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Exact Sciences (EXAS)

Utility
Nucleic Acid Control Molecules from Non-human Organisms
5 May 22
The present invention provides synthetic DNA strands that find use as process controls in DNA processing and nucleic acid testing methods.
Hatim T. Allawi, Graham P. Lidgard, Brian Aizenstein, Melissa M. Gray
Filed: 18 Nov 21
Utility
Compositions and Methods for Performing Methylation Detection Assays
10 Feb 22
Provided herein is technology relating to performing methylation assays.
David Alan Ahlquist, William Russell Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi, Abram Michael Vaccaro
Filed: 23 Aug 21
Utility
Mutation Detection Assay
30 Dec 21
A method of sample analysis is provided.
Hongzhi Zou, Graham P. Lidgard, Michael J. Domanico, Hatim Allawi
Filed: 8 Jul 21
Utility
Nucleic acid control molecules from non-human organisms
28 Dec 21
The present invention provides synthetic DNA strands that find use as process controls in DNA processing and nucleic acid testing methods.
Hatim T. Allawi, Graham P. Lidgard, Brian Aizenstein, Melissa M. Gray
Filed: 19 Jul 17
Utility
Detecting Esophageal Disorders
9 Dec 21
Provided herein is technology for esophageal disorder screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of esophageal disorders (e.g., Barrett's esophagus, Barrett's esophageal dysplasia, etc.).
David A. Ahlquist, William R. Taylor, John B. Kisiel, Douglas W. Mahoney, Tracy C. Yab, Graham P. Lidgard, Hatim T. Allawi
Filed: 24 Aug 21
Utility
Multiplex amplification detection assay II
7 Dec 21
Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA.
Hatim T. Allawi, William G. Weisburg, Graham P. Lidgard, Michael W. Kaiser, Abram M. Vaccaro, Gracie Shea
Filed: 12 Feb 20
Utility
Detecting Colorectal Neoplasm
11 Nov 21
Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.
David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
Filed: 16 Jul 21
Utility
Methods for detecting epigenetic modifications
19 Oct 21
A method of detecting a predisposition to, or the incidence of, cancer in a sample comprises detecting an epigenetic change in at least one gene selected from an NDRG4/NDRG2 subfamily gene, GATA4, OSMR, GATA5, SFRP1, ADAM23, JPH3, SFRP2, APC, MGMT, TFPI2, BNIP3, FOXE1, SYNE1, SOX17, PHACTR3 and JAM3, wherein detection of the epigenetic change is indicative of a predisposition to, or the incidence of, cancer.
Manon Van Engeland, Manon Adriaan De Bruine, Arjan Griffioen, Joost Louwagie, Katja Bierau, Gontran Brichard, Gaetan Otto, Maarten Penning
Filed: 8 Oct 18
Utility
Detection of colon neoplasia by analysis of methylated DNA
14 Sep 21
Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer, in particular, colorectal cancer.
Hatim T. Allawi, Michael W. Kaiser, Graham P. Lidgard, William R. Taylor, Tamara J. Sander, Abram M. Vaccaro
Filed: 26 Jan 18
Utility
Compositions and methods for performing methylation detection assays
14 Sep 21
Provided herein is technology relating to performing methylation assays.
David Alan Ahlquist, William Russell Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi, Abram Michael Vaccaro
Filed: 20 Jun 18
Utility
Detecting esophageal disorders
31 Aug 21
Provided herein is technology for esophageal disorder screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of esophageal disorders (e.g., Barrett's esophagus, Barrett's esophageal dysplasia, etc.).
David A. Ahlquist, William R. Taylor, John B. Kisiel, Douglas W. Mahoney, Tracy C. Yab, Graham P. Lidgard, Hatim T. Allawi
Filed: 13 Sep 19
Utility
Detection and Analysis of Methylated Dna
26 Aug 21
Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
Hatim Allawi, Graham P. Lidgard, Maria Giakoumopoulos, David A. Ahlquist, William R. Taylor, Douglas Mahoney
Filed: 7 May 21
Utility
Mutation detection assay
17 Aug 21
A method of sample analysis is provided.
Hongzhi Zou, Graham P. Lidgard, Michael J. Domanico, Hatim Allawi
Filed: 12 Sep 19
Utility
Sample Collection Device
12 Aug 21
Provided herein is technology relating to collecting and preparing samples.
Graham P. Lidgard, Michael J. Domanico, Keith Fourrier, James P. Light, II, Scott Castanon, Keith Kopitzke
Filed: 28 Apr 21
Utility
Detecting colorectal neoplasm
3 Aug 21
Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.
David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
Filed: 26 Mar 15
Utility
Methylation Assay
22 Jul 21
A method for detecting a methylated genomic locus is provided.
Graham P. Lidgard, Michael J. Domanico, Hatim Allawi, Hongzhi Zou
Filed: 8 Feb 21
Utility
Detecting Breast Cancer
8 Jul 21
Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.
David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Tracy C. Yab, John B. Kisiel, Hatim T. Allawi, Graham P. Lidgard, Michael W. Kaiser
Filed: 18 Mar 21
Utility
Normalization of Polymerase Activity
24 Jun 21
Provided herein is technology relating to the amplification-based detection of nucleic acids and particularly, but not exclusively, to methods and compositions for minimizing variability in the activity between different samples or manufacturing lots of DNA polymerases, such as Taq DNA polymerase.
Hatim Allawi, Rebecca Oldham-Haltom, Zubin Gagrat, Michael Domanico, Graham Lidgard
Filed: 11 Feb 21
Utility
Synthetic Nucleic Acid Control Molecules
10 Jun 21
The present invention provides synthetic DNA strands that find use as controls or in nucleic acid testing methods.
Ilse A. Tyler, Keith Yaeger, Michael J. Domanico, Hatim Allawi, Graham P. Lidgard
Filed: 3 Dec 20
Utility
Detecting Breast Cancer
10 Jun 21
Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.
David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Tracy C. Yab, John B. Kisiel, Hatim T. Allawi, Graham P. Lidgard, Michael W. Kaiser
Filed: 17 Feb 21
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