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RTW Investments

Filed: 13 Aug 21, 4:31pm

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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OMB Number:3235-0006
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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
10X GENOMICS INCCL A COM88025U109143,826734,481SH SOLE1,2,3734,48100
5 01 ACQUISITION CORPCOM CL A33836P1053,908392,000SH SOLE1,2,3392,00000
908 DEVICES INCCOM65443P1021,55040,000SH SOLE1,2,340,00000
ACUTUS MED INCCOM0051111097,672451,834SH SOLE1,2,3451,83400
ADVERUM BIOTECHNOLOGIES INCCOM00773U10825,7537,357,917SH SOLE1,2,37,357,91700
AGENUS INCCOM NEW00847G70562,79011,437,238SH SOLE1,2,311,437,23800
AKOYA BIOSCIENCES INCCOM00974H1041,934100,000SH SOLE1,2,3100,00000
ALNYLAM PHARMACEUTICALS INCCOM02043Q107285,3641,683,362SH SOLE1,2,31,683,36200
APTEVO THERAPEUTICS INCCOM NEW03835L2076,312281,402SH SOLE1,2,3281,40200
APYX MEDICAL CORPORATIONCOM03837C10634,9643,391,279SH SOLE1,2,33,391,27900
ARBUTUS BIOPHARMA CORPCOM03879J10018,1145,978,355SH SOLE1,2,35,978,35500
ARGENX SESPONSORED ADR04016X1019,56031,752SH SOLE1,231,75200
ARYA SCIENCES ACQU CORP IVCL AG316591085,360500,000SH SOLE1,2,3500,00000
ASLAN PHARMACEUTICALS LTDADS04522R10110,7253,250,000SH SOLE1,2,33,250,00000
ATHIRA PHARMA INCCOM04746L10419,5231,906,557SH SOLE1,2,31,906,55700
AVADEL PHARMACEUTICALS PLCSPONSORED ADR05337M10438,6435,741,939SH SOLE1,2,35,741,93900
AVIDITY BIOSCIENCES INCCOM05370A10898,7163,995,000SH SOLE1,2,33,995,00000
AVITA MEDICAL INCCOM05380C1025,746280,000SH SOLE1,2,3280,00000
AXONICS INCCOM05465P101123,2601,943,864SH SOLE1,2,31,943,86400
AXSOME THERAPEUTICS INCCOM05464T104109,0491,616,497SH SOLE1,2,31,616,49700
AZIYO BIOLOGICS INCCOM CL A05479K1061,201125,000SH SOLE1,2,3125,00000
BCLS ACQUISITION CORPCOM CL AG0904B1056,450612,500SH SOLE1,2,3612,50000
BCTG ACQUISITION CORPCOM05492W1036,828600,000SH SOLE1,2,3600,00000
BELLUS HEALTH INC NEWCOM NEW07987C20415,4414,968,017SH SOLE1,2,34,968,01700
BERKELEY LTS INCCOM08431010111,541257,546SH SOLE1,2,3257,54600
BIODESIX INCCOM09075X1081,651125,000SH SOLE1,2,3125,00000
BIOMEA FUSION INCCOM09077A10612,270830,794SH SOLE1,2,3830,79400
BOLT BIOTHERAPEUTICS INCCOM0977021041,954126,365SH SOLE1,2,3126,36500
BRAINSWAY LTDSPONSORED ADS10501L10616,3421,602,181SH SOLE1,2,31,602,18100
BURNING ROCK BIOTECH LTDSPONSORED ADS12233L10788430,000SH SOLE1,2,330,00000
C4 THERAPEUTICS INCCOM STK12529R10781,3272,149,228SH SOLE1,2,32,149,22800
CASTLE BIOSCIENCES INCCOM14843C10558,591799,009SH SOLE1,2,3799,00900
CELLDEX THERAPEUTICS INC NEWCOM NEW15117B202130,7153,908,947SH SOLE1,2,33,908,94700
CEREVEL THERAPEUTICS HLDNG ICOM15678U12812,810500,000SH SOLE1,2,3500,00000
CEREVEL THERAPEUTICS HLDNG I*W EXP 06/09/20215678U1022,398166,666SH SOLE1,2,3166,66600
CHARDAN HEALTHCR ACQSTN 2 COCOM15957T1078,299837,540SH SOLE1,2,3837,54000
CHARDAN HEALTHCR ACQSTN 2 COUNIT 99/99/999915957T2063,644350,000SH SOLE1,2,3350,00000
CLEARSIDE BIOMEDICAL INCCOM18506310420,4874,206,765SH SOLE1,2,34,206,76500
CODEX DNA INCCOM1920031014,400200,000SH SOLE1,2,3200,00000
CONNECT BIOPHARMA HLDGS LTDADS2075231018,789450,000SH SOLE1,2,3450,00000
CUTERA INCCOM23210910835,342720,817SH SOLE1,2,3720,81700
CVRX INCCOM1266381054,200150,000SH SOLE1,2,3150,00000
CYTOKINETICS INCCOM NEW23282W60539,5802,000,000SH SOLE1,2,32,000,00000
CYTOMX THERAPEUTICS INCCOM23284F1058,8681,400,939SH SOLE1,2,31,400,93900
DERMTECH INCCOM24984K105129,6433,118,665SH SOLE1,2,33,118,66500
DICERNA PHARMACEUTICALS INCCOM253031108280,7167,521,859SH SOLE1,2,37,521,85900
ESSA PHARMA INCCOM NEW29668H70887,2503,053,919SH SOLE1,2,33,053,91900
ESTABLISHMENT LABS HLDGS INCCOMG31249108202,5542,319,138SH SOLE1,2,32,319,13800
EXAGEN INCCOM30068X10312,313821,414SH SOLE1,2,3821,41400
FULCRUM THERAPEUTICS INCCOM35961610933,5913,205,291SH SOLE1,2,33,205,29100
GENETRON HLDGS LTDADS37186H10036,6181,818,162SH SOLE1,2,31,818,16200
GH RESEARCH PLCORDINARY SHARESG3855L10642,6612,168,957SH SOLE1,2,32,168,95700
GLOBUS MED INCCL A379577208129,5381,670,811SH SOLE1,2,31,670,81100
GUARDANT HEALTH INCCOM40131M109114,038918,253SH SOLE1,2,3918,25300
HELIX ACQUISITION CORPCOM CL AG4444C1027,763750,000SH SOLE1,2,3750,00000
IDEAYA BIOSCIENCES INCCOM45166A10268,5593,266,255SH SOLE1,2,33,266,25500
ILLUMINA INCCOM452327109228,462482,791SH SOLE1,2,3482,79100
IMMATICS N.VSHSN444451094,064350,000SH SOLE1,2,3350,00000
IMMUNIC INCCOM4525EP10111,289920,814SH SOLE1,2,3920,81400
IMMUNOCORE HLDGS PLCADS45258D10547,8881,245,532SH SOLE1,2,31,245,53200
INMODE LTDSHSM5425M10311,835124,999SH SOLE1,2124,99900
ITAMAR MED LTDSPONSORED ADS4654371016,326268,609SH SOLE1,2,3268,60900
ITEOS THERAPEUTICS INCCOM46565G10444,0301,716,585SH SOLE1,2,31,716,58500
IVERIC BIO INCCOM46583P10242,4206,722,624SH SOLE1,2,36,722,62400
JOHNSON & JOHNSONCOM47816010428,095170,542SH SOLE1,2,3170,54200
LA JOLLA PHARMACEUTICAL COCOM PAR $.0001 25034596049,9632,327,903SH SOLE1,2,32,327,90300
LANDOS BIOPHARMA INCCOM51506910248,4574,275,722SH SOLE1,2,34,275,72200
LIFESCI ACQUISITION II CORPCOM53229E1039,750975,000SH SOLE1,2,3975,00000
MACROGENICS INCCOM55609910968,4102,546,925SH SOLE1,2,32,546,92500
MARAVAI LIFESCIENCES HLDGS ICOM CL A56600D1072,92170,000SH SOLE1,2,370,00000
MASIMO CORPCOM574795100200,315826,210SH SOLE1,2,3826,21000
MEDICUS SCIENCES ACQUISITION*W EXP 02/12/202G5960S1243433,331SH SOLE1,2,333,33100
MEDICUS SCIENCES ACQUISITIONCL A SHSG5960S1082,895300,000SH SOLE1,2,3300,00000
MILESTONE PHARMACEUTICALS INCOM59935V10723,7334,315,102SH SOLE1,2,34,315,10200
MIMEDX GROUP INCCOM60249610133,7812,700,320SH SOLE1,2,32,700,32000
MIRATI THERAPEUTICS INCCOM60468T105235,4351,457,532SH SOLE1,2,31,457,53200
MIROMATRIX MED INCCOM60471P1083,262280,000SH SOLE1,2,3280,00000
MONTE ROSA THERAPEUTICS INCCOM61225M10225,2281,214,572SH SOLE1,2,31,214,57200
NANOSTRING TECHNOLOGIES INCCOM63009R10952,093804,029SH SOLE1,2,3804,02900
NATERA INCCOM632307104194,3901,712,234SH SOLE1,2,31,712,23400
NAUTILUS BIOTECHNOLOGY INCCOM63909J10810,3831,100,000SH SOLE1,2,31,100,00000
NEOGENOMICS INCCOM NEW64049M20913,139311,111SH SOLE1,2,3311,11100
OLINK HLDG ABSPONSORED ADS68071010042,9631,248,188SH SOLE1,2,31,248,18800
OUTSET MED INCCOM69014510736,843737,152SH SOLE1,2,3737,15200
OYSTER PT PHARMA INCCOM69242L10631,9941,861,209SH SOLE1,2,31,861,20900
PERSONALIS INCCOM71535D1063,226127,501SH SOLE1,2127,50100
PMV PHARMACEUTICALS INCCOM69353Y10316,538484,133SH SOLE1,2,3484,13300
PROFOUND MED CORPCOM NEW74319B5021,998122,098SH SOLE1,2,3122,09800
PROGENITY INCCOM74319F107357100,000SH SOLE1,2,3100,00000
PROMETHEUS BIOSCIENCES INCCOM74349U10875,9893,264,031SH SOLE1,2,33,264,03100
PROQR THRAPEUTICS N VSHS EURON7154210943,4276,443,113SH SOLE1,2,36,443,11300
PROTAGONIST THERAPEUTICS INCCOM74366E102157,4123,507,390SH SOLE1,2,33,507,39000
PTC THERAPEUTICS INCCOM69366J200223,7765,293,966SH SOLE1,2,35,293,96600
PULMONX CORPCOM74584810149,8381,129,600SH SOLE1,2,31,129,60000
QUIDEL CORPCOM74838J101112,558878,533SH SOLE1,2,3878,53300
REGENXBIO INCCOM75901B10768,2881,757,743SH SOLE1,2,31,757,74300
RELMADA THERAPEUTICS INCCOM75955J40249,2321,538,026SH SOLE1,2,31,538,02600
RESEARCH ALLIANCE CORP IICOM CL A7608731096,459637,000SH SOLE1,2,3637,00000
ROCKET PHARMACEUTICALS INCCOM77313F106663,92014,990,286SH SOLE1,2,314,990,28600
SCHOLAR ROCK HLDG CORPCOM80706P1034,671161,612SH SOLE1,2,3161,61200
SINGULAR GENOMICS SYSTEMS INCOM82933R1002,748100,000SH SOLE1,2,3100,00000
SPDR S&P 500 ETF TRTR UNIT78462F103426,457996,255SH SOLE1,2,3996,25500
STOKE THERAPEUTICS INCCOM86150R107122,6653,644,248SH SOLE1,2,33,644,24800
SUMMIT HEALTHCRE ACQUISTN COUNIT 06/03/2026G8566R1285,005500,000SH SOLE1,2,3500,00000
TANDEM DIABETES CARE INCCOM NEW875372203111,7581,147,408SH SOLE1,2,31,147,40800
TARSUS PHARMACEUTICALS INCCOM87650L10358,3542,013,601SH SOLE1,2,32,013,60100
TELA BIO INCCOM87238110822,4321,392,434SH SOLE1,2,31,392,43400
THERAPEUTICS ACQUISITION CORCOM CL A88339T1035,034490,000SH SOLE1,2,3490,00000
TRILLIUM THERAPEUTICS INCCOM NEW89620X50620,2862,091,389SH SOLE1,2,32,091,38900
TWIST BIOSCIENCE CORPCOM90184D1002,46218,473SH SOLE1,2,318,47300
VERICEL CORPCOM92346J108237,1724,517,570SH SOLE1,2,34,517,57000
VINCERX PHARMA INCCOM NEW92731L1069,742749,999SH SOLE1,2,3749,99900
ZYMERGEN INCCOM98985X1002,80170,000SH SOLE1,2,370,00000