7 patents
Utility
Ganaxolone for use in treating tuberous sclerosis complex
18 Jul 23
The disclosure to methods for treating tuberous sclerosis complex or tuberous sclerosis complex-related epilepsy, comprising administering to a subject in need thereof a therapeutically effective amount of a pharmaceutically acceptable pregnenolone neurosteroid, such as ganaxolone, to reduce one or more symptoms of tuberous sclerosis complex or tuberous sclerosis complex-related epilepsy.
Alex Aimetti, Joseph Hulihan, Scott Braunstein
Filed: 1 Mar 22
Utility
Ganaxolone for use in prophylaxis and treatment of postpartum depression
8 Mar 22
Uses of ganaxolone in prophylaxis and treatment of postpartum depression are described.
Alex Aimetti, Christopher Cashman, Lorianne Masuoka, Jaakko Lappalainen
Filed: 6 Dec 19
Utility
Ganaxolone for use in treatment of status epilepticus
7 Sep 21
This invention relates to methods for treating status epilepticus by administering to the subject in need thereof an intravenous bolus of ganaxolone and a continuous intravenous infusion of a neurosteroid.
David Czekai, Maciej Gasior, Lorianne Masuoka, Julia Tsai, Joseph Hulihan, Alex Aimetti
Filed: 26 Feb 21
Utility
Method of treatment using nanoparticulate ganaxolone formulations
27 Jul 21
In certain embodiments, the invention is directed to composition comprising stable particles comprising ganaxolone, wherein the volume weighted median diameter (D50) of the particles is from about 50 nm to about 500 nm.
Kenneth Shaw, Mingbao Zhang
Filed: 2 Oct 18
Utility
Methods of treating certain depressive disorders and delirium tremens
11 May 21
The disclosure provides a method of treating a patient having postpartum depression, premenstrual dysphoric disorder, menopausal depression, or delirium tremens comprising administering an effective amount of an injectable neurosteroid formulation to the patient.
Christopher Cashman, Jaakko Lappalainen, David A. Czekai
Filed: 25 Mar 20
Utility
Injectable neurosteroid formulations containing nanoparticles
21 Sep 20
Mingbao Zhang, Raymond C. Glowaky, David Czekai
Filed: 13 Oct 16
Utility
Methods of treating certain depressive disorders and delirium tremens
4 May 20
The disclosure provides a method of treating a patient having postpartum depression, premenstrual dysphoric disorder, menopausal depression, or delirium tremens comprising administering an effective amount of an injectable neurosteroid formulation to the patient.
Christopher Cashman, Jaakko Lappalainen, David A Czekai
Filed: 2 Oct 18
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