14 patents
Utility
DNA Methylation and Mutational Analysis Methods for Bladder Cancer Surveillance
23 Nov 23
The present disclosure relates to methods of monitoring bladder cancer patients and analyzing patient samples for presence of methylated DNA and optionally particular gene mutations.
Margarita LOPATIN, Athanasios TSIATIS, Christopher N. SILK, David P. MILLER, Michael R. CRAGER, Phillip FEBBO, Dejan KNEZEVIC
Filed: 4 Apr 23
Utility
CorrectedMethod to Use Gene Expression to Determine Likelihood of Clinical Outcome of Renal Cancer
17 Feb 22
The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
Wayne COWENS, Steven SHAK, Audrey GODDARD, Dejan KNEZEVIC, Joffre BAKER, Michael C. KIEFER, Tara MADDALA, Frederick L. BAEHNER
Filed: 19 Nov 20
Utility
CorrectedGene Expression Profile Algorithm for Calculating a Recurrence Score for a Patient with Kidney Cancer
10 Feb 22
The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient.
Steven SHAK, George Andrew WATSON, Michael R. CRAGER, Tara MADDALA, Margarita LOPATIN, Audrey GODDARD, Dejan KNEZEVIC, Christer SVEDMAN
Filed: 2 Nov 20
Utility
Method to Use Gene Expression to Determine Likelihood of Clinical Outcome of Renal Cancer
3 Jun 21
The present disclosure provides gene and gene sets, the expression of which is important in the classification and/or prognosis of cancer, in particular of renal cell carcinoma.
Wayne COWENS, Steven SHAK, Audrey GODDARD, Dejan KNEZEVIC, Joffre BAKER, Michael C. KIEFER, Tara MADDALA, Frederick L. BAEHNER
Filed: 19 Nov 20
Utility
Gene Expression Profile Algorithm for Calculating a Recurrence Score for a Patient with Kidney Cancer
20 May 21
The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient.
Steven SHAK, George Andrew WATSON, Michael R. CRAGER, Tara MADDALA, Margarita LOPATIN, Audrey GODDARD, Dejan KNEZEVIC, Christer SVEDMAN
Filed: 2 Nov 20
Utility
Methods to Predict Clinical Outcome of Cancer
4 Mar 21
The present invention provides methods to determine the prognosis and appropriate treatment for patients diagnosed with cancer, based on the expression levels of one or more biomarkers.
Joffre B. BAKER, Maureen T. CRONIN, Francois COLLIN, Mei-Lan LIU
Filed: 11 Sep 20
Utility
Prediction of Likelihood of Cancer Recurrence
23 Sep 20
The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of cancer, in particular of breast cancer.
Joffre B. Baker, John L. Bryant, Soonmyung Paik, Steven Shak
Filed: 2 Mar 20
Utility
Method of Predicting Breast Cancer Prognosis
19 Aug 20
The present invention relates to biomarkers associated with breast cancer prognosis.
Joffre B. BAKER, Dominick SINICROPI, Robert J. PELHAM, Michael R. CRAGER, Francois COLLIN, James C. STEPHANS, Mei-Lan LIU, John D. MORLAN, Kunbin QU
Filed: 6 Feb 20
Utility
Method for Using Gene Expression to Determine Prognosis of Prostate Cancer
12 Aug 20
Molecular assays that involve measurement of expression levels of prognostic biomarkers, or co-expressed biomarkers, from a biological sample obtained from a prostate cancer patient, and analysis of the measured expression levels to provide information concerning the likely prognosis for said patient, and likelihood that said patient will have a recurrence of prostate cancer, or to classify the tumor by likelihood of clinical outcome or TMPRSS2 fusion status, are provided herein.
Steven SHAK, Frederick L. BAEHNER, Tara MADDALA, Mark LEE, Robert J. PELHAM, Wayne COWENS, Diana CHERBAVAZ, Michael C. KIEFER, Michael CRAGER, Audrey GODDARD, Joffre B. BAKER
Filed: 24 Feb 20
Utility
DNA Methylation and Mutational Analysis Methods for Bladder Cancer Surveillance
27 May 20
The present disclosure relates to methods of monitoring bladder cancer patients and analyzing patient samples for presence of methylated DNA and optionally particular gene mutations.
Margarita LOPATIN, Athanasios TSIATIS, Christopher N. SILK, David P. Miller, Michael CRAGER, Phillip FEBBO, Dejan KNEZEVIC
Filed: 16 May 18
Utility
Methods of Incorporation of Transcript Chromosomal Locus Information for Identification of Biomarkers of Disease Recurrence Risk
1 Apr 20
The present invention provides methods for incorporating transcript chromosomal locus information for identification of biomarkers of disease recurrence risk.
Michael C. Kiefer, Francois Collin, Samuel Levy, Joffre B. Baker, Michael R. Crager, Mark R. Segal
Filed: 26 Sep 19
Utility
Algorithms and Methods for Assessing Late Clinical Endpoints in Prostate Cancer
5 Feb 20
The present disclosure relates to uses of a multiple gene-expression based Genomic Prostate Score™ (GPS™) algorithm for assessment of various clinical endpoints in prostate cancer patients, such as risks of clinical recurrence (CR), biochemical recurrence (BCR), distant metastasis (Mets), and prostate cancer death (PCD).
Ruixiao LU, Michael CRAGER, Nan ZHANG, Tara MADDALA, Phillip FEBBO, Hugh Jeffrey LAWRENCE
Filed: 11 Feb 18
Utility
Systems and Methods for Pre-analytical Substrate Processing
25 Dec 19
Some embodiments presented in this disclosure concern an Automated Tissue Dissection (ATD) System.
Hubert Yeung, Amy Lee Hsieh Yuan, Chun Wai Lee, Gabriel Jesus Samuel Perlas Moraleda, Jonathan M. Cassel
Filed: 20 Jun 19
Utility
Automated Sample Preparation System and Applications Thereof
25 Dec 19
A system for automation of sample preparation is disclosed.
Hubert Yeung, Amy Lee Hsieh Yuan, Chun Wai Lee, Gabriel Jesus Samuel Perlas Moraleda
Filed: 20 Jun 19
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