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Ikarian Capital

Filed: 12 Aug 22, 4:24pm

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number:3235-0006
Expires:Oct 31, 2018
Estimated average burden
hours per response:23.8

COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
AADI BIOSCIENCE INCCOM00032Q1041,274412,343SH SOLE 412,34300
ADICET BIO INCCOM0070021082,091143,214SH SOLE 143,21400
AILERON THERAPEUTICS INCCOM00887A1057522,892,316SH SOLE 2,892,31600
ALDEYRA THERAPEUTICS INCCOM01438T1061,496375,000SH SOLE 375,00000
ALNYLAM PHARMACEUTICALS INCCOM02043Q10742,486291,300SHCallSOLE 291,30000
ALNYLAM PHARMACEUTICALS INCCOM02043Q1078,93161,237SH SOLE 61,23700
ALNYLAM PHARMACEUTICALS INCCOM02043Q1075,82039,900SHPutSOLE 39,90000
ALTAMIRA THERAPEUTICS LTDSHSG0360L1003675,000SH SOLE 75,00000
ALTIMMUNE INCCOM NEW02155H2003,553303,600SHCallSOLE 303,60000
ALTIMMUNE INCCOM NEW02155H20010,499897,359SH SOLE 897,35900
AMGEN INCCOM03116210024,330100,000SHCallSOLE 100,00000
AMYLYX PHARMACEUTICALS INCCOM03237H1016,757350,800SHCallSOLE 350,80000
AMYLYX PHARMACEUTICALS INCCOM03237H1014,750246,554SH SOLE 246,55400
ANEBULO PHARMACEUTICALS INCCOM034569103942181,199SH SOLE 181,19900
APELLIS PHARMACEUTICALS INCCOM03753U1065,572123,200SHCallSOLE 123,20000
APELLIS PHARMACEUTICALS INCCOM03753U1061,89441,900SH SOLE 41,90000
ARCUS BIOSCIENCES INCCOM03969F1091,26650,000SHPutSOLE 50,00000
ARCUS BIOSCIENCES INCCOM03969F10958823,200SHCallSOLE 23,20000
ARDELYX INCCOM0396971079911,680,552SH SOLE 1,680,55200
ASLAN PHARMACEUTICALS LTDADS04522R101185970,747SH SOLE 970,74700
ASTRIA THERAPEUTICS INCCOM04635X1021,776592,123SH SOLE 592,12300
ATHIRA PHARMA INCCOM04746L1042,393784,200SHCallSOLE 784,20000
ATHIRA PHARMA INCCOM04746L104609199,500SHPutSOLE 199,50000
AUTOLUS THERAPEUTICS PLCSPON ADS05280R100912322,217SH SOLE 322,21700
AXSOME THERAPEUTICS INCCOM05464T10419,151500,000SHPutSOLE 500,00000
AXSOME THERAPEUTICS INCCOM05464T10413,404350,000SHCallSOLE 350,00000
AYALA PHARMACEUTICALS INCCOM05465V108759697,316SH SOLE 697,31600
BAUDAX BIO INCCOM NEW07160F20632,966SH SOLE 2,96600
BELLICUM PHARMACEUTICALS INCCOM NEW079481404617523,348SH SOLE 523,34800
BELLUS HEALTH INC NEWCOM NEW07987C204924100,000SHCallSOLE 100,00000
BELLUS HEALTH INC NEWCOM NEW07987C2049,4091,018,327SH SOLE 1,018,32700
BIOGEN INCCOM09062X10322,880112,200SHCallSOLE 112,20000
BIOGEN INCCOM09062X1032281,122SH SOLE 1,12200
BIOMARIN PHARMACEUTICAL INCCOM09061G1018,843106,700SHCallSOLE 106,70000
BIOMARIN PHARMACEUTICAL INCCOM09061G1014,97260,000SH SOLE 60,00000
BLUEPRINT MEDICINES CORPCOM09627Y1093,23264,000SHCallSOLE 64,00000
BRAINSTORM CELL THERAPEUTICSCOM NEW10501E201698253,432SH SOLE 253,43200
BRIDGEBIO PHARMA INCCOM10806X1021,817200,000SHCallSOLE 200,00000
BRIGHT MINDS BIOSCIENCES INCCOM10919W10886105,958SH SOLE 105,95800
CABALETTA BIO INCCOM12674W1091,000944,431SH SOLE 944,43100
CASI PHARMACEUTICALS INCCOM NEW14757U208378132,014SH SOLE 132,01400
CELLDEX THERAPEUTICS INC NEWCOM NEW15117B20216,628616,700SHPutSOLE 616,70000
CELLDEX THERAPEUTICS INC NEWCOM NEW15117B20214,504537,958SH SOLE 537,95800
CELLDEX THERAPEUTICS INC NEWCOM NEW15117B20213,656506,500SHCallSOLE 506,50000
CHEMOMAB THERAPEUTICS LTDSPONSORED ADS16385C104992268,104SH SOLE 268,10400
CHIMERIX INCCOM16934W106917441,203SH SOLE 441,20300
CHINOOK THERAPEUTICS INCCOM16961L1060332,295SH SOLE 332,29500
CLENE INCCOMMON STOCK18563410217770,000SH SOLE 70,00000
CLOVIS ONCOLOGY INCCOM189464100761422,339SH SOLE 422,33900
COGENT BIOSCIENCES INCCOM19240Q2012,256250,000SH SOLE 250,00000
CONNECT BIOPHARMA HLDGS LTDADS207523101591677,859SH SOLE 677,85900
CONTRAFECT CORPCOM NEW212326300615200,000SHPutSOLE 200,00000
CORBUS PHARMACEUTICALS HLDGSCOM21833P103217862,527SH SOLE 862,52700
CYCLACEL PHARMACEUTICALS INCCOM23254L603113104,741SH SOLE 104,74100
DBV TECHNOLOGIES S ASPONSORED ADR23306J1011,401316,939SH SOLE 316,93900
ELEDON PHARMACEUTICALS INCCOM28617K101884362,537SH SOLE 362,53700
ENVERIC BIOSCIENCES INCCOM NEW29405E10948223,834SH SOLE 223,83400
ESPERION THERAPEUTICS INC NECOM29664W10513,0672,054,602SH SOLE 2,054,60200
EVOLUS INCCOM30052C10752945,516SH SOLE 45,51600
FINCH THERAPEUTICS GROUP INCCOM31773D101938330,523SH SOLE 330,52300
FULCRUM THERAPEUTICS INCCOM359616109893182,200SHCallSOLE 182,20000
GALAPAGOS NVSPON ADR36315X1014,83086,865SH SOLE 86,86500
GEMINI THERAPEUTICS INCCOM36870G105749443,096SH SOLE 443,09600
GOSSAMER BIO INCCOM38341P1028,3731,000,387SH SOLE 1,000,38700
GOSSAMER BIO INCCOM38341P1022,800334,500SHCallSOLE 334,50000
HARMONY BIOSCIENCES HLDGS INCOM4131971044,19686,035SH SOLE 86,03500
HEPION PHARMACEUTICALS INCCOM426897104235410,189SH SOLE 410,18900
HORIZON THERAPEUTICS PUB LSHSG4618810112,771160,116SH SOLE 160,11600
HORIZON THERAPEUTICS PUB LSHSG461881017,976100,000SHCallSOLE 100,00000
IMMATICS N.VSHSN444451091,369157,190SH SOLE 157,19000
IMMUNIC INCCOM4525EP10121461,500SH SOLE 61,50000
IMMUNIC INCCOM4525EP10121361,500SHPutSOLE 61,50000
IMMUNOPRECISE ANTIBODIES LTDCOM NEW45257F20023761,433SH SOLE 61,43300
INHIBRX INCCOM45720L10756149,372SH SOLE 49,37200
INSMED INCCOM PAR $.014576693072,465125,000SH SOLE 125,00000
INTERCEPT PHARMACEUTICALS INCOM45845P1081,449105,000SH SOLE 105,00000
INTERCEPT PHARMACEUTICALS INCOM45845P1084,832350,000SHCallSOLE 350,00000
INVENTIVA SAADS46124U1079315,579SH SOLE 15,57900
ITEOS THERAPEUTICS INCCOM46565G1042,061100,000SHCallSOLE 100,00000
IVERIC BIO INCCOM46583P1022,351244,400SHCallSOLE 244,40000
IVERIC BIO INCCOM46583P10247349,099SH SOLE 49,09900
KARUNA THERAPEUTICS INCCOM48576A10012,652100,000SHPutSOLE 100,00000
KARUNA THERAPEUTICS INCCOM48576A10012,651100,000SH SOLE 100,00000
KEZAR LIFE SCIENCES INCCOM49372L1008,8941,075,300SHCallSOLE 1,075,30000
KEZAR LIFE SCIENCES INCCOM49372L10011,6451,408,116SH SOLE 1,408,11600
KRANESHARES TRCSI CHI INTERNET5007673063,277100,000SH SOLE 100,00000
LANTHEUS HLDGS INCCOM5165441036,602100,000SHCallSOLE 100,00000
LARIMAR THERAPEUTICS INCCOM51712510010051,606SH SOLE 51,60600
LYRA THERAPEUTICS INCCOM55234L1051,963347,338SH SOLE 347,33800
MEREO BIOPHARMA GROUP PLCADS589492107199615,856SH SOLE 615,85600
MERUS N VCOMN5749R1001,21653,703SH SOLE 53,70300
MILESTONE PHARMACEUTICALS INCOM59935V1071,261212,400SHCallSOLE 212,40000
MILESTONE PHARMACEUTICALS INCOM59935V1078,1941,379,422SH SOLE 1,379,42200
MIND MEDICINE MINDMED INCCOM SUB VTG60255C10968105,958SH SOLE 105,95800
MUSTANG BIO INCCOM62818Q104145246,824SH SOLE 246,82400
MYMD PHARMACEUTICALS INCCOM62856X10217681,089SH SOLE 81,08900
NEUROCRINE BIOSCIENCES INCCOM64125C1093,76338,600SH SOLE 38,60000
NEXTCURE INCCOM65343E10833671,435SH SOLE 71,43500
OTONOMY INCCOM68906L1050180SH SOLE 18000
OVID THERAPEUTICS INCCOM6904691015926,831SH SOLE 26,83100
PARDES BIOSCIENCES INCCOM69945Q105687223,934SH SOLE 223,93400
PFIZER INCCOM7170811034,19480,000SH SOLE 80,00000
PRAXIS PRECISION MEDICINES ICOM74006W108263107,200SHCallSOLE 107,20000
PROTARA THERAPEUTICS INCCOM STK74365U107756257,853SH SOLE 257,85300
REATA PHARMACEUTICALS INCCL A75615P10363220,805SH SOLE 20,80500
REATA PHARMACEUTICALS INCCL A75615P1034,923162,000SHCallSOLE 162,00000
REGULUS THERAPEUTICS INCCOM75915K309217105,341SH SOLE 105,34100
RELMADA THERAPEUTICS INCCOM75955J4025,698300,000SHCallSOLE 300,00000
RELMADA THERAPEUTICS INCCOM75955J4025,362282,300SHPutSOLE 282,30000
RENEO PHARMACEUTICALS INCCOM75974E103491185,597SH SOLE 185,59700
RENOVACOR INCCOM75989E106595293,283SH SOLE 293,28300
RIGEL PHARMACEUTICALS INCCOM NEW766559603794702,773SH SOLE 702,77300
SAGE THERAPEUTICS INCCOM78667J1088,075250,000SHCallSOLE 250,00000
SAREPTA THERAPEUTICS INCCOM8036071007,495100,000SHCallSOLE 100,00000
SAREPTA THERAPEUTICS INCCOM8036071001,87425,000SH SOLE 25,00000
SATSUMA PHARMACEUTICALS INCCOM80405P1072,704653,448SH SOLE 653,44800
SCPHARMACEUTICALS INCCOM8106481054,261884,008SH SOLE 884,00800
SERES THERAPEUTICS INCCOM81750R1021,854540,624SH SOLE 540,62400
SPDR SER TRS&P BIOTECH78464A87025,994350,000SHPutSOLE 350,00000
STEALTH BIOTHERAPEUTICS CORPSPONSORED ADS85789A105127501,836SH SOLE 501,83600
SYNAPTOGENIX INCCOM NEW87167T201614121,191SH SOLE 121,19100
SYNLOGIC INCCOM87166L100545474,360SH SOLE 474,36000
TEMPEST THERAPEUTICS INCCOM87978U10813261,827SH SOLE 61,82700
TERNS PHARMACEUTICALS INCCOM8808811071,736700,000SH SOLE 700,00000
TRACON PHARMACEUTICALS INCCOM NEW89237H2095,5772,788,853SH SOLE 2,788,85300
TRICIDA INCCOM89610F10189992,900SHPutSOLE 92,90000
UNITED THERAPEUTICS CORP DELCOM91307C1029,42640,000SH SOLE 40,00000
VASCULAR BIOGENICS LTDCOMM968831091,337830,007SH SOLE 830,00700
VAXCYTE INCCOM92243G1084,918225,991SH SOLE 225,99100
VERASTEM INCCOM92337C104265228,023SH SOLE 228,02300
VERONA PHARMA PLCSPONSORED ADS925050106200300,000SH SOLE 300,00000
VERTEX PHARMACEUTICALS INCCOM92532F10011,27140,000SH SOLE 40,00000
VIKING THERAPEUTICS INCCOM92686J1062,414835,275SH SOLE 835,27500
VIRIDIAN THERAPEUTICS INCCOM92790C1043,472300,000SHCallSOLE 300,00000
WAVE LIFE SCIENCES LTDSHSY9530810531898,039SH SOLE 98,03900
X4 PHARMACEUTICALS INCCOM98420X1031,6211,679,748SH SOLE 1,679,74800
XENON PHARMACEUTICALS INCCOM98420N1057,283239,441SH SOLE 239,44100
YUMANITY THERAPEUTICS INCCOM98872L102190104,392SH SOLE 104,39200
ZAI LAB LTDADR98887Q10427881,843SH SOLE 81,84300