41 patents
Utility
Compounds, Compositions, and Methods for Recovering Water-immiscible Compounds from Microbial Biomass
19 Oct 23
Provided herein are compounds, compositions, and methods for recovery of one or more water-immiscible compounds from microbial biomass.
Ronald Ray HENRY, Joshua Steven LENG
Filed: 25 Apr 22
Utility
Vaccine Adjuvants and Methods of Synthesizing and Using the Same
12 Oct 23
The disclosure provides compounds useful as adjuvants in vaccines, as well as methods of synthesizing such compounds and methods of using such compounds in the formulation of a vaccine.
Christopher John PADDON, Karl Joseph FISHER
Filed: 7 Jul 21
Utility
Microbial Production of Cannabinoids
28 Sep 23
The compositions and methods of the disclosure can be used to produce a cannabinoid in a host cell, such as a yeast cell.
Victor F. HOLMES, John E. HUNG, Irina A. KORYAKINA, Andrew P. KLEIN, Yi XIONG, William E. DRAPER, Hailley S. WARBINGTON
Filed: 19 Aug 21
Utility
Metal Oxide Sunscreen Formulations
31 Aug 23
Provided herein are sunscreen formulations containing a metal oxide sunscreen, squalane, and an antioxidant.
CHRISTA LYNNA MARIANO, RAMYA VISWANATHAN
Filed: 30 Jun 21
Utility
Rebaudioside M Sweetener Compositions
30 Mar 23
Provided herein are high potency sweeteners containing at least 95% rebaudioside M generated from Saccharomyces cerevisiae strains engineered to produce high purity rebaudioside M when fermented with sugar cane syrup.
Stanley W. Herrmann, Binita Bhattacharjee, Rhodri Jenkins, Brian Yip, Alex Woo
Filed: 12 Mar 21
Utility
Metal Oxide Sunscreen Formulations
23 Mar 23
Provided herein are sunscreen formulations containing a metal oxide sunscreen, squalane, and an antioxidant.
Christa Lynna MARIANO, Ramya VISWANATHAN
Filed: 29 Jan 21
Utility
Antiperspirant Formulations Comprising Hemisqualane
2 Mar 23
Provided herein antiperspirant composition formulations that contain hemisqualane and lack organosilicon compounds.
Diva CHAN, RO OTERI, Ashlee NUNES
Filed: 6 Nov 20
Utility
AMORPHA-4,11-DIENE 12-MONOOXYGENASE Variants and Uses Thereof
2 Mar 23
Provided herein are genetically modified host cells, compositions, and methods for improved production of artemisinic acid.
Christopher J. PADDON, Hanxiao JIANG, Stephanie H. KUNG
Filed: 22 Jan 21
Utility
Compositions and Methods for Delivering Cannabinoids to Skin
17 Nov 22
Provided herein are compositions for delivering one or more cannabinoids to the skin of a subject and methods of using the compositions to deliver the one or more cannabinoids to the skin of a subject.
Diva CHAN, Ro OTERI, Ashlee NUNES
Filed: 6 Nov 20
Utility
Methods for Genomic Integration
13 Oct 22
Provided herein are methods of integrating one or more exogenous nucleic acids into one or more selected target sites of a host cell genome.
Andrew HORWITZ, Kristy Michelle HAWKINS, Max SCHUBERT, Wayne SZETO
Filed: 14 Jun 22
Utility
Methods for Genomic Integration In Pichia and Other Host Cells
6 Oct 22
The present invention provides high efficiency targeted and marker-less single, double, triple, quadruple, and quintuple integrations by using CRISPR in host cells, including Pichia.
Hanxiao JIANG
Filed: 15 Jun 22
Utility
Methods for Decoupling Yield and Productivity of a Non-catabolic Compound Produced by a Host Cell
29 Sep 22
Provided herein are compositions and methods for uncoupling the yield and productivity of an isoprenoid compound produced in a host cell.
Penelope R. CHUA, Joshua Adam LERMAN, Thomas Jon SCHERBART, Chandresh THAKKER, Annie Ening TSONG, Hanxiao JIANG
Filed: 5 Jun 20
Utility
Improved Oligosaccharide Production In Yeast
22 Sep 22
Provided herein are genetically modified yeast cells capable of producing one or more human milk oligosaccharides (HMOs) and methods of making such cells.
Jessica WALTER, Dominic PINEL
Filed: 13 Aug 20
Utility
Kaurenoic Acid 13-HYDROXYLASE (Kah) Variants and Uses Thereof
8 Sep 22
Provided herein are genetically modified host cells, compositions, and methods for improved production of steviol glycosides.
Andrew P. KLEIN, Sean LUND, Gale WICHMANN, Irina KORYAKINA, Kyle HOGAN, Svetlana BORISOVA
Filed: 1 May 20
Utility
Modified Host Cells for High Efficiency Production of Vanillin
8 Sep 22
Provided herein are genetically modified host cells, compositions, and methods for improved production of vanillin and/or glucovanillin.
Lauren RAETZ, Chad HANSEN
Filed: 31 Jul 20
Utility
Compositions and Methods for Genomic Integration of Nucleic Acids into Exogenous Landing Pads
11 Aug 22
Provided herein are compositions and methods of integrating one or more exogenous donor nucleic acids into one or more exogenous landing pads engineered into a host cell's genome.
Kevin GEORGE, Andrew MAIN, Chia-Hong TSAI
Filed: 9 Mar 22
Utility
Microbial Production of Compounds
28 Apr 22
Provide are modified host cells that are engineered to decrese expression of a product to undetectable levels in the presence of an exogenous agent, and increase expression of the product in the presence of another exogenous agent.
Christopher D. REEVES, Christopher J. PADDON, Victor F. HOLMES, Andrew P. KLEIN
Filed: 13 Mar 20
Utility
Compositions and Methods for Production of Myrcene
6 Jan 22
Provided herein are compositions and methods for producing myrcene by culturing genetically modified microbial host cells that express a myrcene synthase and optionally a geranyl pyroplosphate synthase.
Andrew MAIN, Grzegorz WOJCIECHOWSKI, Yue YANG, Lishan ZHAO
Filed: 9 Jul 21
Utility
Stevia Rebaudiana Kaurenoic Acid Hydroxylase Variants for High Efficiency Production of Rebaudiosides
2 Dec 21
Provided herein are compositions and methods for improved production of steviol glycosides in a host cell.
Gale A. WICHMANN, Wenzong LI, Sean LUND, Shaina J. JACKSON, Chantal V. GARCIA DE GONZALO, Hailley WARBINGTON, Yi XIONG, Svetlana Alekseyevna BORISOVA
Filed: 14 Oct 19
Utility
Udp-dependent Glycosyltransferase for High Efficiency Production of Rebaudiosides
18 Nov 21
Provided herein are compositions and methods for improved production of steviol glycosides in a host cell.
Lishan ZHAO, Wenzong LI, Gale WICHMANN, Aditi KHANKHOJE, Chantal GARCIA DE GONZALO, Tina MAHATDEJKUL-MEADOWS, Shaina JACKSON, Michael LEAVELL, Darren PLATT
Filed: 22 Jul 21