Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the following Registration Statements:
| (2) | Registration Statement (Form S-8 No. 333-231613) pertaining to the 2017 Employee Stock Purchase Plan of Akcea Therapeutics, Inc., |
| (3) | Registration Statement (Form S-8 No. 333-228969) pertaining to the 2015 Equity Incentive Plan of Akcea Therapeutics, Inc., |
| (4) | Registration Statement (Form S-8 No. 333-225730) pertaining to the 2015 Equity Incentive Plan and 2017 Employee Stock Purchase Plan of Akcea Therapeutics, Inc., and |
| (5) | Registration Statement (Form S-8 No. 333-219290) pertaining to the 2015 Equity Incentive Plan and 2017 Employee Stock Purchase Plan of Akcea Therapeutics, Inc; |
of our report dated March 2, 2020, with respect to the consolidated financial statements of Akcea Therapeutics, Inc., included in this Annual Report (Form 10-K) of Akcea Therapeutics, Inc. for the year ended December 31, 2019.
/s/ Ernst & Young LLP
San Diego, California
March 2, 2020