January 22, 2020 John Goll Chief Accounting Officer INSMED Inc 10 Finderne Avenue, Building 10 Bridgewater, NJ. 08807 Re: INSMED Inc Form 10-K filed on February 22, 2019 Filed on February 22, 2019 Form 8-K filed on October 30, 2019 File no. 000-30739 Dear Mr. Goll: We have completed our review of your filings. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences