A Agilent

Agilent Technologies, Inc.
Company
Patents are sorted by USPTO publication date, most recent first
APP
Utility
Compositions and Methods for Genomic Dna and Gene Expression Analysis In Single Cells
9 Jul 20
Provided herein are compositions and methods to assess the genomic landscape of fixed cells using light activated oligonucleotides that can be directed to the nucleus, mitochondria, or cytoplasm of fixed cells and that, upon activation, can be extended for in situ copying of nuclear single-stranded DNA (i.e., open chromatin), open mitochondrial DNA, and/or cytoplasmic RNA into barcoded complementary DNA.
James EBERWINE, Jae-Hee LEE, Jifen LI, Stephen FISHER, Youtao LU, Junhyong KIM, Jai-Yoon SUL, Jinchun WANG, Mimi HEALY
Filed: 7 Jan 20
GRANT
Design
Chromatograph
7 Jul 20
Richard P. White, Robert James Collins, Rafael Mulero, Edward D. Mroz, Thomas Harrison, Manuela Senf, Cathrin Sohns, Fanny Hauser
Filed: 2 Nov 18
APP
Utility
Multipole Ion Optic Assembly
2 Jul 20
An ion optic assembly includes a set of conductive rods, a first insulator, and a second insulator.
Robert M. Roberts, James L. Bertsch
Filed: 17 Dec 19
GRANT
Utility
Device and method of a supercritical fluid system for detecting analytes using a low pressure detector
30 Jun 20
A device is provided in a supercritical fluid system, which uses a mobile phase output by a separation device, the mobile phase volumetrically expanding as it decompresses.
Edwin E. Wikfors
Filed: 25 Jun 15
GRANT
Utility
Hairpin-mediated amplification method
30 Jun 20
In some embodiments, the amplification method may comprise producing a reaction mix comprising: a nucleic acid sample, a polymerase, nucleotides, a forward primer that hybridizes to a sequence in the bottom strand of a fragment in the sample, and a reverse primer.
Brian Jon Peter, Robert A. Ach
Filed: 31 Aug 17
APP
Utility
Molecular Fabrication
25 Jun 20
Provided herein is a method for fabricating transformable or transfectable molecules that includes an assembly reaction containing a variety of pre-made cassettes possessing ends that hybridize to one another, transforming or transfecting said molecules into a desired host cell and then selecting a transformed/transfected host cell containing plasmid molecules composed of said the cassettes.
Jeffrey Carl Braman, Peter James Sheffield, Gavin Fischer
Filed: 28 Feb 20
APP
Utility
Deparaffinization of Tissue by Electric Field Generation and Ionization
25 Jun 20
Paraffin-embedded tissue, which may be disposed on a solid substrate, is prepared by a dry technique that removes paraffin from tissue without adding any liquid to the tissue, thereby rendering the tissue substantially free of paraffin.
Victor Lim, Carol T. Schembri, Adrienne Mccampbell, Nazumi Alice Yama-Dang
Filed: 27 Feb 20
APP
Utility
Scoring Methods for Anti-pd Therapy Eligibility and Compositions for Performing Same
25 Jun 20
Aspects of the present disclosure provide methods for determining the eligibility of a subject having a malignancy for treatment with an anti-PD therapeutic agent based on a Combined Positive Score (CPS) for a tumor tissue sample from the subject.
Karina Kulangara, Nancy Zhang, David Stanforth, Greg Angelides, Stephanie Waldroup, Kenneth Emancipator
Filed: 28 Feb 20
GRANT
Design
Chromatograph
23 Jun 20
Ping Hu, Fanny Hauser, Qian Tao, Cathrin Sohns, Qi Siegmundt-Pan, Maximilian Schneider, Robert James Collins, Thomas Harrison, Edward D. Mroz, Rafael Mulero, Richard P. White
Filed: 2 Nov 18
GRANT
Utility
Pairing code directed assembly
23 Jun 20
Jeffrey Robert Sampson, Derek Lee Lindstrom
Filed: 16 Apr 18
APP
Utility
Orthoester Compositions for Affinity Purification of Oligonucleotides
18 Jun 20
Compounds and methods for purifying oligonucleotides such as RNA and DNA.
Douglas J. DELLINGER, Joel MYERSON, Brian SMART
Filed: 17 Aug 18
GRANT
Utility
Preparation of tissue sections using fluorescence-based detection
16 Jun 20
The present disclosure is directed to an improved method for distinguishing tissue from an embedding medium, such as paraffin in a formalin-fixed paraffin-embedded sample.
Kyle Schleifer, Kristin Briana Bernick, Adrienne Mccampbell, Nicholas M Sampas, Victor Lim
Filed: 1 Jun 18
APP
Utility
Orthoester Compositions for Affinity Purification of Oligonucleotides
11 Jun 20
Compounds and methods for purifying oligonucleotides such as RNA and DNA.
Douglas J. DELLINGER, Joel MYERSON, Brian SMART
Filed: 18 Feb 20
APP
Utility
Assay Methods and Compositions for Detecting Contamination of Nucleic Acid Identifiers
11 Jun 20
The present invention relates to nucleic acid samples for massively parallel sequencing.
Katie Leigh Zobeck, Paige Anderson, Javelin Chi, Henrik Johansson
Filed: 17 Feb 20
APP
Utility
Method for Fragmenting Genomic DNA Using CAS9
4 Jun 20
A method for fragmenting a genome is provided.
Brian Jon Peter, Robert A. Ach, Michael Walter, Bram Herman
Filed: 21 Jan 20
APP
Utility
Real-Time Cellular or Pericellular Microenvironmental Oxygen Control
28 May 20
A method of maintaining an intracellular oxygen concentration of viable cells forming a cell sample at a target oxygen concentration or maintaining a micro-environmental pericellular space defined by a cell sample of viable cells at a target oxygen concentration, particularly throughout a testing period, by measuring intracellular/pericellular oxygen concentration and adjusting the concentration of oxygen in the surrounding environment in real-time based upon the measured intracellular/pericellular oxygen concentration as necessary and appropriate to influence and maintain the intracellular/pericellular oxygen concentration at a desired target oxygen concentration.
Ian M. Hayes, James N. Hynes
Filed: 10 May 18
GRANT
Design
Chromatograph
26 May 20
Ping Hu, Fanny Hauser, Cathrin Sohns, Qi Siegmundt-Pan, Maximilian Schneider
Filed: 14 Nov 18
GRANT
Utility
Synthetic silica as packing material in supported liquid extraction
26 May 20
In embodiments, a packing material for supported liquid extraction has a sorbent media that includes synthetic silica particles.
Kunqiang Jiang, Derick Lucas, Bruce Richter
Filed: 19 Dec 18
GRANT
Utility
Molecular fabrication
26 May 20
Provided herein is a method for fabricating transformable or transfectable molecules that includes an assembly reaction containing a variety of pre-made cassettes possessing ends that hybridize to one another, transforming or transfecting said molecules into a desired host cell and then selecting a transformed/transfected host cell containing plasmid molecules composed of said the cassettes.
Jeffrey Carl Braman, Peter James Sheffield, Gavin Fischer
Filed: 2 Oct 13
GRANT
Utility
Hybridization compositions and methods using formamide
26 May 20
The invention provides methods and compositions for hybridizing at least one molecule to a target.
Steen Hauge Matthiesen
Filed: 28 Sep 12