29 patents
Utility
Treatment of intrahepatic cholestatic diseases
7 Mar 23
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 3 Apr 21
Utility
Treatment of intrahepatic cholestatic diseases
9 Aug 22
Treatment of intrahepatic cholestatic diseases by therapy with MBX-8025 or an MBX-8025 salt.
Pol Boudes, Charles A. McWherter
Filed: 3 Oct 20
Utility
Treatment of cholangiopathies
4 Aug 22
Seladelpar and its salts are useful in the treatment of cholangiopathies in subjects who are intolerant of, or have an inadequate response to, obeticholic acid and/or fibrates.
Yun-Jung Choi, Charles A. McWherter, Alexandra S. Steinberg, Ke Yang
Filed: 29 Jan 22
Utility
Treatment of intrahepatic cholestatic diseases
18 Jan 22
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 18 Sep 20
Utility
Treatment of NAFLD and NASH
23 Nov 21
Treatment of NAFLD and NASH by therapy with MBX-8025 or an MBX-8025 salt.
Brian Roberts, Xueyan Wang, Yun-Jung Choi, David Karpf, Robert Martin, Charles McWherter
Filed: 19 Jun 20
Utility
CB-0406 tromethamine salt
18 Nov 21
CB-0406 tromethamine salt, especially in crystalline form and as an ansolvate, methods of preparing it, compositions containing it, and its pharmaceutical uses.
Stephan X.M. Boerrigter, Charles A. McWherter, Robert L. Martin, Jennifer L. Nelson, Jiangao Song
Filed: 12 May 21
Utility
CB-0406 choline salt
18 Nov 21
CB-0406 choline salt, especially in crystalline form and as an ansolvate, methods of preparing it, compositions containing it, and its pharmaceutical uses.
Stephan X.M. Boerrigter, Charles A. McWherter, Robert L. Martin, Jennifer L. Nelson, Jiangao Song
Filed: 12 May 21
Utility
Treatment of cholestatic pruritus
16 Sep 21
Treatment of cholestatic pruritus by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter, Alexandra S. Steinberg
Filed: 21 Dec 20
Utility
Treatment of intrahepatic cholestatic diseases
22 Jul 21
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 3 Apr 21
Utility
Treatment of intestinal barrier dysfunction and associated diseases
20 May 21
Treatment of intestinal barrier dysfunction and associated diseases other than alcoholic liver disease or NAFLD/NASH with seladelpar or a salt thereof.
Edward E. Cable
Filed: 12 Nov 20
Utility
Treatment of alcoholic liver disease
20 May 21
Treatment of alcoholic liver disease with seladelpar or a salt thereof.
Edward E. Cable
Filed: 12 Nov 20
Utility
Methods of reducing small, dense LDL particles
18 May 21
The present invention provides methods for increasing LDL particle size.
David Karpf, Ronald M. Krauss, Yun-Jung Choi, Xueyan Wang, Francine M. Gregoire
Filed: 31 Oct 18
Utility
Treatment of intrahepatic cholestatic diseases
11 May 21
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 18 Sep 20
Utility
Treatment of NAFLD and NASH
11 Feb 21
Treatment of NAFLD and NASH by therapy with MBX-8025 or an MBX-8025 salt.
Brian Roberts, Xueyan Wang, Yun-Jung Choi, David Karpf, Robert Martin, Charles McWherter
Filed: 19 Jun 20
Utility
Treatment of intrahepatic cholestatic diseases
28 Jan 21
Treatment of intrahepatic cholestatic diseases by therapy with MBX-8025 or an MBX-8025 salt.
Pol Boudes, Charles A. McWherter
Filed: 3 Oct 20
Utility
Treatment of intrahepatic cholestatic diseases
6 Jan 21
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 17 Sep 20
Utility
Treatment of intrahepatic cholestatic diseases
6 Jan 21
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 17 Sep 20
Utility
Treatment of intrahepatic cholestatic diseases
9 Nov 20
Treatment of intrahepatic cholestatic diseases by therapy with MBX-8025 or an MBX-8025 salt.
Pol Boudes, Charles A. McWherter
Filed: 16 Dec 18
Utility
Treatment of intrahepatic cholestatic diseases
26 Oct 20
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 8 Oct 19
Utility
Treatment of intrahepatic cholestatic diseases
26 Oct 20
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
Pol Boudes, Charles A. McWherter
Filed: 5 Nov 19