451 patents
Page 4 of 23
Utility
Microfluidic Component with Metal Layer Stack and Fluid Conduit Element Made of Another Material Bonded with It
17 Aug 23
A microfluidic component for a sample separation device includes a layer body with multiple metal layer structures that are connected with each other, and an element made of a material different from the metal layer structures, which includes at least one microfluidic structure and is bonded with the layer body.
Armin Steinke, Christian Daniel Ruf
Filed: 9 Jun 21
Utility
Instrument Monitoring System
17 Aug 23
Systems and methods are disclosed for capturing and interpreting data streams between an instrument and a controlling device.
Rick Fasani
Filed: 30 Jun 21
Utility
Amplifying oligonucleotides and producing libraries of dual guide constructs
8 Aug 23
Methods and compositions are provided for amplifying a pool of oligonucleotides, such as dual guide oligonucleotide constructs comprising sequences encoding a first guide RNA segment and a sequence encoding a second guide RNA segment.
Jeffrey Carl Braman, Peter James Sheffield, Holly Hogrefe
Filed: 29 Aug 18
Utility
Phosphopeptide-encoding oligonucleotide libraries and methods for detecting phosphorylation-dependent molecular interactions
8 Aug 23
The present invention relates to libraries of phosphopeptide-encoding oligonucleotides and methods of preparing such libraries.
Jesse Rinehart, Karl Barber, Farren Isaacs, Jeffrey R Sampson
Filed: 18 Feb 19
Utility
Lamp-housing Assembly with Axially and Radially Aligned and Electrically Coupled Elements
3 Aug 23
A lamp-housing assembly, for a detector of a sample separation apparatus for separating a fluidic sample, includes a lamp seat, a lamp insertable into the lamp seat, and a lamp cap mountable on the lamp seat and on the inserted lamp.
Christian Hirn, Christoph Keppler
Filed: 19 Dec 22
Utility
Systems and Methods for Electronically and Optically Monitoring Biological Samples
27 Jul 23
A system for electronically and optically monitoring biological samples, the system including: a multi-well plate having a plurality of wells configured to receive a plurality of biological samples, each of the wells having a set of electrodes and a transparent window on a bottom surface of the well that is free of electrodes; an illumination module configured to illuminate the wells; a cradle configured to receive the multi-well plate, the cradle having an opening on the bottom that exposes the transparent windows of the wells; and an optical imaging module movable across different wells of a same multi-well plate to capture images through the windows.
Nan Li, Xin Yao, Longbin Fang, Lingbo Kong, Qiting Ye, Caixia Yang, Brandon Lamarche, Xiaobo Wang
Filed: 31 Mar 23
Utility
Systems and Methods for Coverslipping Slides
27 Jul 23
Systems and methods for coverslipping a sample on a slide employ a coverslip tape.
Rolfe Anderson, Adrienne Mccampbell, Victor Lim, Carol T. Schembri, Michal Johannsen, Fleming Lassen Nielsen
Filed: 11 Jun 21
Utility
Method and Apparatus for Measuring Physiological Properties of Biological Samples
20 Jul 23
The present disclosure relates to methods and apparatus for measuring of multiple physiological properties of biological samples, such as measuring biological flux.
Andrew C. Neilson, Paul D. McGarr
Filed: 27 Mar 23
Utility
Optical spectrometer modules, systems and methods for optical analysis with multiple light beams
18 Jul 23
A method of optical analysis comprises receiving light at an optical spectrometer module from a light source, distributing the received light into two or more light beams with a light distribution component of the optical spectrometer module, concurrently exposing each of a reference and one or more test samples to one of the two or more light beams, and concurrently measuring a property of the light associated with each of the reference sample and one or more test samples with a corresponding detector.
Hugh Charles Stevenson, David Death, Eran Lande
Filed: 16 Jan 18
Utility
Metal Components with Inert Vapor Phase Coating on Internal Surfaces
13 Jul 23
The invention provides metal liquid chromatography components with uniformly coated internal surfaces and methods for achieving the same.
Elizabeth CARR, Karen L. SEAWARD, Kevin P. KILLEEN
Filed: 22 Mar 23
Utility
Sampling with Fitting Between Needle and Housing
6 Jul 23
A sampling unit includes a needle for aspirating a sample fluid, a housing, and a fitting.
Thomas Ortmann, Michael Lang
Filed: 22 Jun 21
Utility
Pipette Tip Washing Devices and Methods
6 Jul 23
Methods and apparatus are provided for washing pipette tips, including the inside and outside of the pipette tip.
Cyrille Shkolnik, Eric Spence, Brian M. Sheldon, Dennis Garcia, Andy Wu
Filed: 30 Apr 21
Utility
Chimeric Primers and Related Methods
6 Jul 23
The present disclosure provides chimeric primers suitable for use in the amplification of a nucleic acid sequence.
Jurgen DEL FAVERO, Lien HEYRMAN, Dirk GOOSSENS, Bart TEGENBOS
Filed: 30 Dec 20
Utility
Apparatus and Method for Processing Biological Samples
6 Jul 23
Method and apparatus are provided for processing a sample on a slide.
Michal Johannsen, Steen Hauge Matthiesen, Peter Valbjørn, Martin Lindberg
Filed: 26 May 21
Utility
Drive shaft connector with counterweight and blades for cooling pump motor
27 Jun 23
A fluid pump includes a pump head and a motor coupled by a drive shaft.
Vannie Lu, George Galica, Aileen Cheang
Filed: 7 Jun 22
Utility
Digital Analysis of Preanalytical Factors In Tissues Used for Histological Staining
25 May 23
There is provided a computer implemented method of training a preanalytical factor machine learning model, comprising: creating a preanalytical training dataset of a plurality of records, wherein a preanalytical record comprises: an image of a slide of pathological tissue of a subject processed with at least one preanalytical factor, and a ground truth label indicating the at least one preanalytical factor, and training the preanalytical machine learning model on the preanalytical training dataset for generating an outcome of at least one target preanalytical factor used to process tissue depicted in a target image in response to the input of the target image.
Frederik AIDT, Oded BEN-DAVID, Lars Christian JACOBSEN
Filed: 23 Nov 22
Utility
Methods and Systems for Sensing Headspace Vial Presence
25 May 23
Methods and systems for sensing headspace vial presence are described herein.
Jonathan Michael FRENTZEL, Thomas E. PRICE, Jared M. BUSHEY, Paul C. DRYDEN
Filed: 9 Apr 21
Utility
Scoring Methods for Anti-pd Therapy Eligibility and Compositions for Performing Same
18 May 23
Aspects of the present disclosure provide methods for determining the eligibility of a subject having a malignancy for treatment with an anti-PD therapeutic agent based on a Combined Positive Score (CPS) for a tumor tissue sample from the subject.
Karina Kulangara, Nancy Zhang, David Stanforth, Greg Angelides, Stephanie Waldroup, Kenneth Emancipator
Filed: 18 Jan 23
Utility
Real Time Electronic Cell Sensing Systems and Applications for Cell-based Assays
11 May 23
Methods for identifying compounds that modulate cellular responses stimulated by IgE, which include providing an impedance-based system that monitors cell-substrate impedance of cells on a substrate; introducing cells to the substrate of the system; adding at least one test compound and IgE to the cells, wherein the at least one test compound is suspected of modulating cell responses stimulated by the IgE; adding an antigen to the cells; monitoring the cell-substrate impedance of cells on the substrate; and analyzing the cell-substrate impedance to evaluate whether the at least one test compound alters a cellular response to stimulation with the IgE.
Xiao Xu, Yama A. Abassi, Xiaobo Wang, Jiangbo Gan
Filed: 10 Jan 23
Utility
System and method of data-dependent acquisition by mass spectrometry
9 May 23
Systems, computer-readable media, and methods using mass spectrometry to analyze a sample are provided.
Javier E. Satulovsky
Filed: 20 Dec 19