A Agilent

Agilent Technologies Inc.
Company
Patents are sorted by USPTO publication date, most recent first
GRANT
Utility
Inductively coupled plasma mass spectrometry (ICP-MS) with improved signal-to-noise and signal-to-background ratios
1 Dec 20
In an inductively coupled plasma-mass spectrometry (ICP-MS) system, ions are transmitted into a collision/reaction cell.
Noriyuki Yamada, Erina Shimizu
Filed: 13 Mar 19
APP
Utility
Use of Tri- and Tetra- Hydroxyl Quaternary Ammonium Compounds As Resolving Agents for Electrophoretic Separations
26 Nov 20
The present disclosure provides methods of improving the resolution of analytes by in electrophoretic separations using a gel by incorporating into the gel an effective amount of one or more tri- or tetra-hydroxyl quaternary ammonium compounds, or a mixture of such compounds.
Michael J. KIMZEY, Fielito U. LIMJAP, Francis T. HAXO, Sergey VLASENKO
Filed: 11 Jan 19
APP
Utility
Stable Label Isotope Tracing for Untargeted Data
19 Nov 20
A method for analyzing samples utilizing stable label isotope tracing includes receiving mass spectrometry (MS) data generated by an MS system performing untargeted data acquisition on a plurality of samples, performing untargeted feature extraction on the unlabeled compound data to generate a data set of first extracted features, generating a plurality of empirical molecular formulas respectively corresponding to the first extracted features, performing targeted isotopologue extraction on the labeled compound data to generate a data set of second extracted features, wherein the targeted isotopologue extraction is based on the empirical molecular formula and retention time of each first extracted feature, and identifying one or more groups of isotopologues from the second extracted features.
Stephen P. Madden, Steven M. Fischer
Filed: 10 Apr 20
GRANT
Utility
Temporary storage of sample portions for artefact-preventing fluid processing
10 Nov 20
In a method for processing successive fluidic sample portions provided by a sample source, sample reception volumes are filled successively temporarily with at least a respective one of the sample sections, and the sample sections are emptied successively out of the sample reception volumes in such a way, that, while emptying, it is avoided to bring two respective ones of the sample sections, which have not left the sample source directly adjacent to one another, in contact with one another.
Herbert Anderer, Konstantin Shoykhet, Klaus Witt, Stephan Buckenmaier
Filed: 28 May 15
GRANT
Utility
Systems and methods for tracking and providing workflow information
10 Nov 20
A tangible computer-readable storage device storing computer-executable program instructions that generate a user interface for displaying workflow information associated with a tissue specimen in a pathology laboratory.
Laura Chirica, Mats Grahn, Stephen Jones
Filed: 21 Aug 17
APP
Utility
Methods, Devices, and Kits to Improve Reduction or Labeling of Carbohydrates
5 Nov 20
The present invention provides methods, devices, and kits to improve procedures for reducing carbohydrates, such as glycans released from glycoconjugates, or for labeling carbohydrates by reductive amination.
Andres GUERRERO NAVARRO
Filed: 17 Sep 19
APP
Utility
Microfluidic Dielectrophoretic Droplet Extraction
5 Nov 20
A microfluidic apparatus for separating a droplet of an emulsion in a microfluidic environment is described.
Curt A. Flory, Dustin Chang
Filed: 30 Apr 19
APP
Utility
MHC Multimers In Tuberculosis Diagnostics, Vaccine and Therapeutics
5 Nov 20
The present invention relates to MHC peptide complexes and uses thereof in the diagnosis of, treatment of or vaccination against a disease in an individual.
Jørgen SCHØLLER, Liselotte BRIX, Henrik PEDERSEN, Tina JAKOBSEN
Filed: 13 Feb 20
APP
Utility
High Specificity Genome Editing Using Chemically Modified Guide RNAs
29 Oct 20
The present invention relates to guide RNAs having chemical modifications and their use in CRISPR-Cas systems.
Douglas J Dellinger, Daniel E Ryan, Subhadeep Roy, Jeffrey R Sampson
Filed: 15 Jul 20
APP
Utility
Hybridization Compositions and Methods for Making and Using Compositions
29 Oct 20
The present disclosure relates to hybridization buffers for use in hybridization, for example, for use in in situ hybridization (ISH).
Jens Mollerup
Filed: 21 Apr 20
APP
Utility
Injector with Fluid Supply and Mobile Phase Discharge
29 Oct 20
Injector (40) for injecting a fluidic sample into a mobile phase in a sample separation apparatus (10), the injector (40) comprising a main flow path (100) between a fluid drive (20) and a sample separation device (30), wherein the fluid drive (20) is adapted to drive the mobile phase and the sample separation device (30) is adapted to separate the fluidic sample that is injected into the mobile phase, a discharge device (104) for discharging an, in particular predetermined, amount of the mobile phase from the main flow path (100), and a supply device (102) for supplying an, in particular predetermined, amount of the fluidic sample and/or of a solvent into the main flow path (100), wherein the discharged amount and the supplied amount compensate each other at least partially.
Thomas Ortmann, Konstantin Shoykhet
Filed: 26 Oct 18
APP
Utility
Branching Off Fluidic Sample with Low Influence on Source Flow Path
22 Oct 20
A sample management device which comprises a source flow path in which a fluidic sample can flow, a volume flow adjustment unit configured for adjusting a volume flow of the fluidic sample to be branched off from the source flow path at a fluidic coupling point, and a fluidic valve fluidically coupled with the source flow path and with the volume flow adjustment unit, wherein the fluidic valve is switchable into a branch off state in which the fluidic coupling point is established within the source flow path to branch off an adjustable volume of the fluidic sample from the source flow path via the fluidic coupling point while a flow of the fluidic sample in the source flow path continues.
Thomas Ortmann, Daniel Thielsch, Dominik Ruf
Filed: 1 Jul 20
APP
Utility
Method and System for Determining Integrated Metabolic Baseline and Potential of Living Cells
22 Oct 20
The current technology is related to methods for rapidly determining the metabolic baseline and potential of living cells.
David A. Ferrick, Brian Dranka
Filed: 30 Jun 20
APP
Utility
Multi Frequency LC Resonator Topologies Applicable to Mass Spectrometer Radio Frequency Drive Systems
15 Oct 20
In one embodiment, a power source for providing high-voltage radio-frequency (RF) energy to an instrument such as a mass spectrometer includes an RF power amplifier having an output, an oscillating RF signal generator configured to provide first and second RF signals respectively oscillating at first and second frequencies to the RF power amplifier, and a step-up circuit for magnifying the RF power amplifier output.
Michael Schoessow
Filed: 8 Apr 20
APP
Utility
Deep Learning Based Training of Instance Segmentation via Regression Layers
15 Oct 20
Novel tools and techniques are provided for implementing digital microscopy imaging using deep learning-based segmentation and/or implementing instance segmentation based on partial annotations.
Elad Arbel, Itay Remer, Amir Ben-Dor
Filed: 10 Apr 20
APP
Utility
User Interface Configured to Facilitate User Annotation for Instance Segmentation Within Biological Sample
15 Oct 20
Novel tools and techniques are provided for implementing digital microscopy imaging using deep learning-based segmentation via multiple regression layers, implementing instance segmentation based on partial annotations, and/or implementing user interface configured to facilitate user annotation for instance segmentation.
Elad Arbel, Itay Remer, Amir Ben-Dor
Filed: 10 Apr 20
APP
Utility
Compositions and Methods for Identifying and Characterizing Gene Translocations, Rearrangements and Inversions
8 Oct 20
In alternative embodiments, provided are methods comprising use of FISH, IHC or equivalent gene fusion detection protocols, and gene sequencing, wherein optionally the gene sequencing is high throughput or next generation gene sequencing, for the identification and characterization of gene abnormalities such as gene breakages; optionally gene breakages comprise gene translocation, gene rearrangements and/or gene inversions.
Rosanne WELCHER, Mark VERARDO, Jurgen DEL FAVERO, Michael RUVOLO, Russell BALDOCCHI, Lien HEYRMAN, Dirk GOOSSENS
Filed: 31 Mar 20
APP
Utility
Mid-Infrared Scanning System for Analyzing Particulates
1 Oct 20
An apparatus and method for analyzing particulates in a sample is disclosed.
Christopher Ryan Moon, Andrew Ghetler, Matthew Kole
Filed: 30 Jan 20
APP
Utility
Hybridization Compositions and Methods
24 Sep 20
The invention provides methods and compositions for hybridizing at least one molecule to a target.
Steen Hauge Matthiesen
Filed: 7 Apr 20
GRANT
Utility
Method of oligonucleotide analysis
22 Sep 20
Described herein, among other things, is a method of estimating efficiency of an oligonucleotide synthesis reaction.
Joel Myerson
Filed: 6 Feb 17