12 patents
Utility
Antifungal Agents with Enhanced Activity In Acidic PH
16 Nov 23
David A. Angulo Gonzalez
Filed: 18 Nov 22
Utility
Injectable Compositions of Triterpenoid Antifungals Encapsulated In Liposomes
7 Sep 23
Injectable compositions of single bilayer vesicles encapsulating enfumafungin derived triterpenoid antifungal compounds can be administered intravenously to treat or prevent fungal infections, while having reduced local injection site reactions (ISRs).
Rajeshwar Motheram
Filed: 4 Oct 22
Utility
Triterpenoid Antifungals for the Treatment or Prevention of Pneumocystis SPP. Pneumonia
18 May 23
Enfumafungin derivative triterpenoid antifungal compounds are used to treat and/or prevent Pneumocystis pneumonia (PCP) due to their unexpected efficacy against Pneumocystis spp. including their ability to reduce the lung burden of cyst and trophic forms of this fungi.
David A. Angulo Gonzalez, Stephen Andrew Barat
Filed: 25 Feb 20
Utility
Antifungal agents with enhanced activity in acidic pH
27 Dec 22
Enfumafungin derivative triterpenoid antifungal compounds are used to treat or prevent fungal infections occurring in or under acidic conditions where the pH is lower than about 7, due to their unexpected, enhanced efficacy under such conditions.
David A. Angulo Gonzalez
Filed: 31 Jul 18
Utility
Antifungal Agents Used In Combination
30 Jun 22
The present invention relates to the use of enfumafungin derivative triterpenoid antifungal compounds in combination with other antifungal agents such azoles, polyenes, lipopeptides, and allylamides to treat fungal diseases.
David A. Angulo Gonzalez
Filed: 10 Aug 21
Utility
Triterpenoid Antifungals for the Treatment of Fungal Osteo-articular Infections
21 Apr 22
Enfumafungin derivative triterpenoid antifungal compounds are used to treat osteo-articular fungal infections, due to their unexpected bone tissue penetration and associated efficacy for such infections.
David A. Angulo Gonzalez
Filed: 30 Jan 20
Utility
Novel Salts and Polymorphs of SCY-078
23 Dec 21
SCY-078 is a glucan synthase inhibitor with antimicrobial activity.
YI ZHANG
Filed: 29 Jan 21
Utility
Antifungal agents used in combination
7 Sep 21
The present invention relates to the use of enfumafungin derivative triterpenoid antifungal compounds in combination with other antifungal agents such azoles, polyenes, lipopeptides, and allylamides to treat fungal diseases.
David A. Angulo Gonzalez
Filed: 4 Apr 18
Utility
Salts and polymorphs of SCY-078
23 Feb 21
SCY-078 is a glucan synthase inhibitor with antimicrobial activity.
Yi Zhang
Filed: 11 Jun 19
Utility
Antifungal Agents with Enhanced Activity In Acidic PH
16 Dec 20
Enfumafungin derivative triterpenoid antifungal compounds are used to treat or prevent fungal infections occurring in or under acidic conditions where the pH is lower than about 7, due to their unexpected, enhanced efficacy under such conditions.
David A. ANGULO GONZALEZ
Filed: 30 Jul 18
Utility
Injectable Compositions of Triterpenoid Antifungals Encapsulated In Liposomes
28 Oct 20
Injectable compositions of single bilayer vesicles encapsulating enfumafungin derived triterpenoid antifungal compounds can be administered intravenously to treat or prevent fungal infections, while having reduced local injection site reactions (ISRs).
Rajeshwar Motheram
Filed: 20 Dec 18
Utility
Novel Salts and Polymorphs of SCY-078
27 Nov 19
SCY-078 is a glucan synthase inhibitor with antimicrobial activity.
Yi ZHANG
Filed: 10 Jun 19
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