UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 10-Q


	☒	QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended March 31, ~~2021~~2022



	☐	TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from ___ to ___

Commission File Number 001-36305

SEMLER SCIENTIFIC, INC.

(Exact name of registrant as specified in its charter)

Delaware	26-1367393
(State or other jurisdiction of	(I.R.S. Employer
incorporation or organization)	Identification No.)

2340-2348 Walsh Avenue, Suite 2344

Santa Clara, CA 95051

(Address of principal executive offices) (Zip Code)

(877) 774-4211

(Registrant’s telephone number, including area code)

Securities registered pursuant to Section 12(b) of the Act: None.

Title of each class		Trading Symbol(s)		Name of each exchange on which registered
~~N/A~~Common Stock, par value $0.001 per share		~~N/A~~SMLR		~~N/A~~The Nasdaq Stock Market LLC

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ☒ No ☐

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes ☒ No ☐

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act:

Large Accelerated Filer	☐	Accelerated Filer	☐

Non-Accelerated Filer	☒	Smaller Reporting Company	☒

Emerging growth company	☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐ No ☒

As of ~~May 3, 2021,~~April 29, 2022, there were ~~6,725,226~~6,792,753 shares of the issuer’s common stock, $0.001 par value per share, outstanding.

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TABLE OF CONTENTS

In this report, unless otherwise stated or as the context otherwise requires, references to “Semler Scientific,” “the Company,” “we,” “us,” “our” and similar references refer to Semler Scientific, Inc. The Semler Scientific logo, QuantaFlo and other trademarks or service marks of Semler Scientific, Inc. appearing in this report are the property of Semler Scientific, Inc. This report also contains registered marks, trademarks and trade names of other companies. All other trademarks, registered marks and trade names appearing in this report are the property of their respective holders.

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CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS

This quarterly report on Form 10-Q contains forward-looking statements. Such forward-looking statements include those that express plans, anticipation, intent, contingency, goals, targets or future development and/or otherwise are not statements of historical fact. In some cases, you can identify forward-looking statements by terminology, such as “expects,” “anticipates,” “intends,” “estimates,” “plans,” “believes,” “seeks,” “may,” “should,” “continue,” “could” or the negative of such terms or other similar expressions. Any forward-looking statements are qualified in their entirety by reference to the factors discussed throughout this report. These forward-looking statements are based on our current expectations and projections about future events and they are subject to risks and uncertainties known and unknown that could cause actual results and developments to differ materially from those expressed or implied in such ~~statements.~~

~~In some cases, you can identify forward-looking~~ statements, by terminology, such as “expects,” “anticipates,” “intends,” “estimates,” “plans,” “believes,” “seeks,” “may,” “should,” “continue,” “could” or the negative of such terms or other similar expressions. Accordingly, these statements involve estimates, assumptions and uncertainties that could cause actual results to differ materially from those expressed in them. Any forward-looking statements are qualified in their entirety by reference to the factors discussed throughout this report.including risks associated with:

●

implementation of our business strategy and the fact that we actively market only two FDA-cleared products and may not benefit from our recent investments in other companies developing complementary products or the extension of QuantaFlo to test for other diseases;

●

the failure of physicians and other customers to widely adopt our products, or to determine that our product provides a safe and effective alternative to existing ankle brachial index, or ABI, devices;

●

the fact that our testing product is generally but not specifically approved for reimbursement under any third-party payor codes;

●

our reliance on the talents of a small number of key personnel, and a small direct sales force;

●

not requiring customers to enter into long-term licenses;

●

concentration of our revenues and accounts receivable with a limited number of customers;

●

our reliance on a small number of independent suppliers and facilities for the manufacturing of our product;

●

our business being subject to many laws and government regulations, including governing the manufacture and sale of medical devices, patient data, and others;

●

our ability to protect our intellectual property;

●

impacts of the ongoing Covid-19 pandemic and macroeconomic factors that could impact our business, such as the effects of the Russian invasion of Ukraine on the global economy and supply chain; and

●

the other factors set forth under the caption “Risk Factors” in our annual report on Form 10-K filed with the Securities and Exchange Commission, or SEC, on March 4, 2022.

You should read this quarterly report and the documents that we reference herein and therein and have filed as exhibits to this report and our other filings with the Securities and Exchange Commission, or SEC, completely and with the understanding that our actual future results may be materially different from what we expect. You should assume that the information appearing in this quarterly report is accurate as of the date of this quarterly report only. Because the risks and uncertainties referred to above and in our SEC reports could cause actual results or outcomes to differ materially from those expressed in any forward-looking statements made by us or on our behalf, you should not place undue reliance on any forward-looking statements. ~~These risks~~

You should read this quarterly report and ~~uncertainties, along with others, are described under~~ the ~~heading “Risk Factors” in~~documents that we reference herein and therein and have filed as exhibits to this report and our ~~annual report on Form 10-K filed~~other filings with the ~~SEC on March 9, 2021.~~SEC. You should assume that the information appearing in this quarterly report is accurate as of the date of this quarterly report only. Further, any forward-looking statement speaks only as of the date on which it is made, and we undertake no obligation to update any forward-looking statement to reflect events or circumstances after the date on which the statement is made or to reflect the occurrence of unanticipated events. New factors emerge from time to time, and it is not possible for us to predict which factors will arise. In addition, we cannot assess the impact of each factor on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements. We qualify all of the information presented in this quarterly report, and particularly our forward-looking statements, by these cautionary statements.

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PART I—FINANCIAL INFORMATION

Item 1. Financial Statements.

Semler Scientific, Inc.

Condensed Statements of Income

Unaudited

(In thousands of U.S. Dollars, except share and per share data)

For the three months ended March 31,

2021

2020

Revenues

$
13,183

$
9,430

Operating expenses:

Cost of revenues

1,579

850

Engineering and product development

693

842

Sales and marketing

2,816

2,695

General and administrative

2,076

1,591

Total operating expenses

7,164

5,978

Income from operations

6,019

3,452

Interest income

3

2

Other expense

(2)

(4)

Other income (expense)

1

(2)

Pre-tax net income

$
6,020

$
3,450

Income tax provision

1,143

777

Net income

4,877

2,673

Net income per share, basic

$
0.73

$
0.41

Weighted average number of shares used in computing basic income per share

6,710,990

6,533,369

Net income per share, diluted

$
0.60

$
0.33

Weighted average number of shares used in computing diluted income per share

8,169,375

8,065,813


	For the three months ended March 31,
		2022		2021

Revenues	$	14,016	$	13,183
Operating expenses:
Cost of revenues		970		1,579
Engineering and product development		1,126		693
Sales and marketing		4,676		2,816
General and administrative		3,302		2,076
Total operating expenses		10,074		7,164
Income from operations		3,942		6,019
Interest income		1		3
Other expenses		—		(2)
Other income		1		1
Pre-tax net income		3,943		6,020
Income tax provision		583		1,143
Net income	$	3,360	$	4,877
Net income per share, basic	$	0.50	$	0.73
Weighted average number of shares used in computing basic income per share		6,777,950		6,710,990
Net income per share, diluted	$	0.41	$	0.60
Weighted average number of shares used in computing diluted income per share		8,116,456		8,169,375

See accompanying notes to unaudited condensed financial statements.

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Semler Scientific, Inc.

Condensed Balance Sheets

(In thousands of U.S. Dollars, except share and per share data)


	March 31,		December 31,		March 31,		December 31,
	2021		2020		2022		2021
		Unaudited				Unaudited
Assets
Current Assets:
Cash	$	26,478	$	22,079
Trade accounts receivable, net of allowance for doubtful accounts of $61 and $61, respectively		4,399		2,808
Cash and cash equivalents					$	38,426	$	37,323
Trade accounts receivable, net of allowance for doubtful accounts of $71 and $61, respectively						5,416		3,619
Inventory		639		340		595		550
Prepaid expenses and other current assets		1,769		1,376		6,033		4,044
Total current assets		33,285		26,603		50,470		45,536
Assets for lease, net		1,828		1,941		1,594		1,643
Property and equipment, net		351		261		470		394
Other non-current assets		392		418		313		332
Long-term investments		3,051		3,051		821		821
Long-term deferred tax assets		1,739		2,365		1,767		1,946
Total assets	$	40,646	$	34,639	$	55,435	$	50,672

Liabilities and Stockholders’ Equity
Current liabilities:
Accounts payable	$	470	$	677	$	375	$	443
Accrued expenses		3,477		2,798		4,383		3,436
Deferred revenue		1,049		963		980		921
Other short-term liabilities		77		76		81		80
Total current liabilities		5,073		4,514		5,819		4,880

Long-term liabilities:
Other long-term liabilities		305		332		224		245
Total long-term liabilities		305		332		224		245
Commitments and contingencies (Note 10)
Stockholders’ equity:
Common stock, $0.001 par value; 50,000,000 shares authorized; 6,745,806, and 6,725,422 shares issued, and 6,720,806 and 6,700,422 shares outstanding (treasury shares of 25,000 and 25,000, respectively)		7		7
Common stock, $0.001 par value; 50,000,000 shares authorized; 6,855,168, and 6,824,380 shares issued, and 6,787,216 and 6,758,458 shares outstanding (treasury shares of 67,952 and 65,922, respectively)						7		7
Additional paid-in capital		22,711		22,113		21,130		20,645
Retained earnings		12,550		7,673		28,255		24,895

Total stockholders’ equity		35,268		29,793		49,392		45,547

Total liabilities and stockholders’ equity	$	40,646	$	34,639	$	55,435	$	50,672

See accompanying notes to unaudited condensed financial statements.

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Semler Scientific, Inc.

Statements of Stockholders’ Equity

Unaudited

(In thousands of U.S. Dollars, except share and per share data)

For the Three Months Ended March 31, 2020

Common Stock

Treasury Stock

Additional

Common Stock

Paid-In

Accumulated Deficit

Total Stockholders'


Shares Issued

Amount

Shares

Amount

Capital



Equity
Balance at December 31, 2019

6,556,221

$
7

(25,000)

$
—

$
19,400

$
(6,334)

$
13,073
Stock Option Exercises

2,855

—

—

—

3

—

3
Stock-based Compensation

—

—

—

—

67

—

67
Net income

—

—

—

—

—

2,673

2,673
Balance at March 31, 2020

6,559,076

$
7

(25,000)

$
—

$
19,470

$
(3,661)

$
15,816


	For the Three Months Ended March 31, 2021												For the Three Months Ended March 31, 2021
	Common Stock			Treasury Stock			Additional						Common Stock			Treasury Stock			Additional
		Common Stock					Paid-In		Retained Earnings		Total Stockholders'			Common Stock					Paid-In		Retained Earnings		Total Stockholders'
	Shares Issued	Amount		Shares	Amount		Capital				Equity		Shares Issued	Amount		Shares	Amount		Capital				Equity
Balance at December 31, 2020	6,725,422	$	7	(25,000)	$	—	$	22,113	$	7,673	$	29,793	6,725,422	$	7	(25,000)	$	—	$	22,113	$	7,673	$	29,793
Employee Stock Grant	5,400		—	—		—		537		—		537
Stock Option Exercises	14,984		—	—		—		9		—		9
Stock-based Compensation	—		—	—		—		52		—		52
Employee stock grants													5,400		—	—		—		537		—		537
Stock option exercises													14,984		—	—		—		9		—		9
Stock-based compensation													—		—	—		—		52		—		52
Net income	—		—	—		—		—		4,877		4,877	—		—	—		—		—		4,877		4,877
Balance at March 31, 2021	6,745,806	$	7	(25,000)	$	—	$	22,711	$	12,550	$	35,268	6,745,806	$	7	(25,000)	$	—	$	22,711	$	12,550	$	35,268


	For the Three Months Ended March 31, 2022
	Common Stock			Treasury Stock			Additional
		Common Stock					Paid-In		Retained Earnings		Total Stockholders'
	Shares Issued	Amount		Shares	Amount		Capital				Equity
Balance at December 31, 2021	6,824,380	$	7	(65,922)	$	—	$	20,645	$	24,895	$	45,547
Treasury stock acquired	—		—	(2,030)		—		(99)		—		(99)
Employee stock grant	8,406		—	—		—		628		—		628
Taxes paid related to net share settlement of equity awards	(1,418)		—	—		—		(106)		—		(106)
Stock option exercises	23,800		—	—		—		62		—		62
Net income	—		—	—		—		—		3,360		3,360
Balance at March 31, 2022	6,855,168	$	7	(67,952)	$	—	$	21,130	$	28,255	$	49,392

See accompanying notes to unaudited condensed financial statements

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Semler Scientific, Inc.

Condensed Statements of Cash Flows

Unaudited

(In thousands of U.S. Dollars)

For the three months ended March 31


2021

2020

CASH FLOWS FROM OPERATING ACTIVITIES:

Net income

$
4,877

$
2,673

Reconciliation of Net Income to Net Cash Provided by Operating Activities:





Depreciation

155

159

Deferred tax expense

626

721

Loss on disposal of assets for lease

83

66

Allowance for doubtful accounts

5

31

Stock-based compensation expense

589

67

Changes in Operating Assets and Liabilities:

Trade accounts receivable

(1,595)

1,875

Inventory

(299)

(39)

Prepaid expenses and other current assets

(393)

(457)

Other non-current assets

26

—

Accounts payable

(207)

39

Accrued expenses

679

(1,466)

Other current and non-current liabilities

(26)

—

Deferred revenue

86

34

Net Cash Provided by Operating Activities

4,606

3,703

CASH FLOWS FROM INVESTING ACTIVITIES:

Additions to property and equipment

(133)

(91)

Purchase of assets for lease

(83)

(142)

Net Cash Used in Investing Activities

(216)

(233)

CASH FLOWS FROM FINANCING ACTIVITIES:





Exercise of stock options

9

3

Net Cash Provided by Financing Activities

9

3

INCREASE IN CASH

4,399

3,473

CASH, BEGINNING OF PERIOD

22,079

7,741

CASH, END OF PERIOD

$
26,478

$
11,214


	For the three months ended March 31
	2022		2021
CASH FLOWS FROM OPERATING ACTIVITIES:
Net income	$	3,360	$	4,877

Reconciliation of Net Income to Net Cash Provided by Operating Activities:
Depreciation		155		155
Deferred tax expense		179		626
Loss on disposal of assets for lease		74		83
Allowance for doubtful accounts		21		5
Stock-based compensation expense		628		589
Changes in Operating Assets and Liabilities:
Trade accounts receivable		(1,818)		(1,595)
Inventory		(45)		(299)
Prepaid expenses and other current assets		(1,988)		(393)
Other non-current assets		19		26
Accounts payable		(68)		(207)
Accrued expenses		946		679
Other current and non-current liabilities		(20)		(26)
Deferred revenue		59		86
Net Cash Provided by Operating Activities		1,502		4,606

CASH FLOWS FROM INVESTING ACTIVITIES:
Additions to property and equipment		(122)		(133)
Purchase of assets for lease		(134)		(83)
Net Cash Used in Investing Activities		(256)		(216)

CASH FLOWS FROM FINANCING ACTIVITIES:
Taxes paid related to net settlement of equity awards		(106)		-
Treasury stock acquired		(99)		-
Proceeds from exercise of stock options		62		9
Net Cash (Used in) Provided by Financing Activities		(143)		9
INCREASE IN CASH		1,103		4,399
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD		37,323		22,079
CASH AND CASH EQUIVALENTS, END OF PERIOD	$	38,426	$	26,478

See accompanying notes to unaudited condensed financial statements

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Semler Scientific, Inc.

Notes to Condensed Financial Statements

Unaudited

(In thousands of U.S. Dollars, except share and per share data)

1. Basis of Presentation

Semler Scientific, Inc., a Delaware corporation (“Semler” or “the Company”), prepared the unaudited interim financial statements included in this report in accordance with United States generally accepted accounting principles (“GAAP”) and applicable rules and regulations of the Securities and Exchange Commission (“SEC”) for interim financial reporting. Certain information and note disclosures normally included in the financial statements prepared in accordance with GAAP have been condensed or omitted pursuant to such rules and regulations. As such, the information included in this quarterly report on Form 10-Q should be read in conjunction with the audited financial statements and notes thereto included in the Company’s annual report on Form 10-K for the year ended December 31, ~~2020~~2021 filed with the SEC on March ~~9, 2021~~4, 2022 (the “Annual Report”). In the opinion of management, these financial statements include all adjustments (consisting of normal recurring adjustments) necessary for a fair statement of the financial position, results of operations and cash flows for the periods presented. The results of operations for the interim periods shown in this report are not necessarily indicative of the results that may be expected for any future period, including the full year.

~~Reclassification of Prior Year Presentation~~

~~Certain prior year amounts have been reclassified for consistency with the current period presentation. These reclassifications had no effect on the reported results of operations.~~

COVID-19

~~On January 30, 2020, the World Health Organization (“WHO”) declared the recent novel coronavirus (COVID-19) outbreak a global health emergency,~~In 2021, variable fee license revenues (fee-per-test), which ~~prompted national, state and local governments to begin putting actions~~grew strongly in place to slow the spread of COVID-19. In March 2020, the WHO classified the COVID-19 outbreak as a pandemic. The outbreak of COVID-19 resulted in travel restrictions, quarantines, “stay-at-home” and “shelter-in-place” orders and extended shutdown of certain businesses around the world. While restrictions began to ease in the second quarter and activities began to resume, recent outbreaks could lead to restrictions being reimplemented. In the first half of ~~2020, the Company’s revenues, primarily from variable-fee licenses, were negatively impacted by the COVID-19 pandemic. In~~2021, decreased subsequently in the second half of ~~2020 and~~2021. The Company believes this new pattern in the home-testing market is due to a COVID-19 related timing change in the behavior of insurance plans when ordering QuantaFlo testing from its health risk assessment customers.

The first quarter results of ~~2021,~~2022 support this pattern of testing earlier in the ~~Company’s~~year, as the home-testing market had higher volume of sequential revenues, ~~primarily from variable-fee licenses, rebounded~~which grew 67% compared to the fourth quarter of 2021. However, the Company does not know if this newly observed pattern will continue in 2022 or in future years.

The Company believes that the relatively slower growth in the period-over-period comparison, was due to the COVID-19 pandemic. The Company's staff and ~~even exceeded pre-COVID-19 levels.~~ many of its customers and prospects experienced a higher-than-normal rate of employee absence due to illness, which can have a slowing effect on its sales cycle.

The extent and duration of the pandemic is unknown, and the future effects on the Company’s business are uncertain and difficult to predict. The Company is continuing to monitor the events and circumstances surrounding the COVID-19 pandemic, which may require adjustments to the Company’s estimates and assumptions in the future.

Recently Issued Accounting Pronouncements

Accounting Pronouncements Recently Adopted

In ~~December 2019,~~May 2021, the ~~Financial~~financial Accounting Standards ~~Board (“~~Board(“FASB”) issued Accounting Standards Update (“ASU”) No. ~~2019-12,~~ ~~Income Taxes~~2021-04, Earnings Per Share (Topic ~~740): Simplifying the~~260), Debt—Modifications and Extinguishments (Subtopic 470-50), Compensation—Stock Compensation (Topic 718), and Derivatives and Hedging—Contracts in Entity’s Own Equity (Subtopic 815-40) Issuer’s Accounting for ~~Income Taxes~~Certain Modifications or Exchanges of Freestanding Equity-Classified Written Call Options~~, which simplifies~~. This update provides guidance for a modification or an exchange of a freestanding equity-classified written call option that is not within the ~~accounting for income taxes by removing certain exceptions to the general principles for income taxes.~~scope of another Topic. This update is effective for the Company’s ~~annual periods~~fiscal years beginning after December 15, ~~2020, including interim periods within those fiscal years.~~2021. The Company adopted ~~the new standard on~~this ASU prospectively effective January 1, ~~2021~~2022 and determined that the adoption of this new accounting ~~guidance~~standard did not have a material impact on its financial statements.

In ~~January 2020,~~July 2021, the FASB issued ASU No. ~~2020-01,~~ 2021-05, ~~Investments-Equity Securities~~Leases (Topic ~~321), Investments-Equity Method~~842): Lessors—Certain Leases with Variable Lease Payments. This update addresses stakeholders’ concerns by amending the lease classification requirements for lessors to align them with practice under Topic 840. Lessors should classify and ~~Joint Ventures (Topic 323), and Derivatives and Hedging (Topic 815).~~ ~~The amendments in this ASU clarify the interaction between the accounting~~account for ~~investments in equity securities, investment in equity method and certain derivatives instruments. The ASU is expected to reduce diversity in practice and increase comparability~~a lease with variable lease payments that do not depend on a reference index or a rate as an operating lease if both of the ~~accounting for these interactions.~~following criteria are met: i) The lease would have been classified as a sales-type lease or a direct financing lease in accordance with the classification criteria in paragraphs 842-10-25-2 through 25-3, ii) the lessor would have otherwise recognized a day-one loss. This ~~ASU~~update is effective for the Company’s fiscal years beginning after ~~December 15, 2020. The Company adopted the new standard on January 1, 2021 and determined that the adoption of this new accounting guidance did not have an impact on its financial statements.~~

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Semler Scientific, Inc.

Notes to Condensed Financial Statements

Unaudited

(In thousands of U.S. Dollars, except share and per share data)

~~In October 2020, the FASB issued ASU No. 2020-10,~~ ~~Codification Improvements~~. This ASU is the final update of the 2019 proposed ASU, Codification Improvements, of which various topics in the Codification are amended, clarified, simplified, or otherwise modified to improve the Codification. The amendments in Section B of this ASU improve the Codification by ensuring that all guidance that requires or provides an option for an entity to provide information in the notes to financial statements is codified in the disclosure section of the Codification. The amendments in Section C of this ASU are varied in nature and may affect the application of the guidance in cases which the original guidance may have been unclear. The amendments in Sections B and C of this ASU are effective for the Company’s annual periods beginning after December 15, ~~2020, and the amendments should be applied retrospectively, and should be applied at the beginning of the period that includes the adoption date.~~ 2021. The Company adopted this ASU prospectively to the ~~new standard~~leases that commence or modified on or after January 1, ~~2021~~2022 and determined that the adoption of this new accounting ~~guidance~~standard did not have a material impact on its financial statements.

In November 2021, the FASB issued ASU No. 2021-10, Government Assistance (Topic 832): Disclosures by Business Entitiesabout Government Assistance. This ASU increases the transparency of government assistance to include the disclosure of (1) the types of assistance, (2) an entity's accounting for the assistance, and (3) the effect of the assistance on an entity's financial statements. The guidance in ASU 2021-10 is effective for financial statements of all entities, including private companies, for annual periods beginning after December 15, 2021, with early application permitted. Entities are required to provide the new disclosures prospectively for all transactions with a government entity that are accounted for under either a grant or a contribution accounting model and are reflected in the financial statements at the date of initially applying the new amendments, and to new transactions entered into after that date. The Company adopted ASU No. 2021-10 prospectively to the government assistance received after January 1, 2022 and determined that the adoption of this new accounting standard did not have a material impact on its financial statements.

Accounting Pronouncements Not Yet Adopted

In June 2016, the FASB issued ASU No. 2016-13, Financial Instruments – Credit Losses (Topic 326): Measurement of Credit Losses on Financial Instruments (“Topic 326”). This ASU requires timelier recording of credit losses on loans and other financial instruments held. Instead of reserves based on a current probability analysis, Topic 326 requires the measurement of all expected credit losses for financial assets held at the reporting date based on historical experience, current conditions, and reasonable and supportable forecasts. All organizations will now use forward-looking information to better inform their credit loss estimates. Topic 326 requires enhanced disclosures regarding significant estimates and judgments used in estimating credit losses, as well as the credit quality and underwriting standards of an organization’s portfolio. These disclosures include qualitative and quantitative requirements that provide information about the amounts recorded in the financial statements. In addition, Topic 326 amends the accounting for credit losses on available-for-sale debt securities and purchased financial assets with credit deterioration. In April 2019, the FASB issued ASU No. 2019-04, Codification Improvements to Topic 326 Financial Instruments—Credit Losses, Topic 815, Derivatives and Hedging, and Topic 825, Financial Instruments, to introduce amendments which will affect the recognition and measurement of financial instruments, including derivatives and hedging. In May 2019, the FASB issued ASU No. 2019-05, Financial Instruments – Credit Losses (Topic 326); Targeted Transition Relief. The amendments in this ASU provide entities that have certain instruments within the scope of Subtopic 326-20 with an option to irrevocably elect the fair value option in Subtopic 825-10, applied on an instrument-by-instrument basis for eligible instruments upon adoption of Topic 326. This standard and related amendments are effective for the Company’s fiscal years beginning after December 15, 2022, including interim periods within those fiscal years. The Company will adopt the new standard in the first quarter of fiscal year 2023. The Company is evaluating the effect of adopting this new accounting guidance but does not ~~anticipate this new standard~~expect adoption will have a material impact on ~~its~~the Company's financial statements.

In March 2020, ~~the~~ FASB issued ASU No. 2020-03, Codification Improvements to Financial Instruments. This ASU improves and clarifies various financial instruments topics, including the current expected credit losses standard issued in 2016 (ASU No. 2016-13). The ASU includes seven different issues that describe the areas of improvement and the related amendments to GAAP, intended to make the standards easier to understand and apply by eliminating inconsistencies and providing clarifications. The amendments have different effective dates. The issues 1-5 are conforming amendments, which are effective upon issuance of this final update. The Company determined that issues 1-5 have no impact on its financials. The amendments related to issue 6 and 7 effect ASU No. 2016-13, Financial instruments – credit losses (Topic 326): measurement of credit losses on financial statements. Effective dates of issue 6 and 7 are the same as the effective date of ASU No. 2016-13. The Company will adopt the new standard in the first quarter of fiscal year 2023.The Company is evaluating the effect of adopting this new accounting guidance, but does not expect adoption will have a material impact on the Company's financial statements.

In ~~March 2020,~~October 2021, the FASB issued ASU ~~No. 2020-04,~~No.2021-08, ~~Reference Rate Reform~~Business Combinations (Topic ~~848)~~805): ~~Facilitation of the Effects of Reference Rate Reform on Financial Reporting~~ Accounting for Contract Assets and Contract Liabilities from Contracts with Customers. This ASU ~~provides optional expedient~~improves the accounting for acquired revenue contracts with customers in a business combination by addressing diversity in practice and ~~exceptions for applying generally accepted accounting principles~~inconsistency related to ~~contracts, hedging relationships,~~recognition of an acquired contract liability and ~~other transactions affected~~payment terms and their effect on subsequent revenue recognized by ~~reference rate reform if certain criteria are met. In response to~~ the concerns about structural risks of interbank offered rates and, particularly, the risk of cessation of the London Interbank Offered Rate, regulators in several jurisdictions around the world have undertaken reference rate reform initiatives to identify alternative reference rates that are more observable or transaction-based and less susceptible to manipulation. The ASU provides companies with optional guidance to ease the potential accounting burden associated with transitioning away from reference rates that are expected to be discontinued. The ASU can be adopted no later than December 1, 2022, with early adoption permitted. The Company has not yet adopted this ASU and is evaluating the effect of adopting this new accounting guidance.

~~In August 2020, the FASB issued ASU No. 2020-06,~~ ~~Debt--Debt with Conversion and Other Options (Subtopic 470-20)~~ ~~and Derivatives and Hedging— Contracts in Entity's Own Equity (Subtopic 815-40)~~acquirer. ~~The amendments in this ASU affect~~For public business entities, ~~that issue convertible instruments and/or contracts in an entity's own equity. For contracts in an entity's own equity, the contracts primarily affected~~

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Notes to Condensed Financial Statements

Unaudited

(In thousands of U.S. Dollars, except share and per share data)

~~are freestanding instruments and embedded features that are accounted for as derivatives under the current~~this guidance because of failure to meet the settlement conditions of the derivatives scope exception related to certain requirements of the settlement assessment. The FASB simplified the settlement assessment by removing the requirements (1) to consider whether the contract would be settled in registered shares, (2) to consider whether collateral is required to be posted, and (3) to assess shareholder rights. Those amendments also affect the assessment of whether an embedded conversion feature in a convertible instrument qualifies for the derivatives scope exception. Additionally, the amendments in this ASU affect the diluted EPS calculation for instruments that may be settled in cash or shares and for convertible instruments. The ASU reduces the number of accounting models for convertible debt instruments and convertible preferred stock by eliminating the beneficial conversion feature model and cash conversion model. As compared with current GAAP, more convertible debt instruments will be reported as a single liability instrument and more convertible preferred stock as a single equity instrument. The interest rate of more convertible debt instruments will be closer to the coupon interest rate. This ASU is effective for ~~the Company’s~~ fiscal years beginning after December 15, ~~2021, including~~2022 and for interim periods within those fiscal years. ~~Early adoption~~For all other entities, this guidance is ~~permitted, but no earlier than~~effective for fiscal years beginning after December 15, ~~2020, including~~2023 and for interim periods within those fiscal years. This ASU should be applied prospectively to all business combinations in the year of adoption. The Company ~~has not yet adopted this ASU and is evaluating~~will adopt the ~~effect~~new standard in the first quarter of ~~adopting this new accounting guidance.~~

~~In January 2021, the FASB issued ASU No. 2021-01,~~ ~~Reference Rate Reform (Topic 848)~~. This ASU clarifies the scope of Topic 848 so that derivatives affected by the discounting transition due to reference rate reform initiatives are explicitly eligible for certain optional expedients and exceptions in Topic 84. In addition, to efficiently address another emerging issue related reference rate reform and respond to stakeholder feedback on the proposed feedback on the proposed update on this project, the Board decided to clarify that a receive-variable-rate, pay-variable-rate cross-currency interest rate swap may be considered an eligible hedging instrument in a net investment hedge if both legs of the swap do not have the same repricing intervals and dates as of the result of reference rate reform. The amendments in this update are elective and apply to all entities that have derivative instruments that use an interest rate for margining, discounting, or contract price alignment that is modified as a result of reference rate reform. The amendments also optionally apply to all entities that designate receive-variable-rate, pay-variable-rate cross-currency interest rate swaps as hedging instruments in net investment hedges that are modified as a result of reference rate reform. An entity may elect to apply the amendments in this update on a full retrospective basis as of any date from the beginning of an interim period that includes or is subsequent to March 12, 2020, or on a prospective basis to new modifications from any date within an interim period that includes or is subsequent to the date of the issuance of a final update, up to the date that financial statements are available to be issued. The amendments in this update do not apply to contract modifications made after December 31, 2022, new hedging relationships entered into after December 31, 2022, and existing hedging relationships evaluated for effectiveness in periods after December 31, 2022, except for hedging relationships existing as of December 31, 2022, that apply certain optional expedients in which the accounting effects are recorded through the end of the hedging relationship (including periods after December 31, 2022).fiscal year 2023. The Company ~~has~~does not ~~yet adopted~~expect the adoption of this ~~ASU and is evaluating the effect of adopting this new accounting guidance.~~standard will have a material impact on its financial statements.

2.Variably-Priced Revenue

The Company recognizes variable-fee licenses (i.e., fee per test) and sales of hardware equipment and accessories in accordance with ~~Topic~~ASC 606. Total fees from variable-fee licenses represent approximately ~~$5,658~~$5,842 and ~~$2,703~~$5,658 for the three months ended March 31, ~~2021~~2022 and ~~2020,~~2021, respectively. Total sales of hardware and equipment accessories represent approximately ~~$331~~$285 and ~~$270~~$331 of revenues for the three months ended March 31, 2022 and 2021, ~~and 2020,~~ respectively. ~~Essentially all of the variable-fee licenses are with large healthcare organizations.~~ The remainder of the revenue is earned from leasing the Company's testing product for a fixed fee, which is not subject to Topic 606.

3. Inventory

Inventory, which is made up of finished goods, is recorded at the lower of cost or net realizable value. Cost is determined on the first-in, first-out method. The Company periodically analyzes its inventory levels to identify inventory that has a cost basis in excess of its estimated realizable value, and writes down such inventory as appropriate.

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~~Notes to Condensed Financial Statements~~

~~Unaudited~~

~~(In thousands of U.S. Dollars, except share~~ Inventory balance was $595 and ~~per share data)~~

In September 2020, the Company entered into an agreement with Private company #1 to exclusively market and distribute a new product line. Product inventory under this agreement was as follows for the periods presented:

~~Under this agreement, the Company committed to purchase $1,200 of product inventory. The Company prepaid for $900 of product inventory and has received $289 of product inventory~~$550 as of March 31, ~~2021. The balance of prepaid inventory was $611 as of March 31, 2021.~~

The Company also agreed to make royalty payments ranging from 0% to 10% of net sales depending on the average net sales price of the distributed products. Unless early terminated in accordance with its terms, this exclusive distribution agreement will remain in full force and effect until December 31, 2024, and thereafter there is an option for this agreement to be automatically renewed for additional 4-year terms.

The Company had other hardware inventory of $356 purchased from other vendors as of March 31, 2021. Total inventory, which includes inventory from Private company #1, was $639 and $340 as of March 31, 20212022 and December 31, ~~2020,~~2021, respectively.

4. Assets for Lease, net

The Company enters into contracts with customers for the Company’s QuantaFlo^® product. The Company has determined these contracts meet the definition of a lease under Topic 842. Operating leases are short-term in nature (monthly, quarterly or one year), and all of which have renewal options. The assets that may be associated with these leasing arrangements are identified below as assets for lease. Upon shipment under operating leases, assets for lease are depreciated. Upon shipment under variable-fee license contracts, these assets for lease are sold to the customers, and the asset is recognized as cost of revenue under Accounting Standards Codification or ASC 606, Revenue from Contracts with Customers. During the three months ended March 31, ~~2021~~2022 and ~~2020,~~2021, the Company recognized approximately ~~$7,194~~$7,889 and ~~$6,457,~~$7,194, respectively, in lease revenues related to these ~~arrangements, which is included in Revenues on the Condensed Statements of Income.~~arrangements.

Assets for lease consist of the following:


	March 31,		December 31,		March 31,		December 31,
	2021		2020		2022		2021
Assets for lease	$	3,266	$	3,407	$	3,210	$	3,241
Less: accumulated depreciation		(1,438)		(1,466)		(1,616)		(1,598)
Assets for lease, net	$	1,828	$	1,941	$	1,594	$	1,643

Depreciation expense amounted to ~~$113~~$108 and ~~$128~~$113 for the three months ended March 31, 2022 and 2021, ~~and 2020,~~ respectively. ~~Reduction~~Reduction to accumulated depreciation for returned items was ~~$141~~$90 and ~~$65~~$141 for the three months ended March 31, 2022 and 2021, ~~and 2020,~~ respectively. The Company recognized a loss on disposal of assets for lease in the amount of ~~$83~~$74 and ~~$66~~$83 for the three months ended March 31, ~~2021~~2022 and ~~2020, respectively.~~

~~5. Property and Equipment, net~~

~~Capital assets consist of the following:~~

March 31,

December 31,

2021

2020

Capital assets

$
919

$
786

Less: accumulated depreciation

(568)

(525)

Capital assets, net

$
351

$
261

~~Depreciation expense amounted to $43 and $31 for the three months ended March 31,~~ 2021, ~~and 2020,~~ respectively.

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Notes to Condensed Financial Statements

Unaudited

(In thousands of U.S. Dollars, except share and per share data)

5. Property and Equipment, net

Capital assets consist of the following:


	March 31,		December 31,
	2022		2021
Capital assets	$	1,005	$	882
Less: accumulated depreciation		(535)		(488)
Capital assets, net	$	470	$	394

Depreciation expense amounted to $46 and $43 for the three months ended March 31, 2022 and 2021, respectively.

6.Long-Term Investments

Long term investments consist of the following for the periods presented:

March 31,

December 31,

2021

2020
Investments in Private company #2

$
2,742

$
2,742
Investments in Private company #3

309

309
Total

$
3,051

$
3,051

~~Private Company #2:~~

In October 2020, the Company purchased 211,928 shares of common stock of Private company #2 from certain sellers in exchange for 40,922 shares of the Company’s common stock. The total fair value of the purchase consideration as of December 31, 2020 was approximately $2,230. The Company had the right to, in various circumstances, sell any or all of these shares of common stock back to the sellers in exchange for the shares of the Company’s common stock originally issued to the sellers. These rights were tied to (a) Private company #2 completing a bona fide equity financing, (b) the share price in such financing, (c) the timing of delivery of certain documents to the Company or (d) at the Company’s sole option, at any time between March 31, 2021 and October 8, 2021. Subsequent to March 31, 2021, the Company exercised the put option. See Note 14 to the Unaudited Condensed Financial Statements for the details.


	March 31,		December 31,
	2022		2021
Investments in SYNAPS Dx	$	512	$	512
Investments in Mellitus Health Inc.		309		309
Total	$	821	$	821

In September 2020, the Company acquired a promissory note from ~~Private company #2~~NeuroDiagnostics Inc., which is doing business as SYNAPS Dx, in the principal amount of ~~$500, $100 of which was retained for expense reimbursement.~~$500. Subsequently, in December 2020, the Company agreed to convert the promissory note, together with all accrued interest thereon, into shares of preferred stock of ~~Private company #2~~SYNAPS Dx as repayment in full of the promissory note. The value of the note exchanged for the shares of preferred stock of ~~Private company #2~~SYNAPS Dx held by the Company as of March 31, 2022 and December 31, ~~2020~~2021 was approximately $512.

~~Private Company #3:~~

In October 2020, the Company acquired from a seller a convertible promissory note previously issued by ~~Private company #3~~Mellitus Health Inc., (“Mellitus”) to such seller for a purchase price of $59, which represented the $50 principal amount of the note and all accrued and unpaid interest thereon.

Subsequently, in October 2020, the Company purchased $250 of shares of preferred stock of ~~Private company #3,~~Mellitus, and in connection with such transaction, the convertible promissory note, together with all accrued interest thereon, also converted pursuant to its terms into shares of preferred stock of ~~Private company #3~~Mellitus as repayment in full of such convertible promissory note. The value of consideration exchanged for the shares of preferred stock of ~~Private company #3~~Mellitus held by the Company as of March 31, 2022 and December 31, 2021 was approximately $309.

~~Subsequent to March 31,~~In April 2021, the Company entered into an agreement with Mellitus to exclusively market and distribute its product line in the United States, including Puerto Rico, except for selected accounts. The Company is currently developing a marketing plan. Under this distribution agreement, ~~with Private company #3. See Note 14~~the Company agreed to ~~the Unaudited Condensed Financial Statements~~purchase $2,000 of product licenses and prepaid $2,000 for the ~~details.~~license purchases. This prepayment is included in ‘Prepaid expenses and other current assets’ in the balance sheet. Unless terminated early in accordance with its terms, the exclusive distribution agreement will remain in full force and effect until April 1, 2026, and thereafter there is an option for this agreement to be automatically renewed for additional one-year terms. Revenue from these product licenses will be recognized in accordance with ASC 606, Revenue from Contracts with Customers. Revenue from these product licenses during the three months ended March 31, 2022 was not significant.

The investments in ~~Private company #2~~SYNAPS Dx and #3Mellitus securities that were retained by the Company as of ~~December 31, 2020 and~~ March 31, ~~2021~~2022 were recorded in accordance with ASC 321, Investments – equity securities, which provides that investments in equity securities in privately-held companies without readily determinable fair values are generally recorded at cost, plus or minus subsequent observable price changes in orderly transactions for identical or similar investments, less impairments. The Company elected the practical

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Notes to Condensed Financial Statements

Unaudited

(In thousands of U.S. Dollars, except share and per share data)

expedient permitted by ASC 321 and recorded the above investments on a cost basis. As a part of the assessment for impairment indicators, the Company considers significant deterioration in the earnings performance and overall business prospects of the investee as well as significant adverse changes in the external environment these investments operate. If qualitative assessment indicates the

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~~Semler Scientific, Inc.~~

~~Notes to Condensed Financial Statements~~

~~Unaudited~~

~~(In thousands of U.S. Dollars, except share and per share data)~~

investments are impaired, the fair value of these equity securities would be estimated, which would involve a significant degree of judgement and subjectivity. ~~NaN~~In accordance with ASC 321, the Company assessed qualitatively for impairment and determined that there was ~~recorded during the three months ended~~0 impairment for these investments as of March 31, 2022 and December 31, 2021.

7. Accrued Expenses

Accrued expenses consist of the following:


	March 31,		December 31,		March 31,		December 31,
	2021		2020		2022		2021
Compensation	$	1,749	$	1,524	$	2,522	$	1,754
Accrued Taxes		1,281		861		1,339		1,159
Miscellaneous Accruals		447		413		522		523
Total Accrued Expenses	$	3,477	$	2,798	$	4,383	$	3,436

8. Concentration of Credit Risk

Credit risk is the risk of loss from amounts owed by the financial counterparties. Credit risk can occur at multiple levels; as a result of broad economic conditions, challenges within specific sectors of the economy, or from issues affecting individual companies. Financial instruments that potentially subject the Company to credit risk consist of cash and accounts receivable.

The Company maintains cash with major financial institutions. The Company’s cash ~~consists~~and cash equivalents consist of bank deposits and money market funds held with banks that, at times, exceed federally insured limits. The Company limits its credit risk by dealing with counterparties that are considered to be of high credit quality and by performing periodic evaluations of the relative credit standing of these financial institutions.

Management periodically monitors the creditworthiness of its customers and believes that it has adequately provided for any exposure to potential credit loss. For the three months ended March 31, 2022, 2 customers accounted for 35.4% and 31.7% of the Company’s revenues, respectively. For the three months ended March 31, 2021, 2 customers accounted for 38.3% and 30.4% of the Company’s ~~revenues, respectively. For the three months ended~~revenues. As of March 31, ~~2020, 2~~2022, 3 customers accounted for ~~46.1%~~30.2%, 26.8%, and ~~21.4%, of the Company’s revenues, respectively. As of December 31, 2020, 4 customers accounted for 31.2%, 19.4%, 15.7% and 10.4%~~22.5% of the Company’s accounts receivable, respectively. As of ~~March~~December 31, 2021, 43 customers accounted for ~~39.5%~~21.9%, ~~21.4%~~20.1%, ~~12.8%~~ and ~~12.0%~~16.6% of the Company’s accounts receivable, respectively. The Company’s largest customer in terms of both revenues and accounts receivable in the three months ended March 31, ~~2021~~2022 is a U.S. diversified healthcare company and its affiliated plans.

As of ~~December~~March 31, ~~2020, 2~~2022, 3 vendors accounted for ~~15.9%~~18.0%, 17.1% and ~~24.3%~~10.6% of the Company’s accounts payable, respectively. As of ~~March~~December 31, 2021, ~~3 vendors~~1 vendor accounted for ~~34.8%, 10.8% and 10.0%~~14.0% of the Company’s accounts payable, respectively.

9. Leases

On July 31, 2020, the Company entered into a 61-month lease agreement for office space to use, as necessary, for office administration, lab space and assembly and storage purposes, located in Santa Clara, California. The Company took possession of the leased office space in September 2020, and the lease is effective through September 30, 2025.

As of March 31, ~~2021,~~2022, the remaining lease term is ~~four~~three years and six months with no options to renew. The Company recognized facilities lease expenses of ~~$44~~$22 and ~~$17~~$44 for the three months ended March 31, 2022 and 2021, ~~and March 31, 2020,~~ respectively. ~~The~~

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Notes to Condensed Financial Statements

Unaudited

(In thousands of U.S. Dollars, except share and per share data)

The following table summarizes the future minimum rental payments required under operating leases that had initial or remaining non-cancelable lease terms greater than one year as of March 31, ~~2021:~~2022:


	Total		Total
2021 Remaining period	$	64
2022		87
2022 Remaining period			$	66
2023		90		90
2024		93		93
2025		71		71
Thereafter		—		—
Total undiscounted future minimum lease payments		405		320
Less: present value discount		(23)		(15)
Total lease liabilities		382		305
Lease expense in excess cash payment		(9)		(11)
Total ROU asset	$	373	$	294

As of March 31, ~~2021,~~2022, the Company’s right-of-use (“ROU”) asset was ~~$373,~~$294, which was recorded on the Company’s balance sheet as other ~~current~~noncurrent assets, and the Company’s current and noncurrent lease liabilities were ~~$77~~$81 and ~~$305,~~$224, respectively, which were recorded on the Company’s balance sheet as other short-term liabilities and other long-term liabilities, respectively. As of December 31, ~~2020,~~2021, the Company’s ROU asset was ~~$399,~~$314, which was recorded on the Company’s balance sheet as other ~~current~~noncurrent assets, and the Company’s current and noncurrent lease liabilities were ~~$75~~$80 and ~~$332,~~$245, respectively, which were recorded on the Company’s balance sheet as other short-term liabilities and other long-term liabilities, respectively.

Lease Arrangements

The Company enters into contracts with customers for the Company’s QuantaFlo^® product. The Company has determined these contracts meet the definition of a lease under Topic 842. The lease portfolio primarily consists of operating leases that are short-term in nature (monthly, quarterly or one year, all of which have renewal options). The Company allocates the consideration in a bundled contract with its customers based on relative standalone selling prices of the lease and non-lease components. The Company made an accounting policy election to apply the practical expedient to not separate lease and eligible non-lease components. The lease component is the predominant component and consists of fees charged for use of the equipment over the period of the arrangement. The nature of the eligible non-lease component is primarily software support. The assets associated with these leasing arrangements are separately identified in the Balance Sheet as Assets for Lease and separately disclosed in Note 4 to the Unaudited Condensed Financial Statements.

10. Commitments and Contingencies

Facilities Leases

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~~Semler Scientific, Inc.~~

~~Notes to Condensed Financial Statements~~

~~Unaudited~~

~~(In thousands of U.S. Dollars, except share and per share data)~~

leased office space in September 2020, and the lease is effective through September 30, 2025. See Note 9 to the Unaudited Condensed Financial Statements for the details.

Indemnification Obligations

The Company enters into agreements with customers, partners, lenders, consultants, lessors, contractors, sales representatives and parties to certain transactions in the ordinary course of the Company’s business. These agreements may require the Company to indemnify the other party against third party claims alleging that its product infringes a patent or copyright. Certain of these agreements require the Company to indemnify the other party against losses arising from: a breach of representations or covenants, claims relating to property damage, personal injury or acts or omissions of the Company, its employees, agents or representatives. The Company has also agreed to indemnify the directors and certain of the officers and employees in accordance with the by-laws of the

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Semler Scientific, Inc.
Notes to Condensed Financial Statements

Unaudited

(In thousands of U.S. Dollars, except share and per share data)

Company. These indemnification provisions will vary based upon the nature and terms of the agreements. In many cases, these indemnification provisions do not contain limits on the Company’s liability, and the occurrence of contingent events that will trigger payment under these indemnities is difficult to predict. As a result, the Company cannot estimate its potential liability under these indemnities. The Company believes that the likelihood of conditions arising that would trigger these indemnities is remote and, historically, the Company has not made any significant payment under such indemnification provisions. Accordingly, the Company has not recorded any liabilities relating to these agreements. In certain cases, the Company has recourse against third parties with respect to the aforesaid indemnities, and the Company believes it maintains adequate levels of insurance coverage to protect the Company with respect to potential claims arising from such agreements.

401(K) Plan

Effective January 1, 2022, the Company started to match 50% of employee’s 401(k) deferral up to a maximum of 6% of the employee’s eligible earnings.

Other

The Coronavirus Aid, Relief, and Economic Security Act (the “CARES Act”) provides for an employee retention payroll tax credit for certain employers, which is a refundable tax credit against certain employment taxes equal to 50% of the qualified wages an eligible employer pays to employees after March 12, 2020 and before December 31, 2021. For each employee, wages (including health plan costs) up to $10,000 can be counted to determine the amount of the 50% credit. The Company started claiming this credit on its July 2020 payroll until mid-April 2021 when it determined that it no longer qualified given the change in government restrictions on travel that had impacted its sales activities. The Company’s determination that it qualified to claim the employee retention payroll tax credit is subjective and subject to audit by the Internal Revenue Service (“IRS”). If the IRS were to disagree with the Company’s tax position, it could be required to pay the retention credit claimed, along with penalties. As of December 31, 2021, the Company has claimed $1.24 million in this retention credit.

Litigation

From time to time in the normal course of business, the Company is subject to various legal matters such as threatened or pending claims or litigation. Although the results of claims and litigation cannot be predicted with certainty, the Company does not believe it is a party to any claim or litigation the outcome of which, if determined adversely to it, would individually or in the aggregate be reasonably expected to have a material adverse effect on its results of operations or financial condition.

11. Stock Incentive Plan

The Company’s stock-based compensation program is designed to attract and retain employees while also aligning employees’ interests with the interests of its stockholders. Stock options have been granted to employees under the stockholder-approved 2007 Key Person Stock Option Plan (“2007 Plan”) and stock options and restricted stock have been granted to employees under the stockholder-approved 2014 Stock Incentive Plan (“2014 Plan”). Stockholder approval of the 2014 Plan became effective in September 2014. The 2014 Plan originally provided that the aggregate number of shares of common stock that may be issued pursuant to awards granted under the 2014 Plan may not exceed 450,000 shares (the “Share Reserve”), however in October 2015, the stockholders approved a 1,500,000 increase to the Share Reserve. In addition, the Share Reserve automatically increases on January 1st of each year, for a period of not more than 10 years, beginning on January 1st of the year following the year in which the 2014 Plan became effective and ending on (and including) January 1, 2024, in an amount equal to 4% of the total number of shares of common stock outstanding on December 31st of the preceding calendar year. The Company’s Board of Directors may act prior to January 1st of a given year to provide that there will be no January 1st increase in the Share Reserve for such year or that the increase in the Share Reserve for such year will be a lesser number of shares of common stock than would otherwise occur. In the fourth quarter of 2020, the Board of Directors agreed not to increase the Share Reserve, and accordingly, the Share Reserve did not increase on January 1, 2021. On January 1, ~~2021,~~2022, the Share Reserve increased by ~~268,017 shares due to the automatic 4% increase.~~270,338. The Share Reserve is currently ~~3,312,882~~3,315,203 shares as of March 31, ~~2021.~~

In light of stockholder approval of the 2014 Plan, the Company no longer grants equity awards under the 2007 Plan. As of March 31, 2021, there were 0 shares available for future stock-based compensation grants under the 2007 Plan and 1,523,508 shares of an aggregate total of 3,312,882 shares were available for future stock-based compensation grants under the 2014 Plan.

~~Stock Awards~~

The Company granted fully vested stock awards for an aggregate 5,400 shares of common stock to the non-employee members of the board of directors, employees and 1 non-employee as compensation during the three months ended March 31, 2021. Fair value of these stock awards on grant date was $537.2022.

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Notes to Condensed Financial Statements

Unaudited

(In thousands of U.S. Dollars, except share and per share data)

In light of stockholder approval of the 2014 Plan, the Company no longer grants equity awards under the 2007 Plan. As of March 31, 2022, there were 0 shares available for future stock-based compensation grants under the 2007 Plan and 1,479,103 shares of an aggregate total of 3,315,203 shares were available for future stock-based compensation grants under the 2014 Plan.

Treasury Stock Acquired

On March 14, 2022, the Company’s Board of Directors authorized a share repurchase program under which it may repurchase up to $20.0 million of its outstanding common stock. Under this program the Company may purchase shares on a discretionary basis from time to time through open market purchases, privately negotiated transactions or other means, including through Rule 10b5-1 trading plans or through the use of other techniques such as accelerated share repurchases. The timing and amount of any transactions will be subject to the discretion of the Company based upon market conditions and other opportunities that it may have for the use or investment of its cash balances. The repurchase program has no expiration date, does not require the purchase of any minimum number of shares and may be suspended, modified or discontinued at any time without prior notice. The Company purchased 2,030 shares at a cost of approximately $99 during the three months ended March 31, 2022.

Stock Awards

The Company granted fully vested stock awards of 8,406 shares of common stock to the non-employee members of the board of directors, employees and 1 non-employee as compensation during the three months ended March 31, 2022. Net shares issued after deducting taxes paid on these grants were 6,988. Fair value of these stock awards on grant date was $628. The Company granted fully vested stock awards of 5,400 shares of common stock to the non-employee members of the board of directors, employees and 1 non-employee as compensation during the three months ended March 31, 2021. Fair value of these stock awards on grant date was $537.

Stock Options

Aggregate intrinsic value represents the difference between the closing market value as of March 31, ~~2021~~2022 of the underlying common stock and the exercise price of outstanding, in-the-money options. A summary of the Company’s stock option activity and related information for the three months ended March 31, ~~2021~~2022 is as follows:

Options Outstanding

Weighted

Average

Number of

Weighted

Remaining

Aggregate

Number of

Weighted

Remaining

Aggregate

Stock Options

Average

Contractual

Intrinsic Value

Stock Options

Average

Contractual

Intrinsic Value

Outstanding

Exercise Price

Term (In Years)

(In Thousands)

Outstanding

Exercise Price

Term (In Years)

(In Thousands)

Balance, January 1, 2021

1,451,420

3.25

4.91

131,714

Balance, December 31, 2021

1,356,245

3.30

3.97

119,830

Options exercised

(15,000)

0.61

—

(23,800)

2.58

—

Balance, March 31, 2021

1,436,420

3.28

4.7

149,705

Exercisable as of March 31, 2021

1,414,285

3.20

4.67

147,503

Balance, March 31, 2022

1,332,445

3.31

3.73

61,627

Exercisable as of March 31, 2022

1,332,445

3.31

3.73

61,627

The total compensation cost related to unvested stock option awards not yet recognized was $132 as of March 31, 2021. The weighted average period over which the total unrecognized compensation cost related to these unvested stock awards will be recognized is ~~0.71 years.~~ There were 0 options granted during the three months ended March 31, ~~2021~~2022 or ~~2020.~~2021.

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Semler Scientific, Inc.
Notes to Condensed Financial Statements

Unaudited

(In thousands of U.S. Dollars, except share and per share data)

The Company has recorded an expense of $~~589~~628 and ~~$67~~$589 as it relates to stock-based compensation for the three months ended March 31, ~~2021~~2022 and ~~2020,~~2021, respectively:


	Three months ended March 31,				Three months ended March 31,
	2021		2020		2022		2021
Cost of Revenues	$	—	$	—	$	—	$	—
Engineering and Product Development		32		—		45		32
Sales and Marketing		105		—		172		105
General and Administrative		452		67		411		452
Total	$	589	$	67	$	628	$	589

12. Income Taxes

The Company’s income tax provision for the three months ended March 31, ~~2021~~2022 and March 31, ~~2020 reflect~~2021 was $583 and $1,143, respectively. The income tax provision reflects its estimate of the effective tax rates expected to be applicable for the full year, adjusted for any discrete events that are recorded in the period in which they occurred. The estimates are re-evaluated each quarter based on the estimated tax expense for the full year.

For uncertain tax positions that meet a “more likely than not” threshold, the Company recognizes the benefit of uncertain tax positions in the financial statements. The Company’s practice is to recognize interest and penalties, if any, related to uncertain tax positions in income tax expense in the statements of operations.

The effective tax rate for the three months ended March 31, ~~2021~~2022 was ~~18.99%~~14.79%, compared to ~~22.52%, in~~18.99% for the ~~same period of the prior year.~~three months ended March 31, 2021. The decrease in the effective tax rate for the three months ended March 31, ~~2021~~2022 is primarily related to tax benefits associated with employee share-based compensation ~~plans.~~plans and federal and state research and development credits net of reserves for uncertain tax positions related to these credits.

The effective tax rate for the three months ended March 31, ~~2021~~2022 differed from the U.S. federal statutory rate of 21% primarily due to state income taxes (net of federal benefit) partially offset by tax benefits associated with employee share-based compensation plans and federal and state research and development (“R&D”) credit benefit. The difference between the U.S. Federal statutory rate of 21% and the Company’s effective tax rate of ~~22.52%~~18.99% for the three months ended March 31, ~~2020~~2021 was ~~primarily due to current~~ state income taxes ~~that have no net operating loss to~~(net of federal benefit) partially offset ~~such taxes.~~

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~~Semler Scientific, Inc.~~

~~Notes to Condensed Financial Statements~~

~~Unaudited~~

~~(In thousands of U.S. Dollars, except share~~by tax benefit associated with employee share-based compensation plans and ~~per share data)~~federal and state R&D credit benefit.

As of March 31, ~~2021~~2022, and December 31, ~~2020,~~2021, the Company had ~~$342~~$419 and ~~$341,~~$476, respectively of unrecognized tax benefits, excluding interest and penalties. The Company’s practice is to recognize interest and penalty expenses related to uncertain tax positions in income tax expense, which was 0 for the ~~years~~year ended December 31, ~~2020~~2021 and three months ended March 31, ~~2021.~~2022.

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Semler Scientific, Inc.
Notes to Condensed Financial Statements

Unaudited

(In thousands of U.S. Dollars, except share and per share data)

13. Net Income Per Share, Basic and Diluted

Basic earnings per share (“EPS”) represent net income attributable to common stockholders divided by the weighted average number of common shares outstanding during the measurement period. Diluted EPS represents net income attributable to common stockholders divided by the weighted average number of common shares outstanding during the measurement period while also giving effect to all potentially dilutive common shares that were outstanding during the period using the treasury stock method.

Basic and diluted EPS is calculated as follows:


	Three months ended March 31,										Three months ended March 31,
	2021					2020					2022					2021
	Shares	Net Income		EPS		Shares	Net Income		EPS		Shares	Net Income		EPS		Shares	Net Income		EPS
Basic	6,710,990	$	4,877	$	0.73	6,533,369	$	2,673	$	0.41	6,777,950	$	3,360	$	0.50	6,710,990	$	4,877	$	0.73
Common stock warrants	73,497		0			69,715		0			71,839		0			73,497		0
Common stock options	1,384,888		0			1,462,729		0			1,266,667		0			1,384,888		0
Diluted	8,169,375	$	4,877	$	0.60	8,065,813	$	2,673	$	0.33	8,116,456	$	3,360	$	0.41	8,169,375	$	4,877	$	0.60

The were 0 weighted average shares outstanding of common stock equivalents excluded from the computation of diluted net income per share for the three months ended March 31, ~~2021~~2022 and ~~2020.~~2021.

~~14.~~ ~~Subsequent Events~~

In October 2020, the Company purchased 211,928 shares of common stock of private company #2 from certain sellers in exchange for 40,922 shares of its common stock. On April 1, 2021, the Company exercised its option to “put” these shares of common stock back to the sellers in exchange for the shares of the Company’s common stock originally issued to the sellers. Following this transfer, the Company continues to hold the shares of preferred stock acquired in December 2020.

In April 2021, the Company entered into an agreement with private company #3 to exclusively market and distribute its product line in the United States, including Puerto Rico, except for selected accounts. Under this distribution agreement, the Company agreed to purchase $2.0 million of product inventory. Unless early terminated in accordance with its terms, the exclusive distribution agreement will remain in full force and effect until April 1, 2026, and thereafter there is an option for this agreement to be automatically renewed for additional one-year terms. The Company continues to hold the shares of preferred stock acquired from this company in October 2020.

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Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations.

The following discussion and analysis should be read together with our condensed unaudited financial statements and the related notes appearing elsewhere in this quarterly report on Form 10-Q and with the audited financial statements and notes for the fiscal year ended December 31, ~~2020,~~2021, and the information under the headings “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” in our Annual Report on Form 10-K filed with the SEC on March ~~9, 2021,~~4, 2022, or the Annual Report. This discussion contains forward-looking statements reflecting our current expectations that involve risks and uncertainties. See “Cautionary Note Regarding Forward-Looking Statements” for a discussion of the uncertainties, risks and assumptions associated with these statements. Actual results and the timing of events could differ materially from those discussed in our forward-looking statements as a result of many factors, including those set forth under “Risk Factors” in ~~our~~the Annual Report.

Overview

We are a company providing technology solutions to improve the clinical effectiveness and efficiency of healthcare providers. Our mission is to develop, manufacture and market innovative ~~proprietary~~ products and services that assist our customers in evaluating and treating chronic diseases. In 2011, we began commercializing our first patented and U.S. Food and Drug Administration, or FDA, cleared product, which measured arterial blood flow in the extremities to aid in the diagnosis of peripheral arterial disease, or PAD. In March 2015, we received FDA 510(k) clearance for the next generation version of our product, QuantaFlo,®, which we began commercializing in August 2015.

In ~~September 2020,~~April 2021, we entered into an agreement with a private company to exclusively market and distribute ~~a new~~Insulin Insights, an FDA-cleared software product ~~line~~that recommends optimal insulin dosing for diabetic patients in the United States, including Puerto Rico, ~~and, in September and October 2020, in an effort to provide access to potentially complementary product offerings, we~~except for selected accounts. We made investments in ~~two~~this private ~~companies working~~software company and in another private company whose product, Discern is a test for early Alzheimer’s disease. We continue to develop additional complementary, innovative products in-house, and seek out other ~~product areas.~~arrangements for additional products and services that we believe will bring value to our customers and to our company. We believe our current products and services, and any future products or services that we may offer, position us to provide valuable information to our customer base, which in turn permits them to better guide patient care.

In the three months ended March 31, ~~2021,~~2022, we had total revenues of $14.0 million and net income of $3.4 million, compared to total revenues of $13.2 million and net income of $4.9 million ~~compared to total revenues of $9.4 million and net income of $2.7 million~~ in the same period in ~~2020.~~2021.

Recent Developments

~~Late~~In 2021, variable fee license revenues (fee-per-test), which grew strongly in the first ~~quarter and into~~half of 2021, decreased subsequently in the second ~~quarter~~half of 2020, we experienced decreased test volumes due to COVID-19 related “social distancing” and other executive orders mandating “shelter-in-place” or similar restrictions, which limited patient visits by our customers. As such restrictions have been lifted around2021. We believe this new pattern in the country and non-emergency medical services resumed in late 2020, our business has returned to and even exceeded pre-COVID-19 levels. In the third and fourth quarters of 2020, we experienced even higher test volumes as our customers accelerated usagehome-testing market is due to a ~~backlog~~COVID-19 related timing change in the behavior of ~~untested patients.~~insurance plans when ordering QuantaFlo testing from our health risk assessment customers.

The first quarter results of 2022 support this pattern of testing earlier in the year, as the home-testing market had higher volume of sequential revenues, which grew 67% compared to the fourth quarter of 2021. However, aswe do not know if this newly observed pattern will continue in 2022 or in future years.

We believe that the relatively slower growth in the period-over-period comparison, was due to the COVID-19 pandemic. Our staff and many of our customers and prospects experienced a higher-than-normal rate of employee absence due to illness, which can have a slowing effect on its sales cycle.

As we look forward into ~~2021,~~2022, there is continued uncertainty ~~that the~~as recent ~~roll-back~~outbreaks of new variants have occurred and vaccination rates lag in ~~restrictions will be maintained.~~certain jurisdictions. New, additional or different restrictions could be imposed, which could impact the usage of our product by our ~~customers.~~customers, or further impact the timing of demand for our products. Other customers who have fixed-fee licenses could decide to cancel their licenses if they are not able to use our device as frequently as they had anticipated in light of such restrictions.

~~In September 2020, we entered into an agreement with~~Common Stock Repurchase

On March 14, 2022, our Board of Directors authorized a ~~private company to exclusively market and distribute a new product line in the United States, including Puerto Rico, for~~share repurchase program under which we ~~are currently developing a marketing plan.~~may repurchase up to $20.0 million of our outstanding common stock. Under this ~~distribution agreement,~~program, we ~~agreed~~may purchase shares on a discretionary basis from time to purchase $1.2 million of product inventory. We also agreed to make royalty payments ranging from 0% to 10% of net sales depending on the average net sales price of the distributed products. Unless early terminated in accordance with its terms, the exclusive distribution agreement will remain in full force and effect until December 31, 2024, and thereafter there is an option for this agreement to be automatically renewed for additional 4-year terms. During September 2020, we prepaid for $0.9 million of product inventory, of which we have received $0.3 million as of March 31, 2021.

In September 2020, we acquired a $0.5 million promissory note from a second private company in a new product area. We funded $0.4 million of the note, and the remaining $0.1 million was retained for expense reimbursement. In December 2020, we agreed to the conversion of the $0.5 million promissory note, together with all accrued interest thereon, into shares of the private company’s preferred stock as repayment in full of such promissory note. In October 2020, we purchased 211,928 shares of common stock of such private company from certain sellers in exchange for 40,922 shares of our common stock, and had the right to “put” share shares of common stock back to the sellers in exchange for the return of shares of our common stock issued to them in certain circumstances, including beginning March 31, 2021 for a limited time period. Accordingly, in April 2021, we exercised this right and returned these shares of common stock back to the sellers in exchange for the shares of our common stock originally issued to the sellers. Following this transfer, we continue to hold the shares of preferred stock we acquired from this company in December 2020.

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~~In October 2020,~~time through open market purchases, privately negotiated transactions or other means, including through Rule 10b5-1 trading plans or through the use of other techniques such as accelerated share repurchases. The timing and amount of any transactions will be subject to our discretion and based upon market conditions and other opportunities that we ~~acquired a convertible note in a third private company in a new product area~~may have for ~~a purchase price~~the use or investment of ~~$58,000, which note converted into shares of preferred stock of such private company concurrent with~~ our cash balances. The repurchase program has no expiration date, does not require the purchase of ~~additional~~any minimum number of shares of preferred stock of such private company for $0.3 million. Subsequently, we acquired a $1.5 million convertible promissory note and warrants to purchase shares of common stock of this third privately-held company. We funded $1.4 million of the note, and the remaining $0.1 million was retained for expense reimbursement. In November 2020, the $1.5 million convertible promissory note, together with all accrued interest thereon, converted pursuant to its terms into shares of the private company’s preferred stock as repayment in full of such convertible promissory note. In December 2020, we transferred and sold these shares of preferred stock, along with the warrants to purchase common stock we had acquired from such company in October 2020, to one of our significant stockholders, for a cash purchase price of $1.9 million. Following this transfer, we continue to hold the shares of preferred stock we acquired from this company in October 2020. In April 2021, we entered into an agreement with this private company to exclusively market and distribute their product line in the United States, including Puerto Rico, except for selected accounts. We are currently developing a marketing plan. Under this distribution agreement, we agreed to purchase $2.0 million of product inventory. Unless early terminated in accordance with its terms, the exclusive distribution agreement will remain in full force and effect until April 1, 2026, and thereafter there is an option for this agreement to be automatically renewed for additional one-year terms.

We invested in these three private companies as they are developing products that may allow us to expand our current product offering beyond QuantaFlo® for PAD, in addition to our internal research and development efforts. Their products deal with better chronic disease management and may be ~~used by primary care practitioners, are FDA-cleared~~suspended, modified or ~~equivalent, produced positive clinical data and two~~discontinued at any time without prior notice. We purchased 2,030 shares of our common stock for approximately $0.1 million during the three ~~new products seek to improve aspects or sequelae of the metabolic syndrome.~~

months ended March 31, 2022.

Results of Operations

Three Months Ended March 31, ~~2021~~2022 Compared to Three Months Ended March 31, ~~2020~~2021

Revenues

We had revenues of ~~$13.2~~$14.0 million for the three months ended March 31, ~~2021,~~2022, an increase of ~~$3.8~~$0.8 million, or ~~40%~~6%, compared to ~~$9.4~~$13.2 million in the same period in ~~2020.~~2021. Our revenues are primarily from fees charged to customers for use of our vascular testing products and from sale of accessories used with these products. We recognized revenues of ~~$12.9~~$13.7 million from fees for our vascular testing products for the three months ended March 31, ~~2021~~2022, consisting of ~~$7.2~~$7.9 million from fixed-fee licenses and ~~$5.7~~$5.8 million from variable-fee licenses compared to ~~$9.2~~$12.9 million in the same period of the prior year, consisting of ~~$6.5~~$7.2 million from fixed-fee licenses and ~~$2.7~~$5.7 million from variable-fee licenses. The remainder was from sales of other products, which were $0.3 million ~~for each of~~in both the ~~three months ended~~ periods.~~March 31, 2021 and 2020~~

Revenues from fees for vascular testing products are recognized monthly for each unit installed with a customer, usually billed as a fixed monthly fee, or as a variable monthly fee dependent on usage. The primary reason for the increase in revenues was growth in the number of installed units from both new customers and established customers, which we believe is the result of our sales and marketing efforts.

Operating expenses

We had total operating expenses of ~~$7.2~~$10.0 million for the three months ended March 31, ~~2021,~~2022, an increase of ~~$1.2~~$2.9 million or ~~20%~~41%, compared to ~~$6.0~~$7.1 million in the same period in the prior year. The primary reasons for this change were ~~increases due to~~increased expenses associated with our expanding business, such as increased personnel expense including stock-based compensation and increased headcount, partially offset by payroll tax reductions that were granted by the federal government in the current quarter compared to the same period in the prior year.expense. As a percentage of revenues, operating expenses ~~decreased~~increased to ~~54%~~72% in the first quarter of ~~2021~~2022 as compared to ~~63%~~54% in the prior year period. The changes in the various components of our operating expenses are described below.

Cost of revenues

We had cost of revenues of ~~$1.6~~$1.0 million for the three months ended March 31, ~~2021, an increase~~2022, a decrease of ~~$0.7~~$0.6 million, or ~~86%~~39%, compared to ~~$0.9~~$1.6 million in the same period of the prior year. The primary ~~reasons~~reason for this change ~~were~~was that the prior year period included a non-recurring inventory adjustment for ~~supplies and increased headcount. As a percentage of revenues, cost of revenues increased to 12% in the first quarter of 2021, as compared to 9% in the prior year period.~~supplies.

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Engineering and product development expense

We had engineering and product development expense of ~~$0.7~~$1.1 million for the three months ended March 31, ~~2021, a decrease~~2022, an increase of ~~$0.1~~$0.4 million, or ~~18%~~62%, compared to ~~$0.8~~$0.7 million in the same period of the prior year. The ~~decrease~~increase was primarily due to increased headcount and annual pay increases in line with our business expansion, expiry of COVID-19 related payroll tax ~~credit as well as decreased~~credits received in the prior year and consulting costs associated ~~completed~~with ongoing projects ~~partially offset by higher clinical studies costs and increased headcount.~~to extend QuantaFlo to additional cardiovascular diseases. As a percentage of revenues, engineering and product development expense was 5%8% in the first quarter of ~~2021,~~2022, as compared to 9%5% in the prior year period.

Sales and marketing expense

We had sales and marketing expense of ~~$2.8~~$4.7 million for the three months ended March 31, ~~2021,~~2022, an increase of ~~$0.1~~$1.9 million, or 4%66%, compared to ~~$2.7~~$2.8 million in the same period of the prior year. The increase was primarily due to increased headcount and annual salary increases, ceasing to claim COVID-19 related payroll tax credits received in the prior year period and associated

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expense to serve a continued expansion of customer activities~~partially offset by lower travel expenses and payroll taxes.~~. As a percentage of revenues, sales and marketing expense ~~decreased~~increased to ~~21%~~33% in the first quarter of ~~2021,~~2022, as compared to ~~29%~~21% in the prior year period.

General and administrative expense

We had general and administrative expense of ~~$2.1~~$3.3 million for the three months ended March 31, ~~2021,~~2022, an increase of ~~$0.5~~$1.2 million, or ~~30%~~59%, compared to ~~$1.6~~$2.1 million in the same period of the prior year. The increase was primarily due to the growth in our business, which led to increased expenses including insurance, compensation due to annual salary increases, ceasing to claim COVID-19 related payroll tax credits received in the ~~expansion of board of directors, insurance~~prior year period, information technology related subscriptions, legal, and other professional fees. As a percentage of revenues, general and administrative expense ~~decreased~~increased to ~~16%~~24% in the first quarter of ~~2021,~~2022, as compared to ~~17%~~16% in the prior year period.

Other ~~income/expense~~income

We had total other income of ~~$1,000~~$1.0 thousand for each of the three months ended March 31, 2022 and 2021, ~~compared to other expense of $2,000 in the same period of~~which remained flat even though interest income decreased by $2.0 thousand from the prior ~~year. The increase was primarily~~year period due to ~~miscellaneous~~a gain on sale of old equipment of $1.0 thousand, which was partially offset by credit card merchant fees. In the prior year period interest income ~~and interest income,~~was also partially offset by credit card merchant fees.

~~Pre-tax net~~Net income

~~For the foregoing reasons, we~~We had ~~pre-tax~~ net income of ~~$6.0~~$3.4 million, or $0.50 per basic share and $0.41 per diluted share, for the three months ended March 31, ~~2021, an increase~~2022, a decrease of ~~$2.5~~$1.5 million, or ~~74%~~31%, compared to a ~~pre-tax net income of $3.5 million for the same period of the prior year.~~

~~Income tax expense (benefit)~~

We had income tax expense of $1.1 million for the three months ended March 31, 2021, an increase of $0.3 million or 47%, compared to income tax expense of $0.8 million in the same period of the prior year. The tax expense in the current quarter was due to increased income from operations.

~~Net income~~

~~For the foregoing reasons, we had~~ net income of $4.9 million, or $0.73 per basic share and $0.60 ~~per diluted share, for the three months ended March 31, 2021, an increase of $2.2 million, or 82%, compared to a net income of $2.7 million, or $0.41 per basic share and $0.33~~ per diluted share, for the same period of the prior year.

Liquidity and Capital Resources

We had cash and cash equivalents of ~~$26.5~~$38.4 million aton March 31, ~~2021~~2022 compared to ~~$22.1~~$37.3 million at December 31, ~~2020,~~2021, and total current liabilities of ~~$5.0~~$5.8 million at March 31, ~~2021~~2022 compared to ~~$4.5~~$4.9 million at December 31, ~~2020.~~2021. As of March 31, ~~2021,~~2022, we had working capital of approximately ~~$28.2~~$44.7 million.

Our cash isand cash equivalents are held in a variety of interest and non-interest bearing bank and money market accounts. All cash is readily available and there were no restrictions on cash. We may also hold interest-bearing instruments subject to investment guidelines allowing for holdings in U.S. government and agency securities, corporate securities, taxable municipal bonds,

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commercial paper and money market accounts. In addition, we may also choose to invest some of our cash resources in other entities that may have complementary technologies or product offerings, such as ~~our recent decision to acquire inventory~~prepayment for product licenses for distribution in the United States, including Puerto Rico, of ~~two new product line offerings,~~ Insulin Insights, as well as make ~~two~~ minority investments in other privately-held companies in new product ~~areas.~~areas similar to our investments in Mellitus Health Inc. and Neurodiagnostics Inc.

Operating activities

We generated ~~$4.6~~$1.5 million of net cash from operating activities for the three months ended March 31, ~~2021~~2022, compared to ~~$3.7~~$4.6 million of net cash from operating activities for the same period of the prior year. The change was primarily due to ~~increase of~~lower net income, and higher trade receivables, as well as higher prepaid expenses during the first quarter of 2022, which ~~occurred due~~increased our working capital requirements as compared to ~~growth in our business.~~the prior year period. Non-cash adjustments to reconcile net income to net cash from operating activities provided to net cash of ~~$1.5~~$1.1 million and were primarily due to stock-based compensation expense of $0.6 million, depreciation of $0.2 million, deferred tax ~~expense of $0.6 million, depreciation~~assets of $0.2 million and loss on disposal of assets for lease of $0.1 million. Changes in operating assets and liabilities used ~~$1.7~~$2.9 million of net cash. These changes in operating assets and liabilities included cash used by trade accounts receivable of ~~$1.6~~$1.8 million, prepaid and other expenses of ~~$0.4 million, inventory of $0.3 million and trade payables of $0.2~~$2.0 million, partially offset by cash provided by accrued expenses of ~~$0.7 million and deferred revenue of $0.1~~$0.9 million.

Investing activities

We used $0.3 million of net cash in investing activities for the three months ended March 31, 2022, which reflects funding of purchases of assets for lease of $0.2 million and fixed asset purchases of $0.1 million to support our growing business.

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We used $0.2 million of net cash in investing activities for the three months ended March 31, 2021, which reflects funding of purchases of assets for lease of $0.1 million and fixed asset purchases ~~of $0.1 million to support our growing business.~~

~~We used $0.2 million of net cash in investing activities for the three months ended March 31, 2020, which reflects purchases of assets for lease of $0.1 million and fixed asset purchases of~~ $0.1 million to support our growing business.

Financing activities

We used $0.1 million in net cash from financing activities during the three months ended March 31, 2022, which reflects payment of taxes withheld for stock grants of $0.1 and $0.1 million for the treasury stock acquisition, under our recently announced share purchase program, partially offset by proceeds from exercise of stock options of $0.1 million.

We generated $9,000 in net cash from financing activities during the three months ended March 31, 2021, due to proceeds from exercise of stock options.

~~We generated $3,000~~Critical Accounting Policies and Estimates

The preparation of financial statements in ~~net cash~~conformity with U.S. generally accepted accounting principles requires the use of estimates and assumptions that affect the reported amounts of assets and liabilities, revenues and expenses, and related disclosures in the financial statements. Critical accounting policies are those accounting policies that may be material due to the levels of subjectivity and judgment necessary to account for highly uncertain matters or the susceptibility of such matters to change, and that have a material impact on financial condition or operating performance. While we base our estimates and judgments on our experience and on various other factors that we believe to be reasonable under the circumstances, actual results may differ from ~~financing activities during~~these estimates under different assumptions or conditions. For a discussion of our critical accounting policies and estimates, see “Management’s Discussion and Analysis of Financial Condition and Results of Operations” and notes to the ~~three months~~financial statements in our Annual Report on Form 10-K for the year ended December 31, 2021 filed with the SEC on March 4, 2022. There have been no material changes to these critical accounting policies and estimates through March 31, ~~2020, due to proceeds~~2022 from ~~exercise of stock options.~~

~~Off-Balance Sheet Arrangements~~

~~As of each of March 31, 2021 and~~those discussed in our Annual Report on Form 10-K for the year ended December 31, ~~2020, we had no off-balance sheet arrangements.~~

~~Commitments and Contingencies~~

As of each of March 31, 2021 and December 31, 2020, other than employment/consulting agreements with key executive officers and our facilities lease obligation, we had no material commitments other than the liabilities reflected in our financial statements.2021.

Item 3. Quantitative and Qualitative Disclosures About Market Risk.

Not applicable.

Item 4. Controls and Procedures.

Disclosure Controls and Procedures

We maintain disclosure controls and procedures that are designed to ensure material information required to be disclosed in our reports that we file or submit under the Exchange Act is recorded, processed, summarized, and reported within the time periods specified in the SEC’s rules and forms, and that such information is accumulated and communicated to our management, including our Chief Executive Officer, our Senior Vice President, Finance and Accounting and our Vice President, Finance, as appropriate, to allow timely decisions regarding required financial disclosure. In designing and evaluating the disclosure controls and procedures, we recognized that a control system, no matter how well designed and operated, can provide only reasonable, not absolute, assurance that

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the objectives of the control system are met. Because of the inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within a company have been detected. Management necessarily was required to apply its judgment in evaluating the cost-benefit relationship of possible controls and procedures.

Under the supervision of and with the participation of our management, including our Chief Executive Officer, our Senior Vice President, Finance and Accounting and our Vice President, Finance, we evaluated the effectiveness of our disclosure controls and procedures (as such term is defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act) as of March 31, ~~2021.~~2022. Based upon that evaluation, our Chief Executive Officer, our Senior Vice President, Finance and Accounting and our Vice President, Finance concluded that our ~~internal control over financial reporting, our~~ disclosure controls and procedures were effective. Our management, including our Chief Executive Officer, our Senior Vice President, Finance and Accounting and our Vice President, Finance, has concluded that the consolidated financial statements included in this Quarterly Report on Form 10-Q are fairly stated, in all material respects, in accordance with generally accepting accounting principles in the United States for each of the periods presented herein.

Changes in Internal Control over Financial Reporting

There have been no changes in our internal control over financial reporting that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting during our first fiscal quarter ended March 31, ~~2021.~~2022.

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PART II—OTHER INFORMATION

Item 1. Legal Proceedings.

None.

Item 1A. Risk Factors.

Not applicable.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds.

(a) Recent Sales of Unregistered Securities

None.

(b) Use of Proceeds

Not Applicable.

(c) Issuer Purchases of Equity Securities.

The following table reflects the share repurchase of our common stock.


	(a)	(b)		(c)	(d)
Period	Total number of shares (or units) purchased	Average price paid per share (or unit)		Total number of shares (or units) purchased as part of publicly announced plans or programs	Maximum number (or approximate dollar value) of shares (or units) that may yet be purchased under the plans or programs
March 15, 2022 to March 31, 2022	2,030	$	48.45	2,030	$	19,901,359

On March 14, 2022, our Board of Directors authorized a share repurchase program under which we may repurchase up to $20.0 million of our outstanding common stock. Under this program we may purchase shares on a discretionary basis from time to time through open market purchases, privately negotiated transactions or other means, including through Rule 10b5-1 trading plans or through the use of other techniques such as accelerated share repurchases. The timing and amount of any transactions will be subject to our discretion based upon market conditions and other opportunities that we may have for the use or investment of our cash balances. The repurchase program has no expiration date, does not require the purchase of any minimum number of shares and may be suspended, modified or discontinued at any time without prior notice.

Item 3. Defaults upon Senior Securities.

None.

Item 4. Mine Safety Disclosures.

Not applicable.

Item 5. Other Information.

~~Not applicable.~~None.

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Item 6. Exhibits.

Exh. No.		Exhibit Name
3.1		Amended and Restated Certificate of Incorporation (incorporated by reference to Exhibit 3.1 of our Form 8-K filed with the Securities and Exchange Commission on November 2, 2015).
3.2		Second Amended and Restated Bylaws (incorporated by reference to Exhibit 3.1 of our Form 8-K filed with the Securities and Exchange Commission on October 26, 2021).
31.1		Rule 13a-14(a) Certification of Principal Executive Officer of Registrant
31.2		Rule 13a-14(a) Certification of Principal Financial Officer of Registrant
32.1*		Section 1350 Certification

101.INS		XBRL Instance Document - the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document.
101.SCH		Inline XBRL Taxonomy Extension Schema
101.CAL		Inline XBRL Taxonomy Extension Calculation Linkbase
101.DEF		Inline XBRL Taxonomy Extension Definition Linkbase
101.LAB		Inline XBRL Taxonomy Extension Label Linkbase
101.PRE		Inline XBRL Taxonomy Extension Presentation Linkbase
104		The cover page from Semler Scientific's Quarterly Report on Form 10-Q for the three months ended March 31, ~~2021~~2022 is formatted in Inline XBRL and it is contained in Exhibit 101

* These certifications are furnished to the SEC pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 and are deemed not filed for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, nor shall they be deemed incorporated by reference in any filing under the Securities Act of 1933, except as shall be expressly set forth by specific reference in such filing.

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

May ~~7, 2021~~6, 2022	SEMLER SCIENTIFIC, INC.

	By:	/s/ Douglas Murphy-Chutorian, M.D.
		Douglas Murphy-Chutorian, M.D.
		Chief Executive Officer

	By:	/s/ Andrew B. Weinstein
		Andrew B. Weinstein
		Senior Vice President, Finance and Accounting

		Page
Part I.	Financial Information	1

Item 1.	Financial Statements	1
Item 2.	Management’s Discussion and Analysis of Financial Condition and Results of Operations	15
Item 3.	Quantitative and Qualitative Disclosures about Market Risk	18
Item 4.	Controls and Procedures	18

Part II.	Other Information	19

Item 1.	Legal Proceedings	19
Item 1A.	Risk Factors	19
Item 2.	Unregistered Sales of Equity Securities and Use of Proceeds	19
Item 3.	Defaults upon Senior Securities	19
Item 4.	Mine Safety Disclosures	19
Item 5.	Other Information	19
Item 6.	Exhibits	20

Signatures		21