230 patents
Page 4 of 12
Utility
Encapsulated Pre-analytic Workflows for Flow-through Devices, Liquid Chromatography and Mass Spectrometric Analysis
11 Aug 22
This invention relates to encapsulated reagents for sample and workflow preparation prior to chromatographic, spectroscopic or other analytical systems, use thereof, and devices comprising the same.
Kevin Daniel Wyndham, Darryl W. Brousmiche
Filed: 17 Feb 22
Utility
Thermally-controlled Low Pressure Mixing System for Liquid Chromatography
4 Aug 22
Described is a solvent manager for a liquid chromatography system.
Timothy M. Raymond, Peter MacKinnon, Michael R. Jackson
Filed: 31 Jan 22
Utility
Rotary Valve Having Bypass State
28 Jul 22
Described is a rotary valve that includes a stator, a rotor and a plurality of sample channels.
Sylvain Gilles Cormier, Charles T. Murphy, Joseph D. Michienzi
Filed: 25 Jan 22
Utility
Variable Fluidic Restrictor Having Selective Restriction
21 Jul 22
A variable fluidic restrictor of a liquid chromatography system including a stator body, the stator body include a plurality of fluidic channels located within the stator body, wherein each fluidic channel of the plurality of fluidic channels includes a restrictor element, wherein a flow of a fluid through the variable fluidic restrictor is selectively restricted based on a position of an external element coupled to the stator body is provided.
Zongren Shang, Stanislaw Koziol, Joseph D. Michienzi, Michael Eggertson, Keith Fadgen
Filed: 8 Apr 22
Utility
Autosampler Seal Pack for Reducing a Carryover Percentage
21 Jul 22
A seal pack of a sample manager of a liquid chromatography system having a plurality of wash flow pathways fluidically connected to a central pathway that accommodates a sample needle, wherein a first wash flow pathway is vertically offset from a second wash flow pathway, such that a wash solution flows axially along an exterior surface of the sample needle in a vertical direction to wash the sample needle when flowing from the first wash flow pathway to the vertically offset second wash flow pathway, is provided.
Joshua A. Burnett, Marc E. Lemelin, Sylvain Gilles Cormier
Filed: 8 Apr 22
Utility
Active Check Valve Having a Moving Magnet Actuator
14 Jul 22
Described is an active check valve that uses electro-magnetic actuation for operation.
Sean Eric Anderson, Wade P. Leveille
Filed: 6 Jan 22
Utility
Change Detection In Material Testing
14 Jul 22
Disclosed is a material testing system that includes a fixture, a frame, a load sensor, a displacement sensor and a computer system coupled to the material testing system.
David L. Dingmann
Filed: 21 Dec 21
Utility
Hybrid Inorganic/organic Materials Having Novel Surface Modification; Process for the Preparation of Inorganic/organic Hybrid Materials; and Use of Said Particles for Chromatographic Separations
30 Jun 22
The present invention provides novel chromatographic materials, e.g., for chromatographic separations, processes for their preparation and separations devices containing the chromatographic materials.
Kevin Wyndham
Filed: 7 Mar 22
Utility
Vial Cap for a Liquid Chromatography Sample Vial
30 Jun 22
A vial cap for a sample vial includes a cylindrical cap body defining a first circular opening at a first end.
Moon Chul Jung
Filed: 1 Jun 21
Utility
Method for Determining B Vitamins and Their Vitamers
30 Jun 22
The present disclosure discusses a method of separating a sample (e.g., B vitamins and their vitamers) including coating a flow path of a chromatographic system; injecting the sample into the chromatographic system; flowing the sample through the chromatographic system; separating the sample; and analyzing the separated sample.
Jinchuan Yang, Paul Rainville
Filed: 29 Dec 21
Utility
Devices and Methods for Temperature Correction for Lateral Flow Testing
16 Jun 22
Temperature effects on results of a lateral flow assay can be compensated for by measuring an environmental temperature at a testing time and a testing location, performing a lateral flow assay at the testing time and testing location to obtain an original concentration value of a target substance, and generating a modified concentration value of the target substance.
Lingyun Chen, John Davenport
Filed: 7 Dec 21
Utility
Evaporator for a Thermogravimetric Analyzer
9 Jun 22
Described is a thermogravimetric analyzer system.
Cornelia Will, Joseph D. Michienzi, Sornanathan Meyyappan, Jürgen Helmut Neumann
Filed: 30 Nov 21
Utility
Systems and Methods for Measuring a Concentration of an Analyte
2 Jun 22
The present disclosure relates to systems and methods for determination of analyte concentrations in solution using materials that are pre-dispensed and dried on conjugate pads or other solid substrates.
Lingyun Chen, Jianmin Liu
Filed: 16 Feb 22
Utility
Methods and Compositions Useful for Nucleic Acid Analysis
12 May 22
The present disclosure relates to compositions that comprise a fluorescent and/or MS-active nucleic acid probe that comprises (a) a nucleic-acid-based moiety and (b) a fluorescent moiety comprising a fluorophore, an MS-active moiety, or both a fluorescent moiety and an MS-active moiety, linked to the nucleic-acid-based moiety, among other aspects.
Armand Gatien Ngounou Wetie, Mark D. Wrona, Darryl W. Brousmiche
Filed: 4 Nov 21
Utility
Conical Columns and Low Dispersion Frits
28 Apr 22
Disclosed herein are chromatography columns with conical or reducing inside dimensions and improved fits for use therewith, along with methods for making the columns and the frits.
Fabrice Gritti, Jonathan Belanger, Daniel Marc Lemire, JR.
Filed: 19 Oct 21
Utility
Ported End Fitting for a Liquid Chromatography Column with an Integrated Valve/tee Having Additional Input And/or Output
28 Apr 22
Exemplary embodiments integrate a tee or valve into an outlet end fitting of a liquid chromatography column.
Wade P. Leveille, Sylvain G. Cormier, Michael O. Fogwill, Joseph D. Michienzi, Jeffrey Musacchio, Joseph D. Antocci
Filed: 28 Oct 21
Utility
Chromatography Column Positioning Assemblies
28 Apr 22
The exemplary embodiments provide chromatography column positioning assemblies that can ensure that the distance between face seals or other sealing surfaces/mechanisms at the respective ends of a liquid chromatography column is a desired distance (i.e., the length of the liquid chromatography column).
Wade P. Leveille, Joseph D. Michienzi, Jeffrey Musacchio, Michael O. Fogwill
Filed: 28 Oct 21
Utility
Device Including a Hydrophilic, Non-ionic Coating for Size Exclusion Chromatography
21 Apr 22
The present disclosure is directed to a coating process for chromatographic surfaces.
Mathew H. DeLano, Matthew Lauber, Andrew Wyatt Schmudlach, Daniel P. Walsh, Yeliz Tunc Sarisozen, Jonathan Belanger, Darryl W. Brousmiche, Andrew Bates-Harrison, Nicole L. Lawrence
Filed: 15 Oct 21
Utility
Workflows for Preparing and Analyzing Clinical Samples
21 Apr 22
The present disclosure relates to methods and workflows for processing and analyzing clinical samples (e.g., nasal swabs, throat swabs, plasma samples, urine, etc.) In general, the methods and workflows involve the detection of an infectious state and are improved over contemporary methods due to increased throughput with improved resolution of positive results.
Thomas S. McDonald, Kevin Wyndham, Johannes Vissers, Edouard S. P. Bouvier
Filed: 13 Oct 21
Utility
Chromatographic Hardware Improvements for Separation of Reactive Molecules
24 Mar 22
The present disclosure relates to a method of reducing degradation of sample components in a liquid chromatography system.
Mathew DeLano, Matthew A. Lauber, Kevin Wyndham, Jennifer M. Nguyen
Filed: 24 Sep 21