47 patents
Page 2 of 3
Utility
Detection of colon neoplasia by analysis of methylated DNA
14 Sep 21
Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer, in particular, colorectal cancer.
Hatim T. Allawi, Michael W. Kaiser, Graham P. Lidgard, William R. Taylor, Tamara J. Sander, Abram M. Vaccaro
Filed: 26 Jan 18
Utility
Compositions and methods for performing methylation detection assays
14 Sep 21
Provided herein is technology relating to performing methylation assays.
David Alan Ahlquist, William Russell Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi, Abram Michael Vaccaro
Filed: 20 Jun 18
Utility
Detecting esophageal disorders
31 Aug 21
Provided herein is technology for esophageal disorder screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of esophageal disorders (e.g., Barrett's esophagus, Barrett's esophageal dysplasia, etc.).
David A. Ahlquist, William R. Taylor, John B. Kisiel, Douglas W. Mahoney, Tracy C. Yab, Graham P. Lidgard, Hatim T. Allawi
Filed: 13 Sep 19
Utility
Mutation detection assay
17 Aug 21
A method of sample analysis is provided.
Hongzhi Zou, Graham P. Lidgard, Michael J. Domanico, Hatim Allawi
Filed: 12 Sep 19
Utility
Detecting colorectal neoplasm
3 Aug 21
Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.
David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
Filed: 26 Mar 15
Utility
Detection of neoplasia by analysis of methylated dna
8 Jun 21
Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
Hatim Allawi, Graham P. Lidgard, Maria Giakoumopoulos, David A. Ahlquist, William R. Taylor, Douglas Mahoney
Filed: 2 Jul 19
Utility
Sample collection device
1 Jun 21
Provided herein is technology relating to collecting and preparing samples.
Graham P. Lidgard, Michael J. Domanico, Keith Fourrier, James P. Light, II, Scott Castanon, Keith Kopitzke
Filed: 29 May 20
Utility
Detecting breast cancer
13 Apr 21
Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.
David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Tracy C. Yab, John B. Kisiel, Hatim T. Allawi, Graham P. Lidgard, Michael W. Kaiser
Filed: 28 Nov 18
Utility
Normalization of polymerase activity
23 Mar 21
Provided herein is technology relating to the amplification-based detection of nucleic acids and particularly, but not exclusively, to methods and compositions for minimizing variability in the activity between different samples or manufacturing lots of DNA polymerases, such as Taq DNA polymerase.
Hatim Allawi, Rebecca Oldham-Haltom, Zubin Gagrat, Michael Domanico, Graham Lidgard
Filed: 18 Sep 18
Utility
Detecting breast cancer
2 Mar 21
Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.
David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Tracy C. Yab, John B. Kisiel, Hatim T. Allawi, Graham P. Lidgard, Michael W. Kaiser
Filed: 28 Nov 18
Utility
Detecting prostate cancer
2 Mar 21
Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.
David A. Ahlquist, William R. Taylor, John B. Kisiel, Tracy C. Yab, Douglas W. Mahoney, Brian A. Dukek, Matthew T. Gettman, Hatim T. Allawi
Filed: 27 Feb 18
Utility
Ergonomic stool specimen container and enclosing holder systems, methods, and kits
19 Jan 21
Provided herein is technology relating to collecting and containing samples and particularly, but not exclusively, to technology for collecting and containing a stool specimen.
Joseph E. Schiestle, Krystal A. Burger, Timothy A. Parmer, Jad A. Lunde, Sam M. Jang, David A. Schuelke, David B. Wolgemuth, Jing Yang Lu
Filed: 14 Feb 19
Utility
Synthetic nucleic acid control molecules
12 Jan 21
The present invention provides synthetic DNA strands that find use as controls or in nucleic acid testing methods.
Ilse A. Tyler, Keith Yaeger, Michael J. Domanico, Hatim Allawi, Graham P. Lidgard
Filed: 23 Oct 18
Utility
Detecting colorectal neoplasm
4 Jan 21
Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.
David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
Filed: 8 Jan 20
Utility
Digital sequence analysis of DNA methylation
21 Dec 20
The present invention relates to methods and compositions for determination of and uses of specific methylation patterns indicative of adenoma and carcinoma.
David A. Ahlquist, William R. Taylor, Hongzhi Zou, Graham P. Lidgard
Filed: 27 Oct 19
Utility
Isolation and detection of DNA from plasma
2 Nov 20
Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA.
Hatim Allawi, Graham P. Lidgard, Brian Aizenstein, Tamara J. Sander, Maria Giakoumopoulos, Michael W. Kaiser, Melissa M. Gray, Abram Michael Vaccaro
Filed: 25 Oct 16
Utility
Isolation of nucleic acids
2 Nov 20
Provided herein is technology relating to isolating nucleic acids.
Janelle J. Bruinsma, Michael J. Domanico, Graham P. Lidgard, Hongzhi Zou, William G. Weisburg, Hemanth D. Shenoi, James P. Light, II, Keith Kopitzke, John Zeis
Filed: 5 Dec 18
Utility
Methods for detecting epigenetic modifications
19 Oct 20
A method of detecting a predisposition to, or the incidence of, cancer in a sample comprises detecting an epigenetic change in at least one gene selected from an NDRG4/NDRG2 subfamily gene, GATA4, OSMR, GATA5, SFRP1, ADAM23, JPH3, SFRP2, APC, MGMT, TFPI2, BNIP3, FOXE1, SYNE1, SOX17, PHACTR3 and JAM3, wherein detection of the epigenetic change is indicative of a predisposition to, or the incidence of, cancer.
Manon Van Engeland, Manon Adriaan De Bruine, Arjan Griffioen, Joost Louwagie, Katja Bierau, Gontran Brichard, Gaetan Otto, Maarten Penning
Filed: 3 May 18
Utility
Sample collection device
6 Jul 20
Provided herein is technology relating to collecting and preparing samples.
Graham P. Lidgard, Michael J. Domanico, Keith Fourrier, James P. Light, II, Scott Castanon, Keith Kopitzke
Filed: 7 Aug 17
Utility
Modification of DNA on magnetic beads
6 Jul 20
Provided herein is technology related to the chemical modification and purification of DNA.
Michael J. Domanico, Hatim Allawi, Graham P. Lidgard, Brian Aizenstein, Oliver Hunt, Tobias Charles Zutz
Filed: 17 Oct 18