UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549
FORM 10-Q

(Mark One)
xQUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended September 30, 2017March 31, 2021
or
oTRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from              to  
COMMISSION FILE NO. 001-36905
SeaSpine Holdings Corporation
(EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)
DELAWAREDelaware47-3251758
(STATE OR OTHER JURISDICTION OF

INCORPORATION OR ORGANIZATION)
(I.R.S. EMPLOYER

IDENTIFICATION NO.)
5770 Armada Drive, Carlsbad, California92008
(ADDRESS OF PRINCIPAL EXECUTIVE OFFICES)(ZIP CODE)
5770 Armada Drive, Carlsbad, CA 92008
(Address of principal executive offices) (zip code)
REGISTRANT’S TELEPHONE NUMBER, INCLUDING AREA CODE: (760) 727-8399
Securities registered pursuant to Section 12(b) of the Act:
Title of each classTrading Symbol(s)Name of each exchange on which registered
Common StockSPNEThe Nasdaq Global Select Market
Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.    Yes  x   No  o
Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).    Yes  x    No  o
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer”, “accelerated filer”, “smaller reporting company”, and "emerging growth company" in Rule 12b-2 of the Exchange Act.



Large accelerated fileroAccelerated filer
x
Large acceleratedNon-accelerated fileroAccelerated filerSmaller reporting company
x
Non-accelerated filer
o  (Do not check if a smaller reporting company)
Smaller reporting companyo
Emerging growth company
x
o
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o
Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).    Yes  o  No  ý

The number of shares of the registrant’s common stock, $0.01 par value, outstanding as of October 30, 2017April 29, 2021 was 13,429,128.

33,161,083.








SEASPINE HOLDINGS CORPORATION
INDEX

Page
Number
Page
Number
Exhibit 31.1
Exhibit 31.2
Exhibit 32.1
Exhibit 32.2
EX-101 INSTANCE DOCUMENT
EX-101 SCHEMA DOCUMENT
EX-101 CALCULATION LINKBASE DOCUMENT
EX-101 DEFINITION LINKBASE DOCUMENT
EX-101 LABELS LINKBASE DOCUMENT
EX-101 PRESENTATION LINKBASE DOCUMENT







PART I. FINANCIAL INFORMATION

Item 1. Financial Statements

SEASPINE HOLDINGS CORPORATION
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited)
(In thousands, except per share data)
 
 Three Months Ended September 30, Nine Months Ended September 30,
 2017 2016 2017 2016
Total revenue, net$31,742
 $31,741
 $97,832
 $96,341
Cost of goods sold12,176
 13,881
 39,342
 42,094
Gross profit19,566
 17,860
 58,490
 54,247
Operating expenses:       
Selling, general and administrative23,674
 23,803
 71,893
 76,166
Research and development2,834
 2,600
 9,228
 8,534
Intangible amortization792
 955
 2,376
 3,517
Total operating expenses27,300
 27,358
 83,497
 88,217
Operating loss(7,734) (9,498) (25,007) (33,970)
Other income (expense), net215
 (59) 387
 (33)
Loss before income taxes(7,519) (9,557) (24,620) (34,003)
Benefit for income taxes(57) (103) (12) (559)
Net loss$(7,462) $(9,454) $(24,608) $(33,444)
Net loss per share, basic and diluted$(0.58) $(0.84) $(2.04) $(2.98)
Weighted average shares used to compute basic and diluted net loss per share12,815
 11,271
 12,079
 11,206



 Three Months Ended March 31,
 20212020
Total revenue, net$41,954 $36,111 
Cost of goods sold15,366 13,812 
Gross profit26,588 22,299 
Operating expenses:
Selling and marketing23,399 20,476 
General and administrative10,427 8,554 
Research and development4,506 3,895 
Intangible amortization792 792 
Impairment of intangible assets1,325 
Total operating expenses39,124 35,042 
Operating loss(12,536)(12,743)
Other (expense) income, net(159)227 
Loss before income taxes(12,695)(12,516)
Provision for income taxes25 35 
Net loss$(12,720)$(12,551)
Net loss per share, basic and diluted$(0.46)$(0.48)
Weighted average shares used to compute basic and diluted net loss per share27,913 26,420 
The accompanying notes are an integral part of these condensed consolidated financial statements.
4





SEASPINE HOLDINGS CORPORATION
CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS
(Unaudited)
(In thousands)

 Three Months Ended September 30, Nine Months Ended September 30,
 2017 2016 2017 2016
Net loss$(7,462) $(9,454) $(24,608) $(33,444)
Other comprehensive income       
Foreign currency translation adjustments166
 45
 567
 131
Comprehensive loss$(7,296) $(9,409) $(24,041) $(33,313)




 Three Months Ended March 31,
 20212020
Net loss$(12,720)$(12,551)
Other comprehensive (loss) income
Foreign currency translation adjustments(357)(164)
Unrealized gain on investments190 
Comprehensive loss$(13,077)$(12,525)
The accompanying notes are an integral part of these condensed consolidated financial statements.






5





SEASPINE HOLDINGS CORPORATION
CONDENSED CONSOLIDATED BALANCE SHEETS
(Unaudited)
(In thousands, except par value data)
September 30, 2017 December 31, 2016March 31, 2021December 31, 2020
   
ASSETS   ASSETS
Current assets:   Current assets:
Cash and cash equivalents$16,689
 $14,566
Cash and cash equivalents$87,749 $76,813 
Trade accounts receivable, net of allowances of $519 and $48319,822
 20,982
Inventories42,276
 45,299
Trade accounts receivable, net of allowances of $123 and $192Trade accounts receivable, net of allowances of $123 and $19225,030 26,154 
Inventories, netInventories, net58,182 54,041 
Prepaid expenses and other current assets2,477
 1,813
Prepaid expenses and other current assets2,729 3,884 
Total current assets81,264
 82,660
Total current assets173,690 160,892 
Property, plant and equipment, net21,864
 21,863
Property, plant and equipment, net35,779 31,422 
Right of use assetsRight of use assets7,274 7,658 
Intangible assets, net36,859
 41,785
Intangible assets, net13,373 13,883 
Other assets718
 857
Other assets300 546 
Total assets$140,705
 $147,165
Total assets$230,416 $214,401 
LIABILITIES AND STOCKHOLDERS' EQUITY   LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:   Current liabilities:
Short-term debt$
 $445
Accounts payable, trade7,930
 8,537
Accounts payable, trade12,086 5,006 
Accrued compensation5,817
 4,393
Accrued compensation7,346 8,198 
Accrued commissions4,564
 4,398
Accrued commissions9,051 8,199 
Contingent consideration liabilities900
 2,855
Short-term debtShort-term debt1,393 1,114 
Short-term lease liabilityShort-term lease liability2,159 2,147 
Other accrued expenses and current liabilities3,979
 3,790
Other accrued expenses and current liabilities7,893 6,063 
Total current liabilities23,190
 24,418
Total current liabilities39,928 30,727 
Long-term borrowings under credit facility
 3,835
Contingent consideration liabilities3,632
 5,125
Long-term debtLong-term debt24,781 5,059 
Long-term lease liabilityLong-term lease liability6,349 6,802 
Other liabilities2,927
 2,810
Other liabilities91 95 
Total liabilities29,749
 36,188
Total liabilities71,149 42,683 
   
Commitments and contingencies
 
Commitments and contingencies00
Stockholders' equity:   Stockholders' equity:
Preferred stock, $0.01 par value; 15,000 authorized; no shares issued and outstanding at September 30, 2017 and December 31, 2016
 
Common stock, $0.01 par value; 60,000 authorized; 13,429 and 11,258 shares issued and outstanding at September 30, 2017 and December 31, 2016, respectively134
 113
Preferred stock, $0.01 par value; 15,000 authorized; 0 shares issued and outstanding at March 31, 2021 and December 31, 2020Preferred stock, $0.01 par value; 15,000 authorized; 0 shares issued and outstanding at March 31, 2021 and December 31, 2020
Common stock, $0.01 par value; 60,000 authorized; 27,948 and 27,729 shares issued and outstanding at March 31, 2021 and December 31, 2020, respectivelyCommon stock, $0.01 par value; 60,000 authorized; 27,948 and 27,729 shares issued and outstanding at March 31, 2021 and December 31, 2020, respectively279 277 
Additional paid-in capital204,752
 180,753
Additional paid-in capital389,198 388,574 
Accumulated other comprehensive income1,839
 1,272
Accumulated other comprehensive income1,767 2,124 
Accumulated deficit(95,769) (71,161)Accumulated deficit(231,977)(219,257)
Total stockholders' equity110,956
 110,977
Total stockholders' equity159,267 171,718 
Total liabilities and stockholders' equity$140,705
 $147,165
Total liabilities and stockholders' equity$230,416 $214,401 
The accompanying notes are an integral part of these condensed consolidated financial statements.




6



SEASPINE HOLDINGS CORPORATION
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(Unaudited)
(In thousands)
 Nine Months Ended September 30,
 2017 2016
OPERATING ACTIVITIES:   
Net loss$(24,608) $(33,444)
Adjustments to reconcile net loss to net cash used in operating activities:   
Depreciation and amortization8,184
 8,984
Instrument replacement expense1,146
 950
Impairment of spinal instruments
 919
Provision for excess and obsolete inventories3,229
 4,057
Amortization of debt issuance costs104
 105
Deferred income tax provision (benefit)103
 (80)
Stock-based compensation4,505
 5,406
Gain from change in fair value of contingent consideration liabilities(897) 
Changes in assets and liabilities:   
Accounts receivable1,405
 4,182
Inventories1,814
 87
Prepaid expenses and other current assets(653) 1,051
Other non-current assets(11) 102
Accounts payable(1,160) (3,941)
Accrued commissions166
 (277)
Other accrued expenses and current liabilities2,600
 1,289
Other non-current liabilities(36) 204
Net cash used in operating activities(4,109) (10,406)
INVESTING ACTIVITIES:   
Purchases of property and equipment(5,518) (5,707)
Additions to technology assets(200) (1,150)
Net cash used in investing activities(5,718) (6,857)
FINANCING ACTIVITIES:   
Borrowings under credit facility
 3,300
Borrowings under short-term debt
 1,202
Repayments of credit facility(4,020) 
Repayments of short-term debt(445) (378)
Proceeds from issuance of common stock- employee stock purchase plan and exercise of stock options488
 356
Proceeds from issuance of common stock, net of offering costs- ATM transactions15,557
 
Repurchases of common stock for income tax withheld upon vesting of restricted stock awards(48) (25)
Net cash provided by financing activities11,532
 4,455
Effect of exchange rate changes on cash and cash equivalents418
 187
Net change in cash and cash equivalents2,123
 (12,621)
Cash and cash equivalents at beginning of period14,566
 33,429
Cash and cash equivalents at end of period$16,689
 $20,808
Non-cash operating activities:   
Settlement of bonus in payment of restricted stock units$970
 $
Non-cash investing activities:   
Property and equipment in liabilities$972
 $1,556
Fair value of intangible assets acquired through acquisition of business (see Note 8)
$
 $8,300
Fair value of contingent consideration liabilities in connection with acquisition of business$
 $8,300


Settlement of contingent closing consideration liabilities in connection with acquisition of business (see Note 8)

$2,548
 $



The accompanying notes are an integral part of these condensed consolidated financial statements.



SEASPINE HOLDINGS CORPORATION
CONDENSED CONSOLIDATED STATEMENT OF EQUITY
(Unaudited)
(In thousands)


  Common Stock  Additional  Accumulated Other   Total
 Number of    Paid-In Comprehensive Accumulated Stockholders'
 Shares  Amount  Capital Income Deficit  Equity
Balance December 31, 201611,258
 $113
 $180,753
 $1,272
 $(71,161) $110,977
Net loss
 
 
 
 (24,608) (24,608)
Foreign currency translation adjustment
 
 
 567
 
 567
Restricted stock awards/units issued252
 2
 968
 
 
 970
Issuance of common stock under employee stock purchase plan71
 1
 452
 
 
 453
Issuance of common stock- NLT Spine Ltd contingent closing consideration350
 3
 2,545
 
 
 2,548
Issuance of common stock, net of offering costs- ATM transactions1,500
 15
 15,542
 
 
 15,557
Issuance of common stock- exercise of stock options5
 
 35
 
 
 35
Repurchases of common stock for income tax withheld upon vesting of restricted stock awards(7) 
 (48) 
 
 (48)
Stock-based compensation
 
 4,505
 
 
 4,505
Balance September 30, 201713,429
 $134
 $204,752
 $1,839
 $(95,769) $110,956


 Three Months Ended March 31,
 20212020
OPERATING ACTIVITIES:
Net loss$(12,720)$(12,551)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization2,747 2,608 
Instrument replacement expense730 379 
Impairment of intangible assets1,325 
Impairment of spinal instruments234 
Provision for excess and obsolete inventories1,321 2,104 
Stock-based compensation2,546 1,983 
Other(36)(23)
Changes in assets and liabilities:
Accounts receivable1,021 4,853 
Inventories(5,411)(2,354)
Prepaid expenses and other current assets1,150 937 
Other non-current assets228 (7)
Accounts payable3,941 3,458 
Accrued commissions850 (2,021)
Other accrued expenses and current liabilities683 (3,628)
Other non-current liabilities(8)(7)
Net cash used in operating activities(2,958)(2,710)
INVESTING ACTIVITIES:
Purchases of property and equipment(3,750)(2,196)
Additions to technology assets(350)(850)
Purchases of short-term investments(25,007)
Net cash used in investing activities(4,100)(28,053)
FINANCING ACTIVITIES:
Borrowings under credit facility20,000 
Proceeds from exercise of stock options496 902 
Proceeds from issuance of common stock, net of offering costs91,622 
Repurchases of common stock for income tax withheld upon vesting of restricted stock awards and restricted stock units(2,418)(1,855)
Payment of contingent royalty consideration liabilities in connection with acquisition of
business
(19)(33)
Net cash provided by financing activities18,059 90,636 
Effect of exchange rate changes on cash and cash equivalents(65)(66)
Net change in cash and cash equivalents10,936 59,807 
Cash and cash equivalents at beginning of period76,813 20,199 
Cash and cash equivalents at end of period$87,749 $80,006 
Supplemental cash flow information:
Interest paid$63 $38 
Income taxes paid$10 $14 
Non-cash investing activities:
Property and equipment in liabilities$4,556 $1,055 
Intangible assets in liabilities$350 $
The accompanying notes are an integral part of these condensed consolidated financial statements.

7





SEASPINE HOLDINGS CORPORATION
CONDENSED CONSOLIDATED STATEMENTS OF EQUITY
(Unaudited)
(In thousands)
 Common Stock Additional Accumulated OtherTotal
Number of Paid-InComprehensiveAccumulatedStockholders'
Shares Amount CapitalIncomeDeficit Equity
Balance December 31, 202027,729 $277 $388,574 $2,124 $(219,257)$171,718 
Net loss— — — — (12,720)(12,720)
Foreign currency translation adjustment— — — (357)— (357)
Restricted stock issued175 — — 
Issuance of common stock - exercise of stock options44 496 — — 496 
Repurchases of common stock for income tax withheld upon vesting of restricted stock awards and restricted stock units— — (2,418)— — (2,418)
Stock-based compensation— — 2,546 — — 2,546 
Balance March 31, 202127,948 279 389,198 1,767 (231,977)159,267 
 Common Stock Additional Accumulated OtherTotal
Number of Paid-InComprehensiveAccumulatedStockholders'
Shares Amount CapitalIncomeDeficit Equity
Balance December 31, 201919,124 $191 $284,211 $1,434 $(176,076)$109,760 
Net loss— — — — (12,551)(12,551)
Foreign currency translation adjustment— — — (164)— (164)
Unrealized gain on short-term investments— — — 190 — 190 
Restricted stock issued213 — — 
Issuance of common stock - public offering7,820 78 91,544 — — 91,622 
Issuance of common stock- exercise of stock options80 901 — — 902 
Repurchases of common stock for income tax withheld upon vesting of restricted stock awards and restricted stock units— (1,855)— — (1,855)
Stock-based compensation— — 1,983 — — 1,983 
Balance March 31, 202027,237 272 376,784 1,460 (188,627)189,889 
The accompanying notes are an integral part of these condensed consolidated financial statements.
8



SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS


1. BUSINESS AND BASIS OF PRESENTATION

Business

SeaSpine Holdings Corporation was incorporated in Delaware on February 12, 2015 in connection with the spin-off of the orthobiologics and spinal implant business of Integra LifeSciences Holdings Corporation, a diversified medical technology company. The spin-off occurred on July 1, 2015. Unless the context indicates otherwise, (i) references to "SeaSpine" or the "Company" refer to SeaSpine Holdings Corporation and its wholly-owned subsidiaries,subsidiaries.
SeaSpine is a global medical technology company focused on the design, development and (ii) referencescommercialization of surgical solutions for the treatment of patients suffering from spinal disorders. SeaSpine has a comprehensive portfolio of orthobiologics and spinal implant solutions to "Integra" refermeet the varying combinations of products that neurosurgeons and orthopedic spine surgeons need to Integra LifeSciences Holdings Corporationperform fusion procedures in the lumbar, thoracic and its subsidiaries other than SeaSpine.

cervical spine. The Company believes this broad combined portfolio of orthobiologics and spinal implant products is essential to meet the “complete solution” requirements of such surgeons.
Basis of Presentation and Principles of Consolidation
The Company prepared the unaudited interim condensed consolidated financial statements included in this report in accordance with accounting principles generally accepted in the U.S. (GAAP) for interim financial information and the rules and regulations of the Securities and Exchange Commission (SEC) related to quarterly reports on Form 10-Q.
The Company’s financial statements are presented on a consolidated basis. The consolidated financial statements include the accounts of the Company and its wholly-owned subsidiaries. Intercompany accounts and transactions have been eliminated in consolidation. The unaudited interim condensed consolidated financial statements do not include all information and disclosures required by GAAP for annual audited financial statements and should be read in conjunction with the Company’s consolidated financial statements and notes thereto for the year ended December 31, 20162020 included in the Company’s Annual Report on Form 10-K filed with the SEC. In the opinion of management, the unaudited interim condensed consolidated financial statements included in this report have been prepared on the same basis as the Company's audited consolidated financial statements and include all adjustments (consisting only of normal recurring adjustments) necessary for a fair statement of the financial position, results of operations, cash flows, and statement of equity for periods presented. The results for the three and nine months ended September 30, 2017March 31, 2021 are not necessarily indicative of the results expected for the full year. The condensed consolidated balance sheet as of December 31, 20162020 was derived from the audited consolidated financial statementsbalance sheet for the year ended December 31, 2016.2020. Certain prior year amounts have been reclassified for consistency with the current year presentation. These reclassifications had no effect on the reported results of operations.
Under current SEC rules, generally, a company qualifies as a "smaller reporting company" if it has a public float of less than $250 million as of the last business day of its most recently completed second fiscal quarter. If a company qualifies as a smaller reporting company on that date, it may elect to reflect that determination and use the smaller reporting company scaled disclosure accommodations in its subsequent SEC filings until the beginning of the first quarter of the fiscal year following the date it determines it does not qualify as a smaller reporting company. The Company's public float as of June 30, 2020, the last business day of its most recent second fiscal quarter, was less than $250 million, and as such, the Company qualifies as a smaller reporting company, elected to reflect that determination and intends to use certain of the scaled disclosure accommodations in its SEC filings made during and for the year ended December 31, 2021.

Concentration of Risk
On March 1, 2021, the Company and PcoMed, LLC (PcoMed) entered into a supply agreement (the Supply Agreement).
Pursuant to the Supply Agreement, PcoMed granted the Company a worldwide right to sell and commercialize any implantable spinal surgery interbody and/or intervertebral medical device designed and/or manufactured by or for the Company treated by PcoMed with certain proprietary PcoMed technology (Processed Parts) for use in spinal interbody and/or intervertebral surgical methods and procedures. The right is exclusive to the Company through January 14, 2022; thereafter, it will be non-exclusive. The Supply Agreement replaces and supersedes a prior supply agreement between the Company and PcoMed entered into in May 2013, which expired on January 15, 2021.
For the three months ending March 31, 2021 and 2020, the sales of products incorporating the NanoMetalene® technology provided under the Supply Agreement exceeded 10% of the Company's revenue.

9

SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)
Pursuant to the Supply Agreement, PcoMed, which serves as the sole supplier of Processed Parts, will supply up to designated minimum amounts of Processed Parts per week and per month per the Company's request. In addition, if requested by the Company, PcoMed must use commercially reasonable efforts to supply Processed Parts in excess of those minimum amounts. The Company agreed to pay PcoMed (a) a low single digit royalty on a monthly basis on the Company's net sales of all Processed Parts, (b) a minimum processing fee for each contract year during the term of the Supply Agreement, payable in four equal quarterly installments, which offsets on a dollar-for-dollar basis the processing fees the Company would otherwise pay for Processed Parts each contract year and (c) additional processing fees payable monthly based on the number and type of Processed Parts supplied by PcoMed.

The Supply Agreement contains customary representations, warranties, covenants and indemnification obligations on the part of both parties. Each of the Company and PcoMed retain the rights to their respective intellectual property. The Supply Agreement may be terminated by the Company or PcoMed for cause in the event of an uncured material default or breach or a bankruptcy or similar proceeding. Unless terminated earlier pursuant to its terms, the term of the Supply Agreement is March 1, 2021 through January 14, 2024. During the term of the Supply Agreement, PcoMed agreed not to enter into any agreement or consummate any transaction with any third party relating to a change in control of PcoMed without first affording the Company, in accordance with the terms of the Supply Agreement, the opportunity to negotiate for the acquisition of PcoMed.

The Company's financial instruments that are exposed to concentrations of credit risk consist primarily of cash. Cash balances are maintained primarily at major financial institutions in the United States and exceed the regulatory limit of $250,000 insured by the Federal Deposit Insurance Corporation (FDIC). The Company has not experienced any credit losses associated with its cash balances.
2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

Use of Estimates

The preparation ofPreparing consolidated financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent liabilities, and the reported amounts of revenues and expenses. Significant estimates affecting amounts reported or disclosed in the consolidated financial statements include allowances for doubtful accounts receivable and sales returns and other credits, net realizable value of inventories, discount rates and estimated projected cash flows used to value and test impairments of identifiable intangible and long-lived assets, assumptions related to the timing and probability of product launch dates, discount rates matched to the estimated timing of payments, probability of success rates and discount adjustments on the related cash flows for contingent considerations in business combinations, depreciation and amortization periods for identifiable intangible and long-lived assets, computation of taxes, valuation allowances recorded against deferred tax assets, the valuation of stock-based compensation and loss contingencies. These estimates are based on historical experience and on various other assumptions that are believed to be reasonable under the current circumstances. Actual results could differ from these estimates.

The full extent to which the COVID-19 pandemic will directly or indirectly impact the Company's business, results of operations and financial condition, including revenues, expenses, manufacturing, research and development costs and employee-related compensation, will depend on future developments that are highly uncertain, including as a result of genetic variations of, or other information that may emerge concerning, COVID-19 and the actions taken to contain it or treat COVID-19, as well as the economic impact on local, regional, national and international customers and markets. The Company has made estimates of the impact of the pandemic within its financial statements and there may be changes to those estimates in future periods. Actual results may differ from these estimates.
Recent Accounting Standards Not Yet Adopted

The Company qualifies as an “emerging growth company” (EGC) pursuant to the provisions of the Jumpstart Our Business Startups (JOBS) Act and elected to take advantage of the extended transition period provided in Section 7(a)(2)(B) of the Securities Act of 1933, as amended, which permits EGCs to defer compliance with new or revised accounting standards (the EGC extension) until non-issuers are required to comply with such standards. Accordingly, so long as the Company continues to qualify as an EGC, the Company will not have to adopt or comply with new or revised accounting standards until non-issuers are required to adopt or comply with such standards.

In May 2014,June 2016, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update (ASU or Update) No. 2016-13, Financial Instruments - Credit Losses (Topic 326): Measurement of Credit Losses on Financial Instruments, which requires credit losses on most financial assets measured at amortized cost, including trade receivables, and certain other instruments to be measured using an expected credit loss model, referred to as the current expected credit loss (CECL) model. Under this model, entities will estimate credit losses over the entire contractual term of the instrument. The new standard will be effective for the Company beginning January 1, 2023. The FASB subsequently issued other related ASUs that amend ASU No. 2016-13 to provide clarification and additional guidance. The Company is evaluating the impact of this standard on its consolidated financial statements.
In April 2019, the FASB issued Update No. 2014-09, Revenue from Contracts with

2019-04, Codification Improvements to Topic 326, Financial Instruments-Credit Losses, Topic 815, Derivatives and Hedging, and Topic 825, Financial Instruments. This Update includes several amendments
9
10

SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)

Customers (Topic 606).to the FASB Accounting Standards Codification (Codification) intended to clarify, improve, or correct errors therein. Some amendments do not require transition guidance and are effective upon issuance. The new standard provides a five-step approach to be applied to all contracts with customers. The new standard also requires expanded disclosure about revenue recognition. The new standardamendments requiring transition guidance have the same effective date as amended by ASU 2015-14Update No. 2016-13 and will be effective for the Company beginning on January 1, 2019, and for interim periods within annual periods beginning on January 1, 2020.2023. The Company performed a preliminary assessment of the impact of this new standard on its consolidated financial statements. In assessing the impact, the Company has outlined all revenue streams, and has considered the five steps outlined in the standard for product sales, from which substantially all the Company's revenue is generated. The Company will continue to evaluate the future impact of the new standard throughout 2017.

In February 2016, the FASB issued Update No. 2016-02, Leases (Topic 842). The new standard requires lessees to recognize lease liabilities and corresponding right-of-use assets for all leases with lease terms of greater than twelve months. It also changes the definition of a lease and expands the disclosure requirements of lease arrangements. The new standard must be adopted using the modified retrospective approach. The standard will be effective for the Company beginning on January 1, 2020, and interim periods within annual periods beginning on January 1, 2021, with early adoption permitted. The Company does not plan to early adopt and expects to apply the transition practical expedients allowed by the standard. Note 11 to the Condensed Consolidated Financial Statements provides details on the Company’s current lease arrangements. While the Company continues to evaluate the impact of this new standard on its consolidated financial statements, the Company currently expects the primary impact will be to record right-of-use assets and lease liabilities for existing operating leases in the consolidated balance sheets. The Company does not currently expect the adoption of this new standard to have a material impact on its consolidated results of operations or cash flows.

In August 2016, the FASB issued Update No. 2016-15, Statement of Cash Flows (Topic 230): Classification of Certain Cash
Receipts and Cash Payments. This new standard addresses eight specific cash flow issues related to cash receipts and cash payments with the objective of reducing the existing diversity of presentation and classification in the statement of cash flows. The new standard will be effective for the Company beginning on January 1, 2019, and interim periods within annual periods beginning on January 1, 2020. Early adoption is permitted and should be applied using a retrospective transition method to each period presented. The Company is in the process of evaluating the impact of this standard on its consolidated financial statements.

Recently Adopted Accounting Standards
In May 2017,August 2018, the FASB issued Update No. 2017-09, Compensation- Stock Compensation (Topic 718): Scope of Modification Accounting. 2018-15, Intangibles-Goodwill and Other-Internal Use Software (Subtopic 350-40). The new standard provides guidance regarding which changesamendments in this Update align the requirements for capitalizing implementation costs incurred in a hosting arrangement that is a service contract with the requirements for capitalizing implementation costs incurred to the termsdevelop or conditions of a share-based payment award requireobtain internal-use software (and hosting arrangements that include an entity to apply modification accounting in Topic 718. The new standard will be effective for the Company beginning on January 1, 2018, and interim periods within annual periods beginning on January 1, 2018. The new standard should be applied prospectively to an award modified on or after the adoption date. The Company is in the process of evaluating the impact of this standard on its consolidated financial statements.

Recently Adopted Accounting Standards

In July 2015, the FASB issued Update No. 2015-11, Simplifying the Measurement of Inventory (Topic 330)internal-use software license). The new guidance
requires an entity to measure inventory within the scope of the amendment at the lower of cost and net realizable value. Net realizable value is the estimated selling price in the ordinary course of business, less reasonably predictable costs of completion, disposal, and transportation. The guidancestandard was effective for the Company beginning on January 1, 2017, and interim periods within annual periods beginning on January 1, 2018. Adoption2021. The adoption of this new guidance hasstandard had no material impact on the Company’sits consolidated financial statements.

In March 2020, the FASB issued Update No. 2020-04, Reference Rate Reform (Topic 848), Facilitation of the Effects of Reference Rate Reform on Financial Reporting. The amendments in this Update apply only to contracts, hedging relationships, and other transactions that reference LIBOR, or another reference rate expected to be discontinued, due to the reference rate reform. The new standard was effective for the Company beginning March 12, 2020. The adoption of this new standard had no material impact on its consolidated financial statements.
Net Loss Per Share

Basic and diluted net loss per share was calculated using the weighted-average number of shares of common stock outstandingduring the period. The weighted average number of shares used to compute diluted net loss per share excludes any assumed issuance of common stock upon exercise of stock options, any assumed issuance of common stock under restricted stock awards andor units, and any assumed issuances under the Company's 2015 Employee Stock Purchase Plan, asemployee stock purchase plan, because the effect, in each case, would be antidilutive. Common stock equivalents of 3.44.8 million and 4.1 million shares for each of the three and nine months ended September 30, 2017,March 31, 2021 and 2.9 million shares for each of the three and nine months ended September 30, 2016,2020, respectively, were excluded from the calculation because of their antidilutive effect.

Out-of-Period Adjustment

In the third quarter of 2016, the Company recorded an adjustment to correct an error in the first quarter of 2016 reported amounts. This resulted in an increase to cost of goods sold by $0.6 million for the three months ended September 30, 2016. The error had the effect of overstating the inventory balance and understating the cost of goods sold, in each case, by $0.6 million for the three months ended March 31, 2016. The adjustment recorded in the third quarter of 2016 corrected the balance sheet

10

SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)

and cost of goods sold for the nine months ended September 30, 2016. The impact to the periods presented and to the previously issued related financial statements was not material.

3. DEBT AND INTEREST

Credit Agreement
In December 2015, the Company entered into a three-yearthree-year credit facility with Wells Fargo Bank, National Association, which was subsequently amended in October 2016, in July 2018, and in July 2020 (as amended, the Credit Facility). The Credit Facility provides an asset-backed revolving line of credit of up to $30.0 million in borrowing capacity with a maturity date of December 24, 2018,July 27, 2021, which maturity date is subject to a one-time, one-yearone-year extension at the Company's election. In addition, under the Credit Facility, at any time through July 27, 2021, the Company may increase the $30.0 million borrowing limit by up to an additional $10.0 million, subject to the Company having sufficient amounts of eligible accounts receivable and inventory and to customary conditions precedent, including obtaining the commitment of lenders to provide such additional amount. In connection with entering into the Credit Facility, the Company was required to become a guarantor and to provide a security interest in substantially all its assets for the benefit of the counterparty.

There were 0 amounts outstanding under the Credit Facility at December 31, 2020. In March 2021, the Company borrowed $20.0 million under the Credit Facility. At March 31, 2021, there was $20.0 million outstanding under the Credit Facility and the Company had $3.2 million of current borrowing capacity under the Credit Facility before the requirement to maintain the minimum fixed charge coverage ratio as discussed below. As of March 31, 2021, the effective interest rate on the amounts borrowed was 4.50%. Debt issuance costs and legal fees related to the Credit Facility totaling $0.6 million were recorded as a deferred asset and are being amortized ratably over the term of the arrangement.
On April 19, 2021, the Company repaid the entire $20.0 million of outstanding borrowings under the Credit Facility.
Borrowings under the Credit Facility accrue interest at the rate then applicable to base rate loans (as customarily defined), unless and until converted into LIBOR rate loans (as customarily defined) in accordance with the terms of the Credit Facility. Borrowings bear interest at a floating annual rate equal to (a) during any month for which the Company's average excess availability (as customarily defined) is greater than $20.0 million, (i) base rate plus 1.25 percentage points for base rate loans and (ii) LIBOR rate plus 2.25 percentage points for LIBOR rate loans, (b) during any month for which the Company's average excess availability is greater than $10.0 million but less than or equal to $20.0 million, (i) base rate plus 1.50 percentage points for base rate loans and (ii) LIBOR rate plus 2.50 percentage points for LIBOR rate loans and (c) during any month for which the Company's average excess availability is less than or equal to $10.0 million, (i) base rate plus 1.75 percentage points for base
11

SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)
rate loans and (ii) LIBOR rate plus 2.75 percentage points for LIBOR rate loans. The Company will also paypays an unused line fee in anbased on the average amount borrowed under the Credit Facility for the most recently completed month. If such average amount is 25% or greater of the maximum borrowing capacity, the unused fee will be equal to 0.375% per annum of the amount unused under the Credit Facility, amount.and if such average amount is less than 25%, the unused line fee will be equal to 0.50% per annum of the amount unused under the Credit Facility. The unused line fee is due and payable on the first day of each month.

In September 2016, the Company borrowed $3.3 million under the Credit Facility. The Company elected to have the LIBOR rate apply to the amount borrowed with an interest period of six months commencing on September 28, 2016, which was further extended for another interest period of six months commencing on March 28, 2017. During the three months ended September 30, 2017, the Company paid off the entire amount borrowed plus accrued interest, totaling $4.1 million. At September 30, 2017, there were no amounts outstanding under the Credit Facility, and the Company had $18.2 million of current borrowing capacity thereunder. Debt issuance costs and legal fees related to the Credit Facility totaling $0.4 million were recorded as a deferred asset and are being amortized ratably over the term of the arrangement.

The Credit Facility contains various customary affirmative and negative covenants, including prohibiting the Company from incurring indebtedness without the lender’s consent. The Credit Facility also includes a financial covenant that requires the Company to maintain a minimum fixed charge coverage ratio of 1.10 to 1.00 for the applicable measurement period, if the Company's Total Liquidity (as defined in the Credit Facility) is less than $5.0 million. The Company was in compliance with all applicable covenants at September 30, 2017.

March 31, 2021.
The Credit Facility also includes customary events of default, including events of default relating to non-payment of amounts due under the Credit Facility, material inaccuracy of representations and warranties, violation of covenants, bankruptcy and insolvency, failure to comply with health care laws, violation of certain of the Company’s existing agreements, and the occurrence of a change of control. Under the Credit Facility, if an event of default occurs, the lender will have the right to terminate the commitments and accelerate the maturity of any loans outstanding.

Insurance Premium Finance Agreements

Paycheck Protection Program
In July 2016,April 2020, due to the Company entered into two insurance premium finance agreements (the Finance Agreements) with First Insurance Funding Corporation and AFCO Acceptance Corporation (the Lenders), under whicheconomic uncertainty resulting from the Lenders agreed to pay premiums, taxes and fees to insurance companiesimpact of the COVID-19 pandemic on the Company's behalfoperations and to support its ongoing operations and retain all employees, the Company applied for various insurance policies. The Company financed an aggregate of $1.2 milliona loan under the Finance Agreements with annual interest rates between 2%Paycheck Protection Program (PPP) of the Coronavirus Aid, Relief, and 4%Economic Security Act (CARES Act). The Company recordedreceived a loan in the total amounts dueoriginal principal amount of $7.2 million. The Company subsequently repaid $1.0 million of the loan. Under the terms of the PPP, subject to specified limitations, the Lenders as short-term debt onloan may be forgiven if the balance sheet. At June 30, 2017,proceeds are used in accordance with the financedCARES Act. The Company used the loan proceeds for purposes consistent with the terms of the PPP and has applied for forgiveness of the entire loan; however, no assurance is provided that the Company will obtain forgiveness of the loan in whole or in part. Any unforgiven portion of the loan is payable over five years at an interest rate of 1%, with a deferral of payments until the date the lender receives the applicable forgiven amount plus accrued interest was paid off and no amounts were outstanding underfrom the Finance Agreements, and no additional amounts have been financed under the Finance Agreements since then.Small Business Association.

11

SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)


4. TRANSACTIONS WITH INTEGRA

Prior to the spin-off, and pursuant to certain supply agreements subsequent to the spin-off, SeaSpine purchased a portion of raw materials and finished goods from Integra for SeaSpine's Mozaik family of products, and SeaSpine contract manufactured certain finished goods for Integra. The Company's purchases of raw materials and Mozaik product finished goods from Integra totaled $0.1 million for each of the three months ended September 30, 2017 and 2016, and $0.4 million and $1.1 million for the nine months ended September 30, 2017 and 2016, respectively. The Company's sale of finished goods sold to Integra under its contract manufacturing arrangement was immaterial for each of the three months ended September 30, 2017 and 2016, and totaled $0.4 million and $0.2 million for the nine months ended September 30, 2017 and 2016, respectively.

Pursuant to a transition services agreement, Integra and SeaSpine provided certain services to one another following the spin-off, and Integra and SeaSpine agreed to indemnify each other against certain liabilities arising from their respective businesses. Under this agreement, Integra provided the Company with certain support functions, including information technology, accounting and other financial functions, regulatory affairs and quality assurance, human resources and other administrative support. The Company incurred no costs under this agreement for either of the three or nine months ended September 30, 2017, an immaterial amount for the three months ended September 30, 2016, and approximately $0.3 million for the nine months ended September 30, 2016.

5. INVENTORIES
Inventories consisted of the following:of:
March 31, 2021December 31, 2020
 (In thousands)
Finished goods$42,074 $37,689 
Work in process11,422 10,087 
Raw materials4,686 6,265 
$58,182 $54,041 

September 30, 2017 December 31, 2016
 (In thousands)
Finished goods$31,182
 $30,922
Work in process8,214
 10,554
Raw materials2,880
 3,823
 $42,276
 $45,299

6.5. PROPERTY, PLANT AND EQUIPMENT
Property, plant and equipment are stated at historical cost less accumulated depreciation and any impairment charges. The Company provides for depreciation using the straight-line method over the estimated useful lives of the assets. Leasehold improvements are amortized over the lesser of the lease term or the useful life. The cost of major additions and improvements is capitalized, while maintenance and repair costs that do not improve or extend the lives of the respective assets are charged to operations as incurred. The cost of computer software obtained for internal use is accounted for in accordance with the Accounting Standards Codification (ASC) 350-40, Internal-Use Software.
The cost of purchased spinal instruments whichthat the Company consigns to hospitals and independent sales agents to support surgeries is initially capitalized as construction in progress. The amount is then either then reclassified to spinal instrumentinstruments and sets, and depreciation is initiated when instruments are put together in a newly built set with spinal implants, or directly expensed for the instruments that are used to replace damaged instruments in an existing set. The depreciation expense and direct expense for replacement instruments are recorded in selling general and administrativemarketing expense.

12

SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)

Property, plant and equipment balances and corresponding useful lives were as follows:
March 31, 2021December 31, 2020Useful Lives
September 30, 2017 December 31, 2016 Useful Lives (In thousands)
(In thousands) 
Leasehold improvement$5,320
 $5,003
 Lease Term
Leasehold improvementsLeasehold improvements$5,990 $5,976 Shorter of lease term or useful life
Machinery and production equipment7,014
 6,826
 3-10 yearsMachinery and production equipment10,007 9,577 3-10years
Spinal instrument sets23,187
 26,618
 5 years
Spinal instruments and setsSpinal instruments and sets34,102 30,275 4-5years
Information systems and hardware7,402
 6,918
 3-7 yearsInformation systems and hardware7,587 7,554 3-7years
Furniture and fixtures1,102
 1,058
 3-5 yearsFurniture and fixtures1,640 1,640 3-5years
Construction in progress7,505
 7,828
 Construction in progress14,254 12,645 
Total51,530
 54,251
  Total73,580 67,667 
Less accumulated depreciation and amortization(29,666) (32,388) Less accumulated depreciation and amortization(37,801)(36,245)
Property, plant and equipment, net$21,864
 $21,863
 Property, plant and equipment, net$35,779 $31,422 
Depreciation and amortization expenses totaled $1.0$1.7 million and $1.1$1.5 million for the three months ended September 30, 2017March 31, 2021 and 2016, respectively, and $3.1 million and $3.4 million for the nine months ended September 30, 2017 and 2016,2020, respectively. The cost of purchased instruments used to replace damaged instruments in existing sets and recorded directly to the instrument replacement expense totaled $0.7 million and $0.4 million and $0.2 million for each of the three months ended September 30, 2017March 31, 2021 and 2016, respectively, and $1.1 million and $1.0 million for the nine months ended September 30, 2017 and 2016,2020, respectively.

For the three and nine months ended September 30, 2016,March 31, 2020, the Company recorded impairment charges to selling and marketing expense totaling $0.2 million and $0.9 million, respectively, against spinal instruments that are no longer expected to be placed into service. NoThere were 0 impairment charges recorded against spinal instruments were recorded for the three or nine months ended September 30, 2017.March 31, 2021.


7.
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SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)
6. IDENTIFIABLE INTANGIBLE ASSETS
Identifiable intangible assets are initially recorded at fair value at the time of acquisition, generally using an income or cost approach. The Company capitalizes costs incurred to renew or extend the term of recognized intangible assets and amortizes those costs over their expected useful lives.
Primarily as a result of an expected shift in future product revenue mix more toward a parallel expanding interbody device based on the Company’s internally developed technology and, in turn, lower future revenue anticipated for the lordotic expanding implant based on technology the Company acquired from N.L.T. Spine Ltd. (NLT) and NLT Spine, Inc., a wholly owned subsidiary of NLT, the Company's estimated future net sales associated with those NLT product technologies decreased. Accordingly, the Company evaluated the ongoing value of the product technology intangible assets associated with the acquisition of these assets. Based on this evaluation, the Company determined that intangible assets with a carrying amount of $1.6 million were no longer recoverable and were impaired, and the Company wrote those intangible assets down to their estimated fair value of $0.3 million at March 31, 2020. Significant estimates used in determining the estimated fair value include measurements estimating cash flows and determining the appropriate discount rate, which are considered Level 3 inputs under Codification 820.
The components of the Company’s identifiable intangible assets were as follows:
were:
September 30, 2017 March 31, 2021
Weighted
Average
Life
 Cost 
Accumulated
Amortization
 Net Weighted
Average
Life
CostAccumulated
Amortization
Net
(Dollars in thousands) (Dollars in thousands)
Product technology12 years $40,769
 $(24,967) $15,802
Product technology12 years33,441 $(30,033)$3,408 
Customer relationships12 years 56,830
 (35,773) 21,057
Customer relationships12 years56,830 $(46,865)9,965 
Trademarks/brand names 300
 (300) 
Trademarks/brand names300 (300)
 $97,899
 $(61,040) $36,859
$90,571 $(77,198)$13,373 

December 31, 2016 December 31, 2020
Weighted
Average
Life
 Cost 
Accumulated
Amortization
 Net Weighted
Average
Life
CostAccumulated
Amortization
Net
(Dollars in thousands) (Dollars in thousands)
Product technology12 years $40,569
 $(22,218) $18,351
Product technology12 years$32,891 $(29,766)$3,125 
Customer relationships12 years 56,830
 (33,396) 23,434
Customer relationships12 years56,830 (46,072)10,758 
Trademarks/brand names 300
 (300) 
Trademarks/brand names300 (300)
 $97,699
 $(55,914) $41,785
$90,021 $(76,138)$13,883 
Annual amortization expense (including amounts reported in cost of goods sold) is expected to be approximately $6.8$4.3 million in 2017, $6.52021, $4.2 million in 2018, $5.82022, $3.5 million in 2019, $4.92023, $1.6 million in 20202024, and $4.9$0.2 million in 2021. Amortization expense totaled $1.7 million and $1.6 million for2025. For each of the three months ended September 30, 2017March 31, 2021 and 2016, respectively,2020, amortization expense totaled $1.1 million and included $0.9$0.3 million and $0.7 million, respectively, of amortization of product technology intangible assets that is presented within cost of goods sold. Amortization expense totaled $5.1 million and $5.6 million forsold in each of the ninethree months ended September 30, 2017March 31, 2021 and

2020.
13
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SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)

7. EQUITY AND STOCK-BASED COMPENSATION
2016, respectively, and included $2.7 million and $2.0 million, respectively, of amortization of product technology intangible assets that is presented within cost of goods sold.

8. BUSINESS COMBINATIONS

Common Stock
In July 2020 and August 2016,2020, the Company entered into an asset purchase agreement with N.L.T Spine Ltd. (NLT),issued 100,100 shares and NLT Spine, Inc., a wholly owned subsidiary of NLT, pursuant to which the Company agreed to purchase certain of the assets of NLT’s medical device business, including substantially all of NLT’s medical device intellectual property related to the ownership, design, development, manufacture, marketing and commercial exploitation of certain expandable interbody devices. The acquisition was undertaken to increase the Company's product offering in expandable interbody devices.

At the initial closing under the asset purchase agreement, the Company entered into (i) an exclusive license agreement with NLT, pursuant to which the Company received an exclusive, worldwide license to make, use, import, offer for sale, sell and otherwise commercially exploit NLT’s expandable interbody device products , (ii) a transition services agreement with NLT, pursuant to which NLT agreed to provide certain services with respect to the continued development of the acquired intellectual property and (iii) a non-competition and non-solicitation agreement with NLT, pursuant to which NLT and its affiliates agreed not to compete with the Company with respect to the acquired intellectual property, subject to certain exceptions.

The purchase price consisted of an initial cash payment to NLT of $1.0 million, which was paid in September 2016 upon the initial closing, and the issuance in January 2017 of 350,000 shares of the Company’s common stock with a total fair value of $2.5 million at issuance as contingent closing consideration upon the satisfaction of certain conditions, including FDA 510(K) clearance of one of the acquired product technologies. In accordance with the terms of the asset purchase agreement, the number of shares issued was determined based on the volume weighted average closing price (VWAP) of the Company's common stock during the 20 trading day period ending one trading day prior to the issuance date, subject to a minimum and maximum VWAP of $10.00 and $17.00, respectively. The VWAP over such 20-trading day period was $7.58 and therefore $10.00 was used.

The Company is also obligated to pay up to a maximum of $5.0 million in milestone payments, payable at the Company's election in cash or in75,585 shares of its common stock which are contingent on the Company's achievement of four independent events related to the commercialization of the acquired product technologies. Additionally, the Company is required to pay royalty payments, in cash, to NLT, equal to declining (over time) percentagesrespectively, as settlement of the Company’s future net sales of certain of the acquired product technologies not to exceed $43.0 million in the aggregate. The Company has the option to terminate any future obligation to make royalty payments by making a one-time cash payment to NLT of $18.0 million.

The Company accounted for this transaction as a business combination in accordance with ASC 805 Business Combinations, and as such, the assets acquired have been recorded at their respective fair values. There were no liabilities assumed. The determination of fair value for the identifiable intangible assets acquired requires extensive use of estimates and judgments. Significant estimates include estimating cash flows and determining the appropriate discount rate, which are considered significant unobservable inputs (Level 3) under the fair value concepts defined in ASC 820. Intangible assets acquired were valued at $9.3 million as of the initial closing date and recorded as product technology intangible assets, which are being amortized ratably over a useful life of 10 years from the initial closing. Acquisition costs of $0.5 million incurred were recorded as selling, marketing and administrative expenses.

The following table summarizes the estimated fair value of total consideration to be paid to NLT as of September 26, 2016, the date of the initial closing. The Company estimated the fair value of the contingent consideration, including contingent milestone payments and contingent royalty payments, using a probability weighted approach that considers the possible outcomes based on assumptions related to the timing and probability of the product launch dates, discount rates matched to the timing of payments, and probability of success rates and discount adjustments on the related cash flows. Subsequent to the acquisition date, at each reporting period, the contingent consideration liabilities will be remeasured at current fair value with changes to be recorded in the consolidated statements of operations. The total purchase price was allocated entirely to product technology intangible asset.
 (In thousands) 
Cash paid for purchase$1,000
Contingent closing consideration2,930
Contingent milestone payments2,310
Contingent royalty payments3,010
Total purchase price$9,250

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SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)


The unaudited pro forma financial information set forth below assumes that the NLT purchased assets had been acquired on January 1, 2016. The unaudited pro forma financial information includes the effect of estimated amortization charges for acquired intangible assets of $0.2 million and $0.6 million for the three and nine months ended September 30, 2016, respectively, and the estimated research and development expenses for the purchased assets of $0.3 million and $0.8 million for the three and nine months ended September 30, 2016, respectively, and excludes the non-recurring acquisition costs of $0.5 million for each of the three and nine months ended September 30, 2016. There was no adjustment to the total revenues. The unaudited pro forma information is presented for informational purposes only and is not indicative of the results of operations that would have been achieved if the acquisition had taken place at the beginning of the periods presented.

The actual amortization charges for acquired intangible assets and research and development expenses for the purchased assets are included in the consolidated statement of operations for the three and nine months ended September 30, 2017, and therefore no adjustment was made to such statement.
 Three Months Ended September 30, Nine Months Ended September 30,
 (In thousands, except per share data)2016 2016
Operating loss$(9,511) $(34,945)
Net loss(9,467) (34,419)
Net loss per share, basic and diluted$(0.84) $(3.07)
Weighted average shares used to compute basic and diluted net loss per share11,271
 11,206


9. FAIR VALUE MEASUREMENTS

The fair values of the Company’s assets and liabilities, including contingent consideration liabilities, are measured at fair value on a recurring basis, and are determined under the fair value categories as follows (in thousands):
  Total Quoted Price in Active Market (Level 1) Significant Other Observable Inputs (Level 2) Significant Unobservable Inputs (Level 3)
September 30, 2017:        
    Contingent consideration liabilities- current $900
 $
 $
 $900
    Contingent consideration liabilities- non-current 3,632
 
 
 3,632
Total contingent consideration $4,532
 $
 $
 $4,532
December 31, 2016:        
    Contingent consideration liabilities- current $2,855
 $
 $
 $2,855
    Contingent consideration liabilities- non-current 5,125
 
 
 5,125
Total contingent consideration $7,980
 $
 $
 $7,980

Contingent consideration liabilities are classified within Level 3 of the fair value hierarchy because they use significant unobservable inputs. For those liabilities, fair value is determined using a probability-weighted discounted cash flow model and significant inputs which are not observable in the market. The significant inputs include assumptions related to the timing and probability of the product launch dates, discount rates matched to the timing of payments, and probability of success rates.

The following table sets forth the changes in the estimated fair value of the Company’s liabilities measured on a recurring basis using significant unobservable inputs (Level 3) for the three and nine months ended September 30, 2017. The gain from change in fair value of contingent closing consideration is the difference between the fair value of shares expected to be issued to NLT based on assumptions as of December 31, 2016, including the forecasted issuance date and stock price, and the fair value of the shares actually issued to NLT on January 31, 2017. The gain from change in fair value of contingent milestone and royalty payments resulted from updated estimated timing of payments, probability of success rates, the passage of time, updated discount rates matched to the estimated timing of payments, actual net sales of certain products for the three and nine months ended September 30, 2017, and lower estimated net sales for the remainder of 2017 and for future royalty payment periods.


15

SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)

Three Months Ended September 30, 2017 (in thousands)
Balance as of June 30, 2017 $5,777
    Contingent consideration liabilities settled (3)
Gain from change in fair value of contingent milestone and royalty payments recorded in selling, general and administrative expenses (1,242)
Fair value at September 30, 2017 $4,532

Nine Months Ended September 30, 2017 (in thousands)
Balance as of January 1, 2017 $7,980
    Contingent consideration liabilities settled (2,551)
    Gain from change in fair value of contingent closing consideration recorded in other income (112)
Gain from change in fair value of contingent milestone and royalty payments recorded in selling, general and administrative expenses (785)
Fair value at September 30, 2017 $4,532


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SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)


10. EQUITY AND STOCK-BASED COMPENSATION

Common Stock

On January 31, 2017, the Company issued 350,000 shares of common stock to NLT as the settlement of contingent closing consideration pursuant to the terms of the asset purchase agreement entered into with NLT in August 2016. The total fair value of such shares was $2.5 million at issuance. See Note 8, "Business Combinations" above.

In August 2016,January 2020, the Company entered into an equity distribution agreement (Distribution Agreement)Underwriting Agreement with Piper JaffraySandler & Co. (Piper Jaffray),and Canaccord Genuity LLC relating to the issuance and sale of 6,800,000 shares of the Company’s common stock at a price to the public of $12.50 per share, before underwriting discounts and commissions. Under the terms of that agreement, the Company granted the underwriters an option, exercisable for 30 days, to purchase up to an additional 1,020,000 shares of common stock. The underwriters exercised this option and the offering closed on January 10, 2020 with the sale of 7,820,000 shares of common stock, resulting in net proceeds to the Company of approximately $92 million, after deducting underwriting discounts and commissions and estimated offering expenses payable by the Company. The offering was made pursuant to which the Company may offer and sell shares of its common stock in “at the market” (ATM) offerings (as defined in Rule 415 of the Securities Act of 1933, as amended) having an aggregate offering price up to $25.0 million in gross proceeds from time to time through Piper Jaffray acting as sales agent. The shares offered and sold under the Distribution Agreement are covered by aCompany’s shelf registration statement on Form S-3 that was declared effective on August 24, 2016. Under the Distribution Agreement, the Company sold 1,500,000 shares of common stock at an average price per share of $10.78 and received net proceeds of approximately $15.6 million (net of $0.6 million of offering costs) during the nine months ended September 30, 2017. The Company intends to use the net proceeds for general corporate purposes, including paying down outstanding borrowings under the Credit Facility, sales and marketing expenditures aimed at growing its business, and research and development expenditures focused on product development. The Company has the capacity to issue additional shares of its common stock to generate up to $8.8 million of gross proceeds under the Distribution Agreement as of September 30, 2017. Future sales, if any, will depend on a variety of factors including, but not limited to, market conditions, the trading price of the Company’s common stock and the Company’s capital needs.

May 22, 2019.
Equity Award Plans

As of June 30, 2015, Integra had stock options, restricted stock awards, performance stock awards, contract stock awards and restricted stock units outstanding under three plans, the 2000 Equity Incentive Plan, the 2001 Equity Incentive Plan, and the 2003 Equity Incentive Plan. In connection with the spin-off, Integra equity awards granted to individuals who became employees of SeaSpine were converted to equity awards denominated in SeaSpine common stock. In general, each post-conversion award is subject to the same terms and conditions as were applicable to the pre-conversion award.
In May 2015, the Company adopted the 2015 Incentive Award Plan, which was subsequently amended and restated with approval of the Company's stockholders. In February and March 2018, the Company's board of directors approved amendments to the plan that increased the share reserve by an aggregate of 2,726,000 shares over the then-existing share reserve thereunder, subject to stockholder approval. The Company's stockholders (asapproved both amendments in May 2018. In April 2020, the Company's board of directors approved an amendment to the plan that, among other things, increased the share reserve by an aggregate of 3,500,000 shares over the then-existing share reserve thereunder, subject to stockholder approval. The Company's stockholders approved the amendment in June 2020 (the 2015 Incentive Award Plan, as amended and restated to date, the 2015Restated Plan). Under the 2015Restated Plan, the Company can grant its employees, and non-employee directors and consultants incentive stock options and non-qualified stock options, restricted stock, performance stock, dividend equivalent rights, stock appreciation rights, stock payment awards and other incentive awards. The Companyaggregate number of shares that may issue upbe issued or transferred pursuant to 3,509,500awards under the Restated Plan is the sum of (1) the number of shares issuable upon exercise or vesting of the equity awards issued by the Company's former parent company prior to the spin-off that were converted into the Company's equity awards under the Restated Plan as of the date of the spin-off and (2) 9,735,500 shares of itsthe Company's common stock in respect of awards granted under the 2015Restated Plan. As of September 30, 2017, thereMarch 31, 2021, 3,023,406 shares were 290,289 shares available to grantfor issuance under the 2015Restated Plan.

In 2016,June 2018, the Company established the 20162018 Employment Inducement Incentive Award Plan (the 20162018 Inducement Plan). The plan is a broad-basedterms of the 2018 Inducement Plan are substantially similar to the terms of the Restated Plan with these principal exceptions: (1) incentive plan which allows for the issuance of stock-based awards, including non-qualified stock options restricted stockmay not be granted under the 2018 Inducement Plan; (2) there are no annual limits on awards performancethat may be issued to an individual under the 2018 Inducement Plan; (3) awards restricted stock unit awards and stock appreciation rights,granted under the 2018 Inducement Plan are not required to be subject to any prospective officer or otherminimum vesting period; and (4) awards may be granted under the 2018 Inducement Plan only to those individuals and in those circumstances described below. An aggregate of 2,000,000 shares are reserved under the 2018 Inducement Plan. As of March 31, 2021, 1,915,623 shares were available for issuance under the 2018 Inducement Plan. As a result of the approval of the amendment to the Restated Plan by the Company's stockholders in June 2020, no awards will be granted under the 2018 Inducement Plan in the future.
In August 2020, the Company adopted the 2020 Employment Inducement Incentive Award Plan (the 2020 Inducement Plan). The terms of the 2020 Inducement Plan are substantially similar to the terms of the 2015 Incentive Award Plan with four principal exceptions: (1) incentive stock options may not be granted under the 2020 Inducement Plan; (2) there are no annual limits on awards that may be issued to an individual under the 2020 Inducement Plan; (3) awards granted under the 2020 Inducement Plan are not required to be subject to any minimum vesting period; and (4) awards may be granted under the 2020 Inducement Plan only to those individuals and in those circumstances described below. An aggregate of 2,000,000 shares are reserved under the 2020 Inducement Plan. As of March 31, 2021, 1,902,288 shares were available for issuance under the 2020 Inducement Plan.
Both the 2018 Inducement Plan and the 2020 Inducement Plan were adopted by the Company’s board of directors without stockholder approval pursuant to Rule 5635(c)(4) of the Nasdaq Listing Rules. In accordance with Rule 5635(c)(4) of the Nasdaq Listing Rules, awards under those plans may only be made to an employee who has not previously been an employee or directormember of SeaSpinethe Company's board of directors or an affiliateof any board of directors of any parent or who is commencing employment with SeaSpinesubsidiary of the Company, or an affiliate following a bona-fidebona fide period of non-employment by SeaSpinethe Company or a parent or subsidiary, if he or she is granted such award in
15

SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)
connection with his or her commencement of employment with the Company or a subsidiary and such grant is an affiliate. An aggregate of 1,000,000 shares are reserved for issuance underinducement material to his or her entering into employment with the 2016 Plan. The Company has not awarded any shares under the 2016 Plan as of September 30, 2017.or such subsidiary.
Restricted Stock Awards and Restricted Stock UnitsForfeiture Rate Assumptions
The Company expenses the fair value of restricted stock awards and of restricted stock units on an accelerated basis over the vesting period or requisite service period, whichever is shorter. Stock-based compensation expense related to restricted stockall equity awards and to restricted stock units includes an estimate for forfeitures. The expected forfeiture rate of all equity-based compensation is based on historical experience of pre-vesting forfeitures on awards and options by each homogenoushomogeneous group of shareowners. For awards and options granted to non-executive employees, the forfeiture rate is estimated to be 15%13% and 14% annually for the ninethree months ended September 30, 2017March 31, 2021 and 12% annually for the nine months ended September 30, 2016.2020, respectively. There is no0 forfeiture rate applied to awards or options granted to non-employee directors or executive employees because their pre-vesting forfeitures are anticipated to be highly unlikely. As individual awards and options become fully vested, stock-based compensation expense is adjusted to recognize actual forfeitures.
Restricted Stock Awards and Restricted Stock Units
Restricted stock award and restricted stock unit grants to employees generally have a requisite service period of three years, and restricted stock award and restricted stock unit grants to non-employee directors generally have a requisite service period of one year. Both are subject to graded vesting. The Company expenses the fair value of restricted stock awards and restricted stock units on an accelerated basis over the vesting period or requisite service period, whichever is shorter.
NaN restricted stock units were granted to non-employee directors during the three months ended March 31, 2021 or 2020. There were no shares of4,021 restricted stock awards granted to non-employee directors during either of the three months ended September 30, 2017 or 2016. There were 120,610 and 75,075 shares ofMarch 31, 2021. NaN restricted stock awards were granted to non-employee

17

SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)

directors during the ninethree months ended September 30, 2017March 31, 2020.
During the three months ended March 31, 2021 and 2016, respectively. There were 34,8002020, 384,585 and 778,755 shares of346,487 restricted stock units were granted to employees, respectively. NaN restricted stock awards were granted to employees during the three and nine months ended September 30, 2017, respectively. Of the total restricted stock units granted to employees, 131,523 shares were issued in lieu of cash bonuses earned under the annual incentive program for corporate and individual performance in 2016. There were no restricted stock units granted during the threeMarch 31, 2021 or nine months ended September 30, 2016. 2020.
As of September 30, 2017,March 31, 2021, there was approximately $3.2$7.5 million of total unrecognized compensation expense related to the unvested portions of restricted stock awards and of restricted stock units. This costexpense is expected to be recognized over a weighted-average period of approximately 1.21.4 years.

Stock Options

Stock option grants to employees generally have a requisite service period of four years, and stock option grants to non-employee directors generally have a requisite service period of one year. Both are subject to graded vesting. The Company records stock-based compensation expense associated with stock options on an accelerated basis over the variousapplicable vesting periodsperiod within each grant and based on their fair value at the date of grant using the Black-Scholes-Merton option pricing model. There were zero533,863 and 43,500681,759 stock options granted during the three months ended September 30, 2017March 31, 2021 and 2016, respectively, and 21,500 and 900,524 stock options granted during the nine months ended September 30, 2017 and 2016,2020, respectively. The following weighted-average assumptions were used in the calculation of fair value for options grants forgranted during the periodsperiod indicated.
 Three Months Ended September 30, Nine Months Ended September 30,Three Months Ended March 31,Three Months Ended March 31,
 2016 2017 201620212020
Expected dividend yield 0% 0% 0%Expected dividend yield0%0%
Risk-free interest rate 1.1% 2.0% 1.3%Risk-free interest rate0.5%1.7%
Expected volatility 38.1% 35.7% 38.3%Expected volatility51.5%45.0%
Expected term (in years) 5.1
 5.1
 4.9
Expected term (in years)5.35.1
The Company considered that it has never paid, and does not currently intend to pay, cash dividends. The risk-free interest rates are derived from the U.S. Treasury yield curve in effect on the date of grant for instruments with a remaining term similar to the expected term of the options. Due to the Company’s limited historical data, theThe expected volatility is calculated based upon the historical volatility of comparable companies in the medical device industry whoseCompany's share prices are publicly available for a sufficient period of time.prices. The expected term of "plain vanilla" options is calculated using the simplified method as prescribed by accounting guidance for stock-based compensation. A "plain vanilla" option is an option with the following characteristics: (1) the option is granted at-the-money; (2) exercisability is conditional only on satisfaction of a service condition through the vesting date; (3) employees who terminate their service prior to vesting forfeit the option; (4) employees who terminate their service after vesting are granted limited time to exercise their options; and (5) the option is nontransferable and non-hedgeable. The expectedhistorical weighted average term of any other option is based on disclosures from similar companies with similar grants. In addition, the Company applies an expected forfeiture rate when amortizing stock-based compensation expense. The expected forfeiture rate of options is based on historical experience of pre-vesting forfeitures on awards by each homogenous group of shareowners. The forfeiture rate of options granted to non-executive employees is estimated to be 15% annually for the nine months ended September 30, 2017, and 12% annually for the nine months ended September 30, 2016. There is no forfeiture rate applied to options granted to non-employee directors or executive employees because their pre-vesting forfeitures are anticipated to be highly unlikely. As individual options become fully vested, stock-based compensation expense is adjusted to recognize actual forfeitures.

Company’s options.
As of September 30, 2017,March 31, 2021, there was approximately $1.2$5.0 million of total unrecognized compensation expense related to unvested stock options. This costexpense is expected to be recognized over a weighted-average period of approximately 1.11.7 years.

1816

SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)

Employee Stock Purchase Plan

In May 2015, the Company adopted the SeaSpine Holdings Corporation 2015 Employee Stock Purchase Plan, which was amended in December 2015November 2018, as described below (as amended, the ESPP). Under the ESPP, eligible employees may purchase shares of the Company’s common stock through payroll deductions of up to 15% of eligible compensation during an offering period. Generally, each offering period will be for a period of twenty-four24 months as determined by the Company's board of directors. There are four six-month purchase periods in each offering period for contributions to be made and to be converted into shares at the end of the purchase period. In no event may an employee purchase more than 2,500 shares per purchase period based on the closing price on the first trading date of an offering period or more than $25,000 worth of stock during any calendar year. The purchase price for shares to be purchased under the ESPP is 85% of the lesser of the market price of the Company's common stock on the first trading date of an offering period or on any purchase date during an offering period (June 30 or December 31).
Subject to stockholder approval, on and effective as of November 2, 2018, the Company's board of directors approved an amendment to the ESPP pursuant to which the share reserve under the ESPP would increase from 400,000 shares to 800,000 shares. The ESPP authorizesCompany's stockholders approved that amendment in May 2019. On December 8, 2020, the Company's board of directors approved the issuance of up to 400,000an additional 500,000 shares of common stock pursuantunder the ESPP, subject to purchase rights granted to employees.stockholder approval. The ESPP is intended to qualify as an “employee stock purchase plan” within the meaning of Section 423 of the Internal Revenue Code of 1986, as amended (the IRC). The first offering period under the ESPP commenced on January 1, 2016 and will end on December 31, 2017. However, the ESPP contains a restart feature, such that if the market price of the stock at the end of any six-month purchase period is lower than the market price at the original grant date of an offering period, that offering period will terminate after that purchase date, and a new two-year offering period will commence on the January 1 or July 1 immediately following the date the original offering period terminated. This restart feature was first triggered on the purchase date that occurred on June 30, 2016,2020, such that the offering period that commenced on January 1, 20162020 was terminated, and a new two-year offering period commenced on July 1, 2016. This restart feature was triggered again on the purchase date that occurred on December 31, 2016, such that the offering period that commenced on July 1, 2016 was terminated, and a new two-year offering period commenced on January 1, 20172020 and will end on December 31, 2018.June 30, 2022. The Company applied share-based payment modification accounting to the awards that were initially valued at the grant date to determine the amount of any incremental fair value associated with the modified awards. The impact to stock-based compensation expense for modifications during the three and nine months ended September 30, 2017March 31, 2021 was immaterial.
During the nine months ended September 30, 2017 and 2016, there were 70,537 and 39,955No shares of common stock respectively,were purchased during the three months ended March 31, 2021 or 2020. The Company recognized $0.3 million and $0.2 million in expense related to the ESPP for the three months ended March 31, 2021 and 2020, respectively. As of March 31, 2021, 127,160 shares were available under the ESPP.

ESPP for future issuance.
The Company estimates the fair value of shares issued to employees under the ESPP using the Black-Scholes-Merton option-pricing model. The following weighted average assumptions were used in the calculation of fair value of shares under the ESPP at the grant date for the periods indicated:
Three Months Ended March 31,
20212020
Expected dividend yield%%
Risk-free interest rate0.1 %1.6 %
Expected volatility64.3 %34.4 %
Expected term (in years)1.21.2
 Three Months Ended September 30, Nine Months Ended September 30,
 2017 2016 2017 2016
Expected dividend yield0% 0% 0% 0%
Risk-free interest rate1.3% 0.5% 1.0% 0.6%
Expected volatility25.3% 29.3% 28.1% 30.5%
Expected term (in years)1.2
 1.2
 1.2
 1.2

11.8. LEASES

The Company determines if an arrangement is a lease at inception. The Company's leases primarily relate to administrative, manufacturing, research, and distribution facilities and various manufacturing, office and transportation equipment through operatingequipment. Lease assets represent the Company's right to use an underlying asset for the lease agreements. Duringterm and lease liabilities represent the nine months ended September 30, 2017,obligation to make lease payments arising from the lease. Lease assets and liabilities are recognized at commencement date based on the present value of lease payments over the lease term. As the Company's leases do not provide an implicit rate, the Company's incremental borrowing rate is used as a discount rate, based on the information available at the commencement date, in determining the present value of lease payments. Lease assets also include the impact of any prepayments made and are reduced by impact of any lease incentives.
The Company made an accounting policy election for short-term leases, such that the Company entered into twowill not recognize a lease agreements: oneliability or lease asset on its balance sheet for leases with a lease term of twelve months or less as of the commencement date. Rather, any short-term lease payments will be recognized as an office located in Wayne, Pennsylvania, whereexpense on a straight-line basis over the Company designs spinal implants and which facilitateslease term. The current period short-term lease expense reasonably reflects the Company's interactions with customers in the Eastern United States, and another for an office located in Lyon, France, which serves as the Company's international sales and marketing office. The terms of these twoshort-term lease agreements are through June 2022 and February 2026, respectively, and both have an average annual cost of less than $0.1 million.


commitments.
19
17

SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)

Future minimumThe Company made a policy election for all classifications of leases to combine lease and non-lease components and to account for them as a single lease component. Variable lease payments underare excluded from the lease liability and recognized in the period in which the obligation is incurred. Additionally, lease terms may include options to extend or terminate the lease when it is reasonably certain the Company will exercise the option.
The Company’s lease portfolio only includes operating leases. As of March 31, 2021, the weighted average remaining lease term of these operating leases was 5.1 years and the weighted average discount rate was 6.5%. For the three months ended March 31, 2021, lease expense, which represents expense from operating leases, was $0.5 million.
A summary of the Company's operating leasesremaining lease liabilities at September 30, 2017March 31, 2021 are as follows:
Operating Leases
(In thousands)
20212,100 
20222,282 
20231,607 
20241,382 
20251,406 
Thereafter1,869 
Total undiscounted value of lease liabilities$10,646 
Less: present value adjustment(1,593)
Less: short-term leases not capitalized(545)
Present value of lease liabilities8,508 
Less: current portion of lease liability(2,159)
Operating lease liability, less current portion$6,349 

 Payments Due by Calendar Year
 (In thousands)
2017$535
20182,082
20192,130
20202,179
20212,221
Thereafter8,474
Total minimum lease payments$17,621

Total lease expense for the three months ended September 30, 2017 and 2016 was $0.5 million and $0.7 million, respectively, and $1.6 million and $2.3 million for the nine months ended September 30, 2017 and 2016, respectively.

12.9. INCOME TAXES
The following table provides a summary ofsummarizes the Company’s effective tax rate for the periods indicated:
 Three Months Ended March 31,
 20212020
Reported income tax expense rate(0.2)%(0.3)%
 Three Months Ended September 30, Nine Months Ended September 30,
 2017 2016 2017 2016
        
Reported tax rate0.8% 1.1% % 1.6%

The Company reported anrecorded a provision for income tax benefitexpense for the three and nine months ended September 30, 2017March 31, 2021 and 2020 primarily related to the release of its ASC 740-10 (Accounting for Uncertainty in Income Taxes) liabilities due to the expiration of the statute of limitations, offset by income tax expenses related to foreign and state operations.

The Company reported an income tax benefit for the three and nine months ended September 30, 2016 which was primarily the result of a refund of tax initially paid toward the income tax return for its U.S. subsidiary which was not part of the U.S consolidated tax group for the tax period January 1, 2015 through August 31, 2015 as well as the release of its ASC 740-10 liabilities due to the expiration of the statute of limitations.

In addition, for all periods presented, the pretax losses incurred by the consolidated U.S. tax group received no corresponding tax benefit because the Company has concluded that it is more likely than not that the Company will be unable to realize the value of any resulting deferred tax assets. The Company will continue to assess its position in future periods to determine if it is appropriate to reduce a portion of its valuation allowance in the future.

On March 27, 2020, Congress enacted the CARES Act to provide certain relief as a result of the COVID-19 pandemic. The CARES Act, among other things, includes provisions relating to net operating loss carryback periods, alternative minimum tax credit refunds, and modification to the net interest deduction limitations. The CARES Act did not have a material impact on the Company's consolidated financial statements for the three months ended March 31, 2021 or 2020.


13.
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SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)
10. COMMITMENTS AND CONTINGENCIES
In consideration for certain technology, manufacturing, distribution, and selling rights and licenses granted to the Company, the Company has agreed to pay royalties on sales of certain products sold by the Company. The royalty payments thatExcept for the royalties paid to NLT, the royalties the Company made under these agreementspaid are included in the consolidated statements of operations as a component of cost of goods sold.sold in the consolidated statements of operations.
The Company is subject to various legal proceedings in the ordinary course of its business with respect to its products, its current or former employees, and its commercial relationships, some of which have been settled by the Company. In the opinion of management, such proceedings are either adequately covered by insurance or otherwise indemnified, or are not expected, individually or in the aggregate, to result in a material adverse effect on the Company's financial condition. However, it is possible that the Company's results of operations, financial position and cash flows in a particular period could be materially affected by these contingencies.
The Company accrues for loss contingencies when it is deemed probable that a loss has been incurred and that loss is estimable. The amounts accrued are based on the full amount of the estimated loss before considering insurance proceeds, and do not include an estimate for legal fees expected to be incurred in connection with the loss contingency. While uncertainty exists, the Company does not believe there are any pending legal proceedings that would have a material impact on the Company’s financial position, cash flows or results of operations.

7D Surgical Acquisition
On March 22, 2021, the Company entered into an arrangement agreement (the Arrangement Agreement) with 7D Surgical Inc., a corporation incorporated under the laws of the Province of Ontario (7D Surgical), Project Maple Leaf Acquisition ULC, an unlimited liability company incorporated under the laws of the Province of British Columbia and wholly owned subsidiary of the Company (Purchaser Sub), and Michael Cadotte and Joel Rose, as the 7D Surgical shareholders’ representatives.
Pursuant to the Arrangement Agreement, Purchaser Sub will acquire all outstanding shares of 7D Surgical, including those 7D Surgical shares issuable upon exercise of outstanding options, and 7D Surgical shall become a wholly owned subsidiary of the Company (the Acquisition). The Acquisition will be effected by way of an arrangement pursuant to the Business Corporations Act (Ontario).

The Company agreed to acquire 7D Surgical for a total purchase price of US$110.0 million, consisting of US$27.5 million in cash and US$82.5 million worth of shares of the Company’s common stock. Canadian-resident 7D Surgical shareholders may elect to receive in lieu of shares of the Company’s common stock, an equivalent number of Class B shares of Purchaser Sub (the Exchangeable Shares), which will be exchangeable on a 1:1 basis for shares of the Company’s common stock, subject to customary adjustments. The Company may require all outstanding Exchangeable Shares to be exchanged upon the occurrence of certain events and at any time following the fifth anniversary of the closing of the Acquisition. While outstanding, holders of Exchangeable Shares will be entitled to receive dividends economically equivalent to the dividends declared by the Company with respect to the Company’s common stock, but will not be entitled to cast votes on matters for which holders of the Company’s common stock are entitled to vote. The aggregate number of shares of the Company’s common stock issuable pursuant to the Acquisition (including upon exchange of Exchangeable Shares) is expected to be 4,289,848, which number of shares was based on the volume-weighted average price for the ten trading day period ending on the date prior to execution of the Arrangement Agreement. The purchase price for the Acquisition is subject to customary adjustments for 7D Surgical’s transaction expenses, cash, indebtedness and working capital.

The Arrangement Agreement contains customary representations, warranties, covenants and agreements of 7D Surgical, Purchaser Sub and the Company. The Acquisition is subject to, among other things, the approval of 7D shareholders at a special meeting expected to be convened by 7D Surgical, receipt of required regulatory and court approvals and third party consents, and other customary closing conditions. Approval of the Acquisition by the Company’s stockholders is not required. The closing of the transactions contemplated by the Arrangement Agreement is anticipated to occur in the second quarter of 2021. The Arrangement Agreement also provides customary termination rights to each of the parties.


20
19

SEASPINE HOLDINGS CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)


14.11. SEGMENT AND GEOGRAPHIC INFORMATION

Segment Reporting
Management assessed its segment reporting based on how it internally manages and reports the results of its business to its chief operating decision maker. Management reviews financial results, manages the business and allocates resources on an aggregate basis. Therefore, financial results are reported in a single operating segment: the development, manufacture and marketing of orthobiologics and of spinal implants. The Company reports revenue in two2 product categories: orthobiologics and spinal implants. Orthobiologics products consist of a broad range of advanced and traditional bone graft substitutes that are designed to improve bone fusion rates following surgery. The spinal implantsimplant portfolio consists of an extensive line of products for minimally invasive surgery, complex spine, deformity and degenerative procedures.
Revenue, net consisted of the following:
 Three Months Ended September 30, Nine Months Ended September 30,
 2017 2016 2017 2016
Orthobiologics$16,333
 $16,186
 $51,073
 $49,649
Spinal implants15,409
 15,555
 46,759
 46,692
Total revenue, net$31,742
 $31,741
 $97,832
 $96,341

The Company attributes revenues to geographic areas based on the location of the customer. Total
The following table disaggregates revenue by major geographic area consistedsales channel for each of the following:periods presented (in thousands):
Three Months Ended March 31, 2021
United StatesInternationalTotal
Orthobiologics$19,060 $2,428 $21,488 
Spinal implants18,410 2,056 20,466 
Total revenue, net$37,470 $4,484 $41,954 
Three Months Ended March 31, 2020
United StatesInternationalTotal
Orthobiologics$17,361 $2,260 $19,621 
Spinal implants14,452 2,038 16,490 
Total revenue, net$31,813 $4,298 $36,111 
20
 Three Months Ended September 30, Nine Months Ended September 30,
 2017 2016 2017 2016
United States$28,245
 $28,485
 $87,209
 $87,041
International3,497
 3,256
 10,623
 9,300
Total revenue, net$31,742
 $31,741
 $97,832
 $96,341


SEASPINE HOLDINGS CORPORATION

NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (continued)
12. SUBSEQUENT EVENTS
In April 2021, the Company entered into an Underwriting Agreement with Piper Sandler & Co., Canaccord Genuity LLC, and Stifel, Nicolaus & Company, Incorporated relating to the issuance and sale of 4,500,000 shares of the Company's common stock at a price to the public of $19.50 per share, before underwriting discounts and commissions. Under the terms of that agreement, the Company granted the underwriters an option, exercisable for 30 days, to purchase up to an additional 675,000 shares of common stock. The underwriters exercised this option and the offering closed on April 20, 2021 with the sale of 5,175,000 shares of common stock, resulting in net proceeds to the Company of approximately $95 million, after deducting underwriting discounts and commissions and estimated offering expenses payable by the Company. The Company used a portion of the net proceeds from the offering to repay all of its outstanding borrowings under the Credit Facility.
21



ITEM 2. MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

The terms “we,” “us,” “our,” “SeaSpine” or the “Company” refer collectively to SeaSpine Holdings Corporation and its wholly-owned subsidiaries, unless otherwise stated. All information presented in this report is based on our fiscal year. Unless otherwise stated, references to particular years, quarters, months or periods refer to our fiscal years ending December 31 and the associated quarters, months and periods of those fiscal years.
This Management’s Discussion and Analysis of Financial Condition and Results of Operations contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended (the Exchange Act). The matters discussed in these forward-looking statements are subject to risk and uncertainties that could cause actual results to differ materially from those made, projected or implied in the forward-looking statements. Such risks and uncertainties may also give rise to future claims and increase exposure to contingent liabilities. Please see the “Risk Factors” section included in our Annual Report on Form 10-K for the year ended December 31, 20162020 (the 20162020 10-K) for a discussion of the uncertainties, risks and assumptions associated with these statements. We undertake no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise.
You can identify these forward-looking statements by forward-looking words such as “believe,” “may,” “could,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “seek,” “plan,” “expect,” “should,” “would” and similar expressions.
These risks and uncertainties arise from (among other factors) the following::

general economic and business conditions, in both domestic and international markets;
our expectations and estimates concerning future financial performance, financing plans and the impact of competition;
our ability to successfully develop new and next-generation products and the costs associated with designing and developing those new and next-generation products, including risks inherent in collaborations, such as with restor3d, Inc. and our pending acquisition of 7D Surgical, or use of nascent manufacturing techniques, such as additive processing/3D printing;
anticipated trends in our business, including healthcare reform in the United States, increased pricing pressure from our competitors or hospitals, exclusion from major healthcare systems, whether as a result of unwillingness to provide required pricing or otherwise, and changes in third-party payment systems;
physicians’ willingness to adopt our recently launched and planned products, customers’ continued willingness to pay for our products and third-party payors’ willingness to provide or continue coverage and appropriate reimbursement for any of our products and our ability to secure regulatory clearance and/or approval for products in development;
our ability to attract and retain new, high-quality distributors, whether as a result of perceived deficiencies, or gaps, in our existing product portfolio, inability to reach agreement on financial or other contractual terms or otherwise, as well as disruption associated with restrictive covenants to, which distributors may be subject and potential litigation and expense associate therewith;
our ability to continue to invest in medical education and training, product development, and/or sales and commercial marketing initiatives at levels sufficient to drive future revenue growth;
anticipated trends in our business, including consolidation among hospital systems, healthcare reform in the United States, increased pricing pressure from our competitors or hospitals, exclusion from major healthcare systems, whether as a result of unwillingness to provide required pricing or otherwise, and changes in third-party payment systems;
the risk of supply shortages, and the associated potentially long-term disruption to product sales, including as a result of the pandemic and of our dependence on PcoMed to supply products incorporating NanoMetalene technology and a limited number of third-party suppliers for components and raw materials and certain processing services;
unexpected expenses and delay and our ability to manage timelines and costs related to manufacturing our products including as a result of litigation or developing and supporting the full commercial launch of new products or relating to the pandemic;
our ability to obtain additional debt and equity financing to fund capital expenditures and working capital requirements and acquisitions;
our ability to complete acquisitions, integrate operations post-acquisition and maintain relationships with customers of acquired entities;

22



our ability to support the safety and efficacy of our products with long-term clinical data;
existing and future regulations affecting our business, both in the United States and internationally, and enforcement of those regulations;
anticipated demand for our products and our ability to purchase or produce our products in sufficient quantities to meet customer demand;

our ability to manage timelines and costs related to manufacturing our products;
our ability to attract and retain new, high-quality independent sales agents, whether as a result of inability to reach agreement on financial or other contractual terms or otherwise, disruption to our existing distribution network as new independent sales agents are added, and the ability of new independent sales agents to generate growth or offset disruption to existing independent sales agents;

our ability to successfully develop new and next-generation products and the costs associated with designing and developing those new and next-generation products;
our ability to support the safety and efficacy of our products with long-term clinical data;
our ability to obtain additional debt and equity financing to fund capital expenditures and working capital requirements and acquisitions;
the risk of supply shortages, including our dependence on a limited number of third-party suppliers for components and raw materials;
our ability to protect our intellectual property, including unpatented trade secrets, and to operate without infringing or misappropriating the proprietary rights of others;

general economic and business conditions, in both domestic and international markets; and

our ability to complete acquisitions, integrate operations post-acquisition and maintain relationships with customers of acquired entities; and
other risk factors described in the section entitled “Risk Factors” of the 20162020 10-K.

These factors should not be construed as exhaustive and should be read in conjunction with the other cautionary statements that are included in this report.
Overview
We are a global medical technology company focused on the design, development and commercialization of surgical solutions for the treatment of patients suffering from spinal disorders. We have a comprehensive portfolio of orthobiologics and spinal implant solutions to meet the varying combinations of products that neurosurgeons and orthopedic spine surgeons need to perform fusion procedures in the lumbar, thoracic and cervical spine. We believe this broad combined portfolio of orthobiologics and spinal implant products is essential to meet the “complete solution” requirements of neurosurgeons and orthopedic spinesuch surgeons.
We report revenue in two product categories: orthobiologics and spinal implants. Our orthobiologics products consist of a broad range of advanced and traditional bone graft substitutes that are designed to improve bone fusion rates following a wide range of orthopedic surgeries, including spine, hip, and extremities procedures. Our spinal implant portfolio consists of an extensive line of products to facilitate spinal fusion in MIS,degenerative, minimally invasive surgery (MIS), and complex spine,spinal deformity and degenerative procedures.
Our U.S. sales organization consists of regional and territory managers who oversee a broad network of independent orthobiologics and spinal implant sales agents. We pay these sales agents to whom we pay commissions based on the sales of our products. Our international sales organization consists of a sales management team that oversees a network of independent orthobiologics and spinal implant stocking sales agentsdistributors that purchase products directly from us and independently sell them. For the ninethree months ended September 30, 2017March 31, 2021 and 2016,2020, international sales accounted for approximately 11% and 10%12% of our revenue, respectively. Our policy is not to sell our products through or to participate in physician-owned distributorships.

For the nine months ended September 30, 2017, our total revenue, net was $97.8 million and our net loss was $24.6 million. For the same period, revenue from sales of orthobiologics and spinal implants totaled $51.0 million and $46.8 million, respectively. We expect to continue to incur losses as we further invest in the expansion of our business, primarily in sales, marketing and research and development related expenditures, and from the general and administrative expenses we expect to incur. As of September 30, 2017, our cash and cash equivalents totaled $16.7 million.

SeaSpine was incorporated in Delaware on February 12, 2015 in connection with the spin-off of the orthobiologics and spinal implant business of Integra. The spin-off occurred on July 1, 2015.

Components of Our Results of Operations
Revenue
Our net revenue is derived primarily from the sale of orthobiologics and spinal implant products across North America, Europe, Asia Pacific and Latin America. Sales are reported net of returns, rebates, group purchasing organization fees and other customer allowances.
In the United States, we generate most of our revenue by consigning our orthobiologics products and by consigning or loaning our spinal implant sets to hospitals and independent sales agents, who in turn either deliver them to hospitals for a single surgical procedure, after which they are returned to us, or leave them with hospitals that are high volume users for multiple procedures. The spinal implant sets typically contain the instruments, disposables, and spinal implants required to complete a surgery. We ship replacement inventory to independent sales agents to replace the consigned inventory used in surgeries. We maintain and replenish loaned sets at our kitting and distribution centers and return replenished sets to a hospital or independent sales agent for the next procedure. We recognize revenue on these consigned or loaned products when they have been used or implanted in a surgical procedure.
For all other sales transactions, including sales to international stocking sales agentsdistributors and private label partners, we generally recognize revenue when the products are shipped toand the customer or stocking sales agent anddistributor obtains control of the transfer of title and risk of loss occurs.


products. There is generally no customer acceptance or other condition that prevents us from recognizing revenue in accordance with the delivery terms for these sales transactions.
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Cost of Goods Sold
Cost of goods sold primarily consists of the costs of finished goods purchased directly from third parties and raw materials used in the manufacturemanufacturing of our products, plant and equipment overhead, labor costs and packaging costs, amortization of product technology intangible assets and freight.costs. The majority of our orthobiologics products are designed and manufactured internally. The cost of human tissue and fixed manufacturing overhead costs are significant drivers of the costscost of goods sold, and consequently our orthobiologics products, at current production volumes, generate lower gross margin than our spinal implant products. We rely on third-party suppliers to manufacture our spinal implant products, and we assemble them into surgical sets at our kitting and distribution centers. BeginningThe cost to inspect incoming finished goods is included in the fourth quartercost of 2016, we began outsourcing a portion of that assembly function to a third party logistics provider.goods sold. Other costs included in cost of goods sold include amortization of product technology intangible assets, royalties, shipping, inspectionscrap and consignment losses, and charges for expired, excess and obsolete inventory. We expect our cost of goods sold to continue to increase in absolute dollars as our sales volume increases over time.
Selling General and AdministrativeMarketing Expense
Our selling general and administrative (SG&A)marketing expenses consist primarily of sales commissions to independent sales agents, cost of medical education and training, payroll and other headcount related expenses, marketing expenses, shipping, third-party logistics expenses, depreciation of instrument sets, instrument replacement expense, stock-based compensation, marketingand cost of medical education and training.
General and Administrative Expense
Our general and administrative expenses supply chainconsist primarily of payroll and distributionother headcount related expenses and expenses for information technology, legal, human resources, insurance, finance, facilities, and management andmanagement. We also record gains or losses associated with changes in the fair value of contingent consideration liabilities.liabilities in general and administrative expenses.
Research and Development Expense
Our research and development (R&D) expenses primarily consist of expenses related to the headcount for engineering, product development, clinical affairs and regulatory functions, as well as consulting services, third-party prototyping services, outside research and clinical studies activities, and materials, production and other costs associated with development of our products. We expense R&D costs as they are incurred.
While our R&D expenses fluctuate from period to period based on the timing of specific initiatives, we expect that these costs will increase over time as we continue to design and commercialize new products and expand our product portfolio, add related personnel and conduct additional clinical activities.
Intangible Amortization
Our intangible amortization, including the amounts reported in cost of goods sold, consists of acquisition-related amortization and impairments related to product discontinuations.amortization. We expect total annual amortization expense (including amounts reported in cost of goods sold) to be approximately $6.8$4.3 million in 2017, $6.52021, $4.2 million in 2018, $5.82022, $3.5 million in 2019, $4.92023, $1.6 million in 20202024 and $4.9$0.2 million in 2021.



RESULTS2025. See “RESULTS OF OPERATIONS
 Three Months Ended September 30, 2017 vs. 2016 Nine Months Ended September 30, 2017 vs. 2016
 (In thousands, except percentages)2017 2016 % Change 2017 2016 % Change
Total revenue, net$31,742
 $31,741
  % $97,832
 $96,341
 1.5 %
Cost of goods sold12,176
 13,881
 (12.3)% 39,342
 42,094
 (6.5)%
Gross profit19,566
 17,860
 9.6 % 58,490
 54,247
 7.8 %
Gross margin61.6% 56.3%   59.8% 56.3% 

Operating expenses:          

Selling, general and administrative23,674
 23,803
 (0.5)% 71,893
 76,166
 (5.6)%
Research and development2,834
 2,600
 9.0 % 9,228
 8,534
 8.1 %
Intangible amortization792
 955
 (17.1)% 2,376
 3,517
 (32.4)%
Total operating expenses27,300
 27,358
 (0.2)% 83,497
 88,217
 (5.4)%
Operating loss(7,734) (9,498) (18.6)% (25,007) (33,970) (26.4)%
Other income (expense), net215
 (59) (464.4)% 387
 (33) (1,272.7)%
Loss before income taxes(7,519) (9,557) (21.3)% (24,620) (34,003) (27.6)%
Benefit for income taxes(57) (103) (44.7)% (12) (559) (97.9)%
Net loss$(7,462) $(9,454) (21.1)% $(24,608) $(33,444) (26.4)%

ThreeOPERATIONS-Three Months Ended September 30, 2017March 31, 2021 Compared to Three Months Ended September 30, 2016March 31, 2020-Impairment of Intangible Assets,” below.
COVID-19 Pandemic - Impact on our Business
The COVID-19 pandemic has presented a substantial public health and economic challenge around the world and has materially and adversely affected our business. We continue to closely monitor developments related to the pandemic and our decisions will continue to be driven by the health and well-being of our employees, our distributor and surgeon customers, and their patients while maintaining operations to support our customers and their patients in the near-term.
Surgery Deferrals: From late March 2020 to mid-May 2020, among other impacts on our business related to the pandemic, surgeons and their patients deferred surgical procedures in which our products otherwise could have been used. This decrease in demand for our products recovered to varying degrees beginning in the latter half of May as local conditions improved in certain geographies that opened after an initial improvement in COVID-19 infection rates, allowing patients to resume receiving their treatments, though demand was below pre-pandemic levels for various periods during 2020 and was below pre-pandemic levels in early 2021. We expect to see continued volatility throughout 2021 and possibly thereafter as geographies respond to current local conditions. The duration of deferrals of surgical procedures, the magnitude of such deferrals, the timing and extent of the economic impact of the pandemic, and the pace at which the economy recovers therefrom, cannot be determined at this time. We continue to work closely with our surgeon customers,
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distributors and suppliers to navigate through this unforeseen event while maintaining flexible operations and investing for future growth.
Operations. Our sales, marketing and research and development efforts have continued since the outbreak of the pandemic, but steps we have taken in response to the pandemic have adversely affected our business. To protect the safety, health and well-being of our employees, distributor and surgeon customers, and communities, we implemented preventative measures including travel restrictions, the temporary closures of certain of our facilities, and requiring all office-based employees to work from home, except for those related to manufacturing, distribution and select others, as permitted under governmental orders. Production at our Irvine orthobiologics manufacturing facility was temporarily halted in April and May 2020 and was restarted in June 2020. The change in the manner in which our workforce is functioning could adversely affect sales and may delay the product launches we plan to make in 2021 and beyond.
Our manufacturing, distribution and supply chain has largely been uninterrupted, but could be disrupted as a result of the pandemic, including because of staffing shortages, production slowdowns, stoppages, or disruptions in delivery systems.
Cost Containment: During 2020, we initiated actions to generate savings in areas such as travel, events, clinical studies, and consulting. We also implemented a temporary freeze on new hires and our senior leadership team voluntarily agreed to a 25% reduction in their base salaries from April 26, 2020 through June 20, 2020.
Product Development: In the early stages of the pandemic, we reduced and/or delayed spending on several planned product development and launch initiatives.We have since increased our spending on product development activities and capital expenditures and inventory for product launches from the reduced levels during the early stages of the pandemic as our revenue and cash flow and demand for our products improved. We continue to evaluate the timing and scope of planned product development and launch initiatives and capital expenditures and inventory growth investments to support those initiatives. Based on that evaluation, we may delay and/or reduce additional spending associated with these initiatives, which may delay the product launches we plan to make in 2021 and beyond, and could adversely affect our future revenue growth or such growth may not be consistent with the timelines we anticipated previously.
Outlook. At this time, the full extent of the impact of the pandemic on our business, financial condition and results of operations is uncertain and cannot be predicted with reasonable accuracy and will depend on future developments that are also uncertain and cannot be predicted with reasonable accuracy.
As of the filing date of this report, the extent to which the pandemic may impact our financial condition or results of operations or guidance is uncertain. The effect of the pandemic will not be fully reflected in our results of operations and overall financial performance until future periods. For additional information on the various risks posed by the pandemic on our business, financial condition and results of operations, please see "Item 1A. Risk Factors" in Part I of the 2020 10-K.
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RESULTS OF OPERATIONS
 Three Months Ended March 31,2021 vs. 2020
 (In thousands, except percentages)20212020% Change
Total revenue, net$41,954 $36,111 16 %
Cost of goods sold15,366 13,812 11 %
Gross profit26,588 22,299 19 %
Gross margin63.4 %61.8 %
Operating expenses:
Selling and marketing23,399 20,476 14 %
General and administrative10,427 8,554 22 %
Research and development4,506 3,895 16 %
Intangible amortization792 792 — %
Impairment of intangible assets— 1,325 (100)%
Total operating expenses39,124 35,042 12 %
Operating loss(12,536)(12,743)(2)%
Other (expense) income, net(159)227 (170)%
Loss before income taxes(12,695)(12,516)%
Provision for income taxes25 35 (29)%
Net loss$(12,720)$(12,551)%

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Three Months Ended March 31, 2021 Compared to Three Months Ended March 31, 2020
Revenue
Total revenue, net for the three months ended September 30, 2017,March 31, 2021, was $31.7$42.0 million, relatively unchangedan increase of 16% compared to the same period in 2016.2020.
Three Months Ended March 31,2021 vs. 2020
20212020% Change
 (In thousands)
Orthobiologics$21,488 $19,621 10 %
United States19,060 17,361 10 %
International2,428 2,260 %
Spinal Implants$20,466 $16,490 24 %
United States18,410 14,452 27 %
International2,056 2,038 %
Total revenue, net$41,954 $36,111 16 %
Three Months Ended March 31,2021 vs. 2020
 Three Months Ended September 30, 2017 vs. 2016 20212020% Change
 2017 2016 % Change (In thousands)
 (In thousands)  
Orthobiologics $16,333
 $16,186
 0.9 %
United States 14,890
 14,593
 2.0 %United States$37,470 $31,813 18 %
International 1,443
 1,593
 (9.4)%International4,484 4,298 %
% of total revenue, net 51% 51%  
      
Spinal Implants $15,409
 $15,555
 (0.9)%
United States 13,355
 13,892
 (3.9)%
International 2,054
 1,663
 23.5 %
% of total revenue, net 49% 49%  
      
Total revenue, net $31,742
 $31,741
  %Total revenue, net$41,954 $36,111 16 %
  Three Months Ended September 30, 2017 vs. 2016
  2017 2016 % Change
  (In thousands)  
United States $28,245
 $28,485
 (0.8)%
International 3,497
 3,256
 7.4 %
Total revenue, net $31,742
 $31,741
  %
Revenue from orthobiologics sales of orthobiologics was $16.3totaled $21.5 million for the three months ended September 30, 2017,March 31, 2021, an increase of $0.1$1.9 million or 0.9%10%, from the same period in 2016.2020. Revenue from sales of our orthobiologics productssales in the United States increased $0.3$1.7 million to $14.9$19.1 million for the three months ended September 30, 2017March 31, 2021 compared to the same period in 2016


and2020. This increase was driven primarily by growth in sales across multiple product lines generated from recently added independent sales agents.higher demand for our fibers-based demineralized bone matrix (DBM) products. Revenue from internationalorthobiologics sales of our orthobiologics products,internationally, which can be volatile from quarter to quarter because of irregular ordering patterns from our stocking sales agents, decreaseddistributors, increased $0.2 million for the three months ended September 30, 2017March 31, 2021 compared to the same period in 2016, which was primarily attributable to decreased sales in Europe.2020.
Revenue from spinal implant sales of spinal implants was $15.4$20.5 million for the three months ended September 30, 2017, a decreaseMarch 31, 2021, an increase of $0.1$4.0 million or 0.9%24%, from the same period in 2016.2020. Revenue from sales of our spinal implant productsimplants sales in the United States decreased $0.5increased $4.0 million to $13.4$18.4 million for the three months ended September 30, 2017March 31, 2021 compared to the same period in 2016, primarily due to lower prices and decreased usage of2020. This increase was driven by higher demand for our legacy systems, which outpaced the revenue growth contributed by recently launched products, andparticularly for those products that were initially or fully launched in 2020. The change in revenue from the impact of the hurricanes in Texas and the Southeast. Revenue from international sales of our spinal implant products, which can be volatile from quarter to quarter because of irregular ordering patterns from our stocking sales agents, increased $0.4 million forinternationally during the three months ended September 30, 2017March 31, 2021 as compared to the same period in 2016, which2020 was primarily attributable to increased sales in Europe.immaterial.
Cost of Goods Sold and Gross Margin
Cost of goods sold decreased $1.7increased $1.6 million, to $12.2$15.4 million for the three months ended September 30, 2017,March 31, 2021, compared to the same period in 2016.2020. Gross margin was 61.6%63.4% for the three months ended September 30, 2017March 31, 2021 and 56.3%61.8% for the same period in 2016.2020. The increase in gross margin was mainly driven bydue primarily to increased sales in the United States of our higher gross margin spinal implant products and lower manufacturing costs for orthobiologics products manufactured at our Irvine, California facility. This was partially offset by a $0.2 million increaseexcess and obsolete inventory provisions in non-cash amortization of technology intangible assets acquired in September 2016 from NLT.relation to revenue.
Cost of goods sold included $0.9 million and $0.7$0.3 million of amortization for product technology intangible assets for each of the three months ended September 30, 2017March 31, 2021 and 2016,2020, respectively.
Selling General and AdministrativeMarketing
SG&ASelling and marketing expenses decreased $0.1increased $2.9 million to $23.7$23.4 million for the three months ended September 30, 2017March 31, 2021 compared to the same period in 2016. This decrease2020. The increase was mainly driven primarily by a $1.2 million non-cash gainhigher distributor commissions, as well as higher selling, customer service, and supply chain headcount and related to a decrease in the fair value of contingent consideration liabilities related to the NLT acquisition (see Note 8, "Business Combinations" to the Notes to Condensed Consolidated Financial Statements included in Part I, Item 1 of this report) and a $1.0 million decrease in consulting and other expenses, due to the completion in late 2016 of the outsourcing project to our third party logistics provider. These decreaseswhich were partially offset by a $1.0decreases in tradeshow and travel costs.
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General and Administrative
General and administrative expenses increased $1.9 million increase in selling commissionsto $10.4 million for the three months ended March 31, 2021, mostly due to $1.3 million of legal and a $1.0 million increase in accrued incentive-based compensationother fees incurred related to our financial performance. While we expect total SG&A expenses for the full year 2017 to decreasepending acquisition of 7D Surgical, as a percentage of revenue compared to the full year 2016, components within SG&A expenses, specifically selling commissions, are expected to increase relative to 2016, both in absolute terms andwell as a percentage of revenue.higher stock-based compensation expense.
Research and Development
R&D expenses increased $0.2$0.6 million to $2.8$4.5 million, or 8.9%11% of revenue, for the three months ended September 30, 2017March 31, 2021 compared to the same period in 2016. The increase was primarily driven by2020 mostly due to higher fees incurred under the transition services agreement with NLT. For the full year 2017, we expect our investment in R&D to be between 8%headcount and 10% of revenue, as we continue to accelerate the design and commercialization of new and next generation products to expand our product portfolio and conduct additional clinical activities.related expenses.
Intangible Amortization
Intangible amortization expense, excluding the amounts reported in cost of goods sold for product technology intangible assets, decreased $0.2remained consistent at $0.8 million to $0.8 millionfor both the three months ended March 31, 2021 and 2020.
Impairment of Intangible Assets
There was no impairment of intangible assets for the three months ended September 30, 2017 comparedMarch 31, 2021. During the three months ended March 31, 2020, impairment of intangible assets was $1.3 million. Primarily as a result of an expected shift in future product revenue mix more toward a parallel expanding interbody device based on our internally developed technology and, in turn, lower future revenue anticipated for the lordotic expanding implant based on technology we acquired from N.L.T. Spine Ltd. (NLT) and NLT Spine, Inc., a wholly owned subsidiary of NLT, our estimated future net sales associated with those NLT Spine product technologies decreased. Accordingly, we evaluated the ongoing value of the product technology intangible assets associated with the acquisition of these assets. Based on this evaluation, we determined that intangible assets with a carrying amount of $1.6 million were no longer recoverable and were impaired, and we wrote those intangible assets down to the same period in 2016. The decrease was primarily due to a customer relationships intangible that was fully amortized by July 2016.


their estimated fair value of $0.3 million.
Income Taxes
Three Months Ended September 30, Three Months Ended March 31,
2017 2016 20212020
(In thousands) (In thousands)
Loss before income taxes$(7,519) $(9,557)Loss before income taxes$(12,695)$(12,516)
Benefit for income taxes(57) (103)
Provision for income taxesProvision for income taxes25 35 
Effective tax rate0.8% 1.1%Effective tax rate(0.2)%(0.3)%
We reported an income tax benefitexpense for the three months ended September 30, 2017March 31, 2021 and 2020 primarily related to the release of our ASC 740-10 liabilities due to the expiration of the statute of limitations, offset by income tax expenses related to our foreign and state operations.

We reported an income tax benefit for the three months ended September 30, 2016 which was primarily the result of a refund of tax initially paid toward the income tax return for our U.S. subsidiary which was not part of the U.S consolidated tax group for the tax period January 1, 2015 through August 31, 2015 as well as the release of our ASC 740-10 liabilities due to the expiration of the statute of limitations.

In addition, for all periods presented, theany pretax losses incurred by the consolidated U.S. tax group, receivedwe recorded no corresponding tax benefit because we have concluded that it is more likely than notmore-likely-than-not that we will be unable to realize the value ofbenefit from any resulting deferred tax assets. We will continue to assess our position in future periods to determine if it is appropriate to reduce a portion of our valuation allowance in the future.

Nine Months Ended September 30, 2017 ComparedIn March 2020, Congress enacted the CARES Act to Nine Months Ended September 30, 2016
Revenue
Total revenue,provide certain relief as a result of the COVID-19 pandemic. The CARES Act, among other things, includes provisions relating to net operating loss carryback periods, alternative minimum tax credit refunds, and modification to the net interest deduction limitations. The CARES Act did not have a material impact on our consolidated financial statements for the ninethree months ended September 30, 2017 increased by $1.5 millionMarch 31, 2021.
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Business Factors Affecting the Results of Operations
Special Charges
We define special charges as expenses for which the amount or timing can vary significantly from period to $97.8 million comparedperiod, and for which the amounts are non-cash in nature, or the amounts are not expected to $96.3 millionrecur at the same magnitude.
We believe that identification of these special charges provides important supplemental information to investors regarding financial and business trends relating to our financial condition and results of operations. Investors may find this information useful in assessing comparability of our operating performance from period to period, against the business model objectives that management has established, and against other companies in our industry. We provide this information to investors so that they can analyze our operating results in the same way that management does and use this information in their assessment of our core business and valuation.
Loss before income taxes includes the following special charges for the same period in 2016.
  Nine Months Ended September 30, 2017 vs. 2016
  2017 2016 % Change
  (In thousands)  
Orthobiologics $51,073
 $49,649
 2.9 %
United States 45,967
 44,411
 3.5 %
International 5,106
 5,238
 (2.5)%
     % of total revenue, net 52% 52%  
       
Spinal Implants $46,759
 $46,692
 0.1 %
United States 41,242
 42,631
 (3.3)%
International 5,517
 4,061
 35.9 %
     % of total revenue, net 48% 48%  
       
Total revenue, net $97,832
 $96,341
 1.5 %
  Nine Months Ended September 30, 2017 vs. 2016
  2017 2016 % Change
  (In thousands)  
United States $87,209
 $87,041
 0.2%
International 10,623
 9,300
 14.2%
Total revenue, net $97,832
 $96,341
 1.5%
Revenue from sales of orthobiologics totaled $51.0 million for the ninethree months ended September 30, 2017, an increaseMarch 31, 2021 and 2020:
Three Months Ended March 31,
20212020
Special Charges:(In thousands)
Impairment of intangible assets(1)
$— $1,325 
Acquisition and integration-related charges for 7D Surgical1,276 — 
Total Special Charges$1,276 $1,325 
(1) Relates to the impairment of $1.4 million or 2.9%, fromacquired product technology intangible assets.
The items reported above are reflected in the same periodconsolidated statements of operations as follows:
Three Months Ended March 31,
20212020
 (In thousands)
Impairment of intangible assets$— $1,325 
General and administrative1,276 — 
Total Special Charges$1,276 $1,325 
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Other Matters
Critical Accounting Policies and the Use of Estimates
Our discussion and analysis of financial condition and results of operations is based upon our consolidated financial statements, which have been prepared in 2016. Revenue from sales of our orthobiologics productsaccordance with accounting principles generally accepted in the United States increased $1.6 millionof America. Preparing these financial statements requires us to $46.0 million formake estimates and assumptions that affect the nine months ended September 30, 2017 compared toreported amounts of assets and liabilities, the same period in 2016disclosure of contingent liabilities, and was driven by growth in sales across multiple product lines generated by recently added independent sales agents.


Revenue from salesthe reported amounts of spinal implants totaled $46.8 million for the nine months ended September 30, 2017, an increase of $0.1 millionrevenues and expenses. Significant estimates affecting amounts reported or 0.1%, from the same period in 2016. Revenue from salesdisclosed in the United States decreased $1.4 million to $41.2 millionconsolidated financial statements include revenue recognition, allowances for the nine months ended September 30, 2017 compared to the same period in 2016, primarily due to lower pricesdoubtful accounts receivable and decreased usagesales return and other credits, net realizable value of our legacy systems, which outpaced the revenue growth contributed by recently launched products. Revenue from international sales of spinal implants increased $1.5 millioninventories, amortization periods for the nine months ended September 30, 2017 compared to the same period in 2016 primarily due to sales by a stocking sales agent we added in Latin America in the third quarter of 2016 and to increased sales in Europe.
Cost of Goods Sold and Gross Margin
Cost of goods sold decreased $2.8 million, to $39.3 million for the nine months ended September 30, 2017, compared to the same period in 2016. Gross margin was 59.8% for the nine months ended September 30, 2017, compared to 56.3% for the same period in 2016. The increase in gross margin was mainly driven by lower manufacturing costs for orthobiologics products manufactured at our Irvine, California facility, and by a $1.7 million provision for excess orthobiologics raw material inventory recorded in the first quarter of 2016. This provision related to management's decision to repurpose a portion of our matched-donor bone raw material for other production uses and that rendered a large portion of the remaining and now unmatched-donor bone as excess quantities that were unlikely to be consumed in future production. These improvements were partially offset by a $0.7 million increase in non-cash amortization of technologyacquired intangible assets, acquired in September 2016 from NLT.
Costestimates of goods sold included $2.7 millionprojected cash flows and $2.0 million of amortization for product technologydiscount rates used to value intangible assets and test them for the nine months ended September 30, 2017impairment, estimates of projected cash flows and 2016, respectively.
Selling, General and Administrative
SG&A expenses decreased $4.3 million to $71.9 million for the nine months ended September 30, 2017 compared to the same period in 2016. The decrease was mainly driven by a $3.1 million decrease in consulting and other expensesassumptions related to the completion in late 2016 of various significant information system related projectstiming and probability of the projectproduct launch dates, discount rates matched to outsource a large portionthe timing of our spinal implant kittingpayments, and distributionprobability of success rates used to a third party logistics provider, $1.2 million lower legal fees, the absence of a $0.9 million spinal instrument impairment charge recorded in 2016, and a $0.8 million non-cash gain related to a decrease in the fair value of contingent consideration liabilities relatedfrom business combinations, estimates of projected cash flows and depreciation and amortization periods for long-lived assets, valuation of stock-based compensation, computation of taxes and valuation allowances recorded against deferred tax assets, and loss contingencies. These estimates are based on historical experience and on various other assumptions believed to the NLT acquisition. These decreases were partially offset by a $2.0 million increase in selling commissions.
Research and Development
R&D expenses increased $0.7 million to $9.2 million, or 9.4% of revenue, for the nine months ended September 30, 2017 compared to the same period in 2016. The increase was primarily driven by higher external costs related to product development related to our orthobiologics products, and by fees incurredbe reasonable under the transition services agreement with NLT.current circumstances. Actual results could differ from these estimates.
Intangible Amortization
Intangible amortization expense, excludingThe full extent to which the amounts reported in costCOVID-19 pandemic will directly or indirectly impact our business, results of goods sold for product technology intangible assets, decreased $1.1 million to $2.4 million for the nine months ended September 30, 2017 compared to the same period in 2016. The decrease was primarily due tooperations and financial condition, including sales, expenses, manufacturing, research and development costs and employee-related compensation, will depend on future developments that are highly uncertain, including as a customer relationships intangible that was fully amortized by July 2016.

Income Taxes
 Nine Months Ended September 30,
 2017 2016
 (In thousands)
Loss before income taxes$(24,620) $(34,003)
Benefit for income taxes(12) (559)
Effective tax rate% 1.6%

We reported an income tax benefit for the nine months ended September 30, 2017 primarily related to the release of our ASC 740-10 liabilities due to the expiration of the statute of limitations, offset by income tax expenses related to our foreign and state operations.



We reported an income tax benefit for the nine months ended September 30, 2016 which was primarily the result of a refundgenetic variations of, tax initially paid towardor other information that may emerge concerning, COVID-19 and the income tax return for our U.S. subsidiary which was not part of the U.S consolidated tax group for the tax period January 1, 2015 through August 31, 2015actions taken to contain it or treat COVID-19, as well as the releaseeconomic impact on local, regional, national and international customers and markets. We have made estimates of the impact of COVID-19 within our financial statements and there may be changes to those estimates in future periods. Actual results may differ from these estimates.
Note 2, “Summary of Significant Accounting Policies” to the Notes to Unaudited Condensed Consolidated Financial Statements included in Part I, Item 1 of this report and included in Part II, Item 8 of the 2020 10-K describe the significant accounting policies and estimates used in the preparation of our ASC 740-10 liabilities due condensed consolidated financial statements.
Recently Issued Accounting Pronouncements
Information regarding new accounting pronouncements is included in Note 2, "Summary of Significant Accounting Policies,"to the expirationNotes to Unaudited Condensed Consolidated Financial Statements included in Part I, Item 1 of the statute of limitations.this report.

In addition, for all periods presented, the pretax losses incurred by the consolidated U.S. tax group received no corresponding tax benefit because we have concluded that it is more likely than not that we will be unable to realize the value of any resulting deferred tax assets.



Liquidity and Capital Resources
Overview,

Capital Resources, and Capital Requirements
As of September 30, 2017,March 31, 2021, we had cash and cash equivalents and investments totaling approximately $16.7$87.7 million, and $18.2$3.2 million of current borrowing capacity was available under our credit facility. We believe that our cash and cash equivalents, on handincluding the net proceeds from the underwritten offering completed in April 2021, and the amount currently available to us under our credit facility, will be sufficient to fund our operations and meet our contractual obligations for at least the next twelve months.

Paycheck Protection Program Loan
In April 2020, due to the economic uncertainty resulting from the impact of the COVID-19 pandemic on our operations and to support our ongoing operations and retain all employees, we applied for a loan under the Paycheck Protection Program (PPP) of the Coronavirus Aid, Relief, and Economic Security Act (CARES Act). We received a loan in the original principal amount of $7.2 million. We subsequently repaid $1.0 million of the loan. Under the terms of the PPP, subject to specified limitations, the loan may be forgiven if the proceeds are used in accordance with the CARES Act. In October 2020, we applied for forgiveness of the entire loan. As of April 30, 2021, we have not learned the extent to which our loan will be forgiven. Any unforgiven portion of the loan is payable over five years at an interest rate of 1%, with a deferral of payments until the date the lender receives the applicable forgiven amount from the SBA. No assurance is provided that we will obtain forgiveness of the loan in whole or in part.
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Credit Facility

We have a $30.0 million credit facility with Wells Fargo Bank, National Association which expiresmatures in December 2018,July 2021, subject to a one-time, one-year extension at our election. In addition, at any time through July 27, 2021, we may increase the borrowing limit by up to an additional $10.0 million, subject to us having sufficient amounts of eligible accounts receivable and inventory and to customary conditions precedent, including obtaining the commitment of lenders to provide such additional amount. At September 30, 2017,March 31, 2021, we had no$20.0 million outstanding borrowings under the credit facility. The borrowing capacity under the credit facility is determined monthly and is based on the amount of our eligible accounts receivable and inventory balances and qualified cash (as defined in the credit facility). Depending on the extent to which our eligible accounts receivable and inventory balances increase, our borrowing capacity could increase by as much as an additional $8.3$3.3 million from the $18.2$3.2 million available as of September 30, 2017March 31, 2021 before we are required to maintain the minimum fixed charge coverage ratio as discussed below. The credit facility contains various customary affirmative and negative covenants, including prohibiting us from incurring indebtedness without the lender’s consent. In April 2020, we received the lender’s consent to obtain the PPP loan. Under the terms of the credit facility, if our Total Liquidity (as defined in the credit facility) is less than $5.0 million, we are required to maintain a minimum fixed charge coverage ratio of 1.10 to 1.00 for the applicable measurement period. Our Total Liquidity was $34.2$88.4 million at September 30, 2017,March 31, 2021, and therefore that financial covenant was not applicable at that time.

On April 19, 2021, we repaid the entire $20.0 million of outstanding borrowings under the credit facility.
Business Combinations

Underwritten Offering
In August 2016,January 2020, we entered into an asset purchase agreementUnderwriting Agreement with NLT to acquire certain of the assets of NLT’s medical device business relatedPiper Sandler & Co. and Canaccord Genuity LLC relating to the expandable interbody medical devices. We made an up-front cash paymentissuance and sale of $1.0 million in connection with the initial closing in September 2016 and issued 350,000 shares of our common stock in January 2017 as contingent closing consideration. At September 30, 2017, we recorded a $2.5 million liability representing the estimated fair value of future contingent milestone payments related to the achievement of certain commercial milestones, which we anticipate will become payable at varying times between 2018 and 2023, and a $2.0 million liability representing the estimated fair value of future contingent royalty payments based on percentages of our future net sales of certain of the products and technology we acquired, which we anticipate will become payable at varying times between 2017 and 2028. The contingent milestone payments, if any, are payable in cash or in6,800,000 shares of our common stock at our election.a public offering price of $12.50 per share, before underwriting discounts and commissions. We granted the underwriters an option, exercisable for 30 days, to purchase up to an additional 1,020,000 shares of common stock. The contingent royalty payments, if any, are payable in cash.

At The Market Program

In August 2016, we entered into an equity distribution agreementunderwriters exercised this option and the offering closed on January 10, 2020 with Piper Jaffray & Co. (Piper Jaffray), pursuant to which we may offer and sellthe sale of 7,820,000 shares of our common stock, resulting in “at the market” (ATM) offerings (as defined in Rule 415 of the Securities Act of 1933, as amended) having an aggregate offering price up to $25.0 million in gross proceeds from time to time through Piper Jaffray acting as sales agent. During the nine months ended September 30, 2017, we received net proceeds of approximately $15.6$92 million, net of $0.6 million ofafter deducting underwriting discounts and commissions and estimated offering costs, fromexpenses payable by us.
In April 2021, we entered into an Underwriting Agreement with Piper Sandler & Co., Canaccord Genuity LLC, and Stifel, Nicolaus & Company, Incorporated relating to the issuance and sale of 1,500,000 shares of our common stock. We have the capacity to issue additional4,500,000 shares of our common stock at a price to generatethe public of $19.50 per share, before underwriting discounts and commissions. Under the terms of that agreement, we granted the Underwriters an option, exercisable for 30 days, to purchase up to $8.8 millionan additional 675,000 shares of gross proceeds undercommon stock. The underwriters exercised this option and the equity distribution agreement asoffering closed on April 20, 2021 with the sale of September 30, 2017. Future sales, if any, will depend on a variety5,175,000 shares of factors including, but not limited to, market conditions, the trading price of our common stock, resulting in net proceeds of approximately $95 million, after deducting underwriting discounts and our capital needs.commissions and estimated offering expenses payable us.



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Cash and Cash Equivalents
We had cash and cash equivalents totaling approximately $16.7$87.7 million and $14.6$76.8 million at September 30, 2017March 31, 2021 and December 31, 2016,2020, respectively.
Cash Flows
Nine Months Ended September 30, 2017 vs. 2016 Three Months Ended March 31,2021 vs. 2020
2017 2016 % Change 20212020% Change
(In thousands)   (In thousands)
Net cash used in operating activities$(4,109) $(10,406) (60.5)%Net cash used in operating activities$(2,958)$(2,710)%
Net cash used in investing activities(5,718) (6,857) (16.6)%Net cash used in investing activities(4,100)(28,053)(85)%
Net cash provided by financing activities11,532
 4,455
 158.9 %Net cash provided by financing activities18,059 90,636 (80)%
Effect of exchange rate changes on cash and cash equivalents418
 187
 123.5 %Effect of exchange rate changes on cash and cash equivalents(65)(66)(2)%
Net decrease in cash and cash equivalents$2,123
 $(12,621) (116.8)%
Net change in cash and cash equivalentsNet change in cash and cash equivalents$10,936 $59,807 (82)%
Net Cash Used in Operating Activities
CashNet cash used in operating activities for the ninethree months ended September 30, 2017 decreasedMarch 31, 2021 increased by $6.3$0.2 million compared to the same period in 2016 primarily due to lower cash-based operating expenses incurred and lower purchases of inventory in the nine months ended September 30, 2017 compared to the same period in 2016, partially offset by lower cash collections in the nine months ended September 30, 2017 compared to the same period in 2016.2020.
Net Cash Used in Investing ActivitiesActivities
Net cash used in investing activities was $5.7 million for the ninethree months ended September 30, 2017March 31, 2021 decreased by $24.0 million compared to $6.9 million for the same period in 2016.2020. The decrease was primarily due to larger$25.0 million of investments in leasehold improvementsU.S. Treasury Bills during the three months ended March 31, 2020 compared to 0 such investments for the same period in our Carlsbad facility2021, partially offset by a $1.6 million increase in purchases of property and equipment during the first half of 2016 andthree months ended March 31, 2021 compared to the $1.0 million cash payment associated with the NLT acquisition during the third quarter of 2016, offset by more instrument purchasessame period in 2017 to support recent spinal implant product launches.2020.
Net Cash Provided by Financing Activities
Net cash provided by financing activities was $11.5$18.1 million for the ninethree months ended September 30, 2017 andMarch 31, 2021. Cash provided by financing activities in 2021 was comprised primarily of $15.6$20.0 million of net proceeds from the sale of shares of our common stockborrowed under the ATM equity offering programCredit Facility and $0.5 million of proceeds from the saleexercise of shares of our common stock under our 2015 Employee Stock Purchase Plan. We used $4.0options, offset by $2.4 million of cash used for tax payments we made on our employees' behalf for shares we withheld from such employees on the vesting of restricted stock awards to repay allcover statutory tax withholding requirements. Net cash provided by financing activities was $90.6 million for the three months ended March 31, 2020. It was comprised primarily of the outstanding borrowings under the credit facility and $0.4$91.6 million proceeds from issuance of common stock, net of offering costs, offset by $1.9 million of cash used for tax payments we made on our employees' behalf for shares we withheld from such employees on the vesting of restricted stock awards to repay the remaining short-term debt related to our insurance premium finance agreements (see Note 3, "Debt and Interest" to the Notes to Condensed Consolidated Financial Statements included in Part I, Item 1 of this report).cover statutory tax withholding requirements.
Off-Balance Sheet Arrangements
There were no off-balance sheet arrangements as of September 30, 2017March 31, 2021 that have, or are reasonably likely to have, a current or future effect on our financial condition, changes in financial condition, revenues or expenses, results of operations, cash flows, liquidity, capital expenditures or capital resources that is material to our business.

Contractual Obligations and Commitments

ThereWith the exception of our obligations under the arrangement agreement with 7D Surgical Inc., there have been no material changes outside the ordinary course of our business to the contractual obligations disclosed in the 20162020 10-K.
Information regarding the arrangement agreement with 7D Surgical Inc. is included in

Other Matters
Critical Accounting PoliciesNote 10, "Commitments and the Use of Estimates

Our discussion and analysis of financial condition and results of operations is based upon our consolidated financial statements, which have been prepared in accordance with GAAP. The preparation of these financial statements requires us to make estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent liabilities, and the reported amounts of revenues and expenses. Significant estimates affecting amounts reported or disclosed in the consolidated financial statements include revenue recognition, allowances for doubtful accounts receivable and sales return and


other credits, net realizable value of inventories, amortization periods for acquired intangible assets, estimates of projected cash flows and discount rates used to value intangible assets and test them for impairment, estimates of projected cash flows and assumptions related to the timing and probability of the product launch dates, discount rates matched to the estimated timing of payments, and probability of success rates used to value contingent consideration liabilities from business combinations, estimates of projected cash flows and depreciation and amortization periods for long-lived assets, valuation of stock-based compensation, computation of taxes and valuation allowances recorded against deferred tax assets, and loss contingencies. These estimates are based on historical experience and on various other assumptions that are believed to be reasonable under the current circumstances. Actual results could differ from these estimates.

ContingenciesNote 2, “Summary of Significant Accounting Policies”," to the Notes to Condensed Consolidated Financial Statements included in Part I, Item 1 of this report and included in Part II, Item 8 of the 2016 10-K describe the significant accounting policies and estimates used in the preparation of our condensed consolidated financial statements. Those policies and estimates disclosed in the 2016 10-K have not materially changed.
Recently Issued Accounting Pronouncements
Information regarding new accounting pronouncements is included in Note 2, "Summary of Significant Accounting Policies,"to the Notes to Unaudited Condensed Consolidated Financial Statements included in Part I, Item 1 of this report.

ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK
The market risk exposures described in Part II,As a "smaller reporting company" as defined by Item 7A10 of Regulation S-K, the 2016 10-K haveCompany is not materially changed duringrequired to provide the nine months ended September 30, 2017.information required by this item.    
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ITEM 4. CONTROLS AND PROCEDURES
Evaluation of Disclosure Controls and Procedures
Based on an evaluation under the supervision and with the participation of our management, our Chief Executive Officer and Chief Financial Officer have concluded that our disclosure controls and procedures as defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act were effective as of the end of the period covered by this report to ensure that information required to be disclosed by us in reports that we file or submit under the Exchange Act is (i) recorded, processed, summarized and reported within the time periods specified in the SEC rules and forms and (ii) accumulated and communicated to our management, including our Chief Executive Officer and Chief Financial Officer, as appropriate to allow timely decisions regarding required disclosure.
Changes in Internal Control over Financial Reporting

There have been no changes in our internal control over financial reporting identified in connection with the evaluation required by Rules 13a-15(d) and 15d-15(d) under the Exchange Act that occurred during the fiscal quarter to which this report relates that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.
Inherent Limitations of Internal Controls

Our management, including our Chief Executive Officer and Chief Financial Officer, does not expect that our disclosure controls and procedures or our internal controls over financial reporting will prevent or detect all error and all fraud. A control system, no matter how well designed and operated, can provide only reasonable, not absolute, assurance that the objectives of the control system are met. Because of the inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within the Company have been detected. These inherent limitations include the realities that judgments in decision-making can be faulty, and that breakdowns can occur because of a simple error or mistake. Additionally, controls can be circumvented by the individual acts of some persons, by collusion of two or more people, or by management override of the controls. The design of any system of controls also is based in part upon certain assumptions about the likelihood of future events, and there can be no assurance that any design will succeed in achieving its stated goals under all potential future conditions. Over time, controls may become inadequate because of changes in conditions, or the degree of compliance with the policies or procedures may deteriorate. Because of the inherent limitations in a cost-effective control system, misstatements due to error or fraud may occur and not be detected.

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PART II. OTHER INFORMATION

ITEM 1. LEGAL PROCEEDINGS

From time to time, we are subject to legal proceedings and claims in the ordinary course of business. While management presently believes that the ultimate outcome of these proceedings, individually and in the aggregate, will not materially harm our financial position, cash flows, or overall trends in results of operations, in part because of the insurance policies we maintain that cover certain of these claims, legal proceedings are subject to inherent uncertainties, and unfavorable rulings or outcomes could occur that have individually or in the aggregate, a material adverse effect on our business, financial condition or operating results. We are not currently subject to any pending material legal proceedings,litigation, other than ordinary routine proceedingslitigation incidental to our business, as described above.

ITEM 1A. RISK FACTORS
TheSee "Item 1A. Risk Factors" in Part I of the 2020 10-K for a detailed discussion of the risks we face. Except as set forth below, the risk factors described in the 20162020 10-K have not materially changed.

Risks Related to our Pending Acquisition of 7D Surgical Inc.

The pending acquisition of 7D Surgical Inc. (7D Surgical) may present many risks and we may not realize the strategic and financial goals that were contemplated at the time we entered into the arrangement agreement with 7D Surgical on March 22, 2021 (the Arrangement Agreement).


Pursuant to the Arrangement Agreement, subject to the satisfaction or waiver of specified closing conditions, we will acquire all outstanding shares of 7D Surgical, including those 7D Surgical shares issuable upon exercise of outstanding options, and 7D Surgical will become our wholly owned subsidiary (the Acquisition).

Risks we may face in connection with the Acquisition and subsequent integration of 7D Surgical include:
We may not realize the benefits we expect to receive from the Acquisition, such as a best-in-class enabling technology that provides surgeons a radiation-free navigational system that integrates seamlessly into the surgical workflow; gaining access to new accounts and/or increasing our presence in existing accounts by providing access to the 7D Surgical technology and/or placing systems at little or no upfront cost to the hospital through product earn-outs; expanding applications for the 7D Surgical offering, such as in minimally invasive procedures; and the ability of the 7D Surgical technology to position us to address the full patient continuum of care, from pre-operative imaging and surgical planning to post-operative plan confirmation and predictive analytics.
The Acquisition may not further our business strategy as we expect, we may not successfully integrate 7D Surgical as planned, there could be unanticipated adverse impacts on our or 7D Surgical’s business, and/or we may otherwise not realize the expected return on our investment, which could adversely affect our business or operating results and potentially cause impairment to assets that we record as a part of the Acquisition, including intangible assets and goodwill.
Our operating results or financial condition may be adversely impacted by (i) claims or liabilities related to 7D Surgical’s business arising after closing; (ii) unfavorable accounting treatment as a result of 7D Surgical’s practices; and/or (iii) intellectual property claims or disputes.
7D Surgical was not required to maintain an internal control infrastructure that would meet the standards of a U.S. public company, including the requirements of the Sarbanes-Oxley Act of 2002. The costs that we may incur to implement such controls and procedures may be substantial and we could encounter unexpected delays and challenges in this implementation. In addition, we may discover significant deficiencies or material weaknesses in the quality of 7D Surgical’s financial and disclosure controls and procedures.         
We may fail to identify or assess the magnitude of certain liabilities, shortcomings or other circumstances prior to acquiring 7D Surgical, which could result in unexpected litigation or regulatory exposure, unfavorable accounting treatment, a diversion of management’s attention and resources, and other adverse effects on our business, financial condition, and operating results.
The closing of the Acquisition could be delayed or not consummated, including in the event that closing conditions (such as the receipt of required regulatory approvals) are not satisfied or waived or we or 7D Surgical terminate the Arrangement Agreement.
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The occurrence of any of these risks could have a material adverse effect on our business, financial condition, and operating results.
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ITEM 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS

Recent Sales of Unregistered Securities
None.During the first quarter of 2021, we did not issue any securities that were not registered under the Securities Act of 1933, as amended (the Securities Act).
Purchases of Equity Securities by the Issuer
The table below is a summary of purchases of our common stock we made during the quarter covered by this report. Other than as indicated in the table below, no such purchases were made in any other month during the quarter. We do not have any publicly announced repurchase plans or programs.
Period Total Number of Shares Purchased (1)
 Average Price Paid per Share
 Total Number of Shares Purchased as Part of Publicly Announced Plans or Programs
 Maximum Number of Shares That May Yet be Purchased Under the Plans or Programs
PeriodTotal Number of Shares Purchased (1)Average Price Paid per ShareTotal Number of Shares Purchased as Part of Publicly Announced Plans or ProgramsMaximum Number of Shares That May Yet be Purchased Under the Plans or Programs
        
September 1- September 30 171
 $10.39
 
 
January 1 - January 31January 1 - January 31134,856 $17.45 — — 
February 1 - February 28February 1 - February 281,829 $16.77 — — 
March 1 - March 31March 1 - March 311,642 $19.02 — — 
(1)These shares were surrendered to the Company to satisfy tax withholdings obligations in connection with the vesting of restricted stock awards.


ITEM 3. DEFAULTS UPON SENIOR SECURITIES

Not applicable.



ITEM 4. MINE SAFETY DISCLOSURES

Not applicable.

ITEM 5. OTHER INFORMATION

None.
None
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ITEM 6. EXHIBITS

Exhibit No.Description
10.1*
Exhibit No.10.2**#Description
*31.1
10.3*(1)
31.1**
31.2**31.2
32.1***32.1
32.2***32.2
*101.INS*101.INSInline XBRL Instance Document – the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document.
*101.SCH*101.SCHInline XBRL Taxonomy Extension Schema Document
*101.CAL*101.CALInline XBRL Taxonomy Extension Calculation Linkbase Document
*101.DEF*101.DEFInline XBRL Definition Linkbase Document
*101.LAB*101.LABInline XBRL Taxonomy Extension Labels Linkbase Document
*101.PRE*101.PREInline XBRL Taxonomy Extension Presentation Linkbase Document
104Cover Page Interactive Data File (embedded within Exhibit 101.INS Inline XBRL document)

*#Management compensatory contract or plan.
*Portions of this exhibit have been redacted in compliance with Regulation S-K Item 601(b)(10). The redacted information is not material and would likely cause competitive harm to the registrant if publicly disclosed.
**Filed herewith
***
These certifications are being furnished solely to accompany this report pursuant to 18 U.S.C. 1350, and are not being

filed for purposes of Section 18 of the Securities Exchange Act of 1934 and are not to be incorporated by reference into any filing of the registrant, whether made before or after the date hereof, regardless of any general incorporation by reference language in such filing.
(1)Incorporated by reference from the registrant's current report of Form 8-K filed on March 24, 2021.

† The financial information of SeaSpine Holdings Corporation Quarterly Report on Form 10-Q for the quarter ended September 30, 2017March 31, 2021 filed on November 2, 2017May 3, 2021 formatted in XBRL (ExtensibleiXBRL (Inline Extensible Business Reporting Language): (i) the Condensed Consolidated Statements of Operations, (ii) Condensed Consolidated Statements of Comprehensive Loss, (iii) the Condensed Consolidated Balance Sheets, (iv) Parenthetical Data to the Condensed Consolidated Balance Sheets, (v) the Condensed Consolidated Statements of Cash Flows, (vi) the Condensed Consolidated StatementStatements of
37



Equity, and (vii) Notes to Unaudited Condensed Consolidated Financial Statements, is furnished electronically herewith.

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SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
SEASPINE HOLDINGS CORPORATION
Date:November 2, 2017May 3, 2021/s/ Keith C. Valentine
Keith C. Valentine
President and Chief Executive Officer
(Principal Executive Officer)
Date:November 2, 2017
Date:May 3, 2021/s/ John J. Bostjancic
John J. Bostjancic
Chief Financial Officer
(Principal Financial Officer)

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