23 patents
Utility
DNA Methylation and Mutational Analysis Methods for Bladder Cancer Surveillance
23 Nov 23
The present disclosure relates to methods of monitoring bladder cancer patients and analyzing patient samples for presence of methylated DNA and optionally particular gene mutations.
Margarita LOPATIN, Athanasios TSIATIS, Christopher N. SILK, David P. MILLER, Michael R. CRAGER, Phillip FEBBO, Dejan KNEZEVIC
Filed: 4 Apr 23
Utility
Systems and methods for pre-analytical substrate processing
7 Nov 23
Some embodiments presented in this disclosure concern an Automated Tissue Dissection (ATD) System.
Hubert Yeung, Amy Lee Hsieh Yuan, Chun Wai Lee, Gabriel Jesus Samuel Perlas Moraleda, Jonathan M. Cassel
Filed: 21 Jun 19
Utility
Method to use gene expression to determine likelihood of clinical outcome of renal cancer
3 Oct 23
The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
Wayne Cowens, Steven Shak, Audrey Goddard, Dejan Knezevic, Joffre Baker, Michael C. Kiefer, Tara Maddala, Frederick L. Baehner
Filed: 19 Nov 20
Utility
DNA methylation and mutational analysis methods for bladder cancer surveillance
16 May 23
The present disclosure relates to methods of monitoring bladder cancer patients and analyzing patient samples for presence of methylated DNA and optionally particular gene mutations.
Margarita Lopatin, Athanasios Tsiatis, Christopher N. Silk, David P. Miller, Michael Crager, Phillip Febbo, Dejan Knezevic
Filed: 17 May 18
Utility
Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer
10 Jan 23
The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient.
Steven Shak, George Andrew Watson, Michael R. Crager, Tara Maddala, Margarita Lopatin, Audrey Goddard, Dejan Knezevic, Christer Svedman
Filed: 2 Nov 20
Utility
CorrectedMethod to Use Gene Expression to Determine Likelihood of Clinical Outcome of Renal Cancer
17 Feb 22
The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
Wayne COWENS, Steven SHAK, Audrey GODDARD, Dejan KNEZEVIC, Joffre BAKER, Michael C. KIEFER, Tara MADDALA, Frederick L. BAEHNER
Filed: 19 Nov 20
Utility
CorrectedGene Expression Profile Algorithm for Calculating a Recurrence Score for a Patient with Kidney Cancer
10 Feb 22
The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient.
Steven SHAK, George Andrew WATSON, Michael R. CRAGER, Tara MADDALA, Margarita LOPATIN, Audrey GODDARD, Dejan KNEZEVIC, Christer SVEDMAN
Filed: 2 Nov 20
Utility
Gene expression markers for breast cancer prognosis
11 Jan 22
The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
Melody A. Cobleigh, Steven Shak, Joffre B. Baker, Maureen T. Cronin
Filed: 15 Feb 18
Utility
Methods for depleting RNA from nucleic acid samples
19 Oct 21
The invention relates to methods of depleting RNA from a nucleic acid sample.
Dominick Sinicropi, John Morlan
Filed: 10 Jan 18
Utility
Method to Use Gene Expression to Determine Likelihood of Clinical Outcome of Renal Cancer
3 Jun 21
The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
Wayne COWENS, Steven SHAK, Audrey GODDARD, Dejan KNEZEVIC, Joffre BAKER, Michael C. KIEFER, Tara MADDALA, Frederick L. BAEHNER
Filed: 19 Nov 20
Utility
Gene Expression Profile Algorithm for Calculating a Recurrence Score for a Patient with Kidney Cancer
20 May 21
The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient.
Steven SHAK, George Andrew WATSON, Michael R. CRAGER, Tara MADDALA, Margarita LOPATIN, Audrey GODDARD, Dejan KNEZEVIC, Christer SVEDMAN
Filed: 2 Nov 20
Utility
Gene expression profile algorithm and test for determining prognosis of prostate cancer
18 May 21
The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes, or their co-expressed genes, from a biological sample obtained from a prostate cancer patient.
Steven Shak, Mark Lee, William F. Novotny, Tara Maddala, Michael R. Crager, Diana Cherbavaz, Robert J. Pelham, Carl L. Millward, Dejan Knezevic
Filed: 2 May 17
Utility
Methods to Predict Clinical Outcome of Cancer
4 Mar 21
The present invention provides methods to determine the prognosis and appropriate treatment for patients diagnosed with cancer, based on the expression levels of one or more biomarkers.
Joffre B. BAKER, Maureen T. CRONIN, Francois COLLIN, Mei-Lan LIU
Filed: 11 Sep 20
Utility
Method to use gene expression to determine likelihood of clinical outcome of renal cancer
12 Jan 21
The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
Wayne Cowens, Steven Shak, Audrey Goddard, Dejan Knezevic, Joffre Baker, Michael C. Kiefer, Tara Maddala, Frederick L. Baehner
Filed: 5 Dec 16
Utility
Prediction of Likelihood of Cancer Recurrence
23 Sep 20
The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of cancer, in particular of breast cancer.
Joffre B. Baker, John L. Bryant, Soonmyung Paik, Steven Shak
Filed: 2 Mar 20
Utility
Method of Predicting Breast Cancer Prognosis
19 Aug 20
The present invention relates to biomarkers associated with breast cancer prognosis.
Joffre B. BAKER, Dominick SINICROPI, Robert J. PELHAM, Michael R. CRAGER, Francois COLLIN, James C. STEPHANS, Mei-Lan LIU, John D. MORLAN, Kunbin QU
Filed: 6 Feb 20
Utility
Method for Using Gene Expression to Determine Prognosis of Prostate Cancer
12 Aug 20
Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for said patient, and likelihood that said patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status, are provided herein.
Steven SHAK, Frederick L. BAEHNER, Tara MADDALA, Mark LEE, Robert J. PELHAM, Wayne COWENS, Diana CHERBAVAZ, Michael C. KIEFER, Michael CRAGER, Audrey GODDARD, Joffre B. BAKER
Filed: 24 Feb 20
Utility
DNA Methylation and Mutational Analysis Methods for Bladder Cancer Surveillance
27 May 20
The present disclosure relates to methods of monitoring bladder cancer patients and analyzing patient samples for presence of methylated DNA and optionally particular gene mutations.
Margarita LOPATIN, Athanasios TSIATIS, Christopher N. SILK, David P. Miller, Michael CRAGER, Phillip FEBBO, Dejan KNEZEVIC
Filed: 16 May 18
Utility
Prediction of likelihood of cancer recurrence
13 Apr 20
The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of cancer, in particular of breast cancer.
Joffre B. Baker, John L. Bryant, Soonmyung Paik, Steven Shak
Filed: 10 Aug 17
Utility
Methods of Incorporation of Transcript Chromosomal Locus Information for Identification of Biomarkers of Disease Recurrence Risk
1 Apr 20
The present invention provides methods for incorporating transcript chromosomal locus information for identification of biomarkers of disease recurrence risk.
Michael C. Kiefer, Francois Collin, Samuel Levy, Joffre B. Baker, Michael R. Crager, Mark R. Segal
Filed: 26 Sep 19