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Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We consent to the incorporation by reference in Registration Statement Nos.333-233654 and333-223850 on FormS-3 and Nos.330-230162,333-210259 and333-205773 on FormS-8 of our report dated March 16, 2020, relating to the consolidated financial statements of Chiasma, Inc. appearing in this Annual Report on Form10-K for the year ended December 31, 2019.
/s/ Deloitte & Touche LLP
Boston, MA
March 16, 2020