107 patents
Page 3 of 6
Utility
Cancer Vaccines Targeting PRAME and Uses Thereof
25 Aug 22
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated consensus PRAME antigen.
Jian Yan, Anna Slager, Bradley Garman, Neil Cooch
Filed: 25 Apr 22
Utility
Electroporation Device Having a Battery Pack with Power Switch
16 Jun 22
An electroporation device having a battery pack including a plurality of battery cells and at least one lead in electrical communication with a circuit board.
Beat Stadelmann, Stephen Kemmerrer
Filed: 7 Mar 22
Utility
Cancer vaccines targeting PRAME and uses thereof
24 May 22
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated consensus PRAME antigen.
Jian Yan, Anna Slager, Bradley Garman, Neil Cooch
Filed: 13 Dec 18
Utility
Cancer vaccines targeting LEMD1 and uses thereof
24 May 22
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated consensus LEMD1 antigen.
Jian Yan, Anna Slager, Bradley Garman, Neil Cooch
Filed: 13 Dec 18
Utility
Device and method for single-needle in vivo electroporation
17 May 22
Described is a device and method for administration of molecules to tissue in vivo for various medical applications, the device comprising a single hypodermic injection needle and at least two spaced elongate electrodes which provide for the ability, when the needle is inserted into tissue, such as skin or muscle, to pulse tissue with a non-uniform electric field sufficient to cause reversible poration of cells lying along or in close proximity to the track made by the needle upon its insertion into said tissue.
Rune Kjeken, Iacob Mathiesen, Elisabeth Torunn Tjelle, George McHugh
Filed: 9 Jul 19
Utility
Cancer Vaccines Targeting MUC16 and Uses Thereof
14 Apr 22
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a modified consensus MUC16 antigen.
Jian YAN, Anna SLAGER, Bradley GARMAN, Neil COOCH
Filed: 22 Dec 21
Utility
Dna Antibody Constructs for Use Against Middle East Respiratory Syndrome Coronavirus
14 Apr 22
Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody to a Middle East Respiratory Syncytial Coronavirus (MERS-CoV) viral antigen.
David WEINER, Trevor RF SMITH, Kar MUTHUMANI
Filed: 23 Dec 21
Utility
DNA Antibody Constructs And Method Of Using Same
14 Apr 22
Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody.
David Weiner, Karuppiah Muthumani, Seleeke Flingai, Niranjan Sardesai
Filed: 17 Dec 21
Utility
Minimally invasive dermal electroporation device
5 Apr 22
The disclosure is directed to a device for electroporating and delivering one or more antigens and a method of electroporating and delivering one or more antigens to cells of epidermal tissues using the device.
Kate Broderick, Jay McCoy, Stephen V. Kemmerrer
Filed: 24 Apr 20
Utility
Electroporation device having a battery pack with power switch
5 Apr 22
An electroporation device having a battery pack including a plurality of battery cells and at least one lead in electrical communication with a circuit board.
Beat Stadelmann, Stephen Kemmerrer
Filed: 22 Dec 16
Utility
DNA antibody constructs and method of using same
22 Mar 22
Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody.
David B. Weiner, Karuppiah Muthumani, Seleeke Flingai, Niranjan Sardesai
Filed: 1 Dec 15
Utility
Cancer vaccines targeting MUC16 and uses thereof
1 Feb 22
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a modified consensus MUC16 antigen.
Jian Yan, Anna Slager, Bradley Garman, Neil Cooch
Filed: 13 Dec 18
Utility
DNA antibody constructs for use against middle east respiratory syndrome coronavirus
25 Jan 22
Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody to a Middle East Respiratory Syncytial Coronavirus (MERS-CoV) viral antigen.
David Weiner, Trevor R F Smith, Kar Muthumani
Filed: 27 Sep 18
Utility
Consensus Prostate Antigens, Nucleic Acid Molecule Encoding The Same And Vaccine And Uses Comprising The Same
20 Jan 22
Provided herein are consensus amino acid sequences of prostate antigens that are capable of breaking tolerance in a targeted species, including PSA, PSMA, STEAP and PSCA antigens.
David Weiner, Jian Yan, Bernadette Ferraro, Niranjan Y. Sardesai, Mathura P. Ramanathan
Filed: 28 Jun 21
Utility
Foot and Mouth Disease Virus (FMDV) Consensus Proteins, Coding Sequences Therefor and Vaccines Made Therefrom
13 Jan 22
Provided herein is a nucleic acid comprising consensus amino acid sequence of foot-and-mouth disease FMDV VP1-4 coat proteins of FMDV subtypes A, Asia 1, C, O, SAT1, SAT2, and SAT3 as well as plasmids and vaccines expressing the sequences.
David B. Weiner, Bernadette Ferraro, Jian Yan, Patricia A. Brown, Rodney A. Bowling, Douglas R. Kern, Mathura P. Ramanathan, Niranjan Y. Sardesai, Karuppiah Muthumani
Filed: 14 Sep 21
Utility
Cancer Vaccines Targeting Mesothelin and Uses Thereof
30 Dec 21
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a modified consensus mesothelin antigen.
Jian YAN, Anna SLAGER, Bradley GARMAN, Neil COOCH
Filed: 7 Sep 21
Utility
MERS-CoV Vaccine
30 Dec 21
Disclosed herein is a vaccine comprising a Middle East Respiratory Syndrome coronavirus (MERS-CoV) antigen.
David Weiner, Karuppiah Muthumani, Niranjan Y. Sardesai
Filed: 10 Sep 21
Utility
Checkpoint Inhibitor and Vaccine Combinations and Use of Same for Immunotherapy
30 Dec 21
Disclosed herein is a vaccine comprising an antigen and checkpoint inhibitor.
David Weiner, Karuppiah Muthumani, Niranjan Sardesai
Filed: 14 Sep 21
Utility
Cancer Vaccines Targeting Boris and Uses Thereof
30 Dec 21
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a synthetic consensus BORIS antigen.
Jian YAN, Anna SLAGER, Bradley GARMAN, Neil COOCH
Filed: 20 Sep 21
Utility
DNA antibody constructs and method of using same
28 Dec 21
Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody.
David Weiner, Karuppiah Muthumani, Seleeke Flingai, Niranjan Sardesai
Filed: 26 Sep 18