Document and Entity Information
Document and Entity Information - shares | 6 Months Ended | |
Jun. 30, 2023 | Jul. 31, 2023 | |
Cover [Abstract] | ||
Document Type | 10-Q | |
Amendment Flag | false | |
Document Period End Date | Jun. 30, 2023 | |
Document Fiscal Year Focus | 2023 | |
Document Fiscal Period Focus | Q2 | |
Entity Registrant Name | CULLINAN ONCOLOGY, INC. | |
Current Fiscal Year End Date | --12-31 | |
Document Quarterly Report | true | |
Document Transition Report | false | |
Entity Central Index Key | 0001789972 | |
Entity File Number | 001-39856 | |
Entity Incorporation, State or Country Code | DE | |
Entity Tax Identification Number | 81-3879991 | |
Entity Address, Address Line One | One Main Street | |
Entity Address, Address Line Two | Suite 1350 | |
Entity Address, City or Town | Cambridge | |
Entity Address, Country | MA | |
Entity Address, Postal Zip Code | 02142 | |
City Area Code | 617 | |
Local Phone Number | 410-4650 | |
Title of 12(b) Security | Common Stock, par value $0.0001 per share | |
Trading Symbol | CGEM | |
Security Exchange Name | NASDAQ | |
Entity Current Reporting Status | Yes | |
Entity Interactive Data Current | Yes | |
Entity Filer Category | Non-accelerated Filer | |
Entity Small Business | true | |
Entity Emerging Growth Company | true | |
Entity Ex Transition Period | false | |
Entity Shell Company | false | |
Entity Common Stock, Shares Outstanding | 42,734,644 |
CONSOLIDATED BALANCE SHEETS
CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands | Jun. 30, 2023 | Dec. 31, 2022 |
Current assets: | ||
Cash and cash equivalents | $ 141,834 | $ 156,152 |
Short-term investments | 349,964 | 311,140 |
Prepaid expenses and other current assets | 6,437 | 7,180 |
Total current assets | 498,235 | 474,472 |
Property and equipment, net | 1,158 | 1,174 |
Operating lease right-of-use assets | 3,501 | 4,130 |
Other assets | 459 | 459 |
Long-term investments | 18,631 | 80,882 |
Total assets | 521,984 | 561,117 |
Current liabilities: | ||
Accounts payable | 2,493 | 2,660 |
Accrued expenses and other current liabilities | 15,531 | 14,135 |
Income tax payable | 0 | 4,282 |
Operating lease liabilities, current | 1,652 | 1,421 |
Total current liabilities | 19,676 | 22,498 |
Long-term liabilities: | ||
Operating lease liabilities, net of current portion | 2,734 | 3,590 |
Total liabilities | 22,410 | 26,088 |
Commitments and contingencies (Note 11) | ||
Stockholders' equity: | ||
Preferred stock, $0.0001 par value, 10,000,000 shares authorized as of June 30, 2023 and December 31, 2022; 647,500 and no shares issued and outstanding as of June 30, 2023 and December 31, 2022, respectively. | 0 | 0 |
Common stock, $0.0001 par value, 150,000,000 shares authorized as of June 30, 2023 and December 31, 2022; 42,735,304 and 45,796,449 shares issued and outstanding as of June 30, 2023 and December 31, 2022, respectively | 4 | 5 |
Additional paid-in capital | 639,066 | 585,320 |
Accumulated other comprehensive loss | (1,625) | (2,601) |
Accumulated deficit | (137,871) | (47,695) |
Total Cullinan stockholders' equity | 499,574 | 535,029 |
Noncontrolling interests | 0 | 0 |
Total stockholders' equity | 499,574 | 535,029 |
Total liabilities and stockholders' equity | $ 521,984 | $ 561,117 |
CONSOLIDATED BALANCE SHEETS (Pa
CONSOLIDATED BALANCE SHEETS (Parenthetical) - $ / shares | Jun. 30, 2023 | Dec. 31, 2022 |
Statement of Financial Position [Abstract] | ||
Preferred Stock par value | $ 0.0001 | $ 0.0001 |
Preferred Stock, shares authorized | 10,000,000 | 10,000,000 |
Preferred Stock, Share issued | 647,500 | 0 |
Preferred Stock, Shares Outstanding | 647,500 | 0 |
Common stock, par value | $ 0.0001 | $ 0.0001 |
Common stock, shares authorized | 150,000,000 | 150,000,000 |
Common stock, shares issued | 42,735,304 | 45,796,449 |
Common stock, shares outstanding | 42,735,304 | 45,796,449 |
CONSOLIDATED STATEMENTS OF OPER
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME (LOSS) - USD ($) shares in Thousands, $ in Thousands | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2023 | Jun. 30, 2022 | Jun. 30, 2023 | Jun. 30, 2022 | |
Income Statement [Abstract] | ||||
Income (loss) from operations | $ (37,605) | $ 239,679 | $ (100,361) | $ 207,022 |
Operating expenses: | ||||
Research and development | 27,391 | 26,411 | 79,487 | 50,947 |
General and administrative | 10,214 | 10,695 | 20,874 | 18,816 |
Total operating expenses | 37,605 | 37,106 | 100,361 | 69,763 |
Gain on sale of Cullinan Pearl | 0 | 276,785 | 0 | 276,785 |
Other income (expense): | ||||
Interest income | 5,322 | 697 | 9,830 | 894 |
Other income (expense), net | 69 | (241) | 176 | 241 |
Net income (loss) before income taxes | (32,214) | 240,135 | (90,355) | 207,675 |
Income tax expense | 0 | 66,070 | 0 | 46,502 |
Net income (loss) | (32,214) | 174,065 | (90,355) | 161,173 |
Net loss attributable to noncontrolling interests | 0 | (833) | (179) | (1,627) |
Net income (loss) attributable to common stockholders of Cullinan | (32,214) | 174,898 | (90,176) | 162,800 |
Comprehensive income (loss): | ||||
Net income (loss) | (32,214) | 174,065 | (90,355) | 161,173 |
Unrealized gain (loss) on investments | (383) | (499) | 976 | (2,795) |
Comprehensive income (loss) | (32,597) | 173,566 | (89,379) | 158,378 |
Comprehensive loss attributable to noncontrolling interests | 0 | (833) | (179) | (1,627) |
Comprehensive income (loss) attributable to Cullinan | $ (32,597) | $ 174,399 | $ (89,200) | $ 160,005 |
Net income (loss) per share: | ||||
Basic | $ (0.82) | $ 3.90 | $ (2.24) | $ 3.65 |
Diluted | $ (0.82) | $ 3.77 | $ (2.24) | $ 3.51 |
Weighted-average shares used in computing net income (loss) per share: | ||||
Weighted-average common stock outstanding - basic | 39,952 | 44,873 | 40,315 | 44,654 |
Diluted | 39,952 | 46,381 | 40,315 | 46,389 |
CONSOLIDATED STATEMENTS OF STOC
CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands | Total | Preferred Stock | Common Stock | Additional Paid-In Capital | Accumulated Other Comprehensive Loss | Accumulated Deficit | Noncontrolling Interest in Subsidiaries |
Balances at Dec. 31, 2021 | $ 425,374 | $ 4 | $ 584,714 | $ (838) | $ (158,909) | $ 403 | |
Balances, shares at Dec. 31, 2021 | 44,292,102 | ||||||
Net issuance of common stock under equity-based compensation plans | (1,566) | (1,566) | |||||
Contributions from noncontrolling interests | 1,153 | 1,153 | |||||
Net issuance of common stock under equity-based compensation plans, shares | 367,924 | ||||||
Equity-based compensation | 6,565 | 6,559 | 6 | ||||
Unrealized gain (loss) on investments | (2,296) | (2,296) | |||||
Net income (loss) | (12,892) | (12,098) | (794) | ||||
Balances at Mar. 31, 2022 | 419,470 | $ 4 | 592,839 | (3,134) | (171,007) | 768 | |
Balances, shares at Mar. 31, 2022 | 44,660,026 | ||||||
Balances at Dec. 31, 2021 | 425,374 | $ 4 | 584,714 | (838) | (158,909) | 403 | |
Balances, shares at Dec. 31, 2021 | 44,292,102 | ||||||
Unrealized gain (loss) on investments | (2,795) | ||||||
Net income (loss) | 161,173 | ||||||
Balances at Jun. 30, 2022 | 604,618 | $ 5 | 604,275 | (3,633) | 3,891 | 80 | |
Balances, shares at Jun. 30, 2022 | 45,396,398 | ||||||
Balances at Mar. 31, 2022 | 419,470 | $ 4 | 592,839 | (3,134) | (171,007) | 768 | |
Balances, shares at Mar. 31, 2022 | 44,660,026 | ||||||
Net issuance of common stock under equity-based compensation plans | (2,835) | $ (1) | (2,834) | ||||
Contributions from noncontrolling interests | 139 | 139 | |||||
Net issuance of common stock under equity-based compensation plans, shares | 736,372 | ||||||
Equity-based compensation | 8,608 | 8,602 | 6 | ||||
Unrealized gain (loss) on investments | (499) | (499) | |||||
Net income (loss) | 174,065 | 174,898 | (833) | ||||
Balances at Jun. 30, 2022 | 604,618 | $ 5 | 604,275 | (3,633) | 3,891 | 80 | |
Balances, shares at Jun. 30, 2022 | 45,396,398 | ||||||
Balances at Dec. 31, 2022 | 535,029 | $ 5 | 585,320 | (2,601) | (47,695) | 0 | |
Balances, shares at Dec. 31, 2022 | 45,796,449 | ||||||
Issuance of preferred stock in exchange for common stock, Share | 647,500 | (6,475,000) | |||||
Issuance of preferred stock in exchange for common stock | $ (1) | 1 | |||||
Net issuance of common stock under equity-based compensation plans | (36) | (36) | |||||
Contributions from noncontrolling interests | 179 | 179 | |||||
Net issuance of common stock under equity-based compensation plans, shares | 22,152 | ||||||
Equity-based compensation | 7,259 | 7,259 | |||||
Unrealized gain (loss) on investments | 1,359 | 1,359 | |||||
Net income (loss) | (58,141) | (57,962) | (179) | ||||
Balances at Mar. 31, 2023 | 485,649 | $ 4 | 592,544 | (1,242) | (105,657) | 0 | |
Balances, shares at Mar. 31, 2023 | 647,500 | 39,343,601 | |||||
Balances at Dec. 31, 2022 | 535,029 | $ 5 | 585,320 | (2,601) | (47,695) | 0 | |
Balances, shares at Dec. 31, 2022 | 45,796,449 | ||||||
Unrealized gain (loss) on investments | 976 | ||||||
Net income (loss) | (90,355) | ||||||
Balances at Jun. 30, 2023 | 499,574 | $ 4 | 639,066 | (1,625) | (137,871) | 0 | |
Balances, shares at Jun. 30, 2023 | 647,500 | 42,735,304 | |||||
Balances at Mar. 31, 2023 | 485,649 | $ 4 | 592,544 | (1,242) | (105,657) | 0 | |
Balances, shares at Mar. 31, 2023 | 647,500 | 39,343,601 | |||||
Net issuance of common stock under equity-based compensation plans | (214) | (214) | |||||
Net issuance of common stock under equity-based compensation plans, shares | 81,703 | ||||||
Equity-based compensation | 7,920 | 7,920 | |||||
Unrealized gain (loss) on investments | (383) | (383) | |||||
Issuance of common stock | 38,388 | 38,388 | |||||
Issuance of common stock, shares | 3,310,000 | ||||||
Net income (loss) | (32,214) | (32,214) | |||||
Balances at Jun. 30, 2023 | $ 499,574 | $ 4 | $ 639,066 | $ (1,625) | $ (137,871) | $ 0 | |
Balances, shares at Jun. 30, 2023 | 647,500 | 42,735,304 |
CONSOLIDATED STATEMENTS OF CASH
CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 6 Months Ended | |
Jun. 30, 2023 | Jun. 30, 2022 | |
Operating activities: | ||
Net income (loss) | $ (90,355) | $ 161,173 |
Adjustments to reconcile net income (loss) to net cash used in operating activities: | ||
Equity-based compensation expense | 15,179 | 15,173 |
Amortization accretion on marketable securities | (3,516) | 1,737 |
Depreciation and amortization | 153 | 25 |
Non Cash Contributions From Noncontrolling Interests | 4 | 139 |
Gain on sale of Cullinan Pearl | 0 | (276,785) |
Realized loss on marketable securities | 0 | 109 |
Changes in operating assets and liabilities: | ||
Prepaid expenses and other current assets | 1,161 | (1,050) |
Accounts payable | (169) | (70) |
Accrued expenses and other current liabilities | (178) | 5,719 |
Income tax payable | (4,282) | 46,502 |
Net cash used in operating activities | (82,003) | (47,328) |
Investing activities: | ||
Proceeds from sales and maturities of marketable securities | 198,094 | 158,933 |
Purchase of marketable securities | (170,592) | (93,370) |
Purchase of property and equipment | (208) | 0 |
Proceeds from sale of Cullinan Pearl, net of escrow of $5,000 and cash transferred with sale of $2,898 | 0 | 270,000 |
Net cash provided by (used in) investing activities | 27,294 | 335,563 |
Financing activities: | ||
Proceeds from issuance of common stock | 38,388 | 0 |
Proceeds from issuance of convertible notes | 1,825 | 2,200 |
Proceeds from net issuance of common stock under equity-based compensation plans | 178 | 4,401 |
Repayment of convertible note | 0 | (2,200) |
Contributions From Noncontrolling Interests | 0 | 1,153 |
Net cash provided by financing activities | 40,391 | 5,554 |
Net increase (decrease) in cash and cash equivalents | (14,318) | 293,789 |
Cash and cash equivalents at beginning of period | 156,152 | 59,774 |
Cash and cash equivalents at end of period | 141,834 | 353,563 |
Non-cash financing activities and supplemental cash flow information | ||
Conversion Of Convertible Note Into Noncontrolling Interest | 175 | 0 |
Cash paid for income taxes | $ 4,708 | $ 0 |
CONSOLIDATED STATEMENTS OF CA_2
CONSOLIDATED STATEMENTS OF CASH FLOWS (Parenthetical) $ in Thousands | 6 Months Ended |
Jun. 30, 2023 USD ($) | |
Statement of Cash Flows [Abstract] | |
net of cash transferred | $ 2,898 |
Net of escrow | $ 5,000 |
Nature of Business and Basis of
Nature of Business and Basis of Presentation | 6 Months Ended |
Jun. 30, 2023 | |
Organization, Consolidation and Presentation of Financial Statements [Abstract] | |
Nature of Business and Basis of Presentation | (1) Nature of Business and Basis of Presentation Organization Cullinan Oncology, Inc., together with its consolidated subsidiaries ("Cullinan" or the "Company"), is a clinical-stage biopharmaceutical company focused on modality-agnostic targeted oncology that was incorporated in September 2016 and has a principal place of business in Cambridge, Massachusetts. Liquidity The Company has incurred significant operating losses, with the exception of 2022, and negative cash flows from operations since its inception and expects to continue to generate operating losses for the foreseeable future. Cullinan’s ultimate success depends on the outcome of its research and development activities as well as the ability to commercialize the Company’s product candidates. Cullinan is subject to a number of risks including, but not limited to, the need to obtain adequate additional funding for the ongoing and planned clinical development of its product candidates. Due to the numerous risks and uncertainties associated with pharmaceutical products and development, the Company is unable to accurately predict the timing or amount of funds required to complete development of its product candidates, and costs could exceed Cullinan’s expectations for a number of reasons, including reasons beyond the Company’s control. Since inception, Cullinan has funded its operations primarily through the sale of equity securities and from licensing or selling the rights to its product candidates. The Company expects that its cash, cash equivalents and short-term investments of $ 491.8 million and long-term investments and interest receivable of $ 20.3 million as of June 30, 2023, will be sufficient to fund its operating expenses and capital expenditure requirements through at least twelve months from the date of issuance of these unaudited consolidated financial statements. Interest receivable is included in prepaid expenses and other current assets on the consolidated balance sheets and represents accrued and unpaid interest on Cullinan's marketable securities. |
Summary of Significant Accounti
Summary of Significant Accounting Policies | 6 Months Ended |
Jun. 30, 2023 | |
Accounting Policies [Abstract] | |
Summary of Significant Accounting Policies | (2) Summary of Significant Accounting Policies Cullinan’s significant accounting policies have not changed materially from those disclosed in its annual audited consolidated financial statements and accompanying notes in its Annual Report on Form 10-K for the fiscal year ended December 31, 2022 (the “2022 10-K”), except for its accounting policy for equity-based compensation. Basis of Presentation The unaudited consolidated financial statements of the Company have been prepared in conformity with accounting principles generally accepted in the United States ("U.S. GAAP") and in accordance with applicable rules and regulations of the Securities Exchange Commission (the "SEC") for interim financial reporting and include the accounts of the Company and its consolidated subsidiaries. Cullinan considers consolidation of entities over which control is achieved by means other than voting rights. Intercompany balances and transactions have been eliminated in consolidation. The Company operates as one segment, which is developing early-stage cancer therapeutics. In the opinion of Cullinan’s management, the unaudited consolidated financial statements reflect all adjustments, which are normal and recurring in nature, and necessary for fair financial statement presentation. The preparation of these unaudited consolidated financial statements and accompanying notes in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the amounts reported. Actual results could differ materially from those estimates. These unaudited consolidated financial statements and accompanying notes should be read in conjunction with the Company’s annual audited consolidated financial statements and accompanying notes included in the 2022 10-K. Equity-Based Compensation The fair value of equity-based awards is measured at the grant date and is recognized as expense over the requisite service period, which is generally the vesting period. Forfeitures are recognized as they occur. Cullinan classifies equity-based compensation in its consolidated statements of operations and comprehensive income (loss) in the same manner in which the award recipient’s payroll costs or service payments are classified. The fair value of service-based restricted stock units ("RSUs") is the closing market price of the Company's common stock on the grant date. Cullinan measures the fair value of market-based RSUs on the grant date using a Monte Carlo simulation model. The Company estimates the fair value of stock options using the Black-Scholes option pricing model. Both the Monte Carlo simulation model and the Black-Scholes option pricing model require the input of objective and subjective assumptions. Certain assumptions used, including Cullinan's expected stock price volatility, involve inherent uncertainties and the application of management’s judgment. As a result, if factors change and management uses different assumptions, equity-based compensation expense could be materially different for future awards. Prior to 2023, the expected volatility used in the Black-Scholes option pricing model for new options was based on historical volatilities of the stock prices of similar entities within the Company’s industry over a period of time commensurate with the expected term assumption. In 2023, Cullinan determined that a sufficient amount of historical information was available regarding the volatility of its stock price to begin using a blended rate that combines the Company's historical volatility with the historical volatilities of the stock prices of similar entities within the Company’s industry over a period of time commensurate with the expected term assumption. Recently Issued Accounting Pronouncements There are no recently issued accounting pronouncements that will have a material impact on Cullinan's consolidated financial statements. |
Sale of Cullinan Pearl and Co-D
Sale of Cullinan Pearl and Co-Development Agreement with Taiho | 6 Months Ended |
Jun. 30, 2023 | |
Debt Securities, Available-for-Sale [Abstract] | |
Sale of Cullinan Pearl and Co-Development Agreement with Taiho | (3) Sale of Cullinan Pearl In June 2022, the Company sold its equity interest in its partially owned-subsidiary, Cullinan Pearl Corp. ("Cullinan Pearl"), which had worldwide rights to zipalertinib, excluding Japan, mainland China, Hong Kong, Macau, and Taiwan , to Taiho Pharmaceutical Co., Ltd ("Taiho") for an upfront payment of $ 275.0 million, with an increase to the purchase price in the amount of $ 2.9 million for cash held by Cullinan Pearl that was transferred with the sale. As of June 30, 2022, $ 5.0 million of the upfront payment was held in escrow. The escrow amount was released to Cullinan in the third quarter of 2022 once the Company and Taiho determined that no post-sale net working capital adjustment was necessary. Pursuant to the share purchase agreement with Taiho, Cullinan is also eligible to receive an additional $ 130.0 million tied to epidermal growth factor receptor exon20 non-small-cell lung cancer regulatory milestones. The Company concluded the transaction was a sale of non-financial assets, which were comprised mainly of intellectual property rights and related intangible assets, and that it transferred control of the non-financial assets at the closing of the sale. Cullinan recognized a gain on sale of Cullinan Pearl of $ 276.8 million within income from operations in its consolidated statement of operations and other comprehensive income (loss) for the three and six months ended June 30, 2022. The table below sets forth the book value of the Cullinan Pearl assets and liabilities sold along with the calculation of the gain on sale based on the cash consideration received. (in thousands) Book value of assets sold Cash $ 2,898 Prepaid expenses and other current assets 619 Amounts attributable to assets sold 3,517 Book value of liabilities sold Accrued expenses and other current liabilities 2,404 Amounts attributable to liabilities sold 2,404 Total identifiable net assets sold 1,113 Upfront consideration, inclusive of escrow of $ 5,000 and cash transferred of $ 2,898 277,898 Gain on sale of Cullinan Pearl $ 276,785 During the six months ended June 30, 2022, Cullinan Pearl issued $ 2.2 million of convertible notes to an affiliate of Taiho. The Company repaid these convertible notes at the closing of the Cullinan Pearl sale. |
Financial Instruments
Financial Instruments | 6 Months Ended |
Jun. 30, 2023 | |
Financial Instruments Pledged as Collateral [Abstract] | |
Financial Instruments | (4) Financial Instruments Investments Cullinan recognized its short-term and long-term investments by security type at June 30, 2023 as follows: Amortized Gross Gross Estimated (in thousands) Short-term investments Corporate notes $ 202,320 $ — $ ( 1,113 ) $ 201,207 U.S. government notes 74,708 3 ( 86 ) 74,625 Asset-backed securities 74,434 — ( 302 ) 74,132 Total short-term investments 351,462 3 ( 1,501 ) 349,964 Long-term investments Corporate notes 18,758 — ( 127 ) 18,631 Total long-term investments 18,758 — ( 127 ) 18,631 Total investments $ 370,220 $ 3 $ ( 1,628 ) $ 368,595 The Company recognized its short-term and long-term investments by security type at December 31, 2022 as follows: Amortized Gross Gross Estimated (in thousands) Short-term investments Corporate notes $ 244,498 $ 11 $ ( 1,743 ) $ 242,766 U.S. government notes 34,029 — ( 290 ) 33,739 Commercial paper 18,035 3 ( 13 ) 18,025 Asset-backed securities 16,625 — ( 15 ) 16,610 Total short-term investments 313,187 14 ( 2,061 ) 311,140 Long-term investments Corporate notes 81,436 18 ( 572 ) 80,882 Total long-term investments 81,436 18 ( 572 ) 80,882 Total investments $ 394,623 $ 32 $ ( 2,633 ) $ 392,022 Fair Value of Financial Instruments The following table sets forth the fair value of Cullinan’s financial assets that were measured at fair value on a recurring basis as of June 30, 2023: Level 1 Level 2 Level 3 Total (in thousands) Short-term investments Corporate notes $ — $ 201,207 $ — $ 201,207 U.S. government notes — 74,625 — 74,625 Asset-backed securities — 74,132 — 74,132 Total short-term investments — 349,964 — 349,964 Long-term investments Corporate notes — 18,631 — 18,631 Total long-term investments — 18,631 — 18,631 Total investments $ — $ 368,595 $ — $ 368,595 The following table sets forth the fair value of the Company’s financial assets that were measured at fair value on a recurring basis as of December 31, 2022: Level 1 Level 2 Level 3 Total (in thousands) Short-term investments Corporate notes $ — $ 242,766 $ — $ 242,766 U.S. government notes — 33,739 — 33,739 Commercial paper — 18,025 — 18,025 Asset-backed securities — 16,610 — 16,610 Total short-term investments — 311,140 — 311,140 Long-term investments Corporate notes — 80,882 — 80,882 Total long-term investments — 80,882 — 80,882 Total investments $ — $ 392,022 $ — $ 392,022 As of June 30, 2023 and December 31, 2022, the fair values of Cullinan's cash and cash equivalents, prepaid expenses and other current assets, accounts payable, accrued expenses and other current liabilities approximated their carrying values due to the short-term nature of these instruments. |
Accrued Expenses and Other Curr
Accrued Expenses and Other Current Liabilities | 6 Months Ended |
Jun. 30, 2023 | |
Accrued Expenses And Other Current Liabilities [Abstract] | |
Accrued Expenses and Other Current Liabilities | (5) Accrued Expenses and Other Current Liabilities Accrued expenses and other current liabilities consisted of the following as of June 30, 2023 and December 31, 2022: June 30, 2023 December 31, 2022 (in thousands) Accrued research and development expenses $ 6,130 $ 7,486 Due to Taiho under collaboration agreement, net 3,378 — Accrued bonus 3,108 4,516 Convertible note and accrued interest 1,885 178 Other current liabilities 1,030 1,955 Total accrued expenses and other current liabilities $ 15,531 $ 14,135 |
License and Collaboration Agree
License and Collaboration Agreements | 6 Months Ended |
Jun. 30, 2023 | |
License And Collaboration Agreements [Abstract] | |
License and Collaboration Agreements | (6) License and Collaboration Agreements Harbour License Agreement In February 2023, the Company and Harbour BioMed US Inc. (“Harbour”) entered into a license and collaboration agreement (the “Harbour License Agreement”), pursuant to which Harbour granted to Cullinan an exclusive license for the development, manufacturing and commercialization of HBM7008 (CLN-418) in the U.S. Under the terms of the Harbour License Agreement, the Company paid Harbour an upfront license fee of $ 25.0 million at signing. Harbour will be eligible to receive up to $ 148.0 million in milestone payments based on the achievement of pre-specified development and regulatory milestones. Harbour is also eligible to receive up to an additional $ 415.0 million in sales-based milestones as well as tiered royalties up to the high teens on a licensed product-by-licensed product basis, as a percentage of U.S. commercial sales. In addition, under the Harbour License Agreement, Harbour granted Cullinan certain intellectual property rights to enable the Company to perform its obligations and exercise its rights under the Harbour License Agreement. Unless earlier terminated, the Harbour License Agreement will continue in effect until the expiration of Cullinan’s royalty obligations. The Harbour License Agreement may be terminated by either party for a material breach by the other party, subject to notice and cure provisions, or in the event of the other party’s insolvency. The Company may terminate the Harbour License Agreement for convenience by providing 90 days written notice to Harbour. In the Harbour License Agreement, each party made customary representations and warranties and agreed to customary covenants, including, without limitation, with respect to indemnification, for transactions of this type. Cullinan evaluated the Harbour License Agreement and determined that the exclusive license for the development, manufacturing and commercialization of HBM7008 (CLN-418) in the U.S represented an asset acquisition of in-process research and development. The Company also determined that the asset had no alternative future use at the time of acquisition, and therefore the upfront license fee of $ 25.0 million was recorded within research and development expenses during the six months ended June 30, 2023. Co-Development Agreement with Taiho In June 2022, Cullinan and an affiliate of Taiho entered into a co-development agreement, pursuant to which the Company will collaborate to develop zipalertinib and will retain the option to co-commercialize zipalertinib in the U.S. Under the co-development agreement, development costs for zipalertinib shall be shared equally between Taiho and Cullinan with each party receiving 50 % of any future pre-tax profits from potential U.S. sales of zipalertinib. The Company concluded that the co-development agreement with Taiho is a collaborative arrangement because Cullinan is an active participant in the development of zipalertinib. Payments made to or received from Taiho for zipalertinib development activities after the execution of the co-development agreement are recorded within research and development expenses. For the three and six months ended June 30, 2023, the Company recorded research and development expense of $ 5.5 million and $ 10.2 million, respectively, related to its share of costs incurred by Taiho. Cullinan incurred $ 2.1 million and $ 3.1 million of costs that were reimbursable by Taiho during the three and six months ended June 30, 2023, respectively, which were recorded as a reduction to research and development expenses. The net amount of $ 3.4 million due to Taiho was recorded within accrued expenses and other current liabilities as of June 30, 2023. Other License and Collaboration Expenses During the six months ended June 30, 2023, Cullinan recorded $ 0.2 million in research and development expenses relating to the license agreement with the Massachusetts Institute of Technology (the "MIT License Agreement") for CLN-617. During the three and six months ended June 30, 2022, the Company recorded $ 0.2 million in research and development expenses relating to the MIT License Agreement. During the six months ended June 30, 2022, Cullinan recorded $ 0.5 million in research and development expenses relating to a collaboration agreement with Adimab, LLC. |
Stockholders' Equity
Stockholders' Equity | 6 Months Ended |
Jun. 30, 2023 | |
Stockholders' Equity Note [Abstract] | |
Stockholders' Equity | (7) Stockholders' Equity Common Stock Each share of common stock entitles the holder to one vote and to receive dividends when and if declared by the board of directors of the Company. No dividends have been declared through June 30, 2023. At-the-Market Equity Offering Program In May 2023, Cullinan entered into an agreement with Cowen and Company, LLC (“Cowen”) to establish an at-the-market equity offering program (the “ATM") pursuant to which the Company may offer and sell up to $ 125.0 million of its common stock from time to time through Cowen, acting as its sales agent. In the three months ended June 30, 2023, the Company sold approximately 3.3 million shares under the ATM and received net proceeds of $ 38.4 million after deducting commissions. As of June 30, 2023, Cullinan had $ 85.6 million in shares of its common stock remaining under the ATM. Preferred Stock In January 2023, the Company entered into an exchange agreement with Biotechnology Value Fund, L.P., Biotechnology Value Fund II, L.P., Biotechnology Value Trading Fund OS LP and MSI BVF SPV, LLC (the “Stockholders”), pursuant to which the Stockholders exchanged 6.5 million shares of Cullinan’s common stock for 0.6 million shares of newly designated Series A convertible preferred stock, a “toothless” preferred stock, par value $ 0.0001 per share. Each share of the preferred stock will be convertible into ten shares of common stock at the option of the holder at any time, subject to certain limitations, including that the holder will be prohibited from converting preferred stock into common stock if, as a result of such conversion, the holder, together with its affiliates, would beneficially own a number of shares of common stock more than 9.99 % of the total common stock then issued and outstanding immediately following the conversion of such shares of preferred stock. Holders of the preferred stock are permitted to increase this percentage to an amount not to exceed 19.99 % upon 60 days notice. Shares of preferred stock will generally have no voting rights, except as required by law and except that the consent of a majority of the holders of the outstanding preferred stock will be required to amend the terms of the preferred stock. In the event of the Company’s liquidation, dissolution or winding up, holders of preferred stock will participate pari passu with any distribution of proceeds to holders of common stock. Holders of preferred stock are entitled to receive when, as, and if dividends are declared and paid on the common stock, an equivalent dividend, calculated on an as-converted basis. Shares of preferred stock are otherwise not entitled to dividends. The preferred stock ranks (i) senior to any class or series of capital stock of Cullinan hereafter created specifically ranking by its terms junior to the preferred stock; (ii) on parity with the common stock and any class or series of capital stock of the Company created specifically ranking by its terms on parity with the preferred stock; and (iii) junior to any class or series of capital stock of Cullinan created specifically ranking by its terms senior to any preferred stock, in each case, as to distributions of assets upon liquidation, dissolution or winding up of the Company, whether voluntarily or involuntarily. The Company evaluated the preferred stock for liability or equity classification. Cullinan determined that the preferred stock should be classified as permanent equity as it is not redeemable for cash or other assets (i) on a fixed or determinable date, (ii) at the option of the holder, or (iii) upon the occurrence of an event that is not solely within control of the Company. Noncontrolling Interests in Subsidiaries Certain subsidiaries issue common stock in connection with licensing agreements and to employees, directors and consultants pursuant to subsidiary equity incentive plans. The holders of subsidiary common stock are entitled to one vote per share. The holders of subsidiary common stock are entitled to receive dividends when and if declared by the subsidiaries’ board of directors and distributions in either case only after the payment of all preferential amounts required to be paid to the holders of shares of preferred stock of the respective subsidiary. Cullinan Amber As of June 30, 2023, the Company held common stock and Series A preferred stock that represented 94 % of Cullinan Amber Corp.’s ("Cullinan Amber") outstanding equity. As of June 30, 2023, noncontrolling interests collectively held common stock that represented 6 % of Cullinan Amber's outstanding equity. In each of the three and six months ended June 30, 2023, no losses were attributed to the noncontrolling interests of Cullinan Amber. In each of the three and six months ended June 30, 2022, $ 0.1 million of losses were attributed to the noncontrolling interests of Cullinan Amber. Cullinan Florentine As of June 30, 2023, Cullinan held common stock, Series A preferred stock and Series B preferred stock that represented 96 % of Cullinan Florentine Corp.'s ("Cullinan Florentine") outstanding equity. As of June 30, 2023, noncontrolling interests collectively held common stock that represented 4 % of Cullinan Florentine's outstanding equity. In each of the three and six months ended June 30, 2023 and 2022, no losses were attributed to the noncontrolling interests of Cullinan Florentine. Cullinan MICA As of June 30, 2023, Cullinan held common stock and Series A preferred stock that represented 96 % of Cullinan MICA Corp.'s ("Cullinan MICA") outstanding equity. As of June 30, 2023, noncontrolling interests collectively held common stock and Series A preferred stock that represented 4 % of Cullinan MICA's outstanding equity. In the three and six months ended June 30, 2023, no losses and $ 0.2 million of losses, respectively, were attributed to the noncontrolling interests of Cullinan MICA. In the three and six months ended June 30, 2022, $ 0.7 million and $ 1.1 million of losses, respectively, were attributed to the noncontrolling interests of Cullinan MICA. Cullinan Pearl In June 2022, the Company sold its equity interest in its partially-owned subsidiary, Cullinan Pearl, to Taiho. Refer to Note 3 for additional details relating to the transaction. In the three and six months ended June 30, 2022, no losses and $ 0.3 million of losses, respectively, were attributed to the noncontrolling interests of Cullinan Pearl. |
Equity-Based Compensation
Equity-Based Compensation | 6 Months Ended |
Jun. 30, 2023 | |
Share-Based Payment Arrangement [Abstract] | |
Equity-Based Compensation | (8) Equity-Based Compensation Cullinan recorded equity-based compensation in the following expense categories in the consolidated statements of operations and comprehensive income (loss) for the three and six months ended June 30, 2023 and 2022: Three Months Ended June 30, Six Months Ended June 30, 2023 2022 2023 2022 (in thousands) Research and development $ 3,249 $ 4,379 $ 6,303 $ 7,039 General and administrative 4,671 4,229 8,876 8,134 Total equity-based compensation $ 7,920 $ 8,608 $ 15,179 $ 15,173 Determining Fair Value of Options The fair value of options is estimated using the Black-Scholes option pricing model, which takes into account inputs such as the exercise price, the value of the underlying common stock at the grant date, expected term, expected volatility, risk-free interest rate and dividend yield. The fair value of each grant of options during the six months ended June 30, 2023 and 2022 were determined using the methods and assumptions discussed below: • The expected term of options is determined using the “simplified” method, as prescribed in the SEC Staff Accounting Bulletin No. 107, whereby the expected life equals the arithmetic average of the vesting term and the original contractual term of the option due to the Company’s lack of sufficient historical data. • The risk-free interest rate is based on implied yields available from U.S. Treasury securities with a remaining term equal to the expected term assumed at the grant date. • Prior to 2023, the expected volatility used in the Black-Scholes option pricing model for new options was based on historical volatilities of the stock prices of similar entities within Cullinan’s industry over a period of time commensurate with the expected term assumption. In 2023, the Company determined that a sufficient amount of historical information was available regarding the volatility of its stock price to begin using a blended rate that combines its historical volatility with the historical volatilities of the stock prices of similar entities within Cullinan’s industry over a period of time commensurate with the expected term assumption. • The estimated annual dividend yield was based on the Company’s expectation of not paying dividends on its common stock in the foreseeable future. The grant date fair value was estimated at the time of grant using the Black-Scholes option-pricing model using the following weighted-average assumptions in the six months ended June 30, 2023 and 2022: Six Months Ended June 30, 2023 2022 Risk-free interest rate 3.9 % 2.2 % Expected term (in years) 6.0 6.0 Expected volatility 79.1 % 78.8 % Expected dividend yield 0.0 % 0.0 % |
Related Party Transactions
Related Party Transactions | 6 Months Ended |
Jun. 30, 2023 | |
Related Party Transactions [Abstract] | |
Related Party Transactions | (9) Related Party Transactions Royalty Transfer Agreements Cullinan Amber, Cullinan Florentine and Cullinan MICA are each party to royalty transfer agreements with MPM Oncology Charitable Foundation, Inc. and UBS Optimus Foundation (together, the "Foundations"). Under each of these respective agreements, the Foundations are collectively entitled to receive a low single digit royalty percentage of all global net sales of any products developed by the applicable subsidiary, subject to limitations after patent expirations and on intellectual property developed after a change of control. Cullinan has deemed these royalty transfer agreements to be freestanding financial instruments that should be accounted for at fair value. The Company concluded that these instruments had no value at the inception of the agreements. Cullinan has not had any applicable net sales from its products and as a result, has no t paid or incurred any royalties under these agreements as of June 30, 2023. Given the early-stage nature of the underlying technologies and inherent technical, regulatory and competitive risks associated with achieving approval and commercialization, the Company ascribed no value to the royalty transfer agreements as of June 30, 2023 and December 31, 2022. |
Income Taxes
Income Taxes | 6 Months Ended |
Jun. 30, 2023 | |
Income Tax Disclosure [Abstract] | |
Income Taxes | (10) Income Taxes During each of the three and six months ended June 30, 2023, Cullinan did no t record an income tax expense or benefit. During the three and six months ended June 30, 2022, the Company recorded an income tax provision of $ 66.1 million and $ 46.5 million, respectively. The tax provision recorded for the period ended June 30, 2022 was driven by the expected tax from the gain on sale of Cullinan Pearl, partially offset by the release of valuation allowance for the expected utilization of certain historical tax attributes against the gain from the sale. Refer to Note 3 for additional details on the sale of Cullinan's equity interest in Cullinan Pearl. The Company has evaluated the positive and negative evidence bearing upon its ability to realize its deferred tax assets, which primarily consist of capitalized research and development costs, temporary differences on equity-based compensation, and net operating loss carryforwards. Cullinan has considered its history of cumulative net losses and its estimated future taxable income and has concluded that it is more likely than not that the Company will not realize the benefits of its deferred tax assets. As a result, Cullinan has maintained a full valuation allowance against its remaining net deferred tax assets as of June 30, 2023. |
Commitments and Contingencies
Commitments and Contingencies | 6 Months Ended |
Jun. 30, 2023 | |
Commitments and Contingencies Disclosure [Abstract] | |
Commitments and Contingencies | (11) Commitments and Contingencies The Company enters into contracts in the normal course of business with contract research organizations, contract manufacturing organizations, and other third parties for preclinical research studies, clinical trials and testing and manufacturing services. These agreements generally include cancellation clauses. Indemnification Agreements In the ordinary course of business, Cullinan may provide indemnification of varying scope and terms to vendors, lessors, business partners and other parties with respect to certain matters including, but not limited to, losses arising out of breach of such agreements or from intellectual property infringement claims made by third parties. In addition, the Company has entered into indemnification agreements with members of its board of directors and executive officers that will require Cullinan, among other things, to indemnify them against certain liabilities that may arise by reason of their status or service as directors or officers. The maximum potential amount of future payments the Company could be required to make under these indemnification agreements is, in certain cases, unlimited. To date, Cullinan has not incurred any material costs as a result of such indemnifications. The Company is not aware of any indemnification arrangements that could have a material effect on its financial position, results of operations or cash flows, and it has no t accrued any liabilities related to such obligations in its consolidated financial statements as of June 30, 2023 and December 31, 2022. Legal Proceedings Cullinan is not currently party to or aware of any material legal proceedings. At each reporting date, the Company evaluates whether or not a potential loss amount or a potential range of loss is probable and reasonably estimable under the provisions of the authoritative guidance that addresses accounting for contingencies. Cullinan expenses as incurred the costs related to such legal proceedings. |
Leases
Leases | 6 Months Ended |
Jun. 30, 2023 | |
Leases [Abstract] | |
Leases | (12) Leases The Company has an operating lease for approximately 8,000 square feet of office space in a multi-tenant building in Cambridge, Massachusetts, which commenced in February 2018 and goes through June 2024 (the "Suite 520 Lease") . In August 2022, Cullinan entered into an additional operating lease for approximately 14,000 square feet of office space in a multi-tenant building in Cambridge, Massachusetts through July 2026. Lease expense consisted of operating lease costs of $ 0.4 million and $ 0.9 million for the three and six months ended June 30, 2023, respectively. Lease expense consisted of operating lease costs of $ 0.1 million and $ 0.3 million for the three and six months ended June 30, 2022, respectively. The following table summarizes supplemental cash flow information for the six months ended June 30, 2023 and 2022: Six Months Ended June 30, 2023 2022 (in thousands) Cash paid for amounts included in measurement of lease liabilities: Operating cash flows from operating leases $ 875 $ 303 Right-of-use asset obtained in exchange for an operating lease liability $ — $ 1,311 The following table summarizes the Company’s future minimum lease payments and reconciliation of lease liabilities as of June 30, 2023: June 30, 2023 (in thousands) Remainder of 2023 $ 1,006 2024 1,738 2025 1,461 2026 872 Total future minimum lease payments 5,077 Less: imputed interest ( 691 ) Total lease liabilities at present value $ 4,386 The following table summarizes the weighted-average remaining lease term and discount rate as of June 30, 2023 and December 31, 2022: June 30, 2023 December 31, 2022 Weighted-average remaining lease term (in years) 2.8 3.2 Weighted-average discount rate 10.8 % 10.8 % As Cullinan’s operating leases did not provide an implicit rate, the Company used its incremental borrowing rate based on the information available in determining the present value of lease payments. Cullinan’s incremental borrowing rate was based on the term of the lease, the economic environment and reflects the rate the Company would have had to pay to borrow on a secured basis. Sublease Agreement In September 2022, Cullinan entered into a sublease agreement through May 2024 for the Suite 520 Lease. For the three and six months ended June 30, 2023, the Company recorded sublease income of $ 0.1 million and $ 0.3 million, respectively, within other income (expense), net. |
Net Income (Loss) per Share
Net Income (Loss) per Share | 6 Months Ended |
Jun. 30, 2023 | |
Earnings Per Share [Abstract] | |
Net Income (Loss) per Share | (13) Net Income (Loss) per Share The following table sets forth the calculation of basic and diluted net income (loss) per share for the three and six months ended June 30, 2023 and 2022: Three Months Ended June 30, Six Months Ended June 30, 2023 2022 2023 2022 (in thousands, except per share data) Numerator: Net income (loss) attributable to common stockholders of Cullinan $ ( 32,214 ) $ 174,898 $ ( 90,176 ) $ 162,800 Denominator: Weighted-average common stock outstanding - basic 39,952 44,873 40,315 44,654 Dilutive effect of common stock issuable from assumed exercise of equity awards — 1,508 — 1,735 Weighted-average common stock outstanding - diluted 39,952 46,381 40,315 46,389 Net income (loss) per share: Basic $ ( 0.82 ) $ 3.90 $ ( 2.24 ) $ 3.65 Diluted $ ( 0.82 ) $ 3.77 $ ( 2.24 ) $ 3.51 Cullinan used the treasury stock and if-converted methods to determine the number of dilutive shares. The following table sets forth potential common shares that were excluded from the computation of diluted net income (loss) per share for the six months ended June 30, 2023 and 2022 because their effect would have been anti-dilutive: Six Months Ended June 30, 2023 2022 (in thousands) Stock options 9,185 6,250 Preferred stock 5,795 — Restricted stock awards and RSUs 156 — Total 15,136 6,250 |
Summary of Significant Accoun_2
Summary of Significant Accounting Policies (Policies) | 6 Months Ended |
Jun. 30, 2023 | |
Accounting Policies [Abstract] | |
Basis of Presentation | Basis of Presentation The unaudited consolidated financial statements of the Company have been prepared in conformity with accounting principles generally accepted in the United States ("U.S. GAAP") and in accordance with applicable rules and regulations of the Securities Exchange Commission (the "SEC") for interim financial reporting and include the accounts of the Company and its consolidated subsidiaries. Cullinan considers consolidation of entities over which control is achieved by means other than voting rights. Intercompany balances and transactions have been eliminated in consolidation. The Company operates as one segment, which is developing early-stage cancer therapeutics. In the opinion of Cullinan’s management, the unaudited consolidated financial statements reflect all adjustments, which are normal and recurring in nature, and necessary for fair financial statement presentation. The preparation of these unaudited consolidated financial statements and accompanying notes in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the amounts reported. Actual results could differ materially from those estimates. These unaudited consolidated financial statements and accompanying notes should be read in conjunction with the Company’s annual audited consolidated financial statements and accompanying notes included in the 2022 10-K. |
Equity-based Compensation | Equity-Based Compensation The fair value of equity-based awards is measured at the grant date and is recognized as expense over the requisite service period, which is generally the vesting period. Forfeitures are recognized as they occur. Cullinan classifies equity-based compensation in its consolidated statements of operations and comprehensive income (loss) in the same manner in which the award recipient’s payroll costs or service payments are classified. The fair value of service-based restricted stock units ("RSUs") is the closing market price of the Company's common stock on the grant date. Cullinan measures the fair value of market-based RSUs on the grant date using a Monte Carlo simulation model. The Company estimates the fair value of stock options using the Black-Scholes option pricing model. Both the Monte Carlo simulation model and the Black-Scholes option pricing model require the input of objective and subjective assumptions. Certain assumptions used, including Cullinan's expected stock price volatility, involve inherent uncertainties and the application of management’s judgment. As a result, if factors change and management uses different assumptions, equity-based compensation expense could be materially different for future awards. Prior to 2023, the expected volatility used in the Black-Scholes option pricing model for new options was based on historical volatilities of the stock prices of similar entities within the Company’s industry over a period of time commensurate with the expected term assumption. In 2023, Cullinan determined that a sufficient amount of historical information was available regarding the volatility of its stock price to begin using a blended rate that combines the Company's historical volatility with the historical volatilities of the stock prices of similar entities within the Company’s industry over a period of time commensurate with the expected term assumption. |
Recently Adopted Accounting Pronouncements | Recently Issued Accounting Pronouncements There are no recently issued accounting pronouncements that will have a material impact on Cullinan's consolidated financial statements. |
Sale of Cullinan Pearl and Co_2
Sale of Cullinan Pearl and Co-Development Agreement with Taiho (Tables) | 6 Months Ended |
Jun. 30, 2023 | |
Debt Securities, Available-for-Sale [Abstract] | |
Schedule of cash consideration received | (in thousands) Book value of assets sold Cash $ 2,898 Prepaid expenses and other current assets 619 Amounts attributable to assets sold 3,517 Book value of liabilities sold Accrued expenses and other current liabilities 2,404 Amounts attributable to liabilities sold 2,404 Total identifiable net assets sold 1,113 Upfront consideration, inclusive of escrow of $ 5,000 and cash transferred of $ 2,898 277,898 Gain on sale of Cullinan Pearl $ 276,785 |
Financial Instruments (Tables)
Financial Instruments (Tables) | 6 Months Ended |
Jun. 30, 2023 | |
Financial Instruments Pledged as Collateral [Abstract] | |
Schedule of Short-term and Long-term Investment Marketable Securities by Security Type | Investments Cullinan recognized its short-term and long-term investments by security type at June 30, 2023 as follows: Amortized Gross Gross Estimated (in thousands) Short-term investments Corporate notes $ 202,320 $ — $ ( 1,113 ) $ 201,207 U.S. government notes 74,708 3 ( 86 ) 74,625 Asset-backed securities 74,434 — ( 302 ) 74,132 Total short-term investments 351,462 3 ( 1,501 ) 349,964 Long-term investments Corporate notes 18,758 — ( 127 ) 18,631 Total long-term investments 18,758 — ( 127 ) 18,631 Total investments $ 370,220 $ 3 $ ( 1,628 ) $ 368,595 The Company recognized its short-term and long-term investments by security type at December 31, 2022 as follows: Amortized Gross Gross Estimated (in thousands) Short-term investments Corporate notes $ 244,498 $ 11 $ ( 1,743 ) $ 242,766 U.S. government notes 34,029 — ( 290 ) 33,739 Commercial paper 18,035 3 ( 13 ) 18,025 Asset-backed securities 16,625 — ( 15 ) 16,610 Total short-term investments 313,187 14 ( 2,061 ) 311,140 Long-term investments Corporate notes 81,436 18 ( 572 ) 80,882 Total long-term investments 81,436 18 ( 572 ) 80,882 Total investments $ 394,623 $ 32 $ ( 2,633 ) $ 392,022 |
Summary of Fair Value of Financial Assets Measured at Fair Value on a Recurring Basis | The following table sets forth the fair value of Cullinan’s financial assets that were measured at fair value on a recurring basis as of June 30, 2023: Level 1 Level 2 Level 3 Total (in thousands) Short-term investments Corporate notes $ — $ 201,207 $ — $ 201,207 U.S. government notes — 74,625 — 74,625 Asset-backed securities — 74,132 — 74,132 Total short-term investments — 349,964 — 349,964 Long-term investments Corporate notes — 18,631 — 18,631 Total long-term investments — 18,631 — 18,631 Total investments $ — $ 368,595 $ — $ 368,595 The following table sets forth the fair value of the Company’s financial assets that were measured at fair value on a recurring basis as of December 31, 2022: Level 1 Level 2 Level 3 Total (in thousands) Short-term investments Corporate notes $ — $ 242,766 $ — $ 242,766 U.S. government notes — 33,739 — 33,739 Commercial paper — 18,025 — 18,025 Asset-backed securities — 16,610 — 16,610 Total short-term investments — 311,140 — 311,140 Long-term investments Corporate notes — 80,882 — 80,882 Total long-term investments — 80,882 — 80,882 Total investments $ — $ 392,022 $ — $ 392,022 As of June 30, 2023 and December 31, 2022, the fair values of Cullinan's cash and cash equivalents, prepaid expenses and other current assets, accounts payable, accrued expenses and other current liabilities approximated their carrying values due to the short-term nature of these instruments. |
Accrued Expenses and Other Cu_2
Accrued Expenses and Other Current Liabilities (Tables) | 6 Months Ended |
Jun. 30, 2023 | |
Accrued Expenses And Other Current Liabilities [Abstract] | |
Summary of Accrued Expenses and Other Current Liabilities | Accrued expenses and other current liabilities consisted of the following as of June 30, 2023 and December 31, 2022: June 30, 2023 December 31, 2022 (in thousands) Accrued research and development expenses $ 6,130 $ 7,486 Due to Taiho under collaboration agreement, net 3,378 — Accrued bonus 3,108 4,516 Convertible note and accrued interest 1,885 178 Other current liabilities 1,030 1,955 Total accrued expenses and other current liabilities $ 15,531 $ 14,135 |
Equity-Based Compensation (Tabl
Equity-Based Compensation (Tables) | 6 Months Ended |
Jun. 30, 2023 | |
Share-Based Payment Arrangement [Abstract] | |
Schedule of Equity-based Compensation Expense Categories In Consolidated Statements of Operations and Comprehensive Income (Loss) | Cullinan recorded equity-based compensation in the following expense categories in the consolidated statements of operations and comprehensive income (loss) for the three and six months ended June 30, 2023 and 2022: Three Months Ended June 30, Six Months Ended June 30, 2023 2022 2023 2022 (in thousands) Research and development $ 3,249 $ 4,379 $ 6,303 $ 7,039 General and administrative 4,671 4,229 8,876 8,134 Total equity-based compensation $ 7,920 $ 8,608 $ 15,179 $ 15,173 |
Schedule of Assumptions Used to Estimate Fair value of Market-Based RSUs Granted | The grant date fair value was estimated at the time of grant using the Black-Scholes option-pricing model using the following weighted-average assumptions in the six months ended June 30, 2023 and 2022: Six Months Ended June 30, 2023 2022 Risk-free interest rate 3.9 % 2.2 % Expected term (in years) 6.0 6.0 Expected volatility 79.1 % 78.8 % Expected dividend yield 0.0 % 0.0 % |
Leases (Tables)
Leases (Tables) | 6 Months Ended |
Jun. 30, 2023 | |
Leases [Abstract] | |
Supplemental Cash Flow Information Relating to Leases | The following table summarizes supplemental cash flow information for the six months ended June 30, 2023 and 2022: Six Months Ended June 30, 2023 2022 (in thousands) Cash paid for amounts included in measurement of lease liabilities: Operating cash flows from operating leases $ 875 $ 303 Right-of-use asset obtained in exchange for an operating lease liability $ — $ 1,311 |
Summarizes of future minimum lease payments | The following table summarizes the Company’s future minimum lease payments and reconciliation of lease liabilities as of June 30, 2023: June 30, 2023 (in thousands) Remainder of 2023 $ 1,006 2024 1,738 2025 1,461 2026 872 Total future minimum lease payments 5,077 Less: imputed interest ( 691 ) Total lease liabilities at present value $ 4,386 |
Summarizes Lease Term and Discount Rate | The following table summarizes the weighted-average remaining lease term and discount rate as of June 30, 2023 and December 31, 2022: June 30, 2023 December 31, 2022 Weighted-average remaining lease term (in years) 2.8 3.2 Weighted-average discount rate 10.8 % 10.8 % |
Net Income (Loss) per Share (Ta
Net Income (Loss) per Share (Tables) | 6 Months Ended |
Jun. 30, 2023 | |
Earnings Per Share [Abstract] | |
Summary of Calculation of Basic and Diluted Net Loss Per Share | The following table sets forth the calculation of basic and diluted net income (loss) per share for the three and six months ended June 30, 2023 and 2022: Three Months Ended June 30, Six Months Ended June 30, 2023 2022 2023 2022 (in thousands, except per share data) Numerator: Net income (loss) attributable to common stockholders of Cullinan $ ( 32,214 ) $ 174,898 $ ( 90,176 ) $ 162,800 Denominator: Weighted-average common stock outstanding - basic 39,952 44,873 40,315 44,654 Dilutive effect of common stock issuable from assumed exercise of equity awards — 1,508 — 1,735 Weighted-average common stock outstanding - diluted 39,952 46,381 40,315 46,389 Net income (loss) per share: Basic $ ( 0.82 ) $ 3.90 $ ( 2.24 ) $ 3.65 Diluted $ ( 0.82 ) $ 3.77 $ ( 2.24 ) $ 3.51 |
Summary of Outstanding Equity Instruments Excluded from Computation of Diluted Net Income (Loss) Per Share | The following table sets forth potential common shares that were excluded from the computation of diluted net income (loss) per share for the six months ended June 30, 2023 and 2022 because their effect would have been anti-dilutive: Six Months Ended June 30, 2023 2022 (in thousands) Stock options 9,185 6,250 Preferred stock 5,795 — Restricted stock awards and RSUs 156 — Total 15,136 6,250 |
Nature of Business and Basis _2
Nature of Business and Basis of Presentation - Additional Information (Details) $ in Millions | Jun. 30, 2023 USD ($) |
Nature Of Business And Basis Of Presentation [Line Items] | |
Long-term investments and interest receivables | $ 20.3 |
Cash, cash equivalents, short-term investments and long-term investments | $ 491.8 |
Summary of Significant Accoun_3
Summary of Significant Accounting Policies - Additional Information (Details) | 6 Months Ended |
Jun. 30, 2023 Segment | |
Accounting Policies [Abstract] | |
Number of operating segments | 1 |
Summary of Significant Accoun_4
Summary of Significant Accounting Policies - Supplemental Balance Sheet Information Related to Operating Leases (Details) - USD ($) $ in Thousands | Jun. 30, 2023 | Dec. 31, 2022 |
Operating lease right-of-use assets | $ 3,501 | $ 4,130 |
Operating lease liabilities, current | 1,652 | 1,421 |
Noncurrent portion of operating lease liabilities | $ 2,734 | $ 3,590 |
Reorganization and Reverse Stoc
Reorganization and Reverse Stock Split - Summary of LLC Units Previously Reported as Redeemable Preferred Units or Temporary Equity Converted Reclassified to Equity (Details) - USD ($) $ in Thousands | Jun. 30, 2023 | Mar. 31, 2023 | Dec. 31, 2022 | Jun. 30, 2022 | Mar. 31, 2022 | Dec. 31, 2021 |
Stockholders' Equity (Members' Deficit) | ||||||
Common Stock | $ 4 | $ 5 | ||||
Additional paid-in capital | 639,066 | 585,320 | ||||
Accumulated other comprehensive loss | (1,625) | (2,601) | ||||
Accumulated deficit | (137,871) | (47,695) | ||||
Total Cullinan Stockholders' Equity (Members' Deficit) | 499,574 | 535,029 | ||||
Non-controlling interests in subsidiaries | 0 | 0 | ||||
Total Stockholders' Equity (Members' Deficit) | $ 499,574 | $ 485,649 | $ 535,029 | $ 604,618 | $ 419,470 | $ 425,374 |
Sale of Cullinan Pearl and Co_3
Sale of Cullinan Pearl and Co-Development Agreement with Taiho - Additional Information (Details) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2022 | Jun. 30, 2023 | Jun. 30, 2022 | Jun. 30, 2023 | Jun. 30, 2022 | |
Defined Benefit Plan Disclosure [Line Items] | |||||
Repayment of convertible notes | $ 0 | $ 2,200 | |||
net of cash transferred | 2,898 | ||||
Gain on sale of Cullinan Pearl | $ 0 | $ (276,785) | 0 | (276,785) | |
Payment held in escrow | 5,000 | ||||
Research and development | 27,391 | 26,411 | 79,487 | 50,947 | |
Prepaid expenses and other current assets | 619 | 619 | |||
Pearl - Taiho | |||||
Defined Benefit Plan Disclosure [Line Items] | |||||
Repayment of convertible notes | 2,200 | ||||
net of cash transferred | $ 2,900 | ||||
Additional receive payments from the party | 130,000 | ||||
Receive upfront payment from party | 275,000 | ||||
Gain on sale of Cullinan Pearl | $ (276,800) | $ (276,800) | |||
Payment held in escrow | $ 5,000 | ||||
Percentage of profits from potential sales | 50% | ||||
Research and development | 2,100 | 3,100 | |||
Research and development expense related to share of costs | $ 5,500 | $ 10,200 |
Sale of Cullinan Pearl and Co_4
Sale of Cullinan Pearl and Co-Development Agreement with Taiho - Schedule of cash consideration received (Details) $ in Thousands | 6 Months Ended |
Jun. 30, 2023 USD ($) | |
Book Value of Asset Sold [Abstract] | |
Cash | $ 2,898 |
Prepaid expenses and other current assets | 619 |
Amounts attributable to assets sold | 3,517 |
Book Value Of Liability Sold [Abstract] | |
Accrued expenses and other current liabilities | 2,404 |
Amounts attributable to liabilities sold | 2,404 |
Total identifiable net assets sold | 1,113 |
Upfront consideration, inclusive of escrow of $5,000 and cash transferred of $2,898 | 277,898 |
Gain on sale of Cullinan Pearl | $ 276,785 |
Sale of Cullinan Pearl and Co_5
Sale of Cullinan Pearl and Co-Development Agreement with Taiho - Parenthetical (Details) $ in Thousands | 6 Months Ended |
Jun. 30, 2023 USD ($) | |
Debt Securities, Available-for-Sale [Abstract] | |
Payment held in escrow | $ 5,000 |
Upfront consideration, cash transferred | $ 2,898 |
Financial Instruments - Schedul
Financial Instruments - Schedule of Short-term and Long-term Investment Marketable Securities by Security Type (Details) - USD ($) $ in Thousands | Jun. 30, 2023 | Dec. 31, 2022 |
Available For Sale Securities Fair Value To Amortized Cost Basis [Line Items] | ||
Amortized Cost | $ 370,220 | $ 394,623 |
Gross Unrealized Gains | 3 | 32 |
Gross Unrealized Losses | (1,628) | (2,633) |
Estimated Fair Value | 368,595 | 392,022 |
Long Term Investment | ||
Available For Sale Securities Fair Value To Amortized Cost Basis [Line Items] | ||
Amortized Cost | 18,758 | 81,436 |
Gross Unrealized Gains | 0 | 18 |
Gross Unrealized Losses | (127) | (572) |
Estimated Fair Value | 18,631 | 80,882 |
Long Term Investment | Corporate Note Securities | ||
Available For Sale Securities Fair Value To Amortized Cost Basis [Line Items] | ||
Amortized Cost | 18,758 | 81,436 |
Gross Unrealized Gains | 0 | 18 |
Gross Unrealized Losses | (127) | (572) |
Estimated Fair Value | 18,631 | 80,882 |
Short Term Investments | ||
Available For Sale Securities Fair Value To Amortized Cost Basis [Line Items] | ||
Amortized Cost | 351,462 | 313,187 |
Gross Unrealized Gains | 3 | 14 |
Gross Unrealized Losses | (1,501) | (2,061) |
Estimated Fair Value | 349,964 | 311,140 |
Short Term Investments | U.S. Government Notes | ||
Available For Sale Securities Fair Value To Amortized Cost Basis [Line Items] | ||
Amortized Cost | 74,708 | 34,029 |
Gross Unrealized Gains | 3 | 0 |
Gross Unrealized Losses | (86) | (290) |
Estimated Fair Value | 74,625 | 33,739 |
Short Term Investments | Asset-backed Securities | ||
Available For Sale Securities Fair Value To Amortized Cost Basis [Line Items] | ||
Amortized Cost | 74,434 | 16,625 |
Gross Unrealized Gains | 0 | 0 |
Gross Unrealized Losses | (302) | (15) |
Estimated Fair Value | 74,132 | 16,610 |
Short Term Investments | Commercial Paper | ||
Available For Sale Securities Fair Value To Amortized Cost Basis [Line Items] | ||
Amortized Cost | 18,035 | |
Gross Unrealized Gains | 3 | |
Gross Unrealized Losses | (13) | |
Estimated Fair Value | 18,025 | |
Short Term Investments | Corporate Note Securities | ||
Available For Sale Securities Fair Value To Amortized Cost Basis [Line Items] | ||
Amortized Cost | 202,320 | 244,498 |
Gross Unrealized Gains | 0 | 11 |
Gross Unrealized Losses | (1,113) | (1,743) |
Estimated Fair Value | $ 201,207 | $ 242,766 |
Financial Instruments - Summary
Financial Instruments - Summary of Fair Value of Financial Assets Measured on Recurring Basis (Details) - Recurring - USD ($) $ in Thousands | Jun. 30, 2023 | Dec. 31, 2022 |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | $ 349,964 | $ 311,140 |
Total long-term investments | 18,631 | 80,882 |
Assets Fair Value Disclosure, Total | 368,595 | 392,022 |
Level 1 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 0 | 0 |
Total long-term investments | 0 | 0 |
Assets Fair Value Disclosure, Total | 0 | 0 |
Level 2 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 349,964 | 311,140 |
Total long-term investments | 18,631 | 80,882 |
Assets Fair Value Disclosure, Total | 368,595 | 392,022 |
Level 3 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 0 | 0 |
Total long-term investments | 0 | 0 |
Assets Fair Value Disclosure, Total | 0 | 0 |
U.S. Government Notes | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 74,625 | 33,739 |
U.S. Government Notes | Level 1 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 0 | |
U.S. Government Notes | Level 2 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 74,625 | 33,739 |
U.S. Government Notes | Level 3 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 0 | 0 |
Asset-backed Securities | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 16,610 | |
Total long-term investments | 74,132 | |
Asset-backed Securities | Level 1 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 0 | |
Total long-term investments | 0 | |
Asset-backed Securities | Level 2 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 16,610 | |
Total long-term investments | 74,132 | |
Asset-backed Securities | Level 3 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 0 | |
Total long-term investments | 0 | |
Commercial Paper | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 18,025 | |
Commercial Paper | Level 1 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 0 | |
Commercial Paper | Level 2 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 18,025 | |
Commercial Paper | Level 3 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 0 | |
Corporate Note Securities | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 18,631 | 242,766 |
Total long-term investments | 201,207 | 80,882 |
Corporate Note Securities | Level 1 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 0 | 0 |
Total long-term investments | 0 | 0 |
Corporate Note Securities | Level 2 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 18,631 | 242,766 |
Total long-term investments | 201,207 | 80,882 |
Corporate Note Securities | Level 3 | ||
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] | ||
Total short-term investments | 0 | 0 |
Total long-term investments | $ 0 | $ 0 |
Accrued Expenses and Other Cu_3
Accrued Expenses and Other Current Liabilities - Summary of Accrued Expenses and Other Current Liabilities (Details) - USD ($) $ in Thousands | Jun. 30, 2023 | Dec. 31, 2022 |
Accounts Payable and Accrued Liabilities, Current [Abstract] | ||
Accrued research and development expenses | $ 6,130 | $ 7,486 |
Due to Taiho under collaboration agreement, net | 3,378 | 0 |
Accrued bonus | 3,108 | 4,516 |
Convertible note and accrued interest | 1,885 | 178 |
Other current liabilities | 1,030 | 1,955 |
Total accrued expenses and other current liabilities | $ 15,531 | $ 14,135 |
License and Collaboration Agr_2
License and Collaboration Agreements - Additional Information (Details) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2022 | Jun. 30, 2023 | Jun. 30, 2022 | Jun. 30, 2023 | Jun. 30, 2022 | |
License And Collaboration Agreements [Line Items] | |||||
Accrued expenses and other current liabilities | $ 2,404 | $ 2,404 | |||
Research and development costs | 27,391 | $ 26,411 | 79,487 | $ 50,947 | |
Harbour License Agreement [Member] | |||||
License And Collaboration Agreements [Line Items] | |||||
Upfront license fee | 25,000 | ||||
Harbour BioMed US Inc. [Member] | Harbour License Agreement [Member] | |||||
License And Collaboration Agreements [Line Items] | |||||
Upfront license fee | 25,000 | ||||
Harbour BioMed US Inc. [Member] | Maximum | Harbour License Agreement [Member] | Achievement Based [Member] | |||||
License And Collaboration Agreements [Line Items] | |||||
Aggregate amount of milestone payment | 148,000 | ||||
Harbour BioMed US Inc. [Member] | Maximum | Harbour License Agreement [Member] | Sales Based [Member] | |||||
License And Collaboration Agreements [Line Items] | |||||
Aggregate amount of milestone payment | 415,000 | ||||
Pearl - Taiho | |||||
License And Collaboration Agreements [Line Items] | |||||
Percentage of profits from potential sales | 50% | ||||
Research and development expense related to share of costs | 5,500 | 10,200 | |||
Accrued expenses and other current liabilities | 3,400 | 3,400 | |||
Research and development costs | $ 2,100 | 3,100 | |||
Adimab | |||||
License And Collaboration Agreements [Line Items] | |||||
Research and development costs | 500 | ||||
MIT | |||||
License And Collaboration Agreements [Line Items] | |||||
Research and development costs | $ 200 | $ 200 | $ 200 |
Stockholders' Equity - Addition
Stockholders' Equity - Additional Information (Details) - USD ($) | 3 Months Ended | 6 Months Ended | ||||
Jun. 30, 2023 | Jun. 30, 2022 | Jun. 30, 2023 | Jun. 30, 2022 | Jan. 31, 2023 | Dec. 31, 2022 | |
Common Stock And Noncontrolling Interest In Subsidiaries [Line Items] | ||||||
Dividends declared | $ 0 | $ 0 | ||||
Common stock, voting rights | Each share of common stock entitles the holder to one vote and to receive dividends when and if declared by the board of directors of the Company. | |||||
Preferred Stock, Par or Stated Value Per Share | $ 0.0001 | $ 0.0001 | $ 0.0001 | |||
Number of shares of common stock, percentage | 9.99% | 9.99% | ||||
Increase in number of shares of preferred stock, percentage | 19.99% | 19.99% | ||||
Shares issued | 647,500 | 647,500 | 0 | |||
Shares sold/issued | 42,735,304 | 42,735,304 | 45,796,449 | |||
Losses attributed to noncontrolling interests | $ 0 | $ (833,000) | $ (179,000) | $ (1,627,000) | ||
Biotechnology Value Fund, L.P exchange agreement [Member] | ||||||
Common Stock And Noncontrolling Interest In Subsidiaries [Line Items] | ||||||
Newly designated Series A preferred stock | 600,000 | |||||
Preferred Stock, Par or Stated Value Per Share | $ 0.0001 | |||||
Number of common stock exchange | 6,500,000 | |||||
In May 2023 | ||||||
Common Stock And Noncontrolling Interest In Subsidiaries [Line Items] | ||||||
Offer and sell companys common stock | $ 125,000,000 | $ 125,000,000 | ||||
Common Stock | ||||||
Common Stock And Noncontrolling Interest In Subsidiaries [Line Items] | ||||||
Additional shares issued | 3,310,000 | |||||
At-the-Market Equity Offering Program | In May 2023 | ||||||
Common Stock And Noncontrolling Interest In Subsidiaries [Line Items] | ||||||
Net proceeds | $ 38,400,000 | |||||
Shares sold/issued | 3,300,000 | 3,300,000 | ||||
Treasury Stock, Common, Shares | 85,600,000 | 85,600,000 | ||||
Cullinan Amber Corp | ||||||
Common Stock And Noncontrolling Interest In Subsidiaries [Line Items] | ||||||
Losses attributed to noncontrolling interests | $ 0 | 100,000 | $ 0 | 100,000 | ||
Cullinan Amber Corp | Series A Preferred Stock | ||||||
Common Stock And Noncontrolling Interest In Subsidiaries [Line Items] | ||||||
Percentage of share purchased as part of asset acquisition | 94% | |||||
Ownership interest percentage | 6% | |||||
Cullinan Florentine Corp | Series A Preferred Stock | ||||||
Common Stock And Noncontrolling Interest In Subsidiaries [Line Items] | ||||||
Percentage of share purchased as part of asset acquisition | 96% | |||||
Ownership interest percentage | 4% | |||||
MICA | HLBV | ||||||
Common Stock And Noncontrolling Interest In Subsidiaries [Line Items] | ||||||
Losses attributed to noncontrolling interests | $ 0 | 700,000 | $ 200,000 | 1,100,000 | ||
MICA | Series A Preferred Stock | ||||||
Common Stock And Noncontrolling Interest In Subsidiaries [Line Items] | ||||||
Percentage of share purchased as part of asset acquisition | 96% | |||||
Cullinan Pearl Corp | HLBV | ||||||
Common Stock And Noncontrolling Interest In Subsidiaries [Line Items] | ||||||
Losses attributed to noncontrolling interests | $ 0 | $ 300,000 |
Equity-Based Compensation - Sch
Equity-Based Compensation - Schedule of Equity-based Compensation Expense Categories In Consolidated Statements of Operations and Comprehensive Income (Loss) (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2023 | Jun. 30, 2022 | Jun. 30, 2023 | Jun. 30, 2022 | |
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] | ||||
Total equity-based compensation | $ 7,920 | $ 8,608 | $ 15,179 | $ 15,173 |
Research and Development | ||||
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] | ||||
Total equity-based compensation | 3,249 | 4,379 | 6,303 | 7,039 |
General and Administrative | ||||
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] | ||||
Total equity-based compensation | $ 4,671 | $ 4,229 | $ 8,876 | $ 8,134 |
Equity-Based Compensation - S_2
Equity-Based Compensation - Schedule of Assumptions Used to Estimate Fair value of Market-Based RSUs Granted (Details) | 6 Months Ended | |
Jun. 30, 2023 | Jun. 30, 2022 | |
Share-Based Payment Arrangement, Recognized Amount [Abstract] | ||
Risk-free interest rate | 3.90% | 2.20% |
Expected term (in years) | 6 years | 6 years |
Expected volatility | 79.10% | 78.80% |
Expected dividend yield | 0% | 0% |
Related Party Transactions - Ad
Related Party Transactions - Additional Information (Details) $ in Thousands | 6 Months Ended |
Jun. 30, 2023 USD ($) | |
Related Party Transaction [Line Items] | |
Royalties under obligation | $ 0 |
Income Taxes - Additional Infor
Income Taxes - Additional Information (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2023 | Jun. 30, 2022 | Jun. 30, 2023 | Jun. 30, 2022 | |
Income Tax Disclosure [Abstract] | ||||
Income tax expense/(benefit) | $ 0 | $ (66,070) | $ 0 | $ (46,502) |
Income Tax Provision | $ 66,100 | $ 46,500 |
Commitment and Contingencies (A
Commitment and Contingencies (Additional Information) (Details) - USD ($) $ in Thousands | Jun. 30, 2023 | Dec. 31, 2022 |
Indemnification Agreement [Member] | ||
Loss Contingencies [Line Items] | ||
Accrued Liabilities | $ 0 | $ 0 |
Leases - Additional Information
Leases - Additional Information (Details) $ in Millions | 1 Months Ended | 3 Months Ended | 6 Months Ended | |||
Aug. 31, 2022 ft² | Dec. 31, 2017 ft² | Jun. 30, 2023 USD ($) | Mar. 31, 2022 USD ($) | Jun. 30, 2023 USD ($) | Jun. 30, 2022 USD ($) | |
Lessee Lease Description [Line Items] | ||||||
Operating Lease expense | $ 0.4 | $ 0.1 | $ 0.9 | $ 0.3 | ||
Sublease income | $ 0.1 | $ 0.3 | ||||
Operating lease commence date | Feb. 01, 2018 | |||||
Operating lease expiration date | Jun. 30, 2024 | |||||
Massachusetts | ||||||
Lessee Lease Description [Line Items] | ||||||
Operating lease rentable area | ft² | 14,000 | 8,000 |
Leases - Supplemental Cash Flow
Leases - Supplemental Cash Flow Information Relating to Leases (Details) - USD ($) $ in Thousands | 6 Months Ended | |
Jun. 30, 2023 | Jun. 30, 2022 | |
Leases [Abstract] | ||
Operating cash flows from operating leases | $ 875 | $ 303 |
Right-of-use asset obtained in exchange for an operating lease liability | $ 0 | $ 1,311 |
Leases - Summary of Future Mini
Leases - Summary of Future Minimum Payments Due Under Operating Lease (Details) $ in Thousands | Jun. 30, 2023 USD ($) |
Lessee, Operating Lease, Liability, to be Paid [Abstract] | |
Remainder of 2023 | $ 1,006 |
2024 | 1,738 |
2025 | 1,461 |
2026 | 872 |
Total future minimum lease payments | 5,077 |
Less: imputed interest | (691) |
Total lease liabilities at present value | $ 4,386 |
Leases - Summary of Weighted Av
Leases - Summary of Weighted Average Remaining Lease Terms and Discount Rates (Details) | Jun. 30, 2023 | Dec. 31, 2022 |
Leases [Abstract] | ||
Weighted-average remaining lease term (years) | 2 years 9 months 18 days | 3 years 2 months 12 days |
Weighted-average discount rate | 10.80% | 10.80% |
Net Income (Loss) per Share - S
Net Income (Loss) per Share - Summary of Calculation of Basic and Diluted Net Loss Per Share (Details) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2023 | Jun. 30, 2022 | Jun. 30, 2023 | Jun. 30, 2022 | |
Numerator: | ||||
Net loss attributable to common stockholders of Cullinan | $ (32,214) | $ 174,898 | $ (90,176) | $ 162,800 |
Denominator | ||||
Weighted-average common stock outstanding - basic | 39,952 | 44,873 | 40,315 | 44,654 |
Dilutive effect of common stock issuable from assumed exercise of equity awards | 0 | 1,508 | 0 | 1,735 |
Weighted-average common stock outstanding - diluted | 39,952 | 46,381 | 40,315 | 46,389 |
Net income (loss) per share: | ||||
Basic | $ (0.82) | $ 3.90 | $ (2.24) | $ 3.65 |
Diluted | $ (0.82) | $ 3.77 | $ (2.24) | $ 3.51 |
Net Income (Loss) per Share -_2
Net Income (Loss) per Share - Summary of Outstanding Equity Instruments Excluded from Computation of Diluted Net Loss Per Share (Details) - shares shares in Thousands | 6 Months Ended | |
Jun. 30, 2023 | Jun. 30, 2022 | |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] | ||
Shares excluded from computation of diluted net loss per share (in shares) | 15,136 | 6,250 |
Stock Options | ||
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] | ||
Shares excluded from computation of diluted net loss per share (in shares) | 9,185 | 6,250 |
Preferred Stock | ||
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] | ||
Shares excluded from computation of diluted net loss per share (in shares) | 5,795 | 0 |
Restricted Stock Awards and RSUs | ||
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] | ||
Shares excluded from computation of diluted net loss per share (in shares) | 156 | 0 |