Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in this Registration Statement on Form S-8 of Aptevo Therapeutics Inc. of our report dated March 24, 2022, relating to the consolidated financial statements of Aptevo Therapeutics Inc. (the “Company”) appearing in the Annual Report on Form 10-K of the Company for the year ended December 31, 2021, filed with the Securities and Exchange Commission.
/s/ Moss Adams LLP
Seattle, Washington
June 7, 2022