9 patents
Utility
Antibodies directed against T cell immunoglobulin and mucin protein 3 (TIM-3)
12 Sep 23
Provided herein are anti-T Cell Immunoglobulin and Mucin Protein-3 (TIM 3) antibodies having particular immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide sequences and methods of using the anti-TIM-3 antibodies to treat a disorder or disease that is responsive to TIM-3 inhibition, such as cancer, an infectious disease, or an autoimmune disease.
David J. King, Marilyn Kehry, Srimoyee Ghosh, Baochuan Huang
Filed: 27 Oct 21
Utility
Antibodies directed against T Cell immunoglobulin and mucin protein 3 (TIM-3)
7 Jun 22
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the T Cell Immunoglobulin and Mucin Protein-3 (TIM-3).
Marilyn Kehry, David J. King, Jean Da Silva Correia
Filed: 17 Oct 19
Utility
Antibodies directed against programmed death-1 (PD-1)
26 Oct 21
The disclosure provides antibody agents that bind to a programmed death-1 (PD-1) protein.
David J. King, Marilyn Kehry, Baochuan Huang
Filed: 1 Nov 17
Utility
Method of treating pustular psoriasis with antibodies directed against interleukin 36 receptor (IL-36R)
28 Sep 21
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the interleukin 36 receptor (IL-36R).
Peter Bowers, Andrew John McKnight, David J. King, Marco Londei
Filed: 18 Nov 19
Utility
Method of treating inflammatory disorder with antibodies directed against interleukin-33 (IL-33)
16 Nov 20
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to interleukin-33 (IL-33).
Robert A. Horlick, David J. King, Andrew John McKnight
Filed: 22 Jul 18
Utility
Antibodies directed against lymphocyte activation gene 3 (LAG-3)
16 Nov 20
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the Lymphocyte Activation Gene-3 (LAG-3).
Helen Toni Jun, Marilyn Kehry, Peter Bowers, David J. King
Filed: 2 Feb 16
Utility
Antibodies directed against programmed death-1 (PD-1)
10 Aug 20
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a programmed death-1 (PD-1) protein.
David J. King, Marilyn Kehry
Filed: 4 Oct 17
Utility
Antibodies directed against interleukin 36 receptor (IL-36R)
6 Jan 20
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the interleukin 36 receptor (IL-36R).
Peter Bowers, Andrew John McKnight, David J. King, Marco Londei
Filed: 14 Apr 16
Utility
Antibodies directed against T cell immunoglobulin and mucin protein 3 (TIM-3)
16 Dec 19
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the T Cell Immunoglobulin and Mucin Protein-3 (HM-3).
Marilyn Kehry, David J. King, Jean Da Silva Correia
Filed: 31 Mar 16
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