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Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We consent to the incorporation by reference in Registration Statements No. 333-238630 and 333-239110 on Form S-1 of our report dated March 29, 2021, relating to the financial statements of Vaxcyte, Inc., appearing in the Annual Report on Form 10-K of Vaxcyte, Inc. for the year ended December 31, 2020.
/s/ Deloitte & Touche
San Francisco, California
March 29, 2021