178 patents
Page 7 of 9
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Microbial Production of Fatty Diols
11 Mar 21
The disclosure relates to fatty diols and recombinant microorganisms for producing them.
Andreas W. Schirmer, Noah HELMAN, Haibo Wang, Zhihao Hu, Vikranth Arlagadda, Alma Itzel RAMOS-SOLIS, Elizabeth Clarke
Filed: 1 Jun 20
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Methods of Producing Omega-hydroxylated Fatty Acid Derivatives
11 Mar 21
The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them.
Andreas W. Schirmer, Haibo Wang, Stephen B. Del Cardayre, Zhihao Hu, Louis G. Hom, Baolong Zhu, Cindy Chang, Emanuela E. Popova
Filed: 29 Jun 20
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Vinylisomerase-dehydratases, alkenol dehydratases, linalool dehydratases and crotyl alcohol dehydratases and methods for making and using them
9 Mar 21
In alternative embodiments, provided are non-natural or genetically engineered vinylisomerase-dehydratase enzymes, including alkenol dehydratases, linalool dehydratases and crotyl alcohol dehydratases.
Stephanie J. Culler, Robert J. Haselbeck, Harish Nagarajan, Iuri Estrada Gouvea, Daniel Johannes Koch, Mateus Schreiner Garcez Lopes, Lucas Pedersen Parizzi
Filed: 26 May 16
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Microorganisms for the Production of Methacrylic Acid
11 Feb 21
The invention provides a non-naturally occurring microbial organism having a 2-hydroxyisobutyric acid, 3-hydroxyisobutyric acid or methacrylic acid pathway.
Anthony P. Burgard, Mark J. Burk, Robin E. Osterhout, Priti Pharkya
Filed: 19 Aug 20
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Methods and Compositions for Producing Hydrocarbons
11 Feb 21
Compositions and methods for producing aldehydes, alkanes, and alkenes are described herein.
Andreas W. Schirmer, Mathew A. Rude, Shane A. BRUBAKER
Filed: 7 Jan 20
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Recombinant microorganisms for the production of fatty amines
26 Jan 21
The disclosure relates to recombinant microorganisms for the production of fatty amines and derivatives thereof.
Stephen B. Del Cardayre, Louis G. Hom
Filed: 5 Dec 14
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Enzyme variants with improved ester synthase properties
19 Jan 21
The disclosure relates to enzyme variants with improved ester synthase properties for the production of fatty acid esters.
Andrew M. Shumaker, Bernardo M. da Costa, Kevin Holden, Louis G. Hom, Tarah S. Baron, Noah Helman
Filed: 18 Jan 18
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Acetyl-coa Carboxylase Variants
14 Jan 21
The disclosure relates to acetyl-CoA carboxylase (ACC) variants and host cells expressing them for the production of malonyl-CoA derived compounds including fatty acid derivatives.
Derek L. GREENFIELD, Donald E. TRIMBUR, Andreas W. SCHIRMER, Cindy CHANG, Behnaz BEHROUZIAN, Jessica WINGER
Filed: 26 Feb 20
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Process of Separating Components of a Fermentation Broth
6 Jan 21
A process of isolating 1,4-butanediol (1,4-BDO) from a fermentation broth includes separating a liquid fraction enriched in 1,4-BDO from a solid fraction comprising cells, removing water from said liquid fraction, removing salts from said liquid fraction, and purifying 1,4-BDO.
Warren Clark, Michael Japs, Mark J. Burk
Filed: 13 Apr 20
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Process and Systems for Obtaining 1,4-BUTANEDIOL from Fermentation Broths
6 Jan 21
A process of purifying 1,4-butanediol (1,4-BDO) from a fermentation broth including separating solid materials, salts and water, and subjecting the resulting material to a two, three or four column distillation system, that can include a wiped film evaporator to produce a purified 1,4-butanediol.
SVB Janardhan Garikipati, Michael Japs, Ishmael M. Sonico
Filed: 23 Feb 20
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Microorganisms for Producing 4C-5C Compounds with Unsaturation and Methods Related Thereto
6 Jan 21
The invention provides a non-naturally occurring microbial organism having a butadiene, crotyl alcohol, 2,4-pentadienoate, 3-buten-2-ol, or 3-buten-1-ol, pathway.
Stephanie J. Culler, Mark J. Burk, Robin E. Osterhout, Priti Pharkya
Filed: 28 May 20
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1,3-FATTY Diol Compounds and Derivatives Thereof
9 Dec 20
The disclosure relates to the field of specialty chemicals.
Haibo WANG
Filed: 9 Jan 20
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Microorganisms and Methods for Producing 2,4-PENTADIENOATE, Butadiene, Propylene, 1,3-BUTANEDIOL and Related Alcohols
9 Dec 20
The invention provides non-naturally occurring microbial organisms containing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol, crotyl alcohol or 3-buten-1-ol pathways comprising at least one exogenous nucleic acid encoding a butadiene pathway enzyme expressed in a sufficient amount to produce 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol, crotyl alcohol or 3-buten-1-ol.
Robin E. Osterhout, Anthony P. Burgard, Mark J. Burk
Filed: 12 Jan 20
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Methods and Organisms for Utilizing Synthesis Gas or Other Gaseous Carbon Sources and Methanol
9 Dec 20
The invention provides a non-naturally occurring microbial organism having an acetyl-CoA pathway and the capability of utilizing syngas or syngas and methanol.
Mark J. Burk, Christophe H. Schilling, Anthony P. Burgard, John D. Trawick
Filed: 2 Feb 20
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Omega-hydroxylase-related Fusion Polypeptides with Improved Properties
25 Nov 20
The disclosure relates to omega-hydroxylase-related fusion polypeptides that result in improved omega-hydroxylated fatty acid derivative production when expressed in recombinant host cells.
Baolong ZHU, Andreas W. Schirmer, Cindy CHANG
Filed: 22 Oct 19
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Engineered microorgansims and methods for improved crotyl alcohol production
23 Nov 20
Disclosed are methods and engineered microorganisms that enhance or improve the production of crotyl alcohol.
Stephanie J. Culler, Nicholas Eakley, Kevin Gregory Hoff, Robin E. Osterhout, Priti Pharkya, Erik C. Ralph, Stephen Van Dien
Filed: 6 Apr 16
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Production of fatty acids and derivatives thereof
23 Nov 20
Compositions and methods for production of fatty alcohols using recombinant microorganisms are provided as well as fatty alcohol compositions produced by such methods.
Jay D. Keasling, Zhihao Hu, Chris Somerville, George Church, David Berry, Lisa C. Friedman, Andreas Schirmer, Shane Brubaker, Stephen B. Del Cardayre
Filed: 6 Mar 17
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Alcohol Dehydrogenase Variants
11 Nov 20
Described herein are non-natural NAD+-dependent alcohol dehydrogenases (ADHs) capable of at least two fold greater conversion of methanol or ethanol to formaldehyde or acetaldehyde, respectively, as compared to its unmodified counterpart.
Stefan Andrae, Michael Patrick Kuchinskas, Jingyi Li, Harish Nagarajan, Priti Pharkya
Filed: 16 Feb 20
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Microorganisms and Methods for the Production of Butadiene Using Acetyl-coa
11 Nov 20
The invention provides non-naturally occurring microbial organisms containing butadiene or 2,4-pentadienoate pathways comprising at least one exogenous nucleic acid encoding a butadiene or 2,4-pentadienoate pathway enzyme expressed in a sufficient amount to produce butadiene or 2,4-pentadienoate.
Priti Pharkya, Anthony P. Burgard, Mark J. Burk
Filed: 24 Oct 19
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Microorganisms and Processes for Producing Terephthalic Acid and Its Salts
21 Oct 20
The invention provides non-naturally occurring microbial organisms having a (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate (2H3M4OP) pathway, p-toluate pathway, and/or terephthalate pathway.
Robin E. Osterhout, Anthony P. Burgard, Mark J. Burk
Filed: 3 May 20