718 patents
Utility
Dynamically Selecting Sequencing Subregions for Cancer Classification
18 Jan 24
Methods and systems for segmenting sequencing regions obtained from a sample interval are disclosed. sample contamination detection are disclosed.
Qinwen Liu, Frank Chu
Filed: 18 Jul 23
Utility
Long Indexed-linked Read Generation on Transposome Bound Beads
18 Jan 24
Embodiments of systems, methods, and compositions provided herein relate to on bead tagmentation and droplet indexing.
Lena Christiansen, Frank J. Steemers, Gary Schroth, Jerushah Thomas, Dmitry K. Pokholok
Filed: 26 Jul 23
Utility
In-tip Magnetic-based Magnetic Bead Processing
11 Jan 24
A method may be implemented for in-tip flow-through magnetic bead processing.
Gianluca Artioli, Brian Mather, Dave Jones
Filed: 30 Jun 23
Utility
Fanout Flow Cell
11 Jan 24
Provided herein include various examples of a flow cell and methods for forming aspects of flow cell.
Ravi BILLA, John WALKER, Arvin EMADI, Jon ADAY, Tara BOZORG-GRAYELI, Ludovic VINCENT, Hai TRAN, Sanket RATHORE
Filed: 1 Feb 22
Utility
Compositions and Methods for Capturing and Amplifying Target Polynucleotides Using Modified Capture Primers
11 Jan 24
A composition for capturing target polynucleotides at a surface of a substrate is provided.
Hayden Black, Esteban Armijo, Mathieu Lessard-Viger
Filed: 20 Dec 21
Utility
Methods and Systems for Generation and Error-correction of Unique Molecular Index Sets with Heterogeneous Molecular Lengths
11 Jan 24
The disclosed embodiments concern methods, apparatus, systems and computer program products for determining sequences of interest using unique molecular index sequences that are uniquely associable with individual polynucleotide fragments, including sequences with low allele frequencies and long sequence length.
Kevin Wu, Chen Zhao, Han-Yu Chuang, Alex So, Stephen Tanner, Stephen M. Gross
Filed: 3 Aug 23
Utility
Splicing Site Classification Using Neural Networks
11 Jan 24
The technology disclosed relates to splice site prediction and aberrant splicing detection.
Kishore Jaganathan, Kai-how Farh, Jeremy F. McRAE, Sofia Kyriazopoulou Panagiotopoulou
Filed: 26 Jul 22
Utility
Hybrid Nanopore Sensors
11 Jan 24
The disclosure provides detection apparatus having one or more nanopores, methods for making apparatus having one or more nanopore and methods for using apparatus having one or more nanopores.
BOYAN BOYANOV, JEFFREY G MANDELL, KEVIN L GUNDERSON, JINGWEI BAI, LIANGLIANG QIANG, BRADLEY BAAS
Filed: 29 Jun 23
Utility
Sensor System
11 Jan 24
A system includes an image sensor structure and a flow cell.
Tracy Helen FUNG, Hai Quang TRAN
Filed: 20 Sep 23
Utility
Methods and Systems for Analyzing Nucleic Acid Sequences
11 Jan 24
Methods of identifying changes in genomic DNA copy number are disclosed.
Srinka GHOSH
Filed: 23 Jun 23
Utility
Methods of Analyzing Nucleic Acids
4 Jan 24
Presented herein are methods and compositions for analyzing rare nucleic acid species.
Scott Kuersten, Agnes Radek, Ramesh Vaidyanathan, Haiying Li Grunenwald
Filed: 6 Sep 23
Utility
Systems and Methods Including a Rotary Valve for at Least One of Sample Preparation or Sample Analysis
4 Jan 24
Systems and methods for conducting designated reactions that include a fluidic network having a sample channel, a reaction chamber, and a reservoir.
Sebastian Bohm, Alex Aravanis, Alexander Hsiao, Behnam Javanmardi, Tarun Kumar Khurana, Hai Quang Tran, Majid Aghababazadeh, M. Shane Bowen, Boyan Boyanov, Dale Buermann
Filed: 18 Sep 23
Utility
Hydration and Homogenization of Lyophilized Reagents
4 Jan 24
Provided are systems and methods including, under control of control circuitry implementing a hydration and homogenization protocol, hydrating lyophilized reagents and homogenizing the hydrated reagents.
Bradley DREWS, Mahmood GHANBARI MARDASI
Filed: 29 Jun 23
Utility
Platform for Discovery and Analysis of Therapeutic Agents
4 Jan 24
A method of characterizing candidate agents including steps of (a) providing a library of candidate agents attached to nucleic acid tags; (b) contacting the library with a solid support to attach the candidate agents to the solid support, whereby an array of candidate agents is formed; (c) contacting the array with a screening agent, wherein one or more candidate agents in the array react with the screening agent; (d) detecting the array to determine that at least one candidate agent in the array reacts with the screening agent; (e) sequencing the nucleic acid tag to determine the tag sequences attached to candidate agents in the array; and (f) identifying the at least one candidate agent in the array that reacts with the screening agent based on the tag sequence that is attached to the at least one candidate agent.
Molly He, Michael Previte, Misha Golynskiy, Matthew William Kellinger, Sergio Peisajovich, Jonathan Mark Boutell
Filed: 14 Sep 23
Utility
Non-contact Dispensers and Related Systems and Methods
4 Jan 24
Non-contact dispensers and related systems and methods are disclosed.
Bryan Crane
Filed: 28 Jun 23
Utility
Light Detection Devices with Protective Liner and Methods Related to Same
28 Dec 23
Light detection devices and related methods are provided.
Xiuyu CAI, Joseph Francis PINTO, Thomas A. BAKER, Tracy Helen FUNG
Filed: 11 Sep 23
Utility
Enhancing Clustering Efficiency and Kinetics
28 Dec 23
A co-polymer includes a plurality of a first monomer including a terminal functional group that is to attach to at least two different primers; a plurality of a second monomer including a second functional group that is different from the terminal functional group, and that is selected from the group consisting of a phenyl group, methoxy propyl, glycosyl, vinyl pyrrolidone, and an imidazole group; and a plurality of a third monomer that is different from the first and second monomers.
Gianluca Andrea Artioli, Timothy J.N. Beech, Mathieu Lessard-Viger, Rebecca Turk-MacLeod, Brian D. Mather, Weixian Xi, Xavier von Hatten
Filed: 6 Jun 23
Utility
Variant Calling of High Coverage Samples with a Restricted Memory
28 Dec 23
Systems, methods, and apparatus are described herein for identifying callable regions and performing variant calling while operating within allocated memory.
Adam Michael Birnbaum, Fabian Jobst Klötzl, Arun Visvanath
Filed: 23 Jun 23
Utility
Methods and Compositions for Addressing Inefficiencies In Amplification Reactions
28 Dec 23
Methods and systems for decreasing amplification bias and primer-dimer formation in amplification reactions and for amplifying a plurality of target polynucleotides from a sample in a single reaction and for sequencing the target polynucleotides where samples can include forensic samples and where target polynucleotides can include identity- or ancestry-informative markers, short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs).
Jon-Matthew Belton, Johann Felix Schlesinger, Siarhei Manakou, Amanda Garfinkel Young
Filed: 1 Jun 23
Utility
Substrates for Performing Quantification Processes and Related Systems and Methods
28 Dec 23
Substrates for performing quantification processes and related systems and methods are disclosed.
Bryan Crane
Filed: 27 Jun 23