The accompanying notes are an integral part of these condensed consolidated financial statements.


		2021			2020			2021			2020		For the Three Months Ended March 31,
	For the Three Months Ended June 30,						For the Six Months Ended June 30,						2022			2021
		2021			2020			2021			2020
Operating Expenses:
Research and development	$	355,051		$	159,926		$	590,815		$	417,471		$	464,505		$	235,764
Research and development - related party		12,500			50,000			47,975			111,667			14,500			35,475
General and administrative		627,548			693,405			1,477,665			1,107,525			573,667			850,117
Total Operating Expenses		995,099			903,331			2,116,455			1,636,663			1,052,672			1,121,356
Loss From Operations		(995,099	)		(903,331	)		(2,116,455	)		(1,636,663	)		(1,052,672	)		(1,121,356	)

Other (Expense) Income:
Interest expense		(140,305	)		(81,164	)		(396,688	)		(157,647	)		(48,412	)		(256,383	)
Interest expense - related parties		(22,540	)		(12,715	)		(47,044	)		(23,881	)		(118,353	)		(24,504	)
Amortization of debt discount		(155,169	)		(36,228	)		(277,932	)		(44,530	)		(66,537	)		(122,763	)
Change in fair value of derivative liabilities		-			-			-			16,977
Amortization of debt discount - related party														(6,601	)		-
Gain on forgiveness of accrued interest		-			-			49,983			-			-			49,983
Loss on extinguishment of notes payable		-			(131,250	)		(49,718	)		(132,691	)		-			(49,718	)
Total Other Expense		(318,014	)		(261,357	)		(721,399	)		(341,772	)		(239,903	)		(403,385	)
Net Loss		(1,313,113	)		(1,164,688	)		(2,837,854	)		(1,978,435	)		(1,292,575	)		(1,524,741	)
Dividend attributable to Series A preferred stockholders		(225,873	)		(211,885	)		(449,264	)		(423,190	)
Dividend attributable to Series A and Series C preferred stockholders														(324,917	)		(223,391	)
Net Loss Applicable to Common Stockholders	$	(1,538,986	)	$	(1,376,573	)	$	(3,287,118	)	$	(2,401,625	)	$	(1,617,492	)	$	(1,748,132	)

Net Loss Per Common Share - Basic and Diluted	$	(0.05	)	$	(0.05	)	$	(0.10	)	$	(0.08	)	$	(0.05	)	$	(0.05	)

Weighted Average Common Shares Outstanding -
Basic and Diluted		32,663,482			30,020,692			32,610,275			29,570,645
Weighted Average Common Shares Outstanding - Basic and Diluted														34,400,181			32,556,476

The accompanying notes are an integral part of these condensed consolidated financial statements.

	2021			2020
	For The Six Months Ended						For Three Months Ended
	June 30,						March 31,
	2021			2020			2022			2021

Cash Flows From Operating Activities:
Net loss	$	(2,837,854	)	$	(1,978,435	)	$	(1,292,575	)	$	(1,524,741	)
Adjustments to reconcile net loss to net cash used in operating activities:
Change in fair value of derivative liabilities		-			(16,977	)
Amortization of debt discount		277,932			44,530			73,138			122,763
Gain on forgiveness of accrued interest		(49,983	)		-			-			(49,983	)
Loss on extinguishment of notes payable		49,718			132,691			-			49,718
Non-cash interest expense - warrants		218,985			18,668			33,609			180,991
Stock-based compensation:
Options		206,400			-			-			206,400
Warrants		67,707			16,025			4,960			31,372
Common Stock		9,637			321,397
Changes in operating assets and liabilities:
Prepaid expenses		(37,695	)		10,639			82,514			3,907
Other current assets		21,584			(4,944	)		(6,652	)		(12,399	)
Accounts payable		146,895			310,391			109,818			(40,670	)
Accrued expenses		(463,996	)		(142,426	)		(178,453	)		(53,903	)
Accrued expenses - related parties		(110,000	)		(63,833	)		-			(122,500	)
Accrued interest		223,638			149,397			(80,157	)		99,174
Accrued interest - related parties		1,488			13,463			213,275			740
Accrued compensation		17,968			35,619			12,353			(5,150	)
Net Cash Used In Operating Activities		(2,257,576	)		(1,153,795	)		(1,028,170	)		(1,114,281	)

Cash Flows From Financing Activities:
Proceeds from advances payable		-			100,000
Proceeds from issuance of notes payable		-			100,000
Proceeds from issuance of convertible notes payable		2,422,250			1,075,000			95,000			1,197,250
Proceeds from issuance of Series A Preferred Stock		-			125,000
Proceeds from issuance of convertible notes payable - related party								1,000,000			-
Repayment of notes payable		(199,588	)		(100,000	)		-			(100,000	)
Repayment of convertible notes payable		(125,000	)		(68,000	)		-			(125,000	)
Repayment of advances payable		-			(105,000	)
Repayment of financing liability								(27,926	)		-
Net Cash Provided By Financing Activities		2,097,662			1,127,000			1,067,074			972,250
Net Decrease In Cash and Restricted Cash		(159,914	)		(26,795	)

Cash and Restricted Cash - Beginning of Period		245,119			27,908
Cash and Restricted Cash - End of Period	$	85,205		$	1,113

Cash and restricted cash consisted of the following:
Cash	$	81,705		$	-
Restricted cash		3,500			-
Cash and Restricted cash	$	85,205		$	-
Net Increase (Decrease) In Cash								38,904			(142,031	)
Cash - Beginning of Period								93,095			245,119
Cash - End of Period							$	131,999		$	103,088

Supplemental Disclosures of Cash Flow Information:
Cash paid for:
Interest	$	-		$	-		$	-		$	-
Income taxes	$	-		$	-		$	30,515		$	-

Non-cash investing and financing activities:
Original issue discount in connection with convertible note payable	$	-		$	3,000
Common stock issued in connection with payment of Series A Convertible Preferred Stock dividends in-kind	$	474,475		$	430,905
Reclassification of derivative liabilities to equity	$	-		$	345,830
Issuance of common stock pursuant to cashless warrant exercise	$	125		$	-		$	-		$	125
Accrued interest converted into notes payable	$	41,950		$	-		$	-		$	41,950
Issuance of warrants in connection with the issuance of notes payable	$	234,478		$	-		$	8,043		$	196,966
Accrual of warrant obligations in connection with issuance of notes payable							$	114,727		$	-
Issuance of warrants in satisfaction of accrued interest	$	82,350		$	-		$	-		$	82,350
Accrual of earned preferred stock dividends	$	(449,264	)	$	(423,190	)	$	(324,917	)	$	(223,391	)
Issuance of placement agent warrants	$	-		$	10,907
Issuance of common stock as debt discount in in connection with extension of notes payable	$	-		$	188,125
Repayment of convertible note payable and accrued interest by third party	$	-		$	100,896
Warrants and conversion options issued in connection with issuance and extension of notes payable	$	-		$	161,256
Warrants issued in connection with issuance of advance payable	$	-		$	24,386
Conversion of convertible notes payable and accrued interest into Series C Preferred Stock and common stock							$	1,433,095		$	-

The accompanying notes are an integral part of these condensed consolidated financial statements.

Note 1 - Business Organization, Nature of Operations, Risks and Uncertainties and Basis of Presentation

Cell Source, Inc. (“Cell Source”, “CSI” or the “Company”) is a Nevada corporation formed on June 6, 2012 that is the parent company of Cell Source Limited (“CSL”), a wholly owned subsidiary which was founded in Israel in 2011 in order to commercialize a suite of inventions relating to certain cancer treatments. The Company is a biotechnology company focused on developing cell therapy treatments based on the management of immune tolerance. The Company’s lead prospective product is its patented Veto Cell immune system management technology, which is an immune tolerance biotechnology that enables the selective blocking of immune responses. CSL’s Veto Cell immune system management technology is based on technologies patented, owned, and licensed to CSL by Yeda Research and Development Company Limited, an Israeli corporation (“Yeda”) (see Note 8, Commitments and Contingencies). The Company’s target indications include: lymphoma, leukemia and multiple myeloma through the facilitation of safer and more accessible stem cell (e.g. bone marrow) transplantation acceptance, treatment of end stage kidney disease and other non-malignant organ diseases through improved organ transplantation (broadened donor pool, reduced dependence on post-transplant anti-rejection therapy), and ultimately treating a variety of cancers and non-malignant diseases.

~~In March 2020, the World Health Organization declared COVID-19, a~~The novel ~~strain of~~ coronavirus ~~a pandemic. During 2020 and continuing into 2021, the global economy has been, and~~(“COVID-19”) pandemic continues to ~~be, affected by COVID-19. While the Company continues to see signs of~~impact global economic recovery as certain governments began to gradually ease restrictions, provide economic stimulus and vaccine distribution accelerated, the rate of recovery on a global basis has been affected by resurgence of the virus or its variants in certain jurisdictions causing reinstatement of restrictions in certain jurisdictions.conditions. The Company ~~continues to monitor~~is closely monitoring the ~~effects~~outbreak of COVID-19 and its impact on the Company’s operations, financial position, cash flows and its industry in general. The Company considered the impact of COVID-19 on its business and operational assumptions and estimates, and determined there were no material adverse impacts on the Company’s condensed consolidated results of operations and financial position ~~at June 30, 2021.~~as of March 31, 2022.

~~The full extent of~~Similarly, the ~~future impact of~~economic uncertainty caused by the COVID-19 onpandemic has made and may continue to make it difficult for the ~~Company’s operations and financial condition is uncertain. Accordingly, COVID-19 could have a material adverse effect on the Company’s business,~~Company to forecast operating results, ~~of operations, financial condition and prospects during 2021 and beyond,~~ including the timing and ability of the Company to initiate and/or complete current and/or future preclinical studies and/or clinical trials, disrupt the Company’s regulatory activities, and/or have other adverse effects on the Company’s clinical development. The duration and extent of the impact from the COVID-19 pandemic depend on future developments that cannot be accurately predicted at this time, and if the Company is not able to respond to and manage the impact of such events effectively, the Company’s business may be harmed.

There can be no assurance that precautionary measures, whether adopted by the Company or imposed by others, will be effective, and such measures could negatively affect the Company’s condensed consolidated financial condition, cash flows, and results of operations. The financial statements do not include any adjustments that might result from the outcome of this uncertainty.

The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with accounting principles generally accepted in the United States of America (“U.S. GAAP”) for interim financial information and with the instructions to Form 10-Q and Article 8 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by U.S. GAAP for complete financial statements. In the opinion of management, such statements include all adjustments (consisting only of normal recurring items) which are considered necessary for a fair presentation of the condensed consolidated financial position of the Company as of ~~June 30, 2021~~March 31, 2022 and the condensed consolidated results of its operations and cash flows for the three ~~and six~~ months ended ~~June 30, 2021~~March 31, 2022 and ~~2020.~~2021. The results of operations for the three ~~and six~~ months ended ~~June 30, 2021~~March 31, 2022 are not necessarily indicative of the operating results for the full year ending December 31, ~~2021~~2022 or any other period. These condensed consolidated financial statements should be read in conjunction with the audited consolidated financial statements and related disclosures of the Company as of December 31, ~~2020~~2021 and for the year then ended which were included in the Company’s Annual Report on Form 10-K that was filed with the Securities and Exchange Commission (“SEC”) on April 15, ~~2021.~~2022.

During the ~~six~~three months ended ~~June 30, 2021,~~March 31, 2022, the Company had not generated any revenues, had a net loss of approximately $~~2,838,000~~ 1,293,000 and had used cash in operations of approximately $~~2,258,000~~1,028,000. As of ~~June 30, 2021,~~March 31, 2022, the Company had a working capital deficiency of approximately $~~10,030,000~~9,997,000 and an accumulated deficit of approximately $~~28,544,000~~32,471,000. ~~Subsequent to June 30, 2021~~As of March 31, 2022 and ~~as more fully described in Note 9,~~ ~~Subsequent Events~~~~, the Company received proceeds of $575,000~~ through the ~~issuance~~date of ~~convertible notes.~~this filing, notes payable with principal amounts totaling $1,554,912 and $1,408,000, respectivelywere past due and are classified as current liabilities on the condensed consolidated balance sheet as of March 31, 2022. The Company will continue to incur net operating losses to fund operations. These conditions raise substantial doubt about the Company’s ability to continue as a going concern for at least one year from the date these financial statements are issued. Subsequent to March 31, 2022 and as more fully described in Note 9, Subsequent Events, the Company received aggregate proceeds of $150,000 from the issuance of convertible notes payable.

The Company is currently funding its operations on a month-to-month basis. While there can be no assurance that it will be successful, the Company is in active negotiations to raise additional capital. The Company’s primary sources of operating funds since inception have been equity and debt financings. Management’s plans include continued efforts to raise additional capital through debt and equity financings. There is no assurance that these funds will be sufficient to enable the Company to fully complete its development activities or attain profitable operations. If the Company is unable to obtain such additional financing on a timely basis or, notwithstanding any request the Company may make, if the Company’s debt holders do not agree to convert their notes into equity or extend the maturity dates of their notes, the Company may have to curtail its development, marketing and promotional activities, which would have a material adverse effect on the Company’s business, financial condition and results of operations, and ultimately the Company could be forced to discontinue its operations and liquidate.

The accompanying condensed consolidated financial statements have been prepared in conformity with U.S. GAAP, which contemplate continuation of the Company as a going concern and the realization of assets and satisfaction of liabilities in the normal course of business. The carrying amounts of assets and liabilities presented in the financial statements do not necessarily purport to represent realizable or settlement values. The condensed consolidated financial statements do not include any adjustment that might result from the outcome of this uncertainty.

Since the date of the Annual Report on Form 10-K for the year ended December 31, ~~2020,~~2021, there have been no material changes to the Company’s significant accounting policies.

The Company computes basic net loss per share by dividing net loss applicable to common stockholders by the weighted average number of common shares outstanding for the period and excludes the effects of any potentially dilutive securities. Diluted earnings per share includes the dilution that would occur upon the exercise or conversion of all dilutive securities into common stock using the “treasury stock” and/or “if converted” methods, as applicable. ~~Weighted average shares outstanding for the three and six months ended June 30, 2021 and 2020 includes the weighted average impact of warrants to purchase an aggregate of~~

0 ~~and~~ ~~2,043,835~~ ~~shares of common stock because their exercise price was determined to be nominal.~~

The common stock equivalents associated with the following securities are excluded from the calculation of weighted average dilutive common shares because their inclusion would have been anti-dilutive:

Schedule of Weighted Average Dilutive Common Shares ~~Anti-dilutive~~Anti-Dilutive

	June 30,				March 31,
	2021		2020		2022		2021

Options		6,182,004		3,782,004		6,182,004		6,182,004
Warrants		9,946,388		5,744,477		11,964,079		8,966,388
Convertible notes [1] [2]		1,760,041		3,258,424		3,074,310		1,708,020
Convertible preferred stock		13,421,950		12,617,490		17,976,380		13,421,950
Total		31,310,383		25,402,395		39,196,773		30,278,362

~~Certain prior period balance sheet amounts have been reclassified to conform to the fiscal 2021 presentation. These reclassifications have no impact on the previously reported net loss.~~

On May 3, 2021, the Financial Accounting Standards Board (the “FASB”) issued ASU 2021-04, Earnings Per Share (Topic 260), Debt—Modifications and Extinguishments (Subtopic 470-50), Compensation—Stock Compensation (Topic 718), and Derivatives and Hedging—Contracts in Entity’s Own Equity (Subtopic 815-40): Issuer’s Accounting for Certain Modifications or Exchanges of Freestanding Equity-Classified Written Call Options. This new standard provides clarification and reduces diversity in an issuer’s accounting for modifications or exchanges of freestanding equity-classified written call options (such as warrants) that remain equity classified after modification or exchange. This standard is effective for fiscal years beginning after December 15, 2021, including interim periods within those fiscal years. Issuers should apply the new standard prospectively to modifications or exchanges occurring after the effective date of the new standard. Early adoption is permitted, including adoption in an interim period. If an issuer elects to early adopt the new standard in an interim period, the guidance should be applied as of the beginning of the fiscal year that includes that interim period. The Company is currently evaluating this new standard and its impact on the Company’s condensed consolidated financial statements and related disclosures.

The following table provides a summary of the changes in fair value, including net transfers in and/or out, of all Level 3 liabilities measured at fair value on a recurring basis using unobservable inputs during the ~~six~~three months ended ~~June 30,~~March 31, 2022 and 2021:

Schedule of Changes in Fair Value of Liabilities Measured at Fair Value on a Recurring Basis

Financial assets are considered Level 3 when their fair values are determined using pricing models, discounted cash flow methodologies or similar techniques and at least one significant model assumption or input is unobservable. The Company’s Level 3 liabilities shown in the above table consist of accrued obligations to issue warrants and common stock.

In applying the Black-Scholes option pricing model utilized in the valuation of Level 3 liabilities, the Company used the following approximate assumptions:

	For the Three Months Ended						For the Six Months Ended						For the Three Months Ended
	June 30,						June 30,						March 31,
	2021			2020			2021			2020			2022			2021

Risk-free interest rate		0.67%-0.87%			0.24%-0.29%			0.64%-0.92%			0.33%-1.55%			2.42%-2.44	%		0.64%-0.92	%
Expected term (years)		4.00-5.00			4.00-5.00			4.00-5.00			0.52 - 5.00			4.00-5.00			4.00-5.00
Expected volatility		90	%		110	%		90	%		110	%		90	%		90	%
Expected dividends		0.00	%		0.00	%		0.00	%		0.00	%		0.00	%		0.00	%

The expected term used is the contractual life of the instrument being valued. Since the Company’s stock does not have significant trading volume, the Company is utilizing an expected volatility based on a review of the historical volatilities, over a period of time, equivalent to the expected life of the instrument being valued, of similarly positioned public companies within its industry. The risk-free interest rate was determined from the implied yields from U.S. Treasury zero-coupon bonds with a remaining term consistent with the expected term of the instrument being valued.

As of ~~June 30, 2021~~March 31, 2022 and December 31, ~~2020,~~2021, the Company had an obligation to issue ~~169,594~~ 154,495~~and~~ ~~154,495~~ shares of common stock to service providers that had a fair value of $~~79,709~~ 52,528~~and $72,613~~, ~~respectively,~~ which was a component of accrued compensation on the condensed consolidated balance ~~sheet.~~sheets.

See Note 6, Stockholders’ Deficiency – Common Stock and Stock Warrants for additional details associated with the issuance of common stock and warrants.

As of ~~June 30, 2021~~March 31, 2022 and through the date of this filing, notes and convertible notes payable with principal amounts totaling $~~1,933,412~~1,554,912 and $~~2,870,634~~1,408,000, respectively were past due and are classified as current liabilities on the condensed consolidated balance sheet as of ~~June 30, 2021.~~March 31, 2022. Such notes continue to accrue interest and all relevant penalties have been accrued as of ~~June 30, 2021.~~March 31, 2022. Of such past due notes payable, a holder of a note with principal amount of $250,000 issued a notice of default. See Note 8, Commitments and Contingencies – Litigationfor additional details. The Company is in negotiations with ~~all~~certain holders of notes payable to extend the maturity dates of such notes or to convert the principal and accrued interest into equity.

During the three months ended ~~June 30,~~March 31, 2022 and 2021, ~~and 2020,~~ the Company recorded interest expense of $~~162,845~~ 166,765and $~~93,879~~280,887, respectively, and amortization of debt discount of $~~155,169~~ 73,138and $~~36,228~~122,763~~, respectively. During the six months ended June 30, 2021 and 2020, the Company recorded interest expense of $443,732~~ ~~and $181,528, respectively, and amortization of debt discount of $277,932~~ ~~and $44,530~~, respectively. As of ~~June 30, 2021~~March 31, 2022 and December 31, ~~2020,~~2021, the Company had $~~1,292,183~~ 1,406,317and $~~997,244~~1,182,225, respectively, of accrued interest (including interest in the form of warrants (see Note 4)) and penalties related to notes payable, which is included with accrued interest and accrued interest – related parties on the condensed consolidated balance sheets.

During the ~~six~~three months ended ~~June 30, 2021,~~March 31, 2022, the Company issued convertible notes payable in the aggregate principal amount of $~~922,250~~ 95,000which have maturity dates ranging from ~~July 7, 2021~~August 2, 2022 through ~~December 23, 2021~~September 22, 2022. The notes accrue interest at 8% per annum and are convertible at any time at the option of the holder into the Company’s Series C Convertible Preferred Stock ~~(the “Series C Preferred Stock”)~~ at a conversion price of $7.50. per share. The notes ~~shall become convertible (i) at the holder’s option beginning on the date that the Company first issues any shares of its~~automatically convert into Series C Convertible Preferred Stock ~~or (ii) automatically~~ on the maturity date. In connection with the issuances, the Company issued ~~five~~five-year~~-year~~ immediately vested warrants to purchase an aggregate of ~~737,800~~56,000 shares of common stock at an exercise price $1.25 per share. The warrants had an issuance date relative fair value of $8,043 which will be amortized over the term of the notes.

In March 2022, an aggregate of $1,375,698 of principal outstanding under convertible notes automatically converted into an aggregate of 183,422 shares of Series C Convertible Preferred Stock and the Company elected to convert an aggregate of $57,399 of interest accrued under such notes into an aggregate of 76,530 shares of common stock. The aggregate note principal had a conversion price of $7.50 per share and the common stock was valued at $0.75 per share for purposes of the interest payment. The Company analyzed the notes for a beneficial conversion feature and determined that there was none because the notes have an effective conversion price of $0.75per share of underlying common stock, which exceeds the $0.34per share commitment date closing market price of the common stock.

On March 10, 2022, the Board of Directors of the Company appointed George Verstraete as a member of the Board.

The Company and Mr. Verstraete entered into a promissory note agreement dated March 10, 2022, whereby Mr. Verstraete, at his discretion, can loan up to $6,000,000 to the Company. The holder has agreed to loan an aggregate of $2,500,000 to the Company under the note. The note bears interest at a rate of 10% per annum and will mature twelve months from the date of issuance. Mr. Verstraete has the right, at his option, to convert the note into shares of the Company’s Series B Convertible Preferred Stock at a conversion price of $7.50 per share at any time after the creation and sale of the Series B Convertible Preferred Stock. Interest accruing under the note will be payable upon the maturity of the note and may be paid at the Company’s option in either cash or shares of the Company’s common stock (calculated based upon $0.75 per share for purposes of calculating the number of shares of common stock to be issued). For each $500,000 advanced under the note, Mr. Verstraete will be issued a warrant to purchase 400,000 shares of the Company’s Common Stock at an exercise price of $1.25 per share. Each warrant will have a five year term. As of March 31, 2022, the Company had received $1,000,000 under the note. In connection with the issuance, the Company accrued an obligation to issue five-year immediately vested warrants to purchase an aggregate of 800,000 shares of common stock at an exercise price $1.25 per share. The warrants had an issuance date relative fair value of $~~151,769~~114,727 which will be amortized over the term of the notes. See Note 9, Subsequent Events - Convertible Notes Payable - Related Parties for additional details of an additional $1,000,000 advanced under the note subsequent to March 31, 2022.

~~On January 28, 2021, the Company issued a convertible note payable in the amount of $647,222~~ ~~which matures on~~ ~~July 28, 2021in exchange for another note in the principal amount of $555,556~~ ~~that accrued interest at~~ 13~~% per annum and had accrued interest of $41,948. The new note accrues interest at~~ 8~~% per annum and such interest is payable at maturity, at the Company’s option, in cash or as payment-in-kind in common stock at a rate of $0.75~~ ~~per share.~~ The note shall become convertible, (i) beginning on the date that the Company first issues any shares of its Series C Preferred Stock, at the holder’s option into Series C Preferred Stock at a price of $~~7.50~~ ~~per share or (ii) automatically on the maturity date into either Series C Preferred Stock at a price of $7.50~~ ~~per share or common stock at price of $0.75~~ ~~per share. If the Company fails to designate the Series C Preferred Stock by July 28, 2021, the note will be automatically converted into common stock at a price of $0.75~~ ~~per share. In connection with the issuance of the convertible note, the Company issued a~~ ~~five-year immediately vested warrant to purchase~~ ~~517,778~~ ~~shares of common stock at an exercise price $1.25~~ ~~per share. The warrants had an issuance date fair value of $106,183~~ ~~that was recognized immediately. The Company determined the transaction was an extinguishment and, as a result, recognized a loss on extinguishment of notes payable of $49,718~~ ~~on the condensed consolidated statement of operations during the six months ended June 30, 2021.~~

~~On March 2, 2021, the Company amended a previously issued convertible note in the principal amount of $2,000,000. In connection with this amendment, during the three months ended March 31, 2021, the Company (i) received further proceeds of $500,000, (ii) increased the principal amount from $2,000,000~~ ~~to $4,000,000~~ ~~and (iii) issued~~ ~~five-year immediately vested warrants for the purchase of~~ ~~800,000~~ ~~shares of common stock at an exercise price of $1.25per share, of which, warrants to purchase~~ ~~400,000~~ ~~shares of common stock were accrued for as December 31, 2020, and had an issuance date fair value of $164,700~~ ~~which will be amortized over the term of the note.~~ ~~On June 18, 2021, the Company amended and restated the note in the principal amount of $4,000,000~~. ~~In connection with this amendment, during the three months ended June 30, 2021, the Company (i) received further proceeds of $1,000,000~~ ~~in connection with the note by means of the payment by the lender of outstanding obligations to third parties, (ii)~~ ~~increased the principal amount from $4,000,000~~ ~~to $6,000,000~~ ~~and (iii)~~ ~~agreed to issue a~~ ~~five-year~~ ~~immediately vested warrant to purchase~~ ~~800,000~~ ~~shares of common stock with an issuance date fair value of $164,857~~ ~~which will be amortized over the term of the note.~~ ~~The Company may elect to convert the amended and restated note into shares of Series B Convertible Preferred Stock at a conversion price of $7.50~~ ~~per share at any time after the creation of the Series B Convertible Preferred Stock and before the maturity date.~~ ~~As of June 30, 2021, an aggregate of $3,500,000~~ ~~of proceeds were outstanding under the note. The warrant to purchase~~ ~~800,000~~ ~~shares of common stock had not been issued as of June 30, 2021 and, accordingly, the obligation was accrued for as of June 30, 2021.~~

~~On March 11, 2021, the Company entered into convertible note purchase agreements with two noteholders whereby the Company agreed to repurchase an aggregate of $125,000~~ of convertible notes payable for the same amount in cash, at which time the notes were cancelled. In connection with the repayment, the parties agreed that the Company was no longer required to pay accrued interest associated with the notes payable in the amount of $~~49,983. As a result, the Company recognized a gain on forgiveness of accrued interest of $49,983~~ ~~on its condensed consolidated statement of operations during the six months ended June 30, 2021.~~

~~On April 27, 2021, the Company amended the following terms of two convertible notes in the aggregate principal amount of $150,000: (i) the maturity dates were extended to~~ ~~October 15, 2021, (ii) the interest rate was amended from~~ 8~~% per annum to~~ 10% per annum and (iii) the shares into which the notes may be converted was amended from Series B Preferred Stock to Series C Preferred Stock. The Company determined the amendment represented a debt modification.

~~During the six months ended June 30, 2021, the Company paid $100,000~~ ~~to a noteholder as a partial repayment of principal such that the note had $150,000~~ ~~outstanding as of June 30, 2021 after the partial repayment.~~

~~See Note 8,~~ ~~Commitments and Contingencies – Litigation~~ ~~for details associated with the partial repayment of a note payable during the six months ended June 30, 2021.~~

During the three months ended ~~June 30,~~March 31, 2022 and 2021, ~~and 2020,~~ the Company accrued additional preferred dividends related to Series A and Series C Convertible Preferred Stock of $~~225,873~~ 324,917and $~~211,885~~223,391~~, respectively. During the six months ended June 30, 2021 and 2020, the Company accrued additional preferred dividends of $449,264~~ ~~and $423,190~~, respectively.

~~During the three months ended June 30, 2021, the Company issued~~ Series C Convertible Preferred Stock

See Note 5, Notes Payable – Convertible Notes Payable for details associated with conversions of notes payable into 183,422 shares of Series C Convertible Preferred Stock.

See Note 5, Notes Payable – Convertible Notes Payable for details associated with conversions of accrued interest into 76,530shares of common ~~stock at the stated value of $0.75~~ ~~per share for aggregate value of $474,475, pursuant to the terms of the Series A Convertible Preferred Stock Certificate of Designation, in connection with the partial payment of accrued dividends for Series A Convertible Preferred Stock.~~stock.

~~On January 5, 2021, the Company issued~~ ~~125,000~~ ~~five-year immediately vested warrants to a note holder in satisfaction of certain noteholder rights with an exercise price $0.95~~ ~~per share. The warrant had an issuance date fair value of $33,545~~ ~~which was recognized immediately.~~

~~During the six months ended June 30, 2021, the Company issued~~ ~~125,071~~ ~~shares of common stock pursuant to a cashless warrant exercise by a noteholder of warrants to purchase~~ ~~221,275~~ ~~shares of common stock at an exercise price of $0.75~~ ~~per share.~~

See Note 5, Notes Payable for additional details associated with the issuance of stock warrants.

~~On March 8, 2021, the Company granted~~ ~~1,350,000~~ ~~five-year immediately vested options under the Company’s Equity Incentive Plan to the Chief Executive Offer of the Company (of which,~~ ~~750,000~~ ~~were granted for service as Chief Executive Officer and~~ ~~600,000~~ ~~were granted for service as a director) with an exercise price $1.00~~ ~~per share. The options had a grant date fair value of $218,600~~ ~~which was recognized during the six months ended June 30, 2021.~~

During the three months ended ~~June 30, 2021, the Company issued~~ ~~5,405~~ ~~shares of immediately vested common stock to a service provided with a grant date fair value of $2,540~~ ~~which was recognized immediately.~~

~~During the three months ended June 30, 2021,~~March 31, 2022, the Company recognized stock-based compensation expense of $~~45,972~~ 4,960~~(consisting~~ (consisting of $~~36,335~~ 5,372of expense related to warrants ~~(of which, $36,326~~ ~~has been included within stockholder’s deficiency~~ and $9 ~~has been included within accrued compensation) and $9,637~~(412) of expense related to common stock which has been included $~~7,097~~within accrued ~~compensation and $2,540included within stockholder’s deficiency)~~compensation) which was included within general and administrative expenses.

During the ~~six~~three months ended ~~June 30,~~March 31, 2021, the Company recognized stock-based compensation expense of $~~283,744~~ 237,772~~(consisting~~ (consisting of $~~67,707~~ 31,372of expense related to warrants (of which, $~~67,619~~ 31,276has been included within ~~stockholder’s~~stockholders’ deficiency and $8896 has been included within accrued compensation), and $206,400of expense related to options ~~which has been included~~(included within stockholder’s ~~deficiency and $9,637~~ ~~of expense related to common stock which has been included $7,097within accrued compensation and $2,540~~ ~~included within stockholder’s~~ deficiency), which was included within general and administrative expenses.

~~During the three and six months ended June 30, 2020, the Company recognized stock-based compensation expense of $332,894~~ ~~and $337,422, respectively, related to common stock and warrants, which amounts were included within general and administrative expenses on the condensed consolidated statements of operations.~~

~~As of June 30, 2021, there~~ There was $~~72,281~~ noof unrecognized stock-based compensation expense ~~to be recognized over a weighted average period~~as of ~~0.50~~ ~~years.~~March 31, 2022.

As of ~~June 30, 2021~~March 31, 2022 and December 31, ~~2020,~~2021, the Company was required to issue warrants to purchase an aggregate of ~~1,206,500~~ 1,431,500and ~~1,056,500~~1,356,500, respectively, shares of common stock at an exercise price of $0.75per share to directors of the Company in connection with loans made to the Company in the aggregate amount of $459,000which required certain penalties in the form of warrants. As a result, the Company had accrued $~~337,264~~ 269,194and $~~291,708~~ 249,389associated with the fair value of the obligations as of ~~June 30, 2021~~March 31, 2022 and December 31, ~~2020,~~2021, respectively, which amount is included in accrued interest – related parties on the condensed consolidated balance sheets.

See Note 5, Notes Payable – Convertible Notes Payable – Related Parties for details of the issuance of a convertible note to a director of the Company.

During the three months ~~June 30,~~March 31, 2022 and 2021, ~~and 2020,~~ the Company recorded research and development expenses of approximately $~~12,500~~ 14,500and $~~50,000~~35,000, respectively, related to its Research and License Agreement with Yeda (the “Agreement”). ~~During the six months June 30, 2021 and 2020, the Company recorded research and development expenses of approximately $48,000 and $112,000, respectively, related to the Agreement.~~ As of ~~June 30, 2021~~March 31, 2022 and December 31, ~~2020,~~2021, the Company had ~~$26,919 and $136,919, respectively,~~$0 of accrued research and development expenses pursuant to the Agreement with ~~Yeda, which are included within current liabilities on the condensed consolidated balance sheets.~~Yeda.

The Company recognized $~~313,384~~ 429,505and $~~124,926~~ 200,764of research and development expenses during the three months ended ~~June 30, 2021~~March 31, 2022 and ~~2020, respectively, and $514,148~~ ~~and $362,471~~ ~~of research and development expenses during the~~ ~~six months ended June 30,~~ 2021,~~and 2020,~~ respectively, associated with services provided by The University of Texas M.D. Anderson Cancer Center (“MD Anderson”) under the two agreements with MD Anderson dated November 2018 and February 2019, respectively. As of ~~June 30, 2021~~March 31, 2022 and December 31, ~~2020,~~2021, the Company had $0 316,514and $~~462,785~~411,773, respectively, of accrued research and development expenses pursuant to the agreements with MD Anderson. ~~As of June 30, 2021, the Company had prepaid research costs of approximately $200,000~~ ~~related to research to be performed during the three months ended September 30, 2021.~~

Certain conditions may exist as of the date the condensed consolidated financial statements are issued, which may result in a loss to the Company, but which will only be resolved when one or more future events occur or fail to occur. The Company assesses such contingent liabilities, and such assessment inherently involves an exercise of judgment. In assessing loss contingencies related to legal proceedings that are pending against the Company, or unasserted claims that may result in such proceedings, the Company evaluates the perceived merits of any legal proceedings or unasserted claims, as well as the perceived merits of the amount of relief sought or expected to be sought therein.

If the assessment of a contingency indicates that it is probable that a material loss has been incurred and the amount of the liability can be estimated, then the estimated liability would be accrued in the Company’s condensed consolidated financial statements. If the assessment indicates that a potential material loss contingency is not probable, but is reasonably possible, or is probable but cannot be estimated, then the nature of the contingent liability and an estimate of the range of possible losses, if determinable and material, would be disclosed.

In January 2019, the holder of a promissory note in the principal amount of $250,000 due on March 16, 2016 instituted a collection action in the Supreme Court of the State of New York, County of New York. AOn June 12, 2019, the plaintiff served a motion for summary judgment through the Secretary of State which was heard on July 12, 2019 and granted. The Company contends that it was not given sufficient notice under the ~~Company~~applicable statute and did not have an opportunity to oppose the motion. Judgment was entered in October 2019 in the amount of $267,680, which includes the principal amount due under the promissory note plus additional penalties and ~~the Company’s~~interest. The Company brought a motion to vacate based on the jurisdictional defect of the motion in not providing the required amount of time, but that motion was denied in February ~~2021.~~2021 without properly addressing the jurisdictional issues raised by the Company. The Company has appealed the denial and ~~is vigorously pursuing~~then filed a motion to ~~renew~~Renew and ~~reargue~~Reargue the motion to vacate ~~so that it can present factual defenses~~based on the Court’s failure to address critical issues. That motion was also denied on April 15, 2021 without addressing the ~~plaintiff’s claims.~~ Company’s arguments. The Company appealed both denials and the appeal was denied. While the Company’s motions were pending, the plaintiff has commenced steps to collect judgment. During the ~~three months~~year ended ~~June 30,~~December 31, 2021, $~~99,588~~ $103,088 was released to an officer of the court and has been accounted for as partial note repayment, such that, as of ~~June 30, 2021,~~March 31, 2022, there was $~~150,412~~ $146,912 outstanding under the note. ~~Subsequent to June 30,~~During the year ended December 31, 2021, a third party, on behalf of the Company, ~~a third party~~ deposited the ~~full amount of the~~remaining unpaid ~~judgment~~judgement with the court, which will be used to resolve the ~~matter in the event of an adverse outcome.~~underlying note.

Loss contingencies considered remote are generally not disclosed, unless they involve guarantees, in which case the guarantees would be disclosed. There can be no assurance that such matters will not materially and adversely affect the Company’s business, financial position, and results of operations or cash flows. AsAside from the matters discussed elsewhere in this note and Note 9, Subsequent Events- Litigation, there are no other known contingencies through the date of ~~June 30, 2021 and December 31, 2020, the Company had not accrued any amounts for contingencies.~~this filing.

The Company has evaluated events that have occurred after the balance sheet and through the date the financial statements were issued. Based upon the evaluation, the Company did not identify any recognized or non-recognized subsequent events that would have required adjustment or disclosure in the financial statements, except as disclosed below.

~~On July 26, 2021, the Company’s Board of Directors approved the designation of~~ ~~500,000~~ ~~shares of the~~ ~~10,000,000~~ ~~authorized shares of preferred stock as Series C Convertible Preferred Stock, par value $0.001~~ ~~per share. On July 27, 2021, the Company filed the Certificate of Designation with the State of Nevada related to the Series C Preferred Stock. The Series C Preferred stock has a stated value of $7.50~~ ~~per share.~~

~~Conversion.~~ Each share of Series C Preferred Stock is convertible into shares of common stock (subject to adjustment as provided in the related certificate of designation of preferences, rights and limitations) at the option of the holder at any time. The number of shares of common stock which are issuable upon conversion of the Series C Preferred Stock shall be equal to the number of shares of Series C Preferred Stock to be converted, multiplied by the stated value of $~~7.50~~ ~~per share, divided by the conversion price in effect at the time of conversion, initially at $0.75~~ ~~per share.~~

~~Mandatory Conversion.~~ On the earlier of (i) July 27, 2025 or (ii) any of the Company’s treatment candidates receiving approval from the U.S. or European agencies, all of the outstanding shares of Series C Preferred Stock will automatically convert to common stock.

~~Liquidation Preference.~~ In the event of the liquidation, dissolution or winding-up of the Company, the Series C Preferred Stock will rank senior to common stock and any other class of capital stock which does not expressly rank senior to or pari passu with the Series C Preferred Stock and will rank pari passu with the Series A and Series B Preferred Stock.

~~Voting Rights.~~The holders of Series C Preferred Stock have the right to vote on any matter submitted to a vote of holders of common stock, voting together with the common stock as one class, on an as-converted basis.

~~Dividends.~~~~Holders of shares of Series C Preferred Stock will be entitled to receive cumulative dividends at an annual rate of~~ 8% of the stated value. Dividends are payable semi-annually on June 30 and December 31, commencing on December 31, 2022, either by (i) issuance of shares of common stock at the rate of $0.75 per share of common stock or (ii) in cash.

Subsequent to ~~June 30, 2021,~~March 31, 2022, the Company issued convertible notes payable in the aggregate principal amount of $~~802,500~~300,000 which have maturity dates ranging from ~~January 8,~~October 1, 2022through February ~~10, 2022~~11, 2023. The notes accrue interest at 8% per annum and are convertible at any time at the option of the holder into the Company’s Series C Convertible Preferred Stock at a conversion price of $7.50 per share. The notes ~~shall be become convertible at (i) the holder’s option, beginning on the date that the Company first issues any shares of its~~automatically convert into Series C Convertible Preferred Stock ~~or (ii) automatically~~ on the maturity date. In connection with the ~~issuance of the convertible notes,~~issuances, the Company issued ~~five-year~~five-year immediately vested warrants to purchase an aggregate of ~~642,000~~240,000 shares of common stock at an exercise price $1.25 per share.

Subsequent to March 31, 2022, Mr. Verstraete, advanced the Company an additional $1,000,000 under a convertible promissory note dated March 10, 2022.

Additionally, subsequent to March 31, 2022, the Company and Ms. Soave entered into an agreement to amend a previously issued convertible note dated October 28, 2019 in the aggregate principal amount of up to $6,000,000, whereby the maturity date of the note was extended to April 28, 2023.

See Note 5, Notes Payable – Convertible Notes Payable – Related Parties for additional details.

Subsequent to March 31, 2022, the Company issued a note payable in the principal amount of $168,093 which has a maturity date of June ~~30, 2021,~~16, 2022. The note accrues interest at 10% per annum and the interest shall be payable, at the Company’s election, either in cash or in common stock at $0.75 per share. In connection with the ~~designation~~issuance, the Company issued a five-year immediately vested warrant to purchase 200,000 shares of common stock at an exercise price $0.75 per share.

Subsequent to March 31, 2022, the Company issued 796,629 shares of common stock at $0.75 per share in satisfaction of $597,472 of dividends payable on shares of Series A and Series C Convertible Preferred ~~Stock,~~Stock.

Subsequent to March 31, 2022, an aggregate of $~~1,262,223~~355,000 of principal outstanding under convertible notes automatically converted into an aggregate of ~~168,295~~ 47,333 shares of Series C Convertible Preferred Stock at a conversion price of $7.50 per share and the Company elected to pay an aggregate of $~~53,936~~14,014 of interest accrued under such notes by the issuance of an aggregate of ~~71,915~~ 18,684shares of common ~~stock. The aggregate note principal had a conversion price of~~ ~~$7.50~~ ~~per share and the common~~ stock ~~was valued~~ at $$0.75 per ~~share for purposes of the interest payment.~~share.

In August ~~2021,~~2022, a holder of 360,000 shares of the Company’s common stock filed a complaint against the Company, ~~extended~~its President and legal counsel in the ~~expiration date~~United States District Court, Southern District of New York, claiming unspecified damages for an alleged wrongful refusal to authorize the Company’s transfer agent to remove restrictive legends from the shares held by the shareholder. The Company has filed a ~~warrant~~motion to dismiss the complaint which is pending. The complaint against the Company’s legal counsel was dismissed by the Court and the Company’s President has not been served.

Subsequent to March 31, 2022, the Company granted five-year immediately vested stock options to purchase an aggregate of ~~75,000~~750,000 shares of common stock at an exercise price of $~~0.75~~1.00 per share ~~from August 4, 2021~~ to ~~August 4, 2025 and extended~~two directors of the ~~expiration date of a warrant to purchase~~ ~~37,500~~ ~~shares of common stock at an exercise price of $0.75~~ ~~per share from August 26, 2021 to August 26, 2025.~~Company.

~~Subsequent to June 30, 2021, the Company issued an aggregate of~~ ~~165,099~~ ~~shares of common stock to consultants.~~

Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations.

The following discussion and analysis of the condensed consolidated results of operations and financial condition of Cell Source, Inc. (“CSI”, “Cell Source”, the “Company”, “us,” “we,” “our,”) as of ~~June 30, 2021~~March 31, 2022 and for the three ~~and six~~ months ended ~~June 30,~~March 31, 2022 and 2021 ~~and 2020~~ should be read in conjunction with our unaudited financial statements and the notes thereto included elsewhere in this Quarterly Report on Form 10-Q and with our audited financial statements and the notes thereto included in our Annual Report on Form 10-K for the year ended December 31, ~~2020~~2021 as filed with the Securities and Exchange Commission (“SEC”) on April 15, ~~2021.~~2022.

This Quarterly Report contains forward-looking statements as that term is defined in the federal securities laws. The events described in forward-looking statements contained in this Quarterly Report may not occur. Generally, these statements relate to business plans or strategies, projected or anticipated benefits or other consequences of our plans or strategies, projected or anticipated benefits from acquisitions to be made by us, or projections involving anticipated revenues, earnings or other aspects of our operating results. The words “may,” “will,” “expect,” “believe,” “anticipate,” “project,” “plan,” “intend,” “estimate,” and “continue,” and their opposites and similar expressions, are intended to identify forward-looking statements. We caution you that these statements are not guarantees of future performance or events and are subject to a number of uncertainties, risks and other influences, many of which are beyond our control, which may influence the accuracy of the statements and the projections upon which the statements are based. Factors that may affect our results include, but are not limited to, the risks and uncertainties discussed in Item 1A (“Risk Factors”) of our Annual Report on Form 10-K for the year ended December 31, ~~2020,~~2021, filed with the SEC on April 15, ~~2021.~~2022.

We are a cell therapy company focused on immunotherapy. Since our inception, we have been involved with the development of proprietary immune system management technology licensed from Yeda Research & Development Company Limited (“Yeda”), the commercial arm of the Weizmann Institute. We have ~~recently~~since shifted the focus of our research and development efforts to MD Anderson.

This technology addresses one of the most fundamental challenges within human immunology: how to tune the immune response such that it tolerates selected desirable foreign cells, but continues to attack all other (undesirable) targets. In simpler terms, a number of potentially life-saving treatments have limited effectiveness today because the patient’s immune system rejects them. For example, while HSCT -– hematopoietic stem cell transplantation (e.g. bone marrow transplantation) has become a preferred therapeutic approach for treating blood cell cancer, most patients do not have a matched family donor. Although matched unrelated donors and cord blood can each provide an option for such patients, haploidentical stem cell transplants (sourced from partially mismatched family members) are rapidly gaining favor as a treatment of choice. This is still a risky and difficult procedure primarily because of potential conflicts between host (recipient) and donor immune systems and also due to viral infections that often follow even successful HSCT while the compromised new immune system works to reconstitute itself by using the transplanted stem cells. Today, rejection is partially overcome using aggressive immune suppression treatments that leave the patient exposed to many dangers by compromising their immune system.

The unique advantage of Cell Source technology lies in the ability to induce sustained tolerance of transplanted cells (or organs) by the recipient’s immune system in a setting that requires only mild immune suppression, while avoiding the most common post-transplant complications. The scientific term for the result of successfully inducing such tolerance in a transplantation setting is chimerism, where the recipient’s immune system tolerates the co-existence of the (genetically different) donor type and host ~~(recipient)~~ type cells. Attaining sustained chimerism is an important ~~perquisite~~prerequisite to achieving the intrinsic GvL (graft versus leukemia) effect of HSCT and supporting the reconstitution of normal hematopoiesis (generation of blood cells, including those that protect healthy patients from cancer) in blood cancer patients. Preclinical data and initial clinical data show that Cell Source’s Veto Cell technology can provide superior results in allogeneic (donor-derived) HSCT by allowing for haploidentical stem cell transplants under a mild conditioning regimen, while avoiding the most common post-transplant complications. Combining this with CAR (Chimeric Antigen Receptor) T cell therapy as a unified VETO CAR-T treatment, we will be able to treat patients in relapse as well as those in remission and use the cancer killing power of CAR-T to protect the patient while their immune system fully reconstitutes, thus providing an end-to-end solution for blood cancer treatment by potentially delivering a fundamentally safer and more effective allogeneic HSCT: prevention of relapse; avoidance GvHD; prevention of viral infections; and enhanced persistence of GvL effect. This means that the majority of patients will be able to find a donor, and will have access to a potentially safer procedure with higher long term survival rates than what either donor-derived HSCT or autologous CAR-T each on their own currently provide.

The ability to induce permanent chimerism (and thus sustained tolerance) in patients – which allows the transplantation to overcome rejection without having to compromise the rest of the immune system -– may open the door to effective treatment of a number of severe medical conditions, in addition to blood cancers, which are characterized by this need. These include:

Other than our Chief Executive Officer, we currently do not have any full-time employees, but retain the services of independent contractors/consultants on a contract-employment basis.

After two years of intensive collaboration with Professor Zelig Eshhar, the inventor of CAR-T cell therapy, ~~interim~~ data confirmed that Veto Cells can markedly extend persistence of genetically modified T cells from the same donor and that genetically modified Veto Cells can effectively inhibit tumors expressing an antigen recognized by the transgenic T cell receptor. Furthermore, human Veto Cells transfected with CAR exhibit anti-tumor activity in-vitro without losing their veto activity. These preclinical results ~~will~~ form the basis of ~~the~~our current development of a clinical protocol for allogeneic VETO CAR-T HSCT combined therapy for blood cancer treatment. Cell Source plans to submit this protocol for approval ~~by the end of 2021.~~in 2022. The Phase ~~1/2~~½ clinical trial at the University of Texas MD Anderson Cancer Center, using Cell Source’s Anti-viral Veto Cells, has successfully completed the first treatment cohort, with 3 patients each receiving a haploidentical HSCT under reduced intensity conditioning with Veto Cells. This first in human dose optimization trial has thus far shown that the initial dose is in fact the optimal dose, as all three patients had successful stem cell engraftment after 42 days, in the absence of GvHD. Cell Source is now continuing the trial as it proceeds with the ~~next cohort~~subsequent cohorts of patients, using the same dose level.

On May 6, 2022, Itamar Shimrat resigned his position as a director of the Company. Mr. Shimrat’s resignation was not the result of any disagreement with the Company and he will continue in his positions as President and Chief Executive Officer. Mr. Shimrat’s resignation as director follows an evaluation of the structure of the Board of Directors and a determination that it is in the best interest of the Company to have a Board of Directors comprised of an odd number of members to reduce the possibility of a deadlock.

On July 18, 2022, each of Ben Friedman and David Zolty resigned his position as a director of the Company. Neither Mr. Friedman’s nor Mr. Zolty’s resignation was the result of any disagreement with the Company.

~~Recently,~~The novel coronavirus (“COVID-19”) pandemic continues to impact global economic conditions. The Company is closely monitoring the outbreak of COVID-19 and its impact on the ~~novel coronavirus, or COVID-19, around~~Company’s operations, financial position, cash flows and its industry in general. The Company considered the ~~world has adversely impacted global commercial activity and contributed to significant volatility in financial markets and disrupted normal business operations. The global~~ impact of ~~the outbreak has been rapidly evolving,~~COVID-19 on its business and ~~many countries have reacted by instituting quarantines~~operational assumptions and ~~restrictions on travel,~~estimates, and many businesses and other institutions have temporarily closed or reduced work activities at their facilities. Such actions are creating disruption in global supply chains, and adversely impacting a number of industries, such as transportation, hospitality and entertainment. The outbreak could have a continued adverse impact on economic and market conditions and trigger a period of global economic slowdown. The rapid development and fluidity of this situation precludes any prediction as to the ultimate adverse impact of the novel coronavirus. Nevertheless, the novel coronavirus presents material uncertainty and its disruption of the capital markets may have adetermined there were no material adverse ~~impact~~impacts on ~~our ability to raise additional capital~~the Company’s condensed consolidated results of operations and ~~may slow down the pace at which research and clinical trials may be conducted on our behalf.~~financial position as of March 31, 2022.

~~Designation~~Similarly, the economic uncertainty caused by the COVID-19 pandemic has made and may continue to make it difficult for the Company to forecast operating results, including the timing and ability of ~~Series C Convertible Preferred Stock~~the Company to initiate and/or complete current and/or future preclinical studies and/or clinical trials, disrupt the Company’s regulatory activities, and/or have other adverse effects on the Company’s clinical development. The duration and extent of the impact from the COVID-19 pandemic depend on future developments that cannot be accurately predicted at this time, and if the Company is not able to respond to and manage the impact of such events effectively, the Company’s business may be harmed.

~~On July 26, 2021,~~There can be no assurance that precautionary measures, whether adopted by the Company or imposed by others, will be effective, and such measures could negatively affect the Company’s ~~Board~~condensed consolidated financial condition, cash flows, and results of Directors approved the designation of 500,000 shares of the 10,000,000 authorized shares of preferred stock as Series C Convertible Preferred Stock, par value $0.001 per share. On July 27, 2021, the Company filed the Certificate of Designation with the State of Nevada related to the Series C Preferred Stock.operations. The ~~Series C Preferred stock has a stated value of $7.50 per share.~~

~~Conversion.~~ Each share of Series C Preferred Stock is convertible into shares of common stock (subject to adjustment as provided in the related certificate of designation of preferences, rights and limitations) at the option of the holder atfinancial statements do not include any time. The number of shares of common stock which are issuable upon conversion of the Series C Preferred Stock shall be equal to the number of shares of Series C Preferred Stock to be converted, multiplied by the stated value of $7.50 per share, divided by the conversion price in effect at the time of conversion, initially at $0.75 per share.

~~Mandatory Conversion.~~ ~~On the earlier of (i) July 27, 2025 or (ii) any of the Company’s treatment candidates receiving approval~~adjustments that might result from the ~~U.S. or European agencies, all~~outcome of ~~the outstanding shares of Series C Preferred Stock will automatically convert to common stock.~~this uncertainty.

~~Liquidation Preference.~~ In the event of the liquidation, dissolution or winding-up of the Company, holders of Series C Preferred Stock will rank senior to common stock and any other class of capital stock which does not expressly rank senior to or pari passu with the Series C Preferred Stock and will rank pari passu with the Series A and Series B Preferred Stock.

~~Voting Rights.~~ The holders of Series C Preferred Stock have the right to vote on any matter submitted to a vote of holders of common stock, voting together with the common stock as one class, on an as-converted basis.

~~Dividends.~~ Holders of shares of Series C Preferred Stock will be entitled to receive cumulative dividends at an annual rate of 8% of the stated value. Dividends are payable semi-annually on June 30 and December 31, commencing on December 31, 2022, either by (i) issuance of shares of common stock at the rate of $0.75 per share of common stock or (ii) in cash.

Three Months Ended ~~June 30, 2021~~March 31, 2022 Compared with the Three Months Ended ~~June 30, 2020~~March 31, 2021

Research and development expense was ~~$367,551~~$479,005 and ~~$209,926~~$271,239 for the three months ended ~~June 30,~~March 31, 2022 and 2021, ~~and 2020,~~ respectively, aan increase of ~~$157,625,~~$207,766, or ~~75%~~77%. ~~The~~This increase ~~was primarily~~is attributable to ~~a milestone reached~~increased quarterly payments under the sponsored research agreement with MD Andersen. Furthermore, we enrolled an additional patient during the ~~second quarter of 2021~~2022 period which resulted in ~~additional~~research and development expense being recognized ~~related~~in the 2022 period. We anticipate reaching an enrollment level that will requires us to ~~our agreement with~~make a milestone payment to MD ~~Anderson.~~Andersen during fiscal 2022.

General and administrative expense, which is associated with external consulting and professional fees, payroll and stock-based compensation expenses, was ~~$627,548~~$573,667 and ~~$693,405~~$850,117 for the three months ended ~~June 30,~~March 31, 2022 and 2021, ~~and 2020,~~ respectively, a decrease of ~~$65,857,~~$276,450, or 9%33%. ~~Such~~The decrease was ~~primarily attributable~~due to ~~decreased~~a reduction in consulting and other professional fees during the ~~2021~~2022 period.

Interest expense for the three months ended ~~June 30,~~March 31, 2022 and 2021 was $166,765 and ~~2020 was $162,845 and $93,879,~~$280,887, respectively, ~~an increase~~a decrease of ~~$68,966,~~$114,122, or ~~73%~~41%. The ~~increase~~decrease was ~~primarily a result of increases in convertible~~due to less interest-bearing notes ~~payable~~ outstanding during the ~~2021 period as well as the fair value of warrants issued as interest.~~period.

Amortization of debt discount was ~~$155,169~~$73,138 and ~~$36,228~~ $122,763 for the three months ended ~~June 30,~~March 31, 2022 and 2021, ~~and 2020,~~ respectively, ~~an increase~~a decrease of ~~$118,941,~~$49,625, or ~~328%~~40%. ~~The increase~~This decrease is primarily associated with ~~increased levels~~a decreased amount and fair value of warrants ~~and common stock~~ issued ~~as debt discounts~~ in connection with convertible notes payable ~~in the 2021 period.~~

~~During the three months ended June 30, 2021 and 2020, we recognized $0 and $131,250 of loss on extinguishment of notes payable.~~

~~Six Months Ended June 30, 2021 Compared with the Six Months Ended June 30, 2020~~

Research and development expense was $638,790 and $529,138 for the six months ended June 30, 2021 and 2020, respectively, an increase of $109,652, or 21%. The increase was primarily attributable to a milestone reached during the ~~second quarter of 2021 which resulted in additional expense recognized related to our agreement with MD Anderson.~~

General and administrative expense, which is associated with external consulting and professional fees, payroll and stock-based compensation expenses, was $1,477,665 and $1,107,525 for the six months ended June 30, 2021 and 2020, respectively, an increase of $370,140, or 33%. The increase was primarily related to additional expenses recognized in the 2021 period as follows: approximately $78,000 of insurance expense, approximately $189,000 of legal fees, and $126,000 in accounting fees, partially offset by a decrease in other professional fees.

Interest expense for the six months ended June 30, 2021 and 2020 was $443,732 and $181,528, respectively, an increase of $262,204, or 144%. The increase was primarily a result of increases in convertible notes payable outstanding during the 2021 period as well as the fair value of warrants issued as interest.

Amortization of debt discount was $277,932 and $44,530 for the six months ended June 30, 2021 and 2020, respectively, an increase of $233,402, or 524%. The increase is primarily associated with increased levels of warrants and common stock issued as debt discounts in connection with convertible notes payable in the 20212022 period.

During the ~~six~~three months ended ~~June 30,~~March 31, 2021, we recognized a gain on forgiveness of accrued interest of $49,983 in connection with the repayment of certain notes payable.

The change in fair value of derivative liabilities for the six months ended June 30, 2020 was a gain of $16,977 due to the reduction in fair value of warrants and conversion options as a result of drawing closer to their expiration dates.

During the ~~six~~three months ended ~~June 30,~~March 31, 2021, ~~and 2020,~~ we recognized $49,718 ~~and $132,691~~ of loss on extinguishment of notes payable in connection with the extension and repayment of notes payable.

During the ~~six~~three months ended ~~June 30, 2021,~~March 31, 2022, we had not generated any revenues, had a net loss of approximately ~~$2,838,000~~$1,293,000 and had used cash in operations of approximately ~~$2,258,000.~~$1,028,000. As of ~~June 30, 2021,~~March 31, 2022, we had a working capital deficiency of approximately ~~$10,030,000~~$9,997,000 and an accumulated deficit of approximately ~~$28,544,000. Subsequent to June 30, 2021, we received proceeds~~$32,471,000. As of ~~$575,000~~March 31, 2022 and through the ~~issuance~~date of ~~convertible~~this filing, notes ~~payable.~~payable with principal amounts totaling $1,554,912 and $1,408,000, respectively were past due and are classified as current liabilities on the condensed consolidated balance sheet as of March 31, 2022. We will continue to incur net operating losses to fund operations. These conditions raise substantial doubt about our ability to continue as a going concern for at least one year from the date these financial statements are issued. Subsequent to March 31, 2022, we received aggregate proceeds of $150,000 from the issuance of convertible notes payable.

We are currently funding our operations on a month-to-month basis. Our ability to continue our operations is dependent on the execution of management’s plans, which include the raising of capital through the debt and/or equity markets, until such time that funds provided by operations are sufficient to fund working capital requirements. We may need to incur additional liabilities with certain related parties to sustain our existence. If we were not to continue as a going concern, we would likely not be able to realize our assets at values comparable to the carrying value or the fair value estimates reflected in the balances set out in the preparation of our financial statements.

There can be no assurances that we will be successful in generating additional cash from equity or debt financings or other sources to be used for operations. Should we not be successful in obtaining the necessary financing to fund our operations, we would need to curtail certain or all operational activities and/or contemplate the sale of our assets, if necessary.

During the ~~six~~three months ended ~~June 30,~~March 31, 2022 and 2021, ~~and 2020,~~ our sources and uses of cash were as follows:

We experienced negative cash flows from operating activities for the ~~six~~three months ended ~~June 30,~~March 31, 2022 and 2021 ~~and 2020~~ in the amounts of approximately ~~$2,258,000~~$1,028,000 and ~~$1,154,000,~~$1,114,000, respectively. The net cash used in operating activities for the ~~six~~three months ended ~~June 30, 2021~~March 31, 2022 was primarily due to cash used to fund a net loss of approximately ~~$2,838,000,~~$1,293,000, adjusted for ~~net~~ non-cash expenses in the aggregate amount of approximately ~~$780,000, and~~$112,000, partially offset by $~~200,000~~153,000 of net cash ~~used in~~provided by changes in the levels of operating assets and liabilities. The net cash used in operating activities for the ~~six~~three months ended ~~June 30, 2020~~March 31, 2021 was primarily due to cash used to fund a net loss of approximately ~~$1,978,000,~~$1,525,000, adjusted for net non-cash expenses in the aggregate amount of approximately ~~$516,000, partially offset by $308,000~~$541,000, and $131,000 of net cash ~~provided by~~used in changes in the levels of operating assets and liabilities.

Net cash provided by financing activities for the ~~six~~three months ended ~~June 30,~~March 31, 2022 and 2021 ~~and 2020~~ was approximately ~~$2,098,000~~$1,067,000 and ~~$1,127,000,~~$972,000, respectively. The net cash provided by financing activities during the ~~six~~three months ended ~~June 30, 2021~~March 31, 2022 was attributable to ~~$2,422,250~~$1,000,000 of proceeds from the issuance of convertible notes to a related party director and $95,000 of proceeds from the issuance of convertible notes payable, partially offset by the repayments of the insurance financing liability in the amount of $28,000. The net cash provided by financing activities during the three months ended March 31, 2021 was attributable to approximately $1,197,000 of proceeds from the issuance of convertible notes payable, partially offset by the repayments of notes payable and convertible notes payable in the amount of $324,588. The net cash provided by financing activities during the six months ended June 30, 2020 was attributable to $1,075,000 of proceeds from the issuance of convertible notes payable, $125,000 of proceeds from the issuance of Series A preferred stock, $100,000 of proceeds from the issuance of notes payable and $100,000 of proceeds from advances payable, offset by the repayment of a note payable in the amount of $100,000, $105,000 of repayments of advances payable and a $68,000 repayment of a convertible note payable.$225,000.

The preparation of financial statements and related disclosures must be in conformity with U.S. GAAP. These accounting principles require us to make estimates and judgments that can affect the reported amounts of assets and liabilities as of the date of the financial statements as well as the reported amounts of revenue and expense during the periods presented. We believe that the estimates and judgments upon which it relies are reasonably based upon information available to us at the time that it makes these estimates and judgments. To the extent that there are material differences between these estimates and actual results, our financial results will be affected. The accounting policies that reflect our more significant estimates and judgments and which we believe are the most critical to aid in fully understanding and evaluating our reported financial results are described below.

The following is not intended to be a comprehensive list of all of our accounting policies or estimates. Our accounting policies are more fully described in Note 3 – Summary of Significant Accounting Policies, in our financial statements included elsewhere in this quarterly report.

The Company evaluates its convertible instruments to determine if those contracts or embedded components of those contracts qualify as derivative financial instruments to be separately accounted for in accordance with Topic 815 of the Financial Accounting Standards Board (“FASB”) Accounting Standards Codification (“ASC”). The accounting treatment of derivative financial instruments requires that the Company record embedded conversion options and any related freestanding instruments at their fair values as of the inception date of the agreement and at fair value as of each subsequent balance sheet date. Any change in fair value is recorded as non-operating, non-cash income or expense for each reporting period at each balance sheet date. The Company reassesses the classification of its derivative instruments at each balance sheet date. If the classification changes as a result of events during the period, the contract is reclassified as of the date of the event that caused the reclassification. Embedded conversion options and any related freestanding instruments are recorded as a discount to the host instrument and are amortized as interest expense over the term of the related debt instrument.

If the instrument is determined to not be a derivative liability, the Company then evaluates for the existence of a beneficial conversion feature by comparing the commitment date fair value to the effective conversion price of the instrument.

The Black-Scholes option pricing model was used to estimate the fair value of the Company’s warrants and embedded conversion options. The Black-Scholes option pricing model includes subjective input assumptions that can materially affect the fair value estimates. ~~The Company determined the fair value under the Binomial Lattice model and the Black-Scholes option pricing model to be materially the same.~~

~~Embedded conversion options within notes payable are recorded as a debt discount and are amortized as interest expense over the term of the related debt instrument.~~

The Company measures the fair value of financial assets and liabilities based on ASC 820 “Fair Value Measurements and Disclosures” (“ASC 820”), which defines fair value, establishes a framework for measuring fair value, and expands disclosures about fair value measurements.

ASC 820 defines fair value as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. ASC 820 also establishes a fair value hierarchy, which requires an entity to maximize the use of observable inputs and minimize the use of unobservable inputs when measuring fair value. ASC 820 describes three levels of inputs that may be used to measure fair value:

Level 1 — quoted prices in active markets for identical assets or liabilities;

Level 2 — quoted prices for similar assets and liabilities in active markets or inputs that are observable; and

Level 3 — inputs that are unobservable (for example, cash flow modeling inputs based on assumptions).

The carrying amounts of the Company’s financial instruments, such as cash, other current assets, accounts payable, accrued expenses and other current liabilities approximate fair values due to the short-term nature of these instruments. The carrying amounts of Company’s credit obligations approximate fair value because the effective yields on these obligations, which include contractual interest rates, are comparable to rates of returns for instruments of similar credit risk.

The Company measures the cost of services received in exchange for an award of equity instruments based on the fair value of the award. The fair value of the award is measured on the grant date and is then recognized over the period the services are required to be provided in exchange for the award, usually the vesting period. Awards granted to directors are treated on the same basis as awards granted to employees. Upon the exercise of an option or warrant, the Company issues new shares of common stock out of its authorized shares.

Because the Company’s common stock historically was not actively traded on a public market, the fair value of the Company’s restricted equity instruments is estimated by management based on observations of the sales prices of both restricted and freely tradable common stock, or instruments convertible into common ~~stock.~~stock based on the option pricing model discussed below. The Company obtained a third-party valuation of its common stock as of December 31, ~~2020,~~2021, which was considered in management’s estimation of fair value during the ~~six~~three months ended ~~June 30, 2021.~~March 31, 2022. The third-party valuation was performed in accordance with the guidance outlined in the American Institute of Certified Public Accountants’ Accounting and Valuation Guide, Valuation of Privately-Held-Company Equity Securities Issued as Compensation. The estimates used by management are considered highly complex and subjective. The Company anticipates that once its shares become more actively traded, the use of such estimates will no longer be necessary to determine the fair value of its common stock.

The ~~December 2020~~ independent ~~appraisal~~appraisals utilized the option pricing method, or OPM, as the most reliable method with the following steps being applied:

Under the OPM, it was determined the Company’s common stock had a fair value of ~~$0.47~~$0.34 per share as of December 31, 2021, which included a discount for lack of marketability of 30%. Furthermore, the independent appraisal determined the Company’s expected volatility was 90% by evaluating historical and implied volatilities of guideline companies.

Disclosure controls are procedures that are designed with the objective of ensuring that information required to be disclosed in our reports filed under the Exchange Act, such as this Annual Report, is recorded, processed, summarized and reported within the time periods specified in the SEC’s rules and forms. Disclosure controls are also designed with the objective of ensuring that such information is accumulated and communicated to our management, including the Principal Executive and Financial Officer, as appropriate to allow timely decisions regarding required disclosure. Internal controls are procedures which are designed with the objective of providing reasonable assurance that (1) our transactions are properly authorized, recorded and reported; and (2) our assets are safeguarded against unauthorized or improper use, to permit the preparation of our condensed consolidated financial statements in conformity with United States generally accepted accounting principles.

In connection with the preparation of this Quarterly Report, management, with the participation of our Principal Executive and Financial Officer, has evaluated the effectiveness of the design and operation of our disclosure controls and procedures (as defined in Exchange Act Rule 13a-15(e) and 15d-15(e)). Based upon that evaluation, our Principal Executive and Financial Officer concluded that, as of ~~June 30, 2021,~~March 31, 2022, our disclosure controls and procedures were effective.

There were no changes in our internal control over financial reporting (as defined in Rule 13a-15(f) and 15d-15(f) under the Exchange Act) during the quarter ended ~~June 30, 2021~~March 31, 2022 that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

Except as described below, we are not involved in any pending legal proceeding or litigations and, to the best of our knowledge, no governmental authority is contemplating any proceeding to which we are a party or to which any of our properties is subject, which would reasonably be likely to have a material adverse effect on us.

In January 2019, the holder of a promissory note in the principal amount of $250,000 due on March 16, 2016 instituted a collection action in the Supreme Court of the State of New York, County of New York. AOn June 12, 2019, the plaintiff served a motion for summary ~~judgement~~judgment through the Secretary of State which was heard on July 12, 2019 and granted. The Company contends that it was not given sufficient notice under the ~~Company’s~~applicable statute and did not have an opportunity to oppose the motion. Judgment was entered in October 2019 in the amount of $267,680, which includes the principal amount due under the promissory note plus additional penalties and interest. The Company brought a motion to vacate based on the jurisdictional defect of the motion in not providing the required amount of time, but that motion was denied in February ~~2021.~~2021 without properly addressing the jurisdictional issues raised by the Company. The Company has appealed the denial and ~~is vigorously pursuing~~then filed a motion to ~~renew~~Renew and ~~reargue~~Reargue the motion to vacate ~~so that it can present factual defenses~~based on the Court’s failure to address critical issues. That motion was also denied on April 15, 2021 without addressing the ~~plaintiff’s claims.~~Company’s arguments. The Company appealed both denials and the appeal was denied. While the Company’s motions were pending, the plaintiff has commenced steps to collect judgment. During the ~~three months~~year ended ~~June 30,~~December 31, 2021, ~~$99,588~~$103,088 was released to an officer of the court and has been accounted for as partial note repayment, such that, as of ~~June 30, 2021,~~March 31, 2022, there was ~~$150,412~~$146,912 outstanding under the note. ~~Subsequent to June 30,~~During the year ended December 31, 2021, a third party, on behalf of the Company, ~~a third party~~ deposited the ~~full amount of the~~remaining unpaid ~~judgment~~judgement with the court, which will be used to resolve the ~~matter~~underlying note.

In August 2022, a holder of 360,000 shares of the Company’s common stock filed a complaint against the Company, its President and legal counsel in the ~~event~~United States District Court, Southern District of New York, claiming unspecified damages for an ~~adverse outcome.~~alleged wrongful refusal to authorize the Company’s transfer agent to remove restrictive legends from the shares held by the shareholder. The Company has filed a motion to dismiss the complaint which is pending. The complaint against the Company’s legal counsel was dismissed by the Court and the Company’s President has not been served.

There have been no material changes to the risk factors discussed in Item 1A. Risk Factors in our Annual Report on Form 10-K for the year ended December 31, ~~2020,~~2021, which was filed with the SEC on April 15, ~~2021.~~2022.

During the three months ended March 31, 2022 convertible notes in the aggregate principal amount of $1,375,698 automatically converted into 183,422 shares of our Series C Convertible Preferred Stock on the maturity dates of the convertible notes. We relied upon the exemption provided by Section 3(a)(9) of the Securities Act in connection with these transactions.

During the three months ended March 31, 2022 we issued an aggregate of 76,530 shares of our common stock to holders of convertible notes in lieu of cash interest upon the maturity of the notes. We relied upon the exception provided by Section 4(2) of the Securities Act in connection with these transactions.

During the three months ended March 31, 2022, we issued convertible notes in the aggregate principal amount of ~~$562,250~~$95,000 to three accredited investors. We issued an additional $150,000 aggregate principal amount of convertible notes to two accredited investors in April 2022. The notes mature six months from the date of issuance and accrue interest at a rate of eight percent (8%) per annum. The notes are convertible into shares of our Series C Preferred Stock at a conversion price of $7.50 per share at the holder’s option beginning on the date we first issue any shares of Series C Preferred Stock and automatically ~~convert into common stock~~ on the maturity date. ~~The~~It is anticipated that the Series C Preferred Stock will convert into shares of our common stock at a rate of ten shares of common stock for each share of Series C Preferred Stock. In connection with the issuance of the notes, we issued five year warrants to purchase an aggregate of ~~449,800~~196,000 shares of common stock at an exercise price of $1.25 per share. We relied upon the exemption provided by Section 4(2) of the Securities Act ~~of 1933, as amended (the “Securities Act”) in connection with these transactions.~~

In April 2021, we amended two convertible notes in the aggregate principal amount of $150,000 with maturity dates in April 2021 to extend the maturity dates by six months and to increase the interest rate from 8% per annum to 10% per annum. In addition, the conversion feature of the note was amended to change the shares into which the notes may be converted from Series B Preferred Stock to Series C Preferred Stock. ~~We relied upon the exemption provided by Section 3(a)(9) of the Securities Act~~ in connection with these transactions.

In June 2021, we issued 5,405 shares of immediately vested common stock to a service provider. We relied upon the exemption provided by Section 4(2) of the Securities Act in connection with this transaction.

In ~~June 2021,~~March 2022, we ~~received an additional $1,000,000 of proceeds under~~issued a ~~previously issued~~ convertible promissory note ~~by means of the payment by the lender of outstanding obligations to third parties. In June 2021, we amended and restated the convertible note and increased~~in the principal amount of up to $6,000,000. The note bears interest at a rate of 10% per annum and will mature twelve months from ~~$4,000,000~~the date of issuance. The holder has agreed to ~~$6,000,000 and~~ ~~in August 2021~~ issued a five year warrant to purchase a total of 800,000 shares of common stock at an exercise price of $1.25 per share to the lender in accordance with the terms of the convertible note. After giving effect to the $1,000,000 advance made in June 2021, the lender had advancedloan an aggregate of ~~$3,500,000~~$2,500,000 to us under the ~~convertible note. We may elect~~note and advanced $1,000,000 under the note in March 2022. The holder has the right, at his option, to convert the ~~amended and restated~~ note into shares of the Company’s Series B Convertible Preferred Stock at a conversion price of $7.50 per share at any time after the creation and sale of the Series B Convertible Preferred ~~Stock and before~~Stock. Interest accruing under the note will be payable upon the maturity ~~date. We~~of the note and may be paid at the Company’s option in either cash or shares of the Company’s common stock (valued at $0.75 for purposes of calculating the number of shares). For each $500,000 advanced under the note, the holder will be issued a warrant to purchase 400,000 shares of the Company’s Common Stock at an exercise price of $1.25 per share. The Company relied upon the ~~exemptions provided by Sections 3(a)(9) and Section 4(2) of the Securities Act in connection with these transactions.~~

~~On June 30, 2021, we issued 632,667 shares of common stock as payment of in-kind dividends to holders of Series A Convertible Preferred Stock. We relied upon the exception~~exemption provided by Section 4(2) of the Securities Act in connection with this transaction.

In August 2021, we extended the expiration date of a warrant to purchase 150,000 shares of our common stock at an exercise price of $0.75 per share from August 4, 2021 to August 4, 2025 and extended the expiration date of a warrant to purchase 37,500 shares of common stock at an exercise price of $0.75 per share from August 26, 2021 to August 26, 2025. We relied upon the exemption provided by Section 3(a)(9) of the Securities Act in connection with these transactions.

As of ~~June 30, 2021~~March 31, 2022 and through the date of this filing, notes payable and convertible notes payable with face values totaling ~~$1,933,412~~$1,554,912 and ~~$2,870,634,~~$1,408,000, respectively were past due and are classified as current liabilities on the condensed consolidated balance sheet as of ~~June 30, 2021.~~March 31, 2022. Such notes continue to accrue interest and all relevant penalties have been accrued as of ~~June 30, 2021.~~March 31, 2022. Of such past due notes payable, a holder of a note with principal amount of $250,000 issued a notice of default. See Item 1 above for additional details. We are in negotiations with all holders to extend the maturity dates of such notes or to convert the principal and accrued interest into equity.

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Title of each class		Trading symbol(s)		Name of each exchange on which registered
None		N/A		N/A

Large accelerated filer ☐		Accelerated filer ☐

Non-accelerated filer ☒	☒	Smaller reporting company ☒

		Emerging growth company ☐

PART I - FINANCIAL INFORMATION

Item 1.	Financial Statements.	3

	Condensed Consolidated Balance Sheets as of ~~June 30, 2021~~March 31, 2022 (Unaudited) and December 31, ~~2020~~2021	3

	Unaudited Condensed Consolidated Statements of Operations for the Three ~~and Six~~ Months Ended ~~June 30,~~March 31, 2022 and 2021 ~~and 2020~~	4

	Unaudited Condensed Consolidated Statements of Changes in Stockholders’ Deficiency for the ~~Six~~Three Months Ended ~~June 30,~~March 31, 2022 and 2021 ~~and 2020~~	5

	Unaudited Condensed Consolidated Statements of Cash Flows for the ~~Six~~Three Months Ended ~~June 30,~~March 31, 2022 and 2021 ~~and 2020~~	6

	Notes to Unaudited Condensed Consolidated Financial Statements	7

Item 2.	Management’s Discussion and Analysis of Financial Condition and Results of Operations.	14

Item 3.	Quantitative and Qualitative Disclosures About Market Risk.	2019

Item 4.	Controls and Procedures.	2019

PART II - OTHER INFORMATION

~~Item 1. Legal Proceedings.~~	21

Item ~~1A. Risk Factors.~~1.	Legal Proceedings.	2120

Item 1A.	Risk Factors.	20

Item 2.	Unregistered Sales of Equity Securities and Use of Proceeds.	2120

Item 3.	Defaults Upon Senior Securities.	2221

Item 4.	Mine Safety Disclosures.	2221

Item 5.	Other Information.	2221

Item 6.	Exhibits.	2221

	SIGNATURES	2322

		June 30, 2021			December 31, 2020
		June 30,			December 31,
		2021			2020
		(Unaudited)
Assets
Current Assets:
Cash	$	81,705		$	241,619
Prepaid expenses		215,264			177,569
Other current assets		8,067			29,651
Total Current Assets		305,036			448,839
Restricted cash		3,500			3,500
Total Assets	$	308,536		$	452,339

Liabilities and Stockholders’ Deficiency

Current Liabilities:
Accounts payable	$	339,990		$	193,095
Accrued expenses		695,955			1,159,950
Accrued expenses - related parties		88,701			198,701
Accrued interest		919,863			671,968
Accrued interest - related parties		372,320			325,276
Accrued compensation		749,337			724,185
Advances payable		195,500			195,500
Advances payable - related party		100,000			100,000
Notes payable		813,412			1,013,000
Notes payable - related parties		150,000			150,000
Convertible notes payable - current portion, net of debt discount of $279,105 and $157,720 as of June 30, 2021 and December 31, 2020, respectively		5,685,368			3,417,836
Convertible notes payable - related parties		225,000			225,000
Accrued dividend payable		-			25,210
Total Liabilities		10,335,446			8,399,721

Commitments and contingencies (Note 8)		-			-

Stockholders’ Deficiency:
Convertible Preferred Stock, $0.001 par value, 10,000,000 shares authorized;
Series A Convertible Preferred Stock, 1,335,000 shares designated, 1,342,195 shares issued and outstanding as of June 30, 2021 and December 31, 2020; liquidation preference of $10,066,463 and $10,091,672 as of June 30, 2021 and December 31, 2020, respectively		1,342			1,342
Series C Convertible Preferred Stock, 500,000 shares designated, 0 shares issued and outstanding as of June 30, 2021 and December 31, 2020; liquidation preference of $0 as of June 30, 2021 and December 31, 2020		-			-
Common Stock, $0.001 par value, 200,000,000 shares authorized; 33,301,564 and 32,538,411 shares issued and outstanding as of June 30, 2021 and December 31, 2020, respectively		33,301			32,538
Additional paid-in capital		18,482,294			17,724,731
Accumulated deficit		(28,543,847	)		(25,705,993	)
Total Stockholders’ Deficiency		(10,026,910	)		(7,947,382	)
Total Liabilities and Stockholders’ Deficiency	$	308,536		$	452,339


	March 31, 2022			December 31, 2021
	(Unaudited)
Assets
Current Assets:
Cash	$	131,999		$	93,095
Prepaid expenses		121,236			203,750
Other current assets		23,574			16,922
Total Assets	$	276,809		$	313,767

Liabilities and Stockholders’ Deficiency

Current Liabilities:
Accounts payable	$	332,859		$	223,041
Accrued expenses		918,568			1,097,021
Accrued expenses - related party		72,000			72,000
Accrued interest		523,972			532,960
Accrued interest - related parties		882,345			649,265
Accrued compensation		778,043			766,102
Notes payable		759,912			759,912
Notes payable - related parties		150,000			150,000
Convertible notes payable, net of debt discount of $12,756 and $71,124 as of March 31, 2022 and December 31, 2021, respectively		612,207			1,834,446
Convertible notes payable - related parties, net of debt discount of $108,126 and $0 as of March 31, 2022 and December 31, 2021, respectively		4,616,874			3,725,000
Advances payable		135,000			135,000
Advances payable - related party		100,000			100,000
Financing liability		-			27,926
Accrued dividend payable		392,146			67,229
Total Liabilities		10,273,926			10,139,902

Commitments and contingencies (Note 8)		-

Stockholders’ Deficiency:
Convertible Preferred Stock, $0.001 par value, 10,000,000 shares authorized; Series A Convertible Preferred Stock, 1,335,000 shares designated, 1,342,195 shares issued and outstanding as of March 31, 2022 and December 31, 2021, liquidation preference of $10,289,854 and $10,066,463 as of March 31, 2022 and December 31, 2021, respectively		1,342			1,342
Series C Convertible Preferred Stock, 500,000 shares designated, 455,443 and 272,021 shares issued and outstanding as of March 31, 2022 and December 31, 2021, respectively; liquidation preference of $3,584,578 and $2,107,388 as of March 31, 2022 and December 31, 2021, respectively		455			272
Preferred stock, value
Common Stock, $0.001 par value, 200,000,000 shares authorized; 34,437,076 and 34,360,546 shares issued and outstanding as of March 31, 2022 and December 31, 2021, respectively		34,437			34,361
Additional paid-in capital		22,437,652			21,316,318
Accumulated deficit		(32,471,003	)		(31,178,428	)
Total Stockholders’ Deficiency		(9,997,117	)		(9,826,135	)
Total Liabilities and Stockholders’ Deficiency	$	276,809		$	313,767

☒	QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

☐	TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

	Shares		Amount		Shares		Amount		Capital			Deficit			Deficiency
	FOR THE SIX MONTHS ENDED JUNE 30, 2021
	Convertible Preferred								Additional						Total
	Stock - Series A				Common Stock				Paid-In			Accumulated			Stockholders’
	Shares		Amount		Shares		Amount		Capital			Deficit			Deficiency

Balance, January 1, 2021		1,342,195	$	1,342		32,538,411	$	32,538	$	17,724,731		$	(25,705,993	)	$	(7,947,382	)
Series A Convertible Preferred Stock dividends:
Accrual of earned dividends		-		-		-		-		(223,391	)		-			(223,391	)
Payment of dividends in kind
Payment of dividends in kind, shares
Issuance of common stock pursuant to cashless warrant exercise		-		-		125,071		125		(125	)		-			-
Issuance of warrants in connection with issuance of convertible notes payable		-		-		-		-		196,966			-			196,966
Issuance of warrants in connection with exchange of convertible notes payable		-		-		-		-		139,728			-			139,728
Warrants issued in satisfaction of accrued interest		-		-		-		-		82,350			-			82,350
Stock-based compensation:
Options		-		-		-		-		206,400			-			206,400
Warrants		-		-		-		-		31,276			-			31,276
Common stock
Common stock, shares
Issuance of Series A Convertible Preferred Stock for cash
Issuance of Series A Convertible Preferred Stock for cash, shares
Issuance of common stock in connection with extension of notes payable
Issuance of common stock in connection with extension of notes payable
Reclassification of derivative liabilities to equity
Issuance of warrants in connection with issuance of notes payable
Issuance of warrants in connection with issuance of advance payable
Net loss		-		-		-		-		-			(1,524,741	)		(1,524,741	)
Balance, March 31, 2021		1,342,195		1,342		32,663,482		32,663		18,157,935			(27,230,734	)		(9,038,794	)
Series A Convertible Preferred Stock dividends:
Accrual of earned dividends		-		-		-		-		(225,873	)		-			(225,873	)
Payment of dividends in kind		-		-		632,677		633		473,842			-			474,475
Issuance of warrants in connection with issuance of convertible notes payable		-		-		-		-		37,512			-			37,512
Stock-based compensation:
Common stock		-		-		5,405		5		2,535			-			2,540
Warrants		-		-		-		-		36,343			-			36,343
Net loss		-		-		-		-		-			(1,313,113	)		(1,313,113	)
Balance, June 30, 2021		1,342,195	$	1,342		33,301,564	$	33,301	$	18,482,294		$	(28,543,847	)	$	(10,026,910	)


	FOR THE THREE MONTHS ENDED MARCH 31, 2022
	Convertible Preferred				Convertible Preferred								Additional						Total
	Stock - Series A				Stock - Series C				Common Stock				Paid-In			Accumulated			Stockholders’
	Shares		Amount		Shares		Amount		Shares		Amount		Capital			Deficit			Deficiency

Balance, January 1, 2022		1,342,195	$	1,342		272,021	$	272		34,360,546	$	34,361	$	21,316,318		$	(31,178,428	)	$	(9,826,135	)

Conversion of convertible notes payable and accrued interest into Series C Convertible Preferred Stock and common stock		-		-		183,422		183		76,530		76		1,432,836			-			1,433,095

Series A and C Convertible Preferred Stock dividends: Accrual of earned dividends		-		-		-		-		-		-		(324,917	)		-			(324,917	)

Issuance of warrants in connection with issuance of convertible notes payable		-		-		-		-		-		-		8,043			-			8,043

Stock-based compensation: Warrants		-		-		-		-		-		-		5,372			-			5,372

Net loss		-		-		-		-		-		-		-			(1,292,575	)		(1,292,575	)

Balance, March 31, 2022		1,342,195	$	1,342		455,443	$	455		34,437,076	$	34,437	$	22,437,652		$	(32,471,003	)	$	(9,997,117	)

	FOR THE SIX MONTHS ENDED JUNE 30, 2020
	Convertible Preferred								Additional						Total
	Stock - Series A				Common Stock				Paid-In			Accumulated			Stockholders’
	Shares		Amount		Shares		Amount		Capital			Deficit			Deficiency

Balance, January 1, 2020		1,245,083	$	1,245		27,076,762	$	27,077	$	15,375,565		$	(21,145,828	)	$	(5,741,941	)
Issuance of Series A Convertible Preferred Stock for cash		13,333		13		-		-		99,987			-			100,000
Series A Convertible Preferred Stock dividends:
Accrual of earned dividends		-		-		-		-		(211,305	)		-			(211,305	)
Issuance of common stock in connection with extension of notes payable		-		-		227,500		227		56,648			-			56,875
Reclassification of derivative liabilities to equity		-		-		-		-		345,830			-			345,830
Stock-based compensation:
Common stock		-		-		25,671		26		6,392			-			6,418
Net loss		-		-		-		-		-			(813,747	)		(813,747	)
Balance, March 31, 2020		1,258,416		1,258		27,329,933		27,330		15,673,117			(21,959,575	)		(6,257,870	)
Balance		1,258,416		1,258		27,329,933		27,330		15,673,117			(21,959,575	)		(6,257,870	)
Issuance of Series A Convertible Preferred Stock for cash		3,333		3		-		-		24,997			-			25,000
Issuance of common stock in connection with extension of notes payable		-		-		525,000		525		130,725			-			131,250
Issuance of warrants in connection with issuance of notes payable		-		-		-		-		161,256			-			161,256
Issuance of warrants in connection with issuance of advance payable		-		-		-		-		24,386			-			24,386
Series A Convertible Preferred Stock dividends:
Accrual of earned dividends		-		-		-		-		(211,885	)					(211,885	)
Payment of dividends in kind		-		-		574,576		574		430,331						430,905
Stock-based compensation:
Common stock		-		-		1,270,000		1,270		316,230			-			317,500
Warrants		-		-		-		-		16,129			-			16,129
Net loss		-		-		-		-		-			(1,164,688	)		(1,164,688	)
Balance, June 30, 2020		1,261,749	$	1,261		29,699,509	$	29,699	$	16,565,286		$	(23,124,263	)	$	(6,528,017	)
Balance		1,261,749	$	1,261		29,699,509	$	29,699	$	16,565,286		$	(23,124,263	)	$	(6,528,017	)


[2]	Excludes shares of common stock underlying convertible notes that are expected to become convertible into shares of Series B ~~and Series C~~ Convertible Preferred Stock since such stock had not been designated by the Company as of ~~June 30,~~March 31, 2022 and 2021. ~~See Note 9,~~ ~~Subsequent Events~~ ~~for additional details.~~

	Accrued			Accrued
	Interest			Compensation			Total

Balance - January 1, 2021	$	539,836		$	84,953		$	624,789

Change in fair value		41,607			97			41,704
Issuance of warrants		(82,350	)		-			(82,350	)

Balance - March 31, 2021		499,093			85,050			584,143
Balance, beginning		499,093			85,050			584,143

Change in fair value		37,994			(9	)		37,985
Accrual of warrant obligation		164,857			-			164,857
Accrual of common stock obligation		-			7,097			7,097

Balance - June 30, 2021	$	701,944		$	92,138		$	794,082
Balance, ending	$	701,944		$	92,138		$	794,082

	●	Organ failure and transplantation. A variety of conditions can be treated by the transplantation of vital organs. However, transplantation is limited both by the insufficient supply of available donor organs and the need for lifelong, daily ~~anti-reject~~anti-rejection treatments post-transplant. Haploidentical organ transplants, with sustained chimerism, have the potential to make life saving transplants accessible to the majority of patients, with the prospect of improved life quality and expectancy.

	●	Non-malignant hematological conditions (such as type one diabetes and sickle cell anemia) which could, in many cases, also be more effectively treated by stem cell transplantation if the procedure could be made safer and more accessible by inducing sustained tolerance in the stem cell transplant recipient.

	June 30, 2021			December 31, 2020

Cash	$	81,705		$	241,619
Restricted cash	$	3,500		$	3,500
Working capital deficiency	$	(10,030,410	)	$	(7,950,882	)

	●	Establishment of total enterprise or equity value;
	●	Analysis of equity rights for each class of security;
	●	Selection of appropriate model for valuation purposes;
	●	Determination of key valuation inputs; and
	●	Computation of the fair value of the subject security.

3.6*	~~Certificate of Designation of Preferences, Rights and Limitations of Series C Preferred Stock~~.

10.64*	~~Third Amended and Restated 10.0% Convertible Note~~

31*	Certification of principal executive officer and principal financial officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

32*	Certification of principal executive officer and principal financial officer pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.

101.INS	Inline XBRL Instance Document

101.SCH	Inline XBRL Taxonomy Extension Schema Document

101.CAL	Inline XBRL Taxonomy Extension Calculation Linkbase Document

101.DEF	Inline XBRL Taxonomy Extension Definition Linkbase Document

101.LAB	Inline XBRL Taxonomy Extension Label Linkbase Document

101.PRE	Inline XBRL Taxonomy Extension Presentation Linkbase Document

104	Cover Page Interactive Data File (embedded within the Inline XBRL document)

	CELL SOURCE, INC.

Dated: ~~August 12, 2021~~November 2, 2022	By:	/s/ Itamar Shimrat
	Name:	Itamar Shimrat
	Title:	Chief Executive Officer and Chief Financial Officer (Principal Executive, Financial and Accounting Officer)