Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes☒ No ☐☐

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes☒ No ☐☐

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growth company. See the definitions of ~~“large~~"large accelerated filer,~~” “accelerated filer”~~" "accelerated filer", ~~“smaller~~"smaller reporting company,”" and ~~“emerging~~"emerging growth ~~company”~~company" in Rule 12b-2 of the Exchange Act.

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐ No ☒☒

As of ~~November 11, 2021,~~August 5, 2022, there were ~~102,293,271~~135,802,201 Ordinary Shares, nil par value, of Quotient Limited outstanding.

This Quarterly Report on Form 10-Q, and exhibits thereto, contains estimates, predictions, opinions, projections and other statements that may be interpreted as “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, or the Securities Act, and Section 21E of the Securities Exchange Act of 1934, as amended, or the Exchange Act, that involve substantial risks and uncertainties. The forward-looking statements are contained principally in Part I, Item 2: ~~“Management’s~~"Management’s Discussion and Analysis of Financial Condition and Results of ~~Operations”~~Operations" and are also contained elsewhere in this Quarterly Report. Forward-looking statements can be identified by words such as “strategy,” “objective,” “anticipate,” “believe,” “estimate,” “expect,” “intend,” “may,” “plan,” “predict,” “project,” “target,” “potential,” “will,” “would,” “could,” “should,” “continue,” “contemplate,” “might,” “design”"strategy," "objective," "anticipate," "believe," "estimate," "expect," "intend," "may," "plan," "predict," "project," "target," "potential," "will," "would," "could," "should," "continue," "contemplate," "might," "design" and other similar expressions, although not all forward-looking statements contain these identifying words. Although we believe that we have a reasonable basis for each forward-looking statement contained in this Quarterly Report, we caution you that these statements are based on a combination of facts and factors currently known by us and our expectations of the future, about which we cannot be certain, and are subject to numerous known and unknown risks and uncertainties.

You should also refer to the various factors identified in this and other reports filed by us with the Securities and Exchange Commission, or SEC, including but not limited to those discussed in the section entitled ~~“Risk Factors”~~"Risk Factors" in our Annual Report on Form ~~10-K/A~~10-K for the year ended March 31, ~~2021,~~2022, for a discussion of other important factors that may cause our actual results to differ materially from those expressed or implied by our forward-looking statements. As a result of these factors, we cannot assure you that the forward-looking statements in this Quarterly Report will prove to be accurate. Further, if our forward-looking statements prove to be inaccurate, the inaccuracy may be material. In light of the significant uncertainties in these forward-looking statements, you should not regard these statements as a representation or warranty by us that we will achieve our objectives and plans in any specified time frame, or at all. The forward-looking statements in this Quarterly Report represent our views only as of the date of this Quarterly Report. Subsequent events and developments may cause our views to change. While we may elect to update these forward-looking statements at some point in the future, we undertake no obligation to publicly update any forward-looking statements, except as required by law. You should, therefore, not rely on these forward-looking statements as representing our views as of any date subsequent to the date of this Quarterly Report.

Access to our Annual Report on Form 10-K, Quarterly Reports on Form 10-Q, Current Reports on Form 8-K, and amendments to these reports filed with or furnished to the SEC, may be obtained through the investor section of our website at www.quotientbd.com as soon as reasonably practical after we electronically file or furnish these reports. We do not charge for access to and viewing of these reports. Information on our website, including in the investor section, is not part of this Quarterly Report on Form 10-Q or any of our other securities filings unless specifically incorporated herein or therein by reference. In addition, our filings with the SEC may be accessed through the SEC’s website at www.sec.gov. All statements made in any of our securities filings, including all forward-looking statements or information, are made as of the date of the document in which the statement is included, and we do not assume or undertake any obligation to update any of those statements or documents unless we are required to do so by law.

(Expressed in thousands of U.S. Dollars — except for share data and per share data)

The accompanying notes form an integral part of these condensed consolidated financial statements.

(Expressed in thousands of U.S. Dollars — except for share data and per share data)

The accompanying notes form an integral part of these condensed consolidated financial statements.

CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS’ EQUITY (DEFICIT) (unaudited)

The accompanying notes form an integral part of these condensed consolidated financial statements.

~~The accompanying notes form an integral part of these condensed consolidated financial statements.~~

(Expressed in thousands of U.S. Dollars — except for share data and per share data, unless otherwise stated)

Note 1. Description of Business and Basis of Presentation

Description of Business

The principal activity of Quotient Limited (the ~~“Company”~~"Company") and its subsidiaries (the ~~“Group”~~"Group") is the development, manufacture and sale of products for the global transfusion diagnostics market. Products manufactured by the Group are sold to hospitals, blood banking operations and other diagnostics companies worldwide.

Basis of Presentation

The condensed consolidated financial statements have been prepared pursuant to the rules and regulations of the Securities and Exchange Commission ~~(“SEC”~~("SEC") and are unaudited. In accordance with those rules and regulations, they do not include all of the information and footnotes required by accounting principles generally accepted in the United States ~~(“GAAP”~~("GAAP") for complete financial statements.

In the opinion of management, the accompanying unaudited condensed consolidated financial statements contain all normal and recurring adjustments considered necessary to present fairly the financial position, results of operations, changes in shareholders’ equity and cash flows for the interim periods presented. The March 31, ~~2021~~2022 balance sheet was derived from audited financial statements, but does not include all disclosures required by GAAP. However, the Company believes that the disclosures are adequate to make the information presented not misleading. The financial statements should be read in conjunction with the audited consolidated financial statements at and for the year ended March 31, ~~2021~~2022 included in the Company’s Annual Report on Form ~~10-K/A~~10-K for the year then ended. The results of operations for the three month ~~and six month~~ period ended ~~September~~June 30, ~~2021~~2022 are not necessarily indicative of the results of operations that may be expected for the year ending March 31, ~~2022~~2023 and any future period.

The Company has incurred net losses and negative cash flows from operations in each year since it commenced operations in 2007 and had an accumulated deficit of ~~$654.3~~$763.9 million as of ~~September~~June 30, ~~2021.~~2022. At ~~September~~June 30, ~~2021,~~2022, the Company had available cash holdings and ~~short-term~~ investments of ~~$141.8~~$63.2 million. These holdings include $20.8 million of investments, which is net of impairment and foreign currency impacts, held in 2 short-term investment funds with Credit Suisse Asset Management (‘CSAM’) that are currently in the process of being liquidated. The remaining short-term investments to be liquidated are subject to significant valuation uncertainty.

The Company recognized an impairment of $2.3 million related to one of the funds invested with CSAM for the year ended March 31, 2021. No additional information was received during the quarter ended September 30, 2021 that would indicate further impairments were required.

~~While the timing and amount of further payments are not clear (see Note 6), the Company estimates that it will receive the remaining distributions~~has expenditure plans over the ~~next year. Should~~twelve months from the date these financial statements are issued that not be the case, the Company has identified compensating, controllable operating expense and discretionary capital expenditure mitigation measures which would not adversely impact strategic objectives.

~~The Company’s existing available~~exceed its current cash and ~~short-term~~ investment balances, ~~are adequate~~raising substantial doubt about its ability to ~~meet its forecasted cash requirements for the next twelve months and accordingly the financial statements have been prepared on the~~continue as a going ~~concern basis.~~

~~Thereafter, the~~concern. The Company expects to fund its operations, including the ongoing development of MosaiQ through successful field trial completion, achievement of required regulatory authorizations and commercialization, from existing available cash and ~~short-term~~ investment balances, the sale of rights and other assets, and the issuance of new equity or debt. The Company’s Directors are confident in the availability of these funding sources and accordingly have prepared the financial statements on the going concern basis. However, there can be no assurance the Company will be able to obtain adequate financing when necessary and the terms of any financing may not be advantageous to the Company and may result in dilution to its shareholders.

Use of Estimates

The preparation of unaudited condensed consolidated financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the amounts reported in the unaudited condensed consolidated financial statements and accompanying notes. ~~Actual results could differ from these estimates.~~

~~On March 11, 2020, the World Health Organization declared the outbreak of a strain of novel coronavirus disease, COVID-19, a global pandemic.~~ The extent to which the COVID-19 pandemic will impact the Company’s business, operations and financial results will depend on future developments and numerous evolving factors, which are highly uncertain and difficult to predict. As of the date of issuance of these unaudited condensed consolidated financial statements, the Company is not aware of any specific event or circumstance that would require the Company to further update estimates, judgments or revise the carrying value of any assets or liabilities. These estimates may change, as new events occur and additional information is obtained, and are recognized in the condensed consolidated financial statements as soon as they become known. Actual results could differ from those estimates and any such differences may be material to the Company’s condensed consolidated financial statements.

Note 2. Summary of Significant Accounting Policies

Restricted Cash

Restricted cash comprised ~~$8.0 and $8.7~~$8.0 million ~~respectively~~ at ~~September~~June 30, ~~2021~~2022 and March 31, ~~2021,~~2022, held in a cash reserve account pursuant to the indenture governing the Company’s ~~12%~~12% Senior Secured Notes (“("the Secured ~~Notes”~~Notes") and ~~$302 and $324~~$0.7 million held at ~~September~~June 30, ~~2021~~2022 and March 31, ~~2021, respectively,~~2022, held in a restricted account as security for the property rental obligations of the Company’s Swiss subsidiary.

Concentration of Credit Risks and Other Uncertainties

On March 12, 2021, the Company announced that 2 funds managed by CSAM in which the Company had invested an aggregate of approximately $110.35 million had suspended redemptions. The investments into these funds were made in accordance with the Company’s investment policy of making individual investments with a minimum of an A rating from a leading credit-rating agency. Each fund holds short-term credit obligations of various obligors. According to a press release issued by CSAM, redemptions in the funds were suspended because “certain part of the Subfunds’ assets is currently subject to considerable uncertainties with respect to their accurate valuation.” CSAM subsequently began a liquidation of the funds. Pursuant to the liquidation, the Company has already received cash distributions of approximately $86.8 million. Based on information provided by Credit Suisse, the Company expects to receive further cash distributions from the funds in the next several months; however, there can be no assurance as to the timing or amount of any such distributions. ~~Of this $86.8 million, the Company received $11.2 million of distributions during the three month period ended September 30, 2021, and $29.7 million during the six months September 30, 2021.~~ While Credit Suisse has advised that the credit assets held by the funds are covered by insurance that potentially will be available to cover losses the funds would incur if any of the obligors on the funds’ credit assets were to default, the Company does not know if the funds will incur losses (net of insurance) on the credit assets held by the funds.

On April 22, 2021, Credit Suisse published its FY 2021 Q1 press release with commentary related to the supply chain financing funds. Notably, Credit Suisse indicated that the investors in the funds should assume losses will be incurred.

The Company evaluated the investments in the CSAM managed funds for impairment, in accordance with ASC 321-10-35, Investments – Equity Securities, and determined that its investment in ~~one~~two of the funds ~~was~~were impaired. ~~The Company recognized an impairment expense of $2.3 million during the year ended March 31, 2021 related to this fund.~~ ~~No additional information was received during~~During the quarter ended ~~September~~June 30, ~~2021,~~2022, we determined that a further impairment of $1.0 million was required related to litigation costs expected to be incurred by Credit Suisse which Credit Suisse communicated would ~~indicate further impairments were required.~~be deducted from investor recoveries.

The Company views the liquidation of the supply chain finance funds as a fluid situation with a significant amount of valuation uncertainty. The Company will closely monitor the situation and in the event that new information is released that provides valuation clarity, it will evaluate the accounting implications accordingly. The Company believes, and has advised Credit Suisse, that any losses on the supply chain funds should be borne by Credit Suisse. The Company will pursue all available options to recoup the full amount of its investment in the supply chain funds prior to liquidation.

The Company’s main financial institutions for banking operation held all of the Company’s cash and cash equivalents as of ~~September~~June 30, ~~2021~~2022 and March 31, ~~2021.~~2022.

Revenue Recognition

In the three ~~and six~~ month period ended ~~September~~June 30, ~~2021,~~2022, revenue recognized from performance obligations related to prior periods was not material. Other than those described in Note 1 to the audited annual Consolidated Financial statements for the year ended March 31, ~~2021,~~2022, there were no other material revenues to be recognized in future periods related to remaining performance obligations at ~~September~~June 30, ~~2021.~~2022.

The Company’s other significant accounting policies are described in Note 1 to the audited annual Consolidated Financial Statements for the year ended March 31, ~~2021~~2022 included in our Annual Report on Form ~~10-K/A~~10-K for the fiscal year ended March 31, ~~2021.~~2022.

~~Recently Adopted Accounting Pronouncements~~

In August 2020, the FASB issued ASU 2020-06, Debt - Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging - Contracts in Entity’s Own Equity (Subtopic 815-40): Accounting for Convertible Instruments and Contracts in an Entity’s Own Equity (“ASU 2020-06”). The guidance simplifies the complexity associated with applying U.S. GAAP for certain financial instruments with characteristics of liabilities and equity. More specifically, the amendments focusThere have been no significant changes to these policies that have had a material impact on the ~~guidance for~~Company's condensed consolidated financial statements and related notes.

~~- 9 -~~

~~convertible instruments and derivative scope exception for contracts in an entity’s own equity. The new guidance also requires the if-converted method~~Recently Issued Pronouncements

There are no recently issued accounting standards that are expected to be applied for all convertible instruments and requires additional disclosures. ASU 2020-06 is effective for fiscal years beginning after December 15, 2023, including interim periods within those fiscal years. Early adoption is permitted, but no earlier than fiscal years beginning after December 15, 2020, including interim periods within those fiscal years. The Company adopted this guidance on April 1, 2021 using the modified retrospective approach and it did not have a material impact on ~~its~~our condensed consolidated financial ~~statements. See Note 3 “Debt” for further detail on the Company’s accounting policy for convertible debt instruments.~~statements.

Note 3. Debt

Total debt comprises:


	September 30, 2021			March 31, 2021			June 30, 2022			March 31, 2022
Secured Notes	$	132,917		$	145,000		$	132,917		$	132,917
Debt discount, net of amortization		(8,617	)		(11,127	)		(12,679	)		(13,854	)
Deferred debt costs, net of amortization		(3,228	)		(4,261	)		(2,420	)		(2,678	)
Carrying value Secured Notes		121,072			129,612			117,818			116,385

Royalty liability		36,605			39,614			40,343			40,076

Convertible Notes		105,000			—			105,000			105,000
Debt discount, net of amortization		(27,204	)		—			(23,801	)		(24,968	)
Deferred debt costs, net of amortization		(3,509	)		—			(3,012	)		(3,180	)
Carrying value Convertible Notes		74,287			—			78,187			76,852
Total Debt	$	231,964		$	169,226		$	236,348		$	233,313

The Company’s debt at ~~September~~June 30, ~~2021~~2022 and March 31, 2022 comprises the Secured Notes, the royalty liability, and the Convertible Notes. ~~The Company’s debt at March 31, 2021 comprised the~~

Secured Notes ~~and the royalty liability. As of March 31, 2021, the Company’s long term debt, included $24,167 of principal payments due within 1 year which is classified as current within the balance sheet.~~

~~Secured Notes~~- 8 -

On October 14, 2016, the Company completed the private placement of up to ~~$120~~$120 million aggregate principal amount of the Secured Notes and entered into an indenture governing the Secured Notes with the guarantors party thereto and U.S. Bank National Association, a national banking association, as trustee and collateral agent. The Company issued ~~$84~~$84 million aggregate principal amount of the Secured Notes on October 14, 2016 and an additional ~~$36~~$36 million aggregate principal amount of the Secured Notes on June 29, 2018. On December 18, 2018, the Company also completed certain amendments to the indenture governing the Secured Notes. The amendments included an increase to the aggregate principal amount of Secured Notes that can be issued under the indenture from ~~$120~~$120 million to up to ~~$145~~$145 million following the European CE Marking of the Company’s initial MosaiQ IH Microarray. On April 30, 2019, the Company was notified that it had received the European CE Marking of the initial MosaiQ IH Microarray and, on May 15, 2019, the Company issued the additional ~~$25~~$25 million of Secured Notes.

The obligations of the Company under the indenture and the Secured Notes are unconditionally guaranteed on a secured basis by the guarantors, which include all the Company’s subsidiaries, and the indenture governing the Secured Notes contains customary events of default. The Company and its subsidiaries must also comply with certain customary affirmative and negative covenants, including a requirement to maintain six-months of interest in a cash reserve account maintained with the collateral agent. Upon the occurrence of a Change of Control, subject to certain conditions, or certain Asset Sales (each, as defined in the indenture), holders of the Secured Notes may require the Company to repurchase for cash all or part of their Secured Notes at a repurchase price equal to ~~101%~~101% or ~~100%~~100%, respectively, of the principal amount of the Secured Notes to be repurchased, plus accrued and unpaid interest to the date of repurchase.

The Company paid $8.7 million of the total proceeds of the three issuances into the cash reserve account maintained with the collateral agent under the terms of the indenture, $1.5 million of which related to the third issuance on May 15, 2019. Following the April 15, 2021 repayment of the Secured Notes the balance held in the cash reserve account was reduced to $8.0 million.

Interest on the Secured Notes accrues at a rate of ~~12%~~12% per annum and is payable semi-annually on April 15 and October 15 of each year commencing on April 15, ~~2017.~~2017. On April 15, 2021, the Company made a ~~$12.1~~$12.1 million principal payment on the Secured Notes. Additionally, principal payments were due on each April 15 and October 15 until April 15, 2024 pursuant to a fixed amortization schedule.

~~- 10 -~~

The Company paid $8.7 million of the total proceeds of the three issuances into the cash reserve account maintained with the collateral agent under the terms of the indenture. Following the April 15, 2021 repayment of the Secured Notes the balance held in the cash reserve account was reduced to $8.0 million.

On October 13, 2021, the Company received consents from all of the holders (the ~~“Consenting Holders”~~"Consenting Holders") of its Secured Notes issued pursuant to the Indenture, dated as of October 14, 2016 (as subsequently amended, the ~~“Indenture”~~"Indenture"), by and among the Company, the guarantors party thereto and U.S. Bank National Association, a national banking association, as trustee and collateral agent, to certain amendments to the indenture governing the Secured Notes (the ~~“Indenture Amendments”~~"Indenture Amendments") pursuant to the fourth supplemental indenture, dated as of October 13, 2021 (the ~~“Fourth~~"Fourth Supplemental ~~Indenture”~~Indenture").

The Indenture Amendments ~~include~~included an 18-month extension of the final maturity of the Secured Notes to October 2025 and a revision of the Notes’ principal amortization schedule (which previously required semi-annual payments of principal beginning April 2021) to commence April 2023. The revised amortization schedule will defer approximately $60 million of principal payments previously required to be made between April 2021 and April 2023. schedule. The Indenture Amendments also ~~change~~changed the redemption prices for Notes redeemed pursuant to the optional redemption provisions of the Indenture. The Secured Notes may be redeemed from and after October 14, 2021 at redemption prices beginning at ~~106%~~106% of par and declining over time to ~~100.0%~~100.0% for redemptions occurring from and after April 14, 2024.

The interest rate on the Secured Notes and the financial and other covenants in the Indenture ~~remain~~remained unchanged.

In consideration for the Consenting Holders’ consents to the Indenture Amendments, the Company agreed among other things to issue them (i) an aggregate of 932,772 of the Company’s ordinary shares, nil par value per share (the ~~“Consent Shares”~~"Consent Shares") and (ii) 5-year warrants to purchase an aggregate of 1,844,020 of the Company’s ordinary shares for $4$4 per share (the ~~“Consent Warrants”~~"Consent Warrants"). The Company ~~agreed to file~~filed a registration statement with the SEC covering resales of the Consent Shares and the shares issuable on exercise of the Consent Warrants. The fair value of Consent Shares not yet issued are included in accrued expenses and other current liabilities and the fair value of Consent Warrants is included in derivative liabilities within our condensed consolidated balance sheet. Changes in fair value are recognized within Other, net in the accompanying consolidated financial statements.

On July 6, 2022, the Company received consents from the Consenting Holders of its Secured Notes issued pursuant to the Indenture, dated as of October 14, 2016, by and among the Company, the guarantors party thereto and U.S. Bank National Association, a national banking association, as trustee and collateral agent, to Indenture Amendments pursuant to the sixth supplemental indenture, dated as of July 6, 2022 (the "Sixth Supplemental Indenture").

The Sixth Supplemental Indenture includes a change to the amortization payment schedule of the Secured Notes from requiring semi-annual payments ranging from $12.1 million to $24.2 million beginning in April 2023, to requiring quarterly payments of $2.5 million beginning on July 15, 2024 and ending on July 15, 2025, with the remaining principal balance due on October 15, 2025, which will reduce expected amortization payments by $93.0 million over the next 36 months prior to the payment of the remaining principal balance at maturity. It removes the requirement that we maintain a cash reserve account for the benefit of holders of the Secured Notes, and adds a covenant that we maintain a minimum liquidity of at least $8.0 million, comprised of cash and certain other eligible investments, as of the end of each fiscal quarter. Provides that 40% of the net cash proceeds from a sale of all or a material portion of our Alba business, subject to certain exceptions, will be applied to repay Senior Secured Notes and the remaining 60% may be used by us to fund operating expenses, capital expenditures and other investments permitted by the Sixth Supplemental Indenture. We have

- 9 -

also agreed that the holders of the Secured Notes will be entitled to appoint an observer to our board of directors. In addition, the debt incurrence covenant in the indenture governing our Convertible Notes has been amended to reduce our ability to incur indebtedness under certain baskets by the amount of any repayment of the Secured Notes as described above.

In consideration for the Consenting Holders’ consents to the Indenture Amendments, the Company agreed among other things to issue them 5-year warrants to purchase an aggregate of 8,494,595 of the Company’s ordinary shares for $0.75 per share (the "Consent Warrants"). The Company plans to file a registration statement with the SEC covering resales of the shares issuable on exercise of the Consent Warrants.

The new principal amortization schedule of the Secured Notes ~~will be~~is as follows:

~~Payment Date~~	~~Amount~~
~~April 15, 2023~~		~~$12,100,000~~
~~October 15, 2023~~		~~$18,100,000~~
~~April 15, 2024~~		~~$24,200,000~~
~~October 15, 2024~~		~~$24,200,000~~
~~April 15, 2025~~		~~$24,200,000~~
~~October 15, 2025~~		~~The principal balance then outstanding~~


Payment Date	Amount
July 15, 2024	$	2,500
October 15, 2024		2,500
January 1, 2025		2,500
April 15, 2025		2,500
July 15, 2025		2,500
October 15, 2025	The principal balance then outstanding

Royalty liability

In connection with the three issuances of the Secured Notes as well as the December 2018 amendment of the related indenture, the Company has entered into royalty rights agreements, pursuant to which the Company has agreed to pay ~~3.4%~~3.4% of the aggregate net sales of MosaiQ instruments and consumables made in the donor testing market in the United States and the European Union. The royalties will be payable beginning on the date that the Company or its affiliates makes its first sale of MosaiQ consumables in the donor testing market in the European Union or the United States and will end on the last day of the calendar quarter in which the eighth anniversary of the first sale date occurs. The royalty rights agreements are treated as sales of future revenues that meet the requirements of Accounting Standards Codification Topic 470 ~~“Debt”~~"Debt" to be treated as debt. The future cash outflows under the royalty rights agreements were estimated at ~~$65.3~~$71.8 million at ~~September~~June 30, ~~2021,~~2022, and ~~$106.5~~$76.8 million at March 31, ~~2021.~~2022. The decrease in value of the future cash outflows under the royalty rights agreement at June 30, 2022, is driven by a change in the expected first date of sales to be made in Europe and the United States, to an earlier date, while not modifying our forecast for later periods. The royalty rights agreements are accounted for separately as freestanding financial instruments. Consideration received for the debt and royalty rights was allocated to each component on a relative fair value basis. The difference between the relative fair value of the royalty rights agreements and the principle on the Secured Notes is accounted for as debt discount and amortized through non-cash interest expense over the life of the Secured Notes. Estimating the future cash outflows under the royalty rights agreements requires the Company to make certain estimates and assumptions about future sales of MosaiQ products. These estimates of the magnitude and timing of MosaiQ sales are subject to significant variability due to the current status of development of MosaiQ products, and thus are subject to significant uncertainty. Therefore, the estimates are likely to change as the Company gains experience of marketing MosaiQ, which may result in future adjustments to the accretion of the interest expense and amortized cost based carrying value of the royalty liability. ~~The decrease in value of the future cash outflows under the royalty rights agreement as of September 30, 2021 is driven by a shift of expected revenues towards markets outside of Europe and the USA.~~

~~Convertible Notes~~

Convertible Notes

On May 26, 2021 the Company issued ~~$95.0~~$95.0 million aggregate principal amount of convertible senior notes and on June 2, 2021, the Company issued an additional ~~$10.0~~$10.0 million aggregate principal amount of convertible senior notes in connection with the original ~~$95.0~~$95.0 million (collectively the ~~" Convertible~~"Convertible Notes"). The Convertible Notes bear interest at an annual rate of ~~4.75%~~4.75%. The Convertible Notes will mature on May 26, ~~2026. At September 30, 2021, accrued~~2026. Accrued interest of ~~$1.7 million~~$635 and $469 is included in accrued expenses and other current liabilities in the accompanying consolidated financial ~~statements.~~statements at June 30, 2022 and June 30, 2021 respectively.

~~- 11 -~~

At any time before the close of business on the second business day immediately before the maturity date, holders of the Convertible Notes can convert the Convertible Notes either in whole or in part into the Company’s ordinary shares at an initial conversion rate of 176.3668 ordinary shares per ~~$1,000~~$1,000 principal amount of the Convertible Notes, subject to customary anti-dilution adjustments.

The Convertible Notes are accounted for in accordance with ASC 470-20, Debt with Conversion and Other Options (“("ASC ~~470-20”~~470-20") and ASC 815-40, Contracts in Entity’s Own Equity (“("ASC ~~815-40”~~815-40"). Based upon the Company’s analysis, it was determined the Convertible Notes contain embedded features that need to be separately accounted for as a derivative liability component. The proceeds received from the issuance of the convertible debt instruments were bifurcated and recorded as a liability within ~~convertible loan derivatives~~derivative liabilities in the consolidated balance sheet. The convertible loan derivative is measured at fair value and changes are recognized within ~~other, net in~~ the accompanying consolidated financial ~~statements.~~
statements within Other, net.

The Company incurred approximately ~~$3.7~~$3.7 million of debt issuance costs relating to the issuance of the Convertible Notes, which were recorded as a reduction to the Convertible Notes on the consolidated balance sheet, ~~0ne~~0ne of the issuance costs were attributable

- 10 -

to the derivative component. The debt issuance costs and the debt discount are being amortized and recognized as additional interest expense over the expected life of the Convertible Notes using the effective interest rate method. We determined the expected life of the debt is equal to the five-yearterm of the ~~Senior~~ Convertible Notes. The effective interest rate on the Convertible Notes is ~~12.9%~~12.9%. For the ~~six months~~three month period ended ~~September~~June 30, ~~2021,~~2022, the total interest expense was ~~$3.4~~$2.6 million with coupon interest of ~~$1.7~~$1.2 million and the amortization of debt discount and issuance costs of ~~$1.7~~$1.4 million. For the three ~~months~~month period ended ~~September 30,2021,~~June 30, 2021, the total interest expense was ~~$2.5~~$0.9 million with coupon interest of ~~$1.3~~$0.5 million and the amortization of debt discount and issuance costs of ~~$1.2~~$0.4 million.

Note 4. Consolidated Balance Sheet Detail

Inventory

The following table summarizes inventory by category for the dates presented:


	September 30, 2021		March 31, 2021		June 30, 2022		March 31, 2022
Raw materials	$	9,990	$	9,189	$	9,873	$	10,228
Work in progress		9,488		9,105		7,207		7,154
Finished goods		5,536		3,717		5,002		4,654
Total inventories	$	25,014	$	22,011	$	22,082	$	22,036

Inventory at ~~September~~June 30, ~~2021~~2022 included ~~$7,237~~$6,916 of raw materials, ~~$4,706~~$4,511 of work in progress and ~~$3,742~~$3,619 of finished goods related to the MosaiQproject. Inventory at March 31, ~~2021,~~2022, included ~~$6,829~~$6,761 of raw materials, ~~and $4,321~~$4,252 of work in progress and ~~$1,465~~$2,758 of finished goods related to the MosaiQproject. Included in other accrued expenses at June 30, 2022, is $478 of projected losses on firm purchase commitments recorded in other accrued expenses.

Accrued expenses and other current liabilities

Accrued expenses and other current liabilities consist of the following:


	June 30, 2022		March 31, 2022
Accrued legal and professional fees	$	3,198	$	1,254
Accrued interest		4,001		9,235
Goods received not invoiced		2,415		1,304
Accrued capital expenditure		318		193
Other accrued expenses		2,883		3,743
Total accrued expenses and other current liabilities	$	12,815	$	15,729

September 30,
2021

March 31,
2021

Accrued legal and professional fees

$
1,192

$
1,005

Accrued interest

9,110

8,009

Goods received not invoiced

2,418

1,722

Accrued capital expenditure

106

1,201

Other accrued expenses

2,120

2,072

Total accrued expenses and other current liabilities

$
14,946

$
14,009

~~Note 5. Commitments and contingencies~~

~~Hedging arrangements~~

The Company’s subsidiary in the United Kingdom (“UK”) has entered into 3 contracts to sell $500 in each calendar month from October 2021 through December 2021 at £1:$1.3090 and 3 contracts to sell $500 in each calendar month from January 2022

~~- 12 -~~

through March 2022 at £1:$1.3735, as hedges of its U.S. dollar denominated revenues. The fair values of these contracts in place at September 30, 2021, and similar contracts in place at March 31, 2021, amounted to assets of $12 and $355, respectively.

The foreign currency forward contracts were entered into to mitigate the foreign exchange risk arising from the fluctuations in the value of U.S. dollar denominated transactions entered into by our UK subsidiary. These foreign currency forward contracts are designated as cash flow hedges and are carried on the Company’s balance sheet at fair value with the effective portion of the contracts’ gains or losses included in accumulated other comprehensive loss and subsequently recognized in revenue/expense in the same period the hedged items are recognized.

Note 6.5. Fair value measurement

The following table summarizes the Company’s assets and liabilities that are measured at fair value on a recurring basis, by level, within the fair value hierarchy:


	June 30, 2022
	Level 1		Level 2		Level 3		Total
Assets:
Pension plan assets(1)	$	—	$	24,911	$	—	$	24,911
Total assets measured at fair value	$	—	$	24,911	$	—	$	24,911

Liabilities:
Convertible loan derivatives(2)		—		2,297		—		2,297
Debt related Consent Warrants(3)		—		436		—		436
Debt related Consent Shares		15		—		—		15
Total liabilities measured at fair value	$	15	$	2,733	$	—	$	2,748

- 11 -


	March 31, 2022
	Level 1		Level 2		Level 3		Total
Assets:
Pension plan assets(1)	$	—	$	24,778	$	—	$	24,778
Total assets measured at fair value	$	—	$	24,778	$	—	$	24,778

Liabilities:
Convertible loan derivatives(2)		—		11,858		—		11,858
Debt related Consent Warrants(3)		—		1,657		—		1,657
Debt related Consent Shares		77		—		—		77
Total liabilities measured at fair value	$	77	$	13,515	$	—	$	13,592

September 30, 2021

Level 1

Level 2

Level 3

Total

Assets:

Pension plan assets⁽¹⁾

$
—

$
18,870

$
—

$
18,870

Short-term investments⁽²⁾

—

—

—

—

Foreign currency forward contracts⁽³⁾

—

12

—

12

Total assets measured at fair value

$
—

$
18,882

$
—

$
18,882

September 30, 2021

Level 1

Level 2

Level 3

Total

Liabilities:

Convertible loan derivatives⁽⁴⁾

$
—

$
20,632

$
—

$
20,632

Total liabilities measured at fair value

$
—

$
20,632

$
—

$
20,632

(1)

The fair value of pension plan assets has been determined as the surrender value of the portfolio of active insured employees held within the AXA LLP Foundation Suisse Romande collective investment fund.

(2)

The fair value of the Convertible loan derivatives has been determined by utilizing a single factor lattice model using market-based observable inputs such as historical share prices for Quotient Limited, interest rates derived from the U.S. Dollar Swap interest rate curve, credit spread, and implied volatility obtained from third party market price quotations.

(3)

The fair value of the Consent Warrants has been determined by utilizing a Black-Scholes model using market-based observable inputs such as historical share prices for Quotient Limited, quotations for US treasury interest rates, and implied volatility obtained from third party market price quotations.

March 31, 2021

Level 1

Level 2

Level 3

Total

Assets:

Pension plan assets⁽¹⁾

$
—

$
15,751

$
—

$
15,751

Short-term investments⁽²⁾

—

15,000

—

15,000

Foreign currency forward contracts⁽³⁾

—

$
355

—

355

Total assets measured at fair value

$
—

$
31,106

$
—

$
31,106

~~(1)~~

~~(2)~~

The fair value of short-term investments has been determined based on the quoted value of the units held in the money market fund at the balance sheet date. The short-term investments as of March 31, 2021, relate to investments made in a Treasury Money Market Fund. Quotient sold these investments during the quarter ended September 30, 2021

~~(3)~~

The fair value of foreign currency forward contracts has been determined by calculating the present value of future cash flows, estimated using market-based observable inputs including forward and spot exchange rates and interest rate curves obtained from third party market price quotations.

~~(4)~~

On March 12, 2021, the Company announced that 2 funds managed by CSAM in which the Company had invested an aggregate of approximately ~~$110.35~~$110.35 million had suspended redemptions. The investments into these funds were made in accordance with the Company’s investment policy of making individual investments with a minimum of an A rating from a leading credit-rating agency. Each fund holds short-term credit obligations of various obligors. According to a press release issued by CSAM, redemptions in the funds were suspended because ~~“certain~~"certain part of the Subfunds’ assets is currently subject to considerable uncertainties with respect to their accurate valuation.”" CSAM subsequently began a liquidation of the funds. Pursuant to the liquidation, the Company has already received cash distributions of approximately ~~$86.8~~$89.0 million. Of this $86.8 million, the Company received $11.2 million of distributions during the three month period ended September 30, 2021 and $29.7 million during the six month period ended September 30, 2021. Based on information provided by Credit Suisse, the Company expects to receive further cash distributions from the funds in the next several months; however, there can be no assurance as to the timing or amount of any such distributions. Credit Suisse has advised that the credit assets held by the funds are covered by insurance that potentially will be available to cover losses the funds would incur if any of the obligors on the funds’ credit assets were to default.

~~- 13 -~~

On April 22, 2021, Credit Suisse published its FY 2021 Q1 press release with commentary related to the ~~supply chain financing funds.~~Credit Suisse Supply Chain Finance Investment Grade Fund and the Credit Suisse (Lux) Supply Chain Finance Fund. Notably, Credit Suisse indicated that ~~the~~ investors in the funds should assume losses will be incurred. Additionally on April 4, 2022, Credit Suisse indicated in its Annual General Meeting that they expected that litigation will be necessary to reinforce claims against individual debtors and insurance companies and recovery is not expected to occur over the next 12 months for one of our funds. Therefore, we determined that one of our two funds should be classified as long-term as of March 31, 2022 and we have maintained that classification in June 30, 2022.

~~For~~

In the ~~year ended~~year-ended March 31, 2021, Credit Suisse’s decision to liquidate funds in which the Company held ~~short-term~~ investments served as a trigger to evaluate the investments for ~~impairment. Accordingly, we performed a qualitative assessment for impairment. As a result of this assessment, Quotient determined that an~~ impairment ~~was required. The~~and each quarter the Company evaluates information from Credit Suisse ~~linked short-term investment asset with a carrying value of $110.3 million was written down~~ to its estimated fair value of $108.0 million, resulting in an impairment of $2.3 million. This impairment was included in Other, net within our consolidated statements of comprehensive loss for the year endeddetermine whether there are further triggering events. Through March 31, ~~2021. No additional information was received during~~2022, the Company recorded $3.3 million in impairments associated with these funds. We recorded $1.0 million in impairment expenses in the quarter ended ~~September~~June 30, ~~2021 that~~2022 based on information shared by Credit Suisse to CSAM investors on July 18, 2022, which included updated estimates of litigation costs incurred or to be incurred by Credit Suisse which Credit Suisse communicated would ~~indicate further impairments were required. The carrying value of~~be deducted from investor recoveries.

No impairment expense was recorded in the ~~investments at September~~quarter ended June 30, ~~2021 was $20.8 million.~~2021.

The Company views the liquidation of the supply chain finance funds as a fluid situation with a significant amount of valuation uncertainty. The Company will closely monitor the situation and in the event that new information is released that provides valuation clarity, it will evaluate the accounting implications accordingly. The Company believes, and has advised Credit Suisse, that any losses on the supply chain funds, including recovery costs, should be borne by Credit Suisse. The Company will pursue all available options to recoup the full amount of its investment in the supply chain funds prior to liquidation.

The total unrealized gains on the short-term investments were ~~$275~~$258 and ~~$423~~$359 in the ~~six~~three month periods ended ~~September~~June 30, ~~2021~~2022 and ~~September~~June 30, ~~2020,~~2021, respectively. The amount of these unrealized gains reclassified to earnings were ~~$193~~$7 and ~~$906~~$121 in the ~~six~~three month periods ended ~~September~~June 30, 2022 and June 30, 2021, ~~and September 30, 2020,~~ respectively.

Note 7.6. Ordinary and Preference Shares

Ordinary shares

The Company’s issued and outstanding ordinary shares were as follows:


	Shares Issued and Outstanding						Shares Issued and Outstanding
	September 30, 2021		March 31, 2021		Par value		June 30, 2022		March 31, 2022		Par value
Ordinary shares		101,591,632		101,264,412	$	—		135,683,559		102,611,397	$	—
Total		101,591,632		101,264,412	$	—		135,683,559		102,611,397	$	—

During the quarter ended June 30, 2022, the Company issued 32,458,336 ordinary shares in a public offering of shares at $0.30 per share.

Preference shares

The Company’s issued and outstanding preference shares consist of the following:

	Shares Issued and Outstanding				Liquidation amount per share
	September 30, 2021		March 31, 2021		September 30, 2021		March 31, 2021		Shares Issued and Outstanding				Liquidation amount per share
7% Cumulative Redeemable Preference shares		666,665		666,665	$	33.00	$	32.21
									June 30, 2022		March 31, 2022		June 30, 2022		March 31, 2022
7% Cumulative Redeemable Preference shares										666,665		666,665	$	34.18	$	32.21
Total		666,665		666,665						666,665		666,665

The 7%7% Cumulative Redeemable Preference shares were issued to Ortho-Clinical Diagnostics Finco S.A.R.L., an affiliate of Ortho on January 29, 2015 at a subscription price of ~~$22.50~~$22.50 per share. These preference shares are redeemable at the request of the shareholder on the ~~“Redemption~~"Redemption Trigger ~~Date”~~Date" which is currently the date of the ~~eighth~~ninth anniversary of the date of issue of the preference shares, but the Company may further extend the redemption date in one year increments up to the tenth anniversary of the date of issue. Because the 7% Cumulative Redeemable Preference shares are redeemable at the option of the shareholders, they are shown as a liability in the unaudited condensed consolidated balance sheet.

Note 8.7. Share-Based Compensation

The Company records share-based compensation expense in respect of options and restricted share units ~~(“RSUs”~~("RSUs") issued under its share incentive plans. Share-based compensation expense amounted to ~~$1,404~~$1,634 and ~~$1,324~~$1,823 in the quarters ended ~~September~~June 30, 2022 and June 30, 2021, ~~and September 30, 2020, respectively, and $3,227 and $2,284 in the six month periods ended September 30, 2021 and September 30, 2020,~~ respectively.

Share option activity

The following table summarizes share option activity:

	Number of Share Options Outstanding			Weighted Average Exercise Price		Weighted Average Remaining Contractual Life (Months)
Outstanding — March 31, 2021		1,810,785		$	7.69		68
								Number of Share Options Outstanding			Weighted Average Exercise Price		Weighted Average Remaining Contractual Life (Months)
Outstanding — March 31, 2022									2,850,548		$	4.88		90
Granted		1,150,504			3.71	120			572,122			1.41		120
Exercised		(4,677	)		1.44		—		—			—		—
Forfeited		(154,803	)		6.74		—		(394,436	)		7.58		—
Outstanding — September 30, 2021		2,801,809		$	6.12	84
Exercisable —September 30, 2021		1,422,282		$	8.20		55
Outstanding — June 30, 2022									3,028,234		$	3.87		95
Exercisable — June 30, 2022									989,250		$	6.45		61

The closing price of the Company’s ordinary shares on the Nasdaq Global Market at ~~September~~June 30, ~~2021~~2022 was ~~$2.34.~~$0.24.

- 13 -

The following table summarizes the options granted in the ~~six~~three month period ended ~~September~~June 30, ~~2021~~2022 with their exercise prices, the fair value of ordinary shares as of the applicable grant date, and the intrinsic value, if any:

Grant Date

Number of
Options Granted

Exercise Price

Ordinary
Shares
Fair Value Per
Share at Grant
Date

Per Share
Intrinsic
Value of
Options

April 1, 2021 ⁽¹⁾

857,015

$
3.68

$
3.68

$
2.41

June 10, 2021

133,386

4.37

4.37

2.85

August 1, 2021

118,734

3.41

3.41

2.21

August 3, 2021

4,556

3.38

3.38

2.20

September 1, 2021

36,813

3.07

3.07

2.01


Grant Date	Number of Options Granted		Exercise Price		Ordinary Shares Fair Value Per Share at Grant Date		Per Share Intrinsic Value of Options
April 1, 2022		504,882	$	1.20	$	1.20	$	0.79
May 1, 2022		67,240		0.58		0.58		0.39

⁽¹⁾

On April 1, 2021, in connection with the appointment of Manuel O. Méndez as Chief Executive Officer, we granted Mr. Méndez 857,015 options to purchase ordinary shares at an exercise price of $3.68 per share. These grants, which were issued outside of our 2014 Stock Incentive Plan, were approved by our Board of Directors and the Remuneration Committee of our Board pursuant to the inducement grant exception under Nasdaq Rule 5635(c)(4), as an inducement that is material to Mr. Méndez joining our Company. The options vest in three equal installments on each first, second and third anniversary of the grant date. The options have a term of ten years and will be forfeited if not exercised before the expiration of their term. In addition, in the event Mr. Méndez’s service is terminated, any options not vested shall be forfeited upon termination. Subsequent to September 30, 2021, 138,227 of the stock options originally granted to Mr. Méndez were cancelled in connection with an amendment to his employment agreement with the Company

Determining the fair value of share options

The fair value of each grant of share options was determined by the Company using the Black Scholes option pricing model. The total fair value of option awards in the ~~six~~three months ended ~~September~~June 30, 2022 and June 30, 2021 ~~and September 30, 2020~~ amounted to ~~$2,793~~$0.4 and ~~$441,~~$2.4 million, respectively.

Assumptions used in the option pricing models are discussed below. Each of these inputs is subjective and generally requires significant judgment to determine.

~~- 15 -~~

Expected volatility. The expected volatility was based on the historical share price volatility of the Company’s shares over a period equal to the expected terms of the options.

Fair value of ordinary shares. ~~Since the Company’s initial public offering in April 2014, the~~The fair value of ordinary shares ~~has been~~is based on the share price of the Company’s shares on the Nasdaq Global Market immediately prior to the grant of the options concerned.

Risk-Free Interest Rate. The risk-free interest rate is based on the ~~UK Government 10-year bond yield curve in effect at the time of grant prior to the initial public offering and~~ 10-year U.S. Treasury ~~Stock for awards from April 2014 onwards.~~rate at time of grant.

Expected term. The expected term is determined after giving consideration to the contractual terms of the share-based awards, graded vesting schedules ranging from one to three years and expectations of future employee behavior as influenced by changes to the terms of its share-based awards.

Expected dividend. According to the terms of the awards, the exercise price of the options is adjusted to take into account any dividends paid. As a result, dividends are not required as an input to the model, as these reductions in the share price are offset by a corresponding reduction in exercise price.

A summary of the weighted-average assumptions applicable to the share options issued during the ~~six~~three month period ended ~~September~~June 30, ~~2021~~2022 is as follows:


Risk-free interest rate		2.46	%
Expected lives (years)		6
Volatility		73.96	%
Dividend yield		—
Grant date fair value (per share)	$	1.13
Number granted		572,122

Risk-free interest rate

1.64
%
Expected lives (years)

6

Volatility

74.19
%
Dividend yield

—

Grant date fair value (per share)

$
3.83

Number granted

1,150,504

A summary of the RSUs in issue at ~~September~~June 30, ~~2021~~2022 is as follows:

Number
of RSUs
Outstanding

Weighted
Average
Remaining
Vesting Period
(Months)

Period in which the
target must be
achieved
RSUs subject to time based vesting

1,916,314

16

N/A
RSUs subject to milestone and performance based vesting

840,383

N/A

N/A


	Number of RSUs Outstanding
RSUs subject to time based vesting		2,265,195
RSUs subject to milestone and performance based vesting		2,173,500

At ~~September~~June 30, ~~2021, 1,916,314~~2022, 2,265,195 RSUs were subject to time-based vesting and the weighted average remaining vesting period was 1615 months. In addition, ~~91,031~~24,552 RSUs were subject to vesting based on the achievement of various business milestones related mainly to the development, approval and marketing of MosaiQ. ~~749,352~~2,148,948 RSUs were subject to vesting based on the achievement of financial objectives in the year ~~2024. Subsequent~~2024 and 2025 assuming a 100% payout of applicable targets. If the maximum payout ratio of these awards were to ~~September 30, 2021, 181,159~~be achieved of ~~the outstanding RSUs were cancelled in connection with an amendment to the employment agreement between Mr. Méndez and the Company.~~150%, 3,223,422 shares would be awarded.

- 14 -

Note 9.8. Income Taxes

A reconciliation of the income tax expense at the statutory rate to the provision for income taxes is as follows:

	Quarter ended September 30,						Six months ended September 30,
	2021			2020			2021			2020			Quarter ended June 30
													2022			2021
Income tax expense at statutory rate													$	—		$	—
Tax rate change	$	—		$	—		$	335						0			(335	)
Foreign tax rate differential		(1,337	)		(1,013	)		(1,920	)		(1,582	)		746			583
Increase in valuation allowance against deferred tax assets		1,182			862			2,100			1,278			(879	)		(918	)
Provision for income tax	$	(155	)	$	(151	)	$	515		$	(304	)	$	(133	)	$	(670	)

~~- 16 -~~

Note ~~10.~~9. Defined Benefit Pension Plans

The Company’s Swiss subsidiary has a fully insured pension plan managed by AXA LPP Foundation Suisse Romande. The costs of this plan were:

	Quarter ended						Six months ended
	September 30,						September 30,						Quarter ended June 30
	2021			2020			2021			2020			2022			2021
Employer service cost	$	627		$	627		$	1,253		$	1,198		$	706		$	626
Interest cost		23			32			44			62			100			22
Expected return on plan assets		(76	)		(64	)		(153	)		(121	)		(112	)		(76	)
Amortization of prior service credit		14			14			29			27			14			15
Amortization of net loss					—						—			0			0
Net pension cost	$	588		$	609		$	1,173		$	1,166		$	708		$	587

The employer contributions for the ~~six~~three month periods ended ~~September~~June 30, 2022 and 2021 were $485and ~~September 30, 2020 were $819 and $652,~~$398, respectively. The estimated employer contributions for the fiscal year ending March 31, ~~2022~~2023 are ~~$1,436.~~$1,948.

Note ~~11.~~10. Net Loss Per Share

In accordance with Accounting Standards Codification Topic 260 “"Earnings Per ~~Share~~Share"”, basic earnings available to ordinary shareholders per share is computed based on the weighted average number of ordinary shares outstanding during each period. Diluted earnings available to ordinary shareholders per share is computed based on the weighted average number of ordinary shares outstanding during each period, plus potential ordinary shares considered outstanding during the period, as long as the inclusion of such shares is not anti-dilutive. Potential ordinary shares consist of the incremental ordinary shares issuable upon the exercise of share options (using the treasury shares method), the warrants to acquire ordinary shares, the ordinary shares issuable upon vesting of the RSUs, and the ordinary shares issuable on conversion of Convertible Notes.

The following table sets forth the computation of basic and diluted loss per ordinary share:

Quarter ended

Six months ended

September 30,

September 30,

2021

2020

2021

2020

Numerator:

Net loss

$
(27,105
)

$
(13,755
)

$
(54,397
)

$
(40,011
)
Net loss available to ordinary shareholders - basic

(27,105
)

(13,755
)

(54,397
)

(40,011
)
Net loss available to ordinary shareholders - diluted

(33,858
)

(13,755
)

(54,397
)

(40,011
)

Denominator:

Weighted-average shares outstanding - basic

101,567,664

83,949,195

101,479,690

82,227,052

Weighted-average shares outstanding - diluted

120,086,178

83,949,195

101,479,690

82,227,052

Loss per share - basic

$
(0.27
)

$
(0.16
)

$
(0.54
)

$
(0.49
)
Loss per share - diluted

$
(0.28
)

$
(0.16
)

$
(0.54
)

$
(0.49
)


	Quarter ended
	June 30
	2022			2021
Numerator:
Net loss available to ordinary shareholders - basic and diluted	$	(38,868	)	$	(27,292	)
Denominator:
Weighted average ordinary shares outstanding		103,840,009			101,390,749
Assumed exercise of pre-funded warrants		751,831			0
Weighted-average shares outstanding - basic and diluted		104,591,840			101,390,749
Loss per share - basic and diluted	$	(0.37	)	$	(0.27	)

The 34,208,331 pre-funded warrants issued during the quarter ended June 30, 2022, are assumed to be exercised for the calculation of basic and diluted loss per share as the exercise price of $0.001 was deemed to be a non-substantive exercise price compared to the pre-funded cost of $0.299 per share and the fair value of our ordinary shares. These are treated as permanent equity for both basic and

- 1715 -

diluted earnings per share calculations. Pre-funded warrants are not included in shares outstanding in our statement of stockholders equity or balance sheet, however the proceeds have been included in the value of share capital therein.

The following table sets out the numbers of ordinary shares excluded from the above computation of earnings per share at ~~September~~June 30, ~~2021~~2022 and ~~September~~June 30, ~~2020~~2021 as their inclusion would have been anti-dilutive:

September 30,
2021

September 30,
2020

Ordinary shares issuable on conversion of Senior Convertible Notes
at $5.67 per share⁽¹⁾

-

-

Restricted share units awarded

2,756,697

854,422

Ordinary shares issuable on exercise of options to purchase ordinary
shares

2,801,809

1,899,280

Ordinary shares issuable on exercise of warrants at $16.14 per share

111,525

111,525

Ordinary shares issuable on exercise of warrants at $9.375 per share

64,000

64,000

5,734,031

2,929,227


	June 30, 2022		June 30, 2021
Ordinary shares issuable on conversion of Convertible Notes at $5.67 per share		18,518,514		18,518,514
Restricted share units awarded		4,438,695		2,196,595
Ordinary shares issuable on exercise of options to purchase ordinary shares		3,028,234		1,421,792
Ordinary shares issuable on exercise of warrants at $16.14 per share		111,525		111,525
Ordinary shares issuable on exercise of warrants at $9.375 per share		64,000		64,000
Ordinary shares issuable on exercise of Consent Warrants at $4.00 per share		1,844,020		—
Consent Shares not yet issued		64,330		—
Total		28,069,318		22,312,426

⁽¹⁾

~~Ordinary shares issuable on conversion of Senior Convertible Notes at $5.67 per share, representing 18,518,514 shares, are anti-dilutive for the six months ended September 30, 2021.~~

- 1816 -

Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations

You should read the following discussion and analysis of our financial condition and results of operations in conjunction with the corresponding section of our Annual Report on Form ~~10-K/A~~10-K for the year ended March 31, ~~2021~~2022 filed with the SEC on ~~November 15, 2021.~~June 28, 2022.

The information set forth and discussed below for the quarters ended ~~September~~June 30, ~~2021~~2022 and ~~September~~June 30, ~~2020~~2021 is derived from the condensed consolidated financial statements included under Part I, Item 1 ~~“Financial Statements”~~"Financial Statements" above. The financial information set forth and discussed below is unaudited but includes all normal and recurring adjustments that our management considers necessary for a fair presentation of the financial position and the operating results and cash flows for those periods. Our results of operations for a particular quarter may not be indicative of the results that may be expected for other quarters or the entire year.

In addition to historical financial information, the following discussion contains forward looking statements that reflect our plans, estimates, beliefs and expectations that involve risks and uncertainties. Our actual results and the timing of events could differ materially from those discussed in these forward-looking statements. Factors that could cause or contribute to these differences include those discussed below and elsewhere in this Quarterly Report, and our Annual Report on Form ~~10-K/A~~10-K for the year ended March 31, ~~2021,~~2022, particularly in ~~“Risk~~"Risk Factors.”"

Overview

We were incorporated in Jersey, Channel Islands on January 18, 2012. On February 16, 2012, we acquired the entire issued share capital of Alba Bioscience Limited (or Alba), Quotient Biodiagnostics, Inc. (or QBDI) and QBD (QSIP) Limited (or QSIP) from Quotient Biodiagnostics Group Limited (or QBDG), our predecessor.

Our Business

We are a commercial-stage diagnostics company committed to reducing healthcare costs and improving patient care through the provision of innovative tests within established markets. Our initial focus is on blood grouping and donor disease screening, which is commonly referred to as transfusion diagnostics. Blood grouping involves specific procedures performed at donor or patient testing laboratories to characterize blood, which includes antigen typing and antibody detection. Disease screening involves the screening of donor blood for unwanted pathogens using two different methods, a serological approach (testing for specific antigens or antibodies) and a molecular approach (testing for DNA or RNA).

We have over 3530 years of experience developing, manufacturing and commercializing conventional reagent products used for blood grouping within the global transfusion diagnostics market. We are developing MosaiQ, our proprietary technology platform, to better address the comprehensive needs of this large and established market. We believe MosaiQ has the potential to transform transfusion diagnostics, significantly reducing the cost of blood grouping in the donor and patient testing environments, while improving patient outcomes.

We currently operate as one business segment with ~~433~~437 employees in the United Kingdom, Switzerland and the United States, as of ~~September~~June 30, ~~2021.~~2022. Our principal markets are the United States, Europe and Japan. Based on the location of the customer, revenues outside the United States accounted for ~~43%~~45% of total revenue during the ~~six~~three month period ended ~~September~~June 30, ~~2021~~2022 and ~~30%~~44% during the ~~six~~three month period ended ~~September~~June 30, ~~2020.~~2021.

We have incurred net losses and negative cash flows from operations in each year since we commenced operations in 2007. As of ~~September~~June 30, ~~2021,~~2022, we had an accumulated deficit of ~~$654.3~~$763.9 million. We expect our operating losses to continue for at least the remainder of the fiscal year ending March 31, ~~2022~~2023 as we continue our investment in the commercialization of MosaiQ. For the ~~six~~three month period ended ~~September~~June 30, ~~2021,~~2022, our total revenue was ~~$18.6~~$8.8 million and our net loss was ~~$54.4~~$38.9 million.

From our incorporation in 2012 to March 31, ~~2021,~~2022, we have raised $160.0 million of gross proceeds through the private placement of our ordinary and preference shares and warrants, ~~$433~~$433.0 million of gross proceeds from public offerings of our ordinary shares and issuances of ordinary shares upon exercise of warrants, ~~and~~ $145.0 million of gross proceeds from the issuance of 12% Senior Secured Notes ordue 2025 (which we refer to as the ~~“Secured Notes”.~~

~~On May 26, 2021, we issued $95.0~~Secured Notes) and $105 million ~~aggregate principal amount~~ of gross proceeds from the issuance of 4.75% Convertible Notes due 2026 ~~(the “Convertible Notes”) and on June 2, 2021,~~(which we ~~issued an additional $10.0 million aggregate principal amount of~~refer to as the Convertible ~~Notes.~~ Notes). In addition, on March 23, 2018, we raised $20.9 million from the sale and leaseback of our conventional reagents manufacturing facility near Edinburgh, Scotland, which we refer to as the Allan Robb Campus, or ARC, facility.

During the quarter ended June 30, 2022, we raised gross proceeds of approximately $20.0 million from a public offering of 32,458,336 of our ordinary shares and, in lieu of ordinary shares to certain investors, pre-funded warrants exercisable for an aggregate of 34,208,331 ordinary shares at an exercise price of $0.001 per share.

As of ~~September~~June 30, ~~2021,~~2022, we had available cash, cash equivalents and ~~short-term~~ investments of ~~$141.8~~$63.2 million and ~~$8.3~~$8.7 million of restricted cash held as part of the arrangements relating to our Secured Notes and the lease of our property in Eysins, Switzerland.

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Regulatory and Commercial Milestones

You should read the following regulatory and commercial milestones update in conjunction with the discussion included under the sections ~~“Item~~"Item 1. ~~Business”~~Business" and ~~“Item~~"Item 1A. Risk ~~Factors”~~Factors" of our Annual Report on Form ~~10-K/A~~10-K for the year ended March 31, ~~2021~~2022 filed with the SEC on ~~November 15, 2021.~~June 28, 2022.

IH Extended and Patient Microarrays

•

Initial European Regulatory Approval – we filed for European regulatory approval for our initial MosaiQ IH Microarray in late September 2018 and were notified of its approval on April 30, 2019. We also filed for European regulatory approval of the initial MosaiQ SDS Microarray in June 2019 and were notified of its approval on February 14, 2020.

•

Our extended IH microarray launched commercially in the European Union in the first half of 2022 and we currently expect that our MosaiQ patient IH microarray will commercially launch in the European Union before the end of calendar year 2023.

•

Ongoing Microarray Menu Development – our activities for the expansion of our IH and SDS, testing menus included the completion of the validation and verification, or “V&V”, concordance study for the expanded MosaiQ IH Microarray menu, which we announced in October 2019.

•

Field Trials – we commenced field trials for the expanded MosaiQ IH Microarray in Europe in the first quarter of calendar year 2020. These trials were initially suspended due to the COVID-19 pandemic in March 2020, but by the end of May 2020, quarantine and containment measures and restrictions had eased in all three trial locations allowing the work to recommence. However, subsequent governmental restrictions implemented towards the end of 2020 have impacted our ability to conduct these trials, as discussed below. We announced the initial results from these trials in November 2020. Based on our internal performance testing, we subsequently determined to enhance a limited number of the tests on the expanded MosaiQ IH Microarray. In June 2021, we restarted field trials in Europe. The commencement of field trials in the United States for the expanded MosaiQ IH Microarray has also been postponed due to the COVID-19 pandemic. We expect these trials to commence in the fourth quarter of calendar year 2021. We expect EU and U.S. field trials for the expanded MosaiQ SDS Microarray as well as the Plasma Microarray to commence in the second quarter of calendar year 2022.

•

Ongoing Regulatory Approval Process – We submitted the European regulatory dossier for the expanded MosaiQ IH Microarray in November 2021. We continue to expect to receive the CE mark for the expanded MosaiQ IH Microarray around year end. We expect FDA submission in the first quarter of calendar year 2022. The expanded immunohematology microarray will require BLA for US and we therefore expect anticipated timeline of approval between 15-18 months depending on the agency. We expect to make a European regulatory submission for the expanded MosaiQ SDS Microarray in the third quarter of calendar year 2022, with the U.S. regulatory submission following in the third or fourth quarter of calendar year 2022.

•

Patient IH Microarray – we are developing for Ortho-Clinical Diagnostics Inc. (or Ortho), a dedicated MosaiQ IH Microarray optimized for the patient transfusion market (which we refer to as the MosaiQ IH3 Microarray), and we expect to make a European regulatory submission in the second half of calendar year 2022.

~~COVID-19 Pandemic~~

You should read the following COVID-19 pandemic update in conjunction with the discussion included under the sections “Item 1. Business” and “Item 1A. Risk Factors” of our Annual Report on Form 10-K/A for the year ended March 31, 2021 filed with the SEC on November 15, 2021.

On March 11, 2020, the World Health Organization declared the novel strain of coronavirus (COVID-19) a global pandemic and recommended containment and mitigation measures worldwide. The governments of eachWe currently expect commercial launch of the ~~major locations~~extended IH microarray and the patient IH microarray in ~~which we operate,~~ the United ~~Kingdom, Switzerland~~States to occur in calendar year 2024.

SDS and MDS Microarrays

•

We currently expect commercial launch of the extended MosaiQ SDS microarray in European Union to occur before the end of calendar year 2023 in the United States before the end of calendar year 2024.

•

We currently expect commercial launch of the MosaiQ MDS microarray in the European Union to occur before the end of calendar year 2025.

CDS Microarrays

•

We currently expect commercial launch of the CDS autoimmune microarray in the European Union and the United States ~~have implemented varying measures and restrictions~~ to ~~combat the COVID-19 pandemic.~~

The restrictions implemented at the beginning of the pandemic directly impacted our on-going clinical trials for our expanded MosaiQ IH Microarray in Europe and the commencement of clinical trials for our expanded MosaiQ IH Microarray in the United States. All external work on these trials was suspended in March 2020 until such time as the existing restrictions in the relevant jurisdictions are removed or moderated. Byoccur before the end of ~~May 2020, quarantine and containment measures and restrictions had eased in all~~calendar year 2023.

•

We currently expect commercial launch of the ~~three European trial locations allowing the work~~CDS allergy microarray to ~~recommence.~~

~~- 20 -~~

~~In addition, on April 6, 2020, we~~ announced the completion of the development phase of the MosaiQ COVID-19 Microarray, in response to the COVID-19 pandemic. On April 27, 2020, we published the final performance data for the MosaiQ COVID-19 Microarray, achieving 100% sensitivity and 99.8% specificity, and on May 1, 2020, we announced the CE Mark for this Microarray. In addition, in May 2020, we submitted an application to the FDA for an Emergency Use Authorization (EUA) of the MosaiQ COVID-19 Microarrayoccur in the ~~United States, and in September 2020, we announced~~European Union before the ~~EUA had been issued by the FDA for this Microarray. We signed the first commercial contract for the sale~~end of the MosaiQ COVID-19 Microarray in May 2020, and we have subsequently entered into nine additional contracts with customers in Europe and the United States. In addition, we developed an enhanced, semi-quantitative MosaiQ COVID-19 Microarray, which has been CE marked as of January 29, 2021.calendar year 2024.

Revenue

In spite of this widespread increase of COVID-19 infections, the COVID-19 pandemic and the associated restrictions have not had a material adverse impact on our conventional reagent revenues. Customer demand has remained robust since March 31, 2020 and, to date, supply chain disruptions have been minimal. Our manufacturing operations in Edinburgh, Scotland have been adapted to meet social distancing requirements, which impacted our operating costs during the quarter ended September 30, 2021 and 2020.

However, the COVID-19 pandemic has negatively affected the on-going field trials for our expanded MosaiQ IH Microarray, with travel restrictions and lockdowns making it difficult for relevant teams to spend time on-site and resulting in trials repeatedly stopping and restarting. Furthermore, these restrictions and lockdowns have impacted our research and development activities, slowed down the regulatory approval process and delayed the timing of customer tenders. There continue to be surges in various countries or regions resulting in a continuous process of restriction and lockdown relaxations and re-instatement. This continues to be a challenge to realization of all research and development activities including the clinical trial performance evaluations.

The extent to which the COVID-19 pandemic will impact our business, operations and financial results will depend on future developments and numerous evolving factors, which are highly uncertain and difficult to predict.

~~Revenue~~

We generate product sales revenue from the sale of conventional reagent products directly to hospitals, donor collection agencies and independent testing laboratories in the United States, the United Kingdom and to distributors in Europe and the rest of the world, and indirectly through sales to our original equipment manufacturer (or OEM) customers. We recognize revenues in the form of product sales when the goods are shipped. ~~Products sold by standing purchase orders as a percentage of product sales revenue were 67% and 68% for the~~ ~~six month periods ended September~~ ~~30, 2021 and September 30, 2020, respectively.~~ We also provide product development services to our OEM customers. We recognize revenue from these contractual relationships in the form of product development fees, which are included in other revenues.

Our revenue is denominated in multiple currencies. Sales in the United States and to certain of our OEM customers are denominated in U.S. Dollars. Sales in Europe and the rest of the world are denominated primarily in U.S. Dollars, Pounds Sterling or Euros. Our expenses are generally denominated in the currencies in which our operations are located, which are primarily in the United Kingdom, Switzerland and the United States. We operate globally and therefore changes in foreign currency exchange rates may become material to us in the future due to factors beyond our control.

Cost of revenue and operating expenses

Cost of revenue consists of direct labor expenses, including employee benefits, overhead expenses, material costs and freight costs, along with the depreciation of manufacturing equipment and leasehold improvements. Our gross profit represents total revenue less the cost of revenue, gross margin represents gross profit expressed as a percentage of total revenue, and gross margin on product sales represents gross margin excluding other revenues as a percentage of revenues excluding other revenues. We expect our overall cost of revenue to increase in absolute U.S. Dollars as we continue to increase our product sales volumes. However, we also believe that we can achieve efficiencies in our manufacturing operations, primarily through increasing production volumes.

Our sales and marketing expenses include costs associated with our sales organization for conventional reagent products, including our direct sales force, as well as our marketing and customer service personnel and the costs of the MosaiQ commercial team. These expenses consist principally of salaries, commissions, bonuses and employee benefits, as well as travel and other costs related to our sales and product marketing activities. We expense all sales and marketing costs as incurred. We expect sales and marketing expense to increase in absolute U.S. Dollars, primarily as a result of commissions on increased product sales in the United States and as we grow the MosaiQ commercial team.

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Our research and development expenses include costs associated with performing research, development, field trials and our regulatory activities, as well as production costs incurred in advance of the commercial launch of MosaiQ. Research and development expenses include research personnel-related expenses, fees for contractual and consulting services, travel costs, laboratory supplies and depreciation of laboratory equipment.

We expense all research and development costs as incurred, net of government grants received and tax credits. Our UK subsidiary claims certain tax credits on its research and development expenditures and these are included as an offset to our research and development expenses. Our research and development efforts are focused on developing new products and technologies for the global transfusion diagnostics market. We segregate research and development expenses for the MosaiQ project from expenses for other research and development projects. We do not maintain detailed records of these other costs by activity. We are nearing completion of the initial development of MosaiQ and expect our costs associated with field trials and regulatory approvals will increase at the same time as our development costs with MosaiQ decrease. As we move to commercialization of MosaiQ in the donor testing market, we expect our overall research and development expense to decrease.

Our general and administrative expenses include costs for our executive, accounting and finance, legal, corporate development, information technology and human resources functions. We expense all general and administrative expenses as incurred. These expenses consist principally of salaries, bonuses and employee benefits for the personnel performing these functions, including travel costs. These expenses also include share-based compensation, professional service fees (such as audit, tax and legal fees), costs related to our Board of Directors, and general corporate overhead costs, which include depreciation and amortization. We expect our general and administrative expenses to increase as our business develops and also due to the costs of operating as a public company, such as additional legal, accounting and corporate governance expenses, including expenses related to compliance with the Sarbanes-Oxley Act, directors’ and officers’ insurance premiums and investor relations expenses.

Net interest expense consists primarily of interest charges on our Secured Notes and Convertible Notes and the amortization debt discount and debt issuance costs (which includes amortization of the one-time consent payment of $3.9 million paid to holders of our Secured Notes in December 2018), as well as accrued dividends on the 7% cumulative redeemable preference shares issued in January 2015. We amortize debt issuance costs over the life of the instrument and report them as interest expense in our statements of operations. Net interest also includes the expected costs of the royalty rights agreements we entered into in October 2016, June 2018, December 2018 and May 2019 with the purchasers and consenting holders, as applicable, of our Secured Notes. See Note 3, ~~“Debt”~~"Debt" and Note ~~7, “Ordinary~~6, "Ordinary and Preference ~~Shares”~~Shares" to our condensed consolidated financial statements included in this Quarterly Report for additional information.

Other income (expense), net consists of the change in fair value of our convertible debt derivative, warrant liabilities and the impact of exchange rate fluctuations. See Note 3, ~~“Debt”~~"Debt" and Note ~~6, “Fair~~5, "Fair value ~~measurement”~~measurement" to our condensed consolidated financial statements included in this Quarterly Report for additional information. Exchange rate fluctuations include realized exchange fluctuations resulting from the settlement of transactions in currencies other than the functional currencies of our businesses. Monetary assets and liabilities that are denominated in foreign currencies are measured at the period-end closing rate with resulting unrealized exchange fluctuations. The functional currencies of our legal entities are Pounds Sterling, Swiss Francs, Euros, and U.S. Dollars depending on the entity.

Provision for income taxes in the ~~six~~three month periods ended ~~September~~June 30, ~~2021~~2022 and ~~2020,~~2021, reflected the taxes chargeable on the taxable income of our subsidiaries.

- 2219 -

Results of Operations

Comparison of the Quarters ended ~~September~~June 30, ~~2021~~2022 and ~~2020~~2021

The following table sets forth, for the periods indicated, the amounts of certain components of our statements of operations and the percentage of total revenue represented by these items, showing period-to-period changes.


	Quarter ended September 30,																		Quarter Ended June 30,
	2021						2020						Change						2022						2021						Change
	Amount			% of revenue			Amount			% of revenue			Amount			%			Amount			% of revenue			Amount			% of revenue			Amount			%
	(in thousands, except percentages)																		(in thousands, except percentages)
Revenue:
Product sales	$	9,284			98	%	$	8,543			53	%	$	741			9	%	$	8,814			100	%	$	9,041			99	%	$	(227	)		-3	%
Other revenues		183			2	%		7,523			47	%		(7,340	)		-98	%		—			0	%		48			1	%		(48	)		-100	%
Total revenue		9,467			100	%		16,066			100	%		(6,599	)		-41	%		8,814			100	%		9,089			100	%		(275	)		-3	%
Cost of revenue		4,875			51	%		4,499			28	%		376			8	%		6,120			69	%		4,777			53	%		1,343			28	%
Gross profit		4,592			49	%		11,567			72	%		(6,975	)		-60	%		2,694			31	%		4,312			47	%		(1,618	)		-38	%
Operating expenses:
Sales and marketing		2,640			28	%		2,231			14	%		409			18	%		3,306			38	%		2,493			27	%		813			33	%
Research and development		15,754			166	%		12,743			79	%		3,010			24	%		14,146			160	%		13,531			149	%		615			5	%
General and administrative		10,022			106	%		9,556			59	%		466			5	%		11,037			125	%		10,176			112	%		861			8	%
Total operating expenses		28,416			300	%		24,530			153	%		3,886			16	%		28,489			323	%		26,200			288	%		2,289			9	%
Operating loss		(23,824	)		-252	%		(12,963	)		-81	%		(10,861	)		84	%		(25,795	)		-293	%		(21,888	)		-241	%		(3,907	)		18	%
Other (expense) income:
Interest expense, net		(9,352	)		-99	%		(6,297	)		-39	%		(3,055	)		49	%		(8,574	)		-97	%		(3,002	)		-33	%		(5,572	)		186	%
Other, net		5,916			62	%		5,354			33	%		562			10	%		(4,366	)		-50	%		(1,732	)		-19	%		(2,634	)		152	%
Total other expense, net		(3,436	)		-36	%		(943	)		-6	%		(2,493	)		264	%		(12,940	)		-147	%		(4,734	)		-52	%		(8,206	)		173	%
Loss before income taxes		(27,260	)		-288	%		(13,906	)		-87	%		(13,354	)		96	%		(38,735	)		-439	%		(26,622	)		-293	%		(12,113	)		46	%
Provision for income taxes		155			—			151			—			4			3	%		(133	)		—			(670	)		—			537			-80	%
Net loss	$	(27,105	)		-286	%	$	(13,755	)		-86	%	$	(13,350	)		97	%	$	(38,868	)		-441	%	$	(27,292	)		-300	%	$	(11,576	)		42	%

Revenue

Total revenue for the quarter ended ~~September~~June 30, ~~2021~~2022 decreased by ~~41%~~3% to ~~$9.5~~$8.8 million compared with ~~$16.1~~$9.1 million for the quarter ended ~~September~~June 30, ~~2020. Product sales for the quarter ended September 30, 2021 increased by 9% to $9.3 million, compared with $8.5 million for the quarter ended September 30, 2020.~~2021. The ~~increase~~decrease in product sales ~~was attributable~~relates primarily to ~~growth in incremental direct sales of conventional reagent products to~~reduced orders from an OEM customer ~~and to direct customer~~ in ~~the United States.~~our conventional reagent business. Other revenues for the quarter ended ~~September~~June 30, 2021 related to a small development project for an OEM customer. ~~In the quarter ended September 30, 2020, other revenues~~

~~arose from the recognition~~Cost of ~~an initial milestone payment~~revenue and gross margin

Cost of ~~$7.5 million received from Ortho in respect of the development of the MosaiQ IH3 Microarray.~~

~~Products sold~~revenue increased by ~~standing purchase order were 67% of product sales for the quarter ended September 30, 2021, compared with 67% for the quarter ended September 30, 2020.~~

~~The table below sets forth revenue by product group:~~

Quarter ended September 30,

2021

2020

Change

Amount

% of revenue

Amount

% of revenue

Amount

%

(in thousands, except percentages)

Revenue:

Product sales - OEM customers

$
5,969

63
%

$
5,034

31
%

$
935

19
%
Product sales - direct customers and distributors

$
3,279

35
%

2,942

18
%

337

11
%
Product sales - MosaiQ

36

0
%

567

4
%

(531
)

-94
%
Other revenues

183

2
%

7,523

47
%

(7,340
)

-98
%
Total revenue

$
9,467

100
%

$
16,066

100
%

$
(6,599
)

-41
%

~~OEM Sales.~~ ~~Product sales~~28% to ~~OEM customers increased 19% to $6.0~~$6.1 million for the quarter ended ~~September~~June 30, ~~2021,~~2022 compared with ~~$5.0~~$4.8 million for the quarter ended ~~September~~June 30, ~~2020.~~2021. The increase in costs was ~~attributable~~driven by $0.2 million of write-downs of certain raw materials and work in process inventory associated with MosaiQ to ~~growth~~net realizable value. There were also higher costs in ~~incremental sales of~~our conventional reagent ~~products.~~

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~~Direct Sales to Customers and Distributors.~~ Product sales directly to customers and distributors of $3.3 million for the quarter ended September 30, 2021 increased by $0.3 million compared with $2.9 million for the quarter ended September 30, 2020. This increase wasbusiness due to ~~increased direct~~inventory write-downs and write-offs of certain products due to expiration of products and quality control tests, higher production costs associated with inflation, and higher costs associated with sales ~~in the United States which increased to $3.0 million~~mix in the quarter ended ~~September~~June 30, ~~2021 from $2.7 million in the quarter ended September 30, 2020 as a result of growth in sales to existing customers and expansion of our customer base.~~2022.

~~MosaiQ Product Sales.~~ MosaiQ sales in the quarters ended September 30, 2021 and September 30, 2020 consisted of revenues from our MosaiQ COVID-19 Microarray which decreased due to change in demand related to the COVID-19 pandemic.

~~Other Revenues. Other revenues in the quarter ended September 30, 2021 related to a development project for an OEM customer. In the quarter ended September 30, 2020, other revenues~~ ~~arose from the recognition of an initial milestone payment of $7.5 million received from Ortho in respect of the development of the MosaiQ IH3 Microarray.~~

~~Cost of revenue and gross margin~~

Cost of revenue increased by 8% to $4.9 million for the quarter ended September 30, 2021 compared with $4.5 million for the quarter ended September 30, 2020. The increase was mainly attributable to incremental costs associated with greater sales volumes.

Gross profit on total revenue for the quarter ended ~~September~~June 30, ~~2021~~2022 was ~~$4.6~~$2.7 million, a decrease of ~~60%~~38% when compared with ~~$11.6~~$4.3 million for the quarter ended ~~September~~June 30, ~~2020. The decrease~~2021. Total gross profit on sales was ~~mainly attributable to decrease in other revenues~~31% in the quarter ended June 30, 2022 compared to 47% in the quarter ended June 30, 2021.

Sales and ~~the change in cost of sales described above.~~marketing expenses

~~Gross profit on product sales, which excludes other revenues, was $4.4~~Sales and marketing expenses were $3.3 million for the quarter ended ~~September~~June 30, ~~2021, an increase of 10% when~~2022, compared with ~~$4.0~~$2.5 million for the quarter ended ~~September~~June 30, ~~2020. This increase was mainly attributable to an increase in sales volumes and increased sales in the United States.~~

~~Gross margin on product sales, which excludes other revenues, was 47% for the quarter ended September 30, 2021 and 2020.~~

~~Sales and marketing expenses~~

~~Sales and marketing expenses were $2.6 million for the quarter ended September 30, 2021, compared with $2.2 million for the quarter ended September 30, 2020.~~ 2021. This increase was attributable to greater personnel and other expenses related to the planned commercial launch of MosaiQ and in travel related ~~costs~~.costs. As a percentage of total revenue, sales and marketing expenses were ~~28%~~38% for the quarter ended ~~September~~June 30, ~~2021~~2022 compared to ~~14%~~27% for the quarter ended ~~September~~June 30, ~~2020.~~2021.

Research and development expenses

Research and development expenses increased by ~~24%~~5% to ~~$15.8~~$ 14.1 million for the quarter ended ~~September~~June 30, ~~2021~~2022 compared with ~~$12.7~~$13.5 million for the quarter ended ~~September~~June 30, ~~2020. During the quarter ended September 30, 2021, the~~2021. The increase in research and development ~~costs~~expenses is driven by ~~higher material expenditures associated with the development of MosaiQ, salary~~additional employee and ~~benefit costs,~~third party expenses to support upcoming field trials and ~~provisions on certain raw materials.~~product development.

General and administrative expenses

General and administrative expenses increased by 5%8% to ~~$10.0~~$11.0 million for the quarter ended ~~September~~June 30, ~~2021,~~2022, compared with ~~$9.6~~$10.2 million for the quarter ended ~~September~~June 30, ~~2020.~~2021. This increase was primarily attributable to ~~additional costs, including stock compensation charges, associated with changes in company management offset by lower legal and professional expenses.~~fees incurred to refinance our debt which was

- 20 -

completed on July 6, 2022. We recognized ~~$1.4~~$1.6 million of stock compensation expense in the quarter ended ~~September~~June 30, ~~2021~~2022 compared with ~~$1.3~~$1.8 million in the quarter ended ~~September~~June 30, ~~2020.~~2021. As a percentage of total revenue, general and administrative expenses were ~~106%~~125% for the quarter ended ~~September~~June 30, ~~2021~~2022 compared to ~~59%~~112% for the quarter ended ~~September~~June 30, ~~2020.~~2021.

Other (expense) income

~~- 24 -~~

Net interest expense was ~~$9.4~~$8.6 million for the quarter ended ~~September~~June 30, ~~2021~~2022 compared with ~~$6.3~~$3.0 million for the quarter ended ~~September~~June 30, ~~2020.~~2021. Interest expense in the quarter ended ~~September~~June 30, ~~2021~~2022 included ~~$6.7~~$5.7 million of interest charges on our Secured Notes and royalty liabilities compared with ~~$6.2~~$1.9 million for the quarter ended ~~September~~June 30, ~~2020. T~~he2021. The lower expense recognized in the prior year was a result in a significant change in the royalty cost estimates while no significant changes to estimates occurred in the quarter ended ~~September~~June 30, ~~2021.~~ 2022. Interest expense for the quarter ended ~~September~~June 30, ~~2021~~2022 also included ~~$2.5~~$2.6 million of interest charges related to the Convertible Notes ~~which were issued during~~compared to $0.9 million for the ~~three months~~quarter ended June 30, 2021. The Convertible Notes were issued in the quarter ended June 30, 2021 which is why there is a significant increase in expense in the current year. Net interest expense also included $0.3 million of dividends accrued on the 7% cumulative redeemable preference shares in each of the quarters ended ~~September~~June 30, ~~2021~~2022 and ~~September~~June 30, ~~2020.~~2021. In addition, in the quarter ended ~~September~~June 30, 2021 we realized gains of $0.1 million on our short-term money market investments ~~compared to $0.2~~while no gains were recognized in June 30, 2022.

Other, net was $4.4 million expense for the quarter ended ~~September~~June 30, ~~2020.~~

~~Other, net was $5.9~~2022 compared with $1.7 million in ~~income~~expense for the quarter ended ~~September~~June 30, ~~2021 compared with $5.4 million in income for the quarter ended September 30, 2020.~~2021. For the quarter ended ~~September~~June 30, ~~2021~~2022 this comprised a ~~$9.3~~$10.8 million gain related to the change in fair value associated with derivative liabilities, a $1.0 million impairment related to the ~~Convertible Loan derivatives~~change in estimated fair value of CSAM funds and ~~$3.4~~$14.2 million in foreign exchange losses arising on monetary assets and liabilities denominated in foreign ~~currencies compared~~currencies. In the quarter ended June 30, 2021 we recorded 2.0 million of expense related to ~~$5.4~~the change in fair value associated with the Convertible loan derivative and $0.3 million ofin foreign exchange gains ~~for the quarter ended September 30, 2020.~~arising on monetary assets and liabilities denominated in foreign currencies.

Provision for income taxes

Provision for income taxes in the quarter ended ~~September~~June 30, ~~2021~~2022 and ~~2020,~~2021, reflected the taxes chargeable on the taxable income of our subsidiaries.

~~Comparison of the Six Month Periods ended September 30, 2021 and 2020~~

Six months ended September 30

2021

2020

Change

Amount

% of revenue

Amount

% of revenue

Amount

%

(in thousands, except percentages)

Revenue:

Product sales

$
18,325

99
%

$
17,467

70
%

$
858

5
%
Other revenues

231

1
%

7,523

30
%

(7,292
)

-97
%
Total revenue

18,556

100
%

24,990

100
%

(6,434
)

-26
%
Cost of revenue

9,652

52
%

9,913

40
%

(261
)

-3
%
Gross profit

8,904

48
%

15,077

60
%

(6,173
)

-41
%
Operating expenses:

Sales and marketing

5,133

28
%

4,474

18
%

659

15
%
Research and development

29,285

158
%

24,158

97
%

5,127

21
%
General and administrative

20,198

109
%

19,094

76
%

1,104

6
%
Total operating expenses

54,616

294
%

47,726

191
%

6,890

14
%
Operating (loss)

(45,712
)

-246
%

(32,649
)

-131
%

(13,063
)

40
%
Other income (expense):

Interest expense, net

(12,354
)

-67
%

(13,228
)

-53
%

874

-7
%
Other, net

4,184

23
%

5,562

22
%

(1,378
)

-25
%
Total other expense, net

(8,170
)

-44
%

(7,666
)

-31
%

(504
)

7
%
Loss before income taxes

(53,882
)

-290
%

(40,315
)

-161
%

(13,567
)

34
%
Provision for income taxes

(515
)

-3
%

304

—

(819
)

-269
%
Net loss

$
(54,397
)

-293
%

$
(40,011
)

-160
%

$
(14,386
)

36
%

~~- 25 -~~

~~Revenue~~

Total revenue for the six month period ended September 30, 2021 decreased by 26% to $18.6 million, compared with $25.0 million for the six month period ended September 30, 2020. Product sales increased by 5% while other revenue decreased by 97%. These changes are further explained below. Products sold by standing purchase order were 67% of product sales for the six month period ended September 30, 2021, compared with 68% for the six month period ended September 30, 2020.

~~The table below sets forth revenue by product group:~~

Six months ended September 30

2021

2020

Change

Amount

% of revenue

Amount

% of revenue

Amount

%

(in thousands, except percentages)

Revenue:

Product sales - OEM customers

$
11,825

64
%

$
11,218

45
%

$
607

5
%
Product sales - direct customers
and distributors

6,424

35
%

5,571

22
%

853

15
%
Product sales - MosaiQ

76

0
%

678

3
%

(602
)

-89
%
Other revenues

231

1
%

7,523

30
%

(7,292
)

-97
%
Total revenue

$
18,556

100
%

$
24,990

100
%

$
(6,434
)

-26
%

~~OEM Sales.~~ Product sales to OEM customers increased 5% to $11.8 million for the six month period ended September 30, 2021, compared with $11.2 million for the six month period ended September 30, 2020. The increase was attributable to growth in incremental sales of conventional reagent products.

~~Direct Sales to Customers and Distributors.~~ Product sales directly to customers and distributors of $6.4 million for the six month period ended September 30, 2021 increased by $0.9 million compared with $5.6 million for the six month period ended September 30, 2020. This increase was due to increased direct sales in the United States which increased to $5.8 million in the six month period ended September 30, 2021 from $5.0 million in the six month period ended September 30, 2020 as a result of higher sales to existing customers and the expansion of our customer base.

~~MosaiQ Product Sales.~~ MosaiQ sales in the six months ended September 30, 2021 and September 30, 2020 consisted of revenues from our MosaiQ COVID-19 Microarray which decreased due to change in demand related to the COVID-19 pandemic.

~~Other Revenues~~. Other revenues for the six month period ended September 30, 2021 related to a development project for an OEM customer. In the six month period ended September 30, 2020, other revenues arose from the recognition of an initial milestone payment of $7.5 million received from Ortho in respect of the development of the MosaiQ IH3 Microarray.

~~Cost of revenue and gross margin~~

Cost of revenue decreased by 3% to $9.7 million for the six month period ended September 30, 2021, compared with $9.9 million for the six month period ended September 30, 2020. The decrease in cost of revenue reflected reduced costs associated with operating social distancing restrictions and the incremental costs associated with the 5% increase in product sales in the six month period ended September 30, 2021.

Gross profit on total revenue for the six month period ended September 30, 2021 was $8.9 million, compared with $15.1 million for the six month period ended September 30, 2020. The decrease was attributable to the decrease of $7.3 million of other revenues in the six month period ended September 30, 2021 and offset by the increase in gross margin on product sales described below.

Gross profit on product sales, which excludes other revenues, was $8.7 million for the six month period ended September 30, 2021 compared with $7.6 million for the six month period ended September 30, 2020. This increase was primarily due to increased sales to the United States and lower costs associated with social distancing requirements.

~~Gross margin on product sales, which excludes other revenues, was 47% for the six month period ended September 30, 2021 compared with 43% for the six month period ended September 30, 2020~~.

~~Sales and marketing expenses~~

~~Sales and marketing expenses were $5.1 million for the six month period ended September 30, 2021, compared with $4.5 million for the six month period ended September 30, 2020.~~ ~~This increase was attributable to greater personnel and other expenses related to the~~

~~- 26 -~~

~~planned commercial launch of MosaiQ and in related travel costs. As a percentage of total revenue, sales and marketing expenses were 28% for the six month period ended September 30, 2021 compared to 18% for the six month period ended September 30, 2020.~~

~~Research and development expenses~~

Research and development expenses increased by 21% to $29.3 million for the six month period ended September 30, 2021, compared with $24.2 million for the six month period ended September 30, 2020. Our research and development expenses included expenses of $1.5 million in the six month periods ended September 30, 2021 compared to $1.0 million in September 30, 2020 related to the costs of our intellectual property license with TTP. The increase in research and development costs is driven by higher material expenditures associated with the development of MosaiQ, salary and benefit costs, provisions on certain raw materials and the impact of foreign exchange on costs incurred in the United Kingdom and Switzerland.

~~General and administrative expenses~~

General and administrative expenses increased by 6% to $20.2 million for the six month period ended September 30, 2021, compared with $19.1 million for the six month period ended September 30, 2020, reflecting higher salary and benefit costs and the impact of foreign exchange on costs incurred in the United Kingdom and Switzerland, offset by lower legal expenses related to our now settled dispute with Ortho. We recognized $3.2 million of stock compensation expense in the six month period ended September 30, 2021 compared with $2.3 million in the six month period ended September 30, 2020. As a percentage of total revenue, general and administrative expenses were 109% for the six month period ended September 30, 2021 and 76% for the six month period ended September 30, 2020.

~~Other income (expense)~~

Net interest expense was $12.4 million for the six month period ended September 30, 2021, compared with $13.2 million for the six month period ended September 30, 2020. Interest expense in the six month period ended September 30, 2021 included $8.6 million of interest charges on our Secured Notes and royalty liabilities compared with $13.5 million in the six month period ended September 30, 2020. The decreased expense reflected changes in the royalty cost estimates. Interest expense for the six month period ended September 30, 2021 also included $3.4 million of interest charges related to the Convertible Notes which were issued during the six month period ended September 30, 2021. Net interest expense also included $0.5 million of dividends accrued on the 7% cumulative redeemable preference shares in each of the six month periods ended September 30, 2021 and September 30, 2020. In addition, in the six month period ended September 30, 2021 we realized interest income of $0.1 million on our short-term money market investments compared with $0.8 million for the six month period ended September 30, 2020.

Other, net was $4.2 million in income for the six month period ended September 30, 2021 compared with $5.6 million in income for six month period ended September 30, 2020. For the six month period ended September 30, 2021 this comprised a $7.3 million gain related to the change in fair value associated with the Convertible Loan derivatives and $3.1 million of foreign exchange losses arising on monetary assets and liabilities denominated in foreign currencies compared to $5.6 million of foreign exchange gains for the six month period ended September 30, 2020.

~~Provision for income taxes~~

~~Provision for income taxes in the six month period ended September 30, 2021 reflected the taxes payable on the taxable income of our subsidiaries.~~

Quarterly Results of Operations

Our quarterly product sales can fluctuate depending upon the shipment cycles for our red blood cell-based products, which account for approximately two-thirds of our current product sales. For these products, we typically experience 13 shipping cycles per year. This equates to three shipments of each product per quarter, except for one quarter per year when four shipments occur. Not all products ship on the same day so quarters where four shipments occur do not always align. In fiscal ~~2021~~2022 we ~~made 14 shipments with the~~experienced additional shipments in the ~~first~~third and fourth quarters. In fiscal ~~2022,~~2023, the greatest impact of extra product shipments is expected to occur in our ~~fourth~~third quarter. The timing of shipment of bulk antisera products to our OEM customers may also move revenues from quarter to quarter. We also experience some seasonality in demand around holiday periods in both Europe and the United States. As a result of these factors, we expect to continue to see seasonality and quarter-to-quarter variations in our product sales.

The timing of product development fees included in other revenues is mostly dependent upon the achievement of pre-negotiated project milestones.

~~- 27 -~~

Liquidity and Capital Resources

Since our commencement of operations in 2007, we have incurred net losses and negative cash flows from operations. As of ~~September~~June 30, ~~2021,~~2022, we had an accumulated deficit of ~~$654.3~~$763.9 million. During the ~~six~~three month period ended ~~September~~June 30, ~~2021,~~2022, we incurred a net loss of ~~$54.4~~$38.9 million and used ~~$58.7~~$35.5 million of cash in operating activities. As described under results of operations, our use of cash during the ~~six~~three month period ended ~~September~~June 30, ~~2021~~2022 was primarily attributable to our investment in the development of MosaiQ and corporate costs, including costs related to being a public company.

From our incorporation in 2012 to March 31, ~~2021,~~2022, we have raised $160.0 million of gross proceeds through the private placement of our ordinary and preference shares and warrants, $433.0 million of gross proceeds from public offerings of our ordinary shares and issuances of ordinary shares upon exercise of warrants, ~~and~~ $145.0 million of gross proceeds from the issuance of the Secured ~~Notes.~~

~~On May 26, 2021, we issued~~Notes and ~~sold $95.0~~$105 million ~~aggregate principal amount~~ of gross proceeds from the ~~Convertible Notes to in a private offering to institutional investors and on June 2, 2021, we issued an additional $10.0 million aggregate principal amount~~issuance of the Convertible Notes. ~~The Convertible Notes are guaranteed by our material subsidiaries. The Convertible Notes are our unsecured, senior obligations~~In addition, on March 23, 2018, we raised $20.9 million from the sale and ~~rank equally in right~~leaseback of ~~payment with all~~the Allan Robb Campus.

During the quarter ended June 30, 2022, we raised gross proceeds of approximately $20.0 million from a public offering of 32,458,336 of our ~~existing~~ordinary shares and, ~~future unsecured, unsubordinated indebtedness. The Convertible Notes are convertible at the option~~in lieu of ~~the holders~~ordinary shares to certain investors, pre-funded warrants exercisable for an aggregate of 34,208,331 ordinary shares at an ~~initial conversion rate~~exercise price of ~~176.3668 ordinary shares~~$0.001 per ~~$1,000.00 principal amount of Convertible Notes, subject~~share.

On July 6, 2022, the Company completed the Sixth Supplemental Indenture to ~~customary anti-dilution adjustments. We have the right to redeem the Convertible Notes in certain circumstances.~~

~~Subsequent to September 30, 2021, we amended the Indentures governing our Secured Notes to, among other things, extend the final maturity of~~ the Secured Notes which includes a change to ~~October 2025 and revise~~ the ~~principal~~ amortization payment schedule of the Secured Notes from requiring semi-annual payments ranging from $12.1 million to ~~defer approximately $60~~$24.2 million beginning in April 2023, to requiring quarterly payments of $2.5 million beginning on July 15, 2024 and ending on July 15, 2025, with the remaining principal balance due on October 15, 2025, which will reduce expected amortization payments ~~previously required~~by $93.0 million over the next 36 months prior to ~~be made between April 2021~~the payment of the remaining principal balance at maturity. It eliminates the requirement that

- 21 -

we maintain a cash reserve account for the benefit of holders of the Secured Notes, and ~~April 2023.~~adds a covenant that we maintain a minimum liquidity of at least $8.0 million, comprised of cash and certain other eligible investments, as of the end of each fiscal quarter. See Note 3 ~~“Debt”~~to the financial statements for additional information.

We expect to fund our operations in the near-term, including the ongoing development of MosaiQ through successful field trial completion, achievement of required regulatory authorizations and commercialization from a combination of funding sources. These expected funding sources include the use of existing available cash and investment balances, the sale of rights and other assets, and the issuance of new equity or debt.

~~On March 12, 2021, we announced that two funds managed by CSAM in which~~As of June 30, 2022, we had ~~invested an aggregate~~available cash, cash equivalents and short-term investments of ~~approximately $110.35~~$63.2 million ~~had suspended redemptions. The investments into these funds were made in accordance with our investment policy~~and $8.7 million of making individual investments with a minimum of an A rating from a leading credit-rating agency. Each fund holds short-term credit obligations of various obligors. According to a press release issued by CSAM, redemptions in the funds were suspended because “certainrestricted cash held as part of the ~~Subfunds’~~arrangements relating to our Secured Notes and the lease of our property in Eysins, Switzerland.

Cash Flows for the quarter ended June 30, 2022 and 2021

Operating activities

Net cash used in operating activities was $35.5 million during the three month period ended June 30, 2022, which included net losses of $38.9 million offset by non-cash items of $16.1 million. Non-cash items were depreciation and amortization expense of $1.5 million, share-based compensation expense of $1.6 million, an decrease from the change in fair value of loan derivatives of $10.8 million, Swiss pension costs of $0.2 million, amortization of debt discounts and unrealized foreign currency loss on debt of $21.8 million, impairment of investments of $1.0 million, accrued preference share dividends of $0.3 million, deferred lease rentals of $0.4 million and income taxes of $0.1 million. We also experienced a net cash outflow of $12.8 million from changes in operating assets ~~is currently subject~~and liabilities during the period, consisting of a $1.5 million decrease in accrued compensation and benefits, a $1.1 million increase in inventories, a decrease of $10.1 million from a net change in other assets and liabilities, a $0.9 million reduction in accounts payable and accrued liabilities, and a $0.8 million decrease in accounts receivables.

Net cash used in operating activities was $32.1 million during the three month period ended June 30, 2021, which included net losses of $27.3 million offset by non-cash items of $5.2 million. Non-cash items were depreciation and amortization expense of $1.9 million, share-based compensation expense of $1.8 million, change in fair value of convertible loan derivatives of $2.0 million, Swiss pension costs of $0.2 million, a credit related to ~~considerable uncertainties with respect~~amortization of deferred debt issue costs and royalties of $1.6 million, accrued preference share dividends of $0.3 million, deferred lease rentals of $0.2 million and a credit to ~~their accurate valuation.”~~deferred income taxes of $0.4 million. We also experienced a net cash outflow of $10.0 million from changes in operating assets and liabilities during the period, consisting of a $4.2 million reduction in accrued compensation and benefits, a $0.8 million increase in inventories, a $3.5 million increase in other assets and a $2.4 million reduction in accounts payable and accrued liabilities, offset by a $0.9 million reduction in accounts receivables.

Investing activities

Net cash (used in) provided by investing activities was $0.8 million for the quarter ended June 30, 2022 compared to $12.6 million for the quarter ended June 30, 2021.

We spent $0.8 million on purchases of property and equipment in the quarter ended June 30, 2022 compared to $1.4 million in the quarter ended June 30, 2021. Property and equipment purchased in both quarters mainly related to MosaiQ instruments and investments in our IT infrastructure. In the quarter ended June 30, 2021, we also received distributions on our short-term money market investments of $18.5 million from CSAM ~~subsequently began a liquidation~~in the quarter and invested $4.5 million in other short-term money market investments.

Financing activities

Net cash provided by financing activities was $17.7 million during the quarter ending June 30, 2022, consisting of $17.9 million of proceeds related to the issuance of ordinary shares and warrants after deducting issuance costs and $0.2 million of repayments on finance leases.

Net cash provided by (used in) financing activities was $88.1 million during the quarter ended June 30, 2021, consisting of $100.5 million generated from the issuance of the ~~funds. Pursuant~~Convertible Notes, net of debt issue costs, offset by $12.1 million repayment of the Secured Notes, expenses related to ~~the liquidation,~~restricted stock units vested of $0.1 million and $0.2 million of repayments on finance leases.

Operating and Capital Expenditure Requirements

We have not achieved profitability on an annual basis since we ~~have already received cash distributions of approximately $86.8 million. Based on information provided by Credit Suisse,~~commenced operations in 2007 and we expect our operating losses to ~~receive further cash distributions from~~continue for at least the ~~funds~~remainder of the fiscal year ending March 31, 2023. As we launch MosaiQ in the ~~next several months; however, there can~~donor testing market, we expect our operating expenses during the year ended March 31, 2023 to be ~~no assurance~~similar to those of the year ended March 31, 2022.

As of June 30, 2022, we had $63.2 million of available cash, cash equivalents, and investments and $8.7 million of restricted cash held as part of the arrangements relating to our Secured Notes and the ~~amount or~~lease of our properties in Eysins, Switzerland.

- 22 -

Our future capital requirements will depend on many factors, including:

•

our progress in developing and commercializing MosaiQ and the cost required to complete development, obtain regulatory approvals and complete our manufacturing scale up;

•

our ability to pursue successful alternatives for commercializing MosaiQ in the patient market;

•

our ability to manufacture and sell our conventional reagent products, including the costs and timing of ~~any such distribution.~~

~~While Credit Suisse has advised that~~ further expansion of our sales and marketing efforts;

•

the ~~credit assets held by the funds are covered by insurance that potentially will be available to cover losses the funds would incur if any~~impact of the ~~obligors~~COVID-19 pandemic on the ~~funds’ credit assets were~~global economy, our business and our development timeline for MosaiQ;

•

our ability to ~~default,~~recoup the remaining approximately $21.4 million of funds invested in two funds that have suspended redemptions;

•

our ability to collect our accounts receivable;

•

our ability to generate cash from operations;

•

any acquisition of businesses or technologies that we ~~do not know if the funds will incur losses (net of insurance) on the credit assets held by the funds. We believe,~~may undertake; and ~~have advised Credit Suisse, that any such losses should be borne by Credit Suisse.~~

•

our ability to penetrate our existing market and new markets.

We expect to fund our operations in the near-term, including the ongoing development of MosaiQ through successful field trial completion, achievement of required regulatory authorizations and commercialization from a combination of funding sources. These expected funding sources include the use of existing available cash and short-term investment balances, the sale of rights and other assets, and the issuance of new equity or debt.

As of September 30, 2021, we had available cash, cash equivalents and short-term investments of $141.8 million and $8.3 million of restricted cash held as part of the arrangements relating to our Secured Notes and the lease of our property in Eysins, Switzerland.

~~Cash Flows for the six month ended September 30, 2021 and 2020~~

~~Operating activities~~

Net cash used in operating activities was $58.7 million during the six month period ended September 30, 2021, which included net losses of $54.4 million offset by non-cash items of $3.9 million. Non-cash items were depreciation and amortization expense of $3.9 million, share-based compensation expense of $3.2 million, a reduction from the change in fair value of convertible loan derivatives of $7.3 million, Swiss pension costs of $0.4 million, amortization of deferred debt issue costs, discount, and royalties of $2.2 million, accrued preference share dividends of $0.5 million, deferred lease rentals of $0.4 million and income taxes of $0.6 million. We also experienced a net cash outflow of $8.2 million from changes in operating assets and liabilities during the period, consisting of a $6.0 million reduction in accrued compensation and benefits, a $3.1 million increase in inventories, and a $2.9 million increase in other

~~- 28 -~~

~~assets and offset by $3.6 million increase in accounts payable and accrued liabilities and a $0.2 million reduction in accounts receivables.~~

Net cash used in operating activities was $30.6 million during the six month period ended September 30, 2020, which included net losses of $40.0 million offset by non-cash items of $12.3 million. Non-cash items were depreciation and amortization expense of $4.1 million, share-based compensation expense of $2.3 million, Swiss pension costs of $0.5 million, amortization of deferred debt issue costs, discount, and royalties of $4.8 million, accrued preference share dividends of $0.5 million and deferred lease rentals of $0.4 million, and a reduction of income taxes of $0.3 million. We also experienced a net cash outflow of $2.9 million from changes in operating assets and liabilities during the period, consisting of a $2.2 million reduction in accrued compensation and benefits, a $1.4 million increase in inventories and a $1.8 million increase in other assets, offset by a $1.1 million reduction in accounts receivables and a $1.4 million increase in accounts payable and accrued liabilities.

~~Investing activities~~

Net cash provided by investing activities was $43.0 million for the six month period ended September 30, 2021. We spent $1.7 million on purchases of property and equipment in the six month period ended September 30, 2021, which was mainly related to purchasing MosaiQ instruments and investments in our IT infrastructure. We also received distributions on our short-term money market investments of $29.7 million from CSAM in the six month period ended September 30, 2021, received $19.5 million from selling other short term investments and invested $4.5 million in other short-term money market investments.

Net cash used in investing activities was $30.3 million for the six month period ended September 30, 2020. We spent $2.1 million on purchases of property and equipment in the six month period ended September 30, 2020, which was mainly related to purchasing MosaiQ instruments. We also increased our short-term money market investments by $28.2 million in the six month period ended September 30, 2020.

~~Financing activities~~

Net cash provided by financing activities was $88.0 million during the six month period ended September 30, 2021, consisting of $100.5 million generated from the issuance of the Convertible Notes, net of debt issue costs, offset by $12.1 million repayment of the Secured Notes, expenses related to restricted stock units vested of $0.1 million and $0.3 million of repayments on finance leases. Net cash provided by financing activities was $80.5 million during the six month period ended September 30, 2020, consisting of $80.7 million generated from the issuance of ordinary shares on September 15, 2020 and $0.1 million generated from the exercise of share options, offset by $0.3 million of repayments on finance leases.

~~Operating and Capital Expenditure Requirements~~

We have not achieved profitability on an annual basis since we commenced operations in 2007 and we expect to incur net losses for at least the next fiscal year. As we move towards the commercial launch of MosaiQ in the donor testing market, we expect our operating expenses during the year ended March 31, 2022 to be similar to those of the year ended March 31, 2021, as we continue to invest in growing our customer base, expanding our marketing and distribution channels, completing field trials and regulatory filings, hiring additional employees and investing in other product development opportunities while our development expenditures on MosaiQ~~decrease.~~

As of September 30, 2021, we had $141.8 million of available cash, cash equivalents and short-term investments and $8.3 million of restricted cash held as part of the arrangements relating to our Secured Notes and the lease of our property in Eysins, Switzerland.

~~Our future capital requirements will depend on many factors, including:~~

•

~~our progress in developing and commercializing MosaiQ and the cost required to complete development, obtain regulatory approvals and complete our manufacturing scale up;~~

•

~~our ability to pursue successful alternatives for commercializing MosaiQ in the patient market;~~

•

~~our ability to manufacture and sell our conventional reagent products, including the costs and timing of further expansion of our sales and marketing efforts;~~

•

~~the impact of the COVID-19 pandemic on the global economy, our business and our development timeline for MosaiQ;~~

•

~~our ability to recoup the remaining approximately $23.6 million of funds invested in two funds that have suspended redemptions;~~

•

~~our ability to collect our accounts receivable;~~

•

~~our ability to generate cash from operations;~~

~~- 29 -~~

•

~~any acquisition of businesses or technologies that we may undertake; and~~

•

~~our ability to penetrate our existing market and new markets.~~

We currently expect that the additional net cash generated from the Convertible Notes issuance combined with our existing available cash and short-term investment balances are adequate to meet our forecasted cash requirements for the next twelve months.

We expect to fund our operations in the near-term, including the ongoing development of MosaiQ through successful field trial completion, achievement of required regulatory authorizations and commercialization from a combination of funding sources. These expected funding sources include the use of existing available cash and short-term investment balances, the sale of rights and other assets, and the issuance of new equity or debt.

Critical Accounting Policies and Significant Judgments and Estimates

We have prepared our condensed consolidated financial statements in accordance with U.S. GAAP. Our preparation of these condensed consolidated financial statements requires us to make estimates, assumptions and judgments that affect the reported amounts of assets, liabilities, expenses and related disclosures at the date of the consolidated financial statements, as well as revenue and expenses during the reporting periods. We evaluate our estimates and judgments on an ongoing basis. We base our estimates on historical experience and on various other factors that we believe are reasonable under the circumstances, the results of which form the basis for making judgments about the carrying value of assets and liabilities that are not readily apparent from other sources. Actual results could therefore differ materially from these estimates under different assumptions or conditions.

For a detailed discussion of our critical accounting policies, see Note 1, ~~‘Organization~~"Organization and Summary of Significant Accounting Policies.’" to our Annual Report on Form ~~10-K/A~~10-K for the year ended March 31, ~~2021.~~2022. For a detailed description of our significant judgements and estimates, see ~~“Management’s~~"Management’s Discussion and Analysis of Financial Condition and Results of ~~Operations”~~Operations" in our Annual Report on Form ~~10-K/A~~10-K for the year ended March 31, ~~2021. We have summarized material new significant judgements and estimates and critical accounting policies during the six month period ended September 30, 2021 below.~~ 2022.

~~Convertible loan derivatives~~

The Convertible Notes are accounted for in accordance with ASC 470-20, Debt with Conversion and Other Options (“ASC 470-20”) and ASC 815-40, Contracts in Entity’s Own Equity (“ASC 815-40”). Based upon the Company’s analysis, it was determined the Convertible Notes contain embedded features that need to be separately accounted for as a derivative liability component. The proceeds received from the issuance of the convertible debt instruments were bifurcated and recorded as a liability within convertible loan derivatives in the consolidated balance sheet. The convertible loan derivatives are measured at fair value and changes are recognized within other, net in the accompanying consolidated financial statements.

~~The fair value of the convertible loan derivatives have been determined by utilizing a single factor lattice model using market-based observable inputs. The value of these~~ ~~derivatives could vary materially based on changes in these inputs and any such changes could materially impact our reported results. See~~ ~~Note 3, “Debt” andNote 6, “Fair value measurement” to our condensed consolidated financial statements included in this Quarterly Report for additional information~~.

Recent Accounting Pronouncements

~~Except as discussed in Note 2, “Summary of Significant Accounting Policies,” we~~We did not adopt any other new accounting pronouncements during the ~~six~~three month period ended ~~September~~June 30, ~~2021~~2022 that had a significant effect on our condensed consolidated financial statements included in this Quarterly Report.

Item 3. Reserved

Item 4.4. Controls and Procedures

Evaluation of disclosure controls and procedures

Our management, with the participation of our Chief Executive Officer and Chief Financial Officer, has evaluated the effectiveness of our disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) as of the end of the period covered by this Quarterly Report on Form 10-Q. Management recognizes that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving their objectives and management necessarily applies its judgment in evaluating the cost-benefit relationship of possible controls and procedures. Based on such evaluation, our Chief Executive Officer and Chief Financial Officer have concluded that, as of ~~September~~June 30, ~~2021,~~ 2022, our disclosure controls and procedures

~~- 30 -~~

were ~~not~~ effective ~~at the reasonable assurance level due~~ to ~~a material weakness in internal control over financial reporting related~~ensure that information required to ~~the accounting for our Senior Secured Notes and royalty rights agreements which existed as of September 30, 2021.~~

~~Material Weakness in Internal Control over Financial Reporting~~

A material weakness is a deficiency, or a combination of deficiencies, in internal control over financial reporting, such that there is a reasonable possibility that a material misstatement of the company's annual or interim financial statements will not be ~~prevented or detected on a timely basis.~~

~~Based on its evaluation in accordance with the framework in Internal Control - Integrated Framework issued~~disclosed by ~~the Committee of Sponsoring Organizations of the Treadway Commission (2013 Framework), management identified a material weakness~~us in the ~~operation of our internal control related to the historical accounting of the Senior Secured Notes and royalty rights agreements originating in October 2016, August 2018, and June 2019.~~ ~~Specifically, management of the Company determined~~reports that it did not identify the correct accounting treatment at the time of entering into these transactions, and accounted for these instruments on a combined basis instead of treating these as separate freestanding financial instruments. This material weakness resulted in the restatement of the Company’s previously filed consolidated financial statements as of and for the fiscal year ended March 31, 2021 and 2020 and relevant unaudited condensed consolidated financial information for the fiscal year 2021 quarterly periods to correct errors in the Company’s accounting for its Senior Secured Notes and related royalty rights agreements. This also resulted in a restatement of our June 30, 2021 Form 10-Q.

~~Remediation Plan for Material Weakness in Internal Control over Financial Reporting~~

~~To remediate the material weakness identified above,~~ we ~~have implemented additional controls and procedures, which include but are not limited to:~~

•

~~increased involvement of external accounting specialists to assist and review complex, non-routine financing transactions entered into after March 31, 2021~~

•

~~management review (with the assistance of external accounting advisors) of the accounting treatment of all historical debt arrangements~~file or submit under ~~US GAAP.~~

Based on the foregoing process and remediation measures, management believes that the above mentioned control deficiency will be remediated, but the material weakness cannot be considered remediated until the applicable remedial controls operate for a sufficient period of time and management has concluded, through testing, that these controls are operating effectively.

~~Changes in Internal Control over Financial Reporting~~

~~There have been no changes in our internal control over financial reporting identified in management's evaluation pursuant to Rules 13a-15(d) or 15d-15(d) of~~ the Exchange Act ~~during~~is recorded, processed, summarized and reported, within the ~~Company’s second fiscal quarter of 2022 that materially affected,~~time periods specified in the SEC’s rules and forms, and is accumulated and communicated to our management, including our Chief Executive and Chief Financial Officers, or ~~are reasonably likely~~persons performing similar functions, as appropriate to ~~materially affect, the Company’s internal control over financial reporting.~~allow timely decisions regarding required disclosure.

- 23 -

PART II – OTHER INFORMATION

Item 1. Legal Proceedings

We are not currently party to any pending legal or governmental proceedings that we believe could have a material adverse effect on our business or financial condition. However, we may be subject to various claims and legal actions arising in the ordinary course of business from time to time.

Item 1A. Risk Factors

There have been no material changes in the risk factors described in Item 1A "Risk Factors" of our Annual Report on Form ~~10-K/A~~10-K for the year ended March 31, ~~2021.~~2022.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds

None.

Item 3. Defaults Upon Senior Securities

None.

~~- 31 -~~

Item 4. Mine Safety Disclosures

Not applicable.

Item 5. Other Information

None.

Item 6. Exhibits

The following is a list of exhibits filed as part of this Quarterly Report on Form 10-Q:


Exhibit No.		Description
~~31.1~~4.1		Sixth Supplemental Indenture dated as of July 6, 2022, by and among the Company, the Guarantors party thereto and U.S. Bank National Association as trustee and collateral agent
31.1		Certification of Manuel O. Méndez, Chief Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
31.2		Certification of Ali Kiboro, Chief Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
32.1		Certification of Manuel O. Méndez, Chief Executive Officer pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
32.2		Certification of Ali Kiboro, Chief Financial Officer pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
101		The following financial information from Company’s Quarterly Report on Form 10-Q for the quarter ended ~~September~~June 30, ~~2021~~2022 filed with the SEC, formatted in Inline eXtensible Business Reporting Language (Inline XBRL): (i) Condensed Consolidated Balance Sheets (unaudited), (ii) Condensed Consolidated Statements of Comprehensive Loss (unaudited), (iii) Condensed Consolidated Statements of Changes in Shareholders’ Deficit (unaudited), (iv) Condensed Consolidated Statements of Cash Flows (unaudited) and (v) Notes to Condensed Consolidated Financial Statements.
104		Cover Page Interactive Data File, formatted in Inline XBRL (included as Exhibit 101).

- 3224 -

SIGNATURES

~~SIGNATURES~~

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.


		QUOTIENT LIMITED

Date: ~~November 15, 2021~~August 9, 2022		/s/ Manuel O. Méndez
		Manuel O. Méndez Chief Executive Officer

Date: ~~November 15, 2021~~August 9, 2022

/s/ Ali Kiboro

Ali Kiboro

Chief Financial Officer

- 3325 -


Jersey, Channel Islands		Not Applicable
(State or other jurisdiction of incorporation or organization)		(I.R.S. Employer Identification No.)

~~B1,~~ Business Park Terre Bonne, Route de Crassier 13, 1262Eysins, Switzerland		Not Applicable
(Address of principal executive offices)		(Zip Code)


Title of each class	Trading Symbol	Name of each exchange on which registered
Ordinary Shares, nil par value	QTNT	The Nasdaq Global Market


	June 30, 2022			March 31, 2022
ASSETS
Current assets:
Cash and cash equivalents	$	46,153		$	65,059
Short-term investments		2,480			2,626
Trade accounts receivable, net		5,056			6,272
Inventories		22,082			22,036
Prepaid expenses and other current assets		10,918			5,761
Total current assets		86,689			101,754
Restricted cash		8,724			8,744
Long-term investments		14,604			15,467
Property and equipment, net		31,118			33,242
Operating lease right-of-use assets		28,494			29,411
Intangible assets, net		465			520
Deferred income taxes		123			123
Other non-current assets		4,373			4,728
Total assets	$	174,590		$	193,989
LIABILITIES AND SHAREHOLDERS' EQUITY (DEFICIT)
Current liabilities:
Accounts payable	$	5,504		$	4,524
Accrued compensation and benefits		6,507			8,503
Accrued expenses and other current liabilities		12,815			15,729
Current portion of operating lease liability		3,689			3,535
Current portion of finance lease obligation		406			537
Total current liabilities		28,921			32,828
Long-term debt, less current portion		236,348			233,313
Derivative liabilities		2,733			13,515
Operating lease liability, less current portion		27,845			28,753
Finance lease obligation, less current portion		358			388
Deferred income taxes		1,857			1,988
Defined benefit pension plan obligation		4,818			4,777
7% Cumulative redeemable preference shares		22,788			22,525
Total liabilities		325,668			338,087
Commitments and contingencies
Shareholders' equity (deficit):
Ordinary shares (nil par value) 135,683,559 and 102,611,397 issued and outstanding at June 30, 2022 and March 31, 2022 respectively		558,639			540,736
Additional paid in capital		48,033			46,399
Accumulated other comprehensive loss		6,160			(6,191	)
Accumulated deficit		(763,910	)		(725,042	)
Total shareholders' equity (deficit)		(151,078	)		(144,098	)
Total liabilities and shareholders' equity (deficit)	$	174,590		$	193,989

	September 30, 2021			March 31, 2021
ASSETS
Current assets:
Cash and cash equivalents	$	120,978		$	45,673
Short-term investments		20,792			65,999
Trade accounts receivable, net		5,000			5,323
Inventories		25,014			22,011
Prepaid expenses and other current assets		7,332			4,870
Total current assets		179,116			143,876
Restricted cash		8,302			9,024
Property and equipment, net		35,802			39,071
Operating lease right-of-use assets		20,720			22,011
Intangible assets, net		568			619
Deferred income taxes		240			255
Other non-current assets		4,845			4,956
Total assets	$	249,593		$	219,812
LIABILITIES AND SHAREHOLDERS' EQUITY (DEFICIT)
Current liabilities:
Accounts payable	$	5,488		$	4,659
Accrued compensation and benefits		6,367			12,343
Accrued expenses and other current liabilities		14,946			14,009
Current portion of long-term debt		—			24,167
Current portion of operating lease liability		3,192			3,446
Current portion of finance lease obligation		661			835
Total current liabilities		30,654			59,459
Long-term debt, less current portion		231,964			145,059
Convertible loan derivatives		20,632			—
Operating lease liability, less current portion		20,160			20,907
Finance lease obligation, less current portion		519			445
Deferred income taxes		1,706			1,152
Defined benefit pension plan obligation		7,286			6,896
7% Cumulative redeemable preference shares		22,000			21,475
Total liabilities		334,921			255,393
Commitments and contingencies
Shareholders' equity (deficit):
Ordinary shares (nil par value) 101,591,632 and 101,264,412 issued and outstanding at September 30, 2021 and March 31, 2021 respectively		540,733			540,813
Additional paid in capital		41,343			38,116
Accumulated other comprehensive loss		(13,095	)		(14,598	)
Accumulated deficit		(654,309	)		(599,912	)
Total shareholders' equity (deficit)		(85,328	)		(35,581	)
Total liabilities and shareholders' equity (deficit)	$	249,593		$	219,812


	Quarter ended June 30,
	2022			2021
OPERATING ACTIVITIES:
Net loss	$	(38,868	)	$	(27,292	)
Adjustments to reconcile net loss to net cash provided by operating activities:
Depreciation, amortization and loss on disposal of fixed assets		1,464			1,930
Share-based compensation		1,634			1,823
Increase in deferred lease rentals		387			176
Swiss pension obligation		223			188
Amortization of debt discount and unrealized foreign currency loss (gains) on debt		21,855			(1,641	)
Impairment of investments		995			0
Change in fair value of derivative instruments		(10,844	)		1,984
Accrued preference share dividends		263			263
Provision for income taxes		133			502
Net change in assets and liabilities:
Trade accounts receivable, net		834			893
Inventories		(1,122	)		(834	)
Accounts payable and accrued liabilities		(920	)		(2,382	)
Accrued compensation and benefits		(1,457	)		(4,181	)
Other assets and liabilities		(10,094	)		(3,482	)
Net cash used in operating activities		(35,518	)		(32,053	)
INVESTING ACTIVITIES:
Increase in short-term investments		0			(4,500	)
Realization of short-term investments		0			18,551
Purchase of property and equipment		(835	)		(1,405	)
Net cash (used in) from investing activities		(835	)		12,646
FINANCING ACTIVITIES:
Repayment of finance leases		(165	)		(213	)
Proceeds from issuance of long-term debt		0			104,222
Debt issuance costs		0			(3,732	)
Repayment of long-term debt		0			(12,083	)
Proceeds from (cost of) issuance of ordinary shares and warrants		17,903			(79	)
Net cash generated from financing activities		17,738			88,115
Effect of exchange rate fluctuations on cash and cash equivalents		(311	)		(552	)
Change in cash and cash equivalents		(18,926	)		68,156
Beginning cash and cash equivalents		73,803			54,697
Ending cash and cash equivalents	$	54,877		$	122,853
Reconciliation of cash, cash equivalents and restricted cash:
Cash and cash equivalents	$	46,153		$	114,547
Restricted cash	$	8,724		$	8,306
Total cash, cash equivalents and restricted cash	$	54,877		$	122,853


	Page

PART I – FINANCIAL INFORMATION		3	3
Item 1. Financial Statements		3	3
Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations		17	19
Item 3. Reserved		23	30
Item 4. Controls and Procedures		23	30
PART II – OTHER INFORMATION		24	31
Item 1. Legal Proceedings		24	31
Item 1A. Risk Factors		24	31
Item 2. Unregistered Sales of Equity Securities and Use of Proceeds		24	31
Item 3. Defaults Upon Senior Securities		24	31
Item 4. Mine Safety Disclosures		24	32
Item 5. Other Information		24	32
Item 6. Exhibits		24	32
Signatures		25	33


	Quarter ended September 30,						Six months ended September 30,						Quarter ended June 30,
	2021			2020			2021			2020			2022			2021
Revenue:
Product sales	$	9,284		$	8,543		$	18,325		$	17,467		$	8,814		$	9,041
Other revenues		183			7,523			231			7,523			0			48
Total revenue		9,467			16,066			18,556			24,990			8,814			9,089
Cost of revenue		(4,875	)		(4,499	)		(9,652	)		(9,913	)		(6,120	)		(4,777	)
Gross profit		4,592			11,567			8,904			15,077			2,694			4,312
Operating expenses:
Sales and marketing		(2,640	)		(2,231	)		(5,133	)		(4,474	)		(3,306	)		(2,493	)
Research and development, net of government grants		(15,754	)		(12,743	)		(29,285	)		(24,158	)		(14,146	)		(13,531	)
General and administrative expense:
Compensation expense in respect of share options and management equity incentives		(1,404	)		(1,324	)		(3,227	)		(2,284	)		(1,634	)		(1,823	)
Other general and administrative expenses		(8,618	)		(8,232	)		(16,971	)		(16,810	)		(9,403	)		(8,353	)
Total general and administrative expense		(10,022	)		(9,556	)		(20,198	)		(19,094	)		(11,037	)		(10,176	)
Total operating expense		(28,416	)		(24,530	)		(54,616	)		(47,726	)		(28,489	)		(26,200	)
Operating loss		(23,824	)		(12,963	)		(45,712	)		(32,649	)		(25,795	)		(21,888	)
Other income (expense):
Interest expense, net		(9,352	)		(6,297	)		(12,354	)		(13,228	)		(8,574	)		(3,002	)
Other, net		5,916			5,354			4,184			5,562			(4,366	)		(1,732	)
Other income (expense), net		(3,436	)		(943	)		(8,170	)		(7,666	)		(12,940	)		(4,734	)
Loss before income taxes		(27,260	)		(13,906	)		(53,882	)		(40,315	)		(38,735	)		(26,622	)
Provision for income taxes		155			151			(515	)		304			(133	)		(670	)
Net loss	$	(27,105	)	$	(13,755	)	$	(54,397	)	$	(40,011	)	$	(38,868	)	$	(27,292	)
Other comprehensive income (loss):
Change in fair value of effective portion of foreign currency cash flow hedges	$	(231	)	$	279		$	(343	)	$	276		$	0		$	(112	)
Unrealized gain (loss) on short-term investments		(72	)		(79	)		(193	)		(483	)
Foreign currency gain (loss)		1,852			(3,803	)		2,010			(3,632	)
Change in unrealized gain on short-term investments														7			(121	)
Foreign currency gain														12,330			158
Provision for pension benefit obligation		14			14			29			(148	)		14			15
Other comprehensive income (loss), net		1,563			(3,589	)		1,503			(3,987	)		12,351			(60	)
Comprehensive loss	$	(25,542	)	$	(17,344	)	$	(52,894	)	$	(43,998	)	$	(26,517	)	$	(27,352	)
Net loss available to ordinary shareholders - basic	$	(27,105	)	$	(13,755	)	$	(54,397	)	$	(40,011	)
Net loss available to ordinary shareholders - diluted	$	(33,858	)	$	(13,755	)	$	(54,397	)	$	(40,011	)
Loss per share - basic	$	(0.27	)	$	(0.16	)	$	(0.54	)	$	(0.49	)
Loss per share - diluted	$	(0.28	)	$	(0.16	)	$	(0.54	)	$	(0.49	)
Weighted-average shares outstanding - basic		101,567,664			83,949,195			101,479,690			82,227,052
Weighted-average shares outstanding - diluted		120,086,178			83,949,195			101,479,690			82,227,052
Net loss available to ordinary shareholders - basic and diluted													$	(38,868	)	$	(27,292	)
Loss per share - basic and diluted													$	(0.37	)	$	(0.27	)
Weighted-average shares outstanding - basic and diluted														104,591,840			101,390,749

	Ordinary shares					Additional paid in		Accumulated Other Comprehensive			Accumulated			Total Shareholders'
	Shares		Amount			capital		Loss			Deficit			Equity (Deficit)
June 30, 2021		101,527,188		540,734			39,939		(14,658	)		(627,204	)		(61,189	)
Issue of shares upon exercise of incentive share options and vesting of RSUS		64,444		(1	)		—		—	��		—			(1	)
Net loss		—		—			—		—			(27,105	)		(27,105	)
Change in fair value of the effective portion of foreign currency cash flow hedges		—		—			—		(231	)		—			(231	)
Change in unrealized gain in short-term investments		—		—			—		(72	)		—			(72	)
Foreign currency gain (loss) on:
Long-term investment nature intra-entity balances		—		—			—		(5,378	)		—			(5,378	)
Retranslation of foreign entities		—		—			—		7,230			—			7,230
Provision for pension benefit obligation		—		—			—		14			—			14
Other comprehensive loss									1,563						1,563
Stock-based compensation		—		—			1,404		—			—			1,404
September 30, 2021		101,591,632		540,733			41,343		(13,095	)		(654,309	)		(85,328	)

Risk-free interest rate		1.64	%
Expected lives (years)	6
Volatility		74.19	%
Dividend yield		—
Grant date fair value (per share)	$	3.83
Number granted		1,150,504

	September 30, 2021		September 30, 2020
Ordinary shares issuable on conversion of Senior Convertible Notes at $5.67 per share⁽¹⁾		-		-
Restricted share units awarded		2,756,697		854,422
Ordinary shares issuable on exercise of options to purchase ordinary shares		2,801,809		1,899,280
Ordinary shares issuable on exercise of warrants at $16.14 per share		111,525		111,525
Ordinary shares issuable on exercise of warrants at $9.375 per share		64,000		64,000
		5,734,031		2,929,227

	Six months ended September 30
	2021						2020						Change
	Amount			% of revenue			Amount			% of revenue			Amount			%
	(in thousands, except percentages)
Revenue:
Product sales	$	18,325			99	%	$	17,467			70	%	$	858			5	%
Other revenues		231			1	%		7,523			30	%		(7,292	)		-97	%
Total revenue		18,556			100	%		24,990			100	%		(6,434	)		-26	%
Cost of revenue		9,652			52	%		9,913			40	%		(261	)		-3	%
Gross profit		8,904			48	%		15,077			60	%		(6,173	)		-41	%
Operating expenses:
Sales and marketing		5,133			28	%		4,474			18	%		659			15	%
Research and development		29,285			158	%		24,158			97	%		5,127			21	%
General and administrative		20,198			109	%		19,094			76	%		1,104			6	%
Total operating expenses		54,616			294	%		47,726			191	%		6,890			14	%
Operating (loss)		(45,712	)		-246	%		(32,649	)		-131	%		(13,063	)		40	%
Other income (expense):
Interest expense, net		(12,354	)		-67	%		(13,228	)		-53	%		874			-7	%
Other, net		4,184			23	%		5,562			22	%		(1,378	)		-25	%
Total other expense, net		(8,170	)		-44	%		(7,666	)		-31	%		(504	)		7	%
Loss before income taxes		(53,882	)		-290	%		(40,315	)		-161	%		(13,567	)		34	%
Provision for income taxes		(515	)		-3	%		304			—			(819	)		-269	%
Net loss	$	(54,397	)		-293	%	$	(40,011	)		-160	%	$	(14,386	)		36	%

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Non-accelerated filer

Smaller reporting company

Emerging growth company