detrol LA

Overactive bladder

269 

5    

572 

11    

Oncology:

Camptosar

Metastatic colorectal cancer

241 

1    

470 

4    

Sutent

Advanced and/or metastatic renal cell carcinoma (mRCC) and refractory gastrointestinal stromal tumors (GIST)

146 

311    

248 

380    

Aromasin

Breast cancer

92 

22    

185 

27    

Ophthalmology:

Xalatan/Xalacom

Glaucoma and ocular hypertension

389 

11    

749 

9    

Endocrine disorders:

Genotropin

Replacement of human growth hormone

202 

6    

403 

4    

All other:

Zyrtec/Zyrtec-D

Allergies

385 

2    

846 

6    

Alliance revenues:

Aricept, Exforge, Macugen, Mirapex, Olmetec, Rebif and Spiriva

Alzheimer's disease (Aricept), neovascular (wet) age-related macular degeneration (Macugen), Parkinson's disease (Mirapex), hypertension (Exforge and Olmetec), multiple sclerosis (Rebif), chronic obstructive pulmonary disease (Spiriva)

392 

21    

790 

22    

(a)

 Represents direct sales under license agreement with Eisai Co., Ltd.

*

 Calculation not meaningful.

Certain amounts and percentages may reflect rounding adjustments.

Human Health--SelectedPharmaceutical --Selected Product Descriptions:

Lipitor, for the treatment of elevated cholesterolLDL-cholesterol levels in the blood, is the most widely used treatment for lowering cholesterol and the best-selling pharmaceutical product of any kind in the world, reaching over $6.2with $2.7 billion in worldwide salesrevenues in the second quarter of 2007, a decrease of 13% compared to the same period in 2006, and $6.1 billion in worldwide revenues in the first six months of 2006, an increase2007, a decrease of 5%2% compared to the same period in 2005.2006. In the U.S., salesrevenues of $3.8$1.4 billion represent growthin the second quarter of 7% over2007 declined 25% compared to the previous year's first six months. Internationally, Lipitor salessame period in 2006 and in the first six months of 2006 increased 3%2007, revenues of $3.5 billion declined 8% compared to the same period in 2005.2006. Internationally, Lipitor revenues in the second quarter of 2007 increased 5% and in the first six months of 2007 increased 6% compared to the same periods in 2006, primarily due to the favorable impact of foreign exchange.

   

The decline in Lipitor began to face competitionrevenues is driven by a combination of factors. The decline in the U.S.second quarter of 2007 from generic pravastatin (Pravachol) in Aprilthe comparable 2006 and generic simvastatin (Zocor) in June 2006 as well as other competitive pressures. In April 2006, we launched a new advertising campaign for Lipitor that highlights its strong benefit profile and advantageous formulary positioning. Scientific data continue to reinforce the trend toward the use of higher dosages of statins for greater cholesterol reduction.period resulted from:

   

New clinical findings continue to demonstrate

the benefitimpact of Lipitor on a wide range of endpoints, helping to support its differentiation versus thean intensely competitive statin market with competition and maintain its rank as the world's top-selling medicine. Recently, data from the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) clinical trial in stroke prevention were presented at the European Stroke Congress in Brussels and published in The New England Journal of Medicine.  SPARCL assessed treatment with Lipitor 80 mg compared to placebogeneric products, which resulted in a populationdecrease in prescription levels in the U.S. and an increased number of patients who have had a prior stroke but did not have coronary heart disease.  SPARCL is the first major study designed to evaluate this patient population.  In the trial, Lipitor was shown to significantly reduce the risk of an additional stroke by 16% and major coronary events such as heart attack, cardiac death or resuscitated cardiac arrest, by 35% compared to placebo.  An analysis of the SPARCL data was designed and conducted after the study ended to explore the types of strokes, ischemic or hemorrhagic, that occurred among patients in the study.  The vast majorityU.S. who switched from Lipitor to generic simvastatin following the entry of strokes in this trial were ischemic whilemultiple generics. In the number who experienced hemorrhagic was very small.  Patients taking Lipitor experienced a 22% reduction insecond quarter of 2007, we improved Lipitor's switch rate volume, returning towards pre-multisource generic levels, and have implemented comprehensive plans to address Lipitor's market position, including physician and patient initiatives aimed at reducing the riskrate of ischemic stroke. There were more patients in the Lipitor group who experienced hemorrhagic stroke (2.3%) comparedswitches to patients taking placebo (1.4%).  There was no difference in the number of deaths from hemorrhagic stroke between the two treatment groups.  The SPARCL findings represent important information for physicians and patients as up to one in five Americans who survive a first stroke will have another stroke within five years, according to data from the National Stroke Association. generics;

   

In addition, based on evolving clinical evidence, including landmark Lipitor studies (Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT_LLA),  Treating to New Targets (TNT) and  IDEAL),

increased payer pressure in the American Heart Association and the American College of Cardiology now state that it is reasonable to bring LDL-cholesterol levels to below 70 mg/dL for very high-risk patients, levels that Lipitor has been proven to achieve within a favorable safety profile along with providing incremental cardiovascular benefits for patients.  In addition, a pre-specified pharmacoeconomic analysis of the IDEAL study showed that one out of every six heart attacks, strokes, or cardiovascular procedures could be avoided for heart-disease patients treated with intensive Lipitor therapy (80 mg) instead of standard doses of Zocor (20-40 mg). U.S.;

   

In May

increased rebates associated with our more flexible U.S. contracting strategy, among other rebate factors. (For an understanding of rebates, see the "Pharmaceutical Revenue" section of this MD&A.); and

a modest reduction in the dollar value of U.S. wholesaler inventory levels, as wholesalers adjusted their inventories to reflect the decrease in prescription levels, 

partially offset by:

growth in the statin market in the U. S.; and

the favorable impact of foreign exchange.

The decline in Lipitor revenues in the first six months of 2007 from the comparable period in 2006 resulted from:

the European Commission approved Lipitor forimpact of an intensely competitive statin market with competition from both generic and branded products, which resulted in a decrease in prescription levels in the prevention of cardiovascular events such as heart attacksU.S.; and strokes in patients who are at a higher risk for experiencing a first cardiovascular event and have other risk factors such as diabetes or high blood pressure.  This label change, based on data from ASCOT-LLA clinical trials and Collaborative Atorvastatin Diabetes Study, is already in effect

increased payer pressure in the U.S.,

partially offset by:

a positive U.S. pricing impact, net of rebates, notwithstanding a more flexible contracting strategy; and

the favorable impact of foreign exchange.

On May 30, 2007, we announced the return of Lipitor to Express Scripts Inc.'s preferred list of drugs as of June 1, 2007, following our rebate agreement. We expect that the impact of this agreement will be seen in the second half of 2007.

On March 5, 2007, Lipitor was approved by the FDA for five new indications in patients with clinically evident heart disease, thereby expanding the U.S. label from primary prevention in moderate-risk patients to include secondary prevention in high-risk patients. Lipitor is now the only cholesterol-lowering medicine approved for the reduction in risk of hospitalization due to heart failure. These new indications have been incorporated into promotional materials, including a new direct-to-consumer (DTC) advertising campaign, and support the incremental benefit and overall safety of using higher doses of Lipitor.

Patents protecting Lipitor in Canada U.K.,are being challenged by various generic companies. One of those companies has been successful at the lower-court level, and France and will impact 12 European Union (E.U.) markets.we have appealed that decision, which we believe was wrongly decided. Lipitor sales in Canada would be adversely affected by generic competition if the Canadian courts or regulatory authorities allow generic competition in Canada before the expiration of our Lipitor patents.

   

See Part II, Other Information; Item 1, Legal Proceedings, of this Form 10-Q for a discussion of recent developments with respect to certain patent litigation relating to Lipitor.

   

Norvasc is the world's most-prescribed branded medicine, for treating hypertension. Norvasc maintainshypertension, lost exclusivity in many major markets globally, including the U.S., Japan, Canada and Australia, but in March 2007, six months earlier than expected, due to an appellate court decision that was counter to three previous trial court rulings in Pfizer's favor. Norvasc has also experienced patent expirations in many E.U. countries.countries but maintains exclusivity in certain other  major markets, including Japan and Canada. Norvasc salesworldwide revenues in the first six months of 2006 were even with those in2007 decreased 27% from the same period in 2005. See Part II, Other Information; Item 1, Legal Proceedings, of this Form 10-Q for a discussion of certain recent patent litigation relating to Norvasc.

Exubera, the first ever inhaled human insulin therapy for glycemic control received approvals from both the FDA and the European Commission for the treatment of adults with type 1 and type 2 diabetes in January 2006. Millions of people with diabetes are not achieving or maintaining acceptable blood sugar levels, despite the availability of current therapies.  Exubera meets a critical medical need by offering a highly effective and needle-free alternative to diabetes pills and insulin injections to manage this complicated, debilitating disease. Exubera was launched in Germany and Ireland in May 2006. In the U.S., a comprehensive physician and patient education and training program began on July 24, 2006, and is being rolled out in phases. The manufacturing process for Exubera is extremely complex and we are continuing to build inventory while working at production capacity at the Exubera manufacturing facilities. Initial supplies of Exubera will be available across the U.S. beginning in September 2006. See Part II, Other Information; Item 1, Legal Proceedings, of this Form 10-Q for a discussion of certain recent patent litigation relating to Exubera.Norvasc.

   

Caduet, a single pill therapy combining Norvasc and Lipitor, recorded worldwide revenues of $265 million, an increase of 69% for the first six months of 2007, compared to the same period in 2006. This was largely driven by a more focused message platform and a highly targeted consumer campaign in the U.S. Caduet was launched in the U.S. in May 2004 and continues to grow at significantly higher rates than the overall U.S. cardiovascular market. However, with the introduction of generic amlodipine besylate, in addition to increased competition, growth over the next several quarters may be impacted. During the first six months of 2007, Caduet was launched in France, Australia and Taiwan. We now expect Caduet to launch in Spain in late 2008.

Chantix/Champix, the first new prescription treatment to aid smoking cessation in nearly a decade, became available to patients in the U.S. in August 2006, in select E.U. markets in December 2006 and in Canada in April 2007. Chantix/Champix continues to demonstrate strong uptake, with nearly 2.5 million U.S. patients having filled a prescription as of June 15, 2007, representing slightly more than 5% of adult smokers in the U.S. In the U.S., an unbranded advertising campaign introduced earlier in 2007 is working to effectively develop the market, and branded advertising is planned for the third quarter of 2007. We continue to focus on increasing adherence and have introduced tools to physicians that provide data behind the benefit of a full 12-week course of therapy. In addition, we are conducting several pilot programs to reach patients in their first month of therapy through pharmacy programs, as well as through our GetQuit behavior modification program. Champix has secured final approval from the National Institute for Health and Clinical Excellence (NICE) for use in the state-funded National Health Service in the U.K., following a positive appraisal decision in May 2007. Our strategy for this innovative medicine is to build a sustainable, medically supported market over time and to seek to secure reimbursement--initiatives that we believe will drive future growth. Chantix/Champix recorded worldwide revenues of $362 million in the first six months of 2007.

Zoloft, which has lost exclusivity in the U.S. in June 2006 and earlier in many European markets, experienced a 9%an 82% worldwide revenue decline in the first six months of 20062007, compared to the same period in 2005. It is the most-prescribed antidepressant in the U.S.2006. It is indicated for the treatment of major depressive disorder, panic disorder, obsessive-compulsive disorder (OCD) in adults and children, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD) and social anxiety disorder (SAD). Zoloft is approved for acute and long-term use in all of these indications, with the exception of PMDD. It is the only approved agent for the long-term treatment of PTSD and SAD, an important differentiating feature as these disorders tend to be chronic. Zoloft lost exclusivity in the U.S. at the end of June 2006. Zoloft was approvedlaunched in Japan in AprilJuly 2006 for the indications of depression/depressed state and panic disorder.

Geodon/Zeldox, a psychotropic agent, is a dopamine and serotonin receptor antagonist indicated for the treatment of schizophrenia and acute manic or mixed episodes associated with bipolar disorder. It is available in both an oral capsule and rapid-acting intramuscular formulation. In the U.S., Geodon hit an all-time new prescription share weekly high of 7.3% during June 2006 and is the second-fastest-growing atypical anti-psychotic medication. In the first six months of 2006, total Geodon worldwide sales grew 23% compared to the same period in 2005.

Geodon growth is due to the better understanding by clinicians of its efficacy, increased benefits from optimal dosing, and its favorable metabolic profile, as confirmed by the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) trial. The CATIE schizophrenia study, supported by the National Institute of Mental Health and published in the New England Journal of Medicine, confirms that Geodon is an effective anti-psychotic and is less likely to worsen weight, lipids, and glucose metabolism than other agents. In fact, Geodon was associated with some improvement in these metabolic parameters. These findings are noteworthy because of the higher prevalence of metabolic issues among patients with schizophrenia and are consistent with previous Pfizer-sponsored clinical trials involving Geodon.

 

The U.S. Patent and Trademark Office granted a five-year extension to the Geodon U.S. patent, extending its exclusivity to 2012.

   

On May 2, 2007, the FDA proposed that the existing blackbox warning on the labels of all antidepressants, including Zoloft, which describes an increased risk of suicidal thoughts and behavior in some children and adolescents, be expanded to include young adults to age 24, particularly during the first two months of treatment. The proposed label change also states that studies have not shown this increased risk in adults older than 24, that adults age 65 and older who are treated with antidepressants have a decreased risk of suicidal thoughts and behavior, and that depression and certain other psychiatric disorders are themselves the most important causes of suicide. We have implemented this label change in accordance with the FDA's proposal.

Geodon/Zeldox, a psychotropic agent, is a dopamine and serotonin receptor antagonist indicated for the treatment of schizophrenia and acute manic or mixed episodes associated with bipolar disorder. It is available in both an oral capsule and rapid-acting intramuscular formulation. In the U.S., Geodon had a new prescription share of 6.8% for June 2007. In the first six months of 2007, Geodon worldwide revenues grew 14%, compared to the same period in 2006. Geodon growth was driven by recognition of its efficacy by prescribers as clinical experience increased, and by a favorable metabolic profile.

Exubera, the first inhaled human insulin therapy for glycemic control, received approvals from both the FDA and the European Commission for the treatment of adults with type 1 and type 2 diabetes in early 2006. Exubera represents a medical advance that offers patients a novel method of introducing insulin into their systems through the lungs. We continue to be disappointed with its slow acceptance. Since May 2006, Exubera has been launched in Germany, Ireland, the U.K. and in the U.S. Initial supplies of Exubera were available across the U.S. beginning in September 2006. We have found that this product requires more physician time and more patient-physician interaction than most products and that more extensive market-development activities are necessary. In response, in April 2007, we began supporting Exubera with a sales force that has greater cardiovascular-related experience. We have also trained a number of diabetes educators, who are now working in doctors' offices, and with nurses, engaging in clinical discussions to deliver the practical clinical guidance needed by physicians to help them understand the benefits of this innovative insulin-delivery system, as well as how to use Exubera. These resources are in direct response to our customers' need for increased support in using a novel delivery device. In addition, in the U.S. we began branded direct-to-consumer (DTC) advertising in print ads in mid-June 2007 and television ads in July 2007. We will continue to monitor the market acceptance of Exubera, while we seek to effectively establish this important product and serve the millions of diabetics whose blood sugar is still uncontrolled on current therapy.

Lyricaachieved $463$800 million in worldwide revenuerevenues in the first six months of 2006. It2007, an increase of 73% over the same period in 2006, continuing its performance as one of Pfizer's most successful pharmaceutical launches. In September 2006, Lyrica was approved by the European Commission onto treat central nerve pain, which is associated with conditions such as spinal injury, stroke and multiple sclerosis. In addition, in March 27, 2006, it was approved by the European Commission to treat generalized anxiety disorder (GAD) in adults, thereby providing a new treatment option for the approximately 1220 million Europeans living with GAD.

Lyrica was approved by the FDA in June 2005 for adjunctive therapy for adults with partial onset seizures. This indication built on the earlier FDA approval of Lyrica for two of the most common forms of neuropathic pain--diabetic peripheral neuropathy, a chronic neurologic condition affecting about three million Americans, and post-herpetic neuralgia. Lyrica was launched in the U.S., Canada, and Italy in September 2005 and is now approved in more than 60 countries and is currently available in more than 30 markets. More than 1 million patients have now been prescribed Lyrica since its introduction. Lyrica has already gained a 9.8%10.4% new prescription share of the total U.S. anti-epileptic market in June 2006, continuing its performance2007. Lyrica growth continues to be fueled by strong efficacy, as well as high physician and patient satisfaction. In June 2007, Lyrica was approved in the U.S. for the management of fibromyalgia, one of Pfizer'sthe most successful pharmaceutical launches.

Celebrex and Bextra

Celebrex achieved an 18% increase in worldwide sales incommon chronic, widespread pain conditions. This approval represents a breakthrough for the firstmore than six months of 2006 compared to the same period in 2005. In the first half of 2006, Celebrex delivered two consecutive quarters of double-digit sales growth and reached a monthly new prescription share high of 11.1% in June 2006. Strong clinical data continue to support Celebrex as an important medicine for patients with arthritis. The SUCCESS-1 study (Successive Celecoxib Efficacy and Safety Study), recently published in the American Journal of Medicine, showed that people with osteoarthritismillion Americans who take Celebrex experience significantly fewer gastrointestinal problems than patientssuffer from this debilitating condition who take non-specific non-steroidal anti-inflammatory drugs (NSAIDs).previously had no FDA-approved treatment.

   

Pfizer began to reintroduce branded advertisingCelebrex achieved a 1% increase in worldwide revenues in the U.S.second quarter of 2007 and a 12% increase in April 2006 in alignment with our new Direct-to-Consumer (DTC) advertising principles, highlighting Celebrex's strong clinical profile and benefits. In July 2005, the FDA approved a sixth indication for Celebrex--ankylosing spondylitis--a form of spinal arthritis that affects more than one million peopleworldwide revenues in the first six months of 2007, compared to the same periods in 2006. In the U.S., Celebrex had a monthly new prescription share of 10.6% in June 2007. In the U.S. revenues declined 4% in the second quarter of 2007 compared to the same period in 2006, driven by a modest decline in volume.

   

In 2005,January 2007, Celebrex was approved in accordance with decisions by applicable regulatory authorities,Japan for the treatment of osteoarthritis and rheumatoid arthritis. In February 2007, Celebrex was approved in Europe for the treatment of ankylosing spondylitis. In April 2007, we implemented label changes forlaunched an innovative Celebrex DTC television advertising campaign in the U.S. to re-initiate a productive patient-physician dialogue about treatment options for arthritis. The 2½-minute television advertisement opens by addressing cardiovascular (CV) safety first and clarifies misperceptions among arthritis sufferers about the E.U.,risks and we suspended sales of Bextra in the U.S., E.U., Canada and many other countries. The revised U.S. label for Celebrex contains a boxed warning of potential serious cardiovascular and gastrointestinal risks that is consistent with warnings for all other prescription NSAIDS. The revised E.U. label for Celebrex and all other COX-2 medicines includes a restriction on use by patients with established heart disease or stroke and additional warnings to physicians regarding use by patients with cardiovascular risk factors. Pfizer is continuing to conduct additional clinical studies evaluating the benefits and risks of Celebrex. Pfizer is supporting Cleveland Clinic's 20,000-patient prospective study to definitively evaluate the relative safety of Celebrex and two older pain medicationsother prescription non-steroidal anti-inflammatory drugs. This DTC ad campaign is helping to stimulate patient interest and initiate a productive dialogue between physicians and patients. The number of weekly visits to the Celebrex website has doubled and the number of calls to the patient 800 number has increased since the introduction of the ad. Future growth in patients with heart disease or at high riskdemand for Celebrex depends in part on the impact of heart disease.DTC advertising, as well as continued successful execution of the "CV first" strategy by the new and refocused U.S. sales force.

ZithromaxZithromax/Zmax experienced a 66%44% decline in worldwide salesrevenues in the first six months of 20062007 compared to the same period of 2005,2006, reflecting the expiration of itsZithromax's composition-of-matter patent in the U.S. in November 2005 and the end of Pfizer's active sales promotion in July 2005. During the fourth quarter of 2005, four generic versions of oral solid azithromycin were launched, including one authorized generic by Pfizer's Greenstone subsidiary. Through the first six months of 2006, generic azithromycin constituted 97.6% of the total oral solid azithromycin adult prescription volume.

Eraxis, an antifungal approved to treat candidemia and other forms of Candida infections (intra-abdominal abscesses and peritonitis), as well as esophageal candidiasis, was launched mid-June 2006 in the U.S. Candidemia is the most deadly of the common hospital-acquired bloodstream infections with a mortality rate of approximately 40%.

Viagra remains the leading treatment for erectile dysfunction and one of the world's most recognized pharmaceutical brands, with more than 58.9%53.5% of U.S. total prescriptions in the erectile dysfunction market through June 2006.2007. Viagra sales declined 5% worldwide inrevenues grew 4% worldwide--with U.S. revenues declining 2% and international revenues increasing 10%--in the first six months of 20062007, compared to the same period in 2005. We expect2006. The growth in Viagra international revenues was driven by foreign exchange, as well as a combination of other factors, including a focus on strengthening its value proposition to see continued pressure on saleskey customers and growth in the erectile dysfunction market. In July 2007, we launched a television ad campaign in the U.S. More than 45 states have either eliminated erectile-dysfunction coverage or have enacted "Preferred Drug Lists" that have the potential to limit Pfizer sales to state Medicaid programs,for Viagra aimed at educating and Medicare coverage will end in 2007. Effective January 1, 2006, federal funds may not be used for reimbursement of erectile-dysfunction medications by the Medicaid program.

Pfizer has introduced new branded and unbranded advertising to encouragemotivating men with erectile dysfunction to talk to their physicians about their condition and specifically about Viagra.

Sutent isa breakthrough oral multi-targeted tyrosine kinase inhibitor that combines anti-angiogenic and anti-tumor activity to simultaneously inhibit the blood supply to tumors and directly attack tumor cells.  Sutent wasapproved by the FDA in January 2006 for metastatic renal cell carcinoma (mRCC) and gastrointestinal stromal tumors (GIST) and has recorded $52 million in sales worldwide in the first half of 2006. In the five months following approval, Sutent has been prescribed to more than 6,000 patients. Sutent has received accelerated regulatory reviews and earlier-than-anticipated approvals or registration in several countries in Asia and Latin America and is expected to launch in many more markets worldwide over the coming months. On July 27, 2006, Sutent received conditional marketing authorization for both the mRCC and GIST indications in Europe from the European Commission. The conditional approval process is designed to get treatments with favorable benefit/risk profiles for life-threatening indications to target patient populations earlier; final approval is contingent on the provision of additional supportive information. This is the first time the European Commission has approved a new oncology drug under the conditional approval process.seek treatment.

   

Detrol/Detrol LA, a muscarinic receptor antagonist, is the most prescribed medicine worldwide for overactive bladder, a condition that affects up to 100 million people around the world. Detrol/Detrol LA is an extended-release formulation taken once daily. Worldwide Detrol/Detrol LA revenues grew 11% to $572 million in the first six months of 2007. Detrol/Detrol LA continues to lead the overactive bladder market and perform well in an increasingly competitive marketplace. In the U.S., Detrol/Detrol LA's new prescription share declined 3.4% to a 40.2% share for the first six months of 2007.

Camptosaris indicated as first-line therapy for metastatic colorectal cancer in combination with 5-fluorouracil and leucovorin. It is also indicated as second-line therapy for patients in whom metastatic colorectal cancer has recurred or progressed despite following initial fluorouracil-based therapy. Camptosar is for intravenous use only. RevenueWorldwide revenues in the first six months of 20062007 increased 1%4% to $450$470 million, compared to the same period in 2005. Among current oncology medications, the2006. The National Comprehensive Cancer Network (NCCN), an alliance of 1921 of the world's leading cancer centers, has issued guidelines recommending Camptosar as an option across all lines of treatment for advanced colorectal cancer. We will lose U.S. exclusivity for Camptosar in 2008.

Xalatan/Xalacom, Sutent is an oral multi-kinase inhibitor that combines anti-angiogenic and anti-tumor activity to inhibit the blood supply to tumors and has direct anti-tumor effects. Sutent was approved by the FDA and launched in the U.S. in January 2006 for advanced renal cell carcinoma, including metastatic renal cell carcinoma, and gastrointestinal stromal tumors (GIST) after disease progression on, or intolerance to, imatinib mesylate. In the first quarter of 2007, the U.S. label was revised to include new first-line advanced renal cell carcinoma data. In January 2007, Sutent received full marketing authorization and extension of the indication to first-line treatment of advanced and/or metastatic renal cell carcinoma (mRCC), as well as approval as a second-line treatment for GIST, in the E.U. We believe that future growth of Sutent will be fueled by emerging new data in a range of potential new indications. Sutent recorded $248 million in worldwide revenues in the first six months of 2007.

Xalatan/Xalacom, a prostaglandin analogue used to lower the intraocular pressure associated with glaucoma and ocular hypertension, is one of the most-prescribedworld's leading branded glaucoma medicine in the world.medicines. Clinical data showing its advantages in treating intra-ocularintraocular pressure compared with beta blockers should support the continued growth of this important medicine. Xalacom, the only fixed combination prostaglandin (Xalatan) and beta blocker, is available primarily in European markets. Xalatan/Xalacom salesworldwide revenues grew 2%9% in the first six months of 20062007, compared to the same period in 2005.2006.

Zyrtecprovides strong, rapid and long-lasting relief for seasonal and year-round allergies and hives with once-daily dosing. Zyrtec continues to be the most-prescribed antihistamine in the U.S. in a challenging market. SalesWorldwide revenues increased 15%6% in the first six months of 20062007, compared to the same period in 2005. In February 2006,2006. We will lose U.S. exclusivity for Zyrtec in December 2007. Since we began a new DTC advertising campaign featuring new insight that allergy symptoms can worsen over time duesold our rights to exposure to new allergens.

Caduet,market Zyrtec over-the-counter in connection with the first multi-target single pill combining Norvasc and Lipitor, recorded worldwidesale of our Consumer Healthcare business, we expect no revenues infrom Zyrtec after the amountexpiration of $157 million with a growth rate of 116% for the first six months of 2006 compared to the same period in 2005. Caduet launched in the U.S. patent in May 2004 and continues to grow at significantly higher rates than the overall U.S. cardiovascular market. Caduet is also available in Mexico, Chile, Brazil, Philippines, Singapore, Malaysia, India, Korea, Canada and most recently, Caduet was launched in South Africa, Peru and Venezuela. In total, Caduet has now received approvals in 42 markets with drug applications pending in 19 additional markets. During 2006, Caduet is expected to launch in France, Spain, Austria and Turkey.December.

   

Chantix/Champix, the first new prescription treatment for smoking cessation in nearly a decade, became available to patients in the U.S. in late July 2006. On July 28, 2006, the Committee for Medicinal Products for Human Use (CHMP) issued a positive opinion recommending that the European Commission grant marketing authorization for Champix in Europe.

Animal Health

Revenues of our Animal Health business follow:

Three Months Ended

Six Months Ended

(millions of dollars)

July 1,
2007

July 2,
2006

% Change

  

July 1,
2007

July 2,
2006

% Change

  

Livestock products

$

379

$

359

6%

$

735

$

671

10 %

Companion animal products

253

224

13   

483

423

14    

Total Animal Health

$

632

$

583

9   

$

1,218

$

1,094

11    

Our Animal Health business is one of the largest in the three months and six months ended July 2, 2006 compared to the three months and six months ended July 3, 2005 follow:world.

Three Months Ended

Six Months Ended

(millions of dollars)

July 2,
2006

July 3,
2005

% Change

  

July 2,
2006

July 3,
2005

% Change

  

Livestock products

$

359

$

354

1%

$

671

$

657

2 %

Companion animal products

224

224

--   

423

416

2    

Total Animal Health

$

583

$

578

1   

$

1,094

$

1,073

2    

The increase in Animal Health revenues in the three monthssecond quarter and first six months ended July 2, 2006, asof 2007, compared to the same periods in 2005,2006, was primarily attributable to:

infor livestock products, the continued good performance of Draxxinour premium anti-infectives for cattle and swine, and intramammaries in the first half of 2007, as well as revenues from Embrex, Inc., which we acquired in the first quarter of 2007;

for companion animal products, the good performances of Revolution (a parasiticide for dogs and cats); Rimadyl (for treatment of respiratory diseasepain and inflammation associated with canine osteoarthritis and soft-tissue orthopedic surgery); and new product launches, such as Convenia (first-in-class single-dose treatment antibiotic therapy for dogs and cats), Slentrol (weight management for dogs) and Cerenia (treatment and prevention of vomiting in cattle and swine) in Europe and in the U.S.dogs); and

  

in companion animal, the continued good performance of Revolution (a parasiticide for dogs and cats), which had double-digit revenue growth in the U.S. for both the second quarter and first six months of 2006;

partially offset by:

a decline in U.S. Rimadyl revenues due to lower than anticipated NSAID market growth and intense branded competition, as well as increased generic competition in the European companion animal market; and

the unfavorablefavorable impact of the strengthening of the U.S. dollar relative to many foreign currencies.exchange.

Product Developments

We continue to invest in R&D to provide future sources of revenuerevenues through the development of new products, as well as through additional uses for existing in-line and alliance products. We have a broad and deep pipeline of medicines in development. However, there are no assurances as to when, or if, we will receive regulatory approval for additional indications for existing products or any of our other products in development.

Certain Below are significant regulatory actions by, and filings pending with, the FDA and other major regulatory authorities follow:authorities.

Recent FDA Approvals:

Product

Indication

   

Date Approved

  

Selzentry/(maraviroc)

ChantixTreatment of human immuno-deficiency virus/acquired immune deficiency (HIV) in CCR5-tropic treatment-experienced patients

August 2007

Lyrica

Nicotine-receptor partial agonist for smoking cessationTreatment of fibromyalgia

June 2007

Fragmin

For the prevention of blood clots in patients with cancer

May 20062007

   

GenotropinLipitor

TreatmentSecondary prevention of short stature and growth problems resulting from Turner's syndrome

May 2006

Geodon

Liquid oral suspensioncardiovascular (CV) events in patients with established coronary heart disease (CHD)

March 2006

Eraxis

Treatment of candidemia and invasive candidiasis

February 2006

Treatment of esophageal candidiasis

February 2006

Exubera

Inhaled form of insulin for use in adults with type 1 and type 2 diabetes

January 2006

Sutent

Treatment of mRCC and GIST

January 20062007

Pending U.S. New Drug Applications (NDAs) and Supplemental Filings:

Product

Indication

 

Date Submitted

   

CelebrexZmax

Juvenile rheumatoid arthritisBacterial infections-sustained release-Pediatric acute otitis media filing

JuneNovember 2006

   

   

Lipitor

Secondary prevention of cardiovascular (CV) events in patients with established coronary artery disease (CAD)

May 2006

Fesoterodine(a)

Treatment of overactive bladder

March 2006

   

Aricept

Treatment of severe Alzheimer's disease

August 2005

Vfend

PediatricFungal infections-Pediatric filing

June 2005

  

Zeven (dalbavancin)dalbavancin

Treatment of Gram-positivecomplicated skin/skin structure gram-positive bacterial infections

December 2004

(a)

We received an "approvable" letter from the FDA for fesoterodine for the treatment of overactive bladder in January 2007.

Regulatory review of fesoterodine is progressing in the U.S. and fesoterodine was approved in the E.U. in April 2007. We are working with Schwarz Pharma, the licensor, to scale up manufacturing and define sourcing alternatives. Launch is planned for the latter half of 2008 in Europe and, subject to FDA approval, early 2009 in the U.S.

In June 2006, the FDA designated as approvable the NDA for dalbavancin. In June 2007, we re-submitted our NDA filing for dalbavancin and we anticipate a successful resolution of outstanding issues to allow final FDA approval by year-end 2007 and launch in early 2008.

We received "not-approvable" letters from the FDA for Oporialasofoxifene for the prevention of post-menopausal osteoporosis in September 2005 and for the treatment of vaginal atrophy in January 2006. We are currently in discussionshave reviewed the viability of the lasofoxifene treatment program using three-year interim data from the Postmenopausal Evaluation And Risk-reduction with the FDA regarding these letters,Lasofoxifene (PEARL) study, and we continue to develop Oporia. In March 2006, we received a "not-approvable" letter for Fragmin for use in oncology patients, andbased on our assessment, we are currentlyplanning to file a new NDA for the treatment of post-menopausal osteoporosis in discussions with the FDA regarding this letter as well.fourth quarter of 2007. In September 2005, we received a "not-approvable" letter for Dynastat (parecoxib), an injectable prodrug for valdecoxib for the treatment of acute pain. We have had discussions with the FDA regarding this letter, and we are developingconsidering plans to seek to address the FDA's concerns

In June 2006, after certain decisions by the FDA, we notified Neurocrine that we are returning the development and marketing rights for indiplon, a medicine in development to treat insomnia, to Neurocrine. This includes both the collaboration to develop and co-market indiplon in the U.S., as well as Pfizer's exclusive license to develop and market indiplon outside of the U.S.

In June 2006, the FDA designated as approvable the NDA for Zeven (dalbavancin). We now anticipate a successful resolution of outstanding issues to allow final FDA approval and launch in 2007.

In the third quarter of 2006, we completed the acquisition of exclusive worldwide rights to the new drug candidate fesoterodine, for treatment of overactive bladder, from Schwarz Pharma AG for approximately $100 million in cash, which will be expensed in the third quarter of 2006. Additional payments of up to $110 million will be payable upon regulatory approvals in the U.S. and Europe and other performance milestones. In March 2006, Schwarz submitted an NDA for fesoterodine with both the FDA and the European Medicines Evaluation Agency (EMEA). Also in the third quarter of 2006, we reached an agreement with Bayer Pharmaceuticals Corporation to acquire exclusive worldwide rights for several compounds for treatment of obesity and diabetes.  concerns.

Other Regulatory Approvals and Filings:

    

Product

Description of Event

Date Approved

  

Date Submitted

  

 

 

Aricept

Approval in Canada for treatment of severe Alzheimer's disease

June 2007

--

Zmax

Fesoterodine

Approval in the E.U. for sustained release formtreatment of overactive bladder

June 2006April 2007

--

    

Lipitor

Approval in Canada to reduce the E.U. for primary preventionrisk of CV eventsmyocardial infarction in high coronary heart disease risk patients without established CADwith clinically evident CHD

May 2006April 2007

--

  

Sutent

Approval in Canada for GIST

May 2006

--

Aromasin

Approval in Canada for early breast cancer

May 2006

--

Vfend

Approval in Canada for the powder form oral suspension

May 2006

--

Revatio

Approval in Canada for treating pulmonary arterial hypertension

May 2006

--

Zyvox

Approval in Japan for methicillin-resistant staphylococcus aureus

April 2006

--

Zoloft

Approval in Japan for treatment of depression

April 2006

--

Detrol/Detrol LA

Approval in Japan for treatment of overactive bladder

April 2006

--

Celebrex

Submitted in the E.U. for the treatment of ankylosing spondylitis

--

April 2006

Lyrica

Approval in the E.U. for treatment of GAD in adults

March 2006

--

Application submitted in the E.U. for the treatment of broad neuropathic pain

--

January 2006

Fesoterodine

Application submitted in the E.U. for treatment of overactive bladder

--

March 2006

Chantix/Champix

Application submitted in Canada for smoking cessation

--

February 2006

Application submitted in the E.U. for smoking cessation(a)

--

November 2005

Exubera

Approval in the E.U. as an inhaled form of insulin for use in adults with type 1 and 2 diabetes

January 2006

--

Application submitted in Canada as an inhaled form of insulin for use in adults with type 1 and 2 diabetes

--March 2007

April 2006--

   

Macugen

ApprovalApplication submitted in E.U.Japan for age-related macular degeneration (AMD)

--

March 2007

Celebrex

Approval in the E.U. for the treatment of ankylosing spondylitis

February 2007

--

Application submitted in Japan for lower-back pain

--

February 2007

Approval in Japan for treatment of osteoarthritis and rheumatoid arthritis

January 20062007

--

   

Sildenafil

Application submitted in SwitzerlandJapan for AMDpulmonary arterial hypertension

--

January 2005February 2007

   

Celsentri (maraviroc)

Application submitted in AustraliaCanada for AMDthe treatment of HIV in CCR5-tropic treatment-experienced patients

--

September 2004February 2007

Application submitted in the E.U. for the treatment of HIV in CCR5-tropic treatment-experienced patients (a)

--

December 2006

Chantix/Champix

Approval in Canada as an aid to smoking cessation

January 2007

--

Application submitted in Japan as an aid to smoking cessation

--

June 2006

Somavert

Approval in Japan for acromegaly

January 2007

--

   

Sutent

Application submittedApproval in the E.U. for mRCC andas a first-line treatment

January 2007

--

Approval in the E.U. for GIST(b) as a second-line treatment

January 2007

--

Application submitted in Japan for mRCC

--

August 2005December 2006

Application submitted in Japan for GIST

--

December 2006

Application submitted in Canada for first-line treatment of mRCC

--

December 2005

--

Somavert

Application submitted in Japan for acromegaly

--

May 2005October 2006

   

GenotropinSpiriva

Application submitted in the E.U. - Respimat device for chronic obstructive pulmonary disease

--

September 2006

Eraxis/Ecalta(b)

Application submitted in the E.U. for treatment of candidemia and candidiasis

--

September 2006

Inspra

Application submitted in Japan for treatment of short stature and growth problemshypertension

--

July 2004May 2002

   

(a)

OnIn July 28, 2006,2007, the Committee for Medicinal Products for Human Use (CHMP) issued a positive opinion recommending that the European Commission grant marketing authorization for Celsentri (maraviroc) in Europe.

(b)

In July 2007, the CHMP issued a positive opinion recommending that the European Commission grant marketing authorization for ChampixEcalta (Eraxis) for the treatment of invasive candidiasis in adult non-neutropenic patients in Europe.

(b)

On July 27, 2006, Sutent received conditional marketing authorization for both the mRCC and GIST indications in Europe from the European Commission. The conditional approval process is designed to get treatments with favorable benefit/risk profiles for life-threatening indications to target patient populations earlier; final approval is contingent on the provision of additional supportive information. This is the first time the European Commission has approved a new oncology drug under the conditional approval process.

Ongoing or planned clinical trials for additional uses and dosage forms for our products include:

Product

Indication

  

Camptosar IVCelebrex

Adjuvant colorectal cancer

Gastric cancerAcute gouty arthritis

   

Geodon/Zeldox

Bipolar relapse prevention,prevention; bipolar pediatricpediatric; adjunctive depression

   

Lyrica

Fibromyalgia, generalizedGeneralized anxiety disorderdisorder; epilepsy monotherapy

   

Sutent

Breast cancer

Revatio

Pediatric pulmonary arterial hypertension

   

MacugenSutent

Diabetic macular edemaBreast cancer; colorectal cancer; non-small cell lung cancer; liver cancer

   

ZyvoxMacugen

Catheter-related infections

Bone and joint infectionsDiabetic macular edema

Drug candidates in late-stage development include maraviroc (UK-427,857),CP-945,598, a CCR-5cannibinoid-1 receptor antagonist for HIV; torcetrapib/atorvastatin,treatment of obesity; axitinib, a combination CETP inhibitor/statinmulti-targeted receptor kinase for heart disease; asenapine, for schizophreniatreatment of thyroid cancer and bipolar disorder, under co-development with Akzo Nobel's Organon healthcare unit;pancreatic cancer; Zithromax/chloroquine for treatment of malaria; PF-3512676, a toll-like receptor 9 agonist for non-small cell lung cancer developed in partnership with Coley Pharmaceutical Group, Inc.; and CP-675,206, an anti-CTLA4 monoclonal antibody for melanoma. The FDA has granted fast-track designationmelanoma; Sutent for maraviroc's clinical development program.

Torcetrapib/atorvastatin,treatment of metastatic breast cancer, colorectal cancer and lung cancer; Selzentry/Celsentri/(maraviroc) for treatment of HIV in CCR5-tropic treatment-naive patients; and apixaban for the prevention and treatment of venous thromboembolism and the prevention of stroke in patients with atrial fibrillation, which combines the new chemical entity torcetrapib (a CETP inhibitor discovered by Pfizer that raises HDL cholesterol) with atorvastatin (Lipitor), is continuing in global Phase 3 clinical trials. This comprehensive 12,000-subject development program includes three comparative atherosclerotic imaging trials (a coronary intravascular ultrasound study and two carotid ultrasound studies), as well as a full range of blood-lipid efficacy studies comparing torcetrapib/ atorvastatin to Lipitor, other statins and fibrates. We anticipate completion of the three ongoing imaging trials by the end of this year. Assuming that we see the expected improvements over the comparative agent (Lipitor) in these imaging studies, we plan to file the torcetrapib/atorvastatin NDA in 2007.

In addition to these Phase 3 studies, the development program includes a definitive mortality and morbidity trial that is enrolling 15,000 patients.

Despite effective treatments, cardiovascular disease remains the number one killer worldwide with a residual relative risk of 60% to 70% after treatment with statins. Therefore, the primary objective of the torcetrapib/atorvastatin development program is to provide clear evidence that substantially raising HDL cholesterol and further lowering LDL cholesterol can reduce cardiovascular risk beyond what can be achieved with current treatments. Torcetrapib is being developed in collaboration with atorvastatin in order to rigorously test this hypothesis andBMS.

In June 2007, we announced the new CETP inhibition mechanismdiscontinuation of action. Thisa development program represents a major commitment by Pfizer to significantly advance the understanding of lipids and atherosclerosis in order to provide an important new toolnon-small cell lung cancer for patients and prescribersPF-3,512,676 in preventing and treating the global burden of cardiovascular disease. In addition to the torcetrapib/atorvastatin development program, Pfizer plans to develop torcetrapib as concurrent therapy to be usedcombination with other statins or lipid-lowering medications.cytotoxic chemotherapy. We licensed PF-3,512,676 from Coley Pharmaceutical Group, Inc. in 2005.

Additional product-related programs are in various stages of discovery and development.

Also, see our discussion in the "Our Strategic Initiatives--Strategy and Recent Collaborations:

We have entered into promising research collaborations with NicOx S.A. in ophthalmic disorders, NOXXON Pharma AG in obesity,Transactions: Acquisitions, Licensing and Incyte Corporation for CCR2 antagonists for use in a broad rangeCollaborations" section of diseases.

this MD&A.

COSTS AND EXPENSES

Cost of Sales

Cost of sales increased 2% and decreased 5%18% in the three months and six months ended July 2, 2006 assecond quarter of 2007, compared to the same periodssecond quarter of 2006, and 15% in 2005.the first six months of 2007, compared to the first six months of 2006. Cost of sales as a percentage of revenues decreasedincreased 3.8 percentage points in the three months and six months ended July 2, 2006 assecond quarter of 2007, compared to the same periods in 2005. The decrease reflects a favorable geographic mix, representing a greater portionsecond quarter of sales2006, and 2.3 percentage points in the U.S.; operational efficiencies, reflecting first six months of 2007, compared to the first six months of 2006. These increases reflect:

unfavorable impact of product and geographic mix on our average cost of sales as a result of the loss of U.S. exclusivity for products (such as Zoloft and Norvasc) and lower sales of Lipitor;

the impact of higher AtS implementation costs of $170 million in the second quarter of 2007, compared to $104 million in the second quarter of 2006, and $264 million in the first six months of 2007, compared to $228 million in the first six months of 2006.

costs of $45 million for the second quarter of 2007 and $80 million for the first six months of 2007, related to business transition activities, associated with the sale of our Consumer Healthcare business, completed in December 2006; and

the unfavorable impact of foreign exchange on expenses,

partially offset by:

savings related to our AtS productivity initiative; the favorable impact on expenses of foreign exchange; as well as the impact in the prior-year period of inventory write-offs of $56 million related to the suspension of Bextra sales, partially offset by higher costs related to our AtS productivity initiative.

Selling, Informational and Administrative Expenses

Selling, informational and administrative (SI&A) expenses increased 3%decreased 1% in both the second quarter of 2007 and decreased 2% in the three months andfirst six months ended July 2, 2006, asmonth of 2007, compared to the same periods in 2005. The increase in the three months ended July 2, 2006, reflected higher costs related to our AtS productivity initiative and expenses related to share-based payments, which reflects:

timing considerations associated with our annual investments in promotional programs; and

savings related to our AtS productivity initiative,

partially offset by savings related to our AtS productivity initiative and the favorable impact on expenses of foreign exchange. The decrease in the six months ended July 2, 2006 reflected savings related to our AtS productivity initiative and the favorable impact on expenses of foreign exchange.by:

the impact of higher AtS implementation costs of $79 million in the second quarter of 2007, compared to $58 million in the second quarter of 2006, and $128 million in the first six months of 2007, compared to $97 million for the first six months of 2006; and

the unfavorable impact of foreign exchange on expenses.

Research and Development Expenses

R&DResearch and development (R&D) expenses decreased 5% and 7%increased 24% in the three months and six months ended July 2, 2006, assecond quarter of 2007, compared to the same periodssecond quarter of 2006, and 17% in 2005, reflecting the first six months of 2007, compared to the first six months of 2006, which reflects:

an upfront payment to BMS of $250 million and additional payments to BMS related to product development efforts, in connection with our collaboration to develop and commercialize apixaban, recorded in the second quarter of 2007;

a one-time R&D milestone due to us from sanofi-aventis (approximately $118 million) recorded in the first quarter of 2006;

the impact of higher AtS implementation costs of $131 million in the second quarter of 2007, compared to $40 million in the second quarter of 2006, and $162 million for the first six months of 2007, compared to $62 million in the first six months of 2006;

the unfavorable impact of foreign exchange on expenses,

partially offset by:

savings related to our AtS productivity initiative, a R&D milestone due to us from sanofi-aventis (approximately $118 million, pre-tax, in the first quarter of 2006) and the favorable impact on expenses of foreign exchange.initiative.

Merger-RelatedAcquisition-Related In-Process Research and Development Charges

The estimated fair value of Merger-relatedAcquisition-related in-process research and development charges (IPR&D) is expensed at acquisition date. In 2006, IPR&D of $283 million primarily related to our acquisitions of BioRexis Pharmaceutical Corp. and Embrex, Inc. was recorded in the first quarter 2007 and $513 million, pre-tax,primarily related to the acquisition of Rinat Neuroscience Corp., was recorded in the second quarter and first six months of 2006 primarily related to our acquisition of Rinat on May 16, 2006, as compared to $262 million, pre-tax, recorded in the first six months of 2005, which primarily related to our acquisition of Idun Pharmaceuticals, Inc. on April 12, 2005.2006.

Adapting to Scale Productivity Initiative

In connection with the AtS productivity initiative, which was launched in early 2005 Pfizerand broadened in October 2006, our management has performed a comprehensive review of our processes, organizations, systems and decision-making procedures in a company-wide effort to improve performance and efficiency. We continueOn January 22, 2007, we announced additional plans to expectchange the costs associated with this multi-year effortway we run our businesses to continue through 2008meet the challenges of a changing business environment and to total approximately $4 billion to $5 billion, on a pre-tax basis.take advantage of the diverse opportunities in the marketplace. We continue to expect thatare generating net cost savings from our AtS productivity initiative will bereductions through site rationalization in excess of $2 billion in 2006, growing to about $4 billion annually upon completion in 2008, notwithstanding the planned divestiture of our Consumer Healthcare businessresearch and the expensemanufacturing, streamlined organizational structures, sales force and staff function reductions, associated with that business. Savings realized during the second quarter and first six months of 2006 total approximately $500 millionincreased outsourcing and $1 billion, respectively. procurement savings.

The actions associated with the expanded AtS productivity initiative will include restructuring charges, such as asset impairments, exit costs and severance costs (including any related impacts to our benefit plans, including settlements and curtailments) and associated implementation costs, such as accelerated depreciation charges, primarily associated with plant network optimization efforts, and expenses associated with system and process standardization and the expansion of shared services (seeservices. (See Notes to the Condensed Consolidated Financial Statements - Statements-Note 6,5. Adapting to Scale Productivity InitiativeInitiative.). The strengthening of the euro and other currencies relative to the dollar, while favorable on Revenues, has had an adverse impact on our expenses, including the reported impact of these cost reduction efforts.

We incurred the following costs in connection with our AtS productivity initiative:

Three Months Ended

Six Months Ended

Three Months Ended

Six Months Ended

(millions of dollars)

July 2, 
2006 

July 3,
2005

July 2, 
2006 

July 3,
2005

July 1,
2007

  

July 2,
2006

  

July 1,
2007

July 2,
2006

Implementation costs(a)

$

180

$

33

$

365

$

33

$

317 

$

180 

$

491 

$

365 

Restructuring charges(b)

262

21

556

21

1,035 

262 

1,830 

556 

Total AtS costs

$

442

$

54

$

921

$

54

$

1,352 

$

442 

$

2,321 

$

921 

   

(a)

IncludedFor the second quarter of 2007, included in Cost of sales ($170 million), Selling, informational and administrative expenses ($79 million), Research and development expenses ($131 million) and Other (income)/deductions - net ($63 million income). For the second quarter of 2006, included in Cost of sales ($104 million),Selling, informational and administrative expenses ($58 million), Research and developmentexpenses ($40 million) and in Other (income)/deductions - net ($22 million income) for.For the threefirst six months ended July 2,of 2007, included in Cost of sales ($264 million), Selling, informational and administrative expenses ($128 million), Research and development expenses ($162 million) and Other (income)/deductions - net ($63 million income). For the first six months of 2006, and included in Cost of sales ($228 million),Selling, informational and administrative expenses ($97 million), Research and developmentexpenses ($62 million) and in Other (income)/deductions - net ($22 million income) for the six months ended July 2, 2006. Included in Cost of sales ($1 million), Selling, informational and administrative expenses ($21 million), and Research and developmentexpenses ($11 million) for the three months and six months ended July 3, 2005..

(b)

Included in Restructuring charges and merger-relatedacquisition-related costs.

Merger-Related Costs

In connection with acquisitions, we typically restructure and integrate the operations of the acquired companies to eliminate duplicative facilities and reduce costs. In certain instances, legacy Pfizer operations may be impacted by restructuring actions.

We incurred the following merger-related costs:

Three Months Ended

Six Months Ended

(millions of dollars)

July 2,
2006

July 3,
2005

July 2,
2006

July 3,
2005

  

Integration costs

$

3

$

191

$

5

$

293

Restructuring charges

3

52

6

166

Total merger-related costs(a)

$

6

$

243

$

11

$

459

(a)

Included in Restructuring charges and merger-related costs. Amounts in 2005 primarily relate to our acquisition of Pharmacia Corporation (Pharmacia), which was completed on April 16, 2003.

Restructuring charges included severance, costs of vacating duplicative facilities, contract termination and other exit costs.

Other (Income)/Deductions - NetDeductions-Net

In the second quarter and first six monthmonths of 2005,2007, we recorded impairment charges of $1.1 billion relatedhigher net interest income compared to the developed technology rights for Bextra, a selective COX-2 inhibitor,same periods in 2006, due primarily to higher interest rates and $7 million related toan increase in our net financial assets, reflecting proceeds of $16.6 billion from the write-offsale of machinery and equipment, both of which are includedour Consumer Healthcare business in Other (income)/deductions - net. Substantially all of these charges were recorded in the first quarter of 2005.late December 2006.

PROVISION/(BENEFIT)PROVISION FOR TAXES ON INCOME

On January 25,In the first quarter of 2006, the Company waswe were notified by the Internal Revenue Service (IRS) Appeals Division that a resolution had been reached on the matter that we were in the process of appealing related to the tax deductibility of aan acquisition-related breakup fee paid by the Warner-Lambert Company in 2000. As a result, in the first quarter of 2006, we recorded a tax benefit of approximately $441 million related to the resolution of this issue.

On January 23, 2006, the IRS issued final regulations on Statutory Mergers and Consolidations, which impacted certain prior-period transactions. In the first quarter of 2006, we recorded a tax benefit of $217 million, reflecting the total impact of these regulations.

In the second quarter of 2005, we recorded a tax benefit of $586 million primarily related to the resolution of certain tax positions.

Our effective tax rate for continuing operations was 16.8% for the second quarter of 2007, compared to 25.6% for the second quarter of 2006, and 16.9% for the first six months of 2007, compared to 14.3% for the first six months of 2006 compared to 37.4% in the same period in 2005.2006. The lower tax rate for the first six monthssecond quarter of  2007 compared to the second quarter of 2006, primarily reflects the impact of a $513 million charge in the second quarter of 2006 for IPR&D, which is primarily due tonot deductible for tax benefits relatedpurposes, as well as the volume and geographic mix of restructuring charges in the second quarter of 2007 as compared to the resolution of the tax matter and the changesame period in tax regulations as discussed above.2006. The higher tax rate for the first six months of 2005 is primarily due2007 compared to the recordingfirst six months of a $1.7 billion2006, primarily reflects certain one-time tax benefits in 2006 associated with favorable tax legislation and the resolution of certain tax positions in the first quarter of 2006, as discussed above, partially offset by the impact of the $283 million charge relatedfor IPR&D in the first six months of 2007, compared to our decision to repatriate certain foreign earnings under the American Jobs Creation Act of 2004 (the Jobs Act).$513 million charge for the same period in 2006, which is not deductible for tax purposes, among other factors. (See Notes to Condensed Consolidated Financial Statements--Note 8,Statements-Note 6. Taxes on IncomeIncome.).

DISCONTINUED OPERATIONS - NET OF TAX

In JuneDecember 2006, we entered into an agreement to sellsold our Consumer Healthcare business and this business has been presented as a discontinued operation.  The increase in pre-tax incomeoperation for discontinued operations of 19% and 9% for the three months and six months ended July 2, 2006 compared to the sameall periods in 2005 is primarily due to pre-tax losses from discontinued operations in 2005 related to certain European generics businesses, our in-vitro allergy and autoimmune diagnostics testing, and surgical ophthalmics, as well as femhrt women's health product lines, while pre-tax income from our Consumer Healthcare business increased 10% and decreased 2% for the three months and six months ended July 2, 2006, compared to the same periods in 2005. presented.

ADJUSTED INCOME

General Description of Adjusted Income Measure

Adjusted income is an alternative view of performance used by management and we believe that investors' understanding of our performance is enhanced by disclosing this performance measure. The Company reportsWe report Adjusted income in order to portray the results of our major operations--the discovery, development, manufacture, marketing and sale of prescription medicines for humans and animals--prior to considering certain income statement elements. We have defined Adjusted income as Net income before significantthe impact of purchase accounting for acquisitions, merger-relatedacquisition-related costs, discontinued operations and certain significant items. The Adjusted income measure is not, and should not be viewed as, a substitute for U.S. GAAP Net income.

The Adjusted income measure is an important internal measurement for Pfizer. We measure the performance of the overall Company on this basis. The following are examples of how the Adjusted income measure is utilized.

Senior management receives a monthly analysis of theour operating results of our Company that is prepared on an Adjusted income basis;

  

TheOur annual budgets of our Company are prepared on an Adjusted income basis; and

  

Annual and long-term compensation, including annual cash bonuses, merit-based salary adjustments and stock options,share-based payments for various levels of management, is based on financial measures that include Adjusted income. The Adjusted income measure currently represents a significant portion of target objectives that are utilized to determine the annual compensation for various levels of management, although the actual weighting of the objective may vary by level of management and job responsibility and may be considered in the determination of certain long-term compensation plans. The portion of senior management's bonus, merit-based salary increase and stock option awards based on the Adjusted income measure ranges from 10% to 30%.

Despite the importance of this measure to management in goal setting and performance measurement, we stress that Adjusted income is a non-GAAP financial measure that has no standardized meaning prescribed by U.S. GAAP and, therefore, has limits in its usefulness to investors. Because of its non-standardized definition, Adjusted income (unlike U.S. GAAP Net income) may not be comparable with the calculation of similar measures for other companies. Adjusted income is presented solely to permit investors to more fully understand how management assesses the performance of our Company.performance.

We also recognize that, as an internal measure of performance, the Adjusted income measure has limitations and we do not restrict our performance-management process solely to this metric. A limitation of the Adjusted income measure is that it provides a view of our Company's operations without including all events during a period such as the effects of an acquisition merger-related costs or amortization of purchased intangibles and does not provide a comparable view of our performance to other companies in the pharmaceutical industry. We also use other specifically tailored tools designed to ensure the highest levels of performance in our Company.performance. For example, our R&D organization has productivity targets, upon which its effectiveness is measured. In addition, for senior levelsPerformance Share Awards grants made in 2006, the first half of management, a portion of their long-term compensation is2007 and future years will be paid based on U.S. GAAP Net income.a non-discretionary formula that measures our performance using relative total shareholder return.

Purchase Accounting Adjustments

Adjusted income is calculated prior to considering certain significant purchase-accounting impacts, such as those related to our acquisitions of Pharmacia,BioRexis Pharmaceutical Corp., Embrex, Inc., Rinat, Idun, and sanofi-aventis' rights to Exubera, as well as net asset acquisitions. These impacts can include charges for purchased in-process R&D, the incremental charge to cost of sales from the sale of acquired inventory that was written up to fair value and the incremental charges related to the amortization of finite-lived intangible assets for the increase to fair value. Therefore, the Adjusted income measure includes the revenues earned upon the sale of the acquired products without considering the aforementioned significant charges.

Certain of the purchase-accounting adjustments associated with a business combination, such as the amortization of intangibles acquired in connection with our acquisition of Pharmacia in 2003, can occur for up to 40 years (these assets have a weighted-average useful life of approximately nine years), but this presentation provides an alternative view of our performance that is used by management to internally assess business performance. We believe the elimination of amortization attributable to acquired intangible assets provides management and investors an alternative view of our business results by trying to provide a degree of parity to internally developed intangible assets for which research and development costs have been previously expensed.

However, a completely accurate comparison of internally developed intangible assets and acquired intangible assets cannot be achieved through Adjusted income. This component of Adjusted income is derived solely with the impacts of the items listed in the first paragraph of this section. We have not factored in the impacts of any other differences in experience that might have occurred if Pfizerwe had discovered and developed those intangible assets on itsour own, and this approach doesis not intendintended to be representative of the results that would have occurred in those circumstances. For example, our research and development costs in total, and in the periods presented, may have been different; our speed to commercialization and resulting sales, if any, may have been different; or our costs to manufacture may have been different. In addition, our marketing efforts may have been received differently by our customers. As such, in total, there can be no assurance that our Adjusted income amounts would have been the same as presented had Pfizerwe discovered and developed the acquired intangible assets.

Merger-RelatedAcquisition-Related Costs

Adjusted income is calculated prior to considering integration and restructuring costs associated with business combinations because these costs are unique to each transaction and represent costs that were incurred to restructure and integrate two businesses as a result of the acquisition decision. For additional clarity, only restructuring and integration activities that are associated with a purchase business combination or a net-asset acquisition are included in merger-relatedacquisition-related costs. We have not factored inmade no adjustments for the impacts of synergies that would have resulted had these costs not been incurred.resulting synergies.

We believe that viewing income prior to considering these charges provides investors with a useful additional perspective because the significant costs incurred in a business combination result primarily from the need to eliminate duplicate assets, activities or employees--a natural result of acquiring a fully integrated set of activities. For this reason, we believe that the costs incurred to convert disparate systems, to close duplicative facilities or to eliminate duplicate positions (for example, in the context of a business combination) can be viewed differently from those costs incurred in other, more normal business contexts.

The integration and restructuring costs associated with a business combination may occur over several years with the more significant impacts ending within three years of the transaction. Because of the need for certain external approvals for some actions, the span of time needed to achieve certain restructuring and integration activities can be lengthy. For example, due to the highly regulated nature of the pharmaceutical business, the closure of excess facilities can take several years as all manufacturing changes are subject to extensive validation and testing and must be approved by the FDA. In other situations, we may be required by local laws to obtain approvals prior to terminating certain employees. This approval process can delay the termination action.

Discontinued Operations

Adjusted income is calculated prior to considering the results of operations included in discontinued operations, such as our Consumer Healthcare business, which we have agreed to sell,sold in December 2006, as well as any related gains or losses on the sale of such operations. We believe that this presentation is meaningful to investors because, while we review our businesses and product lines periodically for strategic fit with our operations, we do not build or run our businesses with an intent to sell them.

Certain Significant Items

Adjusted income is calculated prior to considering certain significant items. Certain significant items represent substantive, unusual items that are evaluated on an individual basis. Such evaluation considers both the quantitative and the qualitative aspect of their unusual nature. Unusual, in this context, may represent items that are not part of our ongoing business; items that, either as a result of their nature or size, we would not expect to occur as part of our normal business on a regular basis; items that would be non-recurring; or items that relate to products we no longer sell. While not all-inclusive, examples of items that could be included as certain significant items would be a major non-acquisition-related restructuring charge and associated implementation costs for a program which is specific in nature with a defined term, such as those related to our AtS productivity initiative; costs associated with a significant recall of one of our products; charges related to sales or disposals of products or facilities that do not qualify as discontinued operations as defined by U.S. GAAP; amounts associated with transition service agreements in support of discontinued operations after sale; certain intangible asset impairments; adjustments related to the resolution of certain tax positions; the impact of adopting certain significant, event-driven tax legislation, such as charges attributable to the repatriation of foreign earnings in accordance with the Jobs Act; or possible charges related to legal matters, such as certain of those discussed in Legal Proceedings in our Form 10-K and in Part II: Other Information; Item 1, Legal Proceedings included in our Form 10-Q filings. Normal, ongoing defense costs of the Company or settlements and accruals on legal matters made in the normal course of our business would not be considered a certain significant item.

Reconciliation

A reconciliation between Net income, as reported under U.S. GAAP, and Adjusted income follows:

Three Months Ended

Six Months Ended

Three Months Ended

Six Months Ended

(millions of dollars)

July 2, 
2006 

July 3, 
2005 

% Incr./
(Decr.)

  

July 2, 
2006 

July 3, 
2005 

% Incr./
(Decr.)

July 1, 
2007 

July 2, 
2006 

% Incr./
(Decr.)

  

July 1, 
2007 

July 2, 
2006 

% Incr./
(Decr.)

Reported net income

$

2,415 

$

3,463 

(30)%

$

6,526 

$

3,763 

73%

$

1,267 

$

2,415 

(48)%

$

4,659 

$

6,526 

(29)%

Purchase accounting adjustments - net of tax

1,085 

815 

33    

1,666 

1,436 

16   

597 

1,085 

(45)   

1,444 

1,666 

(13)   

Merger-related costs - net of tax

172 

(99)   

320 

(98)  

Acquisition-related costs - net of tax

10 

303    

23 

327   

Discontinued operations - net of tax

(125) 

(88)

43    

(230)

(232)

--   

78  

(125) 

*    

47 

(230)

*   

Certain significant items - net of tax

286 

(1,042)

(127)   

46 

1,913 

(98)  

992 

286 

247    

1,575 

46 

M+   

Adjusted income

$

3,663 

$

3,320 

10    

$

8,013 

$

7,200 

11   

$

2,944 

$

3,663 

(20)   

$

7,748 

$

8,013 

(3)   

* Calculation not meaningful.

M+ Change greater than one thousand percent.

Certain amounts and percentages may reflect rounding adjustments.

Adjusted income as shown above excludes the following items:

Three Months Ended

Six Months Ended

Three Months Ended

Six Months Ended

(millions of dollars)

July 2, 
2006 

July 3, 
2005 

  

July 2, 
2006 

July 3, 
2005 

July 1, 
2007 

July 2, 
2006 

July 1, 
2007 

July 2, 
2006 

Purchase accounting adjustments, pre-tax:

In-process research and development charges(a)

$

513 

$

260 

$

513 

$

262 

Intangible amortization and other(b)

801 

826 

1,611 

1,680 

Purchase accounting adjustments:

Intangible amortization and other(a)

$

782 

$

801 

$

1,607 

$

1,611 

In-process research and development charges(b)

-- 

513 

283 

513 

Total purchase accounting adjustments, pre-tax

1,314 

1,086 

2,124 

1,942 

782 

1,314 

1,890 

2,124 

Income taxes

(229)

(271)

(458)

(506)

(185)

(229)

(446)

(458)

Total purchase accounting adjustments - net of tax

1,085 

815 

1,666 

1,436 

597 

1,085 

1,444 

1,666 

Merger-related costs, pre-tax:

Acquisition-related costs:

Integration costs(c)

191 

293 

14 

37 

Restructuring charges(c)

52 

166 

(4)

Total merger-related costs, pre-tax

243 

11 

459 

Total acquisition-related costs, pre-tax

16 

33 

11

Income taxes

(4)

(71)

(6)

(139)

(6)

(4)

(10)

(6)

Total merger-related costs - net of tax

172 

320 

Discontinued operations, pre-tax:

Total acquisition-related costs - net of tax

10 

23 

Discontinued operations:

Income from discontinued operations (d)

(160)

(134)

(315)

(290)

--  

(160)

--  

(315)

Gains on sales of discontinued operations(d)

(26)

-- 

(31)

(65)

(Gains)/losses on sales of discontinued operations(d)

79 

(26)

39 

(31)

Total discontinued operations, pre-tax

(186)

(134)

(346)

(355)

79 

(186)

39 

(346)

Income taxes

61 

46 

116 

123 

(1)

61 

116 

Total discontinued operations - net of tax

(125)

(88)

(230)

(232)

78 

(125)

47 

(230)

Certain significant items, pre-tax

Asset impairment charges (e)

-- 

-- 

-- 

1,213 

Sanofi-aventis research and development milestone(f)

-- 

-- 

(118)

-- 

Certain significant items:

Restructuring charges - Adapting to Scale(c)

262 

21 

556 

21 

1,035 

262 

1,830 

556 

Implementation costs - Adapting to Scale(g)

180 

33 

365 

33 

Gain on disposals of investments and other(h)

(23)

-- 

(74)

-- 

Implementation costs - Adapting to Scale(e)

317 

180 

491 

365 

Consumer Healthcare business transition activity(f)

(7)

--  

(16)

--  

Sanofi-aventis research and development milestone(g)

-- 

--  

--  

(118)

Other(h)

25 

(23)

25  

(74)

Total certain significant items, pre-tax

419 

54 

729 

1,267 

1,370 

419 

2,330 

729 

Income taxes

(133)

(20)

(242)

(467)

(378)

(133)

(755)

(242)

Resolution of certain tax positions(i)

-- 

(586)

(441)

(586)

-- 

--  

-- 

(441)

Tax impact of the repatriation of foreign earnings(i)

-- 

(490)

-- 

1,699 

Total certain significant items - net of tax

286 

(1,042)

46 

1,913 

992 

286

1,575 

46 

Total purchase accounting adjustments, merger-related costs, discontinued operations and certain significant items - net of tax


$

1,248 

$

(143)

$

1,487 

$

3,437 

Total purchase accounting adjustments, acquisition-related costs, discontinued operations and certain significant items - net of tax


$

1,677 


$

1,248 


$

3,089 

$

1,487 

  

(a)

Included in Merger-related in-process research and development charges.

(b)

Included primarily in Amortization of intangible assets.

(b)

Included in Acquisition-related in-process research and development charges, primarily related to our acquisitions of BioRexis Pharmaceutical Corp. and Embrex, Inc. in 2007 and Rinat in 2006.

(c)

Included in Restructuring charges and merger-relatedacquisition-related costs.

(d)

Discontinued operations - net of tax includes $109 million and $97 millionis primarily related to theour former Consumer Healthcare business for the three months ended July 2, 2006 and July 3, 2005 and $211 million and $213 million for the six months ended July 2, 2006 and July 3, 2005. These amounts do not include a substantial prospective gain on the planned divestiture.business. (See Notes to Condensed Consolidated Financial Statements-Note 4. Discontinued Operations.)

(e)

IncludedFor the second quarter of 2007, included in Cost of sales ($56170 million), Selling, informational and administrative expenses ($79 million), Research and development expenses ($131 million) and Other (income)/deductions - net ($63 million income). For the second quarter of 2006, included in Cost of sales ($104 million), Selling, informational and administrative expenses ($58 million), Research and development expenses ($40 million) and Other (income)/deductions -net ($22 million income).For the first six months of 2007, included in Cost of sales ($264 million), Selling, informational and administrative expenses ($128 million), Research and development expenses ($162 million) and Other (income)/deductions - net ($63 million income). For the first six months of 2006, included in Cost of sales ($228 million), Selling, informational and administrative expenses ($97 million), Research and development expenses ($62 million) and Other (income)/deductions - net ($22 million income).

(f)

Included in Revenues ($50 million), Cost of sales ($45 million), Selling, informational and administrative expenses ($5 million) and Other (income)/deductions - netdeductions-net ($1.2 billion)7 million income) for the second quarter of 2007, and included in Revenues ($94 million), Cost of sales ($80 million), Selling, informational and administrative expenses ($7 million) and Other (income)/deductions-net ($9 million income) for the first six months ended July 3, 2005.of 2007.

(f)(g)

Included in Research and development expenses.

(g)(h)

Included in Cost of sales ($104 million), Selling, informational and administrative expenses ($58 million), Research and developmentexpenses ($40 million) and in Other (income)/deductions - net ($22 million income) for the three months ended July 2, 2006 and included in Cost of sales ($228 million), Selling, informational and administrative expenses ($97 million), Research and developmentexpenses ($62 million) and in Other (income)/deductions - net ($22 million income) for the six months ended July 2, 2006. Included in Cost of sales ($1 million), Selling, informational and administrative expenses ($21 million), and Research and developmentexpenses ($11 million) for the three months and six months ended July 3, 2005.

(h)

Includedprimarily in Other (income)/deductions - net.

(i)

Included in Provision/(benefit)Provision for taxes on income.

FINANCIAL CONDITION, LIQUIDITY AND CAPITAL RESOURCES

Net Financial Assets

Our net financial asset position follows:

(millions of dollars)

July 2,
2006

Dec. 31,
2005

July 1,
2007

Dec. 31,
2006

Financial assets:

Cash and cash equivalents

$

1,921

$

2,247

$

2,138

$

1,827

Short-term investments

12,829

19,979

20,115

25,886

Short-term loans

511

510

540

514

Long-term investments and loans

2,387

2,497

5,067

3,892

Total financial assets

17,648

25,233

27,860

32,119

Debt:

Short-term borrowings

3,779

11,589

Short-term borrowings, including current portion of long-term debt

2,432

2,434

Long-term debt

5,450

6,347

5,777

5,546

Total debt

9,229

17,936

8,209

7,980

Net financial assets

$

8,419

$

7,297

$

19,651

$

24,139

Short-term investments at December 31, 2006, reflects the receipt of proceeds of $16.6 billion from the sale of our Consumer Healthcare business on December 20, 2006.

We rely largely on operating cash flow, short-term investments, long-term debt and short-term commercial paper borrowings and long-term debt to provide for the working capital needs of our operations, including our R&D activities. We believe that we have the ability to obtain both short-term and long-term debt to meet our financing needs for the foreseeable future.

Investments

Our short-term and long-term investments consist primarily of high-quality, liquid investment-grade available-for-sale debt securities. Wherever possible, cash management is centralized and intercompany financing is used to provide working capital to our operations. Where local restrictions prevent intercompany financing, working capital needs are met through operating cash flows and/or external borrowings. Our portfolio of short-term investments at December 31, 2006, reflects the receipt of proceeds from the sale of our Consumer Healthcare business of $16.6 billion. Our portfolio of short-term investments was reduced in the first six monthshalf of 20062007 and the proceeds were primarily used to pay down short-term borrowings.taxes due on the gain from the sale of our Consumer Healthcare business, completed in December 2006, and for share repurchases and dividends in the first six months of 2007.

Long-Term Debt

On February 22, 2006,May 11, 2007, we issued the following Japanese yen fixed-rate bonds,notes to be used for general corporate purposes:

$508 million equivalent, senior unsecured notes, due February 2011, which pay interest semi-annually, beginning on August 22, 2006, at a rate of 1.2%; and

$1.2 billion equivalent, senior, unsecured, euro-denominated notes, due May 15, 2017, which pay interest annually, beginning on May 15, 2008, at a fixed rate of 4.55%.

 

$466 million equivalent, senior unsecured notes, due February 2016, which pay interest semi-annually, beginning on August 22, 2006, at a rate of 1.8%.

The notes were issued under a $5 billion debt shelfnew securities registration statement filed with the SECSecurities and Exchange Commission (SEC) in November 2002. Such yen debt is designated as a hedge of our yen net investments.

In May 2006, we decided to exercise Pfizer's option to call, at par-value plus accrued interest, $1 billion of senior unsecured floating-rate notes, which were included in Long-term debt as of December 31, 2005 and included in Short-term debt as of July 2, 2006. Notice to call was given to the Trustees and the notes were redeemed in the third quarter of 2006.March 2007.

Credit Ratings

Two major corporate debt-rating organizations, Moody's Investors Services (Moody's) and Standard & Poor's (S&P), assign ratings to our short-term and long-term debt. The following chart reflects the current ratings assigned to the Company'sour senior unsecured non-credit enhanced long-term debt and commercial paper issued directly by the Company or by affiliates with a guarantee from the Companyus by each of these agencies:

Long-Term-Debt

Date of

Name of Rating Agency

Commercial Paper

  

Rating

Outlook

Last Action

   

Moody's

P-1

AaaAa1

NegativeStable

December 2006

S&P

A1+

AAA

StableNegative

December 2006

In early April 2005, following the market withdrawal of Bextra and the FDA's decision requiring new labeling for Celebrex, Moody's placed our Aaa rating under review for possible downgrade. The review was completed in June 2005 when Moody's removed Pfizer from review status and reaffirmed our Aaa rating. However, Moody's maintained our rating outlook as negative. Following our announcement in June 2006 of the agreement to sell our Consumer Healthcare business and our target to purchase up to $17 billion of Pfizer stock in 2006 and 2007, Moody's again reaffirmed our Aaa rating with a negative outlook. The negative outlook reflects Moody's overall general negative rating outlook for the major pharmaceutical sector and, specifically, its concern that disappointing product sales, setbacks in development of key pipeline products, or a shift towards a more aggressive financial profile, including an increased pace of share purchase levels, could result in Pfizer's financial metrics falling below those appropriate for a Aaa-rated company.

S&P views our rating outlook as stable, while they note a slowdown in sales and earnings growth as a result of major patent expirations and increased competition. S&P relies on Pfizer's excellent position in the worldwide pharmaceutical market, highlighted by its diverse drug portfolio and deep product pipeline, together with our superior financial profile and cash-generating ability.

Our superior credit ratings are primarily based on our diversified product portfolio, our strong operating cash flow, our substantial financial assets, our strong late-stage product pipeline and our desire to maintain a prudent financial profile. Our access to financing at favorable rates would be affected by a substantial downgrade in our credit ratings.

Debt Capacity

We have available lines of credit and revolving-credit agreements with a group of banks and other financial intermediaries. We maintain cash balances and short-term investments in excess of our commercial paper and other short-term borrowings. AtAs of July 2, 2006,1, 2007, we had access to $3.6 billion of lines of credit, of which $1.1$1.3 billion expire within one year. Of these lines of credit, $3.3$3.4 billion are unused, of which our lenders have committed to loan us $2.1 billion at our request. $2.0 billion of the unused lines of credit, which expire in 2011,2012, may be used to support our commercial paper borrowings.

As of July 2, 2006,In March 2007, we hadfiled a new securities registration statement with the ability to borrow approximately $1 billion by issuing debt securitiesSEC. This registration statement was filed under our existing debtthe automatic shelf registration process available to well-known seasoned issuers and is effective for three years. We can issue securities of various types under that registration statement filed with the SEC in November 2002.

at any time, but subject to indebtedness limitations established from time to time by our Board of Directors.

Goodwill and Other Intangible Assets

AtAs of July 2, 2006, goodwill1, 2007, Goodwill totaled $21.1$21.0 billion (19% of our total assets) and other intangible assets, net of accumulated amortization, totaled $26.1$22.9 billion (23%(21% of our total assets). The largest components of goodwillGoodwill and other intangible assets were acquired in connection with our acquisition of Pharmacia. In the first quarter of 2006, we acquired the sanofi-aventis worldwide rights, including patent rights and production technology, to manufacture and sell Exubera. In connection with the acquisition, we recorded an intangible asset for developed technology rights of approximately $1.0 billion and goodwill of approximately $166 million.Pharmacia Corporation in 2003. Finite-lived intangible assets, net, include $21.8$18.9 billion related to developed technology rights and $814$582 million related to brands. Indefinite-lived intangible assets include $3.0$2.9 billion related to brands.

The developed technology rights primarily represent the amortized acquisition-date fair value of the commercialized products that we acquired from Pharmacia.Pharmacia in 2003. We acquired a well-diversified portfolio of developed technology rights across the therapeutic categories displayed in the table of major Human HealthPharmaceutical products in the "Revenues" section of this MD&A. While the Arthritis and Pain therapeutic category represents about 27%28% of the total value of developed technology rights atas of July 2, 2006,1, 2007, the balance of the value is evenly distributed across the following Human HealthPharmaceutical therapeutic product categories: Ophthalmology; Oncology; Urology; Infectious and Respiratory Diseases; Endocrine Disorders categories; and, as a group, the Cardiovascular and Metabolic Diseases; Central Nervous System Disorders and All Other categories.

SELECTED MEASURES OF LIQUIDITY AND CAPITAL RESOURCES

The following table sets forth certain relevant measures of our liquidity and capital resources:

(millions of dollars, except ratios and per common share data)

July 2,
2006

Dec. 31,
2005

July 1,
2007

Dec. 31,
2006

Cash and cash equivalents and short-term investments and loans

$

15,261

$

22,736

$

22,793

$

28,227

Working capital(a)

$

20,939

$

18,424

$

26,486

$

25,560

Ratio of current assets to current liabilities

2.04:1

1.65:1

2.75:1

2.20:1

Shareholders' equity per common share(b)

$

9.43

$

8.98

$

9.82

$

10.05

    

(a)

Working capital includes assets of discontinued operations and other assets held for sale of $6.8 billion$34 million as of July 1, 2007, and $6.7 billion and$62 million as of December 31, 2006. Working capital also includes liabilities of discontinued operations and other liabilities held for sale of $1.4 billion and $1.2 billion,nil as of July 2, 20061, 2007, and $2 million as of December 31, 2005.2006.

(b)

Represents total shareholders' equity divided by the actual number of common shares outstanding (which excludes treasury shares and those held by our employee benefit trust).

The increaseincreases in working capital and the ratio of current assets to current liabilities, as of July 2, 2006 as1, 2007, compared to December 31, 2005 was2006, were primarily due to:

the reclassification of certain amounts associated with uncertain tax positions (about $4.0 billion) from current to noncurrent upon adoption of a general reduction in payables and accruals of about $1.0 billion, reflecting timing;new accounting standard,

   

an increase in inventories of $914 million, which is primarily due to the acquisition of sanofi-aventis' Exubera inventory, the build-up of inventory in advance of product launches and the impact of foreign exchange;

an increase in net current financial assets of $335 million primarily due to the pay down of short-term borrowings, partially offset by the redemption of short-term investments; and

a decrease in Medicaid rebate and contract rebate accruals of $130 million primarily due to the impact of the Medicare Act;

partially offset by:

the funding of share purchases and dividends in part through the use of the proceeds from the redemption of short-term investments.

   

the expected timing of tax obligations of about $527 million.

Net Cash Provided by Operating Activities

During the first six months of 2006,2007, net cash provided by operating activities was $9.1$4.9 billion, as compared to $7.0$9.1 billion in the same period of 2005.2006. The increasedecrease in net cash provided by operating activities was primarily attributable to:

higher current period income from operations, nettax payments ($2.8 billion) in the first six months of non-cash items,2007, related primarily to the gain on the sale of our Consumer Healthcare business in December 2006; and

   

partially offset by:

the timing of other receipts and payments in the ordinary course of business.lower income from operations.

The

In 2006, the estimated net cash flows provided by operating activities associated with discontinued operations were not significant.

The cash flow line item called Changes in assets and liabilities (net of businesses acquired and divested) in 2007, compared to 2006, primarily reflects higher taxes paid, partially offset by restructuring charges expensed, but not yet paid.

Net Cash Provided by Investing Activities

During the first six months of 2006,2007, net cash provided by investing activities was $4.3$3.5 billion, as compared to $4.2$4.3 billion in the same period in 2005.2006. The increasedecrease in net cash provided by investing activities was primarily attributable to:

higher net redemptions of investments in 2006 (a positive change in cash and cash equivalents of $2.2 billion); in 2006, the proceeds of which were utilized to repay debt and in 2005, the proceeds of which were used to fund the repatriation of foreign earnings as a result of the Jobs Act,

partially offset by:

the acquisition of Rinat and sanofi-aventis' rights to Exubera in 2006 compared to the acquisition of Idun in 2005 (an increased use of cash of $1.7 billion).

Thelower net redemptions of investments in 2007 (a negative change in cash and cash equivalents of $2.2 billion),

partially offset by:

the acquisitions of BioRexis Pharmaceutical Corp. and Embrex, Inc. in 2007, compared to the acquisitions of Rinat and sanofi-aventis' rights associated with Exubera in 2006 (a decreased use of cash of $1.5 billion).

In 2006, the estimated net cash flows used in investing activities associated with discontinued operations were not significant.

Net Cash Used in Financing Activities

During the first six months of 2006,2007, net cash used in financing activities was $13.7$8.2 billion, as compared to $11.7$13.7 billion in the same period in 2005.2006. The increasedecrease in net cash used in financing activities was primarily attributable to:

net borrowings of $498 million in 2007, compared to net repayments of $8.6 billion on total borrowings in 2006, compared to $5.7 billion in 2005, and

an increase in cash dividends paid of $538 million as compared to the first six months of 2005 primarily due to an increase in the dividend rate,

   

partially offset by:

  

lowerhigher purchases of common stock in the first six months2007 of 2006 of$5.0 billion, compared to $2.0 billion as compared to $3.3 billionin 2006; and

an increase in cash dividends paid of $572 million, reflecting an increase in the first six months of 2005.dividend rate partially offset by lower shares outstanding.

The

In 2006, the estimated net cash flows used in financing activities associated with discontinued operations were not significant.

In June 2005, we announced a $5 billion share-purchase program, which is primarily being funded by operating cash flows. Through July 2, 2006, we purchased approximately 102 million shares under that program for approximately $2.5 billion.flows and a portion of the proceeds from the sale of our Consumer Healthcare business. In June 2006, the Board of Directors increased our share-purchase authorization from $5 billion to $18 billion.

In October 2004, we announced a $5 billion share-purchase program, which we completed in During the second quarterfirst six months of 2005 and was funded from operating cash flows. In total, under the October 2004 program,2007, we purchased approximately 185190 million shares.shares under that program for approximately $5.0 billion.

Contractual Obligations

The contractual obligations table as of December 31, 2006, included in the "Financial Review" section of our 2006 Financial Report did not reflect amounts associated with uncertain tax positions. As a result of the adoption as of January 1, 2007, of Financial Accounting Standards Board (FASB) Interpretation No. 48 (FIN 48), Accounting for Uncertainty in Income Taxes, aninterpretation of SFAS 109, Accounting for Income Taxes, and supplemented by FASB Financial Staff Position FIN 48-1, Definition of Settlement in FASB Interpretation No. 48, issued May 2, 2007(see Notes to Condensed Consolidated Financial Statements-Note 2. Adoption of New Accounting Policy), our disclosure of contractual obligations will now include information concerning uncertain tax positions. As of July 1, 2007, there have been no significant changes in our contractual obligations. Except for amounts reflected in Income taxes payable, we are unable to predict the timing of tax settlements as tax audits can involve complex issues and the resolution of those issues may span multiple years, particularly if subject to negotiation or litigation.

OFF-BALANCE SHEET ARRANGEMENTS

In the ordinary course of business and in connection with the sale of assets and businesses, we often indemnify our counterparties against certain liabilities that may arise in connection with a transaction or related to activities prior to a transaction. These indemnifications typically pertain to environmental, tax, employee and/or product-related matters, and patent infringement claims. If the indemnified party were to make a successful claim pursuant to the terms of the indemnification, we would be required to reimburse the loss. These indemnifications are generally subject to threshold amounts, specified claim periods and other restrictions and limitations. Historically, we have not paid significant amounts under these provisions and, as of July 2, 2006,1, 2007, recorded amounts for the estimated fair value of these indemnifications are not significant.

Certain of our co-promotion or license agreements give our licensors or partners the rights to negotiate for, or in some cases to obtain, under certain financial conditions, co-promotion or other rights in specified countries with respect to certain of our products.

RECENTLY ADOPTEDNEW ACCOUNTING STANDARDS

OnRecently Adopted Accounting Standards

As of January 1, 2006,2007, we adopted the provisions of Statement of Financial Accounting Standards (SFAS) No. 123R, Share-Based Payment, as supplemented by the guidance provided by Staff Accounting Bulletin (SAB) 107, issued in March 2005. (SFAS 123R replaces SFAS 123, Stock-Based Compensation, issued in 1995.) (See Notes to Condensed Consolidated Financial Statements - Note 4, Adoption of New Accounting Standards, and Note 14, Share-Based Payments).

RECENTLY ISSUED ACCOUNTING STANDARDS

In June 2006, the FASB issued Interpretation No. 48 (FIN 48), Accounting for Uncertainty in Income Taxes, an interpretation of  SFAS 109, Accounting for Income Taxes. FIN 48, which provides guidance relative toon the recognition, derecognition and measurement of tax positions for financial statement purposes. ThePrior to 2007, our policy had been to account for income tax contingencies based on whether we determined our tax position to be 'probable' under current tax law of being sustained, as well as an analysis of potential outcomes under a given set of facts and circumstances. FIN 48 requires that tax positions be sustainable based on a 'more likely than not' standard also requires expanded disclosures.of benefit recognition under current tax law, and adjusted to reflect the largest amount of benefit that is greater than 50% likely of being realized upon settlement, presuming that the tax position is examined by the appropriate taxing authority that has full knowledge of all relevant information. As a result of the implementation of FIN 48, we reduced our existing liabilities for uncertain tax positions by approximately $11 million, which has been recorded as a direct adjustment to the opening balance of Retained earnings, and changed the classification of virtually all amounts associated with uncertain tax positions, including the associated accrued interest, from current to noncurrent, as of the date of adoption.

Recently Issued Accounting Standards, Not Adopted as of July 1, 2007

In September 2006, the Financial Accounting Standards Board issued Statement of Financial Accounting Standards (SFAS) No. 157, Fair Value Measurements. SFAS 157 provides guidance for, among other things, the definition of fair value and the methods used to measure fair value. The provisions of FIN 48SFAS 157 are effective for fiscal years beginning after DecemberNovember 15, 2006. The Company is currently2007. We are in the process of evaluating the impact on the financial statements of adopting FIN 48.SFAS 157 on our financial statements.

In June 2007, the Emerging Issues Task Force (EITF) issued EITF Issue No. 07-3, Accounting for Nonrefundable Advance Payments for Goods or Servicesto be Used in Future Research and Development Activities. EITF Issue No. 07-3 provides guidance concerning the accounting for non-refundable advance payments for goods and services that will be used in future R&D activities and requires that they be expensed when the research and development activity has been performed and not at the time of payment. The provisions of EITF Issue No. 07-3 are effective for the fiscal years beginning after December 15, 2007, with a cumulative-effect adjustment to Retained Earnings as of the beginning of the year of adoption. We are in the process of evaluating the impact of adopting EITF Issue No. 07-3 on our financial statements.

OUTLOOK

ResultsAt current exchange rates, we expect 2007 revenues of $47 billion to $48 billion, reported diluted EPS of $1.30 to $1.41 and Adjusted diluted EPS of $2.08 to $2.15. This forecast reflects an adverse court decision which resulted in 2006 have been, and will continue to be, impacted by the loss of U.S. exclusivity for Norvasc six months earlier than expected; higher than previously anticipated favorability of certain keyforeign exchange resulting from the further weakness of the dollar relative to various other currencies; and a range of variability in the performance of our products, sinceincluding Lipitor, Exubera and Chantix.

We have incorporated into our current forecast for full-year 2007 worldwide Lipitor revenues a moderation in the beginninglevel of 2004. Revenues also have been,decline of prescriptions in the U.S. market relative to the second quarter of 2007, reflecting extensive promotional and may continue to be, impacted by uncertainty related to selective COX-2 inhibitors,contracting efforts, as well as lower prescription growth or increased competition in key marketsan increase in the U.S. Second quarter 2006 results reflect a solid operating performancelevel of contracting rebates consistent with robust revenue growth of many key in-line and new products, further leveraged by tempered operating expenses in Adjusted income. Second-quarter and year-to-date results benefited as well from a number of seasonalization factors, including the impact of production variances and geographic mix on cost of sales, the timing of promotional expenditures for new-product launches and of expenditures for research and development programs, as well as the effective tax rate.  In the second half of 2006, some of these factors are expected to reverse direction.

The anticipated growth of four products--Lipitor, Celebrex, Lyrica and Geodon--is expected to contribute significantly to our 2006 revenues.current, more flexible contracting strategy. At current exchange rates, we are targeting achievementnow expect full-year 2007 worldwide Lipitor revenues of flat to a 5% decline relative to 2006.

At current exchange rates, we forecast 2008 revenues of $46.5 billion to $48.5 billion, reported diluted EPS of $1.75 to $1.93 and Adjusted diluted EPS of $2.31 to $2.45. This forecast reflects a residual adverse impact next year from the loss of U.S. exclusivity for Norvasc in March 2007; heightened uncertainty regarding patent protection for Lipitor in Canada as the result of an adverse lower-court decision, which we have appealed; higher than previously anticipated favorability of foreign exchange, resulting from the further weakness of the dollar relative to various other currencies; the recent FDA approval of a fibromyalgia indication for Lyrica; and a range of variability in the performance of our revenue goals for these four products, including Lipitor, Exubera and continue toChantix.

At current exchange rates, we expect 2006 aggregate revenues to be comparable to overall revenues in 2005. We are targeting Lipitor sales of about $13 billion this year, although it is an ambitious goal in light of the recent introduction of generic simvastatin in the U.S., as well as other competitive pressures. New clinical data, educational campaigns on Lipitor that highlight its strong benefit profile and advantageous formulary positioning are expected to contribute to growth. We continue to expect full-year Celebrex revenues of at least $2 billion, although it is an ambitious target given the ongoing pressures in the arthritis market. Celebrex remains an important treatment option for millions of arthritis patients. In the first six months of 2006, Geodon delivered excellent results and we continue to expect full-year Geodon revenues of about $800 million. Lyrica has exceeded our high initial expectations and we now expect Lyrica revenues to be more than $1 billion in 2006. The contribution of new products is expected to continue to accelerate as we launch new products throughout the year.

We expect our cash flow from operations of $12 billion to exceed $16$13 billion in 2006. Our expected cash flow from operations over the next 30 months2007 and the expected after-tax proceeds from the sale of our Consumer Healthcare business of about $13.5$18 billion will together amount to approximately $34$19 billion after capital expenditures and dividends.in 2008. We have allocated about $17 billion of these resources for the possible acquisition of products and technologies that will drive long-term growth of the business. Further, wecontinue to expect to purchase up to $7$10 billion of our stock in 2006 and up to an additional $10 billion in 2007 under our recently expanded share-purchase program.

We At current exchange rates, we now anticipate that the SI&A pre-tax component of Adjusted income will approximate $15.2 billion this year. Absent the impact of foreign exchange, we continue to target, and are on track to achieve, a year-over-year absolute reduction of more than $500 million in the SI&A pre-tax component of Adjusted income associated with our efforts to restructure our cost base. In 2008, at current exchange rates, we continue to expect AtS-related cost savings in excessto achieve an absolute net reduction of $2 billion in 2006, an increasethe pre-tax total expense component of Adjusted income of at least $1.2$1.5 billion over 2005 savings.to $2.0 billion, compared to 2006. (For an understanding of Adjusted income, see the "Adjusted Income" section of this MD&A.)

"Current exchange rates", as referenced in this Outlook section, is defined as rates approximating foreign currency spot rates at the end of our second quarter for international operations (May 2007).

Given these and other factors, a reconciliation, at current exchange rates and reflecting management's current assessment for 2006,2007 and 2008, of forecasted 20062007 and 2008 Adjusted income and Adjusted diluted EPS to forecasted 20062007 and 2008 reported Net income and reported diluted EPS, follows:

($ billions, except per-share amounts)

Net Income(a)

Diluted EPS(a)

Full-Year 2007 Forecast

Full-Year 2008 Forecast

($ billions, except per share amounts)

  

Net Income(a)

  

Diluted EPS(a)

  

Net Income(a)

  

Diluted EPS(a)

Forecasted Adjusted income/diluted EPS(b)

~$14.7     

~$2.00     

~$

14.5-$15.0

~$

2.08-$2.15

~$

15.6-$16.6

~$

2.31-$2.45

Purchase accounting impacts, net of tax(b)

(2.9)    

(0.40)    

(2.7)

(0.39)

(2.0)

(0.30)

Adapting to scale costs, net of tax

(1.1)    

(0.15)    

(2.5-2.7)

(0.35-0.39)

(1.5-1.8)

(0.22-0.26)

Income from discontinued operations, net of tax(c)

0.5     

0.07     

Equity sales/other

0.2     

0.02     

Resolution of certain tax positions

0.4     

0.06     

Forecasted reported Net income/diluted EPS

~$11.8     

~$1.60     

~$

9.1-$9.8

~$

1.30-$1.41

~$

11.8-$13.1

~$

1.75-$1.93

   

(a)

Includes the Consumer Healthcare business as discontinued operations and excludesExcludes the effects of other business-development transactions not completed as of the endof the second quarter of 2006 and the potential impact from a substantial prospective gain on the divestiture of Pfizer Consumer Healthcare.July 1, 2007.

(b)

Increase in purchase accounting impacts versusFor an understanding of Adjusted income, see the prior estimate reflects Merger-related in-process research and development charges associated primarily with the Rinat acquisition.

(c)

Primarily reflects the reclassification"Adjusted Income" section of Pfizer Consumer Healthcare to discontinued operations.this MD&A.

Our forecasted financial performance in 20062007 and 2008 is subject to a number of factors and uncertainties--as described in the "Forward Looking"Forward-Looking Information and Factors That May Affect Future Results" section below. Some of these factors and uncertainties may persist over our planning horizon.

FORWARD-LOOKING INFORMATION AND FACTORS THAT MAY AFFECT FUTURE RESULTS

Our disclosureThe Securities and analysis in this report, including but not limitedExchange Commission encourages companies to the information discussed in the Outlook section above, containdisclose forward-looking information about our Company's financialso that investors can better understand a company's future prospects and make informed investment decisions. This report and other written or oral statements that we make from time to time contain such forward-looking statements that set forth anticipated results based on management's plans and estimates, business prospects, in-line products and product candidates thatassumptions. Such forward-looking statements involve substantial risks and uncertainties, including, without limitation, information about the Company's agreementuncertainties. We have tried, wherever possible, to sell its Consumer Healthcare business to Johnson & Johnson and the use of sale proceeds, as well as about the Company's stock-purchase plans. From time to time, we also may provide oral or written forward-looking statements in other materials we release to the public. Forward-looking statements give our current expectations or forecasts of future events. You can identify thesesuch statements by the fact that they do not relate strictly to historic or current facts. They useusing words such as "will," "anticipate," "estimate," "expect," "project," "intend," "plan," "believe," "target," "forecast" and other words and terms of similar meaning in connection with any discussion of future operating or financial performance or business plans and prospects. In particular, these include statements relating to future actions, business plans and prospects, prospective products or product approvals, future performance or results of current and anticipated products, sales efforts, expenses, interest rates, foreign exchange rates, the outcome of contingencies, such as legal proceedings, and financial results. Among the factors that could cause actual results to differ materially are the following:

theThe success of research and development activities;

  

decisionsDecisions by regulatory authorities regarding whether and when to approve our drug applications as well as their decisions regarding labeling and other matters that could affect the availability or commercial potential of our products;

  

theThe speed with which regulatory authorizations, pricing approvals and product launches may be achieved;

  

competitive developments affecting our current growth products;The success of external business development activities;

  

theCompetitive developments, including with respect to competitor drugs and drug candidates that treat diseases and conditions similar to those treated by our in-line drugs and drug candidates;

The ability to successfully market both new and existing products domestically and internationally;

  

difficultiesDifficulties or delays in manufacturing;

  

tradeTrade buying patterns;

    

theThe ability to meet generic and branded competition after the loss of patent protection for our products and competitor products;

  

theThe impact of existing and future regulatory provisions on product exclusivity;

  

trendsTrends toward managed care and healthcare cost containment;

  

possible U.S. legislation or regulatory action affecting, among other things, pharmaceutical product pricing, and reimbursement or access, including under Medicaid and Medicare, the importation of prescription drugs that are marketed from outside the U.S. and sold at prices that are regulated by governments of various foreign countries, and the involuntary approval of prescription medicines for over-the-counter use;

  

the potentialThe impact of the Medicare Prescription Drug, Improvement and Modernization Act of 2003;

  

legislationLegislation or regulationsregulatory action in markets outside the U.S. affecting pharmaceutical product pricing, reimbursement or access;

  

contingenciesContingencies related to actual or alleged environmental contamination;

  

claimsClaims and concerns that may arise regarding the safety or efficacy of in-line products and product candidates;

  

legalLegal defense costs, insurance expenses, settlement costs and the risk of an adverse decision or settlement related to product liability, patent protection, governmental investigations, ongoing efforts to explore various means for resolving asbestos litigation and other legal proceedings;

   

theThe Company's ability to protect its patents and other intellectual property both domestically and internationally;

  

interestInterest rate and foreign-currency exchange-rateforeign currency exchange rate fluctuations;

  

governmentalGovernmental laws and regulations affecting domestic and foreign operations, including tax obligations;

  

changesChanges in U.S. generally accepted accounting principles;

   

anyAny changes in business, political and economic conditions due to the threat of future terrorist activity in the U.S. and other parts of the world, and related U.S. military action overseas;

     

growthGrowth in costs and expenses;

  

changesChanges in our product, segment and geographic mix; and

  

theThe impact of acquisitions, divestitures, restructurings, product withdrawals and other unusual items, including our ability to realize the projected benefits of our Adapting to Scale multi-year productivity initiative, andincluding the abilityprojected benefits of the Company and Johnson & Johnson to satisfybroadening of this initiative over the conditions to closing the sale of the Company's Consumer Healthcare business, including receiving the required regulatory approvals.next few years.

We cannot guarantee that any forward-looking statement will be realized, although we believe we have been prudent in our plans and assumptions. Achievement of futureanticipated results is subject to substantial risks, uncertainties and inaccurate assumptions. Should known or unknown risks or uncertainties materialize, or should underlying assumptions prove inaccurate, actual results could differvary materially from past results and those anticipated, estimated or projected. Investors should bear this in mind as they consider forward-looking statements.

We undertake no obligation to publicly update forward-looking statements, whether as a result of new information, future events or otherwise. You are advised, however, to consult any further disclosures we make on related subjects in our Forms 10-Q, 8-K and 10-K reports to the Securities and Exchange Commission. Our Form 10-K filing for the 20052006 fiscal year listed various important factors that could cause actual results to differ materially from expected and historic results. We note these factors for investors as permitted by the Private Securities Litigation Reform Act of 1995. Readers can find them in Part I, Item 1A, of that filing under the heading "Risk Factors and Cautionary Factors That May Affect Future Results." We incorporate that section of that Form 10-K in this filing and investors should refer to it. You should understand that it is not possible to predict or identify all such factors. Consequently, you should not consider any such list to be a complete set of all potential risks or uncertainties.

This report includes discussion of certain clinical studies relating to various in-line products and/or product candidates. These studies typically are part of a larger body of clinical data relating to such products or product candidates, and the discussion herein should be considered in the context of the larger body of data.

Legal Proceedings and Contingencies

We and certain of our subsidiaries are involved in various patent, product liability, consumer, commercial, securities environmental and taxenvironmental litigations and claims; government investigations; and other legal proceedings that arise from time to time in the ordinary course of our business. We do not believe any of them will have a material adverse effect on our financial position.

We record accruals for such contingencies to the extent that we conclude their occurrence is probable and the related damages are estimable. If a range of liability is probable and estimable and some amount within the range appears to be a better estimate than any other amount within the range, we accrue that amount. If a range of liability is probable and estimable and no amount within the range appears to be a better estimate than any other amount within the range, we accrue the minimum of such probable range. Many claims involve highly complex issues relating to causation, label warnings, scientific evidence, actual damages and other matters. Often these issues are subject to substantial uncertainties and, therefore, the probability of loss and an estimation of damages are difficult to ascertain. Consequently, we cannot reasonably estimate the maximum potential exposure or the range of possible loss in excess of amounts accrued for these contingencies. These assessments can involve a series of complex judgments about future events and can rely heavily on estimates and assumptions. Our assessments are based on estimates and assumptions that have been deemed reasonable by management. Litigation is inherently unpredictable, and excessive verdicts do occur. Although we believe we have substantial defenses in these matters, we could in the future incur judgments or enter into settlements of claims that could have a material adverse effect on our results of operations in any particular period.

Patent claims include challenges to the coverage and/or validity of our patents on various products or processes. Although we believe we have substantial defenses to these challenges with respect to all our material patents, there can be no assurance as to the outcome of these matters, and a loss in any of these cases could result in a loss of patent protection for the drug at issue, which could lead to a significant loss of sales of that drug and could materially affect future results of operations.

Item 3.  Quantitative and Qualitative Disclosures About Market Risk.

Information required by this item is incorporated by reference from the discussion under the heading Financial Risk Management in our 20052006 Financial Report, which is filed as exhibitExhibit 13 to our 20052006 Form 10-K.

In addition, we entered into an interest rate swap to effectively convert the fixed rate associated with the long-term euro-denominated notes issued on May 11, 2007, to a floating rate. We currently invest and borrow primarily onalso entered into a short-term or effectively variable-rate basis.currency swap to offset the foreign exchange effects of the remeasurement of those euro-denominated notes. This currency swap is not designated as a hedge, but serves to economically limit our foreign exchange risk.

Item 4.  Controls and Procedures.

As of the end of the period covered by this report, we carried out an evaluation, under the supervision and with the participation of our principal executive officer and principal financial officer, of the effectiveness of the design and operation of our disclosure controls and procedures (as such term is defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of 1934 (the Exchange Act)). Based on this evaluation, our principal executive officer and principal financial officer concluded that our disclosure controls and procedures are effective in alerting them in a timely manner to material information required to be disclosed in our periodic reports filed with the SEC.

During our most recent fiscal quarter, there has not beenoccurred any change in our internal control over financial reporting (as such term is defined in Rules 13a-15(f) and 15d-15(f) under the Exchange Act) that has materially affected, or is reasonably likely to materially affect, our internal control over financial reporting. However, we do wish to highlight some changes which, taken together, are expected to have a favorable impact on our controls over a multi-year period. We continue to pursue a multi-year initiative to outsource some transaction-processing activities within certain accounting processes and are migrating to a consistent enterprise resource planning system across the organization. These are enhancements of on-goingongoing activities to support the growth of our financial shared service capabilities and standardize our financial systems. None of these initiatives is in response to any identified deficiency or weakness in our internal control over financial reporting.

PART II - OTHER INFORMATION

Item 1.  Legal Proceedings

Certain legal proceedings in which we are involved are discussed in Note 1819 to the consolidated financial statements included in our 20052006 Financial Report; Part I, Item 3, of our Annual Report on Form 10-K for the year ended December 31, 2005;2006; and Part II, Item 1, of our Quarterly Report on Form 10-Q for the quarter ended April 2, 2006.1, 2007. The following discussion is limited to certain recent developments concerning our legal proceedings and should be read in conjunction with those earlier Reports. Unless otherwise indicated, all proceedings discussed in those earlier Reports remain outstanding. Reference also is made to the Legal Proceedings and Contingencies section in Part I, Item 2, of this Form 10-Q.

Patent Matters

Norvasc (amlodipine)

Amlodipine besylate is the salt form contained in Norvasc. As previously reported, between January 2006 and February 2007, three different federal District Courts held that our amlodipine besylate patent is valid and infringed by Torpharm/Apotex, Synthon Pharmaceuticals, Inc. and Mylan Pharmaceuticals, Inc., respectively.

Each of these decisions was appealed to the U.S. Court of Appeals for the Federal Circuit. In March 2007, a panel of the Federal Circuit reversed the District Court's decision in the action against Torpharm/Apotex, which was the first of these actions to go to trial, and held that our amlodipine besylate patent is invalid. In May 2007, the full U.S. Court of Appeals for the Federal Circuit denied our request to review the panel's decision. In June 2007, the U.S. Supreme Court denied our request to recall or stay the panel's decision.

On March 23, 2007, Mylan launched its own generic amlodipine besylate product and, in response, we launched our own generic amlodipine besylate product through Pfizer's Greenstone subsidiary. Subsequently, various other generic manufacturers have launched their own generic amlodipine besylate products.

Lipitor (atorvastatin)

As previously reported, in April 2007, Teva Pharmaceuticals USA, Inc. notified us that it had filed an abbreviated new drug application with the FDA seeking approval to market a generic version of Lipitor. Teva asserts the invalidity of our enantiomer patent which, including the six-month pediatric exclusivity period, expires in June 2011, and the non-infringement of certain later-expiring patents. In June 2007, we filed suit against Teva in the U.S. District Court for the District of Delaware asserting the validity and infringement of the enantiomer patent. Teva did not challenge our basic patent which, including the six-month pediatric exclusivity period, expires in March 2010.

In July 2007, a law firm that has represented Ranbaxy Pharmaceuticals Inc. in Lipitor patent litigation filed a request for a reexamination of our basic Lipitor patent with the U.S. Patent and Trademark Office (the Patent Office). The Patent Office first will determine whether it will grant the request; it is not unusual for such requests to be granted. If the Patent Office grants the request, it then will reexamine the patent on the merits.

Product Liability Matters

Asbestos

As previously reported, with regard to the Chapter 11 bankruptcy case involving Quigley Company, Inc. (Quigley), a wholly owned subsidiary, was acquired by Pfizer in 1968 and sold small amounts of products containing asbestos until the early 1970s. In September 2004, Pfizer and Quigley took steps that were intended to resolve all pending and future claims against Pfizer and Quigley in which the claimants allege personal injury from exposure to Quigley products containing asbestos, silica or mixed dust. We took a charge of $369 million, pre-tax ($229 million, after-tax) to third-quarter 2004 earnings in connection with these matters.

In September 2004, Quigley filed a petition in the U.S. Bankruptcy Court for the Southern District of New York seeking reorganization under Chapter 11 of the U.S. Bankruptcy Code. In March 2005, Quigley filed a reorganization plan in the Bankruptcy Court that needed the approval of both the Bankruptcy Court and the U.S. District Court for the Southern District of New York after receipt of the favorable vote of 75% of the claimants. In connection with that filing, Pfizer entered into settlement agreements with lawyers representing more than 80% of the individuals with claims related to Quigley products against Quigley and Pfizer. The agreements provide for a total of $430 million in payments, of which $215 million became due in December 2005 and is being paid to claimants upon receipt by the Company of certain required documentation from each of the claimants. The reorganization plan provided for the establishment of a Trust for the payment of all remaining pending claims as well as any future claims alleging injury from exposure to Quigley products.

As certified by the balloting agent in May 2006, more than 75% of Quigley's claimants holding claims that represent more than two-thirds in value of claims against Quigley voted to accept Quigley's plan of reorganization. On August 9, 2006, in reviewing the voting tabulation methodology, the Bankruptcy Court ruled that certain votes that accepted the plan were not predicated upon the actual value of the claim. As a result, the reorganization plan was not accepted.

In June 2007, Quigley can adjust certain provisions in itsfiled an amended plan of reorganization plan and the voting proceduresthat is intended to conform withaddress the Bankruptcy Court's ruling, and then possibly re-solicitconcerns regarding the voting tabulation methodology. In addition, Pfizer entered into an agreement with the representative of future claimants that provides for the contribution by Pfizer to the Trust of an additional amount with a present value of $88.4 million.

The Bankruptcy Court held a hearing to consider the adequacy of Quigley's disclosure statement on July 12, 2007. If the disclosure statement is approved, Quigley intends to solicit its amended reorganization plan for acceptance or seek alternative remedies. These and other options are being considered.

acceptance. If approved by the claimants and the courts, the amended reorganization plan will resolveresult in a permanent injunction directing all pending and future asbestos claims against Quigley and Pfizer in which claimants allegealleging personal injury from exposure to Quigley products.products to the Trust.

Patent MattersTrovan

Lipitor (atorvastatin)

As previously reported, in 2003, weIn May 2007, the Attorney General of the Federation of Nigeria filed suitcivil and criminal actions in the Federal High Court in Abuja against Pfizer, one of our Nigerian subsidiaries, and several current and former U.S. District Court forand Nigerian employees, including a current Pfizer director.  Also in May 2007, the District of Delaware against Ranbaxy Laboratories Limited for infringement of both our basic product patent for atorvastatin and our patent covering the active enantiomeric formAttorney General of the drug. Our basic product patent, includingState of Kano, Nigeria, filed substantially similar civil and criminal actions in the additional six-month pediatric exclusivity period, expires in March 2010. Our enantiomer patent, including the additional six-month pediatric exclusivity period, expires in June 2011.

In late 2005, the District Court held that both patents are valid and infringed by Ranbaxy's generic atorvastatin product. In August 2006, a panel of the U.S. Court of Appeals for the Federal Circuit affirmed the District Court's decision with respect to our basic product patent. Subject to a possible request for a review by the full U.S. Court of Appeals for the Federal Circuit or an appeal to the U.S. Supreme Court by Ranbaxy, this decision prevents Ranbaxy from marketing a generic version of atorvastatin before March 2010.

The panel also ruled that one of the claims of our enantiomer patent is invalid on technical grounds. We are considering the possibility of seeking a review of the decision regarding our enantiomer patent by the full U.S. Court of Appeals for the Federal Circuit. In addition, the U.S. Patent and Trademark Office has a process for correcting technical defects in patents, and we plan to pursue that process with regard to our enantiomer patent.

As previously reported, in October 2005, in an action brought by Ranbaxy, the United Kingdom's High Court of Justice upheld our basic U.K. patentKano State against substantially the same group of defendants. These actions arise out of a 1996 pediatric clinical study of Trovan, an antibiotic then in late-stage development, that was conducted during a severe meningitis epidemic in Kano. The actions allege, among other things, that the study was conducted without proper government authorization and without the informed consent of the parents or guardians of the study participants and resulted in injury or death to a number of study participants. In the civil actions, the federal government is seeking $6.95 billion in damages and the Kano state government is seeking $2.075 billion in damages for, Lipitor, which expiresamong other things, the costs incurred to provide treatment, compensation and support for the alleged victims and their families; the costs of unrelated health initiatives that failed, allegedly due to societal misgivings attributable to the Trovan study; and general damages. We intend to vigorously defend these actions on the grounds that the 1996 Trovan clinical study was conducted with the full knowledge of the Nigerian federal government and the Kano state government, with the informed consent of the parents or guardians of the study participants, in November 2011, but ruleda responsible and ethical way consistent with the Company's long-standing and abiding commitment to patient care, and that it helped save the lives of children.

The federal civil case against Pfizer and the other defendants was voluntarily withdrawn by Nigerian federal authorities as of July 6, 2007. Various media reports, however, have indicated that a second patent coveringnew civil action, presumably against Pfizer and the calcium saltother defendants, will be filed containing additional allegations.

The 1996 Trovan clinical study has also been the subject of atorvastatin, which expires in July 2010, is invalid. In June 2006, the United Kingdom's Court of Appeal affirmed the lower court's decision. The ruling by the Court of Appeal prohibits Ranbaxy from marketing a generic version of atorvastatin in the U.K. before the expiration of our basic patent in November 2011, subject to a possible further appeal to the House of Lords.

Norvasc (amlodipine)

Synthon Pharmaceuticals, Inc. hastwo civil lawsuits filed an action against us in the U.S. District Court for the Eastern District of Virginia alleging that our sales of Norvasc and Caduet infringe Synthon's patent relating to the manufacture of amlodipine.

Exubera

In August 2006, Novo Nordisk filed an action against usPfizer in the U.S. District Court for the Southern District of New York on behalf of the study participants. The District Court dismissed both cases in 2005 and those decisions are on appeal to the U.S. Court of Appeals for the Second Circuit.

Consumer and Commercial Matters

Neurontin

As previously reported, a number of lawsuits, including purported class actions, have been filed against us in various federal and state courts alleging claims arising from the promotion and sale of Neurontin. The plaintiffs in the purported class actions seek to represent nationwide and certain statewide classes consisting of persons, including individuals, health insurers, employee benefit plans and other third-party payers, who purchased or reimbursed patients for the purchase of Neurontin that allegedly was used for indications other than those included in the product labeling approved by the FDA. In October 2004, many of the suits pending in federal courts, including individual actions as well as purported class actions, were transferred for consolidated pre-trial proceedings to a Multi-District Litigation (In re Neurontin Marketing, Sales Practices and Product Liability Litigation MDL-1629) in the U.S. District Court for the District of Massachusetts. Purported class actions also have been filed against us in various Canadian provincial courts alleging claims arising from the promotion and sale of Neurontin.

In June 2007, a Pennsylvania state court certified a class of all individuals in Pennsylvania who allegedly purchased Neurontin for "off-label" uses from 1995 to the present. The plaintiffs seek a refund of amounts paid by class members for Neurontin. Prior to the ruling in Pennsylvania, state courts in New York and New Mexico declined to certify statewide classes of Neurontin purchasers.

In the Multi-District Litigation, the U.S. District Court for the District of Massachusetts has taken under advisement a motion to certify a nationwide class of consumers and third-party payers who allegedly purchased or reimbursed patients for the purchase of Neurontin for "off-label" uses from 1994 through 2004. Plaintiffs are also seeking certification of a statewide class of purchasers in an action pending in a Kansas state court and a provincewide class in an action pending in Ontario, Canada.

Celebrex and Bextra Matters

As previously reported, beginning in late 2004, actions, including purported class and shareholder derivative actions, relating to Celebrex and Bextra have been filed in various federal and state courts against Pfizer, Pharmacia and certain current and former officers, directors and employees of Pfizer and Pharmacia. These actions include a purported federal shareholder derivative action and certain purported state shareholder derivative actions alleging that our salescertain of Exubera infringe Novo Nordisk's patents relatingPfizer's current and former officers and directors breached fiduciary duties by causing Pfizer to inhaled insulinmisrepresent the safety of Celebrex and, methodsin certain of administrationthe cases, Bextra. On July 17, 2007, the U.S. District Court for the Southern District of inhaled insulin.New York dismissed the purported federal shareholder derivative action . Plaintiffs sought leave of the Court to file an amended complaint, which request was denied by the Court on August 1, 2007.

Tax Matters

On January 25, 2006,The United States is one of our major tax jurisdictions and the Company was notified by the IRS Appeals Division that a resolution had been reached on the matter that we were in the process of appealing related to the tax deductibility of a breakup fee paid by Warner-Lambert Company in 2000. As a result, in the first six months of 2006 we recorded a tax benefit of approximately $441 million related to the resolution of this issue.  

In the second quarter of 2005, we recorded a tax benefit of $586 million primarily related to the resolution of certain tax positions.

The IRS is currently conducting audits of the Pfizer Inc. tax returns for the years 2002, 2003 and 2004. The 2005, 2006 and 20062007 tax years are also currently under audit underas part of the IRS Compliance Assurance Process (CAP), a recently introduced real-time audit process.

All other tax years in the U.S. for Pfizer Inc. are closed under the statute of limitations. With respect to Pharmacia Corporation, the IRS has completed audits of the tax returns for the years 2000 through 2002 and is currently conducting an audit for the year 2003 through the date of the merger with Pfizer (April 16, 2003). Although the U.S. audits for Pharmacia Corporation for all previous years have been closed, tax years 2000 through 2002 are still open under the statute of limitations. In addition to the open audit years in the U.S., we have open audit years in other major tax jurisdictions, such as Canada (1998-2006), Japan (2004-2006), Europe (1996-2006, primarily reflecting Ireland, the U.K., France, Italy, Spain and Germany), and Puerto Rico (2002-2006).

We periodically reassessregularly reevaluate our tax positions and the likelihood of assessmentsassociated interest and penalties, if applicable, resulting from audits of federal, state and foreign income tax filings.filings, as well as changes in tax law that would either increase or decrease the technical merits of a position relative to the more likely than not standard. We believe that our accruals for tax liabilities are adequate for all open years. Many factors are considered in making these evaluations, including past history, recent interpretations of tax law, and the specifics of each matter. Because tax regulations are subject to interpretation and tax litigation is inherently uncertain, these evaluations can involve a series of complex judgments about future events and can rely heavily on estimates and assumptions. Our evaluations are based on estimates and assumptions that have been deemed reasonable by management. However, if our estimates and assumptions are not representative of actual outcomes, our results could be materially impacted.

Item 1A.  Risk Factors.

There have been no material changes from the risk factors disclosed in Part 1, Item 1A, of our 20052006 Form 10-K.

Item 2.  Unregistered Sales of Equity Securities and Use of Proceeds.

This table provides certain information with respect to our purchases of shares of Pfizer's common stock during the three months ended July 2, 2006:fiscal second quarter of 2007:

Issuer Purchases of Equity Securities(a)

Issuer Purchases of Equity Securities(a)

Issuer Purchases of Equity Securities(a)

Period

Total Number of    
Shares Purchased
(b)

Average Price    
Paid per Share
(b)

Total Number of  
Shares Purchased as  
Part of Publicly  
Announced Plan
(a)

Approximate Dollar  
Value of Shares that  
May Yet Be Purchased  
Under the Plan
(a)

Total Number of    
Shares Purchased
(b)

Average Price    
Paid per Share
(b)

Total Number of  
Shares Purchased as  
Part of Publicly  
Announced Plan
(a)

Approximate Dollar  
Value of Shares that  
May Yet Be Purchased  
Under the Plan
(a)

April 3, 2006 through
April 30, 2006

1,706,850    

$24.77    

1,694,000  

$  3,464,989,094  

May 1, 2006 through
May 31, 2006

19,479,336    

$24.77    

19,378,700  

$  2,985,002,751  

June 1, 2006 through
July 2, 2006

20,397,319    

$23.43    

20,391,300  

$15,507,212,045  

April 2, 2007, through
April 30, 2007

26,982,006    

$26.29    

26,927,114  

$7,320,578,466  

May 1, 2007, through
May 31, 2007

33,879,656    

$27.09    

33,835,372  

$6,404,030,663  

June 1, 2007, through
July 1, 2007

35,930,510    

$26.62    

32,971,400  

$5,529,240,862  

Total

41,583,505    

$24.11    

41,464,000  

96,792,172    

$26.69    

93,733,886  

  

(a)

On June 23, 2005, Pfizer announced that the Board of Directors authorized a $5 billion share-purchase plan (the "2005 Stock Purchase Plan"). On June 26, 2006, Pfizer announced that the Board of Directors increased the authorized amount of shares to be purchased under the 2005 Stock Purchase Plan from $5 billion to $18 billion.

 

    

(b)

In addition to purchases under the 2005 Stock Purchase Plan, this columnthese columns reflects the following transactions during the three months ended July 2, 2006:fiscal second quarter of 2007: (i) the deemed surrender to Pfizer of 26,58092,810 shares of common stock to pay the exercise price and to satisfy tax withholding obligations in connection with the exercise of employee stock options, (ii) the open-market purchase by the trustee of 83,89191,504 shares of common stock in connection with the reinvestment of dividends paid on common stock held in trust for employees who were granted performance-contingent share awards and who deferred receipt of such awards, and (iii) the surrender to Pfizer of 9,03440,218 shares of common stock to satisfy tax withholding obligations in connection with the vesting of restricted stock and restricted stock units issued to employees.employees and the reduction of first-quarter 2007 reported common stock surrendered to satisfy tax withholding obligations by 217,336 shares and (iv) the receipt of 3,051,090 shares of common stock upon the maturity and settlement of our only forward-purchase contracts with respect to our own stock.

Item 3.  Defaults Upon Senior Securities.

None

Item 4.  Submission of Matters to a Vote of Security Holders

None

Item 5.  Other Information.

None

Item 6.

Exhibits.

  

1)  Exhibit 3.1

-

Restated Certificate of Incorporation dated April 12, 2004

2)  Exhibit 3.2

-

Amendment dated May 1, 2006 to Restated Certificate of Incorporation dated April 12, 2004

3)  Exhibit 12

-

Computation of Ratio of Earnings to Fixed Charges

  

4)2)  Exhibit 15

-

Accountants' Acknowledgment

  

5)3)  Exhibit 31.1

-

Certification by the Chief Executive Officer Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

  

6)4)  Exhibit 31.2

-

Certification by the Chief Financial Officer Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

  

7)5)  Exhibit 32.1

-

Certification by the Chief Executive Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

  

8)6)  Exhibit 32.2

-

Certification by the Chief Financial Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

SIGNATURE

Under the requirements of the Securities Exchange Act of 1934, this report was signed on behalf of the Registrant by the authorized person named below.

  

Pfizer Inc.

(Registrant)

  

  

Dated:  August 11, 20066, 2007

/s/ Loretta V. Cangialosi

  

Loretta V. Cangialosi, Vice President, Controller
(Principal Accounting Officer and
Duly Authorized Officer)

Exhibit 12

PFIZER INC. AND SUBSIDIARY COMPANIES
COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES

Six
Months
Ended
July 2,

Year Ended December 31,

Six Months
Ended
July 1,

Year Ended December 31,

(in millions, except ratios)

2006

  

2005

2004

2003

2002

2001

2007

  

2006

2005

2004

2003

2002

Determination of earnings:

Income from continuing operations before provision for taxes on income, minority interests and cumulative effect of a change in accounting principles

$

7,353

$

10,800

$

13,456

$

2,816

$

11,247

$

9,469

$

5,672

$

13,028

$

10,800

$

13,403

$

2,781

$

11,269

Less:

Minority interests

5

12

7

1

3

12

5

12

12

7

1

3

Income adjusted for minority interest

7,348

10,788

13,449

2,815

11,244

9,457

Income adjusted for minority interests

5,667

13,016

10,788

13,396

2,780

11,266

Add:

Fixed charges

377

630

505

438

318

301

290

642

622

505

438

318

Total earnings as defined

$

7,725

$

11,418

$

13,954

$

3,253

$

11,562

$

9,758

$

5,957

$

13,658

$

11,410

$

13,901

$

3,218

$

11,584

Fixed charges:

Interest expense (a)

$

297

$

471

$

347

$

270

$

251

$

266

$

214

$

488

$

471

$

347

$

270

$

251

Preferred stock dividends (b)

7

14

12

10

--

--

6

14

14

12

10

--

Rents (c)

73

145

146

158

67

35

70

140

137

146

158

67

Fixed charges

377

630

505

438

318

301

290

642

622

505

438

318

Capitalized interest

15

17

12

20

28

56

20

29

17

12

20

28

Total fixed charges

$

392

$

647

$

517

$

458

$

346

$

357

$

310

$

671

$

639

$

517

$

458

$

346

Ratio of earnings to fixed charges

19.7

17.6

27.0

7.1

33.4

27.3

19.2

20.4

17.9

26.9

7.0

33.5

All financial information reflects the following as discontinued operations for all periods presented: the Consumer Healthcare business; for 2006, 2005, 2004 and 2003: certain European generics businesses; and for 2004 and 2003: our in-vitro allergy and autoimmune diagnostics testing, and surgical ophthalmics.

All financial information reflects the following as discontinued operations for 2003 2002, and 2001:2002: our confectionery, shaving and fish-care products businesses, as well as the Estrostep, Loestrin and femhrt women's health product lines for all the years presented.

(a)

Interest expense includes amortization of debt premium, discount and expenses. Interest expense does not include interest related to uncertain tax positions of $135 million for the six months ended July 1, 2007; $200 million for the full-year 2006, $203 million for the full-year 2005, $201 million for the full-year 2004, $180 million for the full-year 2003 and $155 million for the full-year 2002.

  

(b)

Preferred stock dividends are from our Series A convertible perpetual preferred stock held by an Employee Stock Ownership Plan assumed in connection with our acquisition of Pharmacia.Pharmacia in 2003.

  

(c)

Rents included in the computation consist of one-third of rental expense, which we believe to be a conservative estimate of an interest factor in our leases, which are not material.

Exhibit 15

ACCOUNTANTS' ACKNOWLEDGMENT

To the Shareholders and Board of Directors of Pfizer Inc:

We hereby acknowledge our awareness of the incorporation by reference of our report dated August 11, 2006,6, 2007, included within the Quarterly Report on Form 10-Q of Pfizer Inc. for the quarter ended July 2, 2006,1, 2007, in the following Registration Statements:

- Form S-8 dated October 27, 1983 (File No. 2-87473),

- Form S-8 dated March 22, 1990 (File No. 33-34139),

- Form S-8 dated January 24, 1991 (File No. 33-38708),

- Form S-8 dated November 18, 1991 (File No. 33-44053),

- Form S-8 dated May 27, 1993 (File No. 33-49631),

- Form S-8 dated May 19, 1994 (File No. 33-53713),

- Form S-8 dated October 5, 1994 (File No. 33-55771),

- Form S-8 dated December 20, 1994 (File No. 33-56979),

- Form S-8 dated March 29, 1996 (File No. 333-02061),

- Form S-8 dated September 25, 1997 (File No. 333-36371),

- Form S-8 dated April 24, 1998 (File No. 333-50899),

- Form S-8 dated April 22, 1999 (File No. 333-76839),

- Form S-8 dated June 19, 2000 (File No. 333-90975),

- Form S-8 dated June 19, 2000 (File No. 333-39606),

- Form S-8 dated June 19, 2000 (File No. 333-39610),

- Form S-3 dated October 20, 2000 (File No. 333-48382),

- Form S-8 dated April 27, 2001 (File No. 333-59660),

- Form S-8 dated April 27, 2001 (File No. 333-59654),

- Form S-3 dated October 30, 2002 (File No. 333-100853),

- Form S-3 dated December 16, 2002 (File No. 33-56435),

- Form S-8 dated April 16, 2003 (File No. 333-104581),

- Form S-8 dated April 16, 2003 (File No. 333-104582),

- Form S-8 dated November 18, 2003 (File No. 333-110571),

- Form S-8 dated December 18, 2003 (File No. 333-111333),

- Form S-8 dated April 26, 2004 (File No.333-114852), and

- Form S-3 dated March 1, 2005 (File No. 333-123058),

- Form S-8 dated March 1, 2007 (File No. 333-140987),

- Form S-3 dated March 1, 2007 (File No. 333-140989), and

- Form S-3 dated March 30, 2007 (File No. 333-141729).

Pursuant to Rule 436(c) under the Securities Act of 1933, such report is not considered a part of a registration statement prepared or certified by an accountant or a report prepared or certified by an accountant within the meaning of Sections 7 and 11 of that Act.

KPMG LLP

New York, New York
August 11, 20066, 2007

Exhibit 31.1

CERTIFICATION BY THE CHIEF EXECUTIVE OFFICER PURSUANT TO
SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I, Jeffrey B. Kindler, certify that:

1.

I have reviewed this report on Form 10-Q of Pfizer Inc.;

  

2.

Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

  

3.

Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

  

4.

The registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

  

a)

Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

  

b)

Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

  

c)

Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

  

d)

Disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most recent fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

  

5.

The registrant's other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

  

a)

All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

  

b)

Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Date:  August 11, 20066, 2007

  

/s/ Jeffrey B. Kindler

Jeffrey B. Kindler
Chairman of the Board and Chief Executive Officer

Exhibit 31.2

CERTIFICATION BY THE CHIEF FINANCIAL OFFICER PURSUANT TO
SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I, Alan G. Levin, certify that:

1.

I have reviewed this report on Form 10-Q of Pfizer Inc.;

  

2.

Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

  

3.

Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

  

4.

The registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

  

a)

Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

  

b)

Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

  

c)

Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

  

d)

Disclosed in this report any change in the registrant's internal control over financial reporting that occurred during the registrant's most recent fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting; and

  

5.

The registrant's other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

  

a)

All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant's ability to record, process, summarize and report financial information; and

  

b)

Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Date:  August 11, 20066, 2007

  

/s/ Alan G. Levin

Alan G. Levin
Senior Vice President and Chief Financial Officer

Exhibit 32.1

Certification by the Chief Executive Officer Pursuant to 18 U. S. C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

Pursuant to 18 U. S. C. Section 1350, I, Jeffrey B. Kindler, hereby certify that, to the best of my knowledge, the Quarterly Report on Form 10-Q of Pfizer Inc. on Form 10-Q for the quarter ended July 2, 20061, 2007 (the "Report") fully complies with the requirements of Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934, and that the information contained in that Report fairly presents, in all material respects, the financial condition and results of operations of Pfizer Inc.

  

/s/ Jeffrey B. Kindler                                            
Jeffrey B. Kindler
Chairman of the Board and Chief Executive Officer
August 11, 20066, 2007

This certification accompanies this Report on Form 10-Q pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 and shall not, except to the extent required by such Act, be deemed filed by the Company for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"). Such certification will not be deemed to be incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, except to the extent that the Company specifically incorporates it by reference.

Exhibit 32.2

Certification by the Chief Financial Officer Pursuant to 18 U. S. C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

Pursuant to 18 U. S. C. Section 1350, I, Alan G. Levin, hereby certify that, to the best of my knowledge, the Quarterly Report on Form 10-Q of Pfizer Inc. on Form 10-Q for the quarter ended July 2, 20061, 2007 (the "Report") fully complies with the requirements of Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934, and that the information contained in that Report fairly presents, in all material respects, the financial condition and results of operations of Pfizer Inc.

/s/ Alan G. Levin            
Alan G. Levin
Senior Vice President and Chief Financial Officer
August 11, 20066, 2007

This certification accompanies this Report on Form 10-Q pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 and shall not, except to the extent required by such Act, be deemed filed by the Company for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"). Such certification will not be deemed to be incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Exchange Act, except to the extent that the Company specifically incorporates it by reference.