50 patents
Page 2 of 3
Utility
Bcma Chimeric Antigen Receptors
18 Mar 21
The invention provides improved compositions for adoptive T cell therapies for B cell related conditions.
Richard MORGAN, Kevin FRIEDMAN
Filed: 23 Oct 20
Utility
Bcma Chimeric Antigen Receptors
25 Feb 21
The invention provides improved compositions for adoptive T cell therapies for B cell related conditions.
Richard MORGAN, Kevin FRIEDMAN
Filed: 23 Oct 20
Utility
Bcma Chimeric Antigen Receptors
11 Feb 21
The invention provides improved compositions for adoptive T cell therapies for B cell related conditions.
Richard MORGAN, Kevin FRIEDMAN
Filed: 23 Oct 20
Utility
PD-1 Homing Endonuclease Variants, Compositions, and Methods of Use
11 Feb 21
The present disclosure provides improved genome editing compositions and methods for editing a PD-1 gene.
Jasdeep MANN, Joel GAY, Jordan JARJOUR, Joy ZHANG
Filed: 8 Sep 17
Utility
MND Promoter Chimeric Antigen Receptors
4 Feb 21
The invention provides vector compositions for delivering improved adoptive T cell therapies.
Richard MORGAN, Kevin FRIEDMAN, Byoung RYU
Filed: 7 Aug 20
Utility
CTLA4 Homing Endonuclease Variants, Compositions, and Methods of Use
6 Jan 21
The present disclosure provides improved genome editing compositions and methods for editing a CTLA4 gene.
JORDAN JARJOUR, KYLE HAVENS
Filed: 19 Dec 18
Utility
Daric Interleukin Receptors
16 Dec 20
The present disclosure provides improved compositions for adoptive T cell therapies for treating, preventing, or ameliorating at least one symptom of a cancer, infectious disease, autoimmune disease, inflammatory disease, and immunodeficiency, or condition associated therewith.
WAI-HANG LEUNG
Filed: 13 Dec 18
Utility
PCSK9 Endonuclease Variants, Compositions, and Methods of Use
2 Dec 20
The present disclosure provides improved genome editing compositions and methods for editing a PCSK9 gene.
JORDAN JARJOUR, KYLE HAVENS, MICHAEL CERTO, MAX ECHTERLING
Filed: 3 Oct 18
Utility
Therapeutic Retroviral Vectors for Gene Therapy
25 Nov 20
Provided are improved compositions and methods for achieving gene therapy in hematopoietic cells and hematopoietic precursor cells, including erythrocytes, erythroid progenitors, and embryonic stem cells.
Philippe Louis LEBOULCH, Robert PAWLIUK, Karen WESTERMAN
Filed: 15 Mar 20
Utility
Sickled Beta Globin Antibodies
4 Nov 20
The invention generally provides improved anti-sickled-globin antibodies and fragments thereof.
Olivier NEGRE
Filed: 13 Dec 18
Utility
Bcma Chimeric Antigen Receptors
21 Oct 20
The invention provides improved compositions for adoptive T cell therapies for B cell related conditions.
Richard MORGAN, Kevin FRIEDMAN
Filed: 31 Mar 20
Utility
Anti-bcma Car T Cell Compositions
19 Aug 20
The invention provides improved anti-BCMA CAR T cell compositions for adoptive T cell therapy for relapsed/refractory multiple myeloma.
Travis QUIGLEY, Robert ROSS
Filed: 2 Nov 17
Utility
TGFBetaR2 ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USE
22 Apr 20
The present disclosure provides improved genome editing compositions and methods for editing a TGFβR2 gene.
Jordan JARJOUR, Kyle HAVENS
Filed: 16 Oct 17
Utility
CBLB Endonuclease Variants, Compositions, and Methods of Use
8 Apr 20
The present disclosure provides improved genome editing compositions and methods for editing a CBLB gene.
Jordan JARJOUR, Kyle HAVENS, Anne-Rachel KROSTAG
Filed: 24 Nov 19
Utility
Methods of Making T Cell Compositions
8 Apr 20
The invention provides improved T cell compositions and methods for manufacturing T cells.
Kevin Friedman
Filed: 8 Oct 19
Utility
Vectors and Compositions for Treating Hemoglobinopathies
8 Apr 20
The invention provides improved gene therapy vectors, compositions, and methods.
Gabor VERES, David A. WILLIAMS
Filed: 28 Mar 18
Utility
CBLB Endonuclease Variants, Compositions, and Methods of Use
18 Mar 20
The present disclosure provides improved genome editing compositions and methods for editing a CBLB gene.
Jordan JARJOUR, Kyle HAVENS, Anne-Rachel KROSTAG
Filed: 24 Nov 19
Utility
Bcma Chimeric Antigen Receptors
11 Mar 20
The invention provides improved compositions for adoptive T cell therapies for B cell related conditions.
Richard MORGAN, Kevin Friedman
Filed: 17 Jul 19
Utility
Gene Therapy for Mucopolysaccharidosis, Type II
4 Mar 20
The invention provides compositions and methods for treating Hunter Syndrome.
Kendrick A. GOSS, Geoffrey B. PARSONS
Filed: 5 Dec 17
Utility
Multipartite Signaling Proteins and Uses Thereof
4 Mar 20
The present disclosure relates to compositions and methods for using cells having chemically-induced fusion protein complexes to spatially and temporally control immune cell signal initiation and downstream responses for treating disease.
Jordan JARJOUR, Alexander ASTRAKHAN, Michael CERTO
Filed: 16 Sep 19