SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

 


FORM 10-Q

 


(Mark One)

xQUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the Quarterly Period Ended SeptemberJune 30, 20062007

Or

 

¨TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period fromto            to

Commission file number: 000-30975

 


TRANSGENOMIC, INC.

(Exact name of registrant as specified in its charter)

 


 

Delaware 911789357

(State or other jurisdiction of

incorporation or organization)

 

(I.R.S. Employer

Identification No.)

 

12325 Emmet Street, Omaha, Nebraska 68164
(Address of principal executive offices) (Zip Code)

(402) 452-5400

(Registrant’s telephone number, including area code)

 


Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months and (2) has been subject to such filing requirements for the past 90 days.    Yes  x    No  ¨

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, or a non-accelerated filer. See definition of “accelerated filer” and “large accelerated filer” in Rule 12b-2 of the Securities Exchange Act of 1934.

Large accelerated filer  ¨    Accelerated filer  ¨    Non-accelerated filer  x

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Securities Exchange Act of 1934)    Yes  ¨    No  x

As of NovemberAugust 14, 2006,2007, the number of shares of common stock outstanding was 49,189,672.

 



TRANSGENOMIC, INC.

INDEX

 

     Page No.

PART I. FINANCIAL INFORMATION

  3

Item 1.

 

Financial Statements

  3
 

Unaudited Condensed Consolidated Balance Sheets as of SeptemberJune 30, 20062007 and December 31, 20052006

  3
 

Unaudited Condensed Consolidated Statements of Operations for the Three and NineSix Months Ended SeptemberJune 30, 20062007 and 20052006

  4
 

Unaudited Condensed Consolidated Statements of Stockholders’sStockholders’ Equity for the NineSix Months Ended SeptemberJune 30, 20062007

  5
 

Unaudited Condensed Consolidated Statements of Cash Flows for the NineSix Months Ended SeptemberJune 30, 20062007 and 20052006

  6
 

Notes to Unaudited Condensed Consolidated Financial Statements

  7

Item 2.

 

Management’s Discussion and Analysis of Financial Condition and Results of Operations

  1816

Item 3.

 

Quantitative and Qualitative Disclosures About Market Risk

  2522

Item 4.

 

Controls and Procedures

  2522

PART II. OTHER INFORMATION

  2523

Item 1.

 

Legal Proceedings

  2523

Item 1A.

 

Risk Factors

  2623

Item 2.4.

 

Unregistered Sales of Equity Securities and Use of Proceeds

26

Item 4.

Submission of Matters to a Vote of Security Holders

  2623

Item 6.

 

Exhibits

  2623

Signatures

  2824

PART I. FINANCIAL INFORMATION

Item 1. Financial Statements

Item 1.Financial Statements

TRANSGENOMIC, INC. AND SUBSIDIARIES

UNAUDITED CONDENSED CONSOLIDATED BALANCE SHEETS

(Dollars in thousands except per share data)

 

  

September 30,

2006

 December 31,
2005
   

June 30,

2007

(unaudited)

 

December 31,

2006

 
ASSETS      

CURRENT ASSETS:

      

Cash and cash equivalents

  $7,305  $6,736   $7,883  $5,868 

Accounts receivable (net of allowances for bad debts of $376 and $615, respectively)

   5,349   7,542 

Accounts receivable (net of allowances for doubtful accounts of $476 and $444, respectively)

   6,474   6,525 

Inventories

   2,336   2,990    3,243   2,672 

Prepaid expenses and other current assets

   732   653    571   540 

Current assets of discontinued operations

   —     197    4   —   
              

Total current assets

   15,722   18,118    18,175   15,605 
              

PROPERTY AND EQUIPMENT:

      

Equipment

   10,188   10,108    10,416   10,345 

Furniture and fixtures

   3,808   3,797    3,822   3,820 
              
   13,996   13,905    14,238   14,165 

Less: accumulated depreciation

   12,235   11,328 

Less: Accumulated depreciation

   13,008   12,667 
              
   1,761   2,577    1,230   1,498 

OTHER ASSETS:

      

Goodwill

   638   638    638   638 

Other assets

   923   1,074    733   853 

Non-current assets of discontinued operations

   2,668   2,933    —     2,773 
              
  $21,712  $25,340   $20,776  $21,367 
              
LIABILITIES AND STOCKHOLDERS’ EQUITY      

CURRENT LIABILITIES:

      

Accounts payable

  $1,437  $1,796   $1,386  $1,558 

Other accrued expenses

   2,800   3,114    3,454   2,898 

Accrued compensation

   684   602    491   689 

Current liabilities of discontinued operations

   280   1,922    176   184 
              

Total current liabilities

   5,201   7,434    5,507   5,329 

Other long-term liabilities

   129   —   
              

Total liabilities

   5,201   7,434    5,636   5,329 

COMMITMENTS AND CONTINGENCIES (Note F)

   

COMMITMENTS AND CONTINGENCIES

   

STOCKHOLDERS’ EQUITY:

      

Preferred stock, $.01 par value, 15,000,000 shares authorized, none outstanding

   —     —   

Common stock, $.01 par value, 100,000,000 and 60,000,000 shares authorized, respectively, 49,189,672 and 49,182,121 shares outstanding, respectively

   497   497 

Preferred stock, $0.01 par value, 15,000,000 shares authorized, none outstanding

   —     —   

Common stock, $0.01 par value, 100,000,000 shares authorized, 49,189,672 shares outstanding

   497   497 

Additional paid-in capital

   138,957   138,800    139,012   138,966 

Accumulated other comprehensive income

   1,541   703    2,255   2,100 

Accumulated deficit

   (124,484)  (122,094)   (126,624)  (125,525)
              

Total stockholders’ equity

   16,511   17,906    15,140   16,038 
              
  $21,712  $25,340   $20,776  $21,367 
              

See notes to unaudited condensed consolidated financial statements.

TRANSGENOMIC, INC. AND SUBSIDIARIES

UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

(Dollars in thousands except per share data)

 

  

Three Months Ended

September 30,

 Nine Months Ended
September 30,
   

Three Months Ended

June 30,

 

Six Months Ended

June 30,

 
  2006 2005 2006 2005   2007 2006 2007 2006 

NET SALES

  $4,919  $6,663  $17,605  $20,480   $6,272  $6,189  $11,494  $12,686 

COST OF GOODS SOLD

   2,607   3,548   9,261   10,480    2,859   3,140   5,373   6,654 
                          

Gross profit

   2,312   3,115   8,344   10,000    3,413   3,049   6,121   6,032 

OPERATING EXPENSES:

          

Selling, general and administrative

   3,305   2,692   8,834   9,284    3,067   2,820   6,047   5,529 

Research and development

   586   510   1,721   1,697    492   531   1,550   1,135 

Impairment Charge

   —     247   —     247 

Restructuring costs

   624   —     624   —   
                          
   3,891   3,449   10,555   11,228    4,183   3,351   8,221   6,664 
                          

LOSS FROM OPERATIONS

   (1,579)  (334)  (2,211)  (1,228)   (770)  (302)  (2,100)  (632)

OTHER INCOME (EXPENSE):

          

Interest expense

   (7)  (181)  (7)  (1,921)

Interest income, net of interest expense

   79   44   141   88 

Other, net

   68   (3)  156   14    —     —     4   —   

Gain on sale of investment

   938   —     938   —   
                          
   61   (184)  149   (1,907)   1,017   44   1,083   88 
                          

LOSS BEFORE INCOME TAXES

   (1,518)  (518)  (2,062)  (3,135)

INCOME (LOSS) BEFORE INCOME TAXES

   247   (258)  (1,017)  (544)

INCOME TAX EXPENSE

   7   8   24   26    14   —     19   17 
                          

LOSS FROM CONTINUING OPERATIONS

   (1,525)  (526)  (2,086)  (3,161)

INCOME(LOSS) FROM DISCONTINUED OPERATIONS, NET OF TAX

   (164)  637   (304)  (618)

INCOME (LOSS) FROM CONTINUING OPERATIONS

   233   (258)  (1,036)  (561)

INCOME (LOSS) FROM DISCONTINUED OPERATIONS, NET OF TAX

   (7)  (125)  66   (139)
                          

NET INCOME (LOSS)

  $(1,689) $111  $(2,390) $(3,779)  $226  $(383) $(970) $(700)
                          

BASIC AND DILUTED LOSS PER SHARE:

          

From continuing operations

  $(0.03) $(0.02) $(0.04) $(0.10)  $0.00  $(0.01) $(0.02) $(0.01)

From discontinued operations

   0.00   0.02   (0.01)  (0.02)   0.00   0.00   0.00   0.00 
                          
  $(0.03) $(0.00) $(0.05) $(0.12)  $0.00  $(0.01) $(0.02) $(0.01)
                          

BASIC AND DILUTED WEIGHTED AVERAGE SHARES OUTSTANDING

   49,189,672   34,242,966   49,188,040   32,837,078 

BASIC WEIGHTED AVERAGE SHARES
OUTSTANDING

   49,189,672   49,189,672   49,189,672   49,187,211 

DILUTED WEIGHTED AVERAGE SHARES
OUTSTANDING

   62,141,863   49,189,672   49,189,672   49,187,211 

See notes to unaudited condensed consolidated financial statements.

TRANSGENOMIC, INC. AND SUBSIDIARIES

UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY

NineSix Months Ended SeptemberJune 30, 20062007

(Dollars in thousands except per share data)

 

  Common Stock  

Additional

Paid-in

Capital

  

Accumulated

Deficit

  

Accumulated

Other

Comprehensive

Income (Loss)

  

Total

   Common Stock           

Outstanding

Shares

  

Par

Value

     

Outstanding

Shares

  

Par

Value

  

Additional

Paid-in

Capital

  

Accumulated

Deficit

 

Accumulated

Other

Comprehensive

Income (Loss)

 Total 

Balance, January 1, 2006

  49,182,121  $497  $138,800  $(122,094) $703  $17,906 

Balance, December 31, 2006

  49,189,672  $497  $138,966  $(125,525) $2,100  $16,038 

Cumulative effect of adoption of FIN 48 (Note H)

  —     —     —     (129)  —     (129)
                   

Balance, January 1, 2007

  49,189,672  $497  $138,966  $(125,654) $2,100  $15,909 

Net loss

  —     —     —     (2,390)  (2,390)  (2,390)  —     —     —     (970)  (970)  (970)

Other comprehensive income (loss):

          

Other comprehensive loss:

          

Foreign currency translation adjustment

  —     —     —     —     838   838   —     —     —     —     155   155 
            

Comprehensive loss

  —     —     —     —     (1,432)  —     —     —     —     —     (815)  —   

Stock-based compensation

  —     —     152   —     —     152   —     —     46   —     —     46 

Issuance of shares for employee stock purchase plan

  7,551   —     5   —     —     5 
                                      

Balance, September 30, 2006

  49,189,672  $497  $138,957  $(124,484) $1,541  $16,511 

Balance, June 30, 2007

  49,189,672  $497  $139,012  $(126,624) $2,255  $15,140 
                                      

See notes to unaudited condensed consolidated financial statements.

TRANSGENOMIC, INC. AND SUBSIDIARIES

UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(Dollars in thousands)

 

  

Nine Months Ended

September 30,

   

Six Months Ended

June 30,

 
  2006 2005   2007 2006 

CASH FLOWS FROM OPERATING ACTIVITIES:

   

CASH FLOWS PROVIDED BY (USED IN) OPERATING ACTIVITIES:

   

Net loss

  $(2,390) $(3,779)  $(970) $(700)

Adjustments to reconcile net loss to net cash flows from operating activities:

   

Adjustments to reconcile net loss to net cash flows provided by (used in) operating activities:

   

Depreciation and amortization

   1,361   3,294    742   956 

Impairment charge

   437   247 

Non-cash financing costs

   —     1,298 

Non-cash, stock based compensation

   152   —   

Gain on sale of securities

   —     (9)

Loss on sale of assets

   15   —   

Other

   —     2 

Non-cash, stock-based compensation

   46   —   

(Gain) Loss on sale of investment and assets

   (1,034)  7 

Changes in operating assets and liabilities:

      

Accounts receivable

   2,585   (626)   149   1,131 

Inventories

   805   960    (567)  785 

Prepaid expenses and other current assets

   26   650    (28)  (90)

Accounts payable

   (820)  (912)   (216)  (477)

Accrued expenses

   (1,691)  (3,101)   314   (947)
              

Net cash flows from (used in) operating activities

   480   (1,976)

Net cash flows provided by (used in) operating activities

   (1,564)  665 
              

CASH FLOWS FROM INVESTING ACTIVITIES:

   

Proceeds from the maturities and sales of available for sale securities

   —     617 

CASH FLOWS PROVIDED BY (USED IN) INVESTING ACTIVITIES:

   

Purchase of property and equipment

   (228)  (554)   (181)  (178)

Change in other assets

   (54)  34    (119)  (41)

Proceeds from asset sales

   95   139    3,872   40 
              

Net cash flows from (used in) investing activities

   (187)  236 

Net cash flows provided by (used in) investing activities

   3,572   (179)
              

CASH FLOWS FROM FINANCING ACTIVITIES:

   

Net change in credit line

   —     2,519 

Payments on term note

   —     (178)

CASH FLOWS PROVIDED BY FINANCING ACTIVITIES:

   

Issuance of common stock

   5   (35)   —     5 
              

Net cash flows from financing activities

   5   2,306 

Net cash flows provided by financing activities

   —     5 
              

EFFECT OF FOREIGN CURRENCY EXCHANGE RATE CHANGES ON CASH

   271   (207)   7   135 
              

NET CHANGE IN CASH AND CASH EQUIVALENTS

   569   359    2,015   626 

CASH AND CASH EQUIVALENTS AT BEGINNING OF YEAR

   6,736   1,002    5,868   6,736 
              

CASH AND CASH EQUIVALENTS AT END OF PERIOD

  $7,305  $1,361   $7,883  $7,362 
              

SUPPLEMENTAL CASH FLOW INFORMATION

      

Cash paid during the period for:

      

Interest

  $—    $491   $5  $—   

Income taxes, net

   24   27    19   17 

Non-cash transactions:

   

Available for sale securities acquired for goods and services

   —     2,099 

Conversions of debt to equity

   —     2,535 

See notes to unaudited condensed consolidated financial statements.

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

NineSix Months Ended SeptemberJune 30, 20062007 and 20052006

(Dollars in thousands except per share data)data and as noted)

A. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

A.BUSINESS DESCRIPTION

Business Description.

Transgenomic, Inc., a Delaware corporation, and its subsidiaries (the “Company”) provideprovides innovative products and services for the synthesis, purification and analysis of nucleic acids. The Company’s products and services include automated instrument systems, associated consumables, and genetic variation discovery services. The Company develops, assembles, manufactures and markets its products and services toacids used in the life sciences industry to be used infor research focused on molecular genetics of humans and other organisms. Such research could lead to development of new diagnostics and therapeutics. The Company’s business plan is to participate in the value chain associated with these activities by providing key technology, tools, consumables, biochemical reagents and services to entities engaged in basic biomedical research and the development of diagnostics and therapeutic agents.

diagnostics. The Company develops, assembles, manufactures and markets versatile products andalso provides genetic variation analytical services to the medical research, clinical and pharmaceutical markets for use in genetic variation analysis. Products and services are sold through a direct sales force in the United States and throughout much of Western Europe. For the rest of the world, products and services are sold through more than 25 dealers and distributors located in those local markets. Net sales are categorized as bioinstruments, bioconsumables and discovery services.

 

 

 

Bioinstruments. The Company’s flagship product is the WAVE® system System which has broad applicability to genetic variation detection in both molecular genetic research and molecular diagnostics. There wasis a world-wideworldwide installed base of over 1,3001,375 WAVE® systems Systems as of SeptemberJune 30, 2006.2007. The Company also sells complementary equipment platforms manufactureddistributes bioinstruments produced by others (“OEM Instruments”).other manufacturers through its sales and distribution network. Service contracts to maintain installed systems are sold and supported by technical support personnel.

 

 

 

Bioconsumables. The installed WAVE® base generatesand some third-party installed platforms generate a demand for consumables that are required for the system’s continued operation. The Company develops, manufactures and sells these products. In addition, the Company manufactures and sells consumable products that can be used on a number of equipment platforms manufactured by others. The Company’s proprietary bioconsumablemultiple, independent platforms. These products include SURVEYOR® Nuclease and a range of HPLC separation columns.

 

Discovery Services. The Company provides various genetic laboratory services through a contract research lab in Gaithersburg, Maryland and a second laboratory in Omaha, Nebraska thatNebraska. The lab in Omaha operates in a Good Laboratory Practices (“GLP”) compliant environment and is certified under the Clinical Laboratory Improvement Amendment. The services provided by the Company’s laboratories primarily include (1) genomic researchbiomarker analysis services to pharmaceutical and biopharmaceutical companies to support preclinical and clinical development of targeted therapeutics;therapeutics, and (2) molecular-based medical testing services for hematology, oncology and certain inherited diseases for physicians and third-party laboratories.

Historically, the Company operated a segment (the “Nucleic Acids operating segment”) that developed, manufactured and marketed chemical building blocks for nucleic acid synthesis to biotechnology, pharmaceutical and oligonucleotide synthesis companies and research institutions throughout the world.synthesis. In the fourth quarter of 2005, the Company implemented a plan to exit the Nucleic Acids operating segment and during the three months ended March 31, 2007, the Company completed the sale of the remaining assets associated with this operating segment. Accordingly, the assets and results of thisthe Nucleic Acids operating segment are reflected as discontinued operations for all periods presented.presented in this filing.

Although the Company has experienced declining sales and recurring net losses (resulted(resulting in an accumulated deficit of $124,484$127 million at SeptemberJune 30, 2006)2007), management believes existing sources of liquidity, including cash and cash equivalents of $7,305,$7.9 million, are sufficient to meet expected cash needs through 2007. The Company will need to increase net sales and further reduce operating expenses in order to meet its liquidity needs for the foreseeable future.existing business on a long-term basis. The Company has announced consolidation plans which are underway and will help reduce operating costs. There is no assurance that the Company will be able to increase net sales or further reduce expenses and, accordingly, the Company may not have sufficient sources of liquidity to continue operations indefinitely. If necessary, management believes they can further reduce costs and expenses to conserve working capital. However, such cost and expense reductions could have an adverse impact on the Company’s new product pipeline and ultimately net sales. The Company could also pursue additional financing, but ultimately, the Company must achieve sufficient net sales to consistently generate net income and cash flows from operations.

B.SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

Principles of Consolidation.

The consolidated financial statements include the accounts of Transgenomic, Inc. and its wholly-owned subsidiaries. All intercompany balances and transactions have been eliminated in consolidation.

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS - Continued

Nine Months Ended September 30, 2006 and 2005

(Dollars in thousands except per share data)

Cash and Cash Equivalents.

Cash and cash equivalents include cash and temporary investments with original maturities at acquisition of three months or less.

Accounts Receivable.

Accounts receivable are shown net of allowance for doubtful accounts. The following is a summary of activity for the allowance for doubtful accounts during the three and nine months ended September 30, 2006 and 2005:

   

Three Months Ended

September 30,

  

Nine Months Ended

September 30,

   2006  2005  2006  2005

Beginning balance

  $378  $670  $615  $701

Charges to income

   74   —     29   —  

Deductions from reserves

   76   44   268   75
                

Ending balance

  $376  $626  $376  $626
                

While payment terms are generally 30 days, the Company has also provided extended payment terms of up to 90 days in certain cases.

Inventories.

Inventories are stated at the lower of cost or market. Cost is computed using standard costs for finished goods and average or latest actual cost for raw materials and work in process.

Property and Equipment.

Property and equipment are carried at cost. Depreciation is computed by the straight-line method over the estimated useful lives of the related assets as follows:

Buildings

15 years

Leasehold improvements

3 to 7 years

Furniture and fixtures

5 to 7 years

Production equipment

5 to 7 years

Computer equipment

3 to 5 years

Research and development equipment

3 to 5 years

Demonstration equipment

3 to 5 years

Depreciation and amortization totaled $405 and $1,193 during the three months ended September 30, 2006 and 2005, respectively, of which $312 and $433, respectively, related to depreciation of property and equipment from continuing operations. Depreciation and amortization totaled $1,361 and $3,294 during the nine months ended September 30, 2006 and 2005, respectively, of which $1,033 and $1,397, respectively, related to depreciation of property and equipment from continuing operations.

Goodwill and other Intangible Assets

Statement of Financial Accounting Standards (“SFAS”) No. 142,Goodwill and Other Intangible Assets,provides that goodwill and other intangible assets with indefinite lives will not be amortized, but will be tested for impairment annually. The Company performs this impairment analysis during the fourth quarter of each year. Impairment occurs when the carrying value is not recoverable and the fair value of the asset is less than the carrying value. If impaired, the asset’s carrying value is reduced to its fair value. Identifiable intangible assets with definite lives are amortized over their estimated useful lives and tested for impairment as events or changes in circumstances indicate the carrying amount of the asset may be impaired.

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS - Continued

Nine Months Ended September 30, 2006 and 2005

(Dollars in thousands except per share data)

Other Assets.

Other assets include capitalized software, intellectual property, patents, deferred financing costs and other long-term assets.

Capitalized Software. The Company capitalized software development costs for products offered for sale in accordance with SFAS No. 86,Accounting for the Costs of Computer Software to be Sold, Leased or Otherwise Marketed. This Standard allows for the capitalization of certain development costs once a software product has reached technological feasibility. The Company capitalized no software development costs during the three or nine months ended September 30, 2006 or 2005.

Intellectual Property. Initial costs paid to license intellectual property from third parties are capitalized and amortized using the straight line method over the license period. Ongoing royalties related to such licenses are expensed as incurred.

Patents. The Company capitalizes external legal costs, filing fees and other expenses associated with obtaining patents and amortizes these costs using the straight-line method over the shorter of the legal life of the patent (17 to 20 years depending on when issued) or its economic life beginning on the date the patent is issued.

Deferred Financing Costs. Certain financing costs are capitalized and amortized to interest expense over the life of the related financing.

Other Long-Term Assets. Other long-term assets consist primarily of demonstration inventory that has been at customer or prospective customer sites for greater than one year and security deposits on leased facilities. Long-term demonstration inventory is stated at the lower of cost or market.

Stock Based Compensation.

All employee stock options that existed at December 31, 2005 were fully vested at that date. Stock options issued during 2006 are granted at market price on the date of grant, have ten-year contractual terms, and vest no later than three years from the date of grant. None of the stock options outstanding at September 30, 2006 are subject to performance or market-based vesting conditions.

The Company adopted Financial Accounting Standards Board (FASB) Statement No. 123(R),Share-Based Payment (FAS 123(R)), on January 1, 2006. FAS 123(R) requires the Company to measure and recognize compensation expense for all stock-based awards (stock options) made to employees and directors, including stock options. Compensation expense is based on the calculated fair value of the awards as measured at the grant date and is expensed ratably over the service period of the awards (generally the vesting period). The fair value of stock options is determined by using the Black-Scholes option pricing model. The Company elected to use the modified prospective transition method as permitted by FAS 123(R) and did not restate financial results for prior periods. The adoption of this standard to stock options issued prior to December 31, 2005 had no material impact on the Company’s financial position, results of operations or cash flows.

Prior to the adoption of FAS 123(R), the Company applied the recognition and measurement principles of Accounting Principles Board Opinion No. 25,Accounting for Stock Issued to Employees, and related interpretations. No stock-based employee compensation expense related to stock option grants was reflected in net income, as all options granted under those plans had a grant price equal to the market value of our common stock on the date of grant. The following table details the effect on net income and earnings per share had compensation expense for all stock-based awards, including stock options, been recorded in the three and nine months ended September 30, 2005 based on the fair value method under FASB Statement No. 123,Accounting for Stock-Based Compensation.

   

For Three Months

September 30,
2005

  

For Nine Months

September 30,
2005

 

Net Income (Loss):

   

As reported

  $111  $(3,779)

Pro forma

  $(250) $(4,283)

Basic and Diluted Loss Per Share:

   

As reported

  $0.00  $(0.12)

Pro forma

  $(0.00) $(0.13)

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS - Continued

Nine Months Ended September 30, 2006 and 2005

(Dollars in thousands except per share data)

The fair value of each option grant was estimated on the date of grant using the Black-Scholes option pricing model with the following assumptions:

   2006 2005

Risk-free interest rate

  4.68% 3.10% to 6.53%

Dividend yield

  0% 0%

Expected life (years)

  5 years 3 years

Volatility

  89.14% 35% to 100%

Income Taxes.

Deferred tax assets and liabilities are determined based on the differences between the financial reporting and tax basis of assets and liabilities at each balance sheet date using tax rates expected to be in effect in the year the differences are expected to reverse. Deferred tax assets are reduced by a valuation allowance to the extent that it is more likely than not that they will not be realized.

Revenue Recognition.

Revenue (referred to as “net sales”) on the sales of products is recognized in accordance with the terms of the sales arrangement. Such recognition is based on receipt of an unconditional customer order and transfer of title and risk of ownership to the customer, typically upon shipment of the product. The Company’s sales terms do not provide for the right of return unless the product is damaged or defective. Net sales from certain services associated with our analytical instruments, to be performed subsequent to shipment of the products, is deferred and recognized when the services are provided. Such services, mainly limited to installation and training services that are not essential to the functionality of the instruments, typically are performed in a timely manner subsequent to shipment of the instrument. The Company also enters into various service contracts that cover installed WAVE® systems. These contracts cover specific time periods and net sales associated with these contracts is deferred and recognized over the service period. At September 30, 2006 and December 31, 2005, deferred revenue mainly associated with the Company’s service contracts was approximately $1,604 and $2,124, respectively.

Research and Development.

Research and development costs are charged to expense when incurred.

Translation of Foreign Currency.

Financial statements of subsidiaries outside the U.S. are measured using the local currency as the functional currency. The adjustments to translate those amounts into U.S. dollars are accumulated in a separate account in stockholders’ equity and are included in accumulated other comprehensive income. Foreign currency transaction gains or losses resulting from changes in currency exchange rates are included in the determination of net income. Foreign currency transaction adjustments from continuing operations reduced net loss by $98 and $139 during the nine months ended September 30, 2006 and the three months ended September 30, 2005, respectively and increased net loss by $83 and $322 during the three months ended September 30, 2006 and the nine months ended September 30, 2005, respectively.

Comprehensive Income.

Accumulated other comprehensive income at September 30, 2006 and December 31, 2005 consisted of foreign currency translation adjustments, net of applicable tax of zero. The Company deems its foreign investments to be permanent in nature and does not provide for taxes on currency translation adjustments arising from converting its investments in a foreign currency to U.S. dollars.

Fair Value of Financial Instruments.

The carrying amount of the Company’s cash and cash equivalents, receivables, accounts payable and accrued expenses approximate fair value because of the short maturity of those instruments. The Company derives the fair value of its investments based on quoted market prices.

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS - Continued

Nine Months Ended September 30, 2006 and 2005

(Dollars in thousands except per share data)

Earnings (Loss) Per Share.

Basic earnings (loss) per share is calculated based on the weighted-average number of common shares outstanding during each period. Diluted earnings (loss) per share include shares issuable upon exercise of outstanding stock options and warrants or conversion of convertible notes, where dilutive. Potentially dilutive securities totaling 13,778,841 and 13,625,675 at September 30, 2006 and December 31, 2005, respectively, have been excluded from the computation of diluted earnings per share as they have an antidilutive effect.

Recently Issued Accounting Pronouncements

In December 2004, the FASB issued SFAS No.153, “Exchanges of Nonmonetary Assets.” This statement addresses the prospective measurement for nonmonetary exchanges of nonmonetary assets. It specifies that a nonmonetary exchange has commercial substance if the future cash flows of the entity are expected to change significantly as a result of the exchange. SFAS 153 was effective for the Company beginning July 1, 2006. The Company is assessing the final impact of this standard on its financial position, results of operations or cash flows.

In July 2006, the FASB issued Interpretation (“FIN”) No. 48, “Uncertainty in Income Taxes.” FIN 48 applies to all tax positions within the scope of Statement 109 and clarifies when and how to recognize tax benefits in the financial statements with a two-step approach of recognition and measurement. FIN 48 will become effective in the first quarter of 2007. Management continues to evaluate the effect that the adoption of FIN 48 will have on the Company’s consolidated results of operations and financial position.

In September 2006, the SEC issued Staff Accounting Bulletin. 108,Considering the Effects of Prior Year Misstatements when Quantifying Misstatements in Current Year Financial Statements (SAB 108). SAB 108 provides interpretive guidance on how the effects of prior-year uncorrected misstatements should be considered when quantifying misstatements in current year financial statements. SAB 108 requires registrants to quantify misstatements using both an income statement and balance sheet approach and then evaluate whether either approach results in a misstatement that, when all relevant quantitative and qualitative factors are considered, is material. If prior year errors that had been previously considered immaterial are now considered material based on either approach, no restatement is required so long as management properly applied its previous approach and all relevant facts and circumstances were considered. If prior year’s financial statements are not restated, the cumulative effect adjustment is recorded in opening accumulated earnings (deficit) as of the beginning of the fiscal year of adoption. SAB 108 is effective for us at the end of 2006. We do not expect the adoption of SAB 108 will have a material impact on our Consolidated Financial Statements.

Use of Estimates.

The preparation of consolidated financial statements requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

Six Months Ended June 30, 2007 and 2006

(Dollars in thousands except per share data and as noted)

financial statements and the reported amounts of net sales and expenses during the reporting period. In addition, estimates and assumptions associated with the determination of the fair value of certain assets and related impairments and the determination of goodwill impairments require considerable judgment by management. Actual results could differ from the estimates and assumptions used in preparing these financial statements.

TRANSGENOMIC, INC. AND SUBSIDIARIESCash and Cash Equivalents.

Cash and cash equivalents include cash and temporary overnight investments with original maturities at acquisition of three months or less.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS - ContinuedAccounts Receivable.

Nine Months Ended SeptemberAccounts receivable are shown net of allowance for doubtful accounts. The following is a summary of activity for the allowance for doubtful accounts during the three and six months ended June 30, 20062007 and 20052006:

(Dollars in thousands except per share data)

   Three Months Ended  Six Months Ended 
   

June 30,

2007

  

June 30,

2006

  

June 30,

2007

  

June 30,

2006

 

Beginning balance

  $420  $581  $444  $615 

Charges to income

   57   (75)  33   (45)

Deductions from reserves

   (1)  (128)  (1)  (192)
                 

Ending balance

  $476  $378  $476  $378 
                 

B. DISCONTINUED OPERATIONS AND DIVESTITURES

In the fourth quarter of 2005,While payment terms are generally 30 days, the Company implementedhas also provided extended payment terms of up to 90 days in certain cases. The Company reviews accounts receivables on a plan to exit the Nucleic Acids operating segment. Accordingly, the Company now reflects the results related to this operating segment as discontinued operations for all periods presented. Expenses thatquarterly basis and adjusts its bad debt reserve accordingly.

Inventories.

Inventories are not directly identified to the Nucleic Acids operating segment or that are considered corporate overhead have not been allocated in arrivingstated at the loss from discontinued operations. Summary resultslower of operationscost or market. Cost is computed using standard costs for finished goods and average or latest actual cost for raw materials and work in process.

Equipment, Furniture and Fixtures.

Equipment, furniture and fixtures are carried at cost. Depreciation is computed by the straight-line method over the estimated useful lives of the former Nucleic Acids operating segment wererelated assets as follows:

 

   

Three Months Ended

September 30,

  

Nine Months Ended

September 30,

 
   2006  2005  2006  2005 

NET SALES

  $7  $2,043  $1,142  $3,233 

COST OF GOODS SOLD

   —     1,213   843   3,132 
                 

Gross profit

   7   830   299   101 

OPERATING EXPENSES

   172   193   605   730 
                 

INCOME (LOSS) FROM OPERATIONS

   (165)  637   (306)  (629)

OTHER INCOME

   1   —     2   11 
                 

INCOME (LOSS) BEFORE INCOME TAXES

   (164)  637   (304)  (618)

INCOME TAX

   —     —     —     —   
                 

INCOME (LOSS) FROM DISCONTINUED OPERATIONS

  $(164) $637  $(304) $(618)
                 

Leasehold improvements

3 to 10 years

Furniture and fixtures

5 to 7 years

Production equipment

5 to 7 years

Computer equipment

3 to 5 years

Research and development equipment

3 to 5 years

Demonstration equipment

3 to 5 years

During the three months ended September 30, 2006, the Company completed an evaluation of the carrying value of net assets associated with former Nucleic Acids operating segment, including an assessment of tentative offers received for the sale of the only remaining Nucleic Acids’ facility in Glasgow, Scotland (the “Facility”)Depreciation and related equipment. In conjunction with this evaluation, the Company determined that it was appropriate to further reduce the carrying value of property, plant and equipment to $2,668 resulting in an impairment charge of $437. The value assigned to property, plant and equipment consists of $2,621 related to the Glasgow Facility and $47 associated with related equipment. Furthermore, the Company also evaluated previously established liabilities related primarily to the closure of the Facility. As a result of this review, the Company reversed liabilities of $386amortization during the three months ended SeptemberJune 30, 2006. At September 30,2007 and 2006, respectively, included $218 and December 31, 2005, the Company had accrued expenses of zero and $715,$350, respectively, related to statutory payments to affected employeesdepreciation of property and other costs specifically attributable to closure ofequipment. Depreciation and amortization during the only remaining Nucleic Acids’ Facility.

The assetssix months ended June 30, 2007 and liabilities of the former Nucleic Acids operating segment were as follows:

   

September 30,

2006

  

December 31,

2005

Accounts receivable (net of allowances for bad debts of $172 and $393, respectively)

  $—    $51

Inventories

   —     86

Prepaid expenses and other current assets

   —     60
        

Current assets of discontinued operations

   —     197
        

Property, plant and equipment, net

   2,668   2,933
        

Non-current assets of discontinued operations

   2,668   2,933
        

Accounts payable

  $31  $434

Other accrued expenses

   238   863

Accrued compensation

   11   625
        

Current liabilities of discontinued operations

  $280  $1,922
        

A restructuring plan was implemented during 2004 to better align the cost structure of the former Nucleic Acids operating segment with anticipated net sales. In conjunction with this plan, the Company had accrued expenses associated with the former Nucleic Acids operating segment of $452006, respectively, included $463 and $221 at September 30, 2006 and December 31, 2005,$721, respectively, related to net rents on leaseddepreciation of property and equipment.

Goodwill

Statement of Financial Accounting Standards (“SFAS”) No. 142,Goodwill and Other Intangible Assets,provides that goodwill will not be amortized, but unoccupied facilities.will be tested for impairment annually. The future net lease payments required under these leases are approximately $34 forCompany performs this impairment analysis during the remainderfourth quarter of 2006 and $11 in 2007.each year. Impairment occurs when the carrying value is determined to be not recoverable thereby causing the fair value of the goodwill to exceed the carrying value. If impaired, the asset’s carrying value is reduced to its fair value.

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS - Continued

NineSix Months Ended SeptemberJune 30, 20062007 and 20052006

(Dollars in thousands except per share data)data and as noted)

Other Assets.

C. INVENTORIESLong-Lived Assets

Inventories consistedIn August 2001, the Financial Accounting Standards Board issued SFAS No. 144,Accounting for the Impairment or Disposal of Long-Lived Assets, (SFAS No. 144) which addresses financial accounting and reporting for the following:

   

September 30,

2006

  

December 31,

2005

Finished goods

  $1,423  $2,062

Raw materials and work in process

   841   653

Demonstration inventory

   72   275
        
  $2,336  $2,990
        

D. OTHER ASSETSimpairment or disposal of long-lived assets and supersedes SFAS No. 121, and the accounting and reporting provisions of Accounting Principles Board (APB) Opinion No. 30,Reporting the Results of Operations, for a disposal of a segment of a business. The Company periodically reviews the carrying value of its long-lived assets to assess recoverability and impairment. The Company recorded no impairments during the three and six months ended June 30, 2007 or 2006.

Finite livedOther assets include intellectual property, patents, other intangible assets, and other assets consistedlong-term assets.

Intellectual Property. Initial costs paid to license intellectual property from independent third parties are capitalized and amortized using the straight-line method over the license period. Ongoing royalties related to such licenses are expensed as incurred.

Patents. The Company capitalizes external and in-house legal costs, filing fees and other expenses associated with obtaining patents on its new discoveries and amortizes these costs using the straight-line method over the shorter of the following:legal life of the patent or its economic life, generally 17 years, beginning on the date the patent is issued.

   September 30, 2006  December 31, 2005
   Cost  

Accumulated

Amortization

  

Net Book

Value

  Cost  

Accumulated

Amortization

  

Net Book

Value

Intellectual property

  $765  $674  $91  $765  $534  $231

Patents

   675   156   519   636   135   501

Other

   517   204   313   838   496   342
                        

Total

  $1,957  $1,034  $923  $2,239  $1,165  $1,074
                        

Amortization expense forOther Intangible Assets. Identifiable intangible assets was $10with definite lives are amortized over their estimated useful lives and $222 duringtested for impairment as events or changes in circumstances indicate the three months ended September 30, 2006 and 2005, respectively, and $160 and $717 for the nine months ended September 30, 2006 and 2005, respectively. Amortization expense for intangible assets is expected to be approximately $11 for the remainder of 2006, $40 in eachcarrying amount of the next four yearsasset may be impaired.

Other Long-Term Assets. Other long-term assets consist primarily of demonstration inventory that has been at customer or prospective customer sites for greater than one year and $37 in 2011.security deposits on leased facilities. Long-term demonstration inventory is stated at the lower of cost or market.

E. DEBTStock Based Compensation.

The Company had no debt at September 30, 2006 or December 31, 2005.

In December 2003, the Company entered into a $7,500 line of credit (the “Credit Line”) with Laurus Master Fund, Ltd. (“Laurus”). The term of the Credit Line was three years carrying an interest rate of 2.0% over the prime rate or a minimum of 6.0%. The Credit Line was secured by most of the Company’s assets. In February 2004, the Company entered into a separate $2,750 convertible note with Laurus (the “Term Note”). The Term Note carried an interest rate of 2.0% over the prime rate or a minimum of 6.0%. The Company issued warrants covering 1,136,484 common shares of the Company in conjunction with the Credit Line and Term Note (collectively, the “Laurus Loans”). Principal and interest on the Laurus Loans could be converted into commonAll stock of the Company at a fixed conversion price of $1.00 per share.

Certain features of the Laurus Loans required the Companyoptions awarded to separately account for the value of certain amounts relateddate have exercise prices equal to the warrants issued and the conversion feature of the Laurus Loans. Specifically, Emerging Issues Task Force (“EITF”) No. 00-27,Application of Issue No. 98-5 to Certain Convertible Instruments, required the Company to separately value the warrants issued and the “beneficial conversion premium” related to the Laurus Loans. The values of the warrants and the beneficial conversion premium were recorded on the balance sheet as a debt discount and an increase to additional paid in capital. The debt discount recorded for these items was amortized as expense to the income statement over the terms of the Laurus Loans or as the debt was converted into common stock thereby increasing the effective interest rate on the Laurus Loans.

On March 18, 2005, the Company agreed to allow Laurus to convert $1,872 of the outstanding principal balance under the Credit Line into 3,600,000 shares of its common stock. In addition, on March 24, 2005, the Company agreed to allow Laurus to convert $650 of the outstanding principal balance of the Term Note into 1,250,000 shares of common stock. The closing market price of the Company’s common stock on the day before eachdate of these conversions was $0.58 per share. No other provisionsgrant and have ten-year contractual terms. Unvested options as of June 30, 2007 had vesting periods of three years from date of grant. None of the Credit Linestock options outstanding at June 30, 2007 are subject to performance or Term Note were modified, including the $1.00 conversion price for remaining debt. In

TRANSGENOMIC, INC. AND SUBSIDIARIESmarket-based vesting conditions.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS - Continued

Nine Months Ended September 30, 2006 and 2005

(Dollars in thousands except per share data)

conjunction with these conversionsThe Company adopted Financial Accounting Standards Board (FASB) Statement No. 123(R),Share-Based Payment (“FAS 123(R)”), on January 1, 2006. FAS 123(R) requires the Company accelerated amortization of $0.41 million of related debt premiumsto measure and discountsrecognize compensation expense for all stock-based awards made to employees and recorded a charge to interestdirectors, including stock options. Compensation expense of $1.37 million related tois based on the calculated fair value of incremental shares received by Laurus.

Interest expense consistedthe awards as measured at the grant date and is expensed ratably over the service period of the following:

   Three Months Ended  Nine Months Ended 
   September 30,
2006
  September 30,
2005
  September 30,
2006
  September 30,
2005
 

Interest paid or accrued on outstanding debt

  $—    $172  $—    $479 

Amortization of debt premiums

   —     (124)  —     (816)

Amortization of debt discounts – warrants

   —     4   —     24 

Amortization of debt discount – beneficial conversion feature

   —     81   —     725 

Fair value of incremental shares received by Laurus

   —     —     —     1,365 

Other

   7   48   7   144 
                 
  $7  $181  $7  $1,921 
                 

Contemporaneously withawards (generally the closing of a private placement of the Company’s common stock on October 31, 2005 (the “2005 Private Placement”), the Company repaid all outstanding principal and accrued interest on the Laurus Loans which have been cancelled and are no longer available to the Company.

F. COMMITMENTS AND CONTINGENCIESvesting period).

The Company is subject to a number of claims of various amounts, which arise out of the normal course of business. In the opinion of management, the disposition of pending claims will not have a material adverse effect on the Company’s financial position, results of operations or cash flows.

During the three months ended September 30, 2006, the Company was notified by one of its OEM instrument suppliers (the “Supplier”) that its primary creditor filed a petition against the Supplier requesting the appointment of a receiver. The Supplier, its shareholders and creditors, and the court-appointed receiver are evaluating alternatives, including the sale or liquidation of the Supplier. The Company has sold 16 of the Supplier’s instruments over the past three years resulting in net sales of $2,988. The Company continues to provide warranties and support for 11 of these instruments (six of which are in their initial 12-month warranty period), with such obligations expiring at various times through 2010. While agreements between the Company and the Supplier provide for the Supplier’s technologies (engineering designs, etc.) to be escrowed for the Company’s benefit, there are no assurances that the Company can continue to support these OEM customers without proprietary bioconsumables, component parts and technical assistance currently provided by the Supplier. The Company continues to coordinate with management of the Supplier, evaluate alternatives and evaluate the impact, if any, on the Company’s financial position, results of operations or cash flows.

The Company leases certain equipment, vehicles and operating facilities under non-cancellable operating leases that expire on various dates through 2014. The future minimum lease payments required under these leases are approximately $335 for the remainder of 2006, $732 in 2007, $409 in 2008, $381 in 2009, $257 in 2010 and $93 thereafter. Rent expense for continuing operations related to all operating leases for the three months ended September 30, 2006 and 2005 was approximately $260 and $238, respectively, and for the nine months ended September 30, 2006 and 2005 was $774 and $730, respectively.

At September 30, 2006 and December 31, 2005, firm commitments to vendors to purchase components used in WAVE® systems and instruments manufactured by others totaled $1,161 and $879, respectively. The Company expects to satisfy these purchase commitments during 2006 and 2007.

G. INCOME TAXES

Income tax expense during relates to income taxes in states, foreign countries and other local jurisdictions offset by refunds received. While the Company has significant net operating loss carryforwards, it is likely that Section 382

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS - Continued

Nine Months Ended September 30, 2006 and 2005

(Dollars in thousands except per share data)

(Limitation on Net Operating Loss Carryforwards and Certain Built-In Losses Following Ownership Change) of the Internal Revenue Code, and the regulations promulgated there under, will significantly limit the amount of net operating loss carry forward that the Company could utilize in any tax year. As of September 30, 2006 and December 31, 2005, deferred tax assets totaled $43,450 and $42,561, respectively, that were fully offset by valuation allowances.

H. EMPLOYEE BENEFIT PLAN

The Company maintains an employee 401(k) retirement savings plan that allows for voluntary contributions into designated investment funds by eligible employees. The Company matches the employees’ contributions at the rate of 50% on the first 6% of contributions. The Company may, at the discretion of its Board of Directors, make additional contributions on behalf of the Plan’s participants. Company contributions to the 401(k) plan were $40 and $45 for the three months ended September 30, 2006 and 2005, respectively, and $123 and $135 for the nine months ended September 30, 2006 and 2005, respectively.

I. STOCKHOLDERS’ EQUITY

Common Stock.

During the three and nine months ended September 30, 2006, the Company issued zero and 7,551 shares of common stock, respectively, under the Transgenomic, Inc. 2001 Employee Stock Purchase Plan. During the three and nine months ended September 30, 2005, the Company issued, 5,055 and 15,462 shares of common stock, respectively, under the Transgenomic, Inc. 2001 Employee Stock Purchase Plan. No additional stock will be issued under this plan as it was terminated in December 2005.

During the three and nine months ended September 30, 2005, the Company issued 4,900,000 shares of common stock in conjunction with conversions under the Laurus Loans as follows:

Date

  Price  

Shares

Issued

  

Net

Proceeds

  Facility  Applied To

January 2005

  $1.00  50,000  $50  Term Note  Principal

March 2005

  $0.52  3,600,000   1,835  Credit Note  Principal

March 2005

  $0.52  1,250,000   650  Term Note  Principal
             

Total 2005

    4,900,000  $2,535    
             

Common Stock Warrants.

No common stock warrants were issued during the nine months ended September 30, 2006 or 2005. At September 30, 2006, the Company had 8,062,577 common stock warrants outstanding.

Warrant Holder

  Issue Year  Expiration Year  Underlying Shares  Exercise Price

Various Institutional Holders(1)

  2005  2010  6,903,156  $1.20

Laurus Master Fund, Ltd.(2)

  2003  2010  200,000  $1.92

Laurus Master Fund, Ltd.(2)

  2003  2010  200,000  $2.07

Laurus Master Fund, Ltd.(2)

  2003  2010  150,000  $2.35

Laurus Master Fund, Ltd.(2)

  2004  2011  125,000  $2.57

Laurus Master Fund, Ltd.(2)

  2004  2011  400,000  $1.18

TN Capital Equities, Ltd.(2)

  2003  2008  45,918  $2.94

TN Capital Equities, Ltd.(2)

  2004  2009  15,566  $3.18

GE Capital(3)

  2002  2007  13,762  $3.27

GE Capital(3)

  2003  2008  9,175  $3.27
         

Total

      8,062,577  
         

(1)These warrants were issued in conjunction with the 2005 Private Placement.
(2)These warrants were issued in conjunction with the Laurus Loans and subsequent modifications. In conjunction with the 2005 Private Placement, the exercise prices of these warrants were adjusted according to repricing provisions contained in the original warrant agreements. While the Laurus Loans have been terminated, the warrants remain outstanding.
(3)These warrants were issued in conjunction with operating leases with GE Capital. While the leases have since been terminated, the warrants remain outstanding.

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS - Continued

Nine Months Ended September 30, 2006 and 2005

(Dollars in thousands except per share data)

J. STOCK OPTIONS

During the three months and nine months ended September 30, 2006, the Company issued 225,000 options at exercise prices of $0.68 and 15,000 options at exercise prices $1.09. The following table summarizes activity under the Company’s 2006 Equity Incentive Plan (formerly, the 1997 Stock Option Plan) during the nine months ended September 30, 2006:

   

Number of

Options

  Weighted Average
Exercise Price

Balance at January 1, 2006:

  5,571,098  $4.32

Granted

  240,000   .70

Exercised

  —     —  

Forfeited

  (86,834)  3.65
     

Balance at September 30, 2006:

  5,724,264  $4.17
     

Exercisable at September 30, 2006

  5,484,264  $4.33
     

On December 28, 2005, the Company’s Directors approved a plan to accelerate the vesting of all outstanding stock options. Aside from the acceleration of the vesting date, the terms and the conditions of the stock option award agreements governing the underlying stock option grants remained unchanged. As a result of this plan, options to purchase approximately 1,081,845 shares became immediately exercisable. All such options were out-of-the-money and, accordingly, the accelerated vesting resulted in no compensation expense since there was no intrinsic value associated with these fixed awards at the date of modification. Accelerating the vesting of these options allowed the Company to avoid recognition of compensation expense associated with these options in future periods.

During the threesix months ended SeptemberJune 30, 2007 and 2006, the Company recorded compensation expense of $3$46 and $0, respectively, within the general administrative expense related to 240,000 new option grantsthe vesting of 685,000 and $149 related to modifications to an extension of the post-termination exercisable period for 450,0000 options, from 90 days after termination to the remaining contractual term of the original option grants (the “Modified Options”).respectively during these periods. The fair value of the Modified Options wereoptions was estimated on the modificationtheir respective grant dates using the Black-Scholes option pricing model. The Black-Scholes model was used with the following assumptions: risk-free interest rates of 4.71% to 4.93%; dividend yields of zero percent; expected lives of 2 to 9 years and volatility of 89.14%. At September 30, 2006, there was $105 of unrecognized compensation expense related unvested stock options, which is expected to be recognized over a weighted-average period of nearly 5.0 years.5.08%, based on the U.S.

The following table summarizes information about options outstanding as of September 30, 2006:

   OPTIONS OUTSTANDING  OPTIONS EXCERCISABLE

Range of Exercise Prices

  Number
Outstanding
  

Weighted-Average

Remaining

Contractual Life

  

Weighted-Average

Exercise Price

  

Number

Exercisable

  Weighted-Average
Exercise Price
      (in years)         

$0.00—$1.30

  1,634,500  8.1  $1.03  1,394,500  $1.08

$1.31—$2.60

  767,333  5.9  $1.91  767,333  $1.91

$2.61—$3.90

  35,000  1.7  $2.90  35,000  $2.90

$3.91—$5.20

  2,064,700  1.3  $5.00  2,064,700  $5.00

$5.21—$7.80

  672,500  3.9  $6.15  672,500  $6.15

$7.81—$9.10

  10,000  4.6  $9.00  10,000  $9.00

$9.11—$11.70

  280,500  3.8  $9.89  280,500  $9.89

$11.71—$13.00

  259,731  3.0  $12.80  259,731  $12.80
            
  5,724,264  4.4  $4.17  5,484,264  $4.33
            

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS - Continued

NineSix Months Ended SeptemberJune 30, 20062007 and 20052006

(Dollars in thousands except per share data)data and as noted)

Treasury yield in effect at the time of grant; dividend yields of zero percent; expected lives of 2 to 10 years, based on historical exercise activity behavior; and volatility of 89.14% and 79.10% for grants issued for the three months ended March 31, 2007 and June 30, 2007, respectively, based on the historical volatility of our stock over a time that is consistent with the expected life of the option. As of June 30, 2007, there was $272 of unrecognized compensation expense related to unvested stock options, which is expected to be recognized over a weighted average period of nearly three years.

Income Taxes.

Deferred tax assets and liabilities are determined based on the differences between the financial reporting and tax basis of assets and liabilities at each balance sheet date using tax rates expected to be in effect in the year the differences are expected to reverse. Deferred tax assets are reduced by a valuation allowance to the extent that it is more likely than not that they will not be realized.

Revenue Recognition.

Revenue (referred to as “net sales”) on the sales of products is recognized in accordance with the terms of the sales arrangement. Such recognition is based on receipt of an unconditional customer order and transfer of title and risk of ownership to the customer, typically upon shipment of the product under a purchase order. The Company’s sales terms do not provide for the right of return unless the product is damaged or defective. Net sales from certain services associated with the Company’s analytical instruments, to be performed subsequent to shipment of the products, is deferred and recognized when the services are provided. Such services, mainly limited to installation and training services that are not essential to the functionality of the instruments, typically are performed in a timely manner subsequent to shipment of the instrument. The Company also enters into various service contracts that cover installed instruments. These contracts cover specific time periods and net sales associated with these contracts are deferred and recognized over the service period. At June 30, 2007 and December 31, 2006, deferred revenue mainly associated with the Company’s service contracts, included in the Company’s balance sheet in other accrued expenses, was approximately $2,047 and $1,591, respectively.

Research and Development.

Research and development costs are charged to expense when incurred.

Translation of Foreign Currency.

Financial statements of subsidiaries outside the U.S. are measured using the local currency as the functional currency. The adjustments to translate those amounts into U.S. dollars are accumulated in a separate account in stockholders’ equity and are included in accumulated other comprehensive income. Foreign currency transaction gains or losses resulting from changes in currency exchange rates are included in the determination of net income. Foreign currency transaction adjustments from continuing operations increased/decreased net income (loss) by $69 and $99 during the three and six months ended June 30, 2007, respectively, and reduced net loss by $72 and $180 during the three and six months ended June 30, 2006, respectively.

Comprehensive Income.

Accumulated other comprehensive income at June 30, 2007 and December 31, 2006 consisted of foreign currency translation adjustments, net of applicable tax of zero. The Company deems its foreign investments to be permanent in nature and does not provide for taxes on currency translation adjustments arising from converting its investments in a foreign currency to U.S. dollars.

Earnings Per Share.

Basic earnings per share is calculated based on the weighted-average number of common shares outstanding during each period. Diluted earnings per share include shares issuable upon exercise of outstanding stock options, warrants or conversion rights that have exercise or conversion prices below the market value of the Company’s common stock. Options, warrants and conversion rights pertaining to 12,175,141 and 13,538,841 shares of the Company’s common stock have been excluded from the computation of diluted earnings per share at June 30, 2007 and 2006, respectively, because the exercise or conversion price of these instruments exceeded the market price of the Company’s common stock on those dates.

TRANSGENOMIC, INC. AND SUBSIDIARIES

K. OPERATING SEGMENTNOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

Six Months Ended June 30, 2007 and 2006

(Dollars in thousands except per share data and as noted)

Recently Issued Accounting Pronouncements

In July 2006, the FASB issued Interpretation No. 48,Accounting for Uncertainty in Income Taxes(“FIN 48”). FIN 48 applies to all tax positions within the scope of Statement 109 and clarifies when and how to recognize tax benefits in the financial statements with a two-step approach of recognition and measurement. The Company adopted FIN 48 on January 1, 2007. Under FIN 48, tax benefits are recognized only for tax positions that are more likely than not to be sustained upon examination by tax authorities. The amount recognized is measured as the largest amount of benefit that is more likely than not to be realized upon ultimate settlement. Unrecognized tax benefits are tax benefits claimed in the Company’s tax returns that do not meet these recognition and measurement standards.

In September 2006, the FASB issued Statement No. 157,Fair Value Measurement (“FAS 157”). While this Statement does not require new fair value measurements, it provides guidance on applying fair value and expands required disclosures. FAS 157 is effective for the Company beginning in the first quarter of 2008. The Company is currently assessing the impact FAS 157 may have on its Consolidated Financial Statements.

In February 2007, the FASB issued Statement No. 159,The Fair Value Option for Financial Assets and Financial Liabilities (“FAS 159”). This Statement, which is expected to expand fair value measurement, permits entities to choose to measure many financial instruments and certain other items at fair value. FAS 159 will become effective for the Company beginning with the first quarter of 2008. The Company is currently assessing the impact FAS 159 may have on its Consolidated Financial Statements.

C.DISCONTINUED OPERATIONS

In the fourth quarter of 2005, the Company implemented a plan to exit its Nucleic Acids operating segment. Accordingly, the Company now reflects the results related to this operating segment as discontinued operations for all periods presented. Expenses that are not directly identified to the Nucleic Acids operating segment or that are considered corporate overhead have not been allocated in arriving at the loss from discontinued operations. Summary results of operations of the former Nucleic Acids operating segment were as follows:

   

Three Months Ended

June 30,

  

Six Months Ended

June 30,

 
   2007  2006  2007  2006 

NET SALES

  $—    $581  $—    $1,135 

COST OF GOODS SOLD

   —     463   —     843 
                 

Gross profit

   —     118   —     292 

OPERATING EXPENSES

   7   244   (66)  433 
                 

INCOME (LOSS) FROM OPERATIONS

   (7)  (126)  66   (141)

OTHER INCOME

   —     1   —     2 
                 

INCOME (LOSS) BEFORE INCOME TAXES

   (7)  (125)  66   (139)

INCOME TAX

   —     —     —     —   
                 

INCOME (LOSS) FROM DISCONTINUED OPERATIONS

  $(7) $(125) $66  $(139)
                 

Assets associated with the Nucleic Acids segment consisted principally of the Company’s facility in Glasgow, Scotland. During the six months ended June 30, 2007, the Company completed the sale of the Glasgow facility and the associated equipment for $2.9 million, net of selling expenses, which resulted in a gain of $0.1 million. The gain is reflected in the operating expenses of discontinued operations during the period.

TRANSGENOMIC, INC. AND GEOGRAPHIC INFORMATIONSUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

Six Months Ended June 30, 2007 and 2006

(Dollars in thousands except per share data and as noted)

The assets and liabilities of the former Nucleic Acids operating segment were as follows:

   June 30,
2007
  

December 31,

2006

Accounts receivable (net of allowances for doubtful accounts of $173 and $169, respectively)

  $—    $—  

Prepaid expenses and other current assets

   4   —  
        

Current assets of discontinued operations

  $4  $—  
        

Property and equipment, net

  $—    $2,773
        

Non-current assets of discontinued operations

  $—    $2,773
        

Accounts payable

  $34  $45

Other accrued expenses

   142   139
        

Current liabilities of discontinued operations

  $176  $184
        

Liabilities are related to expenses to be paid during 2007 for final closing costs of the Glasgow facility.

D.RESTRUCTURING CHARGES

The Company recorded restructuring charges totaling $624,000 and $624,000 for the three and six months ended June 30, 2007. The restructuring charges were comprised of severance totaling $364,000 and facility closure costs totaling $260,000. Restructuring charges related to three events: A restructuring plan completed in the second quarter of 2007, which resulted from the termination of 4 employees in Omaha, Nebraska; facility closure activities to close the Cramlington, England production facility and consolidate production in the Omaha, Nebraska facility; and facility closure activities to close an administrative office outside Paris, France, with those functions performed elsewhere in the organization.

E.INVENTORIES

Inventories consisted of the following:

   June 30,
2007
  

December 31,

2006

Finished goods

  $2,128  $2,146

Raw materials and work in process

   1,101   443

Demonstration inventory

   14   83
        
  $3,243  $2,672
        

F.OTHER ASSETS

Finite lived intangible assets and other assets consisted of the following:

   June 30, 2007  December 31, 2006
   Cost  

Accumulated

Amortization

  

Net Book

Value

  Cost  

Accumulated

Amortization

  

Net Book

Value

Intellectual property

  $865  $692  $173  $765  $677  $88

Patents

   643   177   466   676   155   521

Other

   302   208   94   705   461   244
                        

Total

  $1,810  $1,077  $733  $2,146  $1,293  $853
                        

Amortization expense for intangible assets was $24 and $133 during the three months ended June 30, 2007 and 2006, respectively, and $46 and $150 during the six months ended June 30, 2007 and 2006, respectively. Amortization expense for intangible assets is expected to be approximately $46 for the remainder of 2007, $86 in 2008, $75 in 2009, $50 in 2010, $38 in 2011, and $32 in 2012 and 2013.

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

Six Months Ended June 30, 2007 and 2006

(Dollars in thousands except per share data and as noted)

G.COMMITMENTS AND CONTINGENCIES

The Company is subject to a number of claims of various amounts, which arise out of the normal course of business. In the opinion of management, the disposition of pending claims will not have a material adverse effect on the Company’s financial position, results of operations or cash flows.

The Company leases certain equipment, vehicles and operating facilities under non-cancellable operating leases that expire on various dates through 2014. The future minimum lease payments required under these leases are approximately $541 for the remainder of 2007, $863 in 2008, $770 in 2009, $657 in 2010, $500 in 2011, $226 in 2012, and $98 thereafter. Rent expense for continuing operations related all to operating leases for the three months ended June 30, 2007 and 2006 was approximately $246 and $303, respectively, and for the six months ended June 30, 2007 and 2006 was approximately $527 and $596, respectively.

At June 30, 2007, firm commitments to vendors to purchase components used in WAVE Systems and instruments manufactured by others totaled $1,254. The Company expects to satisfy these purchase commitments during 2007.

H.INCOME TAXES

In July 2006, the FASB issued Interpretation No. 48,Accounting for Uncertainty in Income Taxes(“FIN 48”). FIN 48 applies to all tax positions within the scope of Statement 109 and clarifies when and how to recognize tax benefits in the financial statements with a two-step approach of recognition and measurement. The Company adopted FIN 48 on January 1, 2007. Under FIN 48, tax benefits are recognized only for tax positions that are more likely than not to be sustained upon examination by tax authorities. The amount recognized is measured as the largest amount of benefit that is more than likely not to be realized upon ultimate settlement. Unrecognized tax benefits are tax benefits claimed in the Company’s tax returns that do not meet these recognition and measurement standards.

Upon adoption of FIN 48 on January 1, 2007, the Company recognized a $129 increase in the liability for unrecognized tax benefits. This increase in the liability was offset by an increase to the January 1, 2007 balance in the accumulated deficit. The gross amount of unrecognized tax benefits as of the date of adoption was $129, all of which would affect the effective tax rate if recognized. Included in this amount is an aggregate of $72 of interest and penalties. The Company’s policy is to recognize interest and penalties directly related to income taxes as part of income tax expense.

The Company files income tax returns in the U.S. federal jurisdiction, various U.S. state jurisdictions and various foreign jurisdictions. The Company has statutes of limitation open for Federal income tax returns related to tax years 2004 through 2006. The Company has state income tax returns subject to examination primarily for tax years 2003 through 2006. Open tax years related to foreign jurisdictions remain subject to examination. The Company’s primary foreign jurisdiction is the United Kingdom which has open tax years for 2005 through 2006. The Company is not currently under examination in any jurisdiction.

During the three and six months ended June 30, 2007, there were no material changes to the liability for uncertain tax positions.

I.EMPLOYEE BENEFIT PLAN

The Company maintains an employee 401(k) retirement savings plan that allows for voluntary contributions into designated investment funds by eligible employees. The Company matches the employees’ contributions at the rate of 50% on the first 6% of contributions. The Company may, at the discretion of its Board of Directors, make additional contributions on behalf of the Plan’s participants. Company contributions to the 401(k) plan were $39 and $41 for the three months ended June 30, 2007 and 2006, respectively, and $81 and $83 for the six months ended June 30, 2007 and 2006, respectively.

J.STOCKHOLDERS’ EQUITY

Common Stock Warrants.

No common stock warrants were issued during the three and six months ended June 30, 2007 or 2006. At June 30, 2007, the Company had 8,062,577 common stock warrants outstanding.

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

Six Months Ended June 30, 2007 and 2006

(Dollars in thousands except per share data and as noted)

Warrant Holder

  Issue Year  Expiration Year  Underlying Shares  Exercise Price

Various Institutional Holders(1)

  2005  2010  6,903,156  $1.20

Laurus Master Fund, Ltd.(2)

  2003  2010  200,000  $1.92

Laurus Master Fund, Ltd.(2)

  2003  2010  200,000  $2.07

Laurus Master Fund, Ltd.(2)

  2003  2010  150,000  $2.35

Laurus Master Fund, Ltd.(2)

  2004  2011  125,000  $2.57

Laurus Master Fund, Ltd.(2)

  2004  2011  400,000  $1.18

TN Capital Equities, Ltd.(2)

  2003  2008  45,918  $2.94

TN Capital Equities, Ltd.(2)

  2004  2009  15,566  $3.18

GE Capital(3)

  2002  2007  13,762  $3.27

GE Capital(3)

  2003  2008  9,175  $3.27
         

Total

      8,062,577  
         

(1)These warrants were issued in conjunction with a private placement of common stock in October 2005 (the “2005 Private Placement”).
(2)These warrants were issued in conjunction with two loans that had been made by Laurus Master Fund, Ltd. to the Company (the “Laurus Loans”), and subsequent modifications of these loans. In conjunction with the 2005 Private Placement, the exercise prices of these warrants were adjusted according to repricing provisions contained in the original warrant agreements. While the Laurus Loans have been terminated, the warrants remain outstanding.
(3)These warrants were issued in conjunction with operating leases with GE Capital. While the leases have since been terminated, the warrants remain outstanding.

K.STOCK OPTIONS

The following table summarizes stock option activity during the six months ended June 30, 2007:

   

Number of

Options

  

Weighted Average

Exercise Price

Balance at January 1, 2007

  5,467,664  $4.07

Granted

  345,000   0.73

Exercised

  —     —  

Forfeited

  (1,700,100)  4.23
     

Balance at June 30, 2007

  4,112,564  $3.72
     

Exercisable at June 30, 2007

  3,442,564  $4.32
     

During the six months ended June 30, 2007, the Company granted 345,000 stock options at a weighted average exercise price of $0.73 under its 2006 Equity Incentive Plan (formerly, the 1997 Stock Option Plan). The weighted average grant date fair value per share of options granted during the six months ended June 30, 2007 was $0.56.

During the six months ended June 30, 2007 and 2006, the Company recorded compensation expense of $46 and $0, respectively, within the general administrative expense related to the vesting of 685,000 and 0 options, respectively during these periods. The fair value of the options was estimated on their respective grant dates using the Black-Scholes option pricing model. The Black-Scholes model was used with the following assumptions: risk-free interest rates of 4.71% to 5.08%, based on the U.S. Treasury yield in effect at the time of grant; dividend yields of zero percent; expected lives of 2 to 10 years, based on historical exercise activity behavior; and volatility of 89.14% and 79.10% for grants issued for the three months ended March 31, 2007 and June 30, 2007, respectively, based on the historical volatility of our stock over a time that is consistent with the expected life of the option. As of June 30, 2007, there was $272 of unrecognized compensation expense related to unvested stock options, which is expected to be recognized over a weighted average period of nearly three years.

TRANSGENOMIC, INC. AND SUBSIDIARIES

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

Six Months Ended June 30, 2007 and 2006

(Dollars in thousands except per share data and as noted)

L.OPERATING SEGMENT AND GEOGRAPHIC INFORMATION

The Company has one reportable operating segment. Although net sales are analyzed by type, net financial results are analyzed as one segment due to the integrated nature of the products. Net sales by product were as follows:

 

  

Three Months Ended

September 30,

  

Nine Months Ended

September 30,

  Three Months Ended  Six Months Ended
  2006  2005  2006  2005  

June 30,

2007

  

June 30,

2006

  

June 30,

2007

  

June 30,

2006

Bioinstruments

  $2,510  $3,745  $10,294  $11,343  $3,383  $3,743  $6,006  $7,784

Bioconsumables

   2,100   2,210   6,640   6,978   2,218   2,296   4,448   4,540

Discovery Services

   309   708   671   2,159   671   150   1,040   362
                        
  $4,919  $6,663  $17,605  $20,480  $6,272  $6,189  $11,494  $12,686
                        

Net cost of goods sold was as follows:

   Three Months Ended  Six Months Ended
   

June 30,

2007

  

June 30,

2006

  

June 30,

2007

  

June 30,

2006

Bioinstruments

  $1,368  $1,492  $2,359  $3,252

Bioconsumables

   1,013   1,222   2,078   2,495

Discovery Services

   478   426   936   907
                
  $2,859  $3,140  $5,373  $6,654
                

Net sales by geographic region were as follows:

 

  

Three Months Ended

September 30,

  

Nine Months Ended

September 30,

  Three Months Ended  Six Months Ended
  2006  2005  2006  2005  

June 30,

2007

  

June 30,

2006

  

June 30,

2007

  

June 30,

2006

United States

  $1,712  $1,925  $4,996  $5,733  $2,365  $1,454  $3,658  $3,284

Europe

   2,870   3,466   10,652   11,514   3,411   4,042   6,650   7,782

Pacific Rim

   165   664   1,075   1,997   326   492   641   910

Other

   172   608   882   1,236   170   201   545   710
                        
  $4,919  $6,663  $17,605  $20,480  $6,272  $6,189  $11,494  $12,686
                        

No customer accounted for more than 10% of consolidated net sales during the three and ninesix months ended SeptemberJune 30, 2006. Sales to a large pharmaceutical company totaled $42007 and $599 during the three months ended September 30, 2006 and 2005, respectively, and represented 0% and 9%, respectively, of consolidated net sales. Sales to the same company totaled $105 and $2,009 during the nine months ended September 30, 2006 and 2005, respectively, and represented 0.5% and 10%, respectively, of consolidated net sales. Sales to this customer are governed by a non-binding master services agreement dated August 22, 2002. Accordingly, the amount of sales to this customer is subject to change.2006.

Substantially, all the Company’s long-lived assets are within the United States.

Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations

Item 2.Management’s Discussion and Analysis of Financial Condition and Results of Operations

Overview

We develop, assemble, manufacture and market versatile products for the synthesis, purification and analysis of nucleic acids used in life sciences industry for research focused on molecular genetics and diagnostics. We also provide analytical services to the medical research, clinical and pharmaceutical markets for use in genetic variation analysis. Products and services are sold through a direct sales force in the United States and throughout much of Western Europe. For the rest of the world, products and services are sold through more than 2535 dealers and distributors located in those local markets. Net sales are categorized as bioinstruments, bioconsumables and discovery services.

 

Bioinstruments. Our flagship product is the WAVE® system which has broad applicability to genetic variation detection in both molecular genetic research and molecular diagnostics. There was a world-wide installed base of over 1,300 WAVE® systems as of September 30, 2006. We also sell a number of complementary equipment platforms manufactured by others (“OEM Instruments”). Service contracts to maintain installed systems are sold and supported by technical support personnel.

Bioinstruments. Our flagship product is the WAVE System which has broad applicability to genetic variation detection in both molecular genetic research and molecular diagnostics. There is a worldwide installed base of over 1,375 WAVE Systems as of June 30, 2007. We also sell a number of complementary equipment platforms manufactured by others (“OEM Instruments”). Service contracts to maintain installed systems are sold and supported by technical support personnel.

Bioconsumables. The installed WAVE® base generates a demand for consumables that are required for the system’s continued operation. We develop, manufacture and sell these products. In addition, we manufacture and sell consumable products that can be used on a number of equipment platforms manufactured by others. These products include SURVEYOR Nuclease and a range of HPLC separation columns.

 

Bioconsumables. The installed WAVE base and some third-party installed platforms generate a demand for consumables that are required for the system’s continued operation. We develop, manufacture and sell these products. In addition, we manufacture and sell consumable products that can be used on a number of equipment platforms manufactured by others. These products include SURVEYOR Nuclease and a range of HPLC separation columns.

Discovery Services. We provide various genetic laboratory services through a contract research lab in Gaithersburg, Maryland and a second laboratory in Omaha, Nebraska thatNebraska. The lab in Omaha operates in a Good Laboratory Practices (“GLP”) compliant environment and is certified under the Clinical Laboratory Improvement Amendment (“CLIA”). The services provided by our labs primarily include (1) genomic researchbiomarker analysis services to pharmaceutical and biopharmaceutical companies to support preclinical and clinical development of targeted therapeutics;therapeutics, and (2) molecular-based medical testing services for hematology, oncology and certain inherited diseases for physicians and third-party laboratories.

Historically, we operated a segment (the “Nucleic Acids operating segment”) that developed, manufactured and marketed chemical building blocks for nucleic acid synthesis to biotechnology, pharmaceutical and oligonucleotide synthesis companies and research institutions throughout the world. In the fourth quarter of 2005, we implemented a plan to exit this operating segment. Accordingly, results of this operating segment are reflected as discontinued operations for all periods presented.presented in this filing. In the first quarter of 2007, the Company completed the sale of the remaining assets associated with the segment.

Executive Summary

We have experienced declining net sales and recurring net losses that have resulted in an accumulated deficit at September 30, 2006 of $124.48 million. To respond to changes in the overall business climate for our products, our liquidity position and capital structure, we have taken a number of steps including the exit from our former Nucleic Acids operating segment and implementation of cost reduction initiatives. Additionally, we are performing an extensive evaluation of our strategy that includes a detailed assessment of our technologies, products, markets, personnel, opportunities and risks. We are also evaluating strategic alternatives (with a third-party advisor) that include but are not limited to 1) the sale of all or portions of the continuing business or related assets; 2) the acquisition of complementary businesses or assets; 3) a merger; and/or 4) other complementary business partnerships and collaborations.

2006 Results

Net sales for the three and nine months ended SeptemberJune 30, 2006 were down 26% and 14%2007 increased by 1%, respectively, compared to the same periodsperiod in 2005.2006. The shortfallsincrease is all attributable to our Discovery Services products. Net sales from bioinstruments were in all net sales categories, but primarily in bioinstruments and discovery services. Bioinstrumentsdown 10%. Fewer WAVE sales were the cause of this decrease. Net sales from bioconsumables were down dueby 3%. Net sales from Discovery Services grew more than 300%, or $521,000, compared to lowerthe same quarter in 2006. The majority of the increase was related to the CLIA laboratory services. We also had strong sequential quarter over quarter growth in sales of WAVE® instruments offset by increasedCLIA laboratory services of 82%, or $300,000 in net salessales. We continue to see improvement in gross margins. Our gross profit margins improved from 49% in the second quarter of 2006 to 54% in the current quarter ended June 30, 2007. The largest contributor to this increase is our Discovery Services product upgrades, service contractsline which went from a negative gross profit in both the second quarter of 2006 and salesthe first quarter of OEM Instruments. Discovery services net sales were down from2007 to a positive gross profit margin of 29% in the expirationquarter ended June 30, 2007. Overall operating expenses included $624,000 of contracts withrestructuring charges, primarily related to closings in France and the United Kingdom. Net profit was $226,000 for the second quarter ended June 30, 2007. This included two non-recurring items. First, we completed the sale of an investment in equity securities realizing a large pharmaceutical company in 2005.

Despite reduced sales, losses from operationsgain of $937,500. The second item noted above was the $624,000 of restructuring charges. As of the end of the second quarter ended June 30, 2007, we had cash and net losses,cash equivalents of $7.9 million and believe we will have operated at closesufficient liquidity to cash-flow break-even during 2006 as a result better working capital management, including better collections of accounts receivable and more efficient management of inventory. Net cash used formeet our operating activities duringneeds throughout the three months ended September 30, 2006 was $0.19 million where as net cash flows generated from operating activities during the nine months ended September 30, 2006 was $0.48 million.year.

Outlook

TimingWe continue to work toward our objective of the demand for our products, particularly our flagship WAVE® systems, has been difficult to predict due largely to ongoing changes in the marketplace and the funding arrangements of our customers. Because our net sales are largely dependent upon sales of a limited number of products, including WAVE® systems, and our cost structure is largely

fixed, historical results have been somewhat sporadic. For these reasons, it is not our practice to provide prospective financial guidance related specifically to net sales, costs, net income (loss) or cash flows. However, our financial objectives are to generategenerating income from continuing operations and positive cash flows from continuing operations. To accomplish these goals, we must generate sequential growth in net sales convert manufacturing expenses from fixed to variable costs and continue to better control manufacturing and other operating expenses. These objectivesSales of bioinstruments, including both our WAVE System and instruments we

sell for other manufacturers, continue to be affected by competition from other technologies. In addition, ongoing changes in the marketplace and the funding arrangements of our customers have led to sporadic sales in some markets. We continue to work to develop new applications for our WAVE System in an attempt to expand its market and sales. Sales of our OEM instruments continue to be a priority. We are more thoroughly discussedalso focusing increased efforts to expand our Discovery Services sales. In particular, the growth in our Annual Report on Form 10-K forCLIA laboratory services has been promising and we believe we will continue to see ongoing growth from this business. We recently announced further cost reduction initiatives, including the fiscal year ended December 31, 2005.closing of facilities in Europe. While the effects of these efforts have not been realized in the first half of 2007, we expect to see a more noticeable impact in the second half of the year.

Results of Continuing Operations

Three Months Ended SeptemberJune 30, 20062007 and 20052006

Net Sales. Net sales consisted of the following (dollars in thousands):

 

  

Three Months Ended

September 30,

  Change   Three Months Ended
June 30,
  Change 
  2006  2005  $ %   2007  2006  $ % 

Bioinstruments

  $2,510  $3,745  $(1,235) (33)%  $3,383  $3,743  $(360) (10)%

Bioconsumables

   2,100   2,210   (110) (5)%   2,218   2,296   (78) (3)%

Discovery Services

   309   708   (399) (56)%   671   150   521  347%
                      

Net sales

  $4,919  $6,663  $(1,744) (26)%  $6,272  $6,189  $83  1%
                      

NineThe bioinstrument net sales decrease of 10% was due to fewer WAVE® systems Systems being sold. Sixteen WAVE Systems were sold during the three months ended SeptemberJune 30, 20062007, compared to 2824 during the same period of 2005.2006. WAVE sales in each period include sales of refurbished WAVEs. This decrease resulted from lower demand in all major geographic markets and among both research and diagnostic users particularlyprimarily in our largest markets throughout Western Europe. The sale of OEM instruments increased from 2 in the three months ended June 30, 2006 to 3 in the same period in 2007. There are significant competitive challenges from traditional (i.e. sequencing) and evolving technologies. Even so, we believe that there are increasing opportunities for our WAVE® systems in emerging markets and for novel applications. As a result, we are redirecting our distribution network to focus on these opportunities. We are also selling refurbished WAVE systems in order to access customers that may not be able to afford new systems. The decrease in WAVE® system sales was partially offset by increased net sales from product upgrades, service contracts and OEM Instruments.

Net sales of consumables related to our WAVE® systems fell during the three months ended September 30, 2006 compared Systems and other third-party instruments were down slightly year over year, primarily related to the same period of 2005 due primarily to competitive pricing changes principallyour separations product. The largest growth was in Europe, and to a lesser extent, the impact of foreign currency fluctuations.

The decrease inour discovery services net salessales. The 347% increase was primarilyall attributable to the expiration of certain research contracts with a large pharmaceutical company in 2005 that was partially offset by increased net sales from research projects with the National Institute of Health and services provided by our CLIA lab. We continue to seek opportunities to provide genetic variation discovery and analysis services to pharmaceutical and other customers and believe that these services provide us a significant opportunity to expand net sales in the future.laboratory services.

Costs of Goods Sold.Costs of goods sold include material costs for the products that we sell and substantially all other costs associated with our manufacturing facilities (primarily personnel costs, rent and depreciation). It also includes direct costs (primarily personnel costs, rent, supplies and supplies)depreciation) associated with our discovery services operations. Cost of goods sold consisted of the following (dollars in thousands):

 

  

Three Months Ended

September 30,

  Change   

Three Months Ended

June 30,

  Change 
  2006  2005  $ %   2007  2006  $ % 

Bioinstruments

  $1,046  $1,818  $(772) (42)%  $1,368  $1,492  $(124) (8)%

Bioconsumables

   1,135   1,119   16  1%   1,013   1,222   (209) (17)%

Discovery Services

   426   611   (185) (30)%   478   426   52  12%
                      

Cost of goods sold

  $2,607  $3,548  $(941) (27)%  $2,859  $3,140  $(281) (9)%
                      

Gross profit was $2.31$3.4 million or 47%54% of total net sales during the three months ended SeptemberJune 30, 20062007, compared to $3.12$3.0 million and 47%or 49% during the same period of 2005.2006. Although net sales declined, gross profits as percentage of net sales remained the sameincreased due to lower consumable material and manufacturing costs for refurbished WAVE® systems and increasedalso due to the leverage of the discovery services costs. Some of the decrease in manufacturing costs was due to a shifting of personnel to research and development efforts. The Company continues to have a large fixed expense base outside of direct material costs. Discovery services costs have a large fixed component, so increases in net sales from product upgrades and service contracts which generates largerdrive gross profits.profit improvement.

Selling, General and Administrative Expenses. Selling, general and administrative expenses primarily includeconsist of personnel costs, marketing, travel and entertainment costs, professional fees, and facility costs. These costs totaled $3.31$3.1 million during the three months ended SeptemberJune 30, 20062007, compared to $2.69$2.8 million during the same period of 2005,2006, an

increase of $0.62$0.3 million or 23%11%. This increase resultedwas primarily from increase compensation expense due to increased salescompensation expense associated with personnel reassigned from Nucleic Acids production. These expenses are consistent with the third and marketing personnel, stock-based compensation and bad debt provisions. Additionally, foreign currency transaction adjustments increased operatingfourth quarters of 2006 which we believe is a better comparison as all three quarters are comparable with no realignment of expenses by approximately $0.08 million during the three months ended September 30, 2006 compared to the same period of 2005 when foreign currency transaction adjustments decreased operating expenses by approximately $0.14 million.between areas.

Research and Development Expenses. Research and development expenses primarily include personnel costs, outside services, supplies, and facility costs and are expensed in the period in which they are incurred. These costs remained flat and totaled $0.59$0.5 million during the three months ended SeptemberJune 30, 20062007, compared to $0.51$0.5 million during the same period of 2005, an increase of $0.08 million, primarily from increased personnel.2006.

Research and development expenses totaled 12%8% and 8%9% of net sales during the three months ended SeptemberJune 30, 2007 and 2006, respectively.

Restructuring Charges. Restructuring charges consist of costs related to a reduction in force at our Omaha, Nebraska facility, ongoing activities to close a production facility in Cramlington, England, and 2005, respectively. We expectongoing activities to continue to invest approximately 10%close an administrative office outside of our net sales in research and development activities. Research and development costs are expensed in the year in which they are incurred.Paris, France.

Other Income (Expense). Other income during the three months ended SeptemberJune 30, 20062007 was $1.0 million as compared to less than $0.1 million for the three months ended June 30, 2006. The increase was attributable to the sale of $0.06 millionan investment in equity securities. On May 10, 2007, the Company sold 250,000 shares of stock in Pinnacle Pharmaceuticals, Inc. at a price of $3.75 per share. Gross proceeds realized from the sale were $937,500 which resulted in a gain of $937,500 and is reflected in other income during the period. Remaining other income consisted primarily of interest income from cash and cash equivalents invested in overnight instruments. Other expense during the three months ended September 30, 2005 of $0.18 million consisted primarily of interest expense.

Interest expense during the three months ended September 30, 2006 and 2005 consisted of the following (in thousands):

   Three months Ended
September 30,
 
   2006  2005 

Interest paid or accrued on outstanding debt

  $—    $172 

Amortization of debt premiums

   —     (124)

Amortization of debt discounts – warrants

   —     4 

Amortization of debt discount – beneficial conversion feature

   —     81 

Other

   7   48 
         
  $7  $181 
         

Interest expense during the three months ended September 30, 2005 was incurred in connection with a $7.50 million credit line and a $2.75 million term loan from Laurus Master Fund, Ltd. (the “Laurus Loans”). Contemporaneously with the closing of a private placement of our common stock on October 31, 2005, we repaid all outstanding principal and accrued interest on the Laurus Loans. Accordingly, we had no interest expense associated with the Laurs loans during the third quarter of 2006.

Income Tax Expense.In July 2006, the FASB issued Interpretation (“FIN”) No. 48,Accounting for Uncertainty in Income Taxes. FIN 48 applies to all tax expense relatespositions within the scope of Statement 109 and clarifies when and how to income taxesrecognize tax benefits in states, foreign countriesthe financial statements with a two-step approach of recognition and other local jurisdictions offsetmeasurement. We adopted FIN 48 on January 1, 2007. Under FIN 48, tax benefits are recognized only for tax positions that are more likely than not to be sustained upon examination by refunds received. While we have significant net operating loss carryforwards, ittax authorities. The amount recognized is likely that Section 382 (Limitation on Net Operating Loss Carryforwards and Certain Built-In Losses Following Ownership Change) ofmeasured as the Internal Revenue Code, and the regulations promulgated there under, will significantly limit thelargest amount of net operating loss carry forwardbenefit that we could utilizeis more likely than not to be realized upon ultimate settlement. Unrecognized tax benefits are tax benefits claimed in anyour tax year. As of September 30, 2006returns that do not meet these recognition and December 31, 2005, deferred tax assets totaled $43,450 and $42,561, respectively, that were fully offset by valuation allowances.measurement standards.

NineSix Months Ended SeptemberJune 30, 20062007 and 20052006

Net Sales. Net sales consisted of the following (dollars in thousands):

 

  

Nine Months Ended

September 30,

  Change   

Six Months Ended

June 30,

  Change 
  2006  2005  $ %   2007  2006  $ % 

Bioinstruments

  $10,294  $11,343  $(1,049) (9)%  $6,006  $7,784  $(1,778) (23)%

Bioconsumables

   6,640   6,978   (338) (5)%   4,448   4,540   (92) (2)%

Discovery Services

   671   2,159   (1,488) (69)%   1,040   362   678  187%
                      

Net sales

  $17,605  $20,480  $(2,875) (14)%  $11,494  $12,686  $(1,192) (9)%
                      

We sold a totalThe bioinstrument net sales decrease of 5623% was due to fewer WAVE® systems Systems and OEM instruments being sold. Thirty WAVE Systems were sold during the ninesix months ended SeptemberJune 30, 20062007, compared to 7647 during the same period of 2005.2006. There were 5 OEM instruments sold during the six months ended June 30, 2007 compared to 8 during the same period in 2006. WAVE sales in each period include sales of refurbished WAVEs. This decrease resulted from lower demand in all major geographic markets and among both research and diagnostic users, particularly in our largest markets throughout Western Europe. There are significant competitive challenges from traditional (i.e. sequencing) and evolving technologies. Even so, we believe that there are increasing opportunities for our WAVE® systems in emerging markets and for novel applications. As a result, we are redirecting our

distribution network to focus on these opportunities. We are also selling refurbished WAVE systems in order to access customers that may not be able to afford new systems. The decrease in WAVE® system sales was partially offset by increased net sales from product upgrades, service contracts and OEM Instruments.

Net sales of consumables related to our WAVE® systems fell during the nine months ended September 30, 2006 compared to the same period Systems and other third-party instruments were relatively flat year over year. The largest growth, an increase of 2005 due primarily to competitive pricing changes principally in Europe and to a lesser extent the impact of foreign currency fluctuations.

The decrease187%, was in discovery services, net sales was primarilyand all attributable to the expiration of certain research contracts with a large pharmaceutical company in 2005. The loss of these net sales was partially offset by increased net sales from research projects with the National Institute of Health and services provided by our CLIA lab. We continue to seek opportunities to provide genetic variation discovery and analysis services to pharmaceutical and other customers and believe that these services provide us a significant opportunity to expand net sales in the future.laboratory services.

Costs of Goods Sold.Costs of goods sold include material costs for the products that we sell and substantially all other costs associated with our manufacturing facilities (primarily personnel costs, rent and depreciation). It also includes direct costs (primarily personnel costs, rent, supplies and supplies)depreciation) associated with our discovery services operations. Cost of goods sold consisted of the following (dollars in thousands):

 

  

Nine Months Ended

September 30,

  Change   

Six Months Ended

June 30,

  Change 
  2006  2005  $ %   2007  2006  $ % 

Bioinstruments

  $4,297  $5,396  $(1,099) (20)%  $2,359  $3,252  $(893) (27)%

Bioconsumables

   3,630   3,340   290  9%   2,078   2,495   (417) (17)%

Discovery Services

   1,334   1,744   (410) (24)%   936   907   29  3%
                      

Cost of goods sold

  $9,261  $10,480  $(1,219) (12)%  $5,373  $6,654  $(1,281) (19)%
                      

Gross profit was $8.34$6.1 million or 47%53% of total net sales during the ninesix months ended SeptemberJune 30, 20062007 compared to $10.00$6.0 million and 49%or 48% during the same period of 2005. The decrease in2006. Although net sales declined, gross profitprofits as a percentpercentage of net sales is largely attributableincreased due to lower costs for refurbished WAVE Systems, the mix of instruments sold, lower consumable material and manufacturing costs and the leverage related to the change in product mix anddiscovery services net sales. Some of the decrease in manufacturing costs was due to a shifting of personnel to research and development efforts. The Company continues to have a large fixed expense base outside of direct material costs. Discovery Services costs have a large fixed component, so increases in net sales from discovery services and bioconsumables.drive gross profit improvement.

Selling, General and Administrative Expenses. Selling, general and administrative expenses primarily includeconsist of personnel costs, marketing, travel and entertainment costs, professional fees, and facility costs. These costs totaled $8.83$6.0 million during the ninesix months ended SeptemberJune 30, 20062007, compared to $9.28$5.5 million during the same period of 2005, a decrease2006, an increase of $0.45$0.5 million or 5%9%. This decrease resultedincrease was primarily due to increased compensation expense associated with personnel reassigned from foreign currency transaction adjustments , offset by increased stock-based compensation. Foreign currency transaction adjustments reduced operatingNucleic Acids production. These expenses by approximately $0.10 million duringare consistent with the nine months ended September 30,third and fourth quarters of 2006 compared to the same periodwhich we believe is a better comparison as all three quarters are comparable with no realignment of 2005 when foreign currency transaction adjustments increased operating expenses by approximately $0.32 million.between areas.

Research and Development Expenses. Research and development expenses primarily include personnel costs, outside services, supplies, and facility costs and are expensed in the period in which they are incurred. These costs totaled $1.72$1.6 million during the ninesix months ended SeptemberJune 30, 20062007, compared to $1.70$1.1 million during the same period of 2005,2006, an increase of $0.02 million. $0.5 million, primarily from collaboration expense on new WAVE applications, increased compensation costs associated with personnel reassigned from Nucleic Acid production and patent costs for discovery services.

Research and development expenses totaled 10%13% and 8%9% of net sales during the ninesix months ended SeptemberJune 30, 2007 and 2006, respectively.

Restructuring Charges. Restructuring charges consist of costs related to a reduction in force at our Omaha, Nebraska facility, ongoing activities to close a production facility in Cramlington, England, and 2005, respectively. We expectongoing activities to continue to invest approximately 10%close an administrative office outside of our net sales in research and development activities.Paris, France.

Other Income (Expense). Other income during the ninesix months ended SeptemberJune 30, 2007 and 2006 was $1.1 million and $0.1 million, respectively. The increase was attributable to the sale of $0.15 millionan investment in equity securities. On May 10, 2007, the Company sold 250,000 shares of stock in Pinnacle Pharmaceuticals, Inc. at a price of $3.75 per share. Gross proceeds realized from the sale were $937,500 which resulted in a gain of $937,500 and is reflected in other income during the period. Remaining other income consisted primarily of interest income from cash and cash equivalents invested in overnight instruments. Other expense during the nine months ended September 30, 2005 of $1.91 million consisted primarily of interest expense.

Interest expense during the nine months ended September 30, 2006 and 2005 consisted of the following (in thousands):

   Nine months Ended
September 30,
 
   2006  2005 

Interest paid or accrued on outstanding debt

  $—    $479 

Amortization of debt premiums

   —     (816)

Amortization of debt discounts – warrants

   —     24 

Amortization of debt discount – beneficial conversion feature

   —     725 

Valuation charge associated with March 2005 conversions

   —     1,365 

Other

   7   144 
         
  $7  $1,921 
         

Interest expense during the nine months ended September 30, 2005 was incurred in connection with a $7.50 million credit line and a $2.75 million term loan from Laurus Master Fund, Ltd. (the “Laurus Loans”). Contemporaneously with the closing of a private placement of our common stock on October 31, 2005, we repaid all outstanding principal and accrued interest on the Laurus Loans. Accordingly, we had no interest expense, associated with the Laurus loans, during the nine months ended September 30, 2006.

Income Tax Expense.In July 2006, the FASB issued Interpretation (“FIN”) No. 48,Accounting for Uncertainty in Income Taxes. FIN 48 applies to all tax expense relatespositions within the scope of Statement 109 and clarifies when and how to income taxesrecognize tax benefits in states, foreign countriesthe financial statements with a two-step approach of recognition and other local jurisdictions offsetmeasurement. We adopted FIN 48 on January 1, 2007. Under FIN 48, tax benefits are recognized only for tax positions that are more likely than not to be sustained upon examination by refunds received. While we have significant net operating loss carryforwards, ittax authorities. The amount recognized is likely that Section 382 (Limitation on Net Operating Loss Carryforwards and Certain Built-In Losses Following Ownership Change) ofmeasured as the Internal Revenue Code, and the regulations promulgated there under, will significantly limit thelargest amount of net operating loss carry forwardbenefit that we could utilizeis more likely than not to be realized upon ultimate settlement. Unrecognized tax benefits are tax benefits claimed in anyour tax year. As of September 30, 2006returns that do not meet these recognition and December 31, 2005, deferred tax assets totaled $43,450 and $42,561, respectively, that were fully offset by valuation allowances.measurement standards.

Results of Discontinued Operations

Three Months Ended SeptemberJune 30, 20062007 and 2006

In the fourth quarter of 2005, we implemented a plan to exit the Nucleic Acids operating segment. Accordingly, we now reflect the related results as discontinued operations for all periods presented. Expenses that are not directly identified to the Nucleic Acids operating segment or that are considered corporate overhead have not been allocated in arriving at the loss from discontinued operations. Summary results of operations of the former Nucleic Acids operating segment were as follows (in thousands):

   Three Months Ended
June 30,
 
   2007  2006 

NET SALES

  $—    $581 

COST OF GOODS SOLD

   —     463 
         

Gross profit

   —     118 

OPERATING EXPENSES

   7   244 
         

INCOME (LOSS) FROM OPERATIONS

   (7)  (126)

OTHER INCOME

   —     1 
         

INCOME (LOSS) BEFORE INCOME TAXES

   (7)  (125)

INCOME TAX

   —     —   
         

INCOME (LOSS) FROM DISCONTINUED OPERATIONS

  $(7) $(125)
         

Six Months Ended June 30, 2007 and 2006

In the fourth quarter of 2005, we implemented a plan to exit the Nucleic Acids operating segment. Accordingly, we now reflect the related results as discontinued operations for all periods presented. Expenses that are not directly identified to the Nucleic Acids operating segment or that are considered corporate overhead have not been allocated in arriving at the loss from discontinued operations. Summary results of operations of the former Nucleic Acids operating segment were as follows (in thousands):

 

  

Three Months Ended

September 30,

  Six Months Ended
June 30,
 
  2006 2005  2007 2006 

NET SALES

  $7  $2,043  $—    $1,135 

COST OF GOODS SOLD

   —     1,213   —     843 
             

Gross profit

   7   830   —     292 

OPERATING EXPENSES

   172   193   (66)  433 
             

INCOME (LOSS) FROM OPERATIONS

   (165)  637   66   (141)

OTHER INCOME

   1   —     —     2 
             

INCOME (LOSS) BEFORE INCOME TAXES

   (164)  637   66   (139)

INCOME TAX

   —     —     —     —   
             

INCOME (LOSS) FROM DISCONTINUED OPERATIONS

  $(164) $637  $66  $(139)
             

Assets associated with the Nucleic Acids segment consisted principally of the Company’s facility in Glasgow, Scotland. During the threesix months ended SeptemberJune 30, 2006, we2007, the Company completed an evaluation of the carrying value of net assets associated with former Nucleic Acids operating segment, including an assessment of tentative offers received for the sale of the only remaining Nucleic Acids’Glasgow facility and the associated equipment for $2.9 million, net of selling expenses, which resulted in Glasgow, Scotland (the “Facility”) and related equipment. In conjunction with this evaluation, we determined that it was appropriate to further reduce the carrying valuea gain of property, plant and equipment to $2.67 million resulting in an impairment charge of $0.44$0.1 million. The value assigned to property, plant and equipment consistsgain is reflected in the operating expenses of $2.62 million related to the Glasgow Facility and $0.05 million associated with related equipment. Furthermore, we also evaluated previously established liabilities related to the closure of the Facility. As a result of this review, we reversed liabilities of $0.39 milliondiscontinued operations during the three months ended September 30, 2006. At September 30, 2006 and December 31, 2005, we had accrued expenses of zero and $0.72 million, respectively, related to statutory payments to affected employees and other costs specifically attributable to closure of the Facility.period.

A restructuring plan was implemented during 2004 to better align the cost structure of the former Nucleic Acids operating segment with anticipated net sales. In conjunction with this plan, we had accrued expenses of $0.05 million and $0.22 million at September 30, 2006 and December 31, 2005, respectively, related to net rents on leased but unoccupied facilities. The future net lease payments required under these leases are approximately $0.03 million for the remainder of 2006 and $0.01 million in 2007.

Nine Months Ended September 30, 2006 and 2005

In the fourth quarter of 2005, we implemented a plan to exit our Nucleic Acids operating segment. Accordingly, we now reflect the related results as discontinued operations for all periods presented. Expenses that are not directly identified to

the Nucleic Acids operating segment or that are considered corporate overhead have not been allocated in arriving at the loss from discontinued operations. Summary results of operations of our former Nucleic Acids operating segment were as follows (in thousands):

   

Nine Months Ended

September 30,

 
   2006  2005 

NET SALES

  $1,142  $3,233 

COST OF GOODS SOLD

   843   3,132 
         

Gross profit

   299   101 

OPERATING EXPENSES:

   605   730 
         

LOSS FROM OPERATIONS

   (306)  (629)

OTHER INCOME

   2   11 
         

LOSS BEFORE INCOME TAXES

   (304)  (618)

INCOME TAX

   —     —   
         

LOSS FROM DISCONTINUED OPERATIONS

  $(304) $(618)
         

Liquidity and Capital Resources

Our working capital positions at SeptemberJune 30, 20062007 and December 31, 20052006 were as follows (in thousands):

 

  

September 30,

2006

  

December 31,

2005

  Change   

June 30,

2007

  

December 31,

2006

  Change 

Current assets (including cash and cash equivalents of $7,305 and $6,736, respectively)

  $15,722  $18,118  $(2,396)

Current assets (including cash and cash equivalents of $7,883 and $5,868, respectively)

  $18,175  $15,605  $2,570 

Current liabilities

   5,201   7,434   (2,233)   5,507   5,329   (178)
                    

Working capital

  $10,521  $10,684  $(163)  $12,668  $10,276  $2,392 
                    

The increase in working capital was largely driven by the proceeds from the sale of the Glasgow facility and related equipment for $2.9 million and the sale of an investment in equity securities of $0.9 million, offset by the net loss for the six months ended June 30, 2007.

Although we have experienced declining sales and recurring net losses (resulted(resulting in an accumulated deficit of $124.48$127 million at SeptemberJune 30, 2006)2007), management believes existing sources of liquidity, including cash and cash equivalents of $7.31$7.9 million, are sufficient to meet expected cash needs through 2007. We will need to increase our net sales and further reduce operating expenses in order to meet our liquidity needs for the foreseeable future.existing business on a long-term basis. We cannot assure you that we will be able to increase net sales or further reduce our expenses and, accordingly, we may not have sufficient sources of liquidity to continue operations of the Company indefinitely. If necessary, we believe that wemanagement believes they can further reduce costs and expenses to conserve working capital. However, such cost and expense reductions could have an adverse impact on ourthe Company’s new product pipeline and ultimately net sales. WeThe Company could also pursue additional financing, but ultimately, wethe Company must achieve sufficient net sales to consistently generate net income and cash flows from operations.flows.

Analysis of Cash Flows

NineSix Months Ended SeptemberJune 30, 20062007 and 20052006

Net Change in Cash and Cash Equivalents.Cash and cash equivalents increased $0.57$2.0 million during the ninesix months ended SeptemberJune 30, 20062007 compared to an increase of $0.36$0.6 million during the ninesix months ended SeptemberJune 30, 2005.2006. The 20062007 increase was the result of net cash provided by investing activities of $3.6 million, offset by net cash used by operating activities of $1.6 million. These were minimally offset from foreign currency exchange rates. The 2006 increase was similarly the result of net cash provided by operating activities of $0.7 million and the effect of foreign currency exchange rates of $0.1 million offset by net cash used in investing activities of $0.19$0.2 million.

Cash Flows used in Operating Activities. Cash flows used in operating activities totaled $1.6 million offset by netduring the six months ended June 30, 2007, compared to cash flows generated from operating activities of $0.48 million, net cash from financing activities of $0.01 and changes in foreign currency exchange rates of $0.27 million. The 2005 increase was the result of net cash used in operating activities of $1.98 million and changes in foreign currency exchange rates of $0.21 million, offset by net cash from investing and financing activities of $0.24 million and $2.31 million, respectively.

Cash Flows from Operating Activities. Cash flows provided from operating activities totaled $0.48 million during the nine months ended September 30, 2006 compared to cash flows used by operating activities of $1.98$0.7 million during the same period of 2005.2006. The increaseuse of cash flows in 2007 related primarily to the gain on sale of an investment in equity securities of $0.9 million, as well as higher inventory levels of $0.6 million related to the OEM instruments.

Cash flows generated from operating activities in 2006 related primarily to a net loss of $2.39$0.7 million offset by non-cash charges of $1.97.$1.0 million. Non-cash charges consisted of depreciation and amortization and non-cash stock-based compensation.amortization. Working capital and other adjustments increased cash flows from operating activities by $0.90 million.

The use of cash flows in 2005 related primarily to a net loss of $3.78 million offset by non-cash charges of $4.83 million. Non-cash charges consisted of depreciation and amortization and certain financing costs. Working capital and other adjustments decreased cash flows from operating activities by $3.03$0.4 million.

Cash Flows from Investing Activities. Cash flows provided by investing activities totaled $3.6 million during the six months ended June 30, 2007 compared to cash flows used in investing activities totaled $0.19 million during the nine months ended September 30, 2006 compared to cash flows provided by investing activities of $0.24$0.2 million during the same period of 2005. Cash flows used in investing activities in 2006 consisted principally of purchases of property and equipment

of $0.23 million and changes in other assets of $0.06 million offset by proceeds from asset sales of $0.10 million.2006. Cash flows provided by investing activities in 20052007 consisted primarily of sales proceeds from maturitiesour Glasgow facility and saleequipment of available for sale$2.9 million and sales proceeds of an investment in equity securities and asset sales offsetof $0.9 million. Cash flows used by investing activities in 2006 consisted of purchases of property and equipment.equipment and patent costs.

Cash Flows from Financing Activities. Cash flows from financing activities totaled $0.01 millionwere minimal during the ninesix months ended SeptemberJune 30, 2006 compared to $2.31 million during the same period of 2005. The principal source of cash flows from financing activities in 2005 was net changes in the Credit Line. Contemporaneously with the 2005 Private Placement, we repaid all outstanding principal2007 and accrued interest on the Laurus loans, which have been cancelled and are no longer available to us.June 30, 2006.

Obligations and Commitments

We lease certain equipment, vehiclesThe following identifies material obligations and operating facilities under non-cancellable operating leases that expire on various dates through 2014. The future minimum lease payments required under these leases are approximately $0.34 million for the remaindercommitments as of 2006, $0.73 million in 2007, $0.41 million in 2008, $0.38 million in 2009, $0.26 million in 2010 and $0.09 million through 2014.June 30, 2007:

During the three months ended September 30, 2006, we were notified by one of our OEM instrument suppliers (the “Supplier”) that its primary creditor filed a petition against the Supplier requesting the appointment of a receiver. The Supplier, its shareholders and creditors, and the court-appointed receiver are evaluating alternatives, including the sale or liquidation of the Supplier. We have sold 16 of the Supplier’s instruments over the past three years resulting in net sales of $2.99 million We continues to provide warranties and support for 11 of these instruments (six of which are in their initial 12-month warranty period), with such obligations expiring at various times through 2010. While agreements between us and the Supplier provide for the Supplier’s technologies (engineering designs, etc.) to be escrowed for our benefit, there are no assurances that we can continue to support these OEM customers without proprietary bioconsumables, component parts and technical assistance currently provided by the Supplier. We continue to coordinate with management of the Supplier, evaluate alternatives and evaluate the impact, if any, on our financial position, results of operations or cash flows.

   Payments Due by Period
Contractual Obligations                    After

Millions of dollars

  Total  2007  2008  2009  2010  2011  2011

Operating leases(a)

  $3.75  $0.54  $0.86  $0.77  $0.66  $0.50  $0.42

Purchase obligations(b)

   1.25   1.25   —     —     —     —     —  
                            

Total contractual obligations

  $5.00  $1.79  $0.86  $0.77  $0.66  $0.50  $0.42
                            

(a)Operating leases include facility, automobile and other equipment leases.
(b)Purchase obligations include purchase commitments for components used in WAVE Systems and OEM instruments.

At September 30, 2006 and December 31, 2005, firm commitments to vendors to purchase components used in WAVE® systems and instruments manufactured by others totaled $1.16 million and $0.88 million, respectively. We expect to pay the majority of these purchase commitments during 2006 and 2007.

Off BalanceOff-Balance Sheet Arrangements

At SeptemberJune 30, 20062007 and December 31, 2005,2006, we did not have any relationships with unconsolidated entities or financial partnerships, such as entities often referred to as structured finance or special purpose entities, which would have been established for the purpose of facilitating off-balance sheet arrangements or other contractually narrow or limited purposes.

Critical Accounting Policies and Estimates

Accounting policies used in the preparation of the consolidated financial statements may involve the use of management judgments and estimates. Certain of our accounting policies are considered critical as they are both important to the portrayal of our financial statements and they require significant or complex judgments on the part of management. Our judgments and estimates are based on experience and assumptions that we believe are reasonable under the circumstances. Further, we evaluate our judgments and estimates from time to time as circumstances change. Actual financial results based on judgments or estimates may vary under different assumptions or circumstances. Our critical accounting policies are discussed in our annual report on Form 10-K for the fiscal year ended December 31, 2005.2006. There have been no significant changes with respect to these estimates during the ninesix months ended SeptemberJune 30, 2006.2007, except for the treatment of the contingency accruals.

Effective January 1, 2007, we began to measure and record tax contingency accruals in accordance with Financial Accounting Standards Board (“FASB”) Interpretation No. 48,Accounting for Uncertainty in Income Taxes,an Interpretation of FASB Statement No. 109 (“FIN 48”). Under FIN 48, tax benefits are recognized only for tax positions that are more likely than not to be sustained upon examination by tax authorities. The amount recognized is measured as the largest amount of benefit that is more than likely not to be realized upon ultimate settlement. Unrecognized tax benefits are tax benefits claimed in our tax returns that do not meet these recognition and measurement standards. For additional information on the adoption of FIN 48, see Note H in Part I, Item 1 of this report.

Recently Issued Accounting Pronouncements

In December 2004, the FASB issued SFAS No. 153, “Exchanges of Nonmonetary Assets.” This statement addresses the prospective measurementPlease refer to our annual report on Form 10-K for nonmonetary exchanges of nonmonetary assets. It specifies that a nonmonetary exchange has commercial substance if the future cash flows of the entity are expected to change significantly as a result of the exchange. SFAS No. 153 was effective for us beginning July 1, 2006. We are assessing the final impact of this standard on our financial position, results of operations or cash flows.

In July 2006, the FASB issued Interpretation (“FIN”) No. 48, “Uncertainty in Income Taxes.” FIN 48 applies to all tax positions within the scope of Statement 109 and clarifies when and how to recognize tax benefits in the financial statements with a two-step approach of recognition and measurement. FIN 48 will become effective in the first quarter of 2007.

Management continues to evaluate the effect that adoption of FIN 48 will have on our consolidated results of operations and financial position.

In September 2006, the SEC issued Staff Accounting Bulletin. 108,Considering the Effects of Prior Year Misstatements when Quantifying Misstatements in Current Year Financial Statements (SAB 108). SAB 108 provides interpretive guidance on how the effects of prior-year uncorrected misstatements should be considered when quantifying misstatements in current year financial statements. SAB 108 requires registrants to quantify misstatements using both an income statement and balance sheet approach and then evaluate whether either approach results in a misstatement that, when all relevant quantitative and qualitative factors are considered, is material. If prior year errors that had been previously considered immaterial are now considered material based on either approach, no restatement is required so long as management properly applied its previous approach and all relevant facts and circumstances were considered. If prior year’s financial statements are not restated, the cumulative effect adjustment is recorded in opening accumulated earnings (deficit) as of the beginning of the fiscal year of adoption. SAB 108 is effective for us at the end ofended December 31, 2006. We do not expect the adoption of SAB 108 willThere have a material impact on our Consolidated Financial Statementsbeen no changes to those listed except as noted in Note B.

Impact of Inflation

We do not believe that price inflation had a material adverse effect on our financial condition or results of operations during the periods presented.

Item 3.Quantitative and Qualitative Disclosures about Market Risk

Item 3. Quantitative and Qualitative Disclosure about Market RiskForeign Currency Translation Risk.

Previously, our principal market risk was interest rate risk on our variable-rate borrowings under the Laurus Loans. During the fourth quarter of 2005, we repaid the entire principal balance of the Laurus Loans with the proceeds from the 2005 Private Placement and terminated these loans. Accordingly, we no longer have any borrowings which subject us to material interest rate risk.

During the ninesix months ended SeptemberJune 30, 20062007 and 2005,2006, our international sales have represented approximately 70%more than 68% of our net sales. These sales of products in foreign countries are mainly completed in either British Pounds Sterling or the Euro. Additionally, we have two wholly ownedwholly-owned subsidiaries, Transgenomic LTD.,Limited, and Cruachem LTD.,Limited, whose operating currencies are British Pounds Sterling and the Euro. Results of operations for our foreign subsidiaries are translated using the average exchange rate during the period. Assets and liabilities are translated at the exchange rate in effect on the balance sheet dates. As a result we are subject to exchange rate risk. The operational expenses of our foreign subsidiaries help to reduce the currency exposure we have based on our sales denominated in foreign currencies by converting foreign currencies directly into goods and services. As such, we feel we do not have a material exposure to foreign currency rate fluctuations at this time.

Item 4. Controls and Procedures

Item 4.Controls and Procedures

 

 (a)Evaluation of Disclosure Controls and Procedures. A review and evaluation was performed by the our President, Chief Executive Officer (“CEO”) and PrincipalChief Financial Officer (who was the same person at September 30, 2006),(“CFO”) of the effectiveness of the design and operation of our disclosure controls and procedures as of the end of the period covered by this quarterly report. Based on that review and evaluation, the President, Chief Executive OfficerCEO and Principal Financial OfficerCFO concluded that the our currentCorporation’s disclosure controls and procedures, as designed and implemented, were effective in assuring that information required to be disclosed is recorded, processed, summarized and reported in the reports we submit under the Securities Exchange Act of 1934.

 

 (b)Change in Internal Control Over Financial Reporting. There have been no changes in the our internal control over financial reporting during the quarter that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

PART II. OTHER INFORMATION

Item 1. Legal Proceedings

Item 1.Legal Proceedings

We are subject to a number of claims of various amounts which arise out of the normal course of business. In our opinion, the disposition of pending claims will not have a material adverse effect on our financial position, results of operations or cash flows.

Item 1A. Risk Factors

Item 1A.Risk Factors

There have been no material changes in our risk factors from those described in Item 1A of our annual report on Form 10-K for the fiscal year ended December 31, 2005.2006.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds

We made no repurchases of our common stock during the nine months ended September 30, 2006; therefore, tabular disclosure is not presented.

Item 4.Submission of Matters to a Vote of Security Holders

Item 4. Submission of Matters to a Vote of Security Holders

(a) We held our Annual Meeting of Stockholders on July 12, 2006May 23, 2007 in Omaha, Nebraska. The inspector of the election issued its certified final report on July 12, 2006,Nebraska for the matters voted upon at such Annual Meeting.

(b) Not applicable.

(c) The proposals voted upon at the Annual Meeting were for electionpurpose of the two individuals as directors, the ratification of independent auditors for the year ending December 31, 2006 and approval of the 2006 Equity Incentive Plan.

Proposal 1 – To electelecting two Class IIII directors (for terms to expire in 2010) and one Class III director (for a term to expire in 2009). The following sets forth the results of the voting at the Annual Meeting:

 

   Votes For  Votes Withheld

Greg J. Duman

  31,474,617  3,929,473

Roland J. Santoni

  34,852,140  551,950

Director Nominee

  Class/Term Ending  Votes For  Votes Withheld

Craig J. Tuttle

  Class I /2010  30,063,591  816,802

Frank R. Witney, Ph.D.

  Class I /2010  30,809,567  70,826

Rodney S. Markin, M.D., Ph.D.

  Class III /2009  30,809,567  70,826

Proposal 2 – To ratifyAccordingly, Messrs. Tuttle, Witney and Markin were re-elected to the appointmentBoard of Deloitte & Touche LLPDirectors at the Annual Meeting. Each of our other directors, Gregory T. Sloma, Jeffrey L. Sklar, M.D., Ph.D., and Gregory J. Duman, continued in office as independent auditor fora director after the year ending December 31, 2006.Annual Meeting.

 

Votes For Votes Against Votes Abstained
35,280,619 109,459 14,012

Proposal 3 – To approve amendments to the Fourth Amended and Restate 1997 Stock Option Plan in the form of the 2006 Equity Incentive Plan.

Votes For Votes Against Votes Abstained Broker Non-Votes
24,874,465 933,876 109,121 9,486,286

(d) Not applicable.

Item 6. Exhibits

Item 6.Exhibits

 

(a)Exhibits

3.1 Third Amended and Restated Certificate of Incorporation of the Registrant (incorporated by reference to Exhibit 3.1 to Registrant’s Report on Form 10-Q (Registration No. 000-30975) filed on November 14, 2005.

3.2 Bylaws of the Registrant (incorporated by reference to Exhibit 3.2 to Registration Statement on Form S-1 (Registration No. 333-32174) filed on March 10, 2000)

4 Form of Certificate of the Registrant’s Common Stock (incorporated by reference to Exhibit 4 to Registration Statement on Form S-1 (Registration No. 333-32174) filed on March 10, 2000)

10.1 Amendment No. 1 to the Employment Agreement, effective July 12, 20006, by and between Transgenomic, Inc. and Craig J. Tuttle.

31 Certifications pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

32 Certifications pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

  3.1Third Amended and Restated Certificate of Incorporation of the Registrant (incorporated by reference to Exhibit 3.1 to Registrant’s Report on Form 10-Q (Registration No. 000-30975) filed on November 14, 2005
  3.2Amended and Restated Bylaws of the Registrant filed on May 25, 2007
  4Form of Certificate of the Registrant’s Common Stock (incorporated by reference to Exhibit 4 to Registration Statement on Form S-1 (Registration No. 333-32174) filed on March 10, 2000
10.1Stock Purchase Agreement, dated May 10, 2007, between the Registrant and New River Management IV, LP
31Certifications pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
32Certifications pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

 

 TRANSGENOMIC, INC.
Date: NovemberAugust 14, 20062007 By: 

/s/ CRAIG J. TUTTLE

  

Craig J. Tuttle

President and Chief Executive Officer

(authorized officer and principal financial officer)

 

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