40 patents
Page 2 of 2
Utility
High Speed Modulation Sample Imaging Apparatus and Method
28 Oct 21
This disclosure relates to systems and methods for high speed modulation sample imaging.
DAAF SANDKUIJL, Alexander V. Loboda, ADAM CAREW, MINALINI LAKSHMAN
Filed: 10 Sep 19
Utility
Multi-primer Amplification Method for Barcoding of Target Nucleic Acids
21 Oct 21
In certain embodiments, the present invention provides amplification methods in which nucleotide tag(s) and, optionally, a barcode nucleotide sequence are added to target nucleotide sequences.
Andrew May, Peilin Chen, Jun Wang, Fiona Kaper, Megan Anderson
Filed: 3 Feb 21
Utility
High-level multiplex amplification
14 Sep 21
The present disclosure provides a “looping amplification” method to increase the specificity of nucleic acid amplification.
Peilin Chen
Filed: 16 Dec 16
Utility
Parallelized Sample Processing and Library Prep
2 Sep 21
Described herein are methods, kits and systems for sample enrichment, multi-step library preparation, sample normalization, detection of sample biomolecules and combinations thereof.
Michael L. Phelan, Christopher J. Kubu, Brian Fowler, Gang Sun, Nikita Patel, Naveen Ramalingam
Filed: 22 Feb 21
Utility
Sample analysis for mass cytometry
24 Aug 21
The invention relates to methods and devices for analysis of samples using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS).
Alexandre Loboda
Filed: 8 Jun 20
Utility
Method for Capturing and Encoding Nucleic Acid from a Plurality of Single Cells
19 Aug 21
This invention relates to methods for capturing and encoding nucleic acid from a plurality of single cells.
Sten Linnarsson, Gioele Le Manno, Amit Zeisel
Filed: 8 Oct 20
Utility
Reagents and Methods for Elemental Mass Spectrometry of Biological Samples
5 Aug 21
Embodiments of the present invention relate to reagents and their use for elemental imaging mass spectrometry of biological samples.
Alexander V. Loboda, Olga Ornatsky, Vladimir Baranov, Nikita Zabinyakov, Anastasia Mavropoulos, Daniel Majonis, Bedilu Allo, Taunia Closson
Filed: 26 Apr 19
Utility
Methods and kits for extracting nucleic acids from paraffin embedded samples
3 Aug 21
This invention provides a technology for isolating nucleic acids from wax-embedded samples that is superior to the current state of the art.
Jian Qin, Peilin Chen, Ramesh Ramakrishnan
Filed: 20 Aug 18
Utility
Reagents and Methods for Elemental Imaging Mass Spectrometry of Biological Samples
17 Jun 21
The present disclosure relates to reagents and their use for elemental imaging mass spectrometry of biological samples.
Olga Ornatsky, Qing Chang, Bedilu Allo, Xudong Lou, Alexander Bouzekri
Filed: 8 Jun 18
Utility
High Resolution Imaging Apparatus and Method
22 Apr 21
The present invention relates to the high resolution imaging of samples using imaging mass spectrometry (IMS) and to the imaging of biological samples by imaging mass cytometry (IMCTM) in which labelling atoms are detected by IMS.
Paul Corkum, Alexander V. Loboda
Filed: 18 Jun 19
Utility
Single-cell nucleic acids for high-throughput studies
23 Mar 21
Described herein are cell-based analytic methods, including a method of incorporating nucleic acid sequences into reaction products from a cell population, wherein the nucleic acid sequences are incorporated into the reaction products of each cell individually or in small groups of cells individually.
Carolyn G. Conant, Tze Howe Charn, Jason A. A. West, Xiaohui Wang
Filed: 10 Dec 18
Utility
Methods and Devices for Analysis of Defined Multicellular Combinations
19 Aug 20
Methods for cell analysis are provided, comprising cell capturing, characterization, transport, and culture.
Jason A. A. West, Brian Fowler
Filed: 23 Jan 20
Utility
Optical lens system and method for microfluidic devices
17 Aug 20
In some embodiments, a variety of devices and methods for conducting microfluidic analyses are utilized herein, including devices that can be utilized to conduct thermal cycling reactions such as nucleic acid amplification reactions.
Marc A. Unger, Geoffrey Richard Facer, Barry Clerkson, Christopher G. Cesar, Neil Switz
Filed: 17 Sep 18
Utility
Mass Spectrometry Based Multi-Parametric Particle Analyzer
29 Jul 20
An analytical instrument has a sample introduction system for generating a stream of particles from a sample.
Dmitry R. Bandura, Vladimir I. Baranov, Scott D. Tanner
Filed: 8 Apr 20
Utility
Multi-primer Amplification Method for Tagging of Target Nucleic Acids
1 Apr 20
In certain embodiments, the present invention provides amplification methods in which nucleotide tag(s) and, optionally, a barcode nucleotide sequence are added to target nucleotide sequences.
Andrew May, Peilin Chen, Jun Wang, Fiona Kaper, Megan Anderson
Filed: 15 May 19
Utility
Methods and devices for analysis of defined multicellular combinations
2 Mar 20
Methods for cell analysis are provided, comprising cell capturing, characterization, transport, and culture.
Jason A. A. West, Brian Fowler
Filed: 13 Mar 14
Utility
Nucleic acid encoding reactions
9 Dec 19
Described herein are methods useful for incorporating one or more adaptors and/or nucleotide tag(s) and/or barcode nucleotide sequence(s) one, or typically more, target nucleotide sequences.
Megan Anderson, Peilin Chen, Brian Fowler, Robert C. Jones, Fiona Kaper, Ronald Lebofsky, Andrew May
Filed: 27 May 15
Utility
Simultaneous Detection of Target Protein and Target Nucleic Acids In a Single Cell
20 Nov 19
Methods and reagents for detection and analysis of nucleic acids are provided.
Robert C. Jones
Filed: 18 Dec 18
Utility
Method and Systems for Microfluidic Logic Devices
30 Oct 19
A microfluidic system includes a substrate, a set of input ports coupled to the substrate, and a set of output ports coupled to the substrate.
Naga Gopi Devaraju, Marc A. Unger
Filed: 4 Apr 19
Utility
Mass spectrometry based multi-parametric particle analyzer
7 Oct 19
An analytical instrument has a sample introduction system for generating a stream of particles from a sample.
Dmitry R. Bandura, Vladimir I. Baranov, Scott D. Tanner
Filed: 20 Dec 18