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Perceptive Advisors

Filed: 15 Nov 21, 4:30pm

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number:3235-0006
Expires:Oct 31, 2018
Estimated average burden
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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
1LIFE HEALTHCARE INCCOM68269G10710,780532,350SH SOLE 532,35000
4D MOLECULAR THERAPEUTICS INCOM35104E10010,121375,256SH SOLE 375,25600
ABSCI CORPORATIONCOM00091E10917,1751,476,776SH SOLE 1,476,77600
ACCOLADE INCCOM00437E10211,798279,774SH SOLE 279,77400
ACHILLES THERAPEUTICS PLCSPONSORED ADS00449L1025,884755,375SH SOLE 755,37500
ACLARIS THERAPEUTICS INCCOM00461U10514,062781,236SH SOLE 781,23600
ADAPTIVE BIOTECHNOLOGIES CORCOM00650F10911,992352,804SH SOLE 352,80400
ADMA BIOLOGICS INCCOM00089910414,98613,262,375SH SOLE 13,262,37500
AGILE THERAPEUTICS INCCOM00847L10015,30115,919,925SH SOLE 15,919,92500
ALBIREO PHARMA INCCOM01345P10673,6362,360,139SH SOLE 2,360,13900
ALDEYRA THERAPEUTICS INCCOM01438T10686,9569,903,879SH SOLE 9,903,87900
ALPHATEC HLDGS INCCOM NEW02081G2015,252430,900SH SOLE 430,90000
AMICUS THERAPEUTICS INCCOM03152W109253,64326,559,443SH SOLE 26,559,44300
APELLIS PHARMACEUTICALS INCCOM03753U10620,270615,000SH SOLE 615,00000
ASTRIA THERAPEUTICS INCCOM04635X10217,3231,959,652SH SOLE 1,959,65200
ATEA PHARMACEUTICALS INCCOM04683R10679,2082,259,224SH SOLE 2,259,22400
ATHENEX INCCOM04685N10340,73313,532,467SH SOLE 13,532,46700
ATHIRA PHARMA INCCOM04746L10432,1353,425,916SH SOLE 3,425,91600
AVIDITY BIOSCIENCES INCCOM05370A10821,818885,818SH SOLE 885,81800
AXSOME THERAPEUTICS INCCOM05464T1042,65180,420SH SOLE 80,42000
BCLS ACQUISITION CORPCOM CL AG0904B1059,9601,000,000SH SOLE 1,000,00000
BEAM THERAPEUTICS INCCOM07373V10546,780537,635SH SOLE 537,63500
BIOATLA INCCOM09077B10425,025850,026SH SOLE 850,02600
BIOGEN INCCOM09062X10313,75348,600SH SOLE 48,60000
BRIDGEBIO PHARMA INCCOM10806X102363,5677,756,928SH SOLE 7,756,92800
BUTTERFLY NETWORK INC*W EXP 02/12/202124155110642233,333SH SOLE 233,33300
C4 THERAPEUTICS INCCOM STK12529R107100,9132,258,566SH SOLE 2,258,56600
CAREMAX INCCOM CL A14171W10332,6993,385,000SH SOLE 3,385,00000
CAREMAX INC*W EXP 06/08/20214171W11117060,000SH SOLE 60,00000
CASSAVA SCIENCES INCCOM14817C1076,208100,000SHPutSOLE 100,00000
CELLDEX THERAPEUTICS INC NEWCOM NEW15117B20221,251393,613SH SOLE 393,61300
CEREVEL THERAPEUTICS HLDNG ICOM15678U128152,6885,175,867SH SOLE 5,175,86700
CHEMOCENTRYX INCCOM16383L1069,405550,000SH SOLE 550,00000
CHEMOCENTRYX INCCOM16383L10615,786923,200SHCallSOLE 923,20000
CLOVER HEALTH INVESTMENTS COCOM CL A18914F10311,0851,500,000SH SOLE 1,500,00000
CM LIFE SCIENCES III INCUNIT 04/30/202812584120512,8131,250,000SH SOLE 1,250,00000
CODEX DNA INCCOM1920031014,730425,000SH SOLE 425,00000
COGENT BIOSCIENCES INCCOM19240Q20126,8173,188,750SH SOLE 3,188,75000
COHERUS BIOSCIENCES INCCOM19249H10376,8054,779,387SH SOLE 4,779,38700
COHERUS BIOSCIENCES INCNOTE 1.500% 4/119249HAB949,3654,500,000PRN SOLE 4,500,00000
COLLEGIUM PHARMACEUTICAL INCNOTE 2.625% 2/119459JAA2180,25017,500,000PRN SOLE 17,500,00000
CONCERT PHARMACEUTICALS INCCOM2060221057,0332,150,641SH SOLE 2,150,64100
CRINETICS PHARMACEUTICALS INCOM22663K10783,4323,963,517SH SOLE 3,963,51700
CUE HEALTH INCCOM22979010018,6671,580,607SH SOLE 1,580,60700
DA32 LIFE SCNCE TEC ACQSTN CCLASS A COM23312M1064,915500,000SH SOLE 500,00000
DARIOHEALTH CORPCOM NEW23725P2094,475327,869SH SOLE 327,86900
DAY ONE BIOPHARMACEUTICALS ICOM23954D10913,195556,047SH SOLE 556,04700
DBV TECHNOLOGIES S ASPONSORED ADR23306J10137,7087,695,505SH SOLE 7,695,50500
EIGER BIOPHARMACEUTICALS INCCOM28249U105934139,890SH SOLE 139,89000
ESTABLISHMENT LABS HLDGS INCCOMG3124910836,186505,541SH SOLE 505,54100
FERRARI N VCOMN3167Y1031,2976,200SH SOLE 6,20000
FREQUENCY THERAPEUTICS INCCOM35803L1081,569222,222SH SOLE 222,22200
FULCRUM THERAPEUTICS INCCOM3596161098,297294,118SH SOLE 294,11800
FUSION PHARMACEUTICALS INCCOM36118A1009,9361,254,607SH SOLE 1,254,60700
GLOBAL BLOOD THERAPEUTICS INCOM37890U108112,3004,407,399SH SOLE 4,407,39900
GRAPHITE BIO INCCOM38870X10414,343875,093SH SOLE 875,09300
HARMONY BIOSCIENCES HLDGS INCOM41319710418,833491,332SH SOLE 491,33200
HEALTH CATALYST INCCOM42225T10729,456589,004SH SOLE 589,00400
HEALTH SCIENCES ACQ CORP 2ORD SHSG4411D1094,451450,000SH SOLE 450,00000
HEALTHCOR CATALIO ACQU CORPCL A SHSG4412510514,8501,500,000SH SOLE 1,500,00000
HORIZON THERAPEUTICS PUB LSHSG46188101214,3631,956,940SH SOLE 1,956,94000
ICOSAVAX INCCOM45114M10956,8881,922,549SH SOLE 1,922,54900
IMAGO BIOSCIENCES INCCOM45250K1072,504125,000SH SOLE 125,00000
IMMATICS N.VSHSN4444510932,5002,500,000SH SOLE 2,500,00000
IMMUNEERING CORPCLASS A COM45254E10718,082681,051SH SOLE 681,05100
IMMUNOCORE HLDGS PLCADS45258D10514,828400,000SH SOLE 400,00000
INHIBRX INCCOM45720L10737,3571,121,490SH SOLE 1,121,49000
INSULET CORPCOM45784P10112,65444,522SH SOLE 44,52200
INVITAE CORPCOM46185L103111,5513,923,741SH SOLE 3,923,74100
IOVANCE BIOTHERAPEUTICS INCCOM462260100283,33711,489,772SH SOLE 11,489,77200
IVERIC BIO INCCOM46583P102121,3427,471,798SH SOLE 7,471,79800
KODIAK SCIENCES INCCOM50015M10944,271461,248SH SOLE 461,24800
KRONOS BIO INCCOM50107A10450,7472,421,142SH SOLE 2,421,14200
KYMERA THERAPEUTICS INCCOM50157510410,573180,000SH SOLE 180,00000
LANDOS BIOPHARMA INCCOM515069102217,10114,869,915SH SOLE 14,869,91500
LEAP THERAPEUTICS INCCOM52187K10133,9908,476,496SH SOLE 8,476,49600
LIFESCI ACQUISITION II CORPCOM53229E1032,940300,000SH SOLE 300,00000
LYRA THERAPEUTICS INCCOM55234L10529,4033,222,560SH SOLE 3,222,56000
MACROGENICS INCCOM55609910944,9802,148,060SH SOLE 2,148,06000
MEIRAGTX HLDGS PLCCOMG5966510291,5786,948,277SH SOLE 6,948,27700
MIRATI THERAPEUTICS INCCOM60468T105599,3263,387,745SH SOLE 3,387,74500
MORPHIC HLDG INCCOM61775R10550,259887,340SH SOLE 887,34000
MOTUS GI HLDGS INCCOM62014P1081,2421,800,542SH SOLE 1,800,54200
NANOBIOTIX SASPONSORED ADS63009J10712,0391,059,800SH SOLE 1,059,80000
NANOSTRING TECHNOLOGIES INCNOTE 2.625% 3/063009RAD112,7991,000,000PRN SOLE 1,000,00000
NATERA INCCOM63230710417,830160,000SH SOLE 160,00000
NAUTILUS BIOTECHNOLOGY INCCOM63909J10854,7148,911,151SH SOLE 8,911,15100
NEPTUNE WELLNESS SOLUTIONS ICOM64079L1056,08010,055,521SH SOLE 10,055,52100
NEUROCRINE BIOSCIENCES INCCOM64125C10946,325483,007SH SOLE 483,00700
NEVRO CORPCOM64157F10330,256259,972SH SOLE 259,97200
NEVRO CORPNOTE 2.750% 4/064157FAC7126,2349,000,000PRN SOLE 9,000,00000
NUVALENT INCCOM67070310716,913750,000SH SOLE 750,00000
NUVATION BIO INCCOM CL A67080N10130,2283,041,004SH SOLE 3,041,00400
ONCORUS INCCOM68236R10310,2721,099,810SH SOLE 1,099,81000
OUTSET MED INCCOM69014510798,4171,990,633SH SOLE 1,990,63300
PHARVARIS N VCOMN6960510847927,000SH SOLE 27,00000
PMV PHARMACEUTICALS INCCOM69353Y1038,991301,714SH SOLE 301,71400
POINT BIOPHARMA GLOBAL INCCOM7305411099,5571,242,879SH SOLE 1,242,87900
POSEIDA THERAPEUTICS INCCOM73730P1085,743787,745SH SOLE 787,74500
PROCEPT BIOROBOTICS CORPCOM74276L10563,2141,656,990SH SOLE 1,656,99000
PROMETHEUS BIOSCIENCES INCCOM74349U10878,5763,314,032SH SOLE 3,314,03200
PROTARA THERAPEUTICS INCCOM STK74365U1072,918421,641SH SOLE 421,64100
PROTHENA CORP PLCSHSG728001087,123100,000SH SOLE 100,00000
PROVENTION BIO INCCOM74374N1026,070948,481SH SOLE 948,48100
QUOTIENT LTDSHSG7326810737,91016,200,818SH SOLE 16,200,81800
RAIN THERAPEUTICS INCCOM75082Q10537,9542,537,019SH SOLE 2,537,01900
RAPID MICRO BIOSYSTEMS INCCLASS A COM75340L1046,465350,000SH SOLE 350,00000
RAPT THERAPEUTICS INCCOM75382E10990,2802,907,565SH SOLE 2,907,56500
REGENXBIO INCCOM75901B1073,74389,283SH SOLE 89,28300
RELAY THERAPEUTICS INCCOM75943R10261,2661,943,097SH SOLE 1,943,09700
RESEARCH ALLIANCE CORP IICOM CL A7608731099,8501,000,000SH SOLE 1,000,00000
ROCKET PHARMACEUTICALS INCCOM77313F10669,0542,310,261SH SOLE 2,310,26100
ROCKLEY PHOTONICS HOLDINGS L*W EXP 08/11/202G7614L1171,195500,000SH SOLE 500,00000
SEMA4 HOLDINGS CORPCOM CL A81663L10118,9752,500,000SH SOLE 2,500,00000
SIGHT SCIENCES INCCOM82657M1058,853390,000SH SOLE 390,00000
SINGULAR GENOMICS SYSTEMS INCOM82933R10034,3963,073,824SH SOLE 3,073,82400
SOLID BIOSCIENCES INCCOM83422E10532,05613,412,552SH SOLE 13,412,55200
SOMALOGIC INCCLASS A COM83444K10525,4002,050,000SH SOLE 2,050,00000
SOMALOGIC INC*W EXP 03/01/20283444K113380110,000SH SOLE 110,00000
SPRINGWORKS THERAPEUTICS INCCOM85205L107307,6784,849,912SH SOLE 4,849,91200
SUMMIT HEALTHCRE ACQUISTN COUNIT 06/03/2026G8566R12810,0501,000,000SH SOLE 1,000,00000
SURROZEN INCCOM86889P1093,540500,000SH SOLE 500,00000
SURROZEN INC*W EXP 08/01/20386889P117190166,666SH SOLE 166,66600
TARSUS PHARMACEUTICALS INCCOM87650L10327,9371,296,416SH SOLE 1,296,41600
TAYSHA GENE THERAPIES INCCOM SHS8776191065,967320,440SH SOLE 320,44000
TRAVERE THERAPEUTICS INCNOTE 2.500% 9/1761299AB2454,82445,000,000PRN SOLE 45,000,00000
TRAVERE THERAPEUTICS INCCOM89422G10747,6651,965,555SH SOLE 1,965,55500
TREACE MED CONCEPTS INCCOM89455T10933,2451,235,886SH SOLE 1,235,88600
TYRA BIOSCIENCES INCCOM90240B10617,370987,500SH SOLE 987,50000
UNITED THERAPEUTICS CORP DELCOM91307C10226,155141,700SH SOLE 141,70000
VBI VACCINES INC CDACOM NEW91822J103171,18255,042,465SH SOLE 55,042,46500
VERONA PHARMA PLCSPONSORED ADS92505010615,8312,888,889SH SOLE 2,888,88900
VERRICA PHARMACEUTICALS INCCOM92511W10845,1303,610,412SH SOLE 3,610,41200
VERU INCCOM92536C10337,9704,451,342SH SOLE 4,451,34200
VIATRIS INCCOM92556V10613,6101,004,419SH SOLE 1,004,41900
VIRIDIAN THERAPEUTICS INCCOM92790C10423,4081,423,000SH SOLE 1,423,00000
VYNE THERAPEUTICS INCCOM92941V2093,2392,330,471SH SOLE 2,330,47100
XENON PHARMACEUTICALS INCCOM98420N10530,8972,022,051SH SOLE 2,022,05100
ZYMERGEN INCCOM98985X10011,633883,332SH SOLE 883,33200
ZYMEWORKS INCCOM98985W102106,8633,679,845SH SOLE 3,679,84500