426 patents
Page 9 of 22
Utility
Chromatography Column Positioning Assemblies
28 Apr 22
The exemplary embodiments provide chromatography column positioning assemblies that can ensure that the distance between face seals or other sealing surfaces/mechanisms at the respective ends of a liquid chromatography column is a desired distance (i.e., the length of the liquid chromatography column).
Wade P. Leveille, Joseph D. Michienzi, Jeffrey Musacchio, Michael O. Fogwill
Filed: 28 Oct 21
Utility
Device Including a Hydrophilic, Non-ionic Coating for Size Exclusion Chromatography
21 Apr 22
The present disclosure is directed to a coating process for chromatographic surfaces.
Mathew H. DeLano, Matthew Lauber, Andrew Wyatt Schmudlach, Daniel P. Walsh, Yeliz Tunc Sarisozen, Jonathan Belanger, Darryl W. Brousmiche, Andrew Bates-Harrison, Nicole L. Lawrence
Filed: 15 Oct 21
Utility
Workflows for Preparing and Analyzing Clinical Samples
21 Apr 22
The present disclosure relates to methods and workflows for processing and analyzing clinical samples (e.g., nasal swabs, throat swabs, plasma samples, urine, etc.) In general, the methods and workflows involve the detection of an infectious state and are improved over contemporary methods due to increased throughput with improved resolution of positive results.
Thomas S. McDonald, Kevin Wyndham, Johannes Vissers, Edouard S. P. Bouvier
Filed: 13 Oct 21
Utility
Methods for determination of polar pesticides by chromatography
19 Apr 22
The disclosure relates to a reversed-phase chromatography method for the determination of at least one of glyphosate or AMPA in a sample.
Danilo Augusto Alves Pereira, Mirela Talarico Afonso De Moura, Marcella Fernanda Alves Reis
Filed: 17 Jul 19
Utility
Hybrid inorganic/organic materials having novel surface modification; process for the preparation of inorganic/organic hybrid materials; and use of said particles for chromatographic separations
5 Apr 22
The present invention provides novel chromatographic materials, e.g., for chromatographic separations, processes for their preparation and separations devices containing the chromatographic materials.
Kevin D. Wyndham
Filed: 1 Jun 10
Utility
High resolution and semi-preparative recycling chromatography system for isolation and preparation of unknown trace impurities in pharmaceutical products
29 Mar 22
The disclosure relates to a recycling chromatography method that includes injecting a sample into a mobile phase flow stream of a chromatography system to create a combined flow stream.
Fabrice Gritti, Sylvain Cormier
Filed: 30 May 19
Utility
Chromatographic Hardware Improvements for Separation of Reactive Molecules
24 Mar 22
The present disclosure relates to a method of reducing degradation of sample components in a liquid chromatography system.
Mathew DeLano, Matthew A. Lauber, Kevin Wyndham, Jennifer M. Nguyen
Filed: 24 Sep 21
Utility
Continuous Flow Mixer
24 Mar 22
A continuous flow mixer for use in a chromatography system includes a first channel structure located between a mixer inlet and a mixer outlet.
Sean Eric Anderson, Peter MacKinnon
Filed: 22 Sep 21
Utility
Compounds for Use In System Suitability Testing of Inert LC Systems and Columns
24 Mar 22
The present disclosure is directed to a kit for evaluating system inertness.
Amit Patel, Moon Chul Jung, Susan Rzewuski, Matthew A. Lauber, Thomas H. Walter, Kevin Wyndham, Mathew DeLano, Jennifer Simeone
Filed: 10 Sep 21
Utility
Encapsulated pre-analytic workflows for flow-through devices, liquid chromatography and mass spectrometric analysis
22 Mar 22
This invention relates to encapsulated workflow reagents comprising an encapsulating material and a workflow reagent encapsulated within the encapsulating material for sample and workflow preparation prior to chromatographic, spectroscopic or other analytical systems, use thereof, and devices comprising the same.
Kevin Daniel Wyndham, Darryl W. Brousmiche
Filed: 28 Jul 17
Utility
Mechanisms and methods for liquid sample introduction into a chromatography system
22 Mar 22
The disclosure relates to a system for liquid sample introduction into a chromatography system.
Jason Hill, Abhijit Tarafder, Michael O. Fogwill, Thomas McDonald, Sylvain Cormier
Filed: 8 Nov 19
Utility
Techniques for System Suitability Testing of Inert Liquid Chromatography Systems and Columns
17 Mar 22
The present disclosure is directed to methods of characterizing a system containing a chromatographic column.
Amit Patel, Moon Chul Jung, Susan Rzewuski, Thomas H. Walter, Matthew A. Lauber, Kevin Wyndham, Mathew DeLano, Jennifer Simeone
Filed: 10 Sep 21
Utility
Methods for the Evaluation of System Inertness
17 Mar 22
The present disclosure is directed to methods for evaluating system inertness, such as the inertness of a LC or other fluidic system.
Amit Patel, Moon Chul Jung, Susan Rzewuski, Thomas H. Walter, Matthew A. Lauber, Kevin Wyndham, Mathew DeLano, Jennifer Simeone
Filed: 10 Sep 21
Utility
Silica-based Particle with Hydroxy-terminated Peg Bonding and Methoxy-terminated Peg Surface Modification
17 Mar 22
The present disclosure is directed to stationary phase materials for performing size exclusion chromatography.
Nicole L. Lawrence, Yeliz Tunc Sarisozen, Darryl W. Brousmiche, Matthew A. Lauber
Filed: 16 Sep 21
Utility
Sorbent Used to Improve Chromatographic Separations In Size Exclusion Chromatography Via Reduced Secondary Interactions
17 Mar 22
The present disclosure is directed to stationary phase materials (e.g., porous inorganic-organic hybrid particles) for performing size exclusion chromatography.
Yeliz Tunc Sarisozen, Nicole L. Lawrence, Darryl W. Brousmiche, Andrew Wyatt Schmudlach, Matthew A. Lauber
Filed: 16 Sep 21
Utility
Size Exclusion Chromatography Utilizing Low Concentration Amino Acids In Size Exclusion Chromatography Mobile Phase
17 Mar 22
The present disclosure is directed to methods for performing size exclusion chromatography.
Andrew Wyatt Schmudlach, Susan Rzewuski, Matthew A. Lauber, Yeliz Tunc Sarisozen, Nicole L. Lawrence, Darryl W. Brousmiche
Filed: 16 Sep 21
Utility
Techniques for thermally insulating a liquid chromatographic column
15 Mar 22
An apparatus for performing liquid chromatography includes a chromatography column, and an insulating member surrounding the chromatography column wherein the insulating member is formed from a vacuum chamber surrounding the chromatography column.
Edouard S. P. Bouvier, Pamela C. Iraneta, Joseph A. Luongo, Joseph A. Jarrell
Filed: 13 Sep 19
Utility
Reconfigurable fluidic manifold for a liquid chromatography system
15 Mar 22
Described is a fluidic manifold that includes a block formed of multiple layers each bonded to at least one adjacent layer at a layer interface.
Jeffrey Musacchio, Keith Fadgen, Joseph D. Michienzi, Stanislaw Koziol
Filed: 20 Aug 19
Utility
Multidimensional Chromatography Method for Analysis of Antibody-drug Conjugates
10 Mar 22
The present disclosure relates to a sensitive, multidimensional chromatography method for extraction, detection, and quantification of non-conjugated cytotoxic agents and associated linker molecules used in cysteine based antibody-drug-conjugate production.
Robert Birdsall
Filed: 24 Sep 21
Utility
Thermogravimetric analysis components
8 Mar 22
Described is a convection reducer.
Cornelia Will
Filed: 9 Dec 19