AMPE Ampio Pharmaceuticals

Filed: 5 May 21, 4:10pm

Exhibit 32.1


Certification Pursuant to 18 U.S.C. Section 1350, as Adopted

Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

In connection with the filing of the quarterly report on Form 10-Q for the quarter ended March 31, 2021 (the “Report”) by Ampio Pharmaceuticals, Inc. (the “Company”), each of the undersigned hereby certifies to his knowledge that:

1.The Report fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended, and

2.The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Ay 10

Dated: May 5, 2021

/s/ Michael Macaluso


Michael Macaluso


Chairman and Chief Executive Officer



Dated: May 5, 2021

/s/ Daniel G. Stokely


Daniel G. Stokely


Chief Financial Officer and Secretary