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Perceptive Advisors

Filed: 14 Feb 22, 4:05pm

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number:3235-0006
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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
1LIFE HEALTHCARE INCCOM68269G1079,353532,350SH SOLE 532,35000
ABSCI CORPORATIONCOM00091E10911,5771,411,776SH SOLE 1,411,77600
ACADIA PHARMACEUTICALS INCCOM00422510836,9721,584,052SH SOLE 1,584,05200
ACCOLADE INCCOM00437E1026,030228,774SH SOLE 228,77400
ACHILLES THERAPEUTICS PLCSPONSORED ADS00449L1023,784755,375SH SOLE 755,37500
ACLARIS THERAPEUTICS INCCOM00461U10511,359781,236SH SOLE 781,23600
ADAPTIVE BIOTECHNOLOGIES CORCOM00650F1099,900352,804SH SOLE 352,80400
ADMA BIOLOGICS INCCOM00089910416,82611,933,387SH SOLE 11,933,38700
AGILE THERAPEUTICS INCCOM00847L10010,39421,294,485SH SOLE 21,294,48500
ALBIREO PHARMA INCCOM01345P10654,9682,360,139SH SOLE 2,360,13900
ALDEYRA THERAPEUTICS INCCOM01438T10639,6169,903,879SH SOLE 9,903,87900
AMICUS THERAPEUTICS INCCOM03152W109306,76226,559,443SH SOLE 26,559,44300
APELLIS PHARMACEUTICALS INCCOM03753U10668,6361,451,700SH SOLE 1,451,70000
ARENA PHARMACEUTICALS INCCOM NEW04004760746,470500,000SH SOLE 500,00000
ASTRIA THERAPEUTICS INCCOM04635X10210,5621,959,652SH SOLE 1,959,65200
ATHENEX INCCOM04685N10318,40413,532,467SH SOLE 13,532,46700
ATHIRA PHARMA INCCOM04746L10444,6403,425,916SH SOLE 3,425,91600
AXSOME THERAPEUTICS INCCOM05464T1043,03880,420SH SOLE 80,42000
BCLS ACQUISITION CORPCOM CL AG0904B1059,8001,000,000SH SOLE 1,000,00000
BELLUS HEALTH INC NEWCOM NEW07987C20461,5447,645,234SH SOLE 7,645,23400
BIOATLA INCCOM09077B10412,979661,200SH SOLE 661,20000
BIOGEN INCCOM09062X10311,66048,600SH SOLE 48,60000
BIOMARIN PHARMACEUTICAL INCCOM09061G101104,2531,180,000SH SOLE 1,180,00000
BRIDGEBIO PHARMA INCCOM10806X102118,9077,128,755SH SOLE 7,128,75500
BUTTERFLY NETWORK INC*W EXP 02/12/202124155110296233,333SH SOLE 233,33300
C4 THERAPEUTICS INCCOM STK12529R10771,1262,208,913SH SOLE 2,208,91300
CAREMAX INCCOM CL A14171W10327,2603,549,525SH SOLE 3,549,52500
CAREMAX INC*W EXP 06/08/20214171W1118460,000SH SOLE 60,00000
CASSAVA SCIENCES INCCOM14817C10713,110300,000SHPutSOLE 300,00000
CELLDEX THERAPEUTICS INC NEWCOM NEW15117B2028,880229,807SH SOLE 229,80700
CEREVEL THERAPEUTICS HLDNG ICOM15678U128164,9115,086,727SH SOLE 5,086,72700
CHEMOCENTRYX INCCOM16383L10651,5361,415,446SH SOLE 1,415,44600
CLOVER HEALTH INVESTMENTS COCOM CL A18914F1035,5801,500,000SH SOLE 1,500,00000
CODEX DNA INCCOM1920031014,590425,000SH SOLE 425,00000
COGENT BIOSCIENCES INCCOM19240Q20127,3593,188,750SH SOLE 3,188,75000
COHERUS BIOSCIENCES INCCOM19249H10386,3085,407,798SH SOLE 5,407,79800
COHERUS BIOSCIENCES INCNOTE 1.500% 4/119249HAB951,4894,500,000PRN SOLE 4,500,00000
COLLEGIUM PHARMACEUTICAL INCNOTE 2.625% 2/119459JAA2169,31317,500,000PRN SOLE 17,500,00000
CONCERT PHARMACEUTICALS INCCOM2060221056,7742,150,641SH SOLE 2,150,64100
CRINETICS PHARMACEUTICALS INCOM22663K107146,6965,163,517SH SOLE 5,163,51700
CRYOLIFE INCCOM2289031006,641326,318SH SOLE 326,31800
CUE HEALTH INCCOM22979010021,1961,580,607SH SOLE 1,580,60700
DA32 LIFE SCNCE TEC ACQSTN CCLASS A COM23312M1064,905500,000SH SOLE 500,00000
DARIOHEALTH CORPCOM NEW23725P2094,252327,869SH SOLE 327,86900
DAY ONE BIOPHARMACEUTICALS ICOM23954D1099,369556,047SH SOLE 556,04700
DECIPHERA PHARMACEUTICALS INCOM24344T1011,954200,000SHCallSOLE 200,00000
DICE THERAPEUTICS INCCOM23345J10417,841704,885SH SOLE 704,88500
EIGER BIOPHARMACEUTICALS INCCOM28249U105726139,890SH SOLE 139,89000
ENVVENO MEDICAL CORPORATIONCOM29415J1065,150781,615SH SOLE 781,61500
EQRX INCCOM26886C1078,5251,250,000SH SOLE 1,250,00000
EQRX INC*W EXP 12/17/20226886C115266250,000SH SOLE 250,00000
ESTABLISHMENT LABS HLDGS INCCOMG3124910827,411405,541SH SOLE 405,54100
FERRARI N VCOMN3167Y1031,6056,200SH SOLE 6,20000
FULCRUM THERAPEUTICS INCCOM3596161095,203294,118SH SOLE 294,11800
FUSION PHARMACEUTICALS INCCOM36118A1005,1171,227,017SH SOLE 1,227,01700
GLOBAL BLOOD THERAPEUTICS INCOM37890U108100,9793,449,915SH SOLE 3,449,91500
GRAPHITE BIO INCCOM38870X10410,567850,093SH SOLE 850,09300
HARMONY BIOSCIENCES HLDGS INCOM41319710410,202239,258SH SOLE 239,25800
HEALTH CATALYST INCCOM42225T10717,988454,004SH SOLE 454,00400
HEALTH SCIENCES ACQ CORP 2ORD SHSG4411D1094,536450,000SH SOLE 450,00000
HORIZON THERAPEUTICS PUB LSHSG46188101187,3011,738,140SH SOLE 1,738,14000
HYPERFINE INCCOM CL A44916K10610,8751,500,000SH SOLE 1,500,00000
ICOSAVAX INCCOM45114M10943,6211,906,548SH SOLE 1,906,54800
IMMATICS N.VSHSN4444510933,6002,500,000SH SOLE 2,500,00000
IMMUNEERING CORPCLASS A COM45254E10711,013681,051SH SOLE 681,05100
IMMUNOCORE HLDGS PLCADS45258D10512,326360,000SH SOLE 360,00000
INHIBRX INCCOM45720L10758,6701,343,490SH SOLE 1,343,49000
INVITAE CORPCOM46185L10324,1971,584,585SH SOLE 1,584,58500
IOVANCE BIOTHERAPEUTICS INCCOM462260100193,34210,127,941SH SOLE 10,127,94100
ISOPLEXIS CORPCOM46500510637,6374,095,498SH SOLE 4,095,49800
ITEOS THERAPEUTICS INCCOM46565G10493120,000SH SOLE 20,00000
IVERIC BIO INCCOM46583P102108,3466,480,000SH SOLE 6,480,00000
KODIAK SCIENCES INCCOM50015M10944,098520,152SH SOLE 520,15200
KRONOS BIO INCCOM50107A10432,9032,421,142SH SOLE 2,421,14200
KYMERA THERAPEUTICS INCCOM5015751049,841155,000SH SOLE 155,00000
LANDOS BIOPHARMA INCCOM51506910271,37514,869,915SH SOLE 14,869,91500
LEAP THERAPEUTICS INCCOM52187K10127,4638,476,496SH SOLE 8,476,49600
LEGEND BIOTECH CORPSPONSORED ADS52490G1028,814189,100SH SOLE 189,10000
LIANBIOSPONSORED ADS53000N108346,93156,319,960SH SOLE 56,319,96000
LYRA THERAPEUTICS INCCOM55234L10514,0503,222,560SH SOLE 3,222,56000
MACROGENICS INCCOM55609910926,7271,665,243SH SOLE 1,665,24300
MADRIGAL PHARMACEUTICALS INCCOM5588681057,32286,400SH SOLE 86,40000
MEIRAGTX HLDGS PLCCOMG59665102164,9526,948,277SH SOLE 6,948,27700
MERUS N VCOMN5749R10011,130350,000SH SOLE 350,00000
MINERVA SURGICAL INCCOM60343F10645187,768SH SOLE 87,76800
MIRATI THERAPEUTICS INCCOM60468T105481,6983,283,783SH SOLE 3,283,78300
MORPHIC HLDG INCCOM61775R10539,634836,521SH SOLE 836,52100
MOTUS GI HLDGS INCCOM62014P1088411,800,542SH SOLE 1,800,54200
NANOBIOTIX SASPONSORED ADS63009J1078,5841,059,800SH SOLE 1,059,80000
NANOSTRING TECHNOLOGIES INCNOTE 2.625% 3/063009RAD111,9831,000,000PRN SOLE 1,000,00000
NAUTILUS BIOTECHNOLOGY INCCOM63909J10847,1959,111,151SH SOLE 9,111,15100
NEPTUNE WELLNESS SOLUTIONS ICOM64079L1054,12310,055,521SH SOLE 10,055,52100
NEUROCRINE BIOSCIENCES INCCOM64125C10941,138483,007SH SOLE 483,00700
NEVRO CORPCOM64157F1031,86022,946SH SOLE 22,94600
NEVRO CORPNOTE 2.750% 4/064157FAC7101,5209,000,000PRN SOLE 9,000,00000
NUVALENT INCCOM67070310714,280750,000SH SOLE 750,00000
NUVATION BIO INCCOM CL A67080N10124,8262,920,823SH SOLE 2,920,82300
ONCORUS INCCOM68236R1035,269999,812SH SOLE 999,81200
OUTSET MED INCCOM69014510785,8841,863,397SH SOLE 1,863,39700
PHARVARIS N VCOMN6960510838927,000SH SOLE 27,00000
PMV PHARMACEUTICALS INCCOM69353Y1032,888125,000SH SOLE 125,00000
POINT BIOPHARMA GLOBAL INCCOM7305411096,6861,193,995SH SOLE 1,193,99500
PROCEPT BIOROBOTICS CORPCOM74276L10533,2201,328,285SH SOLE 1,328,28500
PROMETHEUS BIOSCIENCES INCCOM74349U108125,4523,172,785SH SOLE 3,172,78500
PROTARA THERAPEUTICS INCCOM STK74365U1072,846421,641SH SOLE 421,64100
PROTHENA CORP PLCSHSG728001084,940100,000SH SOLE 100,00000
PROVENTION BIO INCCOM74374N1025,330948,481SH SOLE 948,48100
PULMONX CORPCOM74584810124,447762,304SH SOLE 762,30400
PYXIS ONCOLOGY INCCOMMON STOCK74732410121,3261,944,114SH SOLE 1,944,11400
QUOTIENT LTDSHSG7326810741,96016,200,818SH SOLE 16,200,81800
RAIN THERAPEUTICS INCCOM75082Q10531,9892,483,619SH SOLE 2,483,61900
RAPID MICRO BIOSYSTEMS INCCLASS A COM75340L1044,104385,693SH SOLE 385,69300
RAPT THERAPEUTICS INCCOM75382E109107,5292,927,565SH SOLE 2,927,56500
RELAY THERAPEUTICS INCCOM75943R10259,6721,943,097SH SOLE 1,943,09700
RESEARCH ALLIANCE CORP IICOM CL A7608731099,7701,000,000SH SOLE 1,000,00000
ROCKET PHARMACEUTICALS INCCOM77313F10642,7681,959,125SH SOLE 1,959,12500
ROCKLEY PHOTONICS HOLDINGS L*W EXP 08/11/202G7614L117605500,000SH SOLE 500,00000
SCIENCE 37 HOLDINGS INCCOM80864410818,7051,500,000SH SOLE 1,500,00000
SEMA4 HOLDINGS CORPCOM CL A81663L10111,1502,500,000SH SOLE 2,500,00000
SIGHT SCIENCES INCCOM82657M1056,852390,000SH SOLE 390,00000
SINGULAR GENOMICS SYSTEMS INCOM82933R10038,5393,333,824SH SOLE 3,333,82400
SOLID BIOSCIENCES INCCOM83422E10523,47213,412,552SH SOLE 13,412,55200
SOMALOGIC INCCLASS A COM83444K10517,4601,500,000SH SOLE 1,500,00000
SOMALOGIC INC*W EXP 08/31/20283444K113367110,000SH SOLE 110,00000
SONENDO INCCOM8354311073,851668,505SH SOLE 668,50500
SPRINGWORKS THERAPEUTICS INCCOM85205L107300,5984,849,912SH SOLE 4,849,91200
SUMMIT HEALTHCRE ACQUISTN COUNIT 06/03/2026G8566R1289,9501,000,000SH SOLE 1,000,00000
SURROZEN INCCOM86889P1092,663413,446SH SOLE 413,44600
SURROZEN INC*W EXP 08/01/20386889P117192166,666SH SOLE 166,66600
TARSUS PHARMACEUTICALS INCCOM87650L10329,1691,296,416SH SOLE 1,296,41600
TRAVERE THERAPEUTICS INCNOTE 2.500% 9/1761299AB2484,73645,000,000PRN SOLE 45,000,00000
TRAVERE THERAPEUTICS INCCOM89422G10757,2861,845,555SH SOLE 1,845,55500
TREACE MED CONCEPTS INCCOM89455T10918,271980,186SH SOLE 980,18600
TYRA BIOSCIENCES INCCOM90240B1069,474673,352SH SOLE 673,35200
UNITED THERAPEUTICS CORP DELCOM91307C10220,32594,064SH SOLE 94,06400
VBI VACCINES INC CDACOM NEW91822J103122,46352,335,002SH SOLE 52,335,00200
VERONA PHARMA PLCSPONSORED ADS92505010619,2702,867,510SH SOLE 2,867,51000
VERRICA PHARMACEUTICALS INCCOM92511W10833,0713,610,412SH SOLE 3,610,41200
VERU INCCOM92536C10326,2184,451,342SH SOLE 4,451,34200
VIATRIS INCCOM92556V10613,5901,004,419SH SOLE 1,004,41900
VIRIDIAN THERAPEUTICS INCCOM92790C10428,1341,423,053SH SOLE 1,423,05300
VYNE THERAPEUTICS INCCOM92941V2092,2222,178,022SH SOLE 2,178,02200
XENON PHARMACEUTICALS INCCOM98420N10575,3342,411,447SH SOLE 2,411,44700
ZENTALIS PHARMACEUTICALS INCCOM98943L10736,192430,544SH SOLE 430,54400
ZYMEWORKS INCCOM98985W10260,3123,679,845SH SOLE 3,679,84500