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                             April 29, 2020

       Robert Mattacchione
       Chief Executive Officer
       Novo Integrated Sciences, Inc.
       11120 NE 2nd Street, Suite 200
       Bellevue, Washington 98004

                                                        Re: Novo Integrated
Sciences, Inc.
                                                            Offering Statement
on Form 1-A
                                                            Filed April 2, 2020
                                                            File No. 024-11186

       Dear Mr. Mattacchione:

              We have reviewed your offering statement and have the following
comments. In some of
       our comments, we may ask you to provide us with information so we may
better understand your
       disclosure.

              Please respond to this letter by amending your offering statement
and providing the
       requested information. If you do not believe our comments apply to your
facts and
       circumstances or do not believe an amendment is appropriate, please tell
us why in your
       response. After reviewing any amendment to your offering statement and
the information you
       provide in response to these comments, we may have additional comments.

       Form 1-A filed April 2, 2020

       Summary, page 3

   1.                                                   Disclosure indicates
that Robert Mattacchione will continue to beneficially own over 50%
                                                        of your common stock
after this offering. Please add disclosure here highlighting that Mr.
                                                        Mattacchione will
continue to control corporate matters after this offering and add a risk
                                                        factor discussing any
resulting risks to the company and its stockholders.
       Item 6: Use of Proceeds to the Issuer, page 80

   2.                                                   Clarify your disclosure
to indicate whether your intended use of proceeds takes into
                                                        account the potential
impacts of COVID-19 that you describe on page 36.
 Robert Mattacchione
FirstName LastNameRobert Mattacchione
Novo Integrated Sciences, Inc.
Comapany NameNovo Integrated Sciences, Inc.
April 29, 2020
Page 29,
April 2 2020 Page 2
FirstName LastName
Business Growth Strategy, page 81

3.       You disclose a number of planned business initiatives and
opportunities in your business
         growth strategy section. Please revise to disclose the current
developmental status of
         these initiatives and opportunities, such as the concrete steps you
have taken to date,
         anticipated costs to complete their development, the sources of
funding for these
         anticipated costs and other remaining actions you have to take before
launch. For
         example, you include a significant amount of disclosure about your
planned CBD
         platform and your telemedicine platform, but it is unclear what stage
of development these
         platforms are in and when the platforms are expected to launch.
Item 9: Management's Discussion and Analysis of Financial Condition and Results
of Operations
, page 105

4.       You disclose on page 36 that as a result of COVID-19 you have closed
all corporate
         clinics effective March 17, 2020. In addition, you are significantly
reducing the
         engagement of your multi-disciplinary primary healthcare services and
products with your
         client patients as provided through contracted services with eldercare
facilities and your
         affiliate clinics. Please disclose more specifically how this has
impacted your operating
         results as compared to the historical periods that you present. That
is, clarify the extent to
         which your revenue has been reduced as a result of the closures and
reductions in service.
         Further, clarify how this has impacted your overall liquidity position
and outlook, and the
         course of action you are taking to remedy any liquidity deficiency.
Disclose your current
         working capital position and clarify whether you expect collectability
issues with your
         accounts receivable. Lastly, clarify any potential impacts on
impairment of long lived
         assets, intangible assets and goodwill. For additional guidance, refer
to the Division of
         Corporation Finance Disclosure Guidance Topic No. 9 issued March 25,
2020 and Item
         9(b) of Form 1-A.
5.       Clarify your disclosure to describe the potential impact that COVID-19
has on your ability
         to execute your license and joint venture agreements as planned, as
well as the other
         business growth initiatives that you disclose.
Where You Can Find More Information, page 133

6.       You disclose here certain reporting requirements for issuers of Tier
II offerings. We also
         note that you appear to have an active reporting obligation pursuant
to Section 15(d) of the
         Exchange Act. Please revise this section to clarify whether you intend
to continue to
         provide reports pursuant to Section 15(d) and whether you will satisfy
your Regulation A
         reporting requirements with the filing of these reports. Consider Rule
257(b)(6) of
         Regulation A.
 Robert Mattacchione
FirstName LastNameRobert Mattacchione
Novo Integrated Sciences, Inc.
Comapany NameNovo Integrated Sciences, Inc.
April 29, 2020
April 3 2020 Page 3
Page 29,
FirstName LastName
General

7.       Section 22(a) of your amended and restated articles of incorporation
contains a forum
         selection provision that designates a state or federal court located
within the state of
         Nevada as the exclusive forum for certain types of actions, including
any "derivative"
         action. Please revise to clearly and prominently describe the
provision, including whether
         it applies to claims arising under the U.S. federal securities laws.
To the extent this
         provision applies to claims arising under the Exchange Act, please be
advised that Section
         27 of the Exchange Act creates exclusive federal jurisdiction over all
suits brought to
         enforce any duty or liability created by the Exchange Act or the rules
and regulations
         thereunder. Additionally, please revise to describe any risks or
impacts on investors and
         any uncertainty about the enforceability of this provision.
        We will consider qualifying your offering statement at your request. If
a participant in
your offering is required to clear its compensation arrangements with FINRA,
please have
FINRA advise us that it has no objections to the compensation arrangements
prior to
qualification.

        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence of
action by the staff. We also remind you that, following qualification of your
Form 1-A, Rule 257
of Regulation A requires you to file periodic and current reports, including a
Form 1-K which
will be due within 120 calendar days after the end of the fiscal year covered
by the report.

       You may contact Laura Veator, Staff Accountant, at (202) 551-3716 or
Stephen
Krikorian, Accounting Branch Chief, at (202) 551-3488 if you have questions
regarding
comments on the financial statements and related matters. Please contact
Mitchell Austin, Staff
Attorney, at (202) 551-3574 or Kathleen Krebs, Special Counsel, at (202)
551-3350 with any
other questions.



                                                              Sincerely,

                                                              Division of
Corporation Finance
                                                              Office of
Technology
cc:      Laura Anthony, Esq.