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Waters (WAT)

Utility
Devices and Methods for Temperature Correction for Lateral Flow Testing
16 Jun 22
Temperature effects on results of a lateral flow assay can be compensated for by measuring an environmental temperature at a testing time and a testing location, performing a lateral flow assay at the testing time and testing location to obtain an original concentration value of a target substance, and generating a modified concentration value of the target substance.
Lingyun Chen, John Davenport
Filed: 7 Dec 21
Utility
Evaporator for a Thermogravimetric Analyzer
9 Jun 22
Described is a thermogravimetric analyzer system.
Cornelia Will, Joseph D. Michienzi, Sornanathan Meyyappan, Jürgen Helmut Neumann
Filed: 30 Nov 21
Utility
Systems and Methods for Measuring a Concentration of an Analyte
2 Jun 22
The present disclosure relates to systems and methods for determination of analyte concentrations in solution using materials that are pre-dispensed and dried on conjugate pads or other solid substrates.
Lingyun Chen, Jianmin Liu
Filed: 16 Feb 22
Utility
Methods and Compositions Useful for Nucleic Acid Analysis
12 May 22
The present disclosure relates to compositions that comprise a fluorescent and/or MS-active nucleic acid probe that comprises (a) a nucleic-acid-based moiety and (b) a fluorescent moiety comprising a fluorophore, an MS-active moiety, or both a fluorescent moiety and an MS-active moiety, linked to the nucleic-acid-based moiety, among other aspects.
Armand Gatien Ngounou Wetie, Mark D. Wrona, Darryl W. Brousmiche
Filed: 4 Nov 21
Utility
Conical Columns and Low Dispersion Frits
28 Apr 22
Disclosed herein are chromatography columns with conical or reducing inside dimensions and improved fits for use therewith, along with methods for making the columns and the frits.
Fabrice Gritti, Jonathan Belanger, Daniel Marc Lemire, JR.
Filed: 19 Oct 21
Utility
Ported End Fitting for a Liquid Chromatography Column with an Integrated Valve/tee Having Additional Input And/or Output
28 Apr 22
Exemplary embodiments integrate a tee or valve into an outlet end fitting of a liquid chromatography column.
Wade P. Leveille, Sylvain G. Cormier, Michael O. Fogwill, Joseph D. Michienzi, Jeffrey Musacchio, Joseph D. Antocci
Filed: 28 Oct 21
Utility
Chromatography Column Positioning Assemblies
28 Apr 22
The exemplary embodiments provide chromatography column positioning assemblies that can ensure that the distance between face seals or other sealing surfaces/mechanisms at the respective ends of a liquid chromatography column is a desired distance (i.e., the length of the liquid chromatography column).
Wade P. Leveille, Joseph D. Michienzi, Jeffrey Musacchio, Michael O. Fogwill
Filed: 28 Oct 21
Utility
Device Including a Hydrophilic, Non-ionic Coating for Size Exclusion Chromatography
21 Apr 22
The present disclosure is directed to a coating process for chromatographic surfaces.
Mathew H. DeLano, Matthew Lauber, Andrew Wyatt Schmudlach, Daniel P. Walsh, Yeliz Tunc Sarisozen, Jonathan Belanger, Darryl W. Brousmiche, Andrew Bates-Harrison, Nicole L. Lawrence
Filed: 15 Oct 21
Utility
Workflows for Preparing and Analyzing Clinical Samples
21 Apr 22
The present disclosure relates to methods and workflows for processing and analyzing clinical samples (e.g., nasal swabs, throat swabs, plasma samples, urine, etc.) In general, the methods and workflows involve the detection of an infectious state and are improved over contemporary methods due to increased throughput with improved resolution of positive results.
Thomas S. McDonald, Kevin Wyndham, Johannes Vissers, Edouard S. P. Bouvier
Filed: 13 Oct 21
Utility
Chromatographic Hardware Improvements for Separation of Reactive Molecules
24 Mar 22
The present disclosure relates to a method of reducing degradation of sample components in a liquid chromatography system.
Mathew DeLano, Matthew A. Lauber, Kevin Wyndham, Jennifer M. Nguyen
Filed: 24 Sep 21
Utility
Continuous Flow Mixer
24 Mar 22
A continuous flow mixer for use in a chromatography system includes a first channel structure located between a mixer inlet and a mixer outlet.
Sean Eric Anderson, Peter MacKinnon
Filed: 22 Sep 21
Utility
Compounds for Use In System Suitability Testing of Inert LC Systems and Columns
24 Mar 22
The present disclosure is directed to a kit for evaluating system inertness.
Amit Patel, Moon Chul Jung, Susan Rzewuski, Matthew A. Lauber, Thomas H. Walter, Kevin Wyndham, Mathew DeLano, Jennifer Simeone
Filed: 10 Sep 21
Utility
Silica-based Particle with Hydroxy-terminated Peg Bonding and Methoxy-terminated Peg Surface Modification
17 Mar 22
The present disclosure is directed to stationary phase materials for performing size exclusion chromatography.
Nicole L. Lawrence, Yeliz Tunc Sarisozen, Darryl W. Brousmiche, Matthew A. Lauber
Filed: 16 Sep 21
Utility
Sorbent Used to Improve Chromatographic Separations In Size Exclusion Chromatography Via Reduced Secondary Interactions
17 Mar 22
The present disclosure is directed to stationary phase materials (e.g., porous inorganic-organic hybrid particles) for performing size exclusion chromatography.
Yeliz Tunc Sarisozen, Nicole L. Lawrence, Darryl W. Brousmiche, Andrew Wyatt Schmudlach, Matthew A. Lauber
Filed: 16 Sep 21
Utility
Size Exclusion Chromatography Utilizing Low Concentration Amino Acids In Size Exclusion Chromatography Mobile Phase
17 Mar 22
The present disclosure is directed to methods for performing size exclusion chromatography.
Andrew Wyatt Schmudlach, Susan Rzewuski, Matthew A. Lauber, Yeliz Tunc Sarisozen, Nicole L. Lawrence, Darryl W. Brousmiche
Filed: 16 Sep 21
Utility
Techniques for System Suitability Testing of Inert Liquid Chromatography Systems and Columns
17 Mar 22
The present disclosure is directed to methods of characterizing a system containing a chromatographic column.
Amit Patel, Moon Chul Jung, Susan Rzewuski, Thomas H. Walter, Matthew A. Lauber, Kevin Wyndham, Mathew DeLano, Jennifer Simeone
Filed: 10 Sep 21
Utility
Methods for the Evaluation of System Inertness
17 Mar 22
The present disclosure is directed to methods for evaluating system inertness, such as the inertness of a LC or other fluidic system.
Amit Patel, Moon Chul Jung, Susan Rzewuski, Thomas H. Walter, Matthew A. Lauber, Kevin Wyndham, Mathew DeLano, Jennifer Simeone
Filed: 10 Sep 21
Utility
Multidimensional Chromatography Method for Analysis of Antibody-drug Conjugates
10 Mar 22
The present disclosure relates to a sensitive, multidimensional chromatography method for extraction, detection, and quantification of non-conjugated cytotoxic agents and associated linker molecules used in cysteine based antibody-drug-conjugate production.
Robert Birdsall
Filed: 24 Sep 21
Utility
Multiple Sample Differential Scanning Calorimeter
3 Mar 22
A heat flow rate measurement method for use with a differential scanning calorimeter sensor is provided.
Robert L. Danley
Filed: 10 Nov 21
Utility
Hybrid Calorimeter Cell
3 Mar 22
A calorimeter and method is also provided, including a sample cell, a reference cell, a thermostat in thermal communication with the sample cell and the reference cell, a first conductive wire, the first conductive wire having a first end connected to the thermostat and a second end connected to the sample cell, and a second conductive wire, the second conductive wire having a first end connected to the thermostat and a second end connected to the reference cell.
Donald J. Russell, Anthony E. Arnerich, David Serrell
Filed: 9 Nov 21
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