16 patents
Utility
Method of Treating Graft Versus Hot Disease
2 Nov 23
A method for preventing the development of or treating GvHD complications in a mammalian patient which comprises administering to the mammal a population of cells enriched for STRO-1bright cells and/or progeny thereof and/or soluble factors derived therefrom.
Silviu Itescu, Michael David Schuster
Filed: 29 Mar 23
Utility
Repair And/or Reconstitution of Invertebral Discs
16 Mar 23
This invention relates to a method for repair and reconstitution of invertebral discs in a subject which involves administration of STRO-1′ multipotent cells.
Peter Ghosh
Filed: 28 Jul 22
Utility
Methods of Generating, Repairing And/or Maintaining Connective Tissue In Vivo
10 Nov 22
This invention relates to a method for generating, repairing and/or maintaining connective tissue in a subject.
Peter Ghosh
Filed: 26 Jul 22
Utility
Multipotential Expanded Mesenchymal Precursor Cell Progeny (MEMP) and Uses Thereof
18 Nov 21
The invention relates to multipotential expanded mesenchymal precursor progeny (MEMP's), characterised by the early developmental markers STRO-1bri and ALP.
Stan Gronthos, Andrew Christopher William Zannettino
Filed: 7 Jul 21
Utility
Methods for increasing osteoblastic function
5 Oct 21
This application provides methods for treating a human subject suffering from a bone fracture by administering to the subject a population of cells enriched from STRO-1+ multipotential cells and/or multipotential progeny of such cells.
Silviu Itescu, Ravi Krishnan
Filed: 2 Jul 19
Utility
Method of Treating the Effects of Stroke
29 Jul 21
The present disclosure provides methods of improving cerebral function or preventing loss of cerebral function and/or treating or preventing a movement disorder and/or regenerating cerebral neurons in a subject who has suffered a stroke, the method comprising administering to the subject a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.
Simon Andrea Koblar, Stan Gronthos, Agnieszka Arthur
Filed: 8 Mar 21
Utility
Methods of Treating or Preventing Neurological Diseases
10 Jun 21
The present disclosure provides a method for treating an inflammatory neurological disease comprising administering a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.
Claude Bernard
Filed: 16 Feb 21
Utility
Method of Treating Graft Versus Host Disease
25 Mar 21
A method for preventing the development of or treating GvHD complications in a mammalian patient which comprises administering to the mammal a population of cells enriched for STRO-1bright cells and/or progeny thereof and/or soluble factors derived therefrom.
Silviu Itescu, Michael David Schuster
Filed: 22 Oct 20
Utility
Method of treating graft versus host disease
30 Nov 20
A method for preventing the development of or treating GvHD complications in a mammalian patient which comprises administering to the mammal a population of cells enriched for STRO-1bright cells and/or progeny thereof and/or soluble factors derived therefrom.
Silviu Itescu, Michael David Schuster
Filed: 13 Sep 18
Utility
Isolation of Adult Multipotential Cells by Tissue Non-specific Alkaline Phosphatase
21 Oct 20
The present invention relates to the use of tissue non-specific alkaline phosphatase (TNAP) as a marker for identifying and/or isolating adult multipotential cells.
Stan Gronthos, Andrew Christopher William Zannettino, John Paul Simmons
Filed: 4 May 20
Utility
Methods of Treating or Preventing Respiratory Conditions
16 Sep 20
The present disclosure provides methods of treating or preventing respiratory condition and/or for treating an IgE-mediated allergy and/or for reducing an allergic response to an allergen and/or for inducing anergy to an allergen in a subject and/or improving lung function in a subject suffering from an allergy comprising administering to a subject a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.
Silviu Itescu, Ravi Krishnan, Peter Ghosh
Filed: 31 May 20
Utility
Methods of treating or preventing respiratory conditions
22 Jun 20
The present disclosure provides methods of treating or preventing respiratory condition and/or for treating an IgE-mediated allergy and/or for reducing an allergic response to an allergen and/or for inducing anergy to an allergen in a subject and/or improving lung function in a subject suffering from an allergy comprising administering to a subject a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.
Silviu Itescu, Ravi Krishnan, Peter Ghosh
Filed: 15 Jul 18
Utility
Methods of Generating, Repairing And/or Maintaining Connective Tissue In Vivo
1 Apr 20
This invention relates to a method for generating, repairing and/or maintaining connective tissue in a subject.
Peter Ghosh
Filed: 26 Sep 19
Utility
Methods of treating or preventing rheumatic disease
23 Mar 20
The present disclosure provides a method for treating or preventing a rheumatic disease, comprising administering a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.
Peter Ghosh, Silviu Itescu
Filed: 16 Apr 18
Utility
Method of increasing proliferation of bone marrow mononuclear cells expressing STRO1-
27 Jan 20
The present invention relates to methods of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC) and/or progeny derived therefrom in vitro or in vivo comprising exposing the MPC or progeny to SDF-1 or analog thereof.
Stan Gronthos, Andrew Christopher William Zannettino
Filed: 26 Aug 14
Utility
Methods for Increasing Osteoblastic Function
13 Nov 19
This application provides methods for treating a human subject suffering from a bone fracture by administering to the subject a population of cells enriched from STRO-1+ multipotential cells and/or multipotential progeny of such cells.
Silviu Itescu, Ravi Krishnan
Filed: 1 Jul 19
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