ILMN Illumina

Illumina, Inc.
Company
Patents are sorted by USPTO publication date, most recent first
APP
Utility
Spatial Indexing of Genetic Material and Library Preparation Using Hydrogel Beads and Flow Cells
9 Jul 20
Implementations of a method for seeding sequence libraries on a surface of a sequencing flow cell that allow for spatial segregation of the libraries on the surface are provided.
Tarun Kumar Khurana, Yir-Shyuan Wu, Xi-Jun Chen, Filiz Gorpe-Yasar, Yan-You Lin, Victoria Popic, Erich B. Jaeger, Mostafa Ronaghi
Filed: 31 Jul 18
APP
Utility
Fluid Management System and Method
9 Jul 20
A fluid detection system includes a wicking material to draw fluid away from a first location with space limitations and proximate to a fluid device or a fluid interface.
Gregory L. Holst, Jay Taylor
Filed: 3 Jan 20
APP
Utility
Flow Cell Liquid Degassing System and Method
9 Jul 20
A system utilizes a flow cell for holding an analyte of interest for examination, such as a genetic material to be imaged for sequencing.
Bradley Kent Drews
Filed: 13 Mar 20
APP
Utility
Pattern Angle Spatial Selection Structured Illumination Imaging
9 Jul 20
The disclosure provides for structured illumination microscopy (SIM) imaging systems.
Peter Clarke Newman, Danilo Condello, Shaoping Lu, Simon Prince, Merek C. Siu, Stanley S. Hong, Aaron Liu
Filed: 14 Jan 19
APP
Utility
Multi-Arm Structured Illumination Imaging
9 Jul 20
The disclosure provides for structured illumination microscopy (SIM) imaging systems.
Stanley S. Hong
Filed: 14 Jan 19
APP
Utility
Methods for Improving Polynucleotide Cluster Clonality
2 Jul 20
The present invention is concerned with compositions and methods for improving the generation of monoclonal clusters in an array by tuning the degree of homology between target nucleic acid adapters and the primers attached to the array to encode a kinetic delay into seeded target nucleic acids.
Jeffrey S. Fisher, Minghao Guo
Filed: 18 Dec 19
APP
Utility
Systems and Methods Including a Rotary Valve for at Least One of Sample Preparation or Sample Analysis
2 Jul 20
Systems and methods for conducting designated reactions that include a fluidic network having a sample channel, a reaction chamber, and a reservoir.
Sebastian Bohm, Alex Aravanis, Alexander Hsiao, Behnam Javanmardi, Tarun Khurana, Hai Quang Tran, Majid Aghababazadeh, M. Shane Bowen, Boyan Boyanov, Dale Buermann
Filed: 13 Mar 20
APP
Utility
Methods and Compositions Using One-sided Transposition
2 Jul 20
Embodiments provided herein relate to methods and compositions for next generation sequencing.
Frank J. Steemers, Jeffrey S. Fisher, Kevin L. Gunderson, Sasan Amini, Christian Gloeckner
Filed: 7 Jan 20
GRANT
Utility
Modified polymerases for improved incorporation of nucleotide analogues
30 Jun 20
Presented herein are polymerase enzymes for improved incorporation of nucleotide analogues, in particular nucleotides which are modified at the 3′ sugar hydroxyl, as well as methods and kits using the same.
Erin Bomati, Michael Previte, Matthew William Kellinger, Cheng-Yao Chen, Molly He
Filed: 28 Nov 18
APP
Utility
Nuclease-based Rna Depletion
25 Jun 20
The present disclosure is related to methods and materials for depleting unwanted RNA species from a nucleic acid sample.
Scott Kuersten, Frederick W. Hyde, Asako Tetsubayashi
Filed: 19 Dec 19
APP
Utility
Sequencing System with Multiplexed Biological Sample Aggregation
25 Jun 20
A wide variety of scenarios are supported for per-biosample aggregation of sequencing yield.
Eric Smith, James Bierle, Sean Kim, Tyler Aragon, Pedro Cruz, Rodger Constandse
Filed: 25 Jul 18
APP
Utility
Polynucleotide Amplification Using Crispr-cas Systems
25 Jun 20
A method for amplifying a target nucleic acid including providing a system having a crRNA or a derivative thereof, and a Cas protein or a variant thereof.
Jeffrey G. Mandell
Filed: 6 Jan 20
APP
Utility
Sensing Systems
25 Jun 20
A sensing system includes a charge sensor including two electrodes and an electrically conductive channel connecting the two electrodes.
Boyan Boyanov, Sergio Peisajovich, Jeffrey G. Mandell
Filed: 3 Dec 19
GRANT
Utility
Fluidic devices and methods of manufacturing the same
23 Jun 20
An example method includes providing a working stack having a first substrate layer, a second substrate layer, and a radiation-absorbing material disposed between the first and second substrate layers.
John Gerhardt Earney, Justin Fullerton, Kaleb Smith, Bala Murali K. Venkatesan
Filed: 12 Dec 17
GRANT
Utility
Methods and systems for analyzing image data
23 Jun 20
Methods and systems for analysis of image data generated from various reference points.
Paul Belitz, Stephen Tanner, John S. Vieceli, Xiaoyu Chen
Filed: 3 Dec 14
APP
Utility
Methods and Compositions for Addressing Inefficiencies In Amplification Reactions
18 Jun 20
Methods and systems for decreasing amplification bias and primer-dimer formation in amplification reactions and for amplifying a plurality of target polynucleotides from a sample in a single reaction and for sequencing the target polynucleotides where samples can include forensic samples and where target polynucleotides can include identity- or ancestry-informative markers, short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs).
Jon-Matthew Belton, Johann Felix Schlesinger, Siarhei Manakou, Amanda Garfinkel Young
Filed: 13 Jun 18
APP
Utility
Array Including Sequencing Primer and Non-sequencing Entity
18 Jun 20
An example of an array includes a support including a plurality of discrete wells, a gel material positioned in each of the discrete wells, a sequencing primer grafted to the gel material, and a non-sequencing entity grafted to the gel material.
James TSAY, Yuxiang HUANG
Filed: 20 Dec 17
APP
Utility
Hybrid Nanopore Sensors
18 Jun 20
The disclosure provides detection apparatus having one or more nanopores, methods for making apparatus having one or more nanopore and methods for using apparatus having one or more nanopores.
BOYAN BOYANOV, JEFFREY G. MANDELL, KEVIN L. GUNDERSON, JINGWEI BAI, LIANGLIANG QIANG, BRADLEY BAAS
Filed: 9 Dec 19
APP
Utility
Flow Cells and Sequencing Kits
18 Jun 20
In one example, a flow cell includes a substrate, an electrode positioned on the substrate, and a patterned material positioned on the electrode.
Hayden Black, Brian D. Mather
Filed: 3 Dec 19
GRANT
Utility
Substrates comprising nano-patterning surfaces and methods of preparing thereof
16 Jun 20
Substrates comprising a functionalizable layer, a polymer layer comprising a plurality of micro-scale or nano-scale patterns, or combinations thereof, and a backing layer and the preparation thereof by using room-temperature UV nano-embossing processes are disclosed.
M. Shane Bowen, Bala Murali Venkatesan, Steven M. Barnard
Filed: 17 Dec 14