451 patents
Page 13 of 23
Utility
Filters for liquid flow based devices and systems
19 Oct 21
A filter includes an inlet side, an outlet side, and a body.
Qing Bai, Ares Geovanos, Hongfeng Yin, Thor Miller Wilbanks
Filed: 22 Dec 17
Utility
Assay Methods and Compositions for Detecting Contamination of Nucleic Acid Identifiers
14 Oct 21
The present invention relates to nucleic acid samples for massively parallel sequencing.
Katie Leigh Zobeck, Paige Anderson, Javelin Chi, Henrik Johansson
Filed: 2 Jun 21
Utility
User interface configured to facilitate user annotation for instance segmentation within biological samples
12 Oct 21
Novel tools and techniques are provided for implementing digital microscopy imaging using deep learning-based segmentation via multiple regression layers, implementing instance segmentation based on partial annotations, and/or implementing user interface configured to facilitate user annotation for instance segmentation.
Elad Arbel, Itay Remer, Amir Ben-Dor
Filed: 10 Apr 20
Utility
Quick lock connector for connecting a capillary to a fluidic conduit of a fluidic component
5 Oct 21
A fitting for providing a fluid connection between a capillary and a fluidic conduit of a fluidic component, wherein the fitting comprises a capillary reception configured for receiving the capillary, a force applicator configured for being operable to apply a fixing force for fixing the capillary within the fitting, a force limitation mechanism configured for limiting the fixing force being applicable by the force applicator to the capillary, a force splitter configured for splitting the fixing force into an advance force component for advancing the capillary received in the capillary reception towards the fluidic component and into a clamping force component for clamping the capillary received in the capillary reception within the fitting, and a biasing mechanism particularly arranged between the force applicator and the force splitter and configured for biasing the force splitter against the capillary.
Darijo Zeko, Jose-Angel Mora-Fillat
Filed: 8 Aug 17
Utility
Systems and Methods for Electronically and Optically Monitoring Biological Samples
30 Sep 21
A system for electronically and optically monitoring biological samples, the system including: a multi-well plate having a plurality of wells configured to receive a plurality of biological samples, each of the wells having a set of electrodes and a transparent window on a bottom surface of the well that is free of electrodes; an illumination module configured to illuminate the wells; a cradle configured to receive the multi-well plate, the cradle having an opening on the bottom that exposes the transparent windows of the wells; and an optical imaging module movable across different wells of a same multi-well plate to capture images through the windows.
Nan Li, Xin Yao, Longbin Fang, Lingbo Kong, Qiting Ye, Caixia Yang, Brandon Lamarche, Xiaobo Wang
Filed: 29 Mar 20
Utility
Method and System for Estimating Whether a Female Is Pregnant Based on a Blood Sample
30 Sep 21
A method for estimating whether a female is pregnant, said method comprising measuring allele presences (D) for a plurality of genetic markers of at least one chromosome, different from the X and Y chromosome, in a sample of cell-free DNA from a potentially pregnant female; each allele presence representing the presence at a genetic marker of at least one of: a reference allele of maternal or foetal origin, and an alternative allele of maternal or foetal origin; based on said measured allele presences, determining a homozygous fraction (Fho) thereof which is associated with purely homozygous genetic markers; and estimating whether the female is pregnant based on said fraction.
Jurgen Peter Lode DEL FAVERO, Michaƫl VYVERMAN, Paul VAUTERIN
Filed: 11 Jun 21
Utility
Adjusting Separation Method Using Sensor Data and Numerical Analysis
30 Sep 21
A process of determining a modified separation method for a sample separation apparatus based on an initial separation method, including carrying out the initial separation method on a sample separation apparatus, detecting sensor data at the sample separation apparatus during carrying out the initial separation method, and carrying out a numerical analysis for determining the modified separation method by modifying at least one operation parameter of the initial separation method and by using the detected sensor data.
Bettina Schuhn, Uwe Effelsberg
Filed: 29 Mar 21
Utility
Ion Source
30 Sep 21
Provided herein is an ion source containing a plurality of components, at least one of which is partially coated with a layer of silicon.
Bruce D. Quimby, Anastasia A. Andrianova
Filed: 26 Mar 20
Utility
Hybridization compositions and methods
14 Sep 21
The invention provides methods and compositions for hybridizing at least one molecule to a target.
Steen Hauge Matthiesen, Kenneth H. Petersen, Tim Svenstrup Poulsen, Charles M. Hansen
Filed: 27 May 09
Utility
Hybridization compositions and methods
14 Sep 21
The invention provides methods and compositions for hybridizing at least one molecule to a target.
Steen Hauge Matthiesen
Filed: 22 Oct 12
Design
Spectrophotometer
7 Sep 21
Dale Hathaway, Daniela Loraing, Maximilian Schneider, Craig Peters, Stuart Bonthron, Scott Harwood
Filed: 1 Jul 19
Utility
Methods, kits and compositions pertaining to the suppression of the detectable probe binding to randomly distributed repeat sequences genomic nucleic acid
7 Sep 21
This invention is directed to methods, kits, non-nucleotide probes as well as other compositions pertaining to the suppression of binding of detectable nucleic acid probes to undesired nucleotide sequences of genomic nucleic acid in assays designed to determine target genomic nucleic acid.
Kirsten Vang Nielsen, Jens Hyldig-Nielsen, Brett F. Williams
Filed: 19 Mar 18
Utility
Use of quaternary and tertiary ammonium cations to denature proteins
7 Sep 21
Ammonium cation detergents comprising a quaternary or tertiary ammonium cation can be used as detergents to denature proteins and are particularly useful in denaturing glycoproteins or glycopeptides prior to enzymatic deglycosylation.
Michael J. Kimzey, Francis T. Haxo, Vaishali Sharma
Filed: 17 Aug 17
Utility
Restriction Mediated Quantitative Polymerase Chain Reactions
2 Sep 21
The present invention relates to the technical field of nucleic acid amplification using a Polymerase Chain Reaction (PCR).
Jurgen DEL FAVERO
Filed: 10 Feb 21
Utility
Unions and Couplers
2 Sep 21
One aspect of the invention provides a gas chromatography union including: a first port; a second port in fluid communication with the first port; and a first pair of wings defining a first recess.
Allen K. Vickers, Ngoc A Thi Dang, David Jantz
Filed: 28 Feb 20
Utility
Phosphorous protecting groups and methods of preparation and use thereof
31 Aug 21
Aspects of the present disclosure include compositions that make use of phosphorus and/or nucleobase protecting groups which find use in the synthesis of long polynucleotides.
Douglas J. Dellinger, Luca Monfregola, Marvin Caruthers, Mithun Roy
Filed: 29 Oct 18
Utility
Use of Mild Electrophiles to Reduce Artifacts in Analyzing Glycans Released from Glycoproteins or Glycopeptides
26 Aug 21
The presence of mild electrophiles, such as aldehydes, during the denaturation of glycoproteins or glycopeptides and subsequent enzymatic deglycosylation reduces artifacts in subsequent analyses of the glycans released from the glycoproteins or gly-copeptides.
Michael J. Kimzey
Filed: 13 May 21
Utility
Use of bispyridines to improve labeling of nucleophiles
17 Aug 21
Bispyridines improve the labeling of nucleophiles, including amines and thiols and are particularly useful for improving labeling with acidic and basic labels.
Francis T. Haxo, Michael J. Kimzey
Filed: 24 Feb 17
Utility
ICP spectroscopy torch with removable one-piece injector
10 Aug 21
A torch for use in analytic instruments includes a tube subassembly with substantially cylindrical nested inner and outer tubes with coincident central axes, the inner tube having a terminus.
Luke Sparkes
Filed: 11 Jun 19
Utility
Methods and apparatus to facilitate gravitational cell extraction
3 Aug 21
The invention relates generally to methods and apparatus that gravitationally transfer cells from a first medium to a second medium.
Curt A. Flory, Dustin Chang, Pallevi Srivastva, Rolfe Anderson
Filed: 2 Jul 19