26 patents
Utility
Methods and Compositions for Nucleic Acid Analysis
2 Nov 23
Methods and reagent for determining the presence and/or for quantifying the amount of a target nucleic acid sequences in a sample are provided.
Douglas WHITMAN
Filed: 7 Dec 22
Utility
Digital Amplification Assay Analysis Method
2 Mar 23
Provided herein are methods and systems for detecting the presence or absence of multiple target nucleic acids in partitions of a digital amplification assay.
Jenni BERNIER, Doug WHITMAN
Filed: 17 Aug 22
Utility
Apparatus and Methods for Thermal Cycling of Sample
9 Feb 23
This disclosure relates to apparatus and methods for thermally cycling a sample.
William S. WANG, Steve KRUEGER, Douglas WHITMAN, Blaine OLDHAM, Tabitha VANDERSTOEP
Filed: 14 Sep 22
Utility
Method for Extraction of Cell-free Dna
22 Dec 22
Provided herein are compositions and methods for extracting cell-free DNA (cfDNA) from a biological sample without the need for pretreatment with proteases prior to binding of the cfDNA to a solid substrate and without a heated elution step.
Steven KRUEGER
Filed: 13 Jun 22
Utility
Methods and Compositions for Discrete Melt Analysis
17 Nov 22
Methods and reagent for determining the presence and/or for quantifying the amount of a target nucleic acid sequences in a sample are provided.
Douglas WHITMAN, Jennifer BERNIER, William WANG
Filed: 22 Jun 22
Utility
Methods and Probes for Performing PCR with Melt Analysis for Increased Multiplexing
8 Sep 22
Methods and compositions for the detection and quantification of nucleic acids are provided.
Doug WHITMAN
Filed: 25 May 22
Utility
Chimeric Primers with Hairpin Conformations and Methods of Using Same
11 Aug 22
Methods and compositions for nucleic acid amplification, detection, and genotyping techniques are disclosed.
Douglas F. WHITMAN, Hongwei ZHANG
Filed: 31 Mar 22
Utility
User Interface for a Fluorescence Assay
13 Jan 22
A fluorescence assay device performs a fluorescence assay of one or more samples including fluorescent materials, causing a plurality of sets of datapoint to be stored relating to received fluorescence emitted by the fluorescent materials.
Alpar Erdei, Joshua Lelan Callaway, Terrence Lee Hodge
Filed: 7 Jul 21
Utility
Real-time Multiplexed Hydrolysis Probe Assay Using Spectrally Identifiable Microspheres
7 Oct 21
Methods and compositions for the detection and quantification of nucleic acids are provided.
Doug WHITMAN, Brian SCHRADER
Filed: 18 Jun 21
Utility
Probes for Improved Melt Discrimination and Multiplexing In Nucleic Acid Assays
24 Jun 21
Methods and compositions for the detection and quantification of nucleic acids are provided.
Scott C. JOHNSON, Nicolas ARAB, Doug WHITMAN
Filed: 9 Mar 21
Utility
Double Trench Well for Assay Procedures
17 Jun 21
Apparatuses, systems and methods for using assay preparation plates comprising wells with two trenches are presented.
Colin BOZARTH, Ross JOHNSON, Adam SCHILFFARTH
Filed: 20 Jan 21
Utility
Using Machine Learning Algorithms to Prepare Training Datasets
18 Mar 21
A computer system is configured to receive a dataset of image-derived features for a plurality of images, reduce the dimensionality of this dataset, identify clusters within the dimensionally-reduced dataset, and generate a visual representation of the datapoint of the dimensionally-reduced dataset as icons grouped by cluster.
Bryan Richard Davidson, Vidya Venkatachalam, Artiom Zayats, Michael C. Riedel
Filed: 9 Sep 20
Utility
Rapid Cellular Lysis by Reduction/oxidation Reaction
25 Feb 21
Provided herein are methods for the rapid preparation of amplifiable nucleic acids from biological samples, which can be applied to various applications, such as, for example, point-of-care diagnostics, service laboratory diagnostics, and molecular biology applications.
Edward A. SEKINGER, Megan MARTINEZ, Mahima PANCHOLI, Kurt HOFFACKER
Filed: 17 Aug 20
Utility
Method To Combine Brightfield And Fluorescent Channels For Cell Image Segmentation And Morphological Analysis Using Images Obtained From Imaging Flow Cytometer (IFC)
4 Feb 21
A classifier engine provides cell morphology identification and cell classification in computer-automated systems, methods and diagnostic tools.
Alan LI, Shobana VAIDYANATHAN
Filed: 21 Oct 20
Utility
Detailed Assay Protocol Specification
6 Jan 21
Techniques are disclosed relating to assay configuration.
David R. Torgerson, Matthew S. Fisher
Filed: 9 Jun 19
Utility
Probes for Improved Melt Discrimination and Multiplexing In Nucleic Acid Assays
18 Nov 20
Methods and compositions for the detection and quantification of nucleic acids are provided.
Scott C. JOHNSON, Nicolas ARAB, Doug WHITMAN
Filed: 2 Aug 20
Utility
Apparatus and Methods for Thermal Cycling of Sample
4 Nov 20
This disclosure relates to apparatus and methods for thermally cycling a sample.
William S. WANG, Steve KRUEGER, Douglas WHITMAN, Blaine OLDHAM, Tabitha VANDERSTOEP
Filed: 27 Apr 20
Utility
Fluid Retention Plates and Analysis Cartridges
26 Aug 20
Fluid storage containers and analysis cartridges for use in assay processes are presented.
Ross JOHNSON, Chuck COLLINS
Filed: 13 May 20
Utility
Cleavable Hairpin Primers
19 Aug 20
Nucleic acid constructs and methods that provide superior prevention of primer-dimers and other artifacts of false priming events are disclosed.
Martin KOCHANCZYK, Doug WHITMAN
Filed: 7 May 20
Utility
Apparatus and Methods for Multi-step Channel Emulsification
19 Aug 20
Methods and devices for forming droplets are provided.
Nicolas ARAB, Arnold ESTRADA, Daniel FINE, Ross JOHNSON
Filed: 26 Apr 20