23 patents
Utility
Reduction of bias in genomic coverage measurements
3 Oct 23
Methods are provided for detecting and quantitating molecules using fluidics.
{hacek over (Z)}eljko D{hacek over (z)}akula
Filed: 20 Nov 20
Utility
Nanonozzle Device Arrays: Their Preparation and Use for Macromolecular Analysis
27 Apr 23
Constricted nanochannel devices suitable for use in analysis of macromolecular structure, including DNA sequencing, are disclosed.
Han Cao, Parikshit A. Deshpande, Michael David Austin, Michael Boyce-Jacino
Filed: 16 Nov 22
Utility
Nanonozzle device arrays: their preparation and use for macromolecular analysis
20 Dec 22
Constricted nanochannel devices suitable for use in analysis of macromolecular structure, including DNA sequencing, are disclosed.
Han Cao, Parikshit A. Deshpande, Michael David Austin, Michael Boyce-Jacino
Filed: 1 Jun 20
Utility
Integrated Analysis Devices and Related Fabrication Methods and Analysis Techniques
8 Dec 22
Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices.
Han Cao, Michael David Austin, Parikshit A. Deshpande, Mark Kunkel, Alexey Y. Sharonov, Michael Kochersperger
Filed: 21 Mar 22
Utility
Characterization of Molecules In Nanofluidics
27 Oct 22
Systems are provided for detecting and quantitating short nucleic acid molecules.
Han Cao, Alex R. Hastie, Ernest Tsz-Tsun Lam
Filed: 11 May 22
Utility
Photocleavage Method and Apparatus to Clean Fluidic Devices
21 Jul 22
A method and system for improving throughput of a fluidic system such as a biopolymer analysis system by cleaning accumulated or clogging biopolymer from the fluidic system is disclosed.
David Xian Wei Yao, William K. Ridgeway
Filed: 9 Mar 22
Utility
Characterization of molecules in nanofluidics
14 Jun 22
Methods are provided for detecting and quantitating molecules using fluidics.
Han Cao, Alex R. Hastie, Ernest Tsz-Tsun Lam
Filed: 29 May 20
Utility
Photocleavage method and apparatus to clean fluidic devices
5 Apr 22
A method and system for improving throughput of a fluidic system such as a biopolymer analysis system by cleaning accumulated or clogging biopolymer from the fluidic system is disclosed.
David Xian Wei Yao, William K. Ridgeway
Filed: 31 Aug 15
Utility
Integrated analysis device analysis techniques
5 Apr 22
Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices.
Han Cao, Michael David Austin, Parikshit A. Deshpande, Mark Kunkel, Alexey Y. Sharonov, Michael Kochersperger
Filed: 1 May 20
Utility
Methods and Devices for Single-molecule Whole Genome Analysis
20 Jan 22
Provided are methods and devices for single-molecule genomic analysis.
Ming H. Xiao, Han Cao
Filed: 23 Mar 21
Utility
Labeling of Dna
29 Jul 21
Methods of labeling DNA molecules comprising the use of one or more dCas proteins and one or more labeled guide RNAs (gRNAs) are described herein.
Alex R. Hastie, Denghong Zhang
Filed: 24 Jun 19
Utility
Reduction of Bias In Genomic Coverage Measurements
20 May 21
Methods are provided for detecting and quantitating molecules using fluidics.
Zeljko Dzakula
Filed: 20 Nov 20
Utility
Methods and devices for single-molecule whole genome analysis
4 May 21
Provided are methods and devices for single-molecule genomic analysis.
Ming H. Xiao, Han Cao
Filed: 4 Oct 19
Utility
Integrated Analysis Devices and Related Fabrication Methods and Analysis Techniques
8 Apr 21
Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices.
Han Cao, Michael David Austin, Parikshit A. Deshpande, Mark Kunkel, Alexey Y. Sharonov, Michael Kochersperger
Filed: 1 May 20
Utility
Nanonozzle Device Arrays: Their Preparation and Use for Macromolecular Analysis
25 Feb 21
Constricted nanochannel devices suitable for use in analysis of macromolecular structure, including DNA sequencing, are disclosed.
Han Cao, Parikshit A. Deshpande, Michael David Austin, Michael Boyce-Jacino
Filed: 1 Jun 20
Utility
Methods of Determining Nucleic Acid Structural Information
14 Jan 21
Methods of double-stranded nucleic acid sequence determination and assembly that are able to identify insertions, deletions, repeat region sizes and genomic rearrangements, for example, are disclosed herein, which can use relatively large labeled nucleic acid fragments to analyze the structure of even larger genetic regions.
Michael G. Saghbini, Henry B. Sadowski, Goran Pljevaljcic, Alex R. Hastie, Han Cao
Filed: 23 Jun 20
Utility
Reduction of bias in genomic coverage measurements
23 Nov 20
Methods are provided for detecting and quantitating molecules using fluidics.
{hacek over (Z)}eljko D{hacek over (z)}akula
Filed: 23 Feb 15
Utility
Characterization of Molecules In Nanofluidics
18 Nov 20
Methods are provided for detecting and quantitating molecules using fluidics.
Han Cao, Alex R. Hastie, Ernest Tsz-Tsun Lam
Filed: 28 May 20
Utility
Methods and Devices for Single-molecule Whole Genome Analysis
26 Aug 20
Provided are methods and devices for single-molecule genomic analysis.
Ming H. Xiao, Han Cao
Filed: 3 Oct 19
Utility
Nanonozzle device arrays: their preparation and use for macromolecular analysis
8 Jun 20
Constricted nanochannel devices suitable for use in analysis of macromolecular structure, including DNA sequencing, are disclosed.
Han Cao, Parikshit A. Deshpande, Michael David Austin, Michael Boyce-Jacino
Filed: 31 Oct 17