5 patents
Utility
Method of inhibiting tau phosphorylation
30 May 23
A method of inhibiting phosphorylation of the tau protein and/or a TLR4-mediated immune response is disclosed.
Hoau-Yan Wang, Lindsay Burns Barbier
Filed: 28 Aug 20
Utility
Blood-based Diagnostic Assays for Alzheimer's Disease
11 May 23
The invention relates to sets of biomarkers and methods of use thereof for diagnosing, staging, treating, and assessing the response of a treatment for neurocognitive disorders characterised by tau toxicity, such as Alzheimer’s disease.
Ian Pike, Michael Bremang, George Thornton
Filed: 22 Jul 22
Utility
Solid Polymorphs of a Flna-binding Compound and Its Hydrochloride Salts
27 Oct 22
The preparation and properties of crystalline polymorphs and solvates of 1-benzyl-8-methyl-1,4,8-triazaspiro-[4.5]-decan-2-one free base and of the mono-and dihydrochloride salts and solvates thereof are disclosed, as is an amorphous polymorph of the dihydrochloride.
Michael Zamloot, Lindsay Burns Barbier, Shawn Anthony Kucera
Filed: 27 Jun 22
Utility
Inhibiting an Immune Response Mediated by One or More of TLR2, Rage, CCR5, CXCR4 and CD4
28 Jul 22
A method of inhibiting an immune response mediated by one or more of TLR2, RAGE, CCR5, CXR4 and CD4 cell surface receptors of cells in recognized need is disclosed.
Hoau-Yan Wang, Lindsay Burns Barbier
Filed: 3 Nov 21
Utility
Cocrystals of naloxone and naltrexone
24 Aug 21
This invention relates to cocrystals of naloxone and of naltrexone and their use as opioid antagonists.
Remi Barbier, Nadav Friedmann, Vijay Srirambhatla, Stephen Watt, Michael Zamloot
Filed: 26 Sep 16
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