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Waters (WAT)

Utility
Interface module for two-dimensional liquid chromatography
14 Jun 22
Described are an interface module for two-dimensional chromatography and a method of performing a chromatographic separation that may use the interface module.
Sylvain Gilles Cormier, Charles H. Phoebe, Jr.
Filed: 30 Aug 19
Utility
Techniques for accelerating thermal equilibrium in a chromatographic column
7 Jun 22
Techniques are described for accelerating thermal equilibrium in a chromatographic column.
Edouard S. P. Bouvier, Joseph Kareh
Filed: 8 Oct 19
Utility
Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
7 Jun 22
Darryl W. Brousmiche, Matthew A. Lauber
Filed: 25 Jan 16
Utility
Methods of enhancing MS detection of tagged glycans
7 Jun 22
Methods for derivatization of biomolecules including glycans or other biopolymers with one or more fluorescent, MS active compounds by reductive amination or rapid tagging in order to produce derivatized glycan having a pKa>7 and between about 200 Å2 and about 1000 Å2 of nonpolar surface area are described.
Darryl W. Brousmiche, Matthew A. Lauber
Filed: 19 Jun 17
Utility
Mechanisms and methods for liquid sample introduction into a chromatography system
24 May 22
The disclosure relates to a system for liquid sample introduction into a chromatography system.
Jason Hill, Abhijit Tarafder, Joshua Burnett, Michael O. Fogwill
Filed: 8 Nov 19
Utility
System and method for controlling fluid flow within a liquid chromatography system
24 May 22
The present disclosure relates to methodologies, systems, and apparatus for controlling fluid flow within a chromatography system.
Michael O. Fogwill, Theodore A. Dourdeville
Filed: 29 May 19
Utility
Multi-dimensional chromatographic system for analyzing multiple sample components
17 May 22
A chromatography system includes a first chromatography column for receiving and separating a flow stream, a plurality of traps configured to trap a plurality of distinct flow segments exiting the first chromatography column during separation of the flow stream, and a second chromatography column operatively associated with the plurality of traps for receiving and separating the distinct flow segments.
Amanda B. Dlugasch, Thomas E. Wheat, Daniel Root, Jean-Michel Plankeele, Isabelle Francois, Edward R. Aig
Filed: 16 Sep 20
Utility
Chemical class compositions from collision cross-section fragment ions
17 May 22
The present disclosure generally relates to methods for determining chemical class compositions present in a sample using collision cross-section fragment ion values.
Giuseppe Astarita, Scott Geromanos
Filed: 30 Jun 17
Utility
Variable fluidic restrictor having selective restriction
10 May 22
A variable fluidic restrictor of a liquid chromatography system including a stator body, the stator body include a plurality of fluidic channels located within the stator body, wherein each fluidic channel of the plurality of fluidic channels includes a restrictor element, wherein a flow of a fluid through the variable fluidic restrictor is selectively restricted based on a position of an external element coupled to the stator body is provided.
Zongren Shang, Stanislaw Koziol, Joseph D. Michienzi, Michael Eggertson, Keith Fadgen
Filed: 20 Aug 19
Utility
Autosampler seal pack for reducing a carryover percentage
10 May 22
A seal pack of a sample manager of a liquid chromatography system having a plurality of wash flow pathways fluidically connected to a central pathway that accommodates a sample needle, wherein a first wash flow pathway is vertically offset from a second wash flow pathway, such that a wash solution flows axially along an exterior surface of the sample needle in a vertical direction to wash the sample needle when flowing from the first wash flow pathway to the vertically offset second wash flow pathway, is provided.
Joshua A. Burnett, Marc E. Lemelin, Sylvain Gilles Cormier
Filed: 28 Mar 19
Utility
Methods for determination of polar pesticides by chromatography
19 Apr 22
The disclosure relates to a reversed-phase chromatography method for the determination of at least one of glyphosate or AMPA in a sample.
Danilo Augusto Alves Pereira, Mirela Talarico Afonso De Moura, Marcella Fernanda Alves Reis
Filed: 17 Jul 19
Utility
Hybrid inorganic/organic materials having novel surface modification; process for the preparation of inorganic/organic hybrid materials; and use of said particles for chromatographic separations
5 Apr 22
The present invention provides novel chromatographic materials, e.g., for chromatographic separations, processes for their preparation and separations devices containing the chromatographic materials.
Kevin D. Wyndham
Filed: 1 Jun 10
Utility
High resolution and semi-preparative recycling chromatography system for isolation and preparation of unknown trace impurities in pharmaceutical products
29 Mar 22
The disclosure relates to a recycling chromatography method that includes injecting a sample into a mobile phase flow stream of a chromatography system to create a combined flow stream.
Fabrice Gritti, Sylvain Cormier
Filed: 30 May 19
Utility
Encapsulated pre-analytic workflows for flow-through devices, liquid chromatography and mass spectrometric analysis
22 Mar 22
This invention relates to encapsulated workflow reagents comprising an encapsulating material and a workflow reagent encapsulated within the encapsulating material for sample and workflow preparation prior to chromatographic, spectroscopic or other analytical systems, use thereof, and devices comprising the same.
Kevin Daniel Wyndham, Darryl W. Brousmiche
Filed: 28 Jul 17
Utility
Mechanisms and methods for liquid sample introduction into a chromatography system
22 Mar 22
The disclosure relates to a system for liquid sample introduction into a chromatography system.
Jason Hill, Abhijit Tarafder, Michael O. Fogwill, Thomas McDonald, Sylvain Cormier
Filed: 8 Nov 19
Utility
Techniques for thermally insulating a liquid chromatographic column
15 Mar 22
An apparatus for performing liquid chromatography includes a chromatography column, and an insulating member surrounding the chromatography column wherein the insulating member is formed from a vacuum chamber surrounding the chromatography column.
Edouard S. P. Bouvier, Pamela C. Iraneta, Joseph A. Luongo, Joseph A. Jarrell
Filed: 13 Sep 19
Utility
Reconfigurable fluidic manifold for a liquid chromatography system
15 Mar 22
Described is a fluidic manifold that includes a block formed of multiple layers each bonded to at least one adjacent layer at a layer interface.
Jeffrey Musacchio, Keith Fadgen, Joseph D. Michienzi, Stanislaw Koziol
Filed: 20 Aug 19
Utility
Thermogravimetric analysis components
8 Mar 22
Described is a convection reducer.
Cornelia Will
Filed: 9 Dec 19
Utility
Systems and methods for refractive index detection
8 Mar 22
The invention provides differential refractive index detectors and methods for the use of differential refractive index detectors.
Anthony C. Jeannotte, Mark Basile, Senthil Bala, Colin Fredette
Filed: 13 Apr 18
Utility
Solvent reservoir filters, systems and methods
8 Feb 22
A solvent reservoir filter for a liquid chromatograph system includes a first screen extending in a first plane, the first screen configured to filter solvent received through the first screen, a second screen extending in a second plane that is parallel to the first plane, the second screen configured to filter solvent received through the second screen, a main body extending between and connecting the first screen and the second screen, and a fluid outlet configured to expel solvent filtered by the first and second screens from the solvent reservoir filter.
Mark W. Moeller, William B. Clark
Filed: 24 Jun 19
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