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Waters (WAT)

282 patents

Page 7 of 15
Utility
Low Binding Surfaces for Peptide Mapping
19 Aug 21
The present disclosure discusses a method of separating a sample (e.g., peptide compound) including coating a flow path of a chromatographic system; injecting the sample into the chromatographic system; flowing the sample through the chromatographic system; separating the sample; and analyzing the separated sample.
Robert Birdsall, Jacob Kellett, Nilini Ranbaduge, Ying Qing Yu, Jennifer M. Nguyen, Matthew A. Lauber
Filed: 15 Jan 21
Utility
Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides
17 Aug 21
The invention relates to poly-amide bonded hydrophilic interaction chromatography (HILIC) stationary phases and novel HILIC methods for use in the characterization of large biological molecules modified with polar groups, known to those skilled in the art as glycans.
Matthew A. Lauber, Stephan M. Koza, Pamela C. Iraneta, Kevin D. Wyndham
Filed: 2 Apr 15
Utility
Polar pesticide determination using chromatography
17 Aug 21
The present disclosure relates to the determination of pesticides, e.g., polar pesticides, in a sample using chromatography.
Dimple D. Shah, Jacob N. Fairchild, Euan Ross, Benjamin Wuyts
Filed: 7 Mar 18
Utility
Devices and methods for analyzing intact proteins, antibodies, antibody subunits, and antibody drug conjugates
17 Aug 21
The present disclosure relates devices and methods for analyzing intact antibodies, antibody subunits, antibody drug conjugate subunits, antibody drug conjugates, and intact proteins in a biological mixture.
Gregory T. Roman, James P. Murphy
Filed: 27 Feb 18
Utility
Modular Sample Preparation Devices and Methods
12 Aug 21
The present technology relates to a customizable sample preparation device (e.g., liquid sample preparation device, such as a purification, clean-up, or separation device).
Anna K. Boardman, Xiaoxiao Liu, Micah Watt, Jonathan Belanger, Matthew A. Lauber, Michael Lavallee, Wenhao Zhu
Filed: 3 Feb 21
Utility
Techniques for monitoring chromatographic fluid flows
10 Aug 21
Various embodiments are generally directed to techniques for monitoring chromatographic fluid flows, such as the flow to and/or from one or more reservoirs used in chromatographic operations, for instance.
Abhijit Tarafder, Jonathan Belanger, Moon Chul Jung, Wade P. Leveille
Filed: 12 Jun 19
Utility
Superficially Porous Materials Comprising a Substantially Nonporous Core Having Narrow Particle Size Distribution; Process for the Preparation Thereof; and Use Thereof for Chromatographic Separations
5 Aug 21
Novel chromatographic materials for chromatographic separations, columns, kits, and methods for preparation and separations with a superficially porous material comprising a substantially nonporous core and one or more layers of a porous shell material surrounding the core.
Kevin D. Wyndham, Beatrice W. Muriithi, Michael F. Morris, Nicole L. Lawrence
Filed: 2 Apr 21
Utility
Porous Inorganic/organic Hybrid Particles Having High Organic Content and Enhanced Pore Geometry for Chromatographic Separations
5 Aug 21
Novel particles and materials for chromatographic separations, processes for preparation and separations devices containing the chromatographic particles and materials are provided by the instant invention.
Kevin D. Wyndham, John E. O'Gara, Nicole Lawrence L. Lawrence
Filed: 16 Feb 21
Utility
Device and Methods for Performing Size Exclusion Chromatography
5 Aug 21
The present invention is directed to a device and a method for performing size exclusion chromatography.
Edouard S. P. Bouvier, Kevin D. Wyndham, Thomas H. Walter, Uwe D. Neue
Filed: 11 Feb 21
Utility
LC/MS Adduct Mitigation by Vapor Deposition Coated Surfaces
5 Aug 21
The present disclosure discusses a method of separating a sample (e.g., small organic acid metabolite) including coating a flow path of a chromatographic system.
Kerri M. Smith, Paul Rainville
Filed: 15 Jan 21
Utility
Continuous determination of medium stiffness and load gain for adaptive actuator control
3 Aug 21
An actuator control system, mechanical testing system, and method for adaptive control of an actuator of a mechanical testing device may include determining a stiffness of a medium that the actuator is moving through and/or load gain of the actuator, wherein the stiffness and load gain is determined by generating a waveform to actuate the actuator until a load sensor signal and/or a displacement sensor signal is received, and controllably moving the actuator through the medium according to a predefined constant velocity by calculating a current request using the stiffness of the medium, and/or adjusting the load of the actuator in accordance with a constant load ramp rate.
Kevin Alstrin
Filed: 2 Oct 18
Utility
Systems and methods for chromatographic analysis
3 Aug 21
Methods of chromatographic detection are provided that include the step of providing a chromatography instrument without an autosampler, an external device, a pressurized sample injection device and a chromatographic data system.
Aaron D. Phoebe, Sylvain G. Cormier, Charles H. Phoebe, Jr.
Filed: 24 Sep 18
Utility
Novel Sprayer Assembly for Desi Applications
29 Jul 21
A sprayer assembly for an ion source is disclosed.
Wade P. Leveille, Joseph D. Michienzi, Jeffrey Musacchio, Emrys Jones, Steven Derek Pringle, Stephen Hattan, Gregory T. Roman
Filed: 22 Jan 21
Utility
Porous carbon-heteroatom-silicon inorganic/organic materials for chromatographic separations and process for the preparation thereof
27 Jul 21
The present disclosure provides porous carbon-heteroatom-silicon inorganic/organic homogenous copolymeric hybrid materials, methods for their preparation, and uses thereof, e.g., as chromatographic separations materials.
Kevin D. Wyndham, John E. O'Gara
Filed: 16 Jan 17
Utility
High Purity Chromatrographic Materials Comprising an Ionizable Modifier
22 Jul 21
The present invention provides novel chromatographic materials, e.g., for chromatographic separations, processes for its preparation and separations devices containing the chromatographic material; separations devices, chromatographic columns and kits comprising the same; and methods for the preparation thereof.
Kevin D. Wyndham, Pamela C. Iraneta, Thomas H. Walter
Filed: 12 Mar 21
Utility
Performance and Dynamic Range for Oligonucleotide Bioanalysis Through Reduction of Non Specific Binding
22 Jul 21
The present disclosure discusses a method of separating a sample including oligonucleotides including coating a flow path of a chromatographic system; injecting the sample comprising oligonucleotides into the chromatographic system; flowing the sample through the chromatographic system; and separating the oligonucleotides.
Michael Donegan, Martin Gilar, Armand Gatien Ngounou Wetie
Filed: 15 Jan 21
Utility
Methods to Increase Sensitivity of LC/MS Analysis
22 Jul 21
The present disclosure discusses a method of separating a sample (e.g., pharmaceutical drug, genotoxic impurity, biomarker, and/or biological metabolite) including coating a metallic flow path of a chromatographic system; injecting the sample into the chromatographic system; flowing the sample through the chromatographic system; separating the sample; and analyzing the separated sample using mass spectroscopy.
Paul Rainville, Kerri Smith
Filed: 15 Jan 21
Utility
Porous Materials for Solid Phase Extraction and Chromatography and Processes for Preparation and Use Thereof
22 Jul 21
The present invention provides porous materials for use in solid phase extractions and chromatography.
Mingcheng Xu, Darryl W. Brousmiche, Kevin Wyndham
Filed: 2 Apr 21
Utility
Use of Vapor Deposition Coated Flow Paths for Improved Chromatography of Metal Interacting Analytes
22 Jul 21
A chromatographic device including a coated metallic frit is disclosed.
Stephen J. Shiner, Cheryl Boissel, Matthew A. Lauber, Kevin Wyndham, Michael O. Fogwill
Filed: 17 Mar 21
Utility
Fixture Identification In Test Systems
22 Jul 21
Described are systems and methods for fixture identification in test systems.
David L. Dingmann
Filed: 15 Jan 21
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