UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 10-Q

ý Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 for the Quarter Ended
April 1, 2017March 31, 2018
¨ Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Commission File Number 1-8002
THERMO FISHER SCIENTIFIC INC.
(Exact name of Registrant as specified in its charter)
Delaware04-2209186
(State of incorporation or organization)(I.R.S. Employer Identification No.)
  
168 Third Avenue 
Waltham, Massachusetts02451
(Address of principal executive offices)(Zip Code)

Registrant’s telephone number, including area code: (781) 622-1000
Indicate by check mark whether the Registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months and (2) has been subject to such filing requirements for the past 90 days. Yes ý  No o
Indicate by check mark whether the Registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the Registrant was required to submit and post such files). Yes ý  No o
Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large"large accelerated filer,” “accelerated" "accelerated filer,” “smaller" "smaller reporting company”company" and "emerging growth company" in Rule 12b-2 of the Exchange Act.
Large accelerated filer ý                                              Accelerated filer o                                       Non-accelerated filer o
Smaller reporting company o                                      Emerging growth company  o
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.  o
Indicate by check mark whether the Registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes o  No ý
Indicate the number of shares outstanding of each of the issuer’s classes of Common Stock, as of the latest practicable date.
 Class Outstanding at April 1, 2017March 31, 2018 
 Common Stock, $1.00 par value 391,219,918402,323,310 



THERMO FISHER SCIENTIFIC INC.
QUARTERLY REPORT ON FORM 10-Q
FOR THE QUARTER ENDED APRIL 1, 2017MARCH 31, 2018
 TABLE OF CONTENTS 
  Page
 PART I 
   
   
   
   
   
 PART II 
   
   
   
   

THERMO FISHER SCIENTIFIC INC.

PART IFINANCIAL INFORMATION
Item 1.Financial Statements
CONSOLIDATED BALANCE SHEET
(Unaudited)
 April 1,
 December 31,
 March 31,
 December 31,
(In millions except share and per share amounts) 2017
 2016
 2018
 2017
        
Assets        
Current Assets:        
Cash and cash equivalents $713.3
 $786.2
 $950
 $1,335
Accounts receivable, less allowances of $87.2 and $77.3 3,096.5
 3,048.5
Accounts receivable, less allowances of $114 and $109 3,990
 3,879
Inventories 2,327.1
 2,213.3
 2,891
 2,971
Refundable income taxes 427.0
 378.3
 540
 432
Other current assets 684.2
 594.7
 1,217
 804
        
Total current assets 7,248.1
 7,021.0
 9,588
 9,421
        
Property, Plant and Equipment, Net 2,563.3
 2,577.8
 4,059
 4,047
Acquisition-related Intangible Assets, Net 13,821.7
 13,969.0
 16,393
 16,684
Other Assets 1,020.2
 1,011.9
 1,178
 1,227
Goodwill 21,560.3
 21,327.8
 25,362
 25,290
        
Total Assets $46,213.6
 $45,907.5
 $56,580
 $56,669
        
Liabilities and Shareholders' Equity        
Current Liabilities:        
Short-term obligations and current maturities of long-term obligations $1,882.4
 $1,255.5
 $2,814
 $2,135
Accounts payable 1,031.0
 926.2
 1,354
 1,428
Accrued payroll and employee benefits 520.8
 708.7
 643
 918
Accrued income taxes 82.2
 165.4
Contract liabilities 909
 
Deferred revenue 538.9
 485.9
 
 719
Other accrued expenses 1,247.6
 1,324.1
 1,352
 1,848
        
Total current liabilities 5,302.9
 4,865.8
 7,072
 7,048
        
Deferred Income Taxes 2,463.4
 2,557.4
 2,606
 2,766
Other Long-term Liabilities 1,463.7
 1,572.6
 2,657
 2,569
Long-term Obligations 15,188.4
 15,372.4
 18,122
 18,873
        
Shareholders' Equity:        
Preferred stock, $100 par value, 50,000 shares authorized; none issued 

 

 

 

Common stock, $1 par value, 1,200,000,000 shares authorized; 416,414,308 and 415,138,564 shares issued 416.4
 415.1
Common stock, $1 par value, 1,200,000,000 shares authorized; 429,442,440 and 428,327,873 shares issued 429
 428
Capital in excess of par value 12,252.0
 12,139.6
 14,319
 14,177
Retained earnings 14,419.4
 13,926.9
 16,542
 15,914
Treasury stock at cost, 25,194,390 and 21,690,679 shares (2,819.1) (2,306.0)
Treasury stock at cost, 27,119,130 and 27,013,311 shares (3,125) (3,103)
Accumulated other comprehensive items (2,473.5) (2,636.3) (2,042) (2,003)
        
Total shareholders' equity 21,795.2
 21,539.3
 26,123
 25,413
        
Total Liabilities and Shareholders' Equity $46,213.6
 $45,907.5
 $56,580
 $56,669

The accompanying notes are an integral part of these consolidated financial statements.

3



THERMO FISHER SCIENTIFIC INC.

CONSOLIDATED STATEMENT OF INCOME
(Unaudited)
 Three Months Ended Three Months Ended
 April 1,
 April 2,
 March 31,
 April 1,
(In millions except per share amounts) 2017
 2016
 2018
 2017
        
Revenues        
Product revenues $4,102.1
 $3,690.4
 $4,528
 $4,102
Service revenues 662.9
 604.4
 1,325
 663
        
Total revenues 4,765.0
 4,294.8
 5,853
 4,765
        
Costs and Operating Expenses:        
Cost of product revenues 2,129.6
 1,933.6
 2,325
 2,129
Cost of service revenues 442.9
 403.3
 948
 443
Selling, general and administrative expenses 1,331.2
 1,212.9
 1,515
 1,334
Research and development expenses 215.4
 176.5
 234
 215
Restructuring and other costs, net 23.5
 50.6
 45
 24
        
Total costs and operating expenses 4,142.6
 3,776.9
 5,067
 4,145
        
Operating Income 622.4
 517.9
 786
 620
Other Expense, Net (119.5) (94.9) (152) (117)
        
Income from Continuing Operations Before Income Taxes 502.9
 423.0
Benefit from (Provision for) Income Taxes 48.5
 (20.7)
    
Income from Continuing Operations 551.4
 402.3
Loss from Discontinued Operations (net of income tax benefit of $0.1) 
 (0.1)
Income Before Income Taxes 634
 503
(Provision for) Benefit from Income Taxes (55) 48
        
Net Income $551.4
 $402.2
 $579
 $551
    
Earnings per Share from Continuing Operations    
Basic $1.41
 $1.02
Diluted $1.40
 $1.01
        
Earnings per Share        
Basic $1.41
 $1.02
 $1.44
 $1.41
Diluted $1.40
 $1.01
 $1.43
 $1.40
        
Weighted Average Shares        
Basic 391.0
 395.8
 402
 391
Diluted 394.1
 398.7
 406
 394
        
Cash Dividends Declared per Common Share $0.15
 $0.15
 $0.17
 $0.15

The accompanying notes are an integral part of these consolidated financial statements.


THERMO FISHER SCIENTIFIC INC.

 CONSOLIDATED STATEMENT OF COMPREHENSIVE INCOME
(Unaudited)
 Three Months Ended Three Months Ended
 April 1,
 April 2,
 March 31,
 April 1,
(In millions) 2017
 2016
 2018
 2017
        
Comprehensive Income        
Net Income $551.4
 $402.2
 $579
 $551
        
Other Comprehensive Items:        
Currency translation adjustment 160.0
 169.9
Currency translation adjustment (net of tax benefit of $47 and $0) 47
 160
Unrealized gains and losses on available-for-sale investments:        
Unrealized holding gains (losses) arising during the period (net of tax provision (benefit) of $0.3 and ($0.4)) 1.1
 (1.5)
Unrealized holding gains arising during the period (net of tax provision of $0 and $0) 
 1
Unrealized gains and losses on hedging instruments:        
Unrealized losses on hedging instruments (net of tax benefit of $22.4) 
 (36.6)
Reclassification adjustment for losses included in net income (net of tax benefit of $1.1 and $0.5) 1.8
 0.8
Reclassification adjustment for losses included in net income (net of tax benefit of $1 and $1) 2
 2
Pension and other postretirement benefit liability adjustments:        
Pension and other postretirement benefit liability adjustments arising during the period (net of tax benefit of $0.7 and $1.1) (2.0) (3.4)
Amortization of net loss and prior service benefit included in net periodic pension cost (net of tax benefit of $0.7 and $0.3) 1.9
 1.4
Pension and other postretirement benefit liability adjustments arising during the period (net of tax provision (benefit) of ($1) and ($1)) (2) (2)
Amortization of net loss and prior service benefit included in net periodic pension cost (net of tax benefit of $1 and $1) 2
 2
        
Total other comprehensive items 162.8
 130.6
 49
 163
        
Comprehensive Income $714.2
 $532.8
 $628
 $714

The accompanying notes are an integral part of these consolidated financial statements.


THERMO FISHER SCIENTIFIC INC.

CONSOLIDATED STATEMENT OF CASH FLOWS
(Unaudited)
 Three Months Ended Three Months Ended
 April 1,
 April 2,
 March 31,
 April 1,
(In millions) 2017
 2016
 2018
 2017
        
Operating Activities        
Net income $551.4
 $402.2
 $579
 $551
Loss from discontinued operations 
 0.1
        
Income from continuing operations 551.4
 402.3
    
Adjustments to reconcile income from continuing operations to net cash provided by operating activities:    
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation and amortization 464.5
 416.1
 575
 465
Change in deferred income taxes (127.3) (88.8) (121) (127)
Non-cash stock-based compensation 33.0
 33.4
 43
 33
Non-cash charges for sale of inventories revalued at the date of acquisition 30.7
 6.2
 3
 31
Other non-cash expenses, net 28.3
 14.2
 24
 28
Changes in assets and liabilities, excluding the effects of acquisitions and dispositions:        
Accounts receivable (18.0) (29.9) (71) (18)
Inventories (105.1) (56.2) (124) (105)
Other assets (133.8) (38.7) (192) (134)
Accounts payable 114.0
 34.8
 (94) 114
Other liabilities (302.8) (335.0) (520) (303)
Contributions to retirement plans (172.5) (22.2) (24) (173)
        
Net cash provided by continuing operations 362.4
 336.2
 78
 362
Net cash used in discontinued operations (0.9) (1.5) 
 (1)
        
Net cash provided by operating activities 361.5
 334.7
 78
 361
        
Investing Activities  
  
  
  
Acquisitions, net of cash acquired (300.7) (1,032.4) (57) (301)
Purchase of property, plant and equipment (93.4) (115.1) (118) (93)
Proceeds from sale of property, plant and equipment 1.1
 6.0
 2
 1
Proceeds from sale of investments 11.7
 3.9
Other investing activities, net (0.6) (1.3) (6) 11
        
Net cash used in investing activities $(381.9) $(1,138.9) $(179) $(382)


THERMO FISHER SCIENTIFIC INC.

CONSOLIDATED STATEMENT OF CASH FLOWS (Continued)
(Unaudited)
 Three Months Ended Three Months Ended
 April 1,
 April 2,
 March 31,
 April 1,
(In millions) 2017
 2016
 2018
 2017
        
Financing Activities        
Net proceeds from issuance of debt $519.0
 $998.8
 $
 $519
Repayment of debt (703.2) (1.3) (453) (703)
Net proceeds from issuance of commercial paper 2,361.1
 2,359.7
Proceeds from issuance of commercial paper 1,306
 2,361
Repayments of commercial paper (1,795.3) (1,185.8) (1,124) (1,795)
Purchases of company common stock (500.0) (1,000.0) 
 (500)
Dividends paid (59.1) (60.3) (60) (59)
Net proceeds from issuance of company common stock under employee stock plans 58.2
 31.7
 39
 58
Other financing activities, net 
 (0.4)
Other financing activities (50) 
        
Net cash (used in) provided by financing activities (119.3) 1,142.4
Net cash used in financing activities (342) (119)
        
Exchange Rate Effect on Cash 65.8
 37.0
 57
 66
        
(Decrease) Increase in Cash, Cash Equivalents and Restricted Cash (73.9) 375.2
Decrease in Cash, Cash Equivalents and Restricted Cash (386) (74)
Cash, Cash Equivalents and Restricted Cash at Beginning of Period 810.8
 466.3
 1,361
 811
        
Cash, Cash Equivalents and Restricted Cash at End of Period $736.9
 $841.5
 $975
 $737
        
See Note 12 for supplemental cash flow information.

The accompanying notes are an integral part of these consolidated financial statements.


THERMO FISHER SCIENTIFIC INC.

CONSOLIDATED STATEMENT OF SHAREHOLDERS' EQUITY
(Unaudited)
 Common Stock Capital in Excess of Par Value
 Retained Earnings
 Treasury Stock Accumulated Other Comprehensive Items
 Total Shareholders' Equity
 Common Stock Capital in Excess of Par Value
 Retained Earnings
 Treasury Stock Accumulated Other Comprehensive Items
 Total Shareholders' Equity
(In millions) Shares
 Amount
 Shares
 Amount
  Shares
 Amount
 Shares
 Amount
 
                
Balance at December 31, 2015 411.9
 $411.9
 $11,801.2
 $12,142.3
 12.3
 $(1,007.9) $(1,997.3) $21,350.2
                
Issuance of shares under employees' and directors' stock plans 1.4
 1.4
 57.4
 
 0.1
 (18.3) 
 40.5
Stock-based compensation 
 
 33.4
 
 
 
 
 33.4
Tax benefit related to employees' and directors' stock plans 
 
 26.8
 
 
 
 
 26.8
Purchases of company common stock 
 
 
 
 7.3
 (1,000.0) 
 (1,000.0)
Dividends declared 
 
 
 (59.3) 
 
 
 (59.3)
Net income 
 
 
 402.2
 
 
 
 402.2
Other comprehensive items 
 
 
 
 
 
 130.6
 130.6
                
Balance at April 2, 2016 413.3
 $413.3
 $11,918.8
 $12,485.2
 19.7
 $(2,026.2) $(1,866.7) $20,924.4
                                
Balance at December 31, 2016 415.1
 $415.1
 $12,139.6
 $13,926.9
 21.7
 $(2,306.0) $(2,636.3) $21,539.3
 415
 $415
 $12,140
 $13,927
 22
 $(2,306) $(2,636) $21,540
Issuance of shares under employees' and directors' stock plans 1.3
 1.3
 79.4
 
 0.1
 (13.1) 
 67.6
 1
 1
 79
 
 
 (13) 
 67
Stock-based compensation 
 
 33.0
 
 
 
 
 33.0
 
 
 33
 
 
 
 
 33
Purchases of company common stock 
 
 
 
 3.4
 (500.0) 
 (500.0) 
 
 
 
 3
 (500) 
 (500)
Dividends declared 
 
 
 (58.9) 
 
 
 (58.9) 
 
 
 (59) 
 
 
 (59)
Net income 
 
 
 551.4
 
 
 
 551.4
 
 
 
 551
 
 
 
 551
Other comprehensive items 
 
 
 
 
 
 162.8
 162.8
 
 
 
 
 
 
 163
 163
                                
Balance at April 1, 2017 416.4
 $416.4
 $12,252.0
 $14,419.4
 25.2
 $(2,819.1) $(2,473.5) $21,795.2
 416
 $416
 $12,252
 $14,419
 25
 $(2,819) $(2,473) $21,795
                
Balance at December 31, 2017 428
 $428
 $14,177
 $15,914
 27
 $(3,103) $(2,003) $25,413
Cumulative effect of accounting changes 
 
 
 118
 
 
 (88) 30
Issuance of shares under employees' and directors' stock plans 1
 1
 72
 
 
 (22) 
 51
Stock-based compensation 
 
 43
 
 
 
 
 43
Dividends declared 
 
 
 (69) 
 
 
 (69)
Net income 
 
 
 579
 
 
 
 579
Other comprehensive items 
 
 
 
 
 
 49
 49
Other 
 
 27
 
 
 
 
 27
                
Balance at March 31, 2018 429
 $429
 $14,319
 $16,542
 27
 $(3,125) $(2,042) $26,123

The accompanying notes are an integral part of these consolidated financial statements.

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Unaudited)


Note 1.
Nature of Operations and Summary of Significant Accounting Policies
Nature of Operations
Thermo Fisher Scientific Inc. (the company or Thermo Fisher) enables customers to make the world healthier, cleaner and safer by providing analytical instruments, equipment, reagents and consumables, software and services for research, manufacturing, analysis, discovery and diagnostics. Markets served include pharmaceutical and biotech, academic and government, industrial and applied, as well as healthcare and diagnostics.
Interim Financial Statements
The interim consolidated financial statements presented herein have been prepared by the company, are unaudited and, in the opinion of management, reflect all adjustments of a normal recurring nature necessary for a fair statement of the financial position at April 1, 2017,March 31, 2018, the results of operations for the three-month periods ended March 31, 2018 and April 1, 2017, and April 2, 2016, and the cash flows for the three-month periods ended March 31, 2018 and April 1, 2017 and April 2, 2016.2017. Interim results are not necessarily indicative of results for a full year.
The consolidated balance sheet presented as of December 31, 2016,2017, has been derived from the audited consolidated financial statements as of that date. The consolidated financial statements and notes are presented as permitted by Form 10-Q and do not contain all information that is included in the annual financial statements and notes thereto of the company. The consolidated financial statements and notes included in this report should be read in conjunction with the 20162017 financial statements and notes included in the company’s Annual Report on Form 10-K filed with the Securities and Exchange Commission (SEC).
Note 1 to the consolidated financial statements for 20162017 describes the significant accounting estimates and policies used in preparation of the consolidated financial statements. ThereExcept for the accounting for revenue arising from contracts with customers as noted below there have been no material changes in the company’s significant accounting policies during the three months ended April 1, 2017.March 31, 2018.
InventoriesRevenue Recognition
The componentscompany recognizes revenue for the transfer of inventoriespromised goods or services to customers in an amount that reflects the consideration to which the company expects to be entitled in exchange for those goods or services.
Consumables revenues consist of single-use products and are recognized at a point in time following the transfer of control of such products to the customer, which generally occurs upon shipment. Instruments revenues typically consist of longer-lived assets that, for the substantial majority of sales, are recognized at a point in time in a manner similar to consumables. Service revenues (clinical trial logistics, pharmaceutical development and manufacturing services, asset management, diagnostic testing, training, service contracts, and field services including related time and materials) are recognized over time as follows:
  April 1,
 December 31,
(In millions) 2017
 2016
     
Raw Materials $521.6
 $466.3
Work in Process 361.5
 327.9
Finished Goods 1,444.0
 1,419.1
     
Inventories $2,327.1
 $2,213.3
Property, Plantcustomers receive and Equipment
Property, plantconsume the benefits of such services. For revenues recognized over time, the company generally uses costs accumulated as inputs to measure progress. For contracts that contain multiple performance obligations, the company allocates the consideration to which it expects to be entitled to each performance obligation based on relative standalone selling prices and equipment consistsrecognizes the related revenue when or as control of each individual performance obligation is transferred to customers. The company exercises judgment in determining the timing of revenue by analyzing the point in time or the period over which the customer has the ability to direct the use of and obtain substantially all of the following:remaining benefits of the asset. The company expenses contract costs that would otherwise be capitalized and amortized over a period of less than one year.
Payments from customers for most instruments, consumables and services are typically due in a fixed number of days after shipment or delivery of the product. Service arrangements commonly call for payments in advance of performing the work (e.g. extended service contracts), upon completion of the service (e.g. pharmaceutical development and manufacturing) or a mix of both.
  April 1,
 December 31,
(In millions) 2017
 2016
     
Land $306.3
 $305.6
Buildings and Improvements 1,172.6
 1,154.2
Machinery, Equipment and Leasehold Improvements 3,033.8
 2,955.7
     
Property, Plant and Equipment, at Cost 4,512.7
 4,415.5
Less: Accumulated Depreciation and Amortization 1,949.4
 1,837.7
     
Property, Plant and Equipment, Net $2,563.3
 $2,577.8
See Note 3 for revenue disaggregated by type and by geographic region as well as further information about remaining performance obligations.
Contract-related Balances
Contract assets include revenues recognized in advance of billings and are recorded net of estimated losses resulting from the inability to invoice customers. Contract assets are classified as current or noncurrent based on the amount of time expected

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Acquisition-related Intangible Assets
Acquisition-related intangibleto lapse until the company's right to consideration becomes unconditional. Current contract assets and noncurrent contract assets are included within other current assets and other assets, respectively, in the accompanying balance sheet.
Contract liabilities include billings in excess of revenues recognized, such as those resulting from customer advances and deposits and unearned revenue on service contracts. Contract liabilities are classified as current or noncurrent based on the periods over which remaining performance obligations are expected to be transferred to customers. Noncurrent contract liabilities are included within other long-term liabilities in the accompanying balance sheet.
Contract asset and liability balances are as follows:
  Balance at April 1, 2017 Balance at December 31, 2016
(In millions) Gross
 Accumulated Amortization
 Net
 Gross
 Accumulated Amortization
 Net
             
Definite Lived:            
Customer relationships $13,318.0
 $(5,046.4) $8,271.6
 $13,167.3
 $(4,821.4) $8,345.9
Product technology 5,818.8
 (2,350.6) 3,468.2
 5,679.7
 (2,204.2) 3,475.5
Tradenames 1,473.7
 (681.4) 792.3
 1,452.2
 (646.0) 806.2
Other 33.3
 (33.3) 
 33.0
 (33.0) 
             
  20,643.8
 (8,111.7) 12,532.1
 20,332.2
 (7,704.6) 12,627.6
Indefinite Lived:            
Tradenames 1,234.8
 
 1,234.8
 1,234.8
 
 1,234.8
In-process research and development 54.8
 
 54.8
 106.6
 
 106.6
             
  1,289.6
 
 1,289.6
 1,341.4
 
 1,341.4
             
Acquisition-related Intangible Assets $21,933.4
 $(8,111.7) $13,821.7
 $21,673.6
 $(7,704.6) $13,969.0
  March 31,
 January 1,
(In millions) 2018
 2018
     
Current Contract Assets, Net
 $458
 $396
Current Contract Liabilities
 909
 805
Noncurrent Contract Liabilities
 317
 302
Noncurrent contract assets were immaterial in 2018. In the first three months of 2018, the company recognized revenue of $308 million that was included in the contract liabilities balance at January 1, 2018.
Warranty Obligations
The liability for warranties is included in other accrued expenses in the accompanying balance sheet. The changes in the carrying amount of standard product warranty obligations are as follows:
 Three Months Ended Three Months Ended
 April 1,
 April 2,
 March 31,
 April 1,
(In millions) 2017
 2016
 2018
 2017
        
Beginning Balance $77.9
 $55.8
 $87
 $78
Provision charged to income 25.3
 21.9
 31
 25
Usage (24.6) (20.3) (28) (25)
Acquisitions 0.5
 1.1
 
 1
Adjustments to previously provided warranties, net (0.6) (0.6) (1) (1)
Currency translation 0.8
 1.0
 1
 1
        
Ending Balance $79.3
 $58.9
 $90
 $79
Inventories
The components of inventories are as follows:
  March 31,
 December 31,
(In millions) 2018
 2017
     
Raw Materials $776
 $708
Work in Process 402
 505
Finished Goods 1,713
 1,758
     
Inventories $2,891
 $2,971

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Property, Plant and Equipment
Property, plant and equipment consists of the following:
  March 31,
 December 31,
(In millions) 2018
 2017
     
Land $405
 $401
Buildings and Improvements 1,688
 1,662
Machinery, Equipment and Leasehold Improvements 4,427
 4,276
     
Property, Plant and Equipment, at Cost 6,520
 6,339
Less: Accumulated Depreciation and Amortization 2,461
 2,292
     
Property, Plant and Equipment, Net $4,059
 $4,047
Acquisition-related Intangible Assets
Acquisition-related intangible assets are as follows:
  Balance at March 31, 2018 Balance at December 31, 2017
(In millions) Gross
 Accumulated Amortization
 Net
 Gross
 Accumulated Amortization
 Net
             
Definite Lived:            
Customer relationships $17,439
 $(6,170) $11,269
 $17,356
 $(5,902) $11,454
Product technology 6,107
 (2,953) 3,154
 6,046
 (2,811) 3,235
Tradenames 1,547
 (862) 685
 1,538
 (817) 721
Other 35
 (35) 
 34
 (34) 
             
  25,128
 (10,020) 15,108
 24,974
 (9,564) 15,410
Indefinite Lived:            
Tradenames 1,235
 N/A
 1,235
 1,235
 N/A
 1,235
In-process research and development 50
 N/A
 50
 39
 N/A
 39
             
  1,285
 N/A
 1,285
 1,274
 N/A
 1,274
             
Acquisition-related Intangible Assets $26,413
 $(10,020) $16,393
 $26,248
 $(9,564) $16,684
Use of Estimates
The preparation of financial statements in conformity with generally accepted accounting principles requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. In addition, significant estimates were made in estimating future cash flows to assess potential impairment of assets and in determining the fair value of acquired intangible assets (Note 2) and the ultimate loss from abandoning leases at facilities being exited (Note 13). Actual results could differ from those estimates.
Recent Accounting Pronouncements
In February 2018, the FASB issued new guidance to allow reclassifications from accumulated other comprehensive items (AOCI) to retained earnings for certain tax effects on items within AOCI resulting from the Tax Cuts and Jobs Act of 2017 (the Tax Act). The company adopted this guidance in January 2018 and recorded the reclassifications in the period of adoption. The balance sheet impact of adopting this guidance is included in the table below. This guidance only relates to the effects of the

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Tax Act. For all other tax law changes that have occurred or may occur in the future, the company reclassifies the tax effects to the consolidated statement of income on an item-by-item basis when the pre-tax item in AOCI is reclassified to income.
In December 2017, the SEC staff issued guidance to address the application of accounting guidance in situations when a registrant does not have the necessary information available, prepared, or analyzed (including computations) in reasonable detail to complete the accounting for certain income tax effects of the Tax Act enacted on December 22, 2017. The company reported provisional amounts in its 2017 financial statements for certain income tax effects of the Tax Act for which a reasonable estimate could be determined but for which the accounting impact may change. For example, these estimates may be impacted by the need for further analysis and future clarification and guidance regarding available tax accounting methods and elections, earnings and profits computations and state tax conformity to federal changes. Adjustments to provisional amounts identified during the measurement period, which may be up to December 22, 2018, will be included as adjustments to Benefit from (Provision for) Income Taxes in the period the amounts are determined.
In August 2017, the FASB issued new guidance to simplify the application of hedge accounting guidance. Among other things, the new guidance will permit more hedging strategies to qualify for hedge accounting, allow for additional time to perform an initial assessment of a hedge’s effectiveness, and permit a qualitative effectiveness test for certain hedges after initial qualification. The company adopted this guidance in January 2018. The balance sheet impact of adopting this guidance is included in the table below.
In March 2017, the FASB issued new guidance intended to improve the presentation of net periodic pension cost and net periodic postretirement benefit cost. The new guidance requires the service cost component of net periodic cost be reported in the same line item(s) as other employee compensation costs and all other components of the net periodic cost be reported in the

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

income statement below operating income. The company adopted this guidance is effective foron January 1, 2018 and applied the company in 2018. Thechanges to the statement of income retrospectively. As a result of adoption of this guidance, is not expected to have a material impact on the company’s consolidated financial statements.accompanying 2017 statement of income reflects the following changes from previously reported amounts:
In January 2017, the FASB issued new guidance that eliminates the requirement to calculate the implied fair value of goodwill to measure a goodwill impairment charge. Instead, the new guidance will require entities to record an impairment charge based on the excess of a reporting unit’s carrying amount over its fair value. The guidance is effective for the company in 2020. Early adoption is permitted. The adoption of this guidance is not expected to have a material impact on the company’s consolidated financial statements.
  Three Months Ended
  April 1,
(In millions) 2017
   
Increase in Total Costs and Operating Expenses (principally Selling, General and Administrative Expenses) $2
Decrease in Operating Income 2
Increase in Other Income (Expense) 2
In January 2017, the FASB issued new guidance clarifying the definition of a business and providing criteria to determine when an integrated set of assets and activities is not defined as a business. The new guidance requires such integrated sets to be defined as an asset (and not a business) if substantially all of the fair value of the gross assets acquired or disposed is concentrated in a single identifiable asset or a group of similar identifiable assets. The guidance is effective for the company in 2018. Early adoption is permitted. The adoption of this guidance isas of January 1, 2018 did not expected to have a material impact on the company’s consolidated financial statements.
In November 2016, the FASB issued new guidance intended to reduce diversity in practice in the classification and presentation of changes in restricted cash on the statement of cash flows. The company adopted this guidance on January 1, 2017 and applied the changes to the statement of cash flows retrospectively, as required. The table below summarizes the impact of adopting this and related guidance on the company’s consolidated statement of cash flows for the three months ended April 2, 2016.
In October 2016, the FASB issued new guidance eliminating the deferral of the tax effects of intra-entity asset transfers. The guidance is effective for the company in 2018. The impact of this guidance in future periods will be dependent on the extent of future asset transfers which usually occur in connection with planning around acquisitions and other business structuring activities.
In August 2016, the FASB issued new guidance intended to reduce diversity in practice in how certain transactions are classified on the statement of cash flows. The company adopted this guidance on January 1, 2017 and applied the changes to the statement of cash flows retrospectively, as required. The table below summarizes thebalance sheet impact of adopting this and related guidance on the company’s consolidated statementas of cash flows for the three months ended April 2, 2016.
In March 2016, the FASB issued new guidance which affects the accounting for stock-based compensation. The new guidance simplifies the accounting for share-based payment transactions, including the income tax consequences, classification of awards as either equity or liabilities, and classification on the statement of cash flows. The company adopted this guidance on January 1, 2017 and applied the changes to the statement of cash flows retrospectively. The table below summarizes the impact of adopting this and related guidance on the company’s consolidated statement of cash flows. Adoption of this guidance decreased the company's tax provision2018 is included in the first three months of 2017 by $24 million and increased diluted earnings per share for the same period by $0.06. The impact in future periods will be dependent upon changes in the company's stock price, the volume of employee stock option exercises and the timing of service- and performance-based restricted unit vesting.table below.
The guidance issued in November 2016, August 2016 and the provisions of the guidance issued in March 2016 which affected classification on the statement of cash flows were applied retrospectively. As a result of adoption of this guidance, the accompanying statement of cash flows for the first three months of 2016 reflect the following changes from previously reported amounts:
  Three Months Ended
(In millions) April 2, 2016
   
Increase in Net Cash Provided by Operating Activities $45.6
Increase in Net Cash Used in Investing Activities (0.4)
Decrease in Net Cash Provided by Financing Activities (45.6)
In February 2016, the FASB issued new guidance which requires lessees to record most leases on their balance sheets as lease liabilities, initially measured at the present value of the future lease payments, with corresponding right-of-use assets. The new guidance also sets forth new disclosure requirements related to leases. The guidance is effective forcompany plans to adopt the companyguidance in 2019 and must be adopted using a modified retrospective method. Early adoption is permitted. The company is currently evaluating

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

the impact this guidance will have on its consolidated financial statements, however, assets and liabilities will increase upon adoption for right-of-use assets and lease liabilities. The company’s future commitments under lease obligations are summarized in Note 10 to the consolidated financial statements for 20162017 included in the company’scompany's Annual Report on Form 10-K, filed with the SEC.
In January 2016, the FASB issued new guidance which affects the accounting for equity investments, financial liabilities under the fair value option, and the presentation and disclosure requirements for financial instruments. This guidance retains the current accounting for classifying and measuring investments in debt securities and loans, but requires equity investments to be measured at fair value with subsequent changes recognized in net income, except for those accounted

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

for under the equity method or requiring consolidation. The guidance also changes the accounting for investments without a readily determinable fair value and that do not qualify for the practical expedient permitted by the guidance to estimate fair value. A policy election can be made for these investments whereby estimated fair value may be measured at cost and adjusted in subsequent periods for any impairment or changes in observable pricesThe balance sheet impact of identical or similar investments. The guidance is effective for the company in 2018. Early adoption is permitted. The adoption ofadopting this guidance as of January 1, 2018 is not expected to have a material impact on the company’s consolidated financial statements.
In July 2015, the FASB issued new guidance which requires an entity to measure inventory at the lower of cost and net realizable value. Net realizable value is defined as the estimated selling pricesincluded in the ordinary course of business, less reasonably predictable costs of completion, disposal, and transportation. This guidance does not apply to inventory that is measured using last-in, first-out (LIFO). The guidance was effective for the company in 2017. Adoption of this guidance did not have a material impact on the company’s consolidated financial statements.table below.
In May 2014, the FASB issued new revenue recognition guidance which provides a single comprehensive model for entities to use in accounting for revenue arising from contracts with customers and will supersedesupersedes most currentprevious revenue recognition guidance. The new standard also requires significantly expanded disclosures regarding the qualitative and quantitative information of an entity's nature, amount, timing, and uncertainty of revenue and cash flows arising from contracts with customers. During 2016 and 2017, the FASB issued additional guidance and clarification.clarification, including the elimination of certain SEC Staff Guidance. The guidance is currently effective for the company in 2018. Early adoption is permitted. The company expectshas elected to adopt this guidance on January 1, 2018 through application of the modified retrospective method. The company’s preliminary assessmentmethod by applying it to contracts that were not completed as of its most commonly used customer terms and conditions and routine sales transactions did not identifyDecember 31, 2017 (in addition to new contracts in 2018).
Adoption of new guidance that became effective on January 1, 2018, impacted the company's Consolidated Balance Sheet as follows:
(In millions) December 31,
2017
as Reported

 Impact of Adopting New Revenue Guidance
 Impact of Adopting New Equity Investment Guidance
 Impact of Adopting New Intra-entity Tax Guidance
 Impact of Adopting New Hedge Accounting Guidance
 Impact of Adopting New Tax Effects on Items in AOCI Guidance
 January 1, 2018
as Adopted

               
Accounts Receivable, Less Allowances $3,879
 $(8) $
 $
 $
 $
 $3,871
Inventories 2,971
 (252) 
 
 
 
 2,719
Other Current Assets 804
 296
 
 
 
 
 1,100
Other Assets 1,227
 
 
 (77) 
 
 1,150
Contract Liabilities 
 805
 
 
 
 
 805
Deferred Revenue 719
 (719) 
 
 
 
 
Other Accrued Expenses 1,848
 (153) 
 
 
 
 1,695
Deferred Income Taxes 2,766
 
 
 (57) 
 2
 2,711
Other Long-term Liabilities 2,569
 54
 
 
 
 
 2,623
Long-term Obligations 18,873
 
 
 
 (3) 
 18,870
Retained Earnings 15,914
 49
 (1) (20) 3
 87
 16,032
Accumulated Other Comprehensive Items (2,003) 
 1
 
 
 (89) (2,091)
Had the company continued to use the revenue recognition guidance in effect prior to 2018, no material impacts to its consolidated financial statements from the application of the guidance; however, a broad assessment is ongoing that includes surveying the company’s major businesses concerning any unique customer contract terms or transactions that couldchanges would have implicationsresulted to the timingconsolidated statements of revenue recognitionincome, comprehensive income, or cash flows for the three months ended March 31, 2018, from amounts reported therein. However, inventories would have been $280 million higher and other current assets would have been $344 million lower as of March 31, 2018, primarily as a result of differences in the accounting for pharmaceutical development and manufacturing services under the new revenue guidance. The company expects this undertaking will be completeUnder the prior guidance, costs of these services were recorded in inventory while under the second half of 2017.new guidance, costs are expensed as the manufacturing service is performed and the company's rights to consideration are recorded as contract assets and included in other current assets.


THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Note 2.Acquisitions
The company’s acquisitions have historically been made at prices above the determined fair value of the acquired identifiable net assets, resulting in goodwill, due to expectations of the synergies that will be realized by combining the businesses. These synergies include the elimination of redundant facilities, functions and staffing; use of the company’s existing commercial infrastructure to expand sales of the acquired businesses’ products; and use of the commercial infrastructure of the acquired businesses to cost-effectively expand sales of company products.
Acquisitions have been accounted for using the purchase method of accounting, and the acquired companies’ results have been included in the accompanying financial statements from their respective dates of acquisition. Acquisition transaction costs are recorded in selling, general and administrative expenses as incurred.
20172018
On March 2, 2017, the company acquired, within the Analytical Instruments segment, Core Informatics, a North America-based provider of cloud-based platforms supporting scientific data management, for a total purchase price of $94 million, net of cash acquired. The acquisition enhanced the company's existing informatics solutions. Revenues of Core Informatics were approximately $10 million in 2016. The purchase price exceeded the fair market value of the identifiable net assets and, accordingly, $63 million was allocated to goodwill, $50 million of which is tax deductible.
On February 14, 2017,In 2018, the company acquired, within the Life Sciences Solutions segment, Finesse Solutions,IntegenX Inc., a North America-based developerprovider of scalable control automation systemsa rapid DNA platform for use in forensics and softwarelaw enforcement applications, for bioproduction, for a totalan aggregate purchase price of $220 million, net of cash acquired. The acquisition expanded the company's bioproduction offerings. Revenues of Finesse$65 million.

Note 3.
Revenue
Disaggregated Revenue
Revenue by type is as follows:
  Three Months Ended
  March 31,
(In millions) 2018
   
Revenues  
Consumables $3,111
Instruments 1,416
Services 1,325
   
Consolidated revenues $5,853
Revenue by geographic region is as follows:
  Three Months Ended
  March 31,
(In millions) 2018
   
Revenues  
North America $2,903
Europe 1,518
Asia-Pacific 1,264
Other regions 168
   
Consolidated revenues $5,853
Each reportable segment earns revenues from consumables, instruments and services in North America, Europe, Asia-Pacific and other regions. See note 4 for revenue by reportable segment and other geographic data.

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Solutions were approximately $50 million in 2016. Remaining Performance Obligations
The purchase price exceeded the fair market valueaggregate amount of the identifiable net assets and, accordingly, $127 million wastransaction price allocated to goodwill, nonethe remaining performance obligations for all open customer contracts as of March 31, 2018 was $4.94 billion. The company will recognize revenue for these performance obligations as they are satisfied, the majority of which is tax deductible.
The components ofexpected to occur within the purchase price and net assets acquired for 2017 acquisitions are as follows:
(In millions) Core Informatics
 Finesse Solutions
 Total
       
Purchase Price      
Cash paid $89.2
 $222.6
 $311.8
Debt assumed 
 
 
Purchase price payable 14.6
 
 14.6
Cash acquired (10.1) (2.2) (12.3)
       
  $93.7
 $220.4
 $314.1
       
Net Assets Acquired      
Current assets $2.0
 $21.6
 $23.6
Property, plant and equipment 0.2
 1.6
 1.8
Definite-lived intangible assets:      
Customer relationships 6.3
 67.7
 74.0
Product technology 29.1
 32.0
 61.1
Tradenames and other 2.7
 9.0
 11.7
Indefinite-lived intangible assets:      
In-process research and development 
 1.6
 1.6
Goodwill 62.6
 127.4
 190.0
Other assets 0.1
 0.3
 0.4
Liabilities assumed (9.3) (40.8) (50.1)
       
  $93.7
 $220.4
 $314.1
The weighted-average amortization periods for definite-lived intangible assets acquired in 2017 are 12 years for customer relationships, 10 years for product technology and 8 years for tradenames and other. The weighted average amortization period for all definite-lived intangible assets acquired in 2017 is 11 years.
The preliminary allocation of the purchase price for the 2017 acquisitions was based on estimates of the fair value of the net assets acquired and is subject to adjustment upon finalization of the valuation of the acquired intangible assets in the second quarter of 2017.
Unaudited Pro Forma Information
Had the 2016 acquisitions of FEI Company and Affymetrix, Inc. been completed as of the beginning of 2015, the company’s pro forma results for 2016 would have been as follows:
(In millions except per share amounts) Three Months Ended 
 April 2, 2016

   
Revenues $4,605.0
   
Net Income $376.8
   
Earnings per Share:  
Basic $0.95
Diluted $0.95

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

These pro forma results of operations have been prepared for comparative purposes only, and they do not purport to be indicative of the results of operations that actually would have resulted had the acquisitions occurred on the date indicated or that may result in the future.
The company’s results would not have been materially different from its pro forma results had the company’s other 2016 or 2017 acquisitions occurred at the beginning of 2015 or 2016, respectively.
Revenues of the FEI and Affymetrix acquisitions in the first three months of 2017 were $265 million and $78 million, respectively. Operating loss of the FEI acquisition totaled $17 million in the first three months of 2017 primarily due to acquisition-related and restructuring costs related to synergy planning. The Affymetrix acquisition has been integrated with other parts of the Life Sciences Solutions business and it is not practical to determine its separate operating results beginning in 2017.next twelve months.

Note 3.4.
Business Segment and Geographical Information
The company’s financial performance is reported in four segments. A description of each segment follows.
Life Sciences Solutions: provides an extensive portfolio of reagents, instruments and consumables used in biological and medical research, discovery and production of new drugs and vaccines as well as diagnosis of disease. These products and services are used by customers in pharmaceutical, biotechnology, agricultural, clinical, academic, and government markets.
Analytical Instruments: provides a broad offering of instruments, consumables, software and services that are used for a range of applications in the laboratory, on the production line and in the field. These products and services are used by customers in pharmaceutical, biotechnology, academic, government, environmental and other research and industrial markets, as well as the clinical laboratory.
Specialty Diagnostics: provides a wide range of diagnostic test kits, reagents, culture media, instruments and associated products used to increase the speed and accuracy of diagnoses. These products are used by customers in healthcare, clinical, pharmaceutical, industrial and food safety laboratories.
Laboratory Products and Services: provides virtually everything needed for the laboratory, including a combination of self-manufactured and sourced products for customers in research, academic, government, industrial and an extensive service offering. These products andhealthcare settings. The segment also includes a comprehensive offering of outsourced services are used by customers inthe pharmaceutical biotechnology, academic, government and other researchbiotech industries for drug development, clinical trials logistics and industrial markets, as well as the clinical laboratory.
In January 2017, in connection with a change in management responsibility for certain product lines, the company transferred its plastics for cell culture and vaccines/biologics; sample preparation and analysis; and production chemicals product lines to the Life Sciences Solutions segment from the Laboratory Products and Services segment and transferred its biochemical product line from the Life Sciences Solutions segment to the Laboratory Products and Services segment. These moves are consistent with the company’s historical practice of moving a product line between segments when a shift in strategic focus of either the product line or a segment more closely aligns the product line with a segment different than that in which it had previously been reported. Prior period segment information has been reclassified to reflect these transfers.commercial drug manufacturing.
The company’s management evaluates segment operating performance based on operating income before certain charges/credits to cost of revenues and selling, general and administrative expenses, principally associated with acquisition accounting; restructuring and other costs/income including costs arising from facility consolidations such as severance and abandoned lease expense and gains and losses from the sale of real estate and product lines as well as from significant litigation-related matters; and amortization of acquisition-related intangible assets. The company uses this measure because it helps management understand and evaluate the segments’ core operating results and facilitates comparison of performance for determining compensation.

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Business Segment Information
 Three Months Ended Three Months Ended
 April 1,
 April 2,
 March 31,
 April 1,
(In millions) 2017
 2016
 2018
 2017
        
Revenues        
Life Sciences Solutions $1,363.5
 $1,217.7
 $1,499
 $1,363
Analytical Instruments 1,052.0
 759.3
 1,257
 1,052
Specialty Diagnostics 866.4
 854.6
 947
 866
Laboratory Products and Services 1,699.0
 1,648.8
 2,413
 1,699
Eliminations (215.9) (185.6) (263) (215)
        
Consolidated revenues 4,765.0
 4,294.8
 5,853
 4,765
        
Segment Income (a)        
Life Sciences Solutions 433.9
 351.3
 517
 433
Analytical Instruments 191.8
 111.7
 246
 192
Specialty Diagnostics 233.9
 230.1
 243
 233
Laboratory Products and Services 216.2
 236.9
 280
 216
        
Subtotal reportable segments (a) 1,075.8
 930.0
 1,286
 1,074
        
Cost of revenues charges (30.9) (10.6) (3) (31)
Selling, general and administrative charges, net (31.5) (28.9) (8) (31)
Restructuring and other costs, net (23.5) (50.6) (45) (24)
Amortization of acquisition-related intangible assets (367.5) (322.0) (444) (368)
        
Consolidated operating income 622.4
 517.9
 786
 620
Other expense, net (b) (119.5) (94.9) (152) (117)
        
Income from continuing operations before income taxes $502.9
 $423.0
 $634
 $503
        
Depreciation        
Life Sciences Solutions $32.7
 $37.0
 $31
 $33
Analytical Instruments 16.9
 9.6
 18
 17
Specialty Diagnostics 17.2
 18.0
 19
 17
Laboratory Products and Services 30.2
 29.5
 63
 30
        
Consolidated depreciation $97.0
 $94.1
 $131
 $97
(a)Represents operating income before certain charges to cost of revenues and selling, general and administrative expenses; restructuring and other costs, net; and amortization of acquisition-related intangibles.
(b)The company does not allocate other expense, net to its segments.

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Geographical Information
  Three Months Ended
  March 31,
 April 1,
(In millions) 2018
 2017
     
Revenues (c)
    
United States $2,756
 $2,377
China 541
 441
Other 2,556
 1,947
     
Consolidated revenues $5,853
 $4,765
(c)Revenues are attributed to countries based on customer location.

Note 4.5.
Other Expense, Net
The components of other expense, net, in the accompanying statement of income are as follows:
 Three Months Ended Three Months Ended
 April 1,
 April 2,
 March 31,
 April 1,
(In millions) 2017
 2016
 2018
 2017
        
Interest Income $18.5
 $10.8
 $20
 $18
Interest Expense (135.4) (106.2) (163) (135)
Other Items, Net (2.6) 0.5
 (9) 
        
Other Expense, Net $(119.5) $(94.9) $(152) $(117)

Other Items, Net
Note 5.
 Stock-based Compensation Expense
The components of stock-based compensation expense are primarilyIn all periods, other items, net includes currency transaction gains and losses on monetary assets and liabilities and net periodic pension benefit cost/income, excluding the service cost component which is included in selling, general and administrativeoperating expenses and are as follows:
  Three Months Ended
  April 1,
 April 2,
(In millions) 2017
 2016
     
Stock Option Awards $10.2
 $10.6
Restricted Unit Awards 22.8
 22.8
     
Total Stock-based Compensation Expense $33.0
 $33.4
Duringon the first three monthsaccompanying statement of 2017, the company made equity compensation grants to employees consisting of 0.7 million service- and performance-based restricted stock units and options to purchase 1.8 million shares.
As of April 1, 2017, there was $105 million of total unrecognized compensation cost related to unvested stock options granted. The cost is expected to be recognized through 2021 with a weighted average amortization period of 2.7 years.
As of April 1, 2017, there was $196 million of total unrecognized compensation cost related to unvested restricted stock unit awards. The cost is expected to be recognized through 2020 with a weighted average amortization period of 2.4 years.income.


THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Note 6.Income Taxes
The provision for income taxes in the accompanying statement of income differs from the provision calculated by applying the statutory federal income tax rate of 35% to income from continuing operations before provision for income taxes due to the following:
 Three Months Ended Three Months Ended
 April 1,
 April 2,
 March 31,
 April 1,
(In millions) 2017
 2016
 2018
 2017
        
Statutory Federal Income Tax Rate 21% 35%
    
Provision for Income Taxes at Statutory Rate $176.0
 $148.1
 $133
 $176
        
Increases (Decreases) Resulting From:        
Foreign rate differential (84.4) (47.3) (19) (84)
Income tax credits (41.4) (77.8) (41) (41)
Manufacturing deduction (7.7) (6.7)
Foreign-derived intangible income (9) 
Singapore tax holiday (4.6) (3.7) (8) (5)
Impact of change in tax laws and apportionment on deferred taxes (62.9) 8.9
 3
 (63)
Nondeductible expenses 2.5
 1.7
Transition tax and other initial impacts of U.S. tax reform 70
 
Provision of tax reserves, net (49) 
Excess tax benefits from stock options and restricted stock units (23.9) 
 (25) (24)
Tax return reassessments and settlements 
 (2.0)
State income taxes, net of federal tax (0.8) (1.5)
Other, net (1.3) 1.0
 
 (7)
        
(Benefit from) Provision for income taxes $(48.5) $20.7
Provision for (benefit from) income taxes $55
 $(48)
The company has operations and a taxable presence in approximately 50 countries outside the U.S. AllSome of these countries except one have a lower tax rate than the U.S. The countries in which the company has a material presence that have significantly lower tax rates than the U.S. include Germany, the Netherlands, Singapore, Sweden, Switzerland and the United Kingdom. The company’s ability to obtain a benefit from lower tax rates outside the U.S. is dependent on its relative levels of income in countries outside the U.S. and on the statutory tax rates in those countries.
The company receives a tax deduction upon exercise of non-qualified stock options by employees, or the vesting of restricted stock units held by employees, for the difference between the exercise price and the market price of the underlying common stock on the date of exercise. Prior to 2017, the amount of the tax deduction in excess of compensation cost recognized was allocated to capital in excess of par value. Beginning in 2017, these excess tax benefits reduce the tax provision as described in Note 1. In the first three monthsquarter of 2017,2018, the company'scompany recorded a net tax provision of $21 million to adjust the estimated initial impacts of U.S. tax reform recorded in 2017, consisting of an incremental provision of $70 million offset in part by a $49 million reduction of related unrecognized tax benefits established in 2017. The adjustment was reduced by $24 millionrequired based on new U.S. Treasury guidance released in the first quarter of such benefits.2018.
The company has significant activities in Singapore and has received considerable tax incentives. The local taxing authority granted the company pioneer company status which provides an incentive encouraging companies to undertake activities that have the effect of promoting economic or technological development in Singapore. This incentive equates to a tax exemption on earnings associated with most of the company’s manufacturing activities in Singapore and continues through December 31, 2026. In 20172018 and 2016,2017, the impact of this tax holiday decreased the annual effective tax rates by 0.9%1.3 percentage points and 0.9%,0.9 percentage point, respectively, and increased diluted earnings per share by approximately $0.01$0.02 and $0.01, respectively. In connection with the
Unrecognized Tax Benefits
As of March 2017 extension of this agreement until 2026,31, 2018, the company recorded a benefithad $1.27 billion of approximately $65 million ($0.16 per diluted share) for the effect on deferred tax balances of the extended tax holiday.
The company’s unrecognized tax benefits decreased to $789 million at April 1, 2017, from $802 million at December 31, 2016. The decrease of $13 million resulted from an adjustment to a prior year amendedwhich, if recognized, would reduce the effective tax filing.rate.




THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

A reconciliation of the beginning and ending amounts of unrecognized tax benefits is as follows:
(In millions) 2018
   
Balance at beginning of year $1,409
Reductions due to acquisitions (9)
Additions for tax positions of current year 1
Additions for tax positions of prior years 1
Reductions for tax positions of prior years (84)
Settlements (45)
   
Balance at end of period $1,273

Note 7.
Earnings per Share
  Three Months Ended
  April 1,
 April 2,
(In millions except per share amounts) 2017
 2016
     
Income from Continuing Operations $551.4
 $402.3
Loss from Discontinued Operations 
 (0.1)
     
Net Income $551.4
 $402.2
     
Basic Weighted Average Shares 391.0
 395.8
Plus Effect of:    
Stock options and restricted units 3.1
 2.9
     
Diluted Weighted Average Shares 394.1
 398.7
     
Basic Earnings per Share:    
Continuing operations $1.41
 $1.02
Discontinued operations 
 
     
Basic Earnings per Share $1.41
 $1.02
     
Diluted Earnings per Share:    
Continuing operations $1.40
 $1.01
Discontinued operations 
 
     
Diluted Earnings per Share $1.40
 $1.01
Options to purchase 2.6 million and 3.6 million shares of common stock were not included in the computation of diluted earnings per share for the first three months of 2017 and 2016, respectively, because their effect would have been antidilutive.
  Three Months Ended
  March 31,
 April 1,
(In millions except per share amounts) 2018
 2017
     
Net Income $579
 $551
     
Basic Weighted Average Shares 402
 391
Plus Effect of:    
Stock options and restricted units 4
 3
     
Diluted Weighted Average Shares 406
 394
     
Basic Earnings per Share $1.44
 $1.41
     
Diluted Earnings per Share $1.43
 $1.40
     
Antidilutive Stock Options Excluded from Diluted Weighted Average Shares 2
 3

18



THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Note 8.
Debt and Other Financing Arrangements
 Effective Interest Rate at April 1,
 April 1,
 December 31,
 Effective Interest Rate at March 31,
 March 31,
 December 31,
(Dollars in millions) 2017
 2017
 2016
 2018
 2018
 2017
            
Commercial Paper 0.34% $1,530.2
 $953.3
 % $1,171
 $960
Term Loan 2.20% 625.0
 825.0
1.85% 5-Year Senior Notes, Due 1/15/2018 

 
 500.0
Floating Rate 2-Year Senior Notes, Due 8/9/2018 (euro-denominated) 0.12% 639.1
 631.0
 0.38% 739
 721
2.15% 3-Year Senior Notes, Due 12/14/2018 2.35% 450.0
 450.0
 

 
 450
2.40% 5-Year Senior Notes, Due 2/1/2019 2.59% 900.0
 900.0
 2.59% 900
 900
Floating Rate 2-Year Senior Notes, Due 7/24/2019 (euro-denominated) 0.09% 616
 600
6.00% 10-Year Senior Notes, Due 3/1/2020 2.97% 750.0
 750.0
 2.97% 750
 750
4.70% 10-Year Senior Notes, Due 5/1/2020 4.23% 300.0
 300.0
 4.23% 300
 300
1.50% 5-Year Senior Notes, Due 12/1/2020 (euro-denominated) 1.62% 452.7
 447.0
 1.62% 524
 510
5.00% 10-Year Senior Notes, Due 1/15/2021 3.24% 400.0
 400.0
 3.24% 400
 400
4.50% 10-Year Senior Notes, Due 3/1/2021 4.57% 1,000.0
 1,000.0
 6.24% 1,000
 1,000
3.60% 10-Year Senior Notes, Due 8/15/2021 4.43% 1,100.0
 1,100.0
 6.06% 1,100
 1,100
3.30% 7-Year Senior Notes, Due 2/15/2022 3.43% 800.0
 800.0
 3.43% 800
 800
2.15% 7-Year Senior Notes, Due 7/21/2022 (euro-denominated) 2.27% 532.6
 525.9
 2.28% 616
 600
3.15% 10-Year Senior Notes, Due 1/15/2023 3.30% 800.0
 800.0
 3.30% 800
 800
3.00% 7-Year Senior Notes Due 4/15/2023 4.64% 1,000.0
 1,000.0
3.00% 7-Year Senior Notes, Due 4/15/2023 6.23% 1,000
 1,000
4.15% 10-Year Senior Notes, Due 2/1/2024 4.16% 1,000.0
 1,000.0
 4.16% 1,000
 1,000
0.75% 8-Year Senior Notes, Due 9/12/2024 (euro-denominated) 0.93% 1,065.2
 1,051.7
 0.95% 1,232
 1,201
2.00% 10-Year Senior Notes, Due 4/15/2025 (euro-denominated) 2.09% 681.7
 673.1
 2.10% 789
 768
3.65% 10-Year Senior Notes, Due 12/15/2025 3.77% 350.0
 350.0
 3.77% 350
 350
1.40% 8.5-Year Senior Notes, Due 1/23/2026 (euro-denominated) 1.53% 863
 840
2.95% 10-Year Senior Notes, Due 9/19/2026 3.19% 1,200.0
 1,200.0
 3.19% 1,200
 1,200
1.45% 10-Year Senior Notes, Due 3/16/2027 (euro-denominated) 1.64% 532.6
 
 1.67% 616
 600
1.375% 12-Year Senior Notes, 9/12/2028 (euro-denominated) 1.46% 639.1
 631.0
3.20% 10-Year Senior Notes, Due 8/15/2027 3.39% 750
 750
1.375% 12-Year Senior Notes, Due 9/12/2028 (euro-denominated) 1.46% 739
 721
1.95% 12-Year Senior Notes, Due 7/24/2029 (euro-denominated) 2.08% 863
 840
2.875% 20-Year Senior Notes, Due 7/24/2037 (euro-denominated) 2.94% 863
 840
5.30% 30-Year Senior Notes, Due 2/1/2044 5.37% 400.0
 400.0
 5.37% 400
 400
4.10% 30-Year Senior Notes, Due 8/15/2047 4.32% 750
 750
Other   12.5
 13.0
   23
 24
            
Total Borrowings at Par Value   17,160.7
 16,701.0
   21,154
 21,175
Fair Value Hedge Accounting Adjustments   (55.5) (49.3)   (120) (70)
Unamortized Premium, Net   40.6
 52.2
Unamortized Discount, Net   (8) (2)
Unamortized Debt Issuance Costs   (75.0) (76.0)   (90) (95)
            
Total Borrowings at Carrying Value   17,070.8
 16,627.9
   20,936
 21,008
Less: Short-term Obligations and Current Maturities   1,882.4
 1,255.5
   2,814
 2,135
            
Long-term Obligations   $15,188.4
 $15,372.4
   $18,122
 $18,873
The effective interest rates for the fixed-rate debt include the stated interest on the notes, the accretion of any discount or amortization of any premium, the amortization of any debt issuance costs and, if applicable, adjustments related to hedging.
See Note 11 for fair value information pertaining to the company’s long-term obligations.
Credit Facilities
The company has a revolving credit facility with a bank group that provides for up to $2.50 billion of unsecured multi-currency revolving credit. The facility expires in July 2021. The agreement calls for interest at either a LIBOR-based rate, a

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

EURIBOR-based rate (for funds drawn in Euro) or a rate based on the prime lending rate of the agent bank, at the company’s option. The agreement contains affirmative, negative and financial covenants, and events of default customary for financingsfacilities of this type. The financial covenants require the company to maintainin our revolving credit facility (the Facility) include a Consolidated Leverage Ratio of debt(total debt-to-Consolidated EBITDA) and a Consolidated Interest Coverage Ratio (Consolidated EBITDA to EBITDA (asConsolidated Interest Expense), as such terms are defined in the agreement) below 4.0 to Facility. Specifically, the company has agreed that, so long as any lender has any commitment under the Facility, any letter of credit is outstanding under the Facility, or any loan or other obligation is outstanding under the Facility, it will maintain a maximum Consolidated Leverage Ratio of 4.0:1.0 forthrough the first two quarterssecond quarter of 20172018 and then stepping down to 3.5 to 3.5:1.0 each fiscal

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

for the third quarter of 2018 and thereafter. The agreementcompany has also requiresagreed that so long as any lender has any commitment under the company toFacility or any letter of credit is outstanding under the Facility, or any loan or other obligation is outstanding under the Facility, it will maintain ana minimum Consolidated Interest Coverage Ratio of EBITDA (as defined in3.0:1.0 as of the agreement) to interest expenselast day of 3.0 to 1.0. The credit agreement permits the company to use the facility for working capital; acquisitions; repurchases of common stock, debentures and other securities; the refinancing of debt; and general corporate purposes. The credit agreement allows for the issuance of letters of credit, which reduces the amount available for borrowing. If the company borrows under this facility, it intends to leave undrawn an amount equivalent to outstanding commercial paper to provide a source of funds in the event that commercial paper markets are not available.any fiscal quarter. As of April 1, 2017,March 31, 2018, no borrowings were outstanding under the facility,Facility, although available capacity was reduced by approximately $73$75 million as a result of outstanding letters of credit.
Commercial Paper Programs
The company has commercial paper programs pursuant to which it may issue and sell unsecured, short-term promissory notes (CP Notes). Under the U.S. program, a) maturities may not exceed 397 days from the date of issue and b) the CP Notes are issued on a private placement basis under customary terms in the commercial paper market and are not redeemable prior to maturity nor subject to voluntary prepayment. Under the euro program, maturities may not exceed 183 days and may be denominated in euro, U.S. dollars, Japanese yen, British pounds sterling, Swiss franc, Canadian dollars or other currencies. Under both programs, the CP Notes are issued at a discount from par (or premium to par, in the case of negative interest rates), or, alternatively, are sold at par and bear varying interest rates on a fixed or floating basis. As of April 1, 2017,March 31, 2018, outstanding borrowings under these programs were $1.53$1.17 billion, with a weighted average remaining period to maturity of 7150 days and are classified as short-term obligations in the accompanying balance sheet.
Term Loan
In 2016, in connection with the acquisition of FEI, the company entered into a term loan agreement. The term loan agreement is a 3-year unsecured $2.00 billion term loan facility. The agreement calls for interest at either a LIBOR-based rate, a EURIBOR-based rate (for funds drawn under the term loan in Euro) or a rate based on the prime lending rate of the agent bank, at the company’s option. The agreements contain affirmative, negative and financial covenants, and events of default customary for financings of this type. The financial covenants are consistent with those in the revolving credit facility described above.
Senior Notes
Interest on the floating rate senior notes is payable quarterly. Interest is payable annually on the other euro-denominated senior notes and semi-annually on all other senior notes. Each of the notes may be redeemed at a redemption price of 100% of the principal amount plus a specified make-whole premium plus accrued interest. The company is subject to certain affirmative and negative covenants under the indentures governing the senior notes, the most restrictive of which limits the ability of the company to pledge principal properties as security under borrowing arrangements.
Thermo Fisher Scientific (Finance I) B.V., a wholly-owned finance subsidiary of the company issued the Floating Rate Senior Notes due 2018 included in the table above. This subsidiary has no independent function other than financing activities. The Floating Rate Senior Notes due 2018 are fully and unconditionally guaranteed by the company and no other subsidiaries of the company have guaranteed the obligations.
Interest Rate Swap Arrangements
The company has entered into LIBOR-based interest rate swap arrangements with various banks on several of its outstanding senior notes. The aggregate amounts of the swaps are equal to the principal amounts of the notes and the payment dates of the swaps coincide with the interest payment dates of the notes. The swap contracts provide for the company to pay a variable interest rate and receive a fixed rate. The variable interest rates reset monthly. The swaps have been accounted for as fair value hedges of the notes. See Note 11 for additional information. The following table summarizes the outstanding interest rate swap arrangements on the company's senior notes at April 1, 2017:March 31, 2018:
 Aggregate Notional Amount
 Pay Rate as of
   Aggregate Notional Amount
 Pay Rate as of
  
(Dollars in millions) Pay Rate April 1,
2017

 Receive Rate
 Pay Rate March 31,
2018

 Receive Rate
            
4.50% Senior Notes due 2021 1,000.0
 1-month LIBOR + 3.4420% 4.2264% 4.50% 1,000
 1-month LIBOR + 3.4420% 5.1062% 4.50%
3.60% Senior Notes due 2021 1,100.0
 1-month LIBOR + 2.5150% 3.4272% 3.60% 1,100
 1-month LIBOR + 2.5150% 4.2916% 3.60%
3.00% Senior Notes due 2023 1,000.0
 1-month LIBOR + 1.7640% 2.6762% 3.00% 1,000
 1-month LIBOR + 1.7640% 3.5406% 3.00%


THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Note 9.
Commitments and Contingencies
Environmental Matters
The company is currently involved in various stages of investigation and remediation related to environmental matters. The company cannot predict all potential costs related to environmental remediation matters and the possible impact on future operations given the uncertainties regarding the extent of the required cleanup, the complexity and interpretation of applicable laws and regulations, the varying costs of alternative cleanup methods and the extent of the company’s responsibility. Expenses for environmental remediation matters related to the costs of installing, operating and maintaining groundwater-treatment systems and other remedial activities related to historical environmental contamination at the company’s domestic and international facilities were not material in any period presented. The company records accruals for environmental remediation liabilities, based on current interpretations of environmental laws and regulations, when it is probable that a liability has been incurred and the amount of such liability can be reasonably estimated. The company calculates estimates based upon several factors, including reports prepared by environmental specialists and management’s knowledge of and experience with these environmental matters. The company includes in these estimates potential costs for investigation, remediation and operation and maintenance of cleanup sites. At April 1, 2017,March 31, 2018, the company’s total environmental liability was approximately $43$61 million. While management believes the accruals for environmental remediation are adequate based on current estimates of remediation costs, the company may be subject to additional remedial or compliance costs due to future events such as changes in existing laws and regulations, changes in agency direction or enforcement policies, developments in remediation technologies or changes in the conduct of the company’s operations, which could have a material adverse effect on the company’s financial position, results of operations or cash flows.
Litigation and Related Contingencies
There are various lawsuits and claims pending against the company including matters involving product liability, intellectual property, employment and commercial issues. The company determines the probability and range of possible loss based on the current status of each of these matters. A liability is recorded in the financial statements if it is believed to be probable that a loss has been incurred and the amount of the loss can be reasonably estimated. The company establishes a liability that is an estimate of amounts expected to be paid in the future for events that have already occurred. The company accrues the most likely amount or at least the minimum of the range of probable loss when a range of probable loss can be estimated. The accrued liabilities are based on management’s judgment as to the probability of losses for asserted and unasserted claims and, where applicable, actuarially determined estimates. Accrual estimates are adjusted as additional information becomes known or payments are made. The amount of ultimate loss may differ from these estimates. Due to the inherent uncertainties associated with pending litigation or claims, the company cannot predict the outcome, nor, with respect to certain pending litigation or claims where no liability has been accrued, make a meaningful estimate of the reasonably possible loss or range of loss that could result from an unfavorable outcome. The company has no material accruals for pending litigation or claims for which accrual amounts are not disclosed below or in the company's 20162017 financial statements and notes included in the company's Annual Report on Form 10-K filed with the SEC, nor are material losses deemed probable for such matters. It is reasonably possible, however, that an unfavorable outcome that exceeds the company’s current accrual estimate, if any, for one or more of the matters described below could have a material adverse effect on the company’s results of operations, financial position and cash flows.
Product Liability, Workers Compensation and Other Personal Injury Matters
For product liability, workers compensation and other personal injury matters, the company accrues the most likely amount or at least the minimum of the range of possible loss when a range of possible loss can be estimated. The company records estimated amounts due from insurers related to certain product liabilities as an asset. Although the company believes that the amounts accrued and estimated recoveries are probable and appropriate based on available information, including actuarial studies of loss estimates, the process of estimating losses and insurance recoveries involves a considerable degree of judgment by management and the ultimate amounts could vary materially. Insurance contracts do not relieve the company of its primary obligation with respect to any losses incurred. The collectability of amounts due from its insurers is subject to the solvency and willingness of the insurer to pay, as well as the legal sufficiency of the insurance claims. Management monitors the payment history as well as the financial condition and ratings of its insurers on an ongoing basis.
Intellectual Property Matters
On July 13 and 15, 2015, 454 Life Sciences (a member of the Roche Group) filed complaints against Ion Torrent Systems, Inc., Life Technologies Corp., and Thermo Fisher Scientific Inc. in the United States District Court for the District of Delaware and in Germany. Plaintiff alleged infringement of patents relating to methods of analyzing nucleic acid sequences using emulsion amplification, which plaintiff alleged are impermissibly used in Ion Torrent sequencing workflows. In March 2017,

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

the parties reached a settlement of this litigation pursuant to which the company licensed the related technology from 454 Life Sciences for $25 million in cash and granted plaintiff's parent a license to certain company technology.
On June 6, 2004, Enzo Biochem, Enzo Life Sciences and Yale University filed a complaint against Life Technologies in United States District Court for the District of Connecticut. The plaintiffs allege patent infringement by Applera’s labeled DNA terminator products used in DNA sequencing and fragment analysis. The plaintiff sought damages for alleged willful infringement, attorneys’ fees, costs, prejudgment interest, and injunctive relief. In November 2012, the jury awarded damages of $49 million. Prejudgment interest of $12 million was also granted. The $61 million judgment and interest was accrued by Life Technologies and the liability was assumed by the company as of the date of the acquisition. In March 2015 the United States Court of Appeals for the Federal Circuit vacated the judgment and returned the case to the District Court for further proceedings. In February 2016, the District Court granted the company’s motion for summary judgment of non-infringement and entered judgment in its favor. Enzo appealed that decision to the Federal Circuit in March 2016. The company has maintained the $61 million accrual, pending appeals.
On May 26, 2010, Promega Corp. & Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften EV filed a complaint against Life Technologies in the United States District Court for the Western District of Wisconsin. The plaintiffs allege patent infringement by sales and uses of Applied Biosystems’ short tandem repeat DNA identification products outside the scope of a

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

2006 license agreement. The plaintiff sought damages for alleged willful infringement, attorneys’ fees, costs, prejudgment interest, and injunctive relief. Although a jury initially found willful infringement and assessed damages at $52 million the District Court subsequently overturned the verdict on the grounds that the plaintiff had failed to prove infringement. The District Court entered judgment in favor of Life Technologies; and plaintiffs and Life Technologies filed cross-appeals with the United States Court of Appeals for the Federal Circuit. The $52 million award was accrued by Life Technologies and the liability was assumed by the company as of the date of the acquisition. On December 15, 2014, the Court of Appeals issued a decision invalidating four of the plaintiffs’ patents, but finding infringement by Life Technologies of the remaining fifth patent. The Court of Appeals also ordered a new trial on damages in the District Court. Life Technologies' petition to the U.S. Supreme Court seeking review of the Court of Appeals’ judgment was granted on June 27, 2016, and the case was stayed in the District Court pending the outcome of the Supreme Court’s review. On February 22, 2017, the Supreme Court issued a decision reversing the Court of Appeals’ judgment and remanding the case to the Court of Appeals for further proceedings in view of the Supreme Court’s legal interpretation of the patent law statute in question. On November 13, 2017, the Court of Appeals issued a decision holding that Promega is not entitled to recover any damages and affirming the District Court’s grant of judgment in favor of Life Technologies and denial of Promega’s motion for a new trial. The Court of Appeals denied Promega’s petition for rehearing on February 14, 2018, and Promega has 90 days therefrom to file a petition with the U.S. Supreme Court seeking review of the Court of Appeals' decision. The company has maintained the $52 million accrual, pending conclusion of this matter.
On December 27, 2011, Illumina Inc. filed a complaint against Life Technologies in the United States District Court for the Southern District of California alleging infringement of a patent relating to methods for making bead arrays by Ion Torrent’s semiconductor sequencing systems. Plaintiff sought damages for alleged willful infringement, attorneys’ fees, costs, pre- and post-judgment interest, and injunctive relief. In April 2017, the companies executed a settlement agreement resolving this litigation for immaterial financial terms.
On June 3, 2013, Unisone Strategic IP filed a complaint against Life Technologies in the United States District Court for the Southern District of California alleging patent infringement by Life Technologies’ supply chain management system software, which operates with product “supply centers”"supply centers" installed at customer sites. Plaintiff seeks damages for alleged willful infringement, attorneys’ fees, costs, and injunctive relief.
Commercial Matters
On May 5, 2015,August 24, 2017, Unisone filed an appeal from a decision by the Patent Trial and February 12, 2016,Appeal Board that found the Academy of Allergy & Asthma in Primary Care and United Biologics, LLC d/b/a United Allergy Services, a provider of on-site services to physicians in the delivery of testing and treatment of allergies, filed a complaint against Phadia U.S. Inc. (a subsidiary of the company) and Thermo Fisher Scientific Inc., respectively, in the United States District Court for the Western District of Texas. The plaintiffs allege variouschallenged patent claims of anticompetitive activities in violation of antitrust laws, tortious interference with contracts and existing and prospective business relations, and civil conspiracy. On March 28, 2016, the company filed a counterclaim against United Biologics, LLC alleging tortious interference with business relations and seeking a declaratory judgment and injunctive relief. The plaintiffs seek damages, attorneys’ fees, costs, and injunctive relief. The company expects this matter will be scheduled for trial in 2017.invalid.


THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Note 10.
Comprehensive Income and Shareholders' Equity
Comprehensive Income (Loss)
Comprehensive income (loss) combines net income and other comprehensive items. Other comprehensive items represent certain amounts that are reported as components of shareholders’ equity in the accompanying balance sheet.
Changes in each component of accumulated other comprehensive items, net of tax are as follows: 
(In millions) Currency
Translation
Adjustment

 Unrealized
Gains on
Available-for-
Sale
Investments

 Unrealized
Losses on
Hedging
Instruments

 Pension and
Other
Postretirement
Benefit
Liability
Adjustment

 Total
 Currency
Translation
Adjustment

 Unrealized
Losses on
Available-for-
Sale
Investments

 Unrealized
Losses on
Hedging
Instruments

 Pension and
Other
Postretirement
Benefit
Liability
Adjustment

 Total
                    
Balance at December 31, 2016 $(2,343.4) $0.9
 $(57.1) $(236.7) $(2,636.3)
Balance at December 31, 2017 $(1,755) $(1) $(50) $(197) $(2,003)
Cumulative effect of accounting changes (Note 1) (54) 1
 (11) (24) (88)
          
Other comprehensive income (loss) before reclassifications 160.0
 1.1
 
 (2.0) 159.1
 47
 
 
 (2) 45
Amounts reclassified from accumulated other comprehensive items 
 
 1.8
 1.9
 3.7
 
 
 2
 2
 4
                    
Net other comprehensive items 160.0
 1.1
 1.8
 (0.1) 162.8
 47
 
 2
 
 49
                    
Balance at April 1, 2017 $(2,183.4) $2.0
 $(55.3) $(236.8) $(2,473.5)
Balance at March 31, 2018 $(1,762) $
 $(59) $(221) $(2,042)


THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Note 11.Fair Value Measurements and Fair Value of Financial Instruments
Fair Value Measurements
The company uses the market approach technique to value its financial instruments and there were no changes in valuation techniques during 2017.2018. The company’s financial assets and liabilities carried at fair value are primarily comprised of insurance contracts, investments in money market funds, derivative contracts, mutual funds holding publicly traded securities and other investments in unit trusts held as assets to satisfy outstanding deferred compensation and retirement liabilities; and acquisition-related contingent consideration.
The fair value accounting guidance requires that assets and liabilities carried at fair value be classified and disclosed in one of the following three categories:
Level 1: Quoted market prices in active markets for identical assets or liabilities that the company has the ability to access.
Level 2: Observable market based inputs or unobservable inputs that are corroborated by market data such as quoted prices, interest rates and yield curves.
Level 3: Inputs are unobservable data points that are not corroborated by market data.

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

The following tables present information about the company’s financial assets and liabilities measured at fair value on a recurring basis as of April 1, 2017March 31, 2018 and December 31, 2016:2017:
 April 1,
 Quoted
Prices in
Active
Markets

 Significant
Other
Observable
 Inputs

 Significant
Unobservable
Inputs

 March 31,
 Quoted
Prices in
Active
Markets

 Significant
Other
Observable
 Inputs

 Significant
Unobservable
Inputs

(In millions) 2017
 (Level 1)
 (Level 2)
 (Level 3)
 2018
 (Level 1)
 (Level 2)
 (Level 3)
                
Assets                
Cash equivalents $75.6
 $75.6
 $
 $
 $36
 $36
 $
 $
Bank time deposits 2.0
 2.0
 
 
 2
 2
 
 
Investments in mutual funds and other similar instruments 16.0
 16.0
 
 
 13
 13
 
 
Warrants 3.1
 
 3.1
 
 2
 
 2
 
Insurance contracts 104.4
 
 104.4
 
 115
 
 115
 
Derivative contracts 11.6
 
 11.6
 
 7
 
 7
 
                
Total Assets $212.7
 $93.6
 $119.1
 $
 $175
 $51
 $124
 $
                
Liabilities                
Derivative contracts $133.7
 $
 $133.7
 $
 $165
 $
 $165
 $
Contingent consideration 40.7
 
 
 40.7
 41
 
 
 41
                
Total Liabilities $174.4
 $
 $133.7
 $40.7
 $206
 $
 $165
 $41

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

 December 31,
 Quoted
Prices in
 Active
Markets

 Significant
Other
Observable
 Inputs

 Significant
 Unobservable
 Inputs

 December 31,
 Quoted
Prices in
 Active
Markets

 Significant
Other
Observable
 Inputs

 Significant
 Unobservable
 Inputs

(In millions) 2016
 (Level 1)
 (Level 2)
 (Level 3)
 2017
 (Level 1)
 (Level 2)
 (Level 3)
                
Assets                
Cash equivalents $64.8
 $64.8
 $
 $
 $22
 $22
 $
 $
Bank time deposits 2.0
 2.0
 
 
 2
 2
 
 
Investments in mutual funds and other similar instruments 15.5
 15.5
 
 
 13
 13
 
 
Warrants 2.0
 
 2.0
 
 2
 
 2
 
Insurance contracts 102.1
 
 102.1
 
 116
 
 116
 
Derivative contracts 15.8
 
 15.8
 
 10
 
 10
 
                
Total Assets $202.2
 $82.3
 $119.9
 $
 $165
 $37
 $128
 $
                
Liabilities                
Derivative contracts $121.9
 $
 $121.9
 $
 $139
 $
 $139
 $
Contingent consideration 3.4
 
 
 3.4
 35
 
 
 35
                
Total Liabilities $125.3
 $
 $121.9
 $3.4
 $174
 $
 $139
 $35
The company determines the fair value of its insurance contracts by obtaining the cash surrender value of the contracts from the issuer. The fair value of derivative contracts is the estimated amount that the company would receive/pay upon liquidation of the contracts, taking into account the change in interest rates and currency exchange rates. The company determines the fair value of acquisition-related contingent consideration based on assessment of the probability that the company would be required to makeprobability-weighted discounted cash flows associated with such future payment.payments. Changes to the fair value of contingent consideration are recorded in selling, general and administrative expense. The following table provides a rollforward of the fair value, as determined by level 3 inputs, of the contingent consideration.
  Three Months Ended
  March 31,
 April 1,
(In millions) 2018
 2017
     
Contingent Consideration    
Beginning Balance $35
 $6
Acquisitions 11
 9
Payments (5) 
Change in fair value included in earnings 
 25
     
Ending Balance $41
 $40
Derivative Contracts
As of both March 31, 2018 and December 31, 2017, the total notional amount of outstanding interest rate swaps was $3.10 billion. These swap arrangements are described in Note 8. The notional amounts of derivative contracts outstanding, consisting of interest rate swaps and currency exchange contracts outstanding totaled $6.03$2.98 billion and $6.70$2.92 billion at April 1, 2017March 31, 2018 and December 31, 2016,2017, respectively.

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

While certain derivatives are subject to netting arrangements with counterparties, the company does not offset derivative assets and liabilities within the consolidated balance sheet. The following tables present the fair value of derivative instruments in the consolidated balance sheet and statement of income.
 Fair Value – Assets Fair Value – Liabilities Fair Value – Assets Fair Value – Liabilities
 April 1,
 December 31,
 April 1,
 December 31,
 March 31,
 December 31,
 March 31,
 December 31,
(In millions) 2017
 2016
 2017
 2016
 2018
 2017
 2018
 2017
                
Derivatives Designated as Hedging InstrumentsDerivatives Designated as Hedging Instruments       Derivatives Designated as Hedging Instruments       
Interest rate swaps (a) $
 $
 $115.8
 $109.5
 $
 $
 $162
 $124
Derivatives Not Designated as Hedging InstrumentsDerivatives Not Designated as Hedging Instruments       Derivatives Not Designated as Hedging Instruments       
Currency exchange contracts (b) 11.6
 15.8
 17.9
 12.4
 7
 10
 3
 15
        
Total Derivatives $7
 $10
 $165
 $139
(a)The fair value of the interest rate swaps is included in the consolidated balance sheet under the caption other long-term liabilities.
(b)The fair value of the currency exchange contracts is included in the consolidated balance sheet under the captions other current assets or other accrued expenses.
The following amounts related to cumulative basis adjustments for fair value hedges were included in the consolidated balance sheet under the caption long-term obligations:
  Gain (Loss) Recognized
  Three Months Ended
  April 1,
 April 2,
(In millions) 2017
 2016
     
Derivatives Designated as Fair Value Hedges    
Interest rate swaps - effective portion $2.4
 $7.5
Interest rate swaps - ineffective portion 3.0
 
Derivatives Not Designated as Hedging Instruments    
Currency exchange contracts    
Included in cost of revenues $(1.4) $(7.5)
Included in other expense, net 19.2
 (23.4)
  Carrying Amount of the Hedged Liability Cumulative Amount of Fair Value Hedging Adjustment - Increase (Decrease) Included in Carrying Amount of Liability (c)
  March 31,
 December 31,
 March 31,
 December 31,
(In millions) 2018
 2017
 2018
 2017
         
Long-term Obligations $3,261
 $3,309
 $(120) $(70)
(c)Includes increases in the carrying amount of $40 million and $43 million at March 31, 2018 and December 31, 2017, respectively, on discontinued hedging relationships.
  Gain (Loss) Recognized
  Three Months Ended
  March 31,
 April 1,
(In millions) 2018
 2017
     
Fair Value Hedging Relationships    
Interest rate swaps    
Hedged long-term obligations - included in other expense, net $(38) $(6)
Derivatives designated as hedging instruments - included in other expense, net 42
 3
Derivatives Designated as Cash Flow Hedges    
Interest rate swaps    
Amount reclassified from accumulated other comprehensive items to other expense, net (3) (3)
Derivatives Designated as Net Investment Hedges    
Foreign currency-denominated debt    
Included in currency translation adjustment within other comprehensive items (200) (46)
Derivatives Not Designated as Hedging Instruments    
Currency exchange contracts    
Included in cost of revenues (2) (1)
Included in other expense, net (8) 19

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Gains and losses recognized on currency exchange contracts and the effective portion of interest rate swaps designated as fair value hedges are included in the consolidated statement of income together with the corresponding, offsetting losses and gains on the underlying hedged transactions. Gains and losses recognized on the ineffective portion of interest rate swaps are included in other expense, net in the accompanying statement of income.
The company also uses foreign currency-denominated debt to partially hedge its net investments in foreign operations against adverse movements in exchange rates. The company’s euro-denominated senior notes have been designated as, and are effective as, economic hedges of part of the net investment in a foreign operation. Accordingly, foreign currency transaction gains or losses due to spot rate fluctuations on the euro-denominated debt instruments are included in currency translation adjustment within other comprehensive incomeitems and shareholders’ equity. In
See Note 1 to the first three months ofconsolidated financial statements for 2017 and 2016, pre-tax net gains/(losses) of $(47) million and $(83) million, respectively, from the euro-denominated notes were included in currency translation adjustment.

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

the company's Annual Report on Form 10-K for additional information on the company's risk management objectives and strategies.
Fair Value of Other Financial Instruments
The carrying value and fair value of the company’s notes receivable and debt obligations are as follows:
 April 1, 2017 December 31, 2016 March 31, 2018 December 31, 2017
 Carrying
 Fair
 Carrying
 Fair
 Carrying
 Fair
 Carrying
 Fair
(In millions) Value
 Value
 Value
 Value
 Value
 Value
 Value
 Value
                
Notes Receivable $29.4
 $32.0
 $26.2
 $28.4
 $94
 $99
 $89
 $93
                
Debt Obligations:                
Senior notes $14,904.5
 $15,342.4
 $14,838.3
 $15,184.4
 $19,742
 $20,053
 $20,024
 $20,639
Term loan 623.6
 625.0
 823.3
 825.0
Commercial paper 1,530.2
 1,530.2
 953.3
 953.3
 1,171
 1,171
 960
 960
Other 12.5
 12.5
 13.0
 13.0
 23
 23
 24
 24
                
 $17,070.8
 $17,510.1
 $16,627.9
 $16,975.7
 $20,936
 $21,247
 $21,008
 $21,623
The fair value of debt obligations was determined based on quoted market prices and on borrowing rates available to the company at the respective period ends which represent level 2 measurements.

Note 12.
Supplemental Cash Flow Information
  Three Months Ended
  April 1,
 April 2,
(In millions) 2017
 2016
     
Non-cash Activities    
Fair value of assets of acquired businesses $376.5
 $1,669.0
Cash paid for acquired businesses (311.8) (1,109.4)
     
Liabilities assumed of acquired businesses $64.7
 $559.6
     
Declared but unpaid dividends $59.9
 $60.3
     
Issuance of stock upon vesting of restricted stock units $34.3
 $44.5
  Three Months Ended
  March 31,
 April 1,
(In millions) 2018
 2017
     
Non-cash Investing and Financing Activities    
Declared but unpaid dividends $69
 $60
     
Issuance of stock upon vesting of restricted stock units 61
 34

THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Cash, cash equivalents and restricted cash is included in the consolidated balance sheet as follows:
 April 1,
 December 31,
 March 31,
 December 31,
(In millions) 2017
 2016
 2018
 2017
        
Cash and Cash Equivalents $713.3
 $786.2
 $950
 $1,335
Restricted Cash Included in Other Current Assets 20.2
 18.0
 23
 24
Restricted Cash Included in Other Assets 3.4
 6.6
 2
 2
        
Cash, Cash Equivalents and Restricted Cash $736.9
 $810.8
 $975
 $1,361
Amounts included in restricted cash represent funds held as collateral for bank guarantees and incoming cash in China awaiting government administrative clearance.


THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Note 13.
Restructuring and Other Costs, Net
Restructuring and other costs in the first three months of 20172018 included continuing charges for headcount reductions and facility consolidations in an effort to streamline operations, including the closure and consolidation of operations within several facilities in the U.S., Europe and Asia;Europe; third-party transaction/integration costs to achieve synergies related to acquisitions, including severance and abandoned facility costs; third-partythe acquisition transaction and integration costs primarily associated with the acquisitions of FEI and Affymetrix; charges for changes in estimates of acquisition contingent consideration;Patheon; sales of inventories revalued at the date of acquisition; and net charges for litigation matters. In the first three months of 2017,2018, severance actions associated with facility consolidations and cost reduction measures affected less than 1% of the company’s workforce.
As of May 5, 2017,4, 2018, the company has identified restructuring actions that will result in additional charges of approximately $95$105 million, primarily in 20172018 and 2018,2019, which will be recorded when specified criteria are met, such as communication of benefit arrangements and abandonment of leased facilities.
First Three MonthsQuarter of 20172018
During the first three monthsquarter of 2017,2018, the company recorded net restructuring and other costs by segment as follows:
(In millions) Cost of
Revenues

 Selling,
General and
Administrative
Expenses

 Restructuring
and Other
Costs, Net

 Total
 Cost of
Revenues

 Selling,
General and
Administrative
Expenses

 Restructuring
and Other
Costs, Net

 Total
                
Life Sciences Solutions $0.3
 $27.8
 $15.3
 $43.4
 $
 $
 $13
 $13
Analytical Instruments 30.6
 3.6
 6.4
 40.6
 
 
 17
 17
Specialty Diagnostics 
 
 1.3
 1.3
 
 
 4
 4
Laboratory Products and Services 
 0.1
 0.5
 0.6
 3
 7
 10
 20
Corporate 
 
 
 
 
 1
 1
 2
                
 $30.9
 $31.5
 $23.5
 $85.9
 $3
 $8
 $45
 $56
The principal components of net restructuring and other costs by segment are as follows:
Life Sciences Solutions
In the first three monthsquarter of 2017,2018, the Life Sciences Solutions segment recorded $43$13 million of net restructuring and other charges. The segment recorded $28 million of charges, to selling, general and administrative expenses, principally charges for changes in estimates of acquisition contingent consideration. In addition, the segment recorded $15 million of restructuring and other costs, including $9 million of severance and related costs primarily to achieve acquisition synergies, $3 million of abandoned facilities costs principally for the consolidation of facilities in the U.S, and $3 million of charges for litigation-related matters and severance due to employees of an acquired business at acquired businesses.the date of acquisition.
Analytical Instruments
In the first three monthsquarter of 2017,2018, the Analytical Instruments segment recorded $41$17 million of net restructuring and other charges. The segment recorded charges, to costprimarily abandoned facilities costs associated with the remediation and closure of revenues of $31 million fora manufacturing facility in the sales of inventory revalued at the date of acquisition; $4 million of charges to selling, general, and administrative expense for third-party transaction costs related to recent acquisitions; and $6 million of restructuring and other costs, primarily for severance and other costs to achieve acquisition synergies.U.S.

28



THERMO FISHER SCIENTIFIC INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (Continued)
(Unaudited)

Specialty Diagnostics
In the first quarter of 2018, the Specialty Diagnostics segment recorded $4 million of net restructuring and other charges for severance and other costs associated with facility consolidations in the U.S. and Europe.
Laboratory Products and Services
In the first quarter of 2018, the Laboratory Products and Services segment recorded $20 million of net restructuring and other charges. The segment recorded $3 million of charges to cost of revenues for sales of inventories revalued at the date of acquisition, as well as $7 million of charges to selling, general, and administrative expenses for third-party transaction/integration costs related to the acquisition of Patheon. The segment also recorded $10 million of restructuring and other costs, primarily for employee severance, as well as hurricane response costs.
Corporate
In the first quarter of 2018, the company's corporate operations recorded $2 million of net restructuring and other charges primarily for severance.
The following table summarizes the cash components of the company’s restructuring plans. The non-cash components and other amounts reported as restructuring and other costs, net, in the accompanying statement of income have been summarized in the notes to the tables. Accrued restructuring costs are included in other accrued expenses in the accompanying balance sheet.
(In millions) Severance
 
Abandonment
of Excess
Facilities

 Other (a)
 Total
         
Balance at December 31, 2016 $38.2
 $31.9
 $2.2
 $72.3
Costs incurred in 2017 (c) 14.9
 4.8
 1.6
 21.3
Reserves reversed (b) (3.0) 
 (0.2) (3.2)
Payments (21.1) (10.0) (1.3) (32.4)
Currency translation 0.1
 
 
 0.1
         
Balance at April 1, 2017 $29.1
 $26.7
 $2.3
 $58.1
(In millions) Severance
 
Abandonment
of Excess
Facilities

 Other (a)
 Total
         
Balance at December 31, 2017 $30
 $40
 $6
 $76
Costs incurred in 2018 (c) 19
 16
 4
 39
Reserves reversed (b) (3) (1) 
 (4)
Payments (10) (8) (5) (23)
         
Balance at March 31, 2018 $36
 $47
 $5
 $88
(a)Other includes relocation and moving expenses associated with facility consolidations, as well as employee retention costs which are accrued ratably over the period through which employees must work to qualify for a payment.
(b)Represents reductions in cost of plans.
(c)Excludes $5$10 million of charges, net, primarily associated with litigation-related matters.matters, hurricane response costs, and non-cash compensation due at an acquired business.
The company expects to pay accrued restructuring costs as follows: severance, employee-retention obligations and other costs, primarily through 2017;2018; and abandoned-facility payments, over lease terms expiring through 2027.


THERMO FISHER SCIENTIFIC INC.

Item 2.Management’s Discussion and Analysis of Financial Condition and Results of Operations
Forward-looking statements, within the meaning of Section 21E of the Securities Exchange Act of 1934 are made throughout this Management’s Discussion and Analysis of Financial Condition and Results of Operations. Any statements contained herein that are not statements of historical fact may be deemed to be forward-looking statements, including without limitation statements regarding: projections of revenue, expenses, earnings, margins, tax rates, tax provisions, cash flows, pension and benefit obligations and funding requirements, our liquidity position; cost reductions, restructuring activities, new product and service developments, competitive strengths or market position, acquisitions or divestitures; growth, declines and other trends in markets we sell into; new or modified laws, regulations and accounting pronouncements; outstanding claims, legal proceedings, tax audits and assessments and other contingent liabilities; foreign currency exchange rates and fluctuations in those rates; general economic and capital markets conditions; the timing of any of the foregoing; assumptions underlying any of the foregoing; and any other statements that address events or developments that Thermo Fisher intends or believes will or may occur in the future. Without limiting the foregoing, the words “believes,” “anticipates,” “plans,” “expects,” “seeks,” “estimates,”"believes," "anticipates," "plans," "expects," "seeks," "estimates," and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements are accompanied by such words. While the company may elect to update forward-looking statements in the future, it specifically disclaims any obligation to do so, even if the company’s estimates change, and readers should not rely on those forward-looking statements as representing the company’s views as of any date subsequent to the date of the filing of this Quarterly Report.
A number of important factors could cause the results of the company to differ materially from those indicated by such forward-looking statements, including those detailed under the heading “Risk Factors”"Risk Factors" in Part II, Item 1A of this report on Form 10-Q.
Overview
The company develops, manufactures and sells a broad range of products that are sold worldwide. The company expands the product lines and services it offers by developing and commercializing its own technologies and by making strategic acquisitions of complementary businesses. The company’s continuing operations fall into four business segments (see Note 3)4): Life Sciences Solutions, Analytical Instruments, Specialty Diagnostics and Laboratory Products and Services.
In January 2017, in connection with a change in management responsibility for certain product lines, the company transferred its plastics for cell culture and vaccines/biologics; sample preparation and analysis; and production chemicals product lines to the Life Sciences Solutions segment from the Laboratory Products and Services segment and transferred its biochemical product line from the Life Sciences Solutions segment to the Laboratory Products and Services segment. These moves are consistent with the company’s historical practice of moving a product line between segments when a shift in strategic focus of either the product line or a segment more closely aligns the product line with a segment different than that in which it had previously been reported. Prior period segment information has been reclassified to reflect these transfers.
Recent Acquisitions
The company’s strategy is to augment internal growth at existing businesses with complementary acquisitions. The company’s principal recent acquisitions and divestitures are described below.
On March 31, 2016, the company acquired, primarily within the Life Sciences Solutions segment, Affymetrix, Inc., a North America-based provider of cellular and genetic analysis products, for a total purchase price of $1.34 billion, net of cash acquired, including the assumption of $254 million of debt. The acquisition expanded the company's existing portfolio of antibodies and assays for flow cytometry and single-cell biology applications. Additionally, the acquisition expanded the company's genetic analysis portfolio through the addition of microarrays. Revenues of Affymetrix were $360 million in 2015.
On September 19, 2016, the company acquired, within the Analytical Instruments segment, FEI Company, a North America-based provider of high-performance electron microscopy, for a total purchase price of $4.08 billion, net of cash acquired. The acquisition strengthened the company's analytical instrument portfolio with the addition of high-end electron microscopes. Revenues of FEI were $930 million in 2015.
On February 14, 2017, the company acquired, within the Life Sciences Solutions segment, Finesse Solutions, Inc., a North America-based developer of scalable control automation systems and software for bioproduction, for a total purchase price of $220$221 million, net of cash acquired. The acquisition expanded the company's bioproduction offerings. Revenues of Finesse Solutions were approximately $50 million in 2016.
On March 2, 2017, the company acquired, within the Analytical Instruments segment, Core Informatics, a North America-based provider of cloud-based platforms supporting scientific data management, for a total purchase price of $94 million, net of

29



THERMO FISHER SCIENTIFIC INC.

cash acquired. The acquisition enhanced the company's existing informatics solutions. Revenues of Core Informatics were approximately $10 million in 2016.
On August 29, 2017, the company acquired, within the Laboratory Products and Services segment, substantially all of the issued and outstanding shares of Patheon N.V., a leading global provider of high-quality drug development and delivery solutions to the pharmaceutical and biopharma sectors, for $35.00 per share in cash, or $7.36 billion, including the assumption of net debt. The company financed the purchase price, including the repayment of indebtedness of Patheon, with issuances of debt and equity.
Patheon provides comprehensive, integrated and highly customizable solutions as well as the expertise to help biopharmaceutical companies of all sizes satisfy complex development and manufacturing needs. The acquisition provided entry into the pharmaceutical contract development and manufacturing organization market and added a complementary service to the company's existing pharmaceutical services portfolio. Patheon's revenues totaled $1.87 billion for the year ended October 31, 2016.

30



THERMO FISHER SCIENTIFIC INC.
MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
AND RESULTS OF OPERATIONS

Overview of Results of Operations and Liquidity
 Three Months Ended Three Months Ended
 April 1, April 2, March 31, April 1,
(Dollars in millions) 2017 2016 2018 2017
                
Revenues                
Life Sciences Solutions $1,363.5
 28.6 % $1,217.7
 28.4 % $1,499
 25.6 % $1,363
 28.6 %
Analytical Instruments 1,052.0
 22.1 % 759.3
 17.7 % 1,257
 21.5 % 1,052
 22.1 %
Specialty Diagnostics 866.4
 18.2 % 854.6
 19.9 % 947
 16.2 % 866
 18.2 %
Laboratory Products and Services 1,699.0
 35.7 % 1,648.8
 38.4 % 2,413
 41.2 % 1,699
 35.7 %
Eliminations (215.9) (4.6)% (185.6) (4.4)% (263) (4.5)% (215) (4.6)%
                
 $4,765.0
 100 % $4,294.8
 100 % $5,853
 100 % $4,765
 100 %
Sales in the first quarter of 20172018 were $4.77$5.85 billion, an increase of $470 million$1.09 billion from 2016.2017. Sales increased $346$565 million due to acquisitions. The unfavorablefavorable effects of currency translation resulted in a decreasean increase in revenues of $56$209 million in the first quarter of 2017.2018. Aside from the effects of acquisitions and currency translation, revenues increased $181$314 million (4%(7%) primarily due to increased demand in the fiscal quarter compared to the 20162017 quarter. Sales to customers in each of the company's primary end markets grew. Demand from customers in pharmaceutical and biotech industries was particularly strong. Sales growth was modestmoderate in North America, moderatestrong in Europe and particularly strong in Asia. Based on the weakening of the currency exchange rates against the U.S. dollar that occurred in 2016 and the first three months of 2017, the company currently expects that there will be a continued adverse effect on reported amounts of revenue and operating income in 2017 as a result of the stronger U.S. dollar.
In the first quarter of 2017,2018, total company operating income and operating income margin were $622$786 million and 13.1%13.4%, respectively, compared with $518$620 million and 12.1%13.0%, respectively, in 2016.2017. The increase in operating income was primarily due to profit on higher sales in local currencies and, to a lesser extent, the effect of acquisitions and productivity improvements, net of inflationary cost increases, and acquisitions offset in part by an increase in amortization of acquisition-related intangible assets, due to recent acquisitions, and strategic growth investments. The company’s references to strategic growth investments generally refer to targeted spending for enhancing commercial capabilities, including expansion of geographic sales reach and e-commerce platforms, marketing initiatives, focused research projects and other expenditures to enhance the customer experience. The company’s references throughout this discussion to productivity improvements generally refer to improved cost efficiencies from its Practical Process Improvement (PPI) business system, reduced costs resulting from global sourcing initiatives, a lower cost structure following restructuring actions, including headcount reductions and consolidation of facilities, and low cost region manufacturing.
The company recorded a benefit from$55 million provision for income taxes in the first quarter of 2018. In the first quarter of 2018, the company recorded a net tax provision of $21 million to adjust the estimated initial impacts of U.S. tax reform recorded in 2017, asconsisting of an incremental provision of $70 million offset in part by a result$49 million reduction of a $65 million favorable adjustment to deferred tax balances due to extension of a tax holiday agreement in Singapore and $24 million of benefit associated with new required accounting forrelated unrecognized tax benefits from equity awards, as discussedestablished in Note 1.2017. The adjustment was required based on new U.S. Treasury guidance released in the first quarter of 2018. The company expects its effective tax rate for all of 20172018 will be less than 3%between 6% and 9% based on currently forecasted rates of profitability in the countries in which the company conducts business and expected generation of foreign tax credits. Due primarily to the non-deductibility of intangible asset amortization for tax purposes, the company’s cash payments for income taxes are higher than its income tax expense for financial reporting purposes and are expected to total $600$525 to $625$575 million in 2017.2018.
The company's effective tax rate was 4.9%company recorded a $48 million benefit from income taxes in the first quarter of 2016. In 2016, the company implemented tax planning initiatives related to non-U.S. subsidiaries. These non-U.S. subsidiaries incurred foreign tax obligations, and made cash and deemed distributions to the company’s U.S. operations which resulted in no net tax cost. As2017 as a result of these distributions, the company benefitted from U.S. foreigna $65 million favorable adjustment to deferred tax creditsbalances due to extension of $46 million, offseta tax holiday agreement in part by additional U.S. taxes of $16 million on the related foreign income (which reduced the benefit from the foreign rate differential in 2016) for a net benefit of $30 million. The foreign tax credits are the result of foreign earnings remitted or deemed remitted to the U.S. during the reporting year and the U.S. treatment of taxes paid in the foreign jurisdictions in the years those profits were originally earned.Singapore. The effective rate in both periods was also affected by relatively significant earnings in lower tax jurisdictions.
Income from continuing operationsNet income increased to $579 million in the first quarter of 2018 from $551 million in the first quarter of 2017, from $402 million in the first quarter of 2016primarily due to the increase in operating income in the 20172018 period (discussed above) and an increase in the income tax benefit in the 2017 period (discussed above). These increases were offset in part by an increase inhigher income taxes (discussed above) and, to a lesser extent, higher interest expense due to an increasesincrease in outstanding debt.
During the first three months of 2018, the company’s cash flow from operations totaled $78 million compared with $361 million for 2017. The decrease primarily resulted from higher investment in working capital in 2018, offset in part by higher income before amortization and depreciation in the 2018 period.
As of March 31, 2018, the company’s short-term debt totaled $2.81 billion including $1.17 billion of commercial paper obligations and $1.64 billion of senior notes due within the next twelve months. The company has a revolving credit facility with a bank group that provides up to $2.50 billion of unsecured multi-currency revolving credit. If the company borrows under

3031



THERMO FISHER SCIENTIFIC INC.
MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
AND RESULTS OF OPERATIONS
Overview of Results of Operations and Liquidity (continued)

During the first three months of 2017, the company’s cash flow from operations totaled $362 million compared with $335 million for 2016. The increase primarily resulted from higher earnings before amortization and depreciation in 2017.
As of April 1, 2017, the company’s short-term debt totaled $1.88 billion, including $350 million due within the next twelve months under a 3-year term loan agreement and $1.53 billion of commercial paper obligations. The company has a revolving credit facility with a bank group that provides up to $2.50 billion of unsecured multi-currency revolving credit. If the company borrows under this facility, it intends to leave undrawn an amount equivalent to outstanding commercial paper to provide a source of funds in the event that commercial paper markets are not available. As of April 1, 2017,March 31, 2018, no borrowings were outstanding under the company’s revolving credit facility, although available capacity was reduced by approximately $73$75 million as a result of outstanding letters of credit.
The company believes that its existing cash and cash equivalents of $713$950 million as of April 1, 2017March 31, 2018 and its future cash flow from operations together with available borrowing capacity under its revolving credit agreement will be sufficient to meet the cash requirements of its existing businesses for the foreseeable future, including at least the next 24 months.
Critical Accounting Policies and Estimates
The company’s discussion and analysis of its financial condition and results of operations is based upon its financial statements, which have been prepared in accordance with accounting principles generally accepted in the United States of America. The preparation of these financial statements requires management to make estimates and assumptions that affect the reported amounts of assets, liabilities, revenue and expenses and related disclosure of contingent liabilities. On an on-going basis, management evaluates its estimates, including those related to bad debts, inventories, business combinations, intangible assets and goodwill, sales returns, income taxes, contingencies and litigation, and pension costs. Management believes the most complex and sensitive judgments, because of their significance to the consolidated financial statements, result primarily from the need to make estimates about the effects of matters that are inherently uncertain. Management bases its estimates on historical experience, current market and economic conditions and other assumptions that management believes are reasonable. The results of these estimates form the basis for judgments about the carrying value of assets and liabilities where the values are not readily apparent from other sources. Actual results may differ from these estimates under different assumptions or conditions. Management’s Discussion and Analysis and Note 1 to the Consolidated Financial Statements of the company’s Form 10-K for 2016,2017, describe the significant accounting estimates and policies used in preparation of the consolidated financial statements. ThereWhile there have been no significant changes in the company's critical accounting policies during the first three months of 2017.2018, as described in Note 1, the company changed the manner in which it accounts for revenue from contracts with customers under guidance that became effective January 1, 2018.
Results of Operations
First Quarter 20172018 Compared With First Quarter 20162017
 Three Months Ended         Three Months Ended        
(In millions) April 1,
2017

 April 2,
2016

 
Total
Change

 
Currency
Translation

 
Acquisitions/
Divestitures

 Operations
 March 31,
2018

 April 1,
2017

 
Total
Change

 
Currency
Translation

 
Acquisitions/
Divestitures

 Operations
                        
Revenues                        
Life Sciences Solutions $1,363.5
 $1,217.7
 $145.8
 $(17.1) $78.9
 $84.0
 $1,499
 $1,363
 $136
 $62
 $
 $74
Analytical Instruments 1,052.0
 759.3
 292.7
 (12.8) 266.1
 39.4
 1,257
 1,052
 205
 54
 12
 139
Specialty Diagnostics 866.4
 854.6
 11.8
 (9.7) 0.8
 20.7
 947
 866
 81
 38
 3
 40
Laboratory Products and Services 1,699.0
 1,648.8
 50.2
 (21.8) 3.2
 68.8
 2,413
 1,699
 714
 62
 554
 98
Eliminations (215.9) (185.6) (30.3) 5.1
 (3.5) (31.9) (263) (215) (48) (7) (4) (37)
                        
Consolidated Revenues $4,765.0
 $4,294.8
 $470.2
 $(56.3) $345.5
 $181.0
 $5,853
 $4,765
 $1,088
 $209
 $565
 $314
Sales in the first quarter of 20172018 were $4.77$5.85 billion, an increase of $470 million$1.09 billion from the first quarter of 2016.2017. Sales increased $346$565 million due to acquisitions. The unfavorablefavorable effects of currency translation resulted in a decreasean increase in revenues of $56$209 million in 2017.2018. Aside from the effects of acquisitions/divestitures and currency translation, revenues increased $181$314 million (4%(7%) primarily due to increased demand in the fiscal quarter compared to the 20162017 quarter. Sales to customers in each of the company's primary end markets grew. Demand from customers in pharmaceutical and biotech industries was particularly strong. Sales growth was modestmoderate in North America, moderatestrong in Europe and particularly strong in Asia.
In the first quarter of 2018, total company operating income and operating income margin were $786 million and 13.4%, respectively, compared with $620 million and 13.0%, respectively, in 2017. The increase in operating income was primarily due to profit on higher sales in local currencies and, to a lesser extent, the effect of acquisitions and productivity improvements, net of inflationary cost increases, offset in part by an increase in amortization of acquisition-related intangible assets, due to recent acquisitions, and strategic growth investments.

3132



THERMO FISHER SCIENTIFIC INC.
MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
AND RESULTS OF OPERATIONS
Results of Operations (continued)

In the first quarter of 2017, total2018, the company operating incomerecorded restructuring and operating income margin were $622 million and 13.1%, respectively, compared with $518 million and 12.1%, respectively, in 2016. The increase in operating income was primarily due to profit on higher sales in local currencies, productivity improvements,other costs, net, of inflationary$56 million, including $3 million of charges to cost increases,of revenues primarily for the sale of inventories revalued at the date of acquisition. The company recorded $8 million of charges to selling, general and acquisitions offsetadministrative expenses, primarily for third-party transaction/integration costs related to the acquisition of Patheon. The company recorded $35 million of cash restructuring costs, including severance and abandoned facilities costs associated with the closure and consolidation of facilities in part by an increase in amortizationthe U.S. and Europe. The company also recorded $10 million of acquisition-related intangible assets, due to recent acquisitions,other charges, net, principally for litigation-related matters and strategic growth investments.hurricane response costs (see Note 13).
In the first quarter of 2017, the company recorded restructuring and other costs, net, of $86 million, including $31 million of charges to cost of revenues primarily for the sale of inventories revalued at the date of acquisition and $32$31 million of charges to selling, general and administrative expenses, primarily for changes in estimates of acquisition contingent consideration. In addition, the company recorded $18 million of cash restructuring costs, primarily to achieve acquisition synergies, including severance and abandoned facilities costs associated with the closure and consolidation of facilities in the U.S. The company’s other businesses incurred costs for continued headcount reductions and facility consolidations in an effort to streamline operations including severance at several businesses and abandoned facility expenses at businesses that have been or are being consolidated in the U.S., Europe and Asia. The company also recorded $5 million of other costs,charges, net, principally litigation charges (see Note 13).
In the first quarter of 2016, the company recorded restructuring and other costs, net, of $90 million, including $11 million of charges to cost of revenues for the sale of inventories revalued at the date of acquisition and to conform the accounting policies of Affymetrix with the company's accounting policies; and $29 million of charges to selling, general and administrative expenses primarily for third-party transaction costs related to the acquisition of Affymetrix. In addition, the company recorded $67 million of cash restructuring costs, primarily to achieve acquisition synergies, including severance and abandoned facilities costs associated with the closure and consolidation of facilities in the U.S. The company’s other businesses incurred costs for continued headcount reductions and facility consolidations in an effort to streamline operations including severance at several businesses and abandoned facility expenses at businesses that have been or are being consolidated in the U.S., Europe and Asia. These costs were partially offset by gains on the settlement of litigation and sale of real estate.litigation-related matters.
As of May 5, 2017,4, 2018, the company has identified restructuring actions that will result in additional charges of approximately $95$105 million in 20172018 and 2018,2019, and expects to identify additional actions during 20172018 which will be recorded when specified criteria are met, such as communication of benefit arrangements and abandonment of leased facilities.
Segment Results
The company’s management evaluates segment operating performance using operating income before certain charges/credits to cost of revenues and selling, general and administrative expenses, principally associated with acquisition-related activities; restructuring and other costs/income including costs arising from facility consolidations such as severance and abandoned lease expense and gains and losses from the sale of real estate and product lines; and amortization of acquisition-related intangible assets. The company uses this measure because it helps management understand and evaluate the segments’ core operating results and facilitate comparison of performance for determining compensation (Note 3)4). Accordingly, the following segment data is reported on this basis.

3233



THERMO FISHER SCIENTIFIC INC.
MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
AND RESULTS OF OPERATIONS
Results of Operations (continued)

 Three Months Ended Three Months Ended
 April 1,
 April 2,
   March 31,
 April 1,
  
(Dollars in millions) 2017
 2016
 Change
 2018
 2017
 Change
            
Revenues            
Life Sciences Solutions $1,363.5
 $1,217.7
 12 % $1,499
 $1,363
 10%
Analytical Instruments 1,052.0
 759.3
 39 % 1,257
 1,052
 19%
Specialty Diagnostics 866.4
 854.6
 1 % 947
 866
 9%
Laboratory Products and Services 1,699.0
 1,648.8
 3 % 2,413
 1,699
 42%
Eliminations (215.9) (185.6) 16 % (263) (215) 22%
            
Consolidated Revenues $4,765.0
 $4,294.8
 11 % $5,853
 $4,765
 23%
            
Segment Income            
Life Sciences Solutions $433.9
 $351.3
 24 % $517
 $433
 19%
Analytical Instruments 191.8
 111.7
 72 % 246
 192
 28%
Specialty Diagnostics 233.9
 230.1
 2 % 243
 233
 4%
Laboratory Products and Services 216.2
 236.9
 (9)% 280
 216
 30%
            
Subtotal Reportable Segments 1,075.8
 930.0
 16 % 1,286
 1,074
 20%
            
Cost of Revenues Charges (30.9) (10.6)   (3) (31)  
Selling, General and Administrative Charges, Net (31.5) (28.9)   (8) (31)  
Restructuring and Other Costs, Net (23.5) (50.6)   (45) (24)  
Amortization of Acquisition-related Intangible Assets (367.5) (322.0)   (444) (368)  
            
Consolidated Operating Income $622.4
 $517.9
 20 % $786
 $620
 27%
            
Reportable Segments Operating Income Margin 22.6% 21.7%   22.0% 22.5%  
            
Consolidated Operating Income Margin 13.1% 12.1%   13.4% 13.0%  
Income from the company’s reportable segments increased 16%20% to $1.08$1.29 billion in the first quarter of 20172018 due primarily to profit on higher sales in local currencies and, to a lesser extent, the effect of acquisitions, favorable foreign currency exchange and productivity improvements, net of inflationary cost increases, and acquisitions offset in part by strategic growth investments.
Life Sciences Solutions
 Three Months Ended Three Months Ended
 April 1,
 April 2,
   March 31,
 April 1,
  
(Dollars in millions) 2017
 2016
 Change
 2018
 2017
 Change
            
Revenues $1,363.5
 $1,217.7
 12% $1,499
 $1,363
 10%
            
Operating Income Margin 31.8% 28.9% 2.9 pt
 34.5% 31.8% 2.7 pt
Sales in the Life Sciences Solutions segment increased $146$136 million to $1.36$1.50 billion in the first quarter of 2017.2018. Sales increased $84$74 million (7%(5%) due to higher revenues at existing businesses and $79 million due to an acquisition, offset in part by a decrease of $17$62 million due to the unfavorablefavorable effects of currency translation. The increase in revenue at existing businesses was primarily due to increased demand for bioprocess production products as well as biosciences products and to a lesser extent, genetic sciencesbioprocess production products.
Operating income margin was 34.5% in the first quarter of 2018 compared to 31.8% in the first quarter of 2017 compared to 28.9% in the first quarter of 2016.2017. The increase resulted primarily from productivity improvements, net of inflationary cost increases, profit on higher sales in local currencies and to a lesser extent, price increases.favorable foreign currency exchange. These increases were offset in part by acquisition dilution and, to a lesser extent, strategic growth investments.unfavorable sales mix.

3334



THERMO FISHER SCIENTIFIC INC.
MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
AND RESULTS OF OPERATIONS
Results of Operations (continued)

Analytical Instruments
 Three Months Ended Three Months Ended
 April 1,
 April 2,
   March 31,
 April 1,
  
(Dollars in millions) 2017
 2016
 Change
 2018
 2017
 Change
            
Revenues $1,052.0
 $759.3
 39% $1,257
 $1,052
 19%
            
Operating Income Margin 18.2% 14.7% 3.5 pt
 19.6% 18.2% 1.4 pt
Sales in the Analytical Instruments segment increased $293$205 million to $1.05$1.26 billion in the first quarter of 2017.2018. Sales increased $266$139 million due to acquisitions and $39 million (5%(13%) due to higher revenues at existing businesses.businesses, $54 million due to the favorable effects of currency translation and $12 million due to acquisitions. The increase in revenue at existing businesses was primarily due to increased demand at each of the segment's principal businesses, particularly for products sold by the segment's electron microscopy business and chromatography and mass spectrometry business.
Operating income margin was 19.6% in the first quarter of 2018 compared to 18.2% in the first quarter of 2017 compared to 14.7% in the first quarter of 2016.2017. The increase resulted primarily from profit on higher sales in local currencies and, to a lesser extent, productivity improvements, net of inflationary cost increases, and the effect of acquisitions, offset in part by strategic growth investments.investments and, to a lesser extent, unfavorable foreign currency exchange.
Specialty Diagnostics
 Three Months Ended Three Months Ended
 April 1,
 April 2,
   March 31,
 April 1,
  
(Dollars in millions) 2017
 2016
 Change
 2018
 2017
 Change
            
Revenues $866.4
 $854.6
 1% $947
 $866
 9%
            
Operating Income Margin 27.0% 26.9% 0.1 pt
 25.6% 26.9% -1.3 pt
Sales in the Specialty Diagnostics segment increased $12$81 million to $866$947 million in the first quarter of 2017.2018. Sales increased $21$40 million (2%(5%) due to higher revenues at existing businesses, offset in part by a decrease of $10$38 million due to the unfavorablefavorable effects of currency translation.translation and $3 million due to an acquisition. The increase in revenue at existing businesses was due to increased broad based higher demand with particular strength in sales of clinical diagnostics products and products sold through the segment’s healthcare market channel.channel and, to a lesser extent, clinical diagnostic products.
Operating income margin was 27.0%25.6% in the first quarter of 20172018 and 26.9% in the first quarter of 2016.2017. The increasedecrease resulted primarily from productivity improvements, net of inflationary cost increasesunfavorable sales mix and to a lesser extent,strategic growth investments, offset in part by profit on higher sales in local currencies and favorable foreign currency exchange, offset in part by strategic growth investments.exchange.
Laboratory Products and Services
 Three Months Ended Three Months Ended
 April 1,
 April 2,
   March 31,
 April 1,
  
(Dollars in millions) 2017
 2016
 Change
 2018
 2017
 Change
            
Revenues $1,699.0
 $1,648.8
 3% $2,413
 $1,699
 42%
            
Operating Income Margin 12.7% 14.4% -1.7 pt
 11.6% 12.7% -1.1 pt
Sales in the Laboratory Products and Services segment increased $50$714 million to $1.70$2.41 billion in the first quarter of 2017.2018. Sales increased $69$554 million (4%due to an acquisition, $98 million (6%) due to higher revenues at existing businesses and $3 million due to an acquisition. These increases were offset in part by $22$62 million due to the unfavorablefavorable effects of currency translation. The increase in revenue at existing businesses was primarily due to increased demand for products sold through the segment's channel business as well as laboratory equipment and, consumables.
Operating income margin was 12.7% in the first quarter of 2017 and 14.4% in the first quarter of 2016. The decrease was primarily due to unfavorable sales mix and strategic growth investments, offset in part by profit on higher sales in local currencies and productivity improvements, net of inflationary cost increases.a lesser extent, its clinical trials business.

3435



THERMO FISHER SCIENTIFIC INC.
MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
AND RESULTS OF OPERATIONS
Results of Operations (continued)

Operating income margin was 11.6% in the first quarter of 2018 and 12.7% in the first quarter of 2017. The decrease was primarily due to unfavorable sales mix and, to a lesser extent, strategic investments offset in part by profit on higher sales in local currencies.
Other Expense, Net
The company reported other expense, net, of $120$152 million and $95$117 million in the first quarter of 20172018 and 2016,2017, respectively (Note 4)5). Interest expense increased $29$28 million, primarily due to an increasesincrease in outstanding debt to fund acquisitions. In 2017, other items, net includes net gains on investments of $6 million, offset in part by a $3 million loss on the early extinguishment of debt.
Provision for Income Taxes
The company recorded a benefit from$55 million provision for income taxes in the first quarter of 2018. In the first quarter of 2018, the company recorded a net tax provision of $21 million to adjust the estimated initial impacts of U.S. tax reform recorded in 2017, asconsisting of an incremental provision of $70 million offset in part by a result$49 million reduction of a $65 million favorable adjustment to deferred tax balances due to extension of a tax holiday agreement in Singapore and $24 million of benefit associated with new required accounting forrelated unrecognized tax benefits from equity awards, as discussedestablished in Note 1.2017. The adjustment was required based on new U.S. Treasury guidance released in the first quarter of 2018. The company expects its effective tax rate for all of 20172018 will be less than 3%between 6% and 9% based on currently forecasted rates of profitability in the countries in which the company conducts business and expected generation of foreign tax credits. Due primarily to the non-deductibility of intangible asset amortization for tax purposes, the company’s cash payments for income taxes are higher than its income tax expense for financial reporting purposes and are expected to total $600$525 to $625$575 million in 2017.2018.
The company's effective tax rate was 4.9%company recorded a $48 million benefit from income taxes in the first quarter of 2016. In 2016, the company implemented tax planning initiatives related to non-U.S. subsidiaries. These non-U.S. subsidiaries incurred foreign tax obligations, and made cash and deemed distributions to the company’s U.S. operations which resulted in no net tax cost. As2017 as a result of these distributions, the company benefitted from U.S. foreigna $65 million favorable adjustment to deferred tax creditsbalances due to extension of $46 million, offseta tax holiday agreement in part by additional U.S. taxes of $16 million on the related foreign income (which reduced the benefit from the foreign rate differential in 2016) for a net benefit of $30 million. The foreign tax credits are the result of foreign earnings remitted or deemed remitted to the U.S. during the reporting year and the U.S. treatment of taxes paid in the foreign jurisdictions in the years those profits were originally earned.Singapore. The effective rate in both periods was also affected by relatively significant earnings in lower tax jurisdictions.
The company has operations and a taxable presence in approximately 50 countries outside the U.S. AllSome of these countries except one have a lower tax rate than the U.S. The countries in which the company has a material presence that have significantly lower tax rates than the U.S. include Germany, the Netherlands, Singapore, Sweden, Switzerland and the United Kingdom. The company’s ability to obtain a benefit from lower tax rates outside the U.S. is dependent on its relative levels of income in countries outside the U.S. and on the statutory tax rates in those countries. Based on the dispersion of the company’s non-U.S. income tax provision among many countries, the company believes that a change in the statutory tax rate in any individual country is not likely to materially affect the company’s income tax provision or net income, aside from any resulting one-time adjustment to the company’s deferred tax balances to reflect a new rate.
Recent Accounting Pronouncements
A description of recently issued accounting standards is included under the heading "Recent Accounting PronouncementsPronouncements" in Note 1.
Contingent Liabilities
The company is contingently liable with respect to certain legal proceedings and related matters. An unfavorable outcome that differs materially from current accrual estimates, if any, for one or more of the matters described under the headings "Product Liability, Workers Compensation and Other Personal Injury Matters," "Intellectual Property Matters" and "Commercial Matters" in Note 9 could have a material adverse effect on the company’s financial position as well as its results of operations and cash flows.
Liquidity and Capital Resources
Consolidated working capital was $1.95$2.52 billion at April 1, 2017,March 31, 2018, compared with $2.16$2.37 billion at December 31, 2016.2017. Included in working capital were cash and cash equivalents of $713$950 million at April 1, 2017March 31, 2018 and $786 million$1.34 billion at December 31, 2016. The decrease2017.
First Three Months of 2018
Cash provided by operating activities was $78 million during the first three months of 2018. Cash provided by income was offset in part by investments in working capital iscapital. Increases in accounts receivable and inventories used cash of $71 million and $124 million, respectively, primarily to support growth in sales in local currencies. An increase in other assets used cash of $192 million primarily due to anthe timing of income tax refunds and customer billings. Other liabilities decreased by $520 million primarily due to the timing of payments for incentive compensation and income taxes. Cash payments for income taxes increased to $331 million during the first three months of 2018, compared with $215 million in the first three months of 2017. The company made cash contributions to its pension and postretirement benefit plans totaling $24 million during the first three months of 2018. Payments for restructuring actions, principally severance costs and lease and other expenses of real estate consolidation, used cash of $23 million during the first three months of 2018.

36



THERMO FISHER SCIENTIFIC INC.
MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
AND RESULTS OF OPERATIONS
Liquidity and Capital Resources (continued)

During the first three months of 2018, the company’s investing activities used $179 million of cash. Acquisitions used cash of $57 million. The company’s investing activities also included the purchase of $118 million of property, plant and equipment.
The company’s financing activities used $342 million of cash during the first three months of 2018. Repayment of senior notes used cash of $453 million. A net increase in commercial paper obligations.obligations provided cash of $182 million. The company’s financing activities also included the payment of $60 million in cash dividends, offset in part by $39 million of net proceeds from employee stock option exercises. On July 7, 2016, the Board of Directors authorized the repurchase of up to $1.50 billion of the company’s common stock. At May 4, 2018, $500 million was available for future repurchases of the company’s common stock under this authorization. In May 2018, the company issued additional commercial paper obligations and used the proceeds and cash on hand to repay all of the $900 million principal balance of the 2.40% Senior Notes due 2019.
The company's commitments for purchases of property, plant and equipment, contractual obligations and other commercial commitments did not change materially between December 31, 2017 and March 31, 2018, except for changes in debt (discussed above). The company expects that for all of 2018, expenditures for property, plant and equipment, net of disposals, will approximate $700 to $730 million.
As of March 31, 2018, the company’s short-term debt totaled $2.81 billion including $1.17 billion of commercial paper obligations and $1.64 billion of senior notes due within the next twelve months. The company has a revolving credit facility with a bank group that provides up to $2.50 billion of unsecured multi-currency revolving credit. If the company borrows under this facility, it intends to leave undrawn an amount equivalent to outstanding commercial paper to provide a source of funds in the event that commercial paper markets are not available. As of March 31, 2018, no borrowings were outstanding under the company’s revolving credit facility, although available capacity was reduced by approximately $75 million as a result of outstanding letters of credit.
Approximately half of the company’s cash balances and cash flows from operations are from outside the U.S. The company uses its non-U.S. cash for needs outside of the U.S. including acquisitions and repayment of acquisition-related intercompany debt to the U.S. In addition, the company also transfers cash to the U.S. using non-taxable returns of capital as well as dividends where the related U.S. dividend received deduction or foreign tax credit equals any tax cost arising from the dividends. As a result of using such means of transferring cash to the U.S., the company does not expect any material adverse liquidity effects from its significant non-U.S. cash balances for the foreseeable future.
The company believes that its existing cash and cash equivalents of $950 million as of March 31, 2018 and its future cash flow from operations together with available borrowing capacity under its revolving credit agreement will be sufficient to meet the cash requirements of its existing businesses for the foreseeable future, including at least the next 24 months.
First Three Months of 2017
Cash provided by operating activities was $362$361 million during the first three months of 2017. An increase in inventories used cash of $105 million primarily to support growth in sales in local currencies. An increase in other assets used cash of $134 million primarily due to the timing of payments. A decrease in otherOther liabilities used cash ofdecreased by $303 million primarily due to the timing of payments for income taxes and incentive compensation and income taxes.compensation. Cash payments for income taxes decreased tototaled $215 million during the first three months of 2017, compared with $223 million in the first three months of 2016.million. The company made cash

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MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
AND RESULTS OF OPERATIONS
Liquidity and Capital Resources (continued)

contributions to its pension and postretirement benefit plans totaling $173 million during the first three months of 2017. Payments for restructuring actions, principally severance costs and lease and other expenses of real estate consolidation, used cash of $32 million during the first three months of 2017.
During the first three months of 2017, the company’s investing activities used $382 million of cash. Acquisitions used cash of $301 million. The company’s investing activities also included the purchase of $93 million of property, plant and equipment.
The company’s financing activities used $119 million of cash during the first three months of 2017. Issuance of senior notesdebt provided cash of $519 million and an increase in commercial paper obligations provided cash of $566 million. Repayment of senior notes and the term loandebt used cash of $703 million. The company’s financing activities also included the repurchase of $500 million of the company’scompany's common stock and the payment of $59 million in cash dividends, offset in part by $58 million of net proceeds from employee stock option exercises. On July 7, 2016, the Board of Directors authorized the repurchase of up to $1.50 billion of the company’s common stock. At May 5, 2017, $500 million was available for future repurchases of the company’s common stock under this authorization.
The company's commitments for purchases of property, plant and equipment, contractual obligations and other commercial commitments did not change materially between December 31, 2016 and April 1, 2017. The company expects that for all of 2017, expenditures for property, plant and equipment, net of disposals, will approximate $500 million.
As of April 1, 2017, the company’s short-term debt totaled $1.88 billion, including $350 million due within the next twelve months under a 3-year term loan agreement and $1.53 billion of commercial paper obligations. The company has a revolving credit facility with a bank group that provides up to $2.50 billion of unsecured multi-currency revolving credit. If the company borrows under this facility, it intends to leave undrawn an amount equivalent to outstanding commercial paper to provide a source of funds in the event that commercial paper markets are not available. As of April 1, 2017, no borrowings were outstanding under the company’s revolving credit facility, although available capacity was reduced by approximately $73 million as a result of outstanding letters of credit.
Approximately half of the company’s cash balances and cash flows from operations are from outside the U.S. The company uses its non-U.S. cash for needs outside of the U.S. including acquisitions and repayment of acquisition-related intercompany debt to the U.S. In addition, the company also transfers cash to the U.S. using non-taxable returns of capital as well as dividends where the related U.S. foreign tax credit equals or exceeds any tax cost arising from the dividends. As a result of using such means of transferring cash to the U.S., the company does not expect any material adverse liquidity effects from its significant non-U.S. cash balances for the foreseeable future.
The company believes that its existing cash and cash equivalents of $713 million as of April 1, 2017 and its future cash flow from operations together with available borrowing capacity under its revolving credit agreement will be sufficient to meet the cash requirements of its existing businesses for the foreseeable future, including at least the next 24 months.
First Three Months of 2016
Cash provided by operating activities was $335 million during the first three months of 2016. Increases in accounts receivable and inventories used cash of $30 million and $56 million, respectively, primarily to support growth in sales in local currencies. An increase in other assets used cash of $39 million primarily due to the timing of tax payments. Other liabilities decreased by $335 million primarily due to the timing of payments for incentive compensation, income taxes and interest. Cash payments for income taxes totaled $223 million. The company made cash contributions to its pension and postretirement benefit plans totaling $22 million during the first three months of 2016. Payments for restructuring actions, principally severance costs and lease and other expenses of real estate consolidation, used cash of $22 million during the first three months of 2016.
During the first three months of 2016, the company’s investing activities used $1.14 billion of cash. Acquisitions used cash of $1.03 billion. The company’s investing activities also included the purchase of $115 million of property, plant and equipment.
The company’s financing activities provided $1.14 billion of cash during the first three months of 2016. Issuance of debt provided cash of $1.00 billion and an increase in commercial paper obligations provided cash of $1.17 billion. The company’s financing activities also included the repurchase of $1.00 billion of the company's common stock and the payment of $60 million in cash dividends, offset in part by $32 million of net proceeds from employee stock option exercises.


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Item 3.Quantitative and Qualitative Disclosures About Market Risk
The company's exposure to market risk from changes in interest rates and currency exchange rates has not changed materially from its exposure at year-end 2016.2017.

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Item 4.Controls and Procedures
Management’s Evaluation of Disclosure Controls and Procedures
The company’s management, with the participation of the company’s chief executive officer and chief financial officer, evaluated the effectiveness of the company’s disclosure controls and procedures as of April 1, 2017.March 31, 2018. The term “disclosure"disclosure controls and procedures," as defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act, means controls and other procedures of a company that are designed to ensure that information required to be disclosed by a company in the reports that it files or submits under the Exchange Act is recorded, processed, summarized and reported, within the time periods specified in the SEC’s rules and forms. Disclosure controls and procedures include, without limitation, controls and procedures designed to ensure that information required to be disclosed by a company in the reports that it files or submits under the Exchange Act is accumulated and communicated to the company’s management, including its principal executive and principal financial officers, as appropriate to allow timely decisions regarding required disclosure. Management recognizes that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving their objectives and management necessarily applies its judgment in evaluating the cost-benefit relationship of possible controls and procedures. Based on the evaluation of the company’s disclosure controls and procedures as of April 1, 2017,March 31, 2018, the company’s chief executive officer and chief financial officer concluded that, as of such date, the company’s disclosure controls and procedures were effective at the reasonable assurance level.
Changes in Internal Control over Financial Reporting
There have been no changes in the company’s internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) during the fiscal quarter ended April 1, 2017,March 31, 2018, that have materially affected or are reasonably likely to materially affect the company’s internal control over financial reporting.

PART IIOTHER INFORMATION
Item 1.Legal Proceedings
There are various lawsuits and claims against the company involving product liability, intellectual property, employment and commercial issues. See “Note"Note 9 to our Consolidated Financial Statements – Commitments and Contingencies."

Item 1A.Risk Factors
Set forth below are the risks that we believe are material to our investors. This section contains forward-looking statements. You should refer to the explanation of the qualifications and limitations on forward-looking statements beginning on page 2930.
We must develop new products, adapt to rapid and significant technological change and respond to introductions of new products by competitors to remain competitive.Our growth strategy includes significant investment in and expenditures for product development. We sell our products in several industries that are characterized by rapid and significant technological changes, frequent new product and service introductions and enhancements and evolving industry standards. Competitive factors include technological innovation, price, service and delivery, breadth of product line, customer support, e-business capabilities and the ability to meet the special requirements of customers. Our competitors may adapt more quickly to new technologies and changes in customers’ requirements than we can. Without the timely introduction of new products, services and enhancements, our products and services will likely become technologically obsolete over time, in which case our revenue and operating results would suffer.
Many of our existing products and those under development are technologically innovative and require significant planning, design, development and testing at the technological, product and manufacturing-process levels. Our customers use many of our products to develop, test and manufacture their own products. As a result, we must anticipate industry trends and develop products in advance of the commercialization of our customers’ products. If we fail to adequately predict our

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Risk Factors (continued)


customers’ needs and future activities, we may invest heavily in research and development of products and services that do not lead to significant revenue.

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Risk Factors (continued)


It may be difficult for us to implement our strategies for improving internal growthgrowth. Some of the markets in which we compete have been flat or declining over the past several years. To address this issue, we are pursuing a number of strategies to improve our internal growth, including:
strengthening our presence in selected geographic markets;
allocating research and development funding to products with higher growth prospects;
developing new applications for our technologies;
expanding our service offerings;
continuing key customer initiatives;
combining sales and marketing operations in appropriate markets to compete more effectively;
finding new markets for our products; and
continuing the development of commercial tools and infrastructure to increase and support cross-selling opportunities of products and services to take advantage of our depth in product offerings.
We may not be able to successfully implement these strategies, and these strategies may not result in the expected growth of our business.
Our business is affected by general economic conditions and related uncertainties affecting markets in which we operate.Our business is affected by general economic conditions, both inside and outside the U.S. If the global economy and financial markets, or economic conditions in Europe, the U.S. or other key markets, are unstable, it could adversely affect the business, results of operations and financial condition of the company and its customers, distributors, and suppliers, having the effect of
reducing demand for some of our products;
increasing the rate of order cancellations or delays;
increasing the risk of excess and obsolete inventories;
increasing pressure on the prices for our products and services; and
creating longer sales cycles and greater difficulty in collecting sales proceeds.
Demand for some of our products depends on capital spending policies of our customers and on government funding policies.Our customers include pharmaceutical and chemical companies, laboratories, universities, healthcare providers, government agencies and public and private research institutions. Many factors, including public policy spending priorities, available resources and product and economic cycles, have a significant effect on the capital spending policies of these entities.
Spending by some of these customers fluctuates based on budget allocations and the timely passage of the annual federal budget. An impasse in federal government budget decisions could lead to substantial delays or reductions in federal spending.
As a multinational corporation, we are exposed to fluctuations in currency exchange rates, which could adversely affect our cash flows and results of operations.International markets contribute a substantial portion of our revenues, and we intend to continue expanding our presence in these regions. The exposure to fluctuations in currency exchange rates takes on different forms. International revenues and costs are subject to the risk that fluctuations in exchange rates could adversely affect our reported revenues and profitability when translated into U.S. dollars for financial reporting purposes. These fluctuations could also adversely affect the demand for products and services provided by us. As a multinational corporation, our businesses occasionally invoice third-party customers in currencies other than the one in which they primarily do business (the “functional currency”"functional currency"). Movements in the invoiced currency relative to the functional currency could adversely impact our cash flows and our results of operations. ShouldAs our international sales grow, exposure to fluctuations in currency exchange rates could have a larger effect on our financial results. In the first three months of 2017,2018, currency translation had an unfavorablea favorable effect of $56$209 million on revenues due to the strengtheningweakening of the U.S. dollar relative to other currencies in which the company sells products and services.
Significant developments stemming from the recent U.S. presidential electionadministration or the U.K.’s referendum on membership in the EU could have an adverse effect on us.The new U.S. administration has called for substantial changes to trade agreements, such as the North American Free Trade Agreement (NAFTA), and has raised the possibility ofis imposing significant increases on tariffs on goods imported into the United States, particularly from China and Mexico. The new administration has also indicated an intention to request Congress

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Risk Factors (continued)


to make significant changes, replacement or elimination of the Patient Protection and Affordable Care Act, and government negotiation/regulation of drug prices paid by government programs. Changes in U.S.

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Risk Factors (continued)


social, political, regulatory and economic conditions or laws and policies governing the health care system and drug prices, foreign trade, manufacturing, and development and investment in the territories and countries where we or our customers operate could adversely affect our operating results and our business.
Additionally, on June 23, 2016, the United Kingdom held a referendum and voted in favor of leaving the European Union, or EU. This referendum has created political and economic uncertainty, particularly in the United Kingdom and the EU, and this uncertainty may last for years. Our business could be affected during this period of uncertainty, and perhaps longer, by the impact of the United Kingdom’s referendum. In addition, our business could be negatively affected by new trade agreements between the United Kingdom and other countries, including the United States, and by the possible imposition of trade or other regulatory barriers in the United Kingdom. These possible negative impacts, and others resulting from the United Kingdom’s actual or threatened withdrawal from the EU, may adversely affect our operating results and our customers’ businesses.
Our inability to protect our intellectual property could have a material adverse effect on our business. In addition, third parties may claim that we infringe their intellectual property, and we could suffer significant litigation or licensing expense as a result. We place considerable emphasis on obtaining patent and trade secret protection for significant new technologies, products and processes because of the length of time and expense associated with bringing new products through the development process and into the marketplace. Our success depends in part on our ability to develop patentable products and obtain and enforce patent protection for our products both in the United States and in other countries. We own numerous U.S. and foreign patents, and we intend to file additional applications, as appropriate, for patents covering our products. Patents may not be issued for any pending or future patent applications owned by or licensed to us, and the claims allowed under any issued patents may not be sufficiently broad to protect our technology. Any issued patents owned by or licensed to us may be challenged, invalidated or circumvented, and the rights under these patents may not provide us with competitive advantages. In addition, competitors may design around our technology or develop competing technologies. Intellectual property rights may also be unavailable or limited in some foreign countries, which could make it easier for competitors to capture increased market position. We could incur substantial costs to defend ourselves in suits brought against us or in suits in which we may assert our patent rights against others. An unfavorable outcome of any such litigation could materially adversely affect our business and results of operations.
We also rely on trade secrets and proprietary know-how with which we seek to protect our products, in part, by confidentiality agreements with our collaborators, employees and consultants. These agreements may be breached and we may not have adequate remedies for any breach. In addition, our trade secrets may otherwise become known or be independently developed by our competitors.
Third parties may assert claims against us to the effect that we are infringing on their intellectual property rights. Our Life Technologies subsidiary is party to severalcertain lawsuits in which plaintiffs claim we infringe their intellectual property (Note 9). We could incur substantial costs and diversion of management resources in defending these claims, which could have a material adverse effect on our business, financial condition and results of operations. In addition, parties making these claims could secure a judgment awarding substantial damages, as well as injunctive or other equitable relief, which could effectively block our ability to make, use, sell, distribute, or market our products and services in the United States or abroad. In the event that a claim relating to intellectual property is asserted against us, or third parties not affiliated with us hold pending or issued patents that relate to our products or technology, we may seek licenses to such intellectual property or challenge those patents. However, we may be unable to obtain these licenses on commercially reasonable terms, if at all, and our challenge of the patents may be unsuccessful. Our failure to obtain the necessary licenses or other rights could prevent the sale, manufacture, or distribution of our products and, therefore, could have a material adverse effect on our business, financial condition and results of operations.
Changes in governmental regulations may reduce demand for our products or increase our expenses.We compete in many markets in which we and our customers must comply with federal, state, local and international regulations, such as environmental, health and safety and food and drug regulations. We develop, configure and market our products to meet customer needs created by those regulations. Any significant change in regulations could reduce demand for our products or increase our expenses. For example, many of our instruments are marketed to the pharmaceutical industry for use in discovering and developing drugs. Changes in the U.S. Food and Drug Administration’s regulation of the drug discovery and development process could have an adverse effect on the demand for these products.
IfOur pharma services offerings are highly complex, and if we are unable to provide quality and timely offerings to our securitycustomers, our business could suffer. Our pharma services offerings are highly exacting and complex, due in part to strict quality and regulatory requirements. Our operating results in this business depend on our ability to execute and, when

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Risk Factors (continued)


necessary, improve our quality management strategy and systems, and our ability to effectively train and maintain our employee base with respect to quality management. A failure of our quality control systems could result in problems with facility operations or preparation or provision of products. In each case, such problems could arise for a variety of reasons, including equipment malfunction, failure to follow specific protocols and procedures, problems with raw materials or environmental factors and damage to, or loss of, manufacturing operations. Such problems could affect production of a particular batch or series of batches of products, do not operate as designedrequiring the destruction of such products or a halt of facility production altogether.
In addition, our failure to meet required quality standards may result in our failure to timely deliver products to our customers, which in turn could damage our reputation for quality and failservice. Any such failure could, among other things, lead to detect explosivesincreased costs, lost revenue, reimbursement to customers for lost drug product, registered intermediates, registered starting materials, and active pharmaceutical ingredients, other customer claims, damage to and possibly termination of existing customer relationships, time and expense spent investigating the cause and, depending on the cause, similar losses with respect to other batches or radiation, weproducts. Production problems in our drug and biologic manufacturing operations could be exposedparticularly significant because the cost of raw materials for such manufacturing is often high. If problems in preparation or manufacture of a product or failures to meet required quality standards for that product are not discovered before such product is released to the market, we may be subject to adverse regulatory actions, including product recalls, product seizures, injunctions to halt manufacture and distribution, restrictions on our operations, civil sanctions, including monetary sanctions, and criminal actions. In addition, such problems or failures could subject us to litigation claims, including claims from our customers for reimbursement for the cost of lost or damaged active pharmaceutical ingredients, the cost of which could be significant.
We are subject to product and other liability and related claimsrisks for which we may not have adequate insurance coverage. ProductsWe may be named as a defendant in product liability lawsuits, which may allege that products or services we have provided from our pharma services offerings have resulted or could result in an unsafe condition or injury to consumers. Additionally, products currently or previously sold by our environmental and process instruments and radiation measurement and security instruments businesses include fixed and portable instruments used for chemical, radiation and trace explosives detection. These products are used in airports, embassies, cargo facilities, border crossings and other high-threat facilities for the detection and prevention of terrorist acts. If

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Risk Factors (continued)


any of these products were to malfunction, it is possible that explosive or radioactive material could fail to be detected by our product, which could lead to product liability claims. There are also many other factors beyond our control that could lead to liability claims, such as the reliability and competence of the customers’ operators and the training of such operators.
Any such product liability claims brought against us could be significant and any adverse determination may result in liabilities in excess of our insurance coverage. Although we carry product liability insurance, we cannot be certain that our current insurance will be sufficient to cover these claims or that it can be maintained on acceptable terms, if at all.
Our inability to complete any pending acquisitions or to successfully integrate any new or previous acquisitions could have a material adverse effect on our business. Our business strategy includes the acquisition of technologies and businesses that complement or augment our existing products and services. Certain acquisitions may be difficult to complete for a number of reasons, including the need for antitrust and/or other regulatory approvals. Any acquisition we may complete may be made at a substantial premium over the fair value of the net identifiable assets of the acquired company. Further, we may not be able to integrate acquired businesses successfully into our existing businesses, make such businesses profitable, or realize anticipated cost savings or synergies, if any, from these acquisitions, which could adversely affect our business.
Moreover, we have acquired many companies and businesses. As a result of these acquisitions, we recorded significant goodwill and indefinite-lived intangible assets (primarily tradenames) on our balance sheet, which amount to approximately $21.56$25.36 billion and $1.29 billion, respectively, as of April 1, 2017.March 31, 2018. In addition, we have definite-lived intangible assets totaling $12.53$15.11 billion as of April 1, 2017.March 31, 2018. We assess the realizability of goodwill and indefinite-lived intangible assets annually as well as whenever events or changes in circumstances indicate that these assets may be impaired. We assess the realizability of definite-lived intangible assets whenever events or changes in circumstances indicate that these assets may be impaired. These events or circumstances would generally include operating losses or a significant decline in earnings associated with the acquired business or asset. Our ability to realize the value of the goodwill and intangible assets will depend on the future cash flows of these businesses. These cash flows in turn depend in part on how well we have integrated these businesses. If we are not able to realize the value of the goodwill and intangible assets, we may be required to incur material charges relating to the impairment of those assets.
We are subject to laws and regulations governing government contracts, and failure to address these laws and regulations or comply with government contracts could harm our business by leading to a reduction in revenue associated with these customers. We have agreements relating to the sale of our products to government entities and, as a result, we are subject to various statutes and regulations that apply to companies doing business with the government. The laws

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Risk Factors (continued)


governing government contracts differ from the laws governing private contracts and government contracts may contain pricing terms and conditions that are not applicable to private contracts. We are also subject to investigation for compliance with the regulations governing government contracts. A failure to comply with these regulations could result in suspension of these contracts, criminal, civil and administrative penalties or debarment.
Because we compete directly with certain of our larger customers and product suppliers, our results of operations could be adversely affected in the short term if these customers or suppliers abruptly discontinue or significantly modify their relationship with us. Our largest customer in the laboratory products business is also a significant competitor. Our business may be harmed in the short term if our competitive relationship in the marketplace with certain of our large customers results in a discontinuation of their purchases from us. In addition, we manufacture products that compete directly with products that we source from third-party suppliers. We also source competitive products from multiple suppliers. Our business could be adversely affected in the short term if any of our large third-party suppliers abruptly discontinues selling products to us.
Because we rely heavily on third-party package-delivery services, a significant disruption in these services or significant increases in prices may disrupt our ability to ship products, increase our costs and lower our profitability. We ship a significant portion of our products to our customers through independent package delivery companies, such as Federal Express in the U.S. and DHL in Europe. We also maintain a small fleet of vehicles dedicated to the delivery of our products and ship our products through other carriers, including national and regional trucking firms, overnight carrier services and the U.S. Postal Service. If one or more of these third-party package-delivery providers were to experience a major work stoppage, preventing our products from being delivered in a timely fashion or causing us to incur additional shipping costs we could not pass on to our customers, our costs could increase and our relationships with certain of our customers could be adversely affected. In addition, if one or more of these third-party package-delivery providers were to increase prices, and we were not able to find comparable alternatives or make adjustments in our delivery network, our profitability could be adversely affected.
We are required to comply with a wide variety of laws and regulations, and are subject to regulation by various federal, state and foreign agencies. For example, some of our operationsWe are subject to regulation byvarious local, state, federal, foreign and transnational laws and regulations, which include the operating and security standards of the U.S. Food andFederal Drug Administration (the FDA), the U.S. Drug Enforcement Agency (the DEA), various state boards of pharmacy, state health departments, the U.S. Department of Health and similar international agencies. TheseHuman Services (the DHHS), the European Medicines Agency (the EMA), in Europe, the EU member states and other comparable agencies and, in the future, any changes to such laws and regulations govern a wide variety of product activities, from designcould adversely affect us. In particular, we are subject to laws and developmentregulations concerning current good manufacturing practices and drug safety. Our subsidiaries may be required to labeling, manufacturing, promotion, salesregister for permits and/or licenses with, and distribution. If we failmay be required to comply with the U.S. Foodlaws and regulations of the DEA, the FDA, the DHHS, foreign agencies including the EMA, and other various state boards of pharmacy, state health departments and/or comparable state agencies as well as certain accrediting bodies depending upon the type of operations and location of product distribution, manufacturing and sale.

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Risk Factors (continued)


Drug Administration’s regulationsThe manufacture, distribution and marketing of many of our products and services, including medical devices and pharma services, are subject to extensive ongoing regulation by the FDA, the DEA, the EMA, and other equivalent local, state, federal and non-U.S. regulatory authorities. In addition, we are subject to inspections by these regulatory authorities. Failure by us or thoseby our customers to comply with the requirements of similar international agencies, we may havethese regulatory authorities, including without limitation, remediating any inspectional observations to recall products and/the satisfaction of these regulatory authorities, could result in warning letters, product recalls or cease theirseizures, monetary sanctions, injunctions to halt manufacture and distribution, restrictions on our operations, civil or criminal sanctions, or withdrawal of existing or denial of pending approvals, including those relating to products or facilities. In addition, such a failure could expose us to contractual or product liability claims, contractual claims from our customers, including claims for reimbursement for lost or damaged active pharmaceutical ingredients, as well as ongoing remediation and increased compliance costs, any or all of which would increasecould be significant. We are the sole manufacturer of a number of pharmaceuticals for many of our costscustomers and reducea negative regulatory event could impact our revenues.customers' ability to provide products to their customers.
We are also subject to a variety of federal, state, local and international laws and regulations that govern, among other things, the importation and exportation of products, the handling, transportation and manufacture of substances that could be classified as hazardous, and our business practices in the U.S. and abroad such as anti-corruption, anti-competition and anti-competitionprivacy and data protection laws. AAny noncompliance by us with applicable laws and regulations or the failure to comply with these lawsmaintain, renew or obtain necessary permits and regulationslicenses could result in criminal, civil and administrative penalties.penalties and could have an adverse effect on our results of operations.
Our business could be adversely affected by disruptions at our sites.We rely upon our manufacturing operations to produce many of the products we sell and our warehouse facilities to store products, pending sale. Any significant disruption of

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Risk Factors (continued)


those operations for any reason, such as strikes or other labor unrest, power interruptions, fire, hurricanes or other events beyond our control could adversely affect our sales and customer relationships and therefore adversely affect our business. We have significant operations in California, near major earthquake faults, which make us susceptible to earthquake risk. Although most of our raw materials are available from a number of potential suppliers, our operations also depend upon our ability to obtain raw materials at reasonable prices. If we are unable to obtain the materials we need at a reasonable price, we may not be able to produce certain of our products or we may not be able to produce certain of these products at a marketable price, which could have an adverse effect on our results of operations.
Fluctuations in our effective tax rate may adversely affect our results of operations and cash flows.As a global company, we are subject to taxation in numerous countries, states and other jurisdictions. In preparing our financial statements, we record the amount of tax that is payable in each of the countries, states and other jurisdictions in which we operate. Our future effective tax rate, however, may be lower or higher than experienced in the past due to numerous factors, including a change in the mix of our profitability from country to country, changes in accounting for income taxes and recently enacted and future changes in tax laws in jurisdictions in which we operate. Any of these factors could cause us to experience an effective tax rate significantly different from previous periods or our current expectations, which could have an adverse effect on our business, results of operations and cash flows.
We may incur unexpected costs from increases in fuel and raw material prices, which could reduce our earnings and cash flow. Our primary commodity exposures are for fuel, petroleum-based resins and steel. While we may seek to minimize the impact of price increases through higher prices to customers and various cost-saving measures, our earnings and cash flows could be adversely affected in the event these measures are insufficient to cover our costs.
A significant disruption in, or breach in security of, our information technology systems could adversely affect our business. As a part of our ongoing effort to upgrade our current information systems, we periodically implement new enterprise resource planning software and other software applications to manage certain of our business operations. As we implement and add functionality, problems could arise that we have not foreseen. Such problems could disrupt our ability to provide quotes, take customer orders and otherwise run our business in a timely manner. When we upgrade or change systems, we may suffer interruptions in service, loss of data or reduced functionality. In addition, if our new systems fail to provide accurate pricing and cost data our results of operations and cash flows could be adversely affected.
We also rely on our technology infrastructure, among other functions, to interact with suppliers, sell our products and services, fulfill orders and bill, collect and make payments, ship products, provide services and support to customers, track customers, fulfill contractual obligations and otherwise conduct business. Our systems may be vulnerable to damage or interruption from natural disasters, power loss, telecommunication failures, terrorist attacks, computer viruses, computer denial-of-service attacks, unauthorized access to customer or employee data or company trade secrets, and other attempts to harm our systems. Certain of our systems are not redundant, and our disaster recovery planning is not sufficient for every eventuality. Despite any precautions we may take, such problems could result in, among other consequences, interruptions in our services, which could harm our reputation and financial results. Any of the cyber-attacks, breaches or other disruptions or damage described above, if significant, could materially interrupt our operations, delay production and shipments, result in theft of our and our customers’ intellectual property and trade secrets, damage customer, and business partner and employee relationships and our reputation or result in defective products or services, legal claims and proceedings, liability and penalties under privacy laws and increased cost for security and remediation, each of which could adversely affect our business and financial results.
Our debt may restrict our investment opportunities or limit our activities.As of April 1, 2017,March 31, 2018, we had approximately $17.07$20.94 billion in outstanding indebtedness. In addition, we have availability to borrow under a revolving credit facility that provides for up to $2.50 billion of unsecured multi-currency revolving credit. We may also obtain additional long-term debt and lines of credit to meet future financing needs, which would have the effect of increasing our total leverage.

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Risk Factors (continued)


Our leverage could have negative consequences, including increasing our vulnerability to adverse economic and industry conditions, limiting our ability to obtain additional financing and limiting our ability to acquire new products and technologies through strategic acquisitions.
Our ability to make scheduled payments, refinance our obligations or obtain additional financing will depend on our future operating performance and on economic, financial, competitive and other factors beyond our control. Our business may not generate sufficient cash flow to meet our obligations. If we are unable to service our debt, refinance our existing debt or obtain additional financing, we may be forced to delay strategic acquisitions, capital expenditures or research and development expenditures.
Additionally, the agreements governing our debt require that we maintain certain financial ratios, and contain affirmative and negative covenants that restrict our activities by, among other limitations, limiting our ability to incur additional

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THERMO FISHER SCIENTIFIC INC.
Risk Factors (continued)


indebtedness, merge or consolidate with other entities, make investments, create liens, sell assets and enter into transactions with affiliates. The covenants in our revolving credit facility and our term facility (each, a “Facility” and together, the “Facilities”)(the Facility) include a totalConsolidated Leverage Ratio (total debt-to-Consolidated EBITDA) and a Consolidated Interest Coverage Ratio (Consolidated EBITDA ratio and an interest coverage ratio.to Consolidated Interest Expense), as such terms are defined in the Facility. Specifically, the company has agreed that, so long as any lender has any commitment under the revolving credit facility,Facility, any letter of credit is outstanding under the revolving credit facility,Facility, or any loan or other obligation is outstanding under the revolving credit facility,Facility, it will not permit (as the following terms are defined in the credit agreement governing the revolving credit facility) themaintain a maximum Consolidated Leverage Ratio (the ratio of consolidated Indebtedness to Consolidated EBITDA) to be greater than 4.0 to 4.0:1.0 asthrough the second quarter of the last day of any fiscal quarter for the first two quarters of 2017 with such ratio2018 and then stepping down to 3.5 to 3.5:1.0 for each fiscalthe third quarter of 2018 and thereafter. The company’s term facility includes Consolidated Leverage Ratio covenants substantively the same as the covenant included in the revolving credit facility.
The company has also agreed that so long as any lender has any commitment under the revolving credit facilityFacility or any letter of credit is outstanding under the revolving credit facility,Facility, or any loan or other obligation is outstanding under anythe Facility, (including the term loan and bridge facilities), it will not permit themaintain a minimum Consolidated Interest Coverage Ratio (the ratio of Consolidated EBITDA to Consolidated Interest Expense) to be less than 3.0 to 3.0:1.0 as atof the last day of any fiscal quarter.
Our ability to comply with these financial restrictions and covenants is dependent on our future performance, which is subject to prevailing economic conditions and other factors, including factors that are beyond our control such as foreign exchange rates and interest rates. Our failure to comply with any of these restrictions or covenants may result in an event of default under the applicable debt instrument, which could permit acceleration of the debt under that instrument and require us to prepay that debt before its scheduled due date. Also, an acceleration of the debt under certain of our debt instruments would trigger an event of default under other of our debt instruments.


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THERMO FISHER SCIENTIFIC INC.

Item 2.Unregistered Sales of Equity Securities and Use of Proceeds
Issuer Purchases of Equity Securities
A summary of theThere was no share repurchase activity for the company's first quarter of 2017 follows:2018. On July 7, 2016, the Board of Directors authorized the repurchase of up to $1.50 billion of the company’s common stock. At March 31, 2018, $500 million was available for future repurchases of the company’s common stock under this authorization.
Period Total Number of Shares Purchased
 Average Price Paid per Share
 Total Number of Shares Purchased as Part of Publicly Announced Plans or Programs (1)
 
Maximum Dollar Amount of Shares That May Yet Be Purchased Under the Plans or Programs(1)
(in millions)

         
Fiscal January (Jan. 1 - Feb. 4) 3,420,712
 $146.17
 3,420,712
 $750.0
Fiscal February (Feb. 5 - Mar. 4) 
 
 
 750.0
Fiscal March (Mar. 5 - Apr. 1) 
 
 
 750.0
         
Total First Quarter 3,420,712
 $146.17
 3,420,712
 $750.0
(1)On July 7, 2016, the Board of Directors authorized the repurchase of up to $1.50 billion of the company’s common stock. All of the shares of common stock repurchased by the company during the first quarter of 2017 were purchased under this program. In April 2017, the company purchased an additional $250 million of the company's common stock under this authorization.

Item 6.Exhibits
See Exhibit Index on page 4546.


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SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
Date:May 5, 20174, 2018THERMO FISHER SCIENTIFIC INC.
   
   
   
  /s/ Stephen Williamson
  Stephen Williamson
  Senior Vice President and Chief Financial Officer
   
   
   
  /s/ Peter E. Hornstra
  Peter E. Hornstra
  Vice President and Chief Accounting Officer


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THERMO FISHER SCIENTIFIC INC.
EXHIBIT INDEX


Exhibit
Number
 Description of Exhibit
10.1 
3.1Bylaws
Summary of the Registrant, as amended and effective as of March 1, 2017 (filed as Exhibit 3.12018 Annual Cash Incentive Plan Matters (set forth in Item 5.02 to the Registrant’s Current Report on Form 8-K filed March 2, 20171, 2018 [File No. 1-8002]No.1-8002] under the heading "Compensatory Arrangements of Certain Officers" and incorporated in this document by reference).*
4.110.2 Fifteenth Supplemental Indenture,
10.3
Registrant.*

31.1 
31.2 
32.1 
32.2 
101.INS XBRL Instance Document.
101.SCH XBRL Taxonomy Extension Schema Document.
101.CAL XBRL Taxonomy Calculation Linkbase Document.
101.DEF XBRL Taxonomy Definition Linkbase Document.
101.LAB XBRL Taxonomy Label Linkbase Document.
101.PRE XBRL Taxonomy Presentation Linkbase Document.
  The Registrant agrees, pursuant to Item 601(b)(4)(iii)(A) of Regulation S-K, to furnish to the Commission, upon request, a copy of each instrument with respect to long-term debt of the Registrant or its consolidated subsidiaries.
 _______________________
*Indicates management contract or compensatory plan, contract or arrangement.
** Certification is not deemed “filed”"filed" for purposes of Section 18 of the Exchange Act or otherwise subject to the liability of that section. Such certification is not deemed to be incorporated by reference into any filing under the Securities Act or the Exchange Act except to the extent that the registrant specifically incorporates it by reference.
Attached as Exhibit 101 to this report are the following formatted in XBRL (Extensible Business Reporting Language): (i) Consolidated Balance Sheet at April 1, 2017March 31, 2018 and December 31, 2016,2017, (ii) Consolidated Statement of Income for the three months ended March 31, 2018 and April 1, 2017 and April 2, 2016, (iii) Consolidated Statement of Comprehensive Income for the three months ended March 31, 2018 and April 1, 2017, and April 2, 2016, (iv) Consolidated Statement of Cash Flows for the three months ended March 31, 2018 and April 1, 2017, and April 2, 2016, (v) Consolidated Statement of Shareholders’ Equity for the three months ended March 31, 2018 and April 1, 2017 and April 2, 2016 and (vi) Notes to Consolidated Financial Statements.

4546