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Perceptive Advisors

Filed: 16 May 22, 4:31pm

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number:3235-0006
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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ABSCI CORPORATIONCOM00091E10910,0401,190,952SH SOLE 1,190,95200
ACADIA PHARMACEUTICALS INCCOM0042251086,899284,853SH SOLE 284,85300
ACCOLADE INCCOM00437E1025,807330,682SH SOLE 330,68200
ACLARIS THERAPEUTICS INCCOM00461U1056,607383,239SH SOLE 383,23900
ACUMEN PHARMACEUTICALS INCCOM00509G2092,334596,942SH SOLE 596,94200
ADMA BIOLOGICS INCCOM00089910421,83811,933,387SH SOLE 11,933,38700
AGILE THERAPEUTICS INCCOM00847L100178,44721,294,485SH SOLE 21,294,48500
ALBIREO PHARMA INCCOM01345P10670,4032,360,139SH SOLE 2,360,13900
ALDEYRA THERAPEUTICS INCCOM01438T10644,0239,903,879SH SOLE 9,903,87900
ALNYLAM PHARMACEUTICALS INCCOM02043Q10729,405180,079SH SOLE 180,07900
AMICUS THERAPEUTICS INCCOM03152W109260,95427,555,845SH SOLE 27,555,84500
AMYLYX PHARMACEUTICALS INCCOM03237H10118,9421,474,107SH SOLE 1,474,10700
APELLIS PHARMACEUTICALS INCCOM03753U10675,2851,481,700SH SOLE 1,481,70000
ARCUS BIOSCIENCES INCCOM03969F10912,782405,000SH SOLE 405,00000
ARTIVION INCCOM22890310013,164615,703SH SOLE 615,70300
ASTRIA THERAPEUTICS INCCOM04635X1028,5961,281,197SH SOLE 1,281,19700
ATHENEX INCCOM04685N10311,22513,532,467SH SOLE 13,532,46700
ATHIRA PHARMA INCCOM04746L10446,2503,425,916SH SOLE 3,425,91600
AXONICS INCCOM05465P10121,360341,211SH SOLE 341,21100
BCLS ACQUISITION CORPCOM CL AG0904B1059,8701,000,000SH SOLE 1,000,00000
BELLUS HEALTH INC NEWCOM NEW07987C20455,9808,136,630SH SOLE 8,136,63000
BRIDGEBIO PHARMA INCCOM10806X10238,9693,839,380SH SOLE 3,839,38000
BUTTERFLY NETWORK INC*W EXP 02/12/202124155110238233,333SH SOLE 233,33300
C4 THERAPEUTICS INCCOM STK12529R10750,5262,082,723SH SOLE 2,082,72300
CAREMAX INCCOM CL A14171W10323,8043,186,663SH SOLE 3,186,66300
CAREMAX INC*W EXP 06/08/20214171W11111460,000SH SOLE 60,00000
CEREVEL THERAPEUTICS HLDNG ICOM15678U128178,0865,086,727SH SOLE 5,086,72700
CHEMOCENTRYX INCCOM16383L10641,4931,655,079SH SOLE 1,655,07900
CINCOR PHARMA INCCOM17240Y10940,6772,319,117SH SOLE 2,319,11700
CLOVER HEALTH INVESTMENTS COCOM CL A18914F1035,3251,500,000SH SOLE 1,500,00000
COGENT BIOSCIENCES INCCOM19240Q20123,8843,188,750SH SOLE 3,188,75000
COHERUS BIOSCIENCES INCCOM19249H10360,6234,695,848SH SOLE 4,695,84800
COHERUS BIOSCIENCES INCNOTE 1.500% 4/119249HAB944,6044,500,000PRN SOLE 4,500,00000
COLLEGIUM PHARMACEUTICAL INCNOTE 2.625% 2/119459JAA289,4749,500,000PRN SOLE 9,500,00000
CONCERT PHARMACEUTICALS INCCOM2060221057,2472,150,641SH SOLE 2,150,64100
CRINETICS PHARMACEUTICALS INCOM22663K107113,3395,163,517SH SOLE 5,163,51700
CUE HEALTH INCCOM22979010010,1951,580,607SH SOLE 1,580,60700
DA32 LIFE SCNCE TEC ACQSTN CCLASS A COM23312M1064,858500,000SH SOLE 500,00000
DARIOHEALTH CORPCOM NEW23725P2091,915327,869SH SOLE 327,86900
DAY ONE BIOPHARMACEUTICALS ICOM23954D1095,516556,047SH SOLE 556,04700
DICE THERAPEUTICS INCCOM23345J10428,9891,515,361SH SOLE 1,515,36100
ENVVENO MEDICAL CORPORATIONCOM29415J1064,978781,615SH SOLE 781,61500
EQRX INC*W EXP 12/17/20226886C115218250,000SH SOLE 250,00000
ESTABLISHMENT LABS HLDGS INCCOMG3124910830,351450,374SH SOLE 450,37400
EVOLENT HEALTH INCCL A30050B1018,075250,000SH SOLE 250,00000
FERRARI N VCOMN3167Y1031,3526,200SH SOLE 6,20000
FULCRUM THERAPEUTICS INCCOM3596161096,956294,118SH SOLE 294,11800
FUSION PHARMACEUTICALS INCCOM36118A1009,5341,227,017SH SOLE 1,227,01700
GLOBAL BLOOD THERAPEUTICS INCOM37890U108134,8363,892,493SH SOLE 3,892,49300
GRAPHITE BIO INCCOM38870X1041,662325,854SH SOLE 325,85400
HEALTH CATALYST INCCOM42225T10712,899493,662SH SOLE 493,66200
HEALTH SCIENCES ACQ CORP 2ORD SHSG4411D1094,460450,000SH SOLE 450,00000
HORIZON THERAPEUTICS PLCSHSG46188101142,8641,357,903SH SOLE 1,357,90300
HYPERFINE INCCOM CL A44916K1065,3101,500,000SH SOLE 1,500,00000
ICOSAVAX INCCOM45114M1099,7091,379,137SH SOLE 1,379,13700
IMMATICS N.VSHSN4444510919,9752,500,000SH SOLE 2,500,00000
IMMUNEERING CORPCLASS A COM45254E1074,406681,051SH SOLE 681,05100
INARI MED INCCOM45332Y1092,71930,000SH SOLE 30,00000
INHIBRX INCCOM45720L10739,6861,781,235SH SOLE 1,781,23500
INVITAE CORPCOM46185L1034,420554,585SH SOLE 554,58500
IOVANCE BIOTHERAPEUTICS INCCOM462260100203,15012,201,261SH SOLE 12,201,26100
ISOPLEXIS CORPCOM46500510614,0474,095,498SH SOLE 4,095,49800
IVERIC BIO INCCOM46583P10287,9445,225,415SH SOLE 5,225,41500
KRONOS BIO INCCOM50107A10417,5042,421,142SH SOLE 2,421,14200
LANDOS BIOPHARMA INCCOM51506910221,93314,869,915SH SOLE 14,869,91500
LEAP THERAPEUTICS INCCOM52187K10113,9157,951,448SH SOLE 7,951,44800
LEGEND BIOTECH CORPSPONSORED ADS52490G10222,391616,141SH SOLE 616,14100
LIANBIOSPONSORED ADS53000N108208,94756,319,960SH SOLE 56,319,96000
LYRA THERAPEUTICS INCCOM55234L10512,9553,222,560SH SOLE 3,222,56000
MACROGENICS INCCOM55609910913,7421,559,789SH SOLE 1,559,78900
MADRIGAL PHARMACEUTICALS INCCOM55886810527,305278,286SH SOLE 278,28600
MEIRAGTX HLDGS PLCCOMG5966510296,2016,948,277SH SOLE 6,948,27700
MERUS N VCOMN5749R1005,527209,046SH SOLE 209,04600
MINERVA SURGICAL INCCOM60343F10622650,268SH SOLE 50,26800
MIRATI THERAPEUTICS INCCOM60468T105195,7422,380,710SH SOLE 2,380,71000
MORPHIC HLDG INCCOM61775R10530,808767,327SH SOLE 767,32700
MOTUS GI HLDGS INCCOM62014P1086481,800,542SH SOLE 1,800,54200
NANOBIOTIX SASPONSORED ADS63009J1077,8851,059,800SH SOLE 1,059,80000
NANOSTRING TECHNOLOGIES INCNOTE 2.625% 3/063009RAD111,0361,000,000PRN SOLE 1,000,00000
NAUTILUS BIOTECHNOLOGY INCCOM63909J10839,5429,111,151SH SOLE 9,111,15100
NEPTUNE WELLNESS SOLUTIONS ICOM64079L1054452,000,000SH SOLE 2,000,00000
NEUROCRINE BIOSCIENCES INCCOM64125C10937,091395,639SH SOLE 395,63900
NEVRO CORPCOM64157F10334,504477,037SH SOLE 477,03700
NUVALENT INCCOM67070310724,3301,751,601SH SOLE 1,751,60100
NUVATION BIO INCCOM CL A67080N1019,3081,769,701SH SOLE 1,769,70100
ONCORUS INCCOM68236R1031,339752,241SH SOLE 752,24100
OUTSET MED INCCOM69014510785,5061,883,399SH SOLE 1,883,39900
PEAR THERAPEUTICS INCCLASS A COM7047231054,677926,232SH SOLE 926,23200
PENUMBRA INCCOM70975L10731,896143,591SH SOLE 143,59100
POINT BIOPHARMA GLOBAL INCCOM7305411099,5161,193,995SH SOLE 1,193,99500
PRIVIA HEALTH GROUP INCCOM74276R1025,705213,423SH SOLE 213,42300
PROCEPT BIOROBOTICS CORPCOM74276L10552,0751,488,284SH SOLE 1,488,28400
PROMETHEUS BIOSCIENCES INCCOM74349U10892,1562,440,582SH SOLE 2,440,58200
PROTARA THERAPEUTICS INCCOM STK74365U1071,960383,526SH SOLE 383,52600
PROTHENA CORP PLCSHSG728001082,38265,144SH SOLE 65,14400
PROVENTION BIO INCCOM74374N1025,794791,549SH SOLE 791,54900
PULMONX CORPCOM74584810113,342537,779SH SOLE 537,77900
PYXIS ONCOLOGY INCCOMMON STOCK7473241016,1761,528,812SH SOLE 1,528,81200
QUOTIENT LTDSHSG7326810719,44116,200,818SH SOLE 16,200,81800
RAIN THERAPEUTICS INCCOM75082Q10512,5922,483,619SH SOLE 2,483,61900
RAPID MICRO BIOSYSTEMS INCCLASS A COM75340L1041,295190,745SH SOLE 190,74500
RAPT THERAPEUTICS INCCOM75382E10961,5712,799,962SH SOLE 2,799,96200
REATA PHARMACEUTICALS INCCL A75615P1031,45744,475SH SOLE 44,47500
RELAY THERAPEUTICS INCCOM75943R10258,1561,943,097SH SOLE 1,943,09700
RELMADA THERAPEUTICS INCCOM75955J4024,085151,350SH SOLE 151,35000
RESEARCH ALLIANCE CORP IICOM CL A7608731099,7601,000,000SH SOLE 1,000,00000
REVANCE THERAPEUTICS INCCOM7613301092,682137,514SH SOLE 137,51400
ROCKET PHARMACEUTICALS INCCOM77313F10626,6151,678,090SH SOLE 1,678,09000
ROCKLEY PHOTONICS HOLDINGS L*W EXP 08/11/202G7614L117425500,000SH SOLE 500,00000
SCIENCE 37 HOLDINGS INCCOM8086441088,0251,500,000SH SOLE 1,500,00000
SEMA4 HOLDINGS CORPCOM CL A81663L1017,6752,500,000SH SOLE 2,500,00000
SIGHT SCIENCES INCCOM82657M1054,508390,000SH SOLE 390,00000
SINGULAR GENOMICS SYSTEMS INCOM82933R10023,0643,655,207SH SOLE 3,655,20700
SOLID BIOSCIENCES INCCOM83422E10516,09513,412,552SH SOLE 13,412,55200
SOMALOGIC INCCLASS A COM83444K10512,0301,500,000SH SOLE 1,500,00000
SOMALOGIC INC*W EXP 08/31/20283444K113235110,000SH SOLE 110,00000
SONENDO INCCOM8354311072,681668,505SH SOLE 668,50500
SPRINGWORKS THERAPEUTICS INCCOM85205L107255,5604,527,993SH SOLE 4,527,99300
SUMMIT HEALTHCRE ACQUISTN COUNIT 06/03/2026G8566R1289,7771,000,000SH SOLE 1,000,00000
SURROZEN INCCOM86889P10923477,723SH SOLE 77,72300
SURROZEN INC*W EXP 08/01/20386889P11742166,666SH SOLE 166,66600
TARSUS PHARMACEUTICALS INCCOM87650L10321,8051,296,416SH SOLE 1,296,41600
TRAVERE THERAPEUTICS INCCOM89422G10747,5601,845,555SH SOLE 1,845,55500
TRAVERE THERAPEUTICS INCNOTE 2.250% 3/089422GAA5474,08945,000,000PRN SOLE 45,000,00000
TREACE MED CONCEPTS INCCOM89455T10918,365971,192SH SOLE 971,19200
TYRA BIOSCIENCES INCCOM90240B1065,290494,403SH SOLE 494,40300
VBI VACCINES INC CDACOM NEW91822J10386,87652,335,002SH SOLE 52,335,00200
VERONA PHARMA PLCSPONSORED ADS92505010615,1913,044,303SH SOLE 3,044,30300
VERRICA PHARMACEUTICALS INCCOM92511W10829,2803,610,412SH SOLE 3,610,41200
VERU INCCOM92536C10321,0684,361,998SH SOLE 4,361,99800
VIRIDIAN THERAPEUTICS INCCOM92790C10426,3121,423,053SH SOLE 1,423,05300
XENON PHARMACEUTICALS INCCOM98420N10573,7182,411,447SH SOLE 2,411,44700
ZENTALIS PHARMACEUTICALS INCCOM98943L10723,140501,509SH SOLE 501,50900
ZYMERGEN INCCOM98985X1002,553883,332SH SOLE 883,33200
ZYMEWORKS INCCOM98985W10234,8835,325,615SH SOLE 5,325,61500