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Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the incorporation by reference in the Registration Statements on Form S-8 (No. 333-230213, No. 333-213120, No. 333-216532, No. 333-223500 and No. 333-225294) and Form S-3 (No. 333-220314, No. 333-227216 and No. 333-234414) of Protagonist Therapeutics, Inc. of our report dated March 10, 2020 relating to the financial statements, which appears in Protagonist Therapeutics, Inc.’s Annual Report on Form 10-K for the year ended December 31, 2019.
/s/ PricewaterhouseCoopers LLP
San Jose, CA
March 10, 2020