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Sio Capital Management

Filed: 15 Nov 21, 3:00pm

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number:3235-0006
Expires:Oct 31, 2018
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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
AEGLEA BIO THERAPEUTICS INCCOM00773J1033,546446,000SH SOLE 446,00000
ALBIREO PHARMA INCCOM01345P1066,661213,493SH SOLE 213,49300
ARDELYX INCCOM039697107755572,082SH SOLE 572,08200
ARENA PHARMACEUTICALS INCCOM NEW0400476071,29421,738SH SOLE 21,73800
ASLAN PHARMACEUTICALS LTDADS04522R1012,2621,270,758SH SOLE 1,270,75800
AVEANNA HEALTHCARE HOLDINGS INCCOM05356F10511,2061,397,272SH SOLE 1,397,27200
AYALA PHARMACEUTICALS INCCOM05465V1083,613318,599SH SOLE 318,59900
CARDINAL HEALTH INCCOM14149Y1086,995141,423SH SOLE 141,42300
CYMABAY THERAPEUTICS INCCOM23257D1032,053562,339SH SOLE 562,33900
CATALYST BIOSCIENCES INCCOM NEW14888D2082,564623,892SH SOLE 623,89200
CROSS COUNTRY HEALTHCARE INCCOM2274831044,237199,460SH SOLE 199,46000
CIGNA CORPCOM12552310027,667138,224SH SOLE 138,22400
CAREMAX INCCOM CL A14171W10329730,741SH SOLE 30,74100
CAREMAX INCW EXP 06/08/202614171W1113612,808SH SOLE 12,80800
CENTENE CORPCOM15135B10111,168179,232SH SOLE 179,23200
CURIS INCCOM NEW23126920022,8182,914,127SH SOLE 2,914,12700
CORTEXYME INCCOM22053A1072,03522,200SHPutSOLE 22,20000
CYCLACEL PHARMACEUTICALS INCCOM23254L6032,227422,598SH SOLE 422,59800
PRECISION BIOSCIENCES INCCOM74019P1082,968257,167SH SOLE 257,16700
EUCRATES BIOMEDICAL ACQUISITION CORP.UNIT 10/23/2027G3141W1142,474248,674SH SOLE 248,67400
EVELO BIOSCIENCES INCCOM2997341031,452206,300SHPutSOLE 206,30000
FUSION PHARMACEUTICALS INCCOM36118A1002,057259,763SH SOLE 259,76300
GILEAD SCIENCES INCCOM3755581034,57565,500SH SOLE 65,50000
SPDR GOLD SHARESGOLD SHS78463V10716,841102,553SH SOLE 102,55300
GALAPAGOS NVSPON ADR36315X10111,822224,719SH SOLE 224,71900
HCA HEALTHCARE INCCOM40412C10113,69256,409SH SOLE 56,40900
HERBALIFE NUTRITION LTDCOM SHSG4412G1019,155216,012SH SOLE 216,01200
HEALTHEQUITY INCCOM42226A1074,75773,458SH SOLE 73,45800
HEALTH SCIENCES ACQUISITIONS CORP 2ORD SHSG4411D1092,473250,000SH SOLE 250,00000
HUMACYTE INC*W EXP 09/21/20244486Q11114549,998SH SOLE 49,99800
HORIZON THERAPEUTICS PLCSHSG461881013,21229,319SH SOLE 29,31900
INTEGER HOLDINGS CORPCOM45826H1094,90454,891SH SOLE 54,89100
KURA ONCOLOGY INCCOM50127T1094,276228,318SH SOLE 228,31800
LOGICBIO THERAPEUTICS INCCOM54142F102836182,630SH SOLE 182,63000
LEAP THERAPEUTICS INCCOM52187K1011,764440,000SH SOLE 440,00000
MOLECULIN BIOTECH INCCOM60855D2003,1221,040,529SH SOLE 1,040,52900
MCKESSON CORPCOM58155Q1038,73243,797SH SOLE 43,79700
MEI PHARMA INCCOM NEW55279B2021,176426,047SH SOLE 426,04700
MIRUM PHARMACEUTICALS INCCOM6047491014,960248,978SH SOLE 248,97800
MERCK & CO INCCOM58933Y1059,389125,000SH SOLE 125,00000
NEUBASE THERAPEUTICS INCCOM64132K1023,272906,445SH SOLE 906,44500
NEOLEUKIN THERAPEUTICS INCCOM64049K10427738,312SH SOLE 38,31200
NATUS MEDICAL INCCOM63905010398739,354SH SOLE 39,35400
NYXOAH SASHSB6S7WD10647716,310SH SOLE 16,31000
PROTAGONIST THERAPEUTICS INCCOM74366E1021,59590,000SH SOLE 90,00000
RENOVACOR INCCOM75989E1066,664736,323SH SOLE 736,32300
RENOVACOR INC*W EXP 99/99/99975989E114274400,000SH SOLE 400,00000
RADIUS HEALTH INCCOM NEW7504692073,002241,905SH SOLE 241,90500
RIGEL PHARMACEUTICALS INCCOM NEW7665596033,316913,621SH SOLE 913,62100
RUBIUS THERAPEUTICS INCCOM78116T1031116,200SH SOLE 6,20000
SALARIUS PHARMACEUTICALS INCCOM NEW79400X1071,3811,354,291SH SOLE 1,354,29100
SOLITON INCCOM83425110016,793824,803SH SOLE 824,80300
SPRUCE BIOSCIENCES INCCOM85209E1093,624603,027SH SOLE 603,02700
SIERRA ONCOLOGY INCCOM NEW82640U4042,09295,450SH SOLE 95,45000
SYROS PHARMACEUTICALS INCCOM87184Q1074,026900,677SH SOLE 900,67700
UNIVERSAL HEALTH SERVICES INCCL B91390310013,982101,051SH SOLE 101,05100
UNITED THERAPEUTICS CORPCOM91307C10210,91759,146SH SOLE 59,14600
VINCERX PHARMA INCCOM NEW92731L1061,650102,049SH SOLE 102,04900
VIKING THERAPEUTICS INCCOM92686J1064,150660,813SH SOLE 660,81300
VERTEX PHARMACEUTICALS INCCOM92532F1004,62525,500SH SOLE 25,50000
X4 PHARMACEUTICALS INCCOM98420X1034,256804,597SH SOLE 804,59700