451 patents
Page 3 of 23
Utility
Compositions and methods for performing hybridizations with separate denaturation of the sample and probe
24 Oct 23
The invention provides methods and compositions for separately denaturing a probe and target in hybridization applications.
Steen Hauge Matthiesen
Filed: 4 Jan 19
Design
Headspace sampler
24 Oct 23
Sammye Elizabeth Traudt, Fanny Hauser, Thomas E. Price, Jonathan Michael Frentzel
Filed: 18 Feb 21
Utility
Antibodies for Use In Immunohistochemistry (Ihc) Protocols to Diagnose Cancer
19 Oct 23
In alternative embodiments, provided are chimeric or recombinant rabbit antihuman p40 (p63 isoform DeltaNp63, or ΔNp63) antibodies, including products of manufacture and kits comprising them, and methods for making and using them, where the antibodies can be used for in vitro diagnostics by immunohistochemistry (IHC).
Morten Dræby SØRENSEN, Lasse RAMSGAARD
Filed: 25 Aug 21
Utility
Valve arrangement having valve module and base module
17 Oct 23
A valve arrangement includes a valve module and a base module.
Manfred Berndt
Filed: 11 Jul 19
Utility
Axially progressive lens for transporting charged particles
17 Oct 23
An electrostatic lens for transporting charged particles in an axial direction includes a first group of first electrodes configured to receive a first DC potential from a DC voltage source, and a second group of second electrodes configured to receive a second DC potential from the DC voltage source different from the first DC potential.
Tong Chen, Curt A. Flory, Gershon Perelman
Filed: 16 Jul 20
Utility
Orthoester Compositions for Affinity Purification of Oligonucleotides
12 Oct 23
Compounds and methods for purifying oligonucleotides such as RNA and DNA.
Douglas J. DELLINGER, Joel MYERSON, Brian SMART
Filed: 21 Oct 22
Utility
Vacuum pump with elastic spacer
10 Oct 23
A vacuum pump includes a housing, a rotatable shaft extending in an axial direction within the housing, a first pumping arrangement including a first stator arrangement and a first rotor arrangement, and a second pumping arrangement including a second stator arrangement and a second rotor arrangement.
Federico Terminio, Simone Cau
Filed: 1 Dec 21
Utility
Resistive Coating for a Capillary
5 Oct 23
A coated capillary tube having a tunable resistance in an ion transfer device, including an inlet end in communication with an atmospheric-pressure ion source, an outlet end in communication with a vacuum region of a mass spectrometer, a body elongated along an axis from the inlet end to the outlet end, and an inside surface defining a bore having an inner diameter is disclosed.
Elizabeth CARR, Richard G. CLOSSER
Filed: 29 Sep 21
Utility
Fluid valve having a coating containing gold and/or platinum
3 Oct 23
A fluid valve for a sample separation apparatus includes a first valve component and a second valve component, which are adjacent to one another and movable relative to one another.
Tony Ziegler, Darijo Zeko, Thomas Ortmann
Filed: 23 Jan 18
Utility
Combined degassing and circulation of liquid
3 Oct 23
A degasser for at least partially degassing a gas-containing liquid, in particular for a sample separation device, includes a circulation path along which the liquid can be circulated between a liquid accommodation volume and one of an inlet to a consumer unit consuming degassed liquid or a conduit leading to the inlet, a drive unit configured for circulating the liquid in the circulation path, and a filter in the circulation path for filtering particles or debris out of the liquid, wherein the liquid is forced through the filter by the drive unit.
Konstantin Shoykhet
Filed: 3 Feb 20
Utility
Polymerase mutants and use with 3′-OH unblocked reversible terminators
3 Oct 23
Mutant polymerases are provided that have improved ability to incorporate modified nucleotides, including 3′-OH unblocked reversible terminators.
Michelle Cayouette, Jeffrey Fox, Connie Hansen, Holly Hogrefe, Weidong Wu
Filed: 24 Aug 22
Utility
Method of Producing Etched Non-porous Particles
28 Sep 23
There is disclosed a method of producing etched non-porous particles.
Ta-Chen WEI
Filed: 18 May 23
Utility
Valve with Axial Angle Compensation
21 Sep 23
A valve may be utilized in a high-performance chromatography system for separating components of a sample liquid introduced into a mobile phase.
Thomas Ortmann, Blasius Nocon, Armin Steinke, Christian Daniel Ruf
Filed: 29 Jul 21
Utility
Freeform Collimator Lens for Angled Facet Laser Devices
21 Sep 23
An apparatus having a waveguide and a freeform collimating lens.
Guthrie Partridge, Joao Mendes-Lopes
Filed: 12 Aug 21
Utility
Real Time Electronic Cell Sensing Systems and Applications for Cell-based Assays
14 Sep 23
Methods for identifying compounds that modulate cellular responses stimulated by IgE, which include providing an impedance-based system that monitors cell-substrate impedance of cells on a substrate; introducing cells to the substrate of the system; adding at least one test compound and IgE to the cells, wherein the at least one test compound is suspected of modulating cell responses stimulated by the IgE; adding an antigen to the cells; monitoring the cell-substrate impedance of cells on the substrate; and analyzing the cell-substrate impedance to evaluate whether the at least one test compound alters a cellular response to stimulation with the IgE.
Xiao Xu, Yama A. Abassi, Xiaobo Wang, Jiangbo Gan
Filed: 8 Mar 23
Utility
Pipette Tip Devices and Methods
14 Sep 23
Methods and apparatus are provided for attaching and detaching pipette tips with a pipettor and for storing pipette tips.
Richard Avidano
Filed: 14 May 21
Utility
Methods and systems for functional maturation of iPSC and ESC derived cardiomyocytes
5 Sep 23
Methods of inducing functional maturation of immature cardiomyocytes derived from induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) by electrically pacing the immature cardiomyocytes according to a pulse profile that induces maturation until the immature cardiomyocytes mature into functionally adult cardiomyocytes.
Xiaoyu Zhang, Yama A. Abassi, Nan Li, Xiaobo Wang
Filed: 3 Mar 18
Utility
Gas leak detector cartridge
5 Sep 23
A gas leak detector cartridge includes a cartridge housing that is removably installed in a handheld device.
Chin-Seong Khor, Jon-Wen Tan, Heng-Dar Ling
Filed: 28 Sep 20
Utility
Deep learning based instance segmentation via multiple regression layers
5 Sep 23
Novel tools and techniques are provided for implementing digital microscopy imaging using deep learning-based segmentation and/or implementing instance segmentation based on partial annotations.
Elad Arbel, Itay Remer, Amir Ben-Dor
Filed: 23 Jun 22
Utility
Apparatuses and Methods for Analyzing Live Cells
17 Aug 23
An analytical instrument having a sensing system, a stage adapted to receive a sample carrier, a motion actuator assembly for positioning the sensing system and/or the stage, a temperature control element, and a signal processing module are disclosed.
Andrew C. Neilson, Jason Dell'Arciprete, Eric John Schultz, Brady Robert Paradis, George W. Rogers, Yoonseok Kam
Filed: 3 Feb 23